Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for E2F2_E2F5

Z-value: 2.27

Motif logo

logo of logo of

Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
E2F2
ENSG00000007968.6 E2F2
E2F5
ENSG00000133740.6 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F5hg19_v2_chr8_+_86121448_861214940.712.0e-03Click!
E2F2hg19_v2_chr1_-_23857698_23857733-0.126.6e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_19263145 5.16 ENST00000532666.1
ENST00000527884.1
 E2F8
 E2F transcription factor 8
chr7_-_99699538 5.06 ENST00000343023.6
ENST00000303887.5
 MCM7
 minichromosome maintenance complex component 7
chr6_-_27114577 4.90 ENST00000356950.1
ENST00000396891.4
 HIST1H2BK
 histone cluster 1, H2bk
chr10_+_62538089 4.83 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
 CDK1
 cyclin-dependent kinase 1
chr10_+_62538248 4.72 ENST00000448257.2
 CDK1
 cyclin-dependent kinase 1
chr6_+_24775641 4.62 ENST00000378054.2
ENST00000476555.1
 GMNN
 geminin, DNA replication inhibitor
chr6_+_135502408 4.47 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
 MYB
 v-myb avian myeloblastosis viral oncogene homolog
chr6_+_135502466 4.35 ENST00000367814.4
 MYB
 v-myb avian myeloblastosis viral oncogene homolog
chr2_-_136633940 4.19 ENST00000264156.2
 MCM6
 minichromosome maintenance complex component 6
chr5_-_79950371 4.18 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
 DHFR
 dihydrofolate reductase
chr11_+_125495862 3.96 ENST00000428830.2
ENST00000544373.1
ENST00000527013.1
ENST00000526937.1
ENST00000534685.1
 CHEK1
 checkpoint kinase 1
chr8_-_124408652 3.83 ENST00000287394.5
 ATAD2
 ATPase family, AAA domain containing 2
chr7_-_148581251 3.75 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr10_+_13203543 3.53 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
 MCM10
 minichromosome maintenance complex component 10
chr14_-_50154921 3.50 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
 POLE2
 polymerase (DNA directed), epsilon 2, accessory subunit
chr3_+_127317066 3.43 ENST00000265056.7
 MCM2
 minichromosome maintenance complex component 2
chr22_+_35796056 3.34 ENST00000216122.4
 MCM5
 minichromosome maintenance complex component 5
chr7_-_148581360 3.29 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
 EZH2
 enhancer of zeste homolog 2 (Drosophila)
chr22_+_35796108 3.21 ENST00000382011.5
ENST00000416905.1
 MCM5
 minichromosome maintenance complex component 5
chr8_-_120868078 3.15 ENST00000313655.4
 DSCC1
 DNA replication and sister chromatid cohesion 1
chr1_-_28241024 3.14 ENST00000313433.7
ENST00000444045.1
 RPA2
 replication protein A2, 32kDa
chr16_-_89007491 3.09 ENST00000327483.5
ENST00000564416.1
 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr20_+_25388293 3.08 ENST00000262460.4
ENST00000429262.2
 GINS1
 GINS complex subunit 1 (Psf1 homolog)
chr5_-_79950775 3.08 ENST00000439211.2
 DHFR
 dihydrofolate reductase
chr6_+_24775153 3.00 ENST00000356509.3
ENST00000230056.3
 GMNN
 geminin, DNA replication inhibitor
chr15_-_64673630 2.87 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
 KIAA0101
 KIAA0101
chr7_+_120591170 2.86 ENST00000431467.1
 ING3
 inhibitor of growth family, member 3
chr16_-_3030283 2.86 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
 PKMYT1
 protein kinase, membrane associated tyrosine/threonine 1
chr2_+_232573208 2.81 ENST00000409115.3
 PTMA
 prothymosin, alpha
chr7_+_120590803 2.79 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
 ING3
 inhibitor of growth family, member 3
chr16_-_3030407 2.79 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
 PKMYT1
 protein kinase, membrane associated tyrosine/threonine 1
chr15_-_66649010 2.78 ENST00000367709.4
ENST00000261881.4
 TIPIN
 TIMELESS interacting protein
chrX_+_24711997 2.77 ENST00000379068.3
ENST00000379059.3
 POLA1
 polymerase (DNA directed), alpha 1, catalytic subunit
chr7_+_139044621 2.59 ENST00000354926.4
 C7orf55-LUC7L2
 C7orf55-LUC7L2 readthrough
chrX_-_152736013 2.57 ENST00000330912.2
ENST00000338525.2
ENST00000334497.2
ENST00000370232.1
ENST00000370212.3
ENST00000370211.4
 TREX2
HAUS7
 three prime repair exonuclease 2
HAUS augmin-like complex, subunit 7
chr15_+_32907691 2.55 ENST00000361627.3
ENST00000567348.1
ENST00000563864.1
ENST00000543522.1
 ARHGAP11A
 Rho GTPase activating protein 11A
