ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CPEB1 Links Ensembl NCBI GeneCards UniProt	ENSG00000214575.5	CPEB1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CPEB1	hg19_v2_chr15_-_83316087_83316137	0.45	8.1e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr2_-_151344172	7.05	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3	Rho family GTPase 3
chr2_-_190044480	4.49	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr14_-_75079026	4.26	ENST00000261978.4	LTBP2	latent transforming growth factor beta binding protein 2
chr7_+_100464760	3.57	ENST00000200457.4	TRIP6	thyroid hormone receptor interactor 6
chrX_+_135278908	3.27	ENST00000539015.1 ENST00000370683.1	FHL1	four and a half LIM domains 1
chr10_+_17271266	3.11	ENST00000224237.5	VIM	vimentin
chrX_+_135279179	2.88	ENST00000370676.3	FHL1	four and a half LIM domains 1
chr3_+_158991025	2.81	ENST00000337808.6	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chrX_+_100805496	2.49	ENST00000372829.3	ARMCX1	armadillo repeat containing, X-linked 1
chr2_-_175711133	2.45	ENST00000409597.1 ENST00000413882.1	CHN1	chimerin 1
chr7_-_27205136	2.38	ENST00000396345.1 ENST00000343483.6	HOXA9	homeobox A9
chr4_+_174089904	2.28	ENST00000265000.4	GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr17_+_45286706	2.21	ENST00000393450.1 ENST00000572303.1	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr3_+_159570722	2.14	ENST00000482804.1	SCHIP1	schwannomin interacting protein 1
chrX_-_3264682	2.01	ENST00000217939.6	MXRA5	matrix-remodelling associated 5
chr11_+_35160709	1.88	ENST00000415148.2 ENST00000433354.2 ENST00000449691.2 ENST00000437706.2 ENST00000360158.4 ENST00000428726.2 ENST00000526669.2 ENST00000433892.2 ENST00000278386.6 ENST00000434472.2 ENST00000352818.4 ENST00000442151.2	CD44	CD44 molecule (Indian blood group)
chr12_-_52967600	1.86	ENST00000549343.1 ENST00000305620.2	KRT74	keratin 74
chr3_+_158787041	1.85	ENST00000471575.1 ENST00000476809.1 ENST00000485419.1	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr17_+_45286387	1.83	ENST00000572316.1 ENST00000354968.1 ENST00000576874.1 ENST00000536623.2	MYL4	myosin, light chain 4, alkali; atrial, embryonic
chr8_+_70378852	1.81	ENST00000525061.1 ENST00000458141.2 ENST00000260128.4	SULF1	sulfatase 1
chr2_-_190927447	1.80	ENST00000260950.4	MSTN	myostatin
chr18_-_53177984	1.78	ENST00000543082.1	TCF4	transcription factor 4
chr18_-_52989217	1.78	ENST00000570287.2	TCF4	transcription factor 4
chr7_+_134551583	1.69	ENST00000435928.1	CALD1	caldesmon 1
chr10_-_126847276	1.67	ENST00000531469.1	CTBP2	C-terminal binding protein 2
chr18_+_61554932	1.67	ENST00000299502.4 ENST00000457692.1 ENST00000413956.1	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr12_-_52845910	1.65	ENST00000252252.3	KRT6B	keratin 6B
chr12_-_91539918	1.64	ENST00000548218.1	DCN	decorin
chr12_+_54422142	1.62	ENST00000243108.4	HOXC6	homeobox C6
chr12_-_50616382	1.60	ENST00000552783.1	LIMA1	LIM domain and actin binding 1
chr6_-_41909191	1.56	ENST00000512426.1 ENST00000372987.4	CCND3	cyclin D3
chr18_-_53070913	1.54	ENST00000568186.1 ENST00000564228.1	TCF4	transcription factor 4
chr11_-_27723158	1.51	ENST00000395980.2	BDNF	brain-derived neurotrophic factor
chr8_-_108510224	1.51	ENST00000517746.1 ENST00000297450.3	ANGPT1	angiopoietin 1
chr11_-_5276008	1.51	ENST00000336906.4	HBG2	hemoglobin, gamma G
chr1_+_209848749	1.47	ENST00000367029.4	G0S2	G0/G1switch 2
chr12_+_4385230	1.36	ENST00000536537.1	CCND2	cyclin D2
chr5_+_36608422	1.36	ENST00000381918.3	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_145277640	1.35	ENST00000539609.3	ZEB2	zinc finger E-box binding homeobox 2
chr12_-_91546926	1.32	ENST00000550758.1	DCN	decorin
chr2_-_145277569	1.31	ENST00000303660.4	ZEB2	zinc finger E-box binding homeobox 2
chr12_-_91572278	1.28	ENST00000425043.1 ENST00000420120.2 ENST00000441303.2 ENST00000456569.2	DCN	decorin
chr15_-_60690163	1.27	ENST00000558998.1 ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2	ANXA2	annexin A2
chr3_+_69928256	1.24	ENST00000394355.2	MITF	microphthalmia-associated transcription factor
chr18_-_53253112	1.21	ENST00000568673.1 ENST00000562847.1 ENST00000568147.1	TCF4	transcription factor 4
chr18_-_53253323	1.20	ENST00000540999.1 ENST00000563888.2	TCF4	transcription factor 4
chr2_+_170366203	1.15	ENST00000284669.1	KLHL41	kelch-like family member 41
chr1_-_103574024	1.12	ENST00000512756.1 ENST00000370096.3 ENST00000358392.2 ENST00000353414.4	COL11A1	collagen, type XI, alpha 1
