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ENCODE cell lines, expression (Ernst 2011)

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Results for CEBPG

Z-value: 1.06

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.4 CEBPG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg19_v2_chr19_+_33865218_338652540.342.0e-01Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_186330712 5.15 ENST00000411641.2
ENST00000273784.5
 AHSG
 alpha-2-HS-glycoprotein
chr3_-_148939835 4.84 ENST00000264613.6
 CP
 ceruloplasmin (ferroxidase)
chr4_+_74269956 4.72 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
 ALB
 albumin
chr9_+_117092149 4.52 ENST00000431067.2
ENST00000412657.1
 ORM2
 orosomucoid 2
chr2_-_21266935 4.29 ENST00000233242.1
 APOB
 apolipoprotein B
chr9_+_117085336 4.08 ENST00000259396.8
ENST00000538816.1
 ORM1
 orosomucoid 1
chr19_-_6720686 3.73 ENST00000245907.6
 C3
 complement component 3
chr13_-_46679185 3.54 ENST00000439329.3
 CPB2
 carboxypeptidase B2 (plasma)
chr13_-_46679144 3.51 ENST00000181383.4
 CPB2
 carboxypeptidase B2 (plasma)
chr8_+_97597148 3.40 ENST00000521590.1
 SDC2
 syndecan 2
chr6_+_31895254 3.36 ENST00000299367.5
ENST00000442278.2
 C2
 complement component 2
chr17_-_64225508 3.31 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr2_+_11674213 3.30 ENST00000381486.2
 GREB1
 growth regulation by estrogen in breast cancer 1
chr6_+_31895467 2.97 ENST00000556679.1
ENST00000456570.1
 CFB
CFB
 complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895480 2.88 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
 C2
CFB
 complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr4_+_184020398 2.54 ENST00000403733.3
ENST00000378925.3
 WWC2
 WW and C2 domain containing 2
chr16_+_72088376 2.26 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
 HP
HPR
 haptoglobin
haptoglobin-related protein
chrX_+_46937745 2.21 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
 RGN
 regucalcin
chr11_-_18258342 2.20 ENST00000278222.4
 SAA4
 serum amyloid A4, constitutive
chr3_-_49726486 2.04 ENST00000449682.2
 MST1
 macrophage stimulating 1 (hepatocyte growth factor-like)
chr17_-_42200958 1.96 ENST00000336057.5
 HDAC5
 histone deacetylase 5
chr17_-_42200996 1.79 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
 HDAC5
 histone deacetylase 5
chr2_+_102721023 1.60 ENST00000409589.1
ENST00000409329.1
 IL1R1
 interleukin 1 receptor, type I
chr3_-_194072019 1.52 ENST00000429275.1
ENST00000323830.3
 CPN2
 carboxypeptidase N, polypeptide 2
chr18_+_33767473 1.49 ENST00000261326.5
 MOCOS
 molybdenum cofactor sulfurase
chr17_-_79895154 1.29 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
 PYCR1
 pyrroline-5-carboxylate reductase 1
chr17_-_79895097 1.19 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
 PYCR1
 pyrroline-5-carboxylate reductase 1
chr5_-_121413974 1.15 ENST00000231004.4
 LOX
 lysyl oxidase
chr12_-_71551868 1.12 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr3_+_186435137 1.11 ENST00000447445.1
 KNG1
 kininogen 1
chr6_+_167704798 1.09 ENST00000230256.3
 UNC93A
 unc-93 homolog A (C. elegans)
chr12_-_96390063 1.04 ENST00000541929.1
 HAL
 histidine ammonia-lyase
chr6_+_167704838 1.04 ENST00000366829.2
 UNC93A
 unc-93 homolog A (C. elegans)
chr19_-_4540486 1.03 ENST00000306390.6
 LRG1
 leucine-rich alpha-2-glycoprotein 1
chr2_-_216300784 0.99 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
 FN1
 fibronectin 1
chr8_-_121824374 0.92 ENST00000517992.1
 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chrX_+_49644470 0.92 ENST00000508866.2
 USP27X
 ubiquitin specific peptidase 27, X-linked
chr20_+_361261 0.88 ENST00000217233.3
 TRIB3
 tribbles pseudokinase 3
chr12_-_71551652 0.84 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr12_-_96390108 0.75 ENST00000538703.1
ENST00000261208.3
 HAL
 histidine ammonia-lyase
chr12_+_57522258 0.74 ENST00000553277.1
ENST00000243077.3
 LRP1
 low density lipoprotein receptor-related protein 1
chr9_+_80912059 0.73 ENST00000347159.2
ENST00000376588.3
 PSAT1
 phosphoserine aminotransferase 1
chr10_-_116444371 0.73 ENST00000533213.2
ENST00000369252.4
 ABLIM1
 actin binding LIM protein 1
chr2_-_112614424 0.72 ENST00000427997.1
 ANAPC1
 anaphase promoting complex subunit 1
chr1_-_161277210 0.70 ENST00000491222.2
 MPZ
 myelin protein zero
chr4_-_10023095 0.68 ENST00000264784.3
 SLC2A9
 solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_2699697 0.68 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chrX_-_73512411 0.66 ENST00000602576.1
ENST00000429124.1
 FTX
 FTX transcript, XIST regulator (non-protein coding)
chr22_-_31364187 0.65 ENST00000215862.4
ENST00000397641.3
 MORC2
 MORC family CW-type zinc finger 2
chr6_-_135271260 0.63 ENST00000265605.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr21_-_35899113 0.60 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
 RCAN1
 regulator of calcineurin 1
chr17_-_61850894 0.59 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
 CCDC47
 coiled-coil domain containing 47