chr2_+_232573222 2.46 ENST00000341369.7
ENST00000409683.1
 PTMA
 prothymosin, alpha
chr15_-_64673665 2.45 ENST00000300035.4
 KIAA0101
 KIAA0101
chr1_+_212208919 2.42 ENST00000366991.4
ENST00000542077.1
 DTL
 denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr1_-_26232951 2.39 ENST00000426559.2
ENST00000455785.2
 STMN1
 stathmin 1
chr2_+_10262857 2.39 ENST00000304567.5
 RRM2
 ribonucleotide reductase M2
chr11_-_33891362 2.35 ENST00000395833.3
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr6_+_27806319 2.34 ENST00000606613.1
ENST00000396980.3
 HIST1H2BN
 histone cluster 1, H2bn
chr6_-_52149475 2.23 ENST00000419835.2
ENST00000229854.7
ENST00000596288.1
 MCM3
 minichromosome maintenance complex component 3
chr1_+_228645796 2.09 ENST00000369160.2
 HIST3H2BB
 histone cluster 3, H2bb
chr7_-_158497431 2.04 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
 NCAPG2
 non-SMC condensin II complex, subunit G2
chr6_+_135502501 2.02 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
 MYB
 v-myb avian myeloblastosis viral oncogene homolog
chr2_+_48010312 2.02 ENST00000540021.1
 MSH6
 mutS homolog 6
chr1_-_47779762 2.00 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
 STIL
 SCL/TAL1 interrupting locus
chr20_-_35724388 1.90 ENST00000344359.3
ENST00000373664.3
 RBL1
 retinoblastoma-like 1 (p107)
chr1_-_26232522 1.89 ENST00000399728.1
 STMN1
 stathmin 1
chr8_+_48873479 1.84 ENST00000262105.2
 MCM4
 minichromosome maintenance complex component 4
chr8_+_48873453 1.83 ENST00000523944.1
 MCM4
 minichromosome maintenance complex component 4
chr1_+_25598989 1.81 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chr15_+_40987327 1.81 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
 RAD51
 RAD51 recombinase
chr3_-_48229846 1.79 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
 CDC25A
 cell division cycle 25A
chr2_+_48010221 1.77 ENST00000234420.5
 MSH6
 mutS homolog 6
chr16_-_85722530 1.64 ENST00000253462.3
 GINS2
 GINS complex subunit 2 (Psf2 homolog)
chr19_+_50887585 1.61 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
 POLD1
 polymerase (DNA directed), delta 1, catalytic subunit
chr17_+_30264014 1.60 ENST00000322652.5
ENST00000580398.1
 SUZ12
 SUZ12 polycomb repressive complex 2 subunit
chrX_+_123095546 1.57 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
 STAG2
 stromal antigen 2
chr3_+_44803209 1.53 ENST00000326047.4
 KIF15
 kinesin family member 15
chr12_-_133263893 1.53 ENST00000535270.1
ENST00000320574.5
 POLE
 polymerase (DNA directed), epsilon, catalytic subunit
chr5_+_43121698 1.51 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
 ZNF131
 zinc finger protein 131
chr7_+_116593568 1.43 ENST00000446490.1
 ST7
 suppression of tumorigenicity 7
chr1_-_32801825 1.42 ENST00000329421.7
 MARCKSL1
 MARCKS-like 1
chr1_-_28241226 1.42 ENST00000373912.3
ENST00000373909.3
 RPA2
 replication protein A2, 32kDa
chr12_+_133264156 1.38 ENST00000317479.3
ENST00000543589.1
 PXMP2
 peroxisomal membrane protein 2, 22kDa
chr6_-_35656712 1.38 ENST00000357266.4
ENST00000542713.1
 FKBP5
 FK506 binding protein 5
chr22_+_20105012 1.36 ENST00000331821.3
ENST00000411892.1
 RANBP1
 RAN binding protein 1
chr1_-_25747283 1.35 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
 RHCE
 Rh blood group, CcEe antigens
chr8_+_128748308 1.34 ENST00000377970.2
 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
chrX_+_131157290 1.33 ENST00000394334.2
 MST4
 Serine/threonine-protein kinase MST4
chr1_+_25598872 1.32 ENST00000328664.4
 RHD
 Rh blood group, D antigen
chr6_-_27775694 1.29 ENST00000377401.2
 HIST1H2BL
 histone cluster 1, H2bl
chr6_+_37137939 1.29 ENST00000373509.5
 PIM1
 pim-1 oncogene
chrX_+_131157322 1.29 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
 MST4
 Serine/threonine-protein kinase MST4
chr1_+_233749739 1.28 ENST00000366621.3
 KCNK1
 potassium channel, subfamily K, member 1
chr11_-_19262486 1.25 ENST00000250024.4
 E2F8
 E2F transcription factor 8
chr7_+_116593433 1.25 ENST00000323984.3
ENST00000393449.1
 ST7
 suppression of tumorigenicity 7
chr6_+_27775899 1.24 ENST00000358739.3
 HIST1H2AI
 histone cluster 1, H2ai
chr5_+_43120985 1.23 ENST00000515326.1
 ZNF131
 zinc finger protein 131
