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ENCODE cell lines, expression (Ernst 2011)

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Results for DMBX1

Z-value: 0.50

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Transcription factors associated with DMBX1

Gene Symbol Gene ID Gene Info
DMBX1
ENSG00000197587.6 DMBX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_46972669-0.126.6e-01Click!

Activity profile of DMBX1 motif

Sorted Z-values of DMBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DMBX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_169552748 2.06 ENST00000504519.1
ENST00000512127.1
 PALLD
 palladin, cytoskeletal associated protein
chr3_-_16524357 1.16 ENST00000432519.1
 RFTN1
 raftlin, lipid raft linker 1
chr9_-_21995300 1.15 ENST00000498628.2
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr2_-_175711133 1.00 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr6_+_89791507 0.97 ENST00000354922.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr9_-_21994344 0.94 ENST00000530628.2
ENST00000361570.3
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr12_+_53693812 0.94 ENST00000549488.1
 C12orf10
 chromosome 12 open reading frame 10
chr9_-_21995249 0.88 ENST00000494262.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr9_-_21994597 0.78 ENST00000579755.1
 CDKN2A
 cyclin-dependent kinase inhibitor 2A
chr3_-_121468513 0.75 ENST00000494517.1
ENST00000393667.3
 GOLGB1
 golgin B1
chr3_-_121468602 0.68 ENST00000340645.5
 GOLGB1
 golgin B1
chr19_+_41284121 0.68 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B
 RAB4B, member RAS oncogene family
chrX_-_48931648 0.67 ENST00000376386.3
ENST00000376390.4
 PRAF2
 PRA1 domain family, member 2
chr3_-_11685345 0.43 ENST00000430365.2
 VGLL4
 vestigial like 4 (Drosophila)
chr15_-_85201779 0.34 ENST00000360476.3
ENST00000394588.3
 NMB
 neuromedin B
chr2_+_223725652 0.34 ENST00000357430.3
ENST00000392066.3
 ACSL3
 acyl-CoA synthetase long-chain family member 3
chr18_+_29027696 0.33 ENST00000257189.4
 DSG3
 desmoglein 3
chr2_+_37571845 0.31 ENST00000537448.1
 QPCT
 glutaminyl-peptide cyclotransferase
chr14_+_50234309 0.30 ENST00000298307.5
 KLHDC2
 kelch domain containing 2
chr6_-_111927062 0.28 ENST00000359831.4
 TRAF3IP2
 TRAF3 interacting protein 2
chr3_-_149293990 0.23 ENST00000472417.1
 WWTR1
 WW domain containing transcription regulator 1
chr10_-_35104185 0.20 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
 PARD3
 par-3 family cell polarity regulator
chr8_-_110656995 0.14 ENST00000276646.9
ENST00000533065.1
 SYBU
 syntabulin (syntaxin-interacting)
chr10_+_74451883 0.13 ENST00000373053.3
ENST00000357157.6
 MCU
 mitochondrial calcium uniporter
chr1_-_94586651 0.12 ENST00000535735.1
ENST00000370225.3
 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
chr15_-_61521495 0.11 ENST00000335670.6
 RORA
 RAR-related orphan receptor A
chr3_-_150920979 0.11 ENST00000309180.5
ENST00000480322.1
 GPR171
 G protein-coupled receptor 171
chr12_+_54718904 0.09 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1
 coatomer protein complex, subunit zeta 1
chr1_+_109756523 0.09 ENST00000234677.2
ENST00000369923.4
 SARS
 seryl-tRNA synthetase
chr5_+_50678921 0.08 ENST00000230658.7
 ISL1
 ISL LIM homeobox 1
chr3_-_149470229 0.08 ENST00000473414.1
 COMMD2
 COMM domain containing 2
chr12_-_10959892 0.08 ENST00000240615.2
 TAS2R8
 taste receptor, type 2, member 8
chr2_-_70780572 0.07 ENST00000450929.1
 TGFA
 transforming growth factor, alpha
chr10_+_86004802 0.05 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
 RGR
 retinal G protein coupled receptor
chr11_-_36619771 0.04 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2
 recombination activating gene 2
chr22_-_43411106 0.04 ENST00000453643.1
ENST00000263246.3
ENST00000337959.4
 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
chr12_-_56727487 0.03 ENST00000548043.1
ENST00000425394.2
 PAN2
 PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_165414414 0.03 ENST00000359842.5
 RXRG
 retinoid X receptor, gamma
chr3_+_138340067 0.03 ENST00000479848.1
 FAIM
 Fas apoptotic inhibitory molecule
chr12_-_56727676 0.02 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
 PAN2
 PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr20_-_43729750 0.02 ENST00000537075.1
ENST00000306117.1
 KCNS1
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr12_-_103310987 0.00 ENST00000307000.2
 PAH
 phenylalanine hydroxylase
chr17_-_12921270 0.00 ENST00000578071.1
ENST00000426905.3
ENST00000395962.2
ENST00000583371.1
ENST00000338034.4
 ELAC2
 elaC ribonuclease Z 2
chr1_-_16563641 0.00 ENST00000375599.3
 RSG1
 REM2 and RAB-like small GTPase 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.2 1.2 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.3 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0097056 seryl-tRNA aminoacylation(GO:0006434) selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.7 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0002329 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 2.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)