chr3_+_73110810 0.58 ENST00000533473.1
 EBLN2
 endogenous Bornavirus-like nucleoprotein 2
chrX_+_47082408 0.55 ENST00000518022.1
ENST00000276052.6
 CDK16
 cyclin-dependent kinase 16
chr17_-_76124711 0.52 ENST00000306591.7
ENST00000590602.1
 TMC6
 transmembrane channel-like 6
chr6_-_135271219 0.50 ENST00000367847.2
ENST00000367845.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr6_-_27799305 0.49 ENST00000357549.2
 HIST1H4K
 histone cluster 1, H4k
chr20_-_48782639 0.45 ENST00000435301.2
 RP11-112L6.3
 RP11-112L6.3
chr21_+_34775181 0.45 ENST00000290219.6
 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_+_52682052 0.44 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr1_+_245133062 0.44 ENST00000366523.1
 EFCAB2
 EF-hand calcium binding domain 2
chr1_+_110162448 0.37 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
 AMPD2
 adenosine monophosphate deaminase 2
chr10_-_92681033 0.35 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr4_+_71226468 0.35 ENST00000226460.4
 SMR3A
 submaxillary gland androgen regulated protein 3A
chr6_-_30710510 0.32 ENST00000376389.3
 FLOT1
 flotillin 1
chr14_+_39703084 0.29 ENST00000553728.1
 RP11-407N17.3
 cTAGE family member 5 isoform 4
chr3_+_40498783 0.28 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
 RPL14
 ribosomal protein L14
chr6_-_30710447 0.27 ENST00000456573.2
 FLOT1
 flotillin 1
chr5_+_36152163 0.27 ENST00000274255.6
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr17_+_34900737 0.26 ENST00000304718.4
ENST00000485685.2
 GGNBP2
 gametogenetin binding protein 2
chr4_-_111119804 0.26 ENST00000394607.3
ENST00000302274.3
 ELOVL6
 ELOVL fatty acid elongase 6
chr2_-_89545079 0.25 ENST00000468494.1
 IGKV2-30
 immunoglobulin kappa variable 2-30
chr15_-_34628951 0.25 ENST00000397707.2
ENST00000560611.1
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr3_+_186435065 0.25 ENST00000287611.2
ENST00000265023.4
 KNG1
 kininogen 1
chr6_+_36238237 0.25 ENST00000457797.1
ENST00000394571.2
 PNPLA1
 patatin-like phospholipase domain containing 1
chr11_-_72504637 0.24 ENST00000536377.1
ENST00000359373.5
 STARD10
ARAP1
 StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_+_36152091 0.21 ENST00000274254.5
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr14_-_80677815 0.20 ENST00000557125.1
ENST00000555750.1
 DIO2
 deiodinase, iodothyronine, type II
chr8_+_38585704 0.20 ENST00000519416.1
ENST00000520615.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr11_-_5248294 0.20 ENST00000335295.4
 HBB
 hemoglobin, beta
chr1_+_154377669 0.20 ENST00000368485.3
ENST00000344086.4
 IL6R
 interleukin 6 receptor
chr2_-_183291741 0.18 ENST00000351439.5
ENST00000409365.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr12_-_13248598 0.17 ENST00000337630.6
ENST00000545699.1
 GSG1
 germ cell associated 1
chr2_+_226265364 0.16 ENST00000272907.6
 NYAP2
 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr11_+_60048053 0.15 ENST00000337908.4
 MS4A4A
 membrane-spanning 4-domains, subfamily A, member 4A
chr12_-_114841703 0.14 ENST00000526441.1
 TBX5
 T-box 5
chr12_-_13248562 0.14 ENST00000457134.2
ENST00000537302.1
 GSG1
 germ cell associated 1
chrX_-_73512177 0.14 ENST00000603672.1
ENST00000418855.1
 FTX
 FTX transcript, XIST regulator (non-protein coding)
chr14_-_50319758 0.14 ENST00000298310.5
 NEMF
 nuclear export mediator factor
chr1_+_165864821 0.14 ENST00000470820.1
 UCK2
 uridine-cytidine kinase 2
chr17_+_61851504 0.13 ENST00000359353.5
ENST00000389924.2
 DDX42
 DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr14_+_96000930 0.13 ENST00000331334.4
 GLRX5
 glutaredoxin 5
chr2_-_32390801 0.12 ENST00000608489.1
 RP11-563N4.1
 RP11-563N4.1
chr16_+_6069586 0.11 ENST00000547372.1
 RBFOX1
 RNA binding protein, fox-1 homolog (C. elegans) 1
chr14_+_96722539 0.10 ENST00000553356.1
 BDKRB1
 bradykinin receptor B1
chr5_-_145562147 0.09 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
 LARS
 leucyl-tRNA synthetase
chr11_+_59824127 0.09 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr4_+_71248795 0.09 ENST00000304915.3
 SMR3B
 submaxillary gland androgen regulated protein 3B
chr17_+_61851157 0.08 ENST00000578681.1
ENST00000583590.1
 DDX42
 DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr1_+_172389821 0.08 ENST00000367727.4
 C1orf105
 chromosome 1 open reading frame 105
chr4_+_71600144 0.08 ENST00000502653.1
 RUFY3
 RUN and FYVE domain containing 3
chr11_+_59824060 0.07 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr5_-_146258205 0.06 ENST00000394413.3
 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
chr1_+_158901329 0.06 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
 PYHIN1
 pyrin and HIN domain family, member 1
chr5_+_36152179 0.06 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr16_+_6069072 0.06 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
 RBFOX1
 RNA binding protein, fox-1 homolog (C. elegans) 1
chr19_+_55417530 0.05 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
 NCR1
 natural cytotoxicity triggering receptor 1