chr5_+_36152179 1.22 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_-_58120996 1.21 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
 ZWINT
 ZW10 interacting kinetochore protein
chr3_-_53080047 1.21 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
 SFMBT1
 Scm-like with four mbt domains 1
chr6_+_27100811 1.20 ENST00000359193.2
 HIST1H2AG
 histone cluster 1, H2ag
chr7_+_50344289 1.19 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
chr1_-_212208842 1.19 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
 INTS7
 integrator complex subunit 7
chr6_-_27100529 1.17 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
 HIST1H2BJ
 histone cluster 1, H2bj
chr9_+_126773880 1.15 ENST00000373615.4
 LHX2
 LIM homeobox 2
chr22_-_29137771 1.13 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
 CHEK2
 checkpoint kinase 2
chr5_+_43121607 1.12 ENST00000509156.1
ENST00000508259.1
ENST00000306938.4
ENST00000399534.1
 ZNF131
 zinc finger protein 131
chr9_+_106856831 1.11 ENST00000303219.8
ENST00000374787.3
 SMC2
 structural maintenance of chromosomes 2
chr10_+_112327425 1.11 ENST00000361804.4
 SMC3
 structural maintenance of chromosomes 3
chr12_+_109535923 1.10 ENST00000336865.2
 UNG
 uracil-DNA glycosylase
chr9_-_35080013 1.10 ENST00000378643.3
 FANCG
 Fanconi anemia, complementation group G
chr11_+_4116054 1.09 ENST00000423050.2
 RRM1
 ribonucleotide reductase M1
chr5_+_36152091 1.08 ENST00000274254.5
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr3_-_141868293 1.07 ENST00000317104.7
ENST00000494358.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_25599018 1.05 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
 RHD
 Rh blood group, D antigen
chr13_+_114238997 1.05 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr4_+_71859156 1.04 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
 DCK
 deoxycytidine kinase
chr16_+_58426296 1.03 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
 GINS3
 GINS complex subunit 3 (Psf3 homolog)
chr4_-_174256276 1.01 ENST00000296503.5
 HMGB2
 high mobility group box 2
chr8_+_128748466 1.01 ENST00000524013.1
ENST00000520751.1
 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
chr16_+_29817399 1.01 ENST00000545521.1
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_36706024 1.00 ENST00000443387.2
 ZNF146
 zinc finger protein 146
chr22_-_20104700 0.98 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
 TRMT2A
 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr17_+_29158962 0.97 ENST00000321990.4
 ATAD5
 ATPase family, AAA domain containing 5
chr17_-_17184605 0.96 ENST00000268717.5
 COPS3
 COP9 signalosome subunit 3
chr3_-_141868357 0.96 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr2_+_47630108 0.95 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
 MSH2
 mutS homolog 2
chr5_+_79950463 0.94 ENST00000265081.6
 MSH3
 mutS homolog 3
chr3_+_14219858 0.92 ENST00000306024.3
 LSM3
 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr1_+_66458072 0.92 ENST00000423207.2
 PDE4B
 phosphodiesterase 4B, cAMP-specific
chr5_+_36876833 0.92 ENST00000282516.8
ENST00000448238.2
 NIPBL
 Nipped-B homolog (Drosophila)
chr7_-_44887620 0.91 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
 H2AFV
 H2A histone family, member V
chr17_+_58677539 0.91 ENST00000305921.3
 PPM1D
 protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr11_+_64808368 0.88 ENST00000531072.1
ENST00000398846.1
 SAC3D1
 SAC3 domain containing 1
chr14_-_69864993 0.88 ENST00000555373.1
 ERH
 enhancer of rudimentary homolog (Drosophila)
chr19_+_10765699 0.87 ENST00000590009.1
 ILF3
 interleukin enhancer binding factor 3, 90kDa
chr15_-_70388943 0.87 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr6_-_144329531 0.86 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
 PLAGL1
 pleiomorphic adenoma gene-like 1
chr13_+_32889605 0.85 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
 BRCA2
 breast cancer 2, early onset
chrX_+_48554986 0.82 ENST00000376687.3
ENST00000453214.2
 SUV39H1
 suppressor of variegation 3-9 homolog 1 (Drosophila)
chr20_-_32274179 0.82 ENST00000343380.5
 E2F1
 E2F transcription factor 1
chr6_-_27782548 0.81 ENST00000333151.3
 HIST1H2AJ
 histone cluster 1, H2aj
chr9_+_106856541 0.78 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
 SMC2
 structural maintenance of chromosomes 2