chr6_-_27114577	1.10	ENST00000356950.1 ENST00000396891.4	HIST1H2BK	histone cluster 1, H2bk
chr13_+_102142296	1.08	ENST00000376162.3	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr4_-_111563076	1.07	ENST00000354925.2 ENST00000511990.1	PITX2	paired-like homeodomain 2
chr8_+_77593474	1.04	ENST00000455469.2 ENST00000050961.6	ZFHX4	zinc finger homeobox 4
chr10_-_104262460	1.02	ENST00000446605.2 ENST00000369905.4 ENST00000545684.1	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr13_+_73632897	1.02	ENST00000377687.4	KLF5	Kruppel-like factor 5 (intestinal)
chr10_-_104262426	1.02	ENST00000487599.1	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr13_-_67802549	1.02	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr2_+_173292390	0.98	ENST00000442250.1 ENST00000458358.1 ENST00000409080.1	ITGA6	integrin, alpha 6
chr3_+_99357319	0.97	ENST00000452013.1 ENST00000261037.3 ENST00000273342.4	COL8A1	collagen, type VIII, alpha 1
chr12_+_79258547	0.94	ENST00000457153.2	SYT1	synaptotagmin I
chrX_-_48931648	0.94	ENST00000376386.3 ENST00000376390.4	PRAF2	PRA1 domain family, member 2
chr3_-_141747439	0.93	ENST00000467667.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_173292280	0.92	ENST00000264107.7	ITGA6	integrin, alpha 6
chr2_-_211168332	0.92	ENST00000341685.4	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr12_+_79258444	0.92	ENST00000261205.4	SYT1	synaptotagmin I
chr5_+_32788945	0.91	ENST00000326958.1	AC026703.1	AC026703.1
chr4_+_74347400	0.88	ENST00000226355.3	AFM	afamin
chr17_+_32582293	0.88	ENST00000580907.1 ENST00000225831.4	CCL2	chemokine (C-C motif) ligand 2
chr15_-_56209306	0.87	ENST00000506154.1 ENST00000338963.2 ENST00000508342.1	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr3_+_69788576	0.85	ENST00000352241.4 ENST00000448226.2	MITF	microphthalmia-associated transcription factor
chr22_+_29876197	0.85	ENST00000310624.6	NEFH	neurofilament, heavy polypeptide
chr11_+_12766583	0.84	ENST00000361985.2	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_-_52904425	0.84	ENST00000535450.1	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chrX_-_114252193	0.84	ENST00000243213.1	IL13RA2	interleukin 13 receptor, alpha 2
chr11_-_8832182	0.84	ENST00000527510.1 ENST00000528527.1 ENST00000528523.1 ENST00000313726.6	ST5	suppression of tumorigenicity 5
chr11_+_69924397	0.83	ENST00000355303.5	ANO1	anoctamin 1, calcium activated chloride channel
chr1_+_84630645	0.83	ENST00000394839.2	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr18_-_33702078	0.83	ENST00000586829.1	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chr1_+_164528866	0.83	ENST00000420696.2	PBX1	pre-B-cell leukemia homeobox 1
chr6_+_12290586	0.80	ENST00000379375.5	EDN1	endothelin 1
chr3_-_18480260	0.80	ENST00000454909.2	SATB1	SATB homeobox 1
chr3_+_101546827	0.79	ENST00000461724.1 ENST00000483180.1 ENST00000394054.2	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_116311402	0.78	ENST00000261448.5	CASQ2	calsequestrin 2 (cardiac muscle)
chr9_-_21995300	0.78	ENST00000498628.2	CDKN2A	cyclin-dependent kinase inhibitor 2A
chr9_-_16870704	0.77	ENST00000380672.4 ENST00000380667.2 ENST00000380666.2 ENST00000486514.1	BNC2	basonuclin 2
chr1_+_163039143	0.76	ENST00000531057.1 ENST00000527809.1 ENST00000367908.4	RGS4	regulator of G-protein signaling 4
chr11_-_9025541	0.76	ENST00000525100.1 ENST00000309166.3 ENST00000531090.1	NRIP3	nuclear receptor interacting protein 3
chr8_+_77593448	0.75	ENST00000521891.2	ZFHX4	zinc finger homeobox 4
chr7_-_83824169	0.75	ENST00000265362.4	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_69924639	0.74	ENST00000538023.1 ENST00000398543.2	ANO1	anoctamin 1, calcium activated chloride channel
chr18_-_52989525	0.74	ENST00000457482.3	TCF4	transcription factor 4
chr4_+_74735102	0.73	ENST00000395761.3	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr6_-_46293378	0.73	ENST00000330430.6	RCAN2	regulator of calcineurin 2
chr1_-_201391149	0.72	ENST00000555948.1 ENST00000556362.1	TNNI1	troponin I type 1 (skeletal, slow)
chr9_-_21995249	0.72	ENST00000494262.1	CDKN2A	cyclin-dependent kinase inhibitor 2A
chr1_-_200379180	0.72	ENST00000294740.3	ZNF281	zinc finger protein 281
chr1_-_156675368	0.71	ENST00000368222.3	CRABP2	cellular retinoic acid binding protein 2