chr12_-_10605929 0.05 ENST00000347831.5
ENST00000359151.3
 KLRC1
 killer cell lectin-like receptor subfamily C, member 1
chr13_-_36788718 0.05 ENST00000317764.6
ENST00000379881.3
 SOHLH2
 spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr12_-_323689 0.04 ENST00000428720.1
 SLC6A12
 solute carrier family 6 (neurotransmitter transporter), member 12
chr11_+_60048129 0.04 ENST00000355131.3
 MS4A4A
 membrane-spanning 4-domains, subfamily A, member 4A
chr21_-_37852359 0.04 ENST00000399137.1
ENST00000399135.1
 CLDN14
 claudin 14
chr14_-_50319482 0.04 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
 NEMF
 nuclear export mediator factor
chr1_+_165864800 0.04 ENST00000469256.2
 UCK2
 uridine-cytidine kinase 2
chr8_+_42552533 0.03 ENST00000289957.2
 CHRNB3
 cholinergic receptor, nicotinic, beta 3 (neuronal)
chr19_-_36822595 0.03 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
 LINC00665
 long intergenic non-protein coding RNA 665
chr19_+_55417499 0.03 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
 NCR1
 natural cytotoxicity triggering receptor 1
chr14_-_80677970 0.01 ENST00000438257.4
 DIO2
 deiodinase, iodothyronine, type II
chr12_-_8693539 0.01 ENST00000299663.3
 CLEC4E
 C-type lectin domain family 4, member E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.6 4.7 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.2 3.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
1.1 8.6 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.8 2.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.7 2.2 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.6 4.3 GO:0006642 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269)
0.6 1.8 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.6 6.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 1.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5 1.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.5 3.4 GO:0008218 bioluminescence(GO:0008218)
0.4 2.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.4 3.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.4 2.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.7 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 5.2 GO:0030502 pinocytosis(GO:0006907) negative regulation of bone mineralization(GO:0030502)
0.2 3.8 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.2 1.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 4.2 GO:0006825 copper ion transport(GO:0006825)
0.1 0.7 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364) vitamin B6 metabolic process(GO:0042816)
0.1 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.4 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.5 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.9 GO:0071108 protein K63-linked deubiquitination(GO:0070536) protein K48-linked deubiquitination(GO:0071108)
0.0 1.0 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425) valyl-tRNA aminoacylation(GO:0006438)
0.0 1.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.7 GO:0098743 cell aggregation(GO:0098743)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.8 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0035473 lipase binding(GO:0035473)
0.9 3.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.7 3.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.6 2.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.5 4.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.8 GO:0016841 ammonia-lyase activity(GO:0016841)
0.4 2.5 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.3 1.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 4.7 GO:0015643 toxic substance binding(GO:0015643)
0.3 8.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.7 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 3.5 GO:0001848 complement binding(GO:0001848)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.9 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 4.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.0 2.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.5 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 13.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 4.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 4.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 4.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 3.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 3.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 6.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 5.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 5.2 PID BMP PATHWAY BMP receptor signaling
0.1 4.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 4.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 4.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 3.3 GO:0042627 chylomicron(GO:0042627)
0.2 20.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 14.7 GO:0072562 blood microparticle(GO:0072562)
0.0 3.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0005802 trans-Golgi network(GO:0005802)