chr6_+_35995552 0.75 ENST00000468133.1
 MAPK14
 mitogen-activated protein kinase 14
chrX_-_135849484 0.75 ENST00000370620.1
ENST00000535227.1
 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_-_54303934 0.73 ENST00000537333.1
 NDC1
 NDC1 transmembrane nucleoporin
chr1_+_100598691 0.72 ENST00000370143.1
ENST00000370141.2
 TRMT13
 tRNA methyltransferase 13 homolog (S. cerevisiae)
chr11_+_74303575 0.71 ENST00000263681.2
 POLD3
 polymerase (DNA-directed), delta 3, accessory subunit
chr13_-_79177673 0.71 ENST00000377208.5
 POU4F1
 POU class 4 homeobox 1
chr11_+_64808675 0.71 ENST00000529996.1
 SAC3D1
 SAC3 domain containing 1
chr14_+_51706886 0.70 ENST00000457354.2
 TMX1
 thioredoxin-related transmembrane protein 1
chr19_-_10305752 0.69 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
 DNMT1
 DNA (cytosine-5-)-methyltransferase 1
chr18_+_19192228 0.68 ENST00000300413.5
ENST00000579618.1
ENST00000582475.1
 SNRPD1
 small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr16_-_23607598 0.66 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
 NDUFAB1
 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr7_+_26241325 0.66 ENST00000456948.1
ENST00000409747.1
 CBX3
 chromobox homolog 3
chr9_+_86595626 0.65 ENST00000445877.1
ENST00000325875.3
 RMI1
 RecQ mediated genome instability 1
chr10_-_21786179 0.64 ENST00000377113.5
 CASC10
 cancer susceptibility candidate 10
chr3_-_133380731 0.64 ENST00000260810.5
 TOPBP1
 topoisomerase (DNA) II binding protein 1
chr4_+_129730779 0.64 ENST00000226319.6
 PHF17
 jade family PHD finger 1
chr10_-_13390021 0.62 ENST00000537130.1
 SEPHS1
 selenophosphate synthetase 1
chr4_+_178230985 0.62 ENST00000264596.3
 NEIL3
 nei endonuclease VIII-like 3 (E. coli)
chr17_-_74733404 0.61 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
 SRSF2
 serine/arginine-rich splicing factor 2
chr6_+_30312908 0.59 ENST00000433076.2
ENST00000442966.2
ENST00000428040.2
ENST00000436442.2
 RPP21
 ribonuclease P/MRP 21kDa subunit
chr20_-_5100591 0.59 ENST00000379143.5
 PCNA
 proliferating cell nuclear antigen
chr6_+_84569359 0.59 ENST00000369681.5
ENST00000369679.4
 CYB5R4
 cytochrome b5 reductase 4
chr3_-_169381183 0.58 ENST00000494292.1
 MECOM
 MDS1 and EVI1 complex locus
chr1_+_33116743 0.58 ENST00000414241.3
ENST00000373493.5
 RBBP4
 retinoblastoma binding protein 4
chr19_+_1383890 0.58 ENST00000539480.1
ENST00000313408.7
ENST00000414651.2
 NDUFS7
 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
chr12_-_31479045 0.57 ENST00000539409.1
ENST00000395766.1
 FAM60A
 family with sequence similarity 60, member A
chr6_+_35995488 0.56 ENST00000229795.3
 MAPK14
 mitogen-activated protein kinase 14
chr6_-_17706618 0.54 ENST00000262077.2
ENST00000537253.1
 NUP153
 nucleoporin 153kDa
chr19_+_36705504 0.54 ENST00000456324.1
 ZNF146
 zinc finger protein 146
chr6_+_35995531 0.53 ENST00000229794.4
 MAPK14
 mitogen-activated protein kinase 14
chr7_-_105516923 0.51 ENST00000478915.1
 ATXN7L1
 ataxin 7-like 1
chr3_-_185655795 0.50 ENST00000342294.4
ENST00000382191.4
ENST00000453386.2
 TRA2B
 transformer 2 beta homolog (Drosophila)
chr1_-_222885770 0.50 ENST00000355727.2
ENST00000340020.6
 AIDA
 axin interactor, dorsalization associated
chr4_+_129730947 0.50 ENST00000452328.2
ENST00000504089.1
 PHF17
 jade family PHD finger 1
chrX_+_106871713 0.50 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
 PRPS1
 phosphoribosyl pyrophosphate synthetase 1
chr19_+_50432400 0.49 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
 ATF5
 activating transcription factor 5
chr19_+_49588677 0.49 ENST00000598984.1
ENST00000598441.1
 SNRNP70
 small nuclear ribonucleoprotein 70kDa (U1)
chr22_-_38966172 0.49 ENST00000216024.2
 DMC1
 DNA meiotic recombinase 1
chr5_+_133861790 0.48 ENST00000395003.1
 PHF15
 jade family PHD finger 2
chr7_+_26241310 0.48 ENST00000396386.2
 CBX3
 chromobox homolog 3
chr3_-_51975942 0.47 ENST00000232888.6
 RRP9
 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr3_+_16926441 0.47 ENST00000418129.2
ENST00000396755.2
 PLCL2
 phospholipase C-like 2
chr6_+_27114861 0.47 ENST00000377459.1
 HIST1H2AH
 histone cluster 1, H2ah
chr4_-_39979576 0.47 ENST00000303538.8
ENST00000503396.1
 PDS5A
 PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr6_+_88299833 0.46 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