chr12_-_49412588	0.70	ENST00000547082.1 ENST00000395170.3	PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr1_+_84630053	0.70	ENST00000394838.2 ENST00000370682.3 ENST00000432111.1	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr17_-_39553844	0.69	ENST00000251645.2	KRT31	keratin 31
chr3_-_37216055	0.69	ENST00000336686.4	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2
chr12_-_49412541	0.69	ENST00000547306.1 ENST00000548857.1 ENST00000551696.1 ENST00000316299.5	PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr18_+_34124507	0.69	ENST00000591635.1	FHOD3	formin homology 2 domain containing 3
chr11_+_20385666	0.67	ENST00000532081.1 ENST00000531058.1	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr3_-_196910721	0.66	ENST00000443183.1	DLG1	discs, large homolog 1 (Drosophila)
chr3_-_196911002	0.66	ENST00000452595.1	DLG1	discs, large homolog 1 (Drosophila)
chr12_-_71148413	0.66	ENST00000440835.2 ENST00000549308.1 ENST00000550661.1	PTPRR	protein tyrosine phosphatase, receptor type, R
chr9_-_23825956	0.65	ENST00000397312.2	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr1_-_201390846	0.65	ENST00000367312.1 ENST00000555340.2 ENST00000361379.4	TNNI1	troponin I type 1 (skeletal, slow)
chr7_-_81399438	0.65	ENST00000222390.5	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399329	0.64	ENST00000453411.1 ENST00000444829.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_27100811	0.64	ENST00000359193.2	HIST1H2AG	histone cluster 1, H2ag
chr6_+_39760783	0.64	ENST00000398904.2 ENST00000538976.1	DAAM2	dishevelled associated activator of morphogenesis 2
chr4_-_102268484	0.64	ENST00000394853.4	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr18_+_29027696	0.64	ENST00000257189.4	DSG3	desmoglein 3
chr2_-_55277654	0.63	ENST00000337526.6 ENST00000317610.7 ENST00000357732.4	RTN4	reticulon 4
chr14_-_61748550	0.62	ENST00000555868.1	TMEM30B	transmembrane protein 30B
chr9_+_82186872	0.62	ENST00000376544.3 ENST00000376520.4	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_+_73442487	0.62	ENST00000380575.4 ENST00000380584.4 ENST00000458204.1 ENST00000357036.5 ENST00000417091.1 ENST00000429192.1 ENST00000442310.1 ENST00000380553.4 ENST00000380576.5 ENST00000428787.1 ENST00000320399.6	ELN	elastin
chr4_-_102268628	0.61	ENST00000323055.6 ENST00000512215.1 ENST00000394854.3	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_73442422	0.61	ENST00000358929.4 ENST00000431562.1 ENST00000320492.7 ENST00000438906.1	ELN	elastin
chr11_-_102651343	0.60	ENST00000279441.4 ENST00000539681.1	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr10_-_105845674	0.60	ENST00000353479.5 ENST00000369733.3	COL17A1	collagen, type XVII, alpha 1
chr12_-_52828147	0.59	ENST00000252245.5	KRT75	keratin 75
chr4_-_111119804	0.59	ENST00000394607.3 ENST00000302274.3	ELOVL6	ELOVL fatty acid elongase 6
chrX_-_15619076	0.58	ENST00000252519.3	ACE2	angiotensin I converting enzyme 2
chr11_+_34642656	0.58	ENST00000257831.3 ENST00000450654.2	EHF	ets homologous factor
chr6_-_31697977	0.57	ENST00000375787.2	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr9_-_13165457	0.56	ENST00000542239.1 ENST00000538841.1 ENST00000433359.2	MPDZ	multiple PDZ domain protein
chr2_+_88047606	0.56	ENST00000359481.4	PLGLB2	plasminogen-like B2
chr17_-_10560619	0.56	ENST00000583535.1	MYH3	myosin, heavy chain 3, skeletal muscle, embryonic
chrX_-_77395186	0.55	ENST00000341864.5	TAF9B	TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr12_-_49412525	0.55	ENST00000551121.1 ENST00000552212.1 ENST00000548605.1 ENST00000548950.1 ENST00000547125.1	PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr7_-_27219849	0.55	ENST00000396344.4	HOXA10	homeobox A10
chr11_-_57194948	0.53	ENST00000533235.1 ENST00000526621.1 ENST00000352187.1	SLC43A3	solute carrier family 43, member 3
chr12_-_118797475	0.53	ENST00000541786.1 ENST00000419821.2 ENST00000541878.1	TAOK3	TAO kinase 3
chr3_-_141747459	0.52	ENST00000477292.1 ENST00000478006.1 ENST00000495310.1 ENST00000486111.1	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chrX_+_38211777	0.52	ENST00000039007.4	OTC	ornithine carbamoyltransferase
chr7_-_50860565	0.51	ENST00000403097.1	GRB10	growth factor receptor-bound protein 10
chr10_-_62493223	0.51	ENST00000373827.2	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chrX_+_106871713	0.51	ENST00000372435.4 ENST00000372428.4 ENST00000372419.3 ENST00000543248.1	PRPS1	phosphoribosyl pyrophosphate synthetase 1
