Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for DLX5

Z-value: 0.57

Motif logo

logo of

Transcription factors associated with DLX5

Gene Symbol Gene ID Gene Info
DLX5
ENSG00000105880.4 DLX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX5hg19_v2_chr7_-_96654133_966544090.058.4e-01Click!

Activity profile of DLX5 motif

Sorted Z-values of DLX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_81110684 2.00 ENST00000228644.3
 MYF5
 myogenic factor 5
chr4_-_143767428 1.40 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
chr7_+_100770328 1.12 ENST00000223095.4
ENST00000445463.2
 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr12_+_54378923 1.09 ENST00000303460.4
 HOXC10
 homeobox C10
chr12_-_50616382 0.82 ENST00000552783.1
 LIMA1
 LIM domain and actin binding 1
chr8_+_32579341 0.72 ENST00000519240.1
ENST00000539990.1
 NRG1
 neuregulin 1
chr6_-_112194484 0.48 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
 FYN
 FYN oncogene related to SRC, FGR, YES
chr2_+_30369859 0.48 ENST00000402003.3
 YPEL5
 yippee-like 5 (Drosophila)
chr2_+_30369807 0.47 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
 YPEL5
 yippee-like 5 (Drosophila)
chr11_-_102651343 0.42 ENST00000279441.4
ENST00000539681.1
 MMP10
 matrix metallopeptidase 10 (stromelysin 2)
chr1_-_28969517 0.39 ENST00000263974.4
ENST00000373824.4
 TAF12
 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr18_-_33709268 0.39 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
 SLC39A6
 solute carrier family 39 (zinc transporter), member 6
chr2_-_220118631 0.38 ENST00000248437.4
 TUBA4A
 tubulin, alpha 4a
chr19_+_36606354 0.32 ENST00000589996.1
ENST00000591296.1
 TBCB
 tubulin folding cofactor B
chr19_+_36605850 0.31 ENST00000221855.3
 TBCB
 tubulin folding cofactor B
chr15_+_89631381 0.29 ENST00000352732.5
 ABHD2
 abhydrolase domain containing 2
chr11_-_26743546 0.28 ENST00000280467.6
ENST00000396005.3
 SLC5A12
 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr14_-_68283291 0.26 ENST00000555452.1
ENST00000347230.4
 ZFYVE26
 zinc finger, FYVE domain containing 26
chr14_-_24711470 0.23 ENST00000559969.1
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr12_+_7014126 0.20 ENST00000415834.1
ENST00000436789.1
 LRRC23
 leucine rich repeat containing 23
chr3_-_105588231 0.19 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_7013897 0.19 ENST00000007969.8
ENST00000323702.5
 LRRC23
 leucine rich repeat containing 23
chr12_-_10151773 0.19 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr14_-_24711865 0.19 ENST00000399423.4
ENST00000267415.7
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_24711806 0.18 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_202317815 0.18 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
chr11_-_71823715 0.17 ENST00000545944.1
ENST00000502597.2
 ANAPC15
 anaphase promoting complex subunit 15
chr11_-_71823266 0.16 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
 ANAPC15
 anaphase promoting complex subunit 15
chr12_+_7014064 0.16 ENST00000443597.2
 LRRC23
 leucine rich repeat containing 23
chr1_-_23670817 0.13 ENST00000478691.1
 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
chr1_-_23670813 0.11 ENST00000374612.1
 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
chr19_-_14785674 0.10 ENST00000253673.5
 EMR3
 egf-like module containing, mucin-like, hormone receptor-like 3
chr19_+_58570605 0.10 ENST00000359978.6
ENST00000401053.4
ENST00000439855.2
ENST00000313434.5
ENST00000511556.1
ENST00000506786.1
 ZNF135
 zinc finger protein 135
chr3_-_105587879 0.10 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr19_-_14785622 0.09 ENST00000443157.2
 EMR3
 egf-like module containing, mucin-like, hormone receptor-like 3
chr19_-_14785698 0.09 ENST00000344373.4
ENST00000595472.1
 EMR3
 egf-like module containing, mucin-like, hormone receptor-like 3
chr2_-_183387064 0.09 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr4_-_8873531 0.08 ENST00000400677.3
 HMX1
 H6 family homeobox 1
chr1_-_23670752 0.08 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
chr20_+_43849941 0.08 ENST00000372769.3
 SEMG2
 semenogelin II
chr8_-_22526597 0.08 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
 BIN3
 bridging integrator 3
chr6_-_38670897 0.08 ENST00000373365.4
 GLO1
 glyoxalase I
chr7_+_97736197 0.08 ENST00000297293.5
 LMTK2
 lemur tyrosine kinase 2
chr12_-_57039739 0.07 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
 ATP5B
 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr17_-_37009882 0.06 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
 RPL23
 ribosomal protein L23
chr9_+_34646651 0.05 ENST00000378842.3
 GALT
 galactose-1-phosphate uridylyltransferase
chr1_+_101003687 0.04 ENST00000315033.4
 GPR88
 G protein-coupled receptor 88
chr12_-_53171128 0.04 ENST00000332411.2
 KRT76
 keratin 76
chr7_-_86849883 0.04 ENST00000433078.1
 TMEM243
 transmembrane protein 243, mitochondrial
chr9_+_34646624 0.04 ENST00000450095.2
ENST00000556278.1
 GALT
GALT
 galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr14_+_24540046 0.04 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
 CPNE6
 copine VI (neuronal)
chr2_-_183387283 0.03 ENST00000435564.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr4_-_7069760 0.03 ENST00000264954.4
 GRPEL1
 GrpE-like 1, mitochondrial (E. coli)
chr4_+_151503077 0.03 ENST00000317605.4
 MAB21L2
 mab-21-like 2 (C. elegans)
chr3_+_11178779 0.03 ENST00000438284.2
 HRH1
 histamine receptor H1
chr1_-_78444738 0.02 ENST00000436586.2
ENST00000370768.2
 FUBP1
 far upstream element (FUSE) binding protein 1
chr17_-_47785504 0.02 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
 SLC35B1
 solute carrier family 35, member B1
chr1_+_50569575 0.02 ENST00000371827.1
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr1_+_160160283 0.02 ENST00000368079.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr7_-_99716952 0.02 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
 TAF6
 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr3_+_158519654 0.02 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr14_+_96000930 0.01 ENST00000331334.4
 GLRX5
 glutaredoxin 5
chr13_-_36050819 0.01 ENST00000379919.4
 MAB21L1
 mab-21-like 1 (C. elegans)
chr1_+_160160346 0.01 ENST00000368078.3
 CASQ1
 calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_54569968 0.01 ENST00000391366.1
 AL161915.1
 Uncharacterized protein
chr2_+_169757750 0.00 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
 G6PC2
 glucose-6-phosphatase, catalytic, 2
chr5_-_160279207 0.00 ENST00000327245.5
 ATP10B
 ATPase, class V, type 10B
chr19_+_54641444 0.00 ENST00000221232.5
ENST00000358389.3
 CNOT3
 CCR4-NOT transcription complex, subunit 3

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.6 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.0 GO:0061743 motor learning(GO:0061743)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.6 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)