 ORC3
 origin recognition complex, subunit 3
chr2_+_61108771 0.45 ENST00000394479.3
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr7_-_105517021 0.43 ENST00000318724.4
ENST00000419735.3
 ATXN7L1
 ataxin 7-like 1
chr3_+_134514093 0.43 ENST00000398015.3
 EPHB1
 EPH receptor B1
chr1_-_26233423 0.42 ENST00000357865.2
 STMN1
 stathmin 1
chr12_-_49245936 0.42 ENST00000308025.3
 DDX23
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr12_-_51611477 0.41 ENST00000389243.4
 POU6F1
 POU class 6 homeobox 1
chr5_-_140998616 0.41 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
 DIAPH1
 diaphanous-related formin 1
chr16_+_3019552 0.39 ENST00000572687.1
 PAQR4
 progestin and adipoQ receptor family member IV
chr19_-_50432654 0.39 ENST00000596680.1
ENST00000594673.1
ENST00000597029.1
 NUP62
 nucleoporin 62kDa
chr1_-_149982624 0.38 ENST00000417191.1
ENST00000369135.4
 OTUD7B
 OTU domain containing 7B
chr7_-_150924121 0.38 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
 ABCF2
 ATP-binding cassette, sub-family F (GCN20), member 2
chr16_-_30102547 0.37 ENST00000279386.2
 TBX6
 T-box 6
chr15_+_66994561 0.37 ENST00000288840.5
 SMAD6
 SMAD family member 6
chr3_+_182511266 0.37 ENST00000323116.5
ENST00000493826.1
 ATP11B
 ATPase, class VI, type 11B
chr5_+_36152163 0.37 ENST00000274255.6
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr11_+_66384053 0.36 ENST00000310137.4
ENST00000393979.3
ENST00000409372.1
ENST00000443702.1
ENST00000409738.4
ENST00000514361.3
ENST00000503028.2
ENST00000412278.2
ENST00000500635.2
 RBM14
RBM4
RBM14-RBM4
 RNA binding motif protein 14
RNA binding motif protein 4
RBM14-RBM4 readthrough
chr10_-_13390270 0.36 ENST00000378614.4
ENST00000545675.1
ENST00000327347.5
 SEPHS1
 selenophosphate synthetase 1
chr6_+_31633011 0.36 ENST00000375885.4
 CSNK2B
 casein kinase 2, beta polypeptide
chr16_+_67596310 0.36 ENST00000264010.4
ENST00000401394.1
 CTCF
 CCCTC-binding factor (zinc finger protein)
chr5_+_75378997 0.35 ENST00000502798.2
 SV2C
 synaptic vesicle glycoprotein 2C
chr9_-_120177216 0.35 ENST00000373996.3
ENST00000313400.4
ENST00000361477.3
 ASTN2
 astrotactin 2
chr1_-_151119087 0.35 ENST00000341697.3
ENST00000368914.3
 SEMA6C
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr1_-_23670752 0.35 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
 HNRNPR
 heterogeneous nuclear ribonucleoprotein R
chr6_-_5260963 0.34 ENST00000464010.1
ENST00000468929.1
ENST00000480566.1
 LYRM4
 LYR motif containing 4
chr22_+_31031639 0.34 ENST00000343605.4
ENST00000300385.8
 SLC35E4
 solute carrier family 35, member E4
chr19_-_50432711 0.34 ENST00000597723.1
ENST00000599788.1
ENST00000596217.1
ENST00000593652.1
ENST00000599567.1
ENST00000600935.1
ENST00000596011.1
ENST00000596022.1
ENST00000597295.1
 NUP62
IL4I1
 nucleoporin 62kDa
interleukin 4 induced 1
chr5_+_140019079 0.33 ENST00000252100.6
 TMCO6
 transmembrane and coiled-coil domains 6

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.3 GO:0051870 methotrexate binding(GO:0051870)
1.2 4.7 GO:0032143 single thymine insertion binding(GO:0032143)
1.0 8.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.9 0.9 GO:0000404 heteroduplex DNA loop binding(GO:0000404) double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.9 3.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.8 14.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.8 9.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.7 4.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.6 5.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.5 1.9 GO:0036033 mediator complex binding(GO:0036033)
0.5 5.7 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.4 4.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.4 4.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.4 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 12.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 9.5 GO:0035173 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) histone kinase activity(GO:0035173)