chr3_+_44690211	0.51	ENST00000396056.2 ENST00000432115.2 ENST00000415571.2 ENST00000399560.2 ENST00000296092.3 ENST00000542250.1 ENST00000453164.1	ZNF35	zinc finger protein 35
chr4_-_102267953	0.51	ENST00000523694.2 ENST00000507176.1	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr22_+_41258250	0.51	ENST00000544094.1	XPNPEP3	X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr9_+_116263778	0.50	ENST00000394646.3	RGS3	regulator of G-protein signaling 3
chr6_-_27100529	0.50	ENST00000607124.1 ENST00000339812.2 ENST00000541790.1	HIST1H2BJ	histone cluster 1, H2bj
chr7_+_73442457	0.50	ENST00000438880.1 ENST00000414324.1 ENST00000380562.4	ELN	elastin
chr5_+_140071178	0.50	ENST00000508522.1 ENST00000448069.2	HARS2	histidyl-tRNA synthetase 2, mitochondrial
chr17_-_39538550	0.49	ENST00000394001.1	KRT34	keratin 34
chr12_+_28410128	0.49	ENST00000381259.1 ENST00000381256.1	CCDC91	coiled-coil domain containing 91
chr8_+_85095553	0.49	ENST00000521268.1	RALYL	RALY RNA binding protein-like
chr18_+_47088401	0.49	ENST00000261292.4 ENST00000427224.2 ENST00000580036.1	LIPG	lipase, endothelial
chr12_+_14518598	0.48	ENST00000261168.4 ENST00000538511.1 ENST00000545723.1 ENST00000543189.1 ENST00000536444.1	ATF7IP	activating transcription factor 7 interacting protein
chr4_-_74904398	0.48	ENST00000296026.4	CXCL3	chemokine (C-X-C motif) ligand 3
chr11_-_62473706	0.47	ENST00000403550.1	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_-_10452929	0.47	ENST00000532183.2 ENST00000397183.2 ENST00000420805.1	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr1_-_152297679	0.46	ENST00000368799.1	FLG	filaggrin
chr1_+_26798955	0.46	ENST00000361427.5	HMGN2	high mobility group nucleosomal binding domain 2
chr5_-_82969405	0.46	ENST00000510978.1	HAPLN1	hyaluronan and proteoglycan link protein 1
chr11_-_62473776	0.45	ENST00000278893.7 ENST00000407022.3 ENST00000421906.1	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_21927736	0.45	ENST00000240662.2	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8
chr8_-_86253888	0.45	ENST00000522389.1 ENST00000432364.2 ENST00000517618.1	CA1	carbonic anhydrase I
chr1_-_200379129	0.44	ENST00000367353.1	ZNF281	zinc finger protein 281
chr13_-_103719196	0.44	ENST00000245312.3	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr8_-_61193947	0.43	ENST00000317995.4	CA8	carbonic anhydrase VIII
chr14_-_92413353	0.43	ENST00000556154.1	FBLN5	fibulin 5
chr9_-_23826298	0.43	ENST00000380117.1	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr8_-_93029865	0.43	ENST00000422361.2	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_22040620	0.42	ENST00000426880.2	HRH4	histamine receptor H4
chr7_-_81399411	0.42	ENST00000423064.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr8_+_9953061	0.42	ENST00000522907.1 ENST00000528246.1	MSRA	methionine sulfoxide reductase A
chr8_-_95274536	0.41	ENST00000297596.2 ENST00000396194.2	GEM	GTP binding protein overexpressed in skeletal muscle
chr1_-_156675535	0.41	ENST00000368221.1	CRABP2	cellular retinoic acid binding protein 2
chr8_+_104831472	0.41	ENST00000262231.10 ENST00000507740.1	RIMS2	regulating synaptic membrane exocytosis 2
chr8_+_104892639	0.41	ENST00000436393.2	RIMS2	regulating synaptic membrane exocytosis 2
chr17_-_4852332	0.41	ENST00000572383.1	PFN1	profilin 1
chr4_-_48782259	0.40	ENST00000507711.1 ENST00000358350.4 ENST00000537810.1 ENST00000264319.7	FRYL	FRY-like
chr18_+_3252206	0.39	ENST00000578562.2	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_169757750	0.38	ENST00000375363.3 ENST00000429379.2 ENST00000421979.1	G6PC2	glucose-6-phosphatase, catalytic, 2
chr2_-_87248975	0.38	ENST00000409310.2 ENST00000355705.3	PLGLB1	plasminogen-like B1
chr5_+_162932554	0.38	ENST00000321757.6 ENST00000421814.2 ENST00000518095.1	MAT2B	methionine adenosyltransferase II, beta
chr11_+_1940925	0.38	ENST00000453458.1 ENST00000381557.2 ENST00000381589.3 ENST00000381579.3 ENST00000381563.4 ENST00000344578.4	TNNT3	troponin T type 3 (skeletal, fast)
chr18_+_3252265	0.37	ENST00000580887.1 ENST00000536605.1	MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric
chr6_-_161085291	0.37	ENST00000316300.5	LPA	lipoprotein, Lp(a)
chr8_+_9953214	0.37	ENST00000382490.5	MSRA	methionine sulfoxide reductase A
chr1_+_224301787	0.37	ENST00000366862.5 ENST00000424254.2	FBXO28	F-box protein 28
chr1_-_200379104	0.36	ENST00000367352.3	ZNF281	zinc finger protein 281
chr3_-_69129501	0.36	ENST00000540295.1 ENST00000415609.2 ENST00000361055.4 ENST00000349511.4	UBA3	ubiquitin-like modifier activating enzyme 3
chr5_-_140070897	0.36	ENST00000448240.1 ENST00000438307.2 ENST00000415192.2 ENST00000457527.2 ENST00000307633.3 ENST00000507746.1 ENST00000431330.2	HARS	histidyl-tRNA synthetase
chr21_-_36421626	0.35	ENST00000300305.3	RUNX1	runt-related transcription factor 1
chr5_+_135496675	0.35	ENST00000507637.1	SMAD5	SMAD family member 5
chr1_+_65730385	0.34	ENST00000263441.7 ENST00000395325.3	DNAJC6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_-_74864386	0.34	ENST00000296027.4	CXCL5	chemokine (C-X-C motif) ligand 5
chr7_+_73442102	0.34	ENST00000445912.1 ENST00000252034.7	ELN	elastin
chr11_+_112832202	0.33	ENST00000534015.1	NCAM1	neural cell adhesion molecule 1
chr20_+_31823792	0.33	ENST00000375413.4 ENST00000354297.4 ENST00000375422.2	BPIFA1	BPI fold containing family A, member 1
chr9_+_116263639	0.33	ENST00000343817.5	RGS3	regulator of G-protein signaling 3
chr21_-_36421535	0.33	ENST00000416754.1 ENST00000437180.1 ENST00000455571.1	RUNX1	runt-related transcription factor 1
chr6_-_49712123	0.33	ENST00000263045.4	CRISP3	cysteine-rich secretory protein 3
chr2_+_181845843	0.32	ENST00000602710.1	UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr7_-_14029283	0.32	ENST00000433547.1 ENST00000405192.2	ETV1	ets variant 1

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.5	GO:0005588	collagen type V trimer(GO:0005588)
0.7	3.6	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.6	1.9	GO:0034676	integrin alpha6-beta4 complex(GO:0034676)
0.4	1.9	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3	2.0	GO:0002177	manchette(GO:0002177)
0.3	4.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	1.9	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3	2.6	GO:0071953	elastic fiber(GO:0071953)
0.3	1.3	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.2	1.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.2	0.8	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.2	0.8	GO:0030314	junctional membrane complex(GO:0030314)
0.2	1.8	GO:0005955	calcineurin complex(GO:0005955)
0.2	0.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	0.5	GO:0005826	actomyosin contractile ring(GO:0005826)
0.2	0.5	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	1.5	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.7	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.5	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	0.4	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	1.1	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	1.7	GO:0005833	hemoglobin complex(GO:0005833)
0.1	1.7	GO:0030478	actin cap(GO:0030478)
0.1	1.3	GO:0097025	lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1	1.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	0.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	1.9	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	2.1	GO:0005861	troponin complex(GO:0005861)
0.1	3.7	GO:0045095	keratin filament(GO:0045095)
0.1	5.5	GO:0005882	intermediate filament(GO:0005882)
0.1	1.5	GO:0005859	muscle myosin complex(GO:0005859)
0.1	5.1	GO:0031672	A band(GO:0031672)
0.1	0.1	GO:0005916	fascia adherens(GO:0005916)
0.1	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.0	2.4	GO:0000786	nucleosome(GO:0000786)
0.0	0.6	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.6	GO:0000124	SAGA complex(GO:0000124)
0.0	0.9	GO:0030057	desmosome(GO:0030057)
0.0	1.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.6	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	1.6	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.5	GO:0000785	chromatin(GO:0000785)
0.0	0.7	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	1.9	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	1.9	GO:0005902	microvillus(GO:0005902)
0.0	0.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	1.6	GO:0005811	lipid particle(GO:0005811)
0.0	11.4	GO:0005925	focal adhesion(GO:0005925)
0.0	0.4	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.7	GO:0016459	myosin complex(GO:0016459)
0.0	2.6	GO:0032993	protein-DNA complex(GO:0032993)
0.0	5.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0060091	kinocilium(GO:0060091)
0.0	1.8	GO:0005795	Golgi stack(GO:0005795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.0	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.8	5.0	GO:1990254	keratin filament binding(GO:1990254)