0.3 1.0 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.3 1.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3 0.6 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.3 7.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 1.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 0.7 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.2 5.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.8 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.4 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 7.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 8.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.9 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0070697 activin receptor binding(GO:0070697)
0.1 7.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0000150 recombinase activity(GO:0000150)
0.1 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 1.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 7.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 5.3 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 12.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 2.2 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 5.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.8 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 5.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 29.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.0 26.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.8 11.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4 6.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.4 7.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.3 5.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 12.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 1.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 2.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 12.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 5.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.9 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 2.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 25.1 GO:0042555 MCM complex(GO:0042555)
1.9 9.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.4 5.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.2 4.7 GO:0032301 MutSalpha complex(GO:0032301)
1.2 4.7 GO:0000811 GINS complex(GO:0000811)
1.1 6.3 GO:0031298 replication fork protection complex(GO:0031298)
1.0 5.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.9 0.9 GO:0032302 MutSbeta complex(GO:0032302)
0.9 3.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.6 2.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 2.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 3.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 1.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.5 7.0 GO:0045120 pronucleus(GO:0045120)
0.5 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 3.9 GO:0000796 condensin complex(GO:0000796)
0.4 1.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 4.6 GO:0043601 nuclear replisome(GO:0043601)
0.3 0.6 GO:0030894 replisome(GO:0030894)
0.3 2.6 GO:0070652 HAUS complex(GO:0070652)
0.3 0.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 1.6 GO:0001739 sex chromatin(GO:0001739)
0.3 2.7 GO:0000800 lateral element(GO:0000800)
0.3 1.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 0.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 13.8 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.2 2.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 2.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 0.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.3 GO:0000243 commitment complex(GO:0000243)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 11.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 4.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.3 GO:0033503 HULC complex(GO:0033503)
0.1 0.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.9 GO:0034709 methylosome(GO:0034709)
0.1 1.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 2.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 10.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 2.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.0 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.8 GO:0005819 spindle(GO:0005819)
0.0 0.9 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 17.9 PID ATR PATHWAY ATR signaling pathway
0.3 4.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 23.8 PID E2F PATHWAY E2F transcription factor network