0.6	8.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.5	1.5	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.5	1.8	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	1.9	GO:0030348	syntaxin-3 binding(GO:0030348)
0.3	1.6	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.3	0.9	GO:0004821	histidine-tRNA ligase activity(GO:0004821)
0.3	0.8	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.2	1.7	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2	0.9	GO:0008431	vitamin E binding(GO:0008431)
0.2	3.5	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	1.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	1.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	3.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	1.8	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	0.7	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.2	0.8	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	0.8	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2	2.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	0.5	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	1.9	GO:0038132	neuregulin binding(GO:0038132)
0.1	1.7	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.9	GO:0050815	phosphoserine binding(GO:0050815)
0.1	0.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	1.3	GO:0097016	L27 domain binding(GO:0097016)
0.1	0.6	GO:0016403	dimethylargininase activity(GO:0016403)
0.1	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.3	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	1.6	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.6	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	0.6	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.4	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.6	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	1.5	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	5.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	2.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.5	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	1.1	GO:0016918	retinal binding(GO:0016918)
0.1	5.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.7	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0080101	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	2.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.5	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	1.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.4	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	2.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	2.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	1.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.4	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	2.0	GO:0070888	E-box binding(GO:0070888)
0.0	0.8	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.3	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.6	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	2.2	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	6.6	GO:0008201	heparin binding(GO:0008201)
0.0	0.8	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0070915	lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	1.1	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	5.2	GO:0044325	ion channel binding(GO:0044325)
0.0	0.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.7	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.4	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	7.2	GO:0003924	GTPase activity(GO:0003924)
0.0	0.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	1.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.6	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.5	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0039706	co-receptor binding(GO:0039706)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.5	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.7	3.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.7	2.7	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.6	1.9	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.6	1.8	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.5	2.1	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.5	1.5	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.5	2.0	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4	0.8	GO:0086068	Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.4	1.1	GO:0060577	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.4	4.2	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3	0.3	GO:0044407	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.3	1.5	GO:0097338	response to clozapine(GO:0097338)
0.3	1.8	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.3	0.9	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
0.3	0.9	GO:0006427	histidyl-tRNA aminoacylation(GO:0006427)
0.3	3.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.3	0.8	GO:0048936	neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936)
0.3	0.8	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2	1.9	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	1.1	GO:0035989	tendon development(GO:0035989)
0.2	1.8	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	1.5	GO:0048014	Tie signaling pathway(GO:0048014)
0.2	2.4	GO:0042118	endothelial cell activation(GO:0042118)
0.2	1.4	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2	1.3	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2	1.7	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2	1.6	GO:0015705	iodide transport(GO:0015705)
0.2	0.5	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.2	0.6	GO:0072660	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	1.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.4	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	1.5	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.1	1.9	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.1	0.5	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.7	GO:0021828	cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1	1.4	GO:0014883	transition between fast and slow fiber(GO:0014883)
0.1	0.5	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.4	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	0.6	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.1	1.7	GO:0015671	oxygen transport(GO:0015671)
0.1	1.0	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	1.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.7	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	4.0	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.1	6.0	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.1	1.4	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.1	0.6	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	1.8	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.8	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.1	1.6	GO:0007398	ectoderm development(GO:0007398)
0.1	0.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.8	GO:0030091	protein repair(GO:0030091)
0.1	2.4	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	0.2	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.1	0.7	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	1.7	GO:0010172	embryonic body morphogenesis(GO:0010172)
0.1	4.3	GO:0097435	fibril organization(GO:0097435)
0.1	0.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.8	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.1	0.6	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.3	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.6	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.6	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.3	GO:0015862	uridine transport(GO:0015862)
0.1	0.3	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.1	0.1	GO:0007521	muscle cell fate determination(GO:0007521)
0.1	0.3	GO:1904783	positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.0	1.6	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.6	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0	2.0	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	2.0	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	1.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	1.4	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.5	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.7	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	1.0	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.0	0.5	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	2.3	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.7	GO:0043586	tongue development(GO:0043586)
0.0	0.9	GO:0034389	lipid particle organization(GO:0034389)
0.0	1.9	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.5	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0001554	luteolysis(GO:0001554)
0.0	0.2	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.0	0.9	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.5	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.7	GO:0030837	negative regulation of actin filament polymerization(GO:0030837)