0.2 10.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 6.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.0 PID ATM PATHWAY ATM pathway
0.1 3.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
2.3 7.0 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
1.8 18.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.8 7.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
1.6 9.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
1.3 6.4 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.3 7.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
1.2 4.9 GO:0006272 leading strand elongation(GO:0006272)
0.9 4.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.7 3.6 GO:0048478 replication fork protection(GO:0048478)
0.7 4.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.6 5.7 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.6 3.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 5.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 2.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.5 18.6 GO:0006270 DNA replication initiation(GO:0006270)
0.4 6.9 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.4 3.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.4 2.3 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.4 3.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.4 1.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.8 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 2.0 GO:0033504 floor plate development(GO:0033504)
0.3 1.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.3 6.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 0.9 GO:0061010 gall bladder development(GO:0061010)
0.3 1.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.2 0.7 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 0.7 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 1.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 2.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.9 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 1.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 5.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 1.7 GO:0021978 telencephalon regionalization(GO:0021978)
0.2 1.0 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.2 5.5 GO:0015695 organic cation transport(GO:0015695)
0.2 1.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 0.5 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.2 3.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:0099545 trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 1.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.5 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.6 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 2.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.4 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 1.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 1.6 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.0 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0035822 gene conversion(GO:0035822)
0.1 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 7.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.6 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0042148 strand invasion(GO:0042148)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.3 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 3.2 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.4 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.4 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.5 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 1.4 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.7 GO:0000732 strand displacement(GO:0000732)
0.0 0.9 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0033197 response to vitamin E(GO:0033197)
0.0 1.7 GO:0001510 RNA methylation(GO:0001510)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.9 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 1.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.5 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 1.1 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 2.0 GO:0051225 spindle assembly(GO:0051225)
0.0 1.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 1.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.1 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)