0.0	0.1	GO:0030222	eosinophil differentiation(GO:0030222)
0.0	0.5	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.1	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0	1.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.5	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.0	0.2	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	1.5	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	8.1	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.1	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119) mRNA pseudouridine synthesis(GO:1990481)
0.0	0.1	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	1.5	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.3	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	1.7	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.5	GO:0003094	glomerular filtration(GO:0003094)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	1.5	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.7	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.2	GO:0070933	histone H4 deacetylation(GO:0070933)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.4	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	0.8	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.9	GO:0051180	vitamin transport(GO:0051180)
0.0	1.9	GO:0070268	cornification(GO:0070268)
0.0	1.9	GO:0006110	regulation of glycolytic process(GO:0006110)
0.0	0.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	2.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.2	GO:0034390	smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0	1.0	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.8	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
0.0	0.8	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.4	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.8	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0019050	suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.1	GO:0021546	rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:0010863	positive regulation of phospholipase C activity(GO:0010863)
0.0	0.1	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	5.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	2.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	8.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	1.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.9	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	2.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	3.1	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.9	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	1.8	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	9.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	3.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	1.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	2.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	2.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	2.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.8	PID ENDOTHELIN PATHWAY	Endothelins
0.0	1.5	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.6	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.4	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	3.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.1	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	8.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	9.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.9	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	6.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.9	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	1.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.1	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	4.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	2.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	1.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	1.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.5	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	2.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.7	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	2.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.2	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	1.2	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	1.1	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.4	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors