ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
E2F4 Links Ensembl NCBI GeneCards UniProt	ENSG00000205250.4	E2F4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F4	hg19_v2_chr16_+_67226019_67226127	0.29	2.7e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_+_135502408	1.27	ENST00000341911.5 ENST00000442647.2 ENST00000316528.8	MYB	v-myb avian myeloblastosis viral oncogene homolog
chr6_+_135502466	1.25	ENST00000367814.4	MYB	v-myb avian myeloblastosis viral oncogene homolog
chr15_+_91260552	1.11	ENST00000355112.3 ENST00000560509.1	BLM	Bloom syndrome, RecQ helicase-like
chrX_+_109245863	1.06	ENST00000372072.3	TMEM164	transmembrane protein 164
chr8_+_48873453	1.04	ENST00000523944.1	MCM4	minichromosome maintenance complex component 4
chr8_+_48873479	1.04	ENST00000262105.2	MCM4	minichromosome maintenance complex component 4
chr1_+_91966384	1.01	ENST00000430031.2 ENST00000234626.6	CDC7	cell division cycle 7
chr22_+_19467261	0.97	ENST00000455750.1 ENST00000437685.2 ENST00000263201.1 ENST00000404724.3	CDC45	cell division cycle 45
chr15_+_51973680	0.97	ENST00000542355.2	SCG3	secretogranin III
chr15_+_51973550	0.96	ENST00000220478.3	SCG3	secretogranin III
chr1_+_91966656	0.95	ENST00000428239.1 ENST00000426137.1	CDC7	cell division cycle 7
chr7_-_99698338	0.93	ENST00000354230.3 ENST00000425308.1	MCM7	minichromosome maintenance complex component 7
chr4_-_73434498	0.93	ENST00000286657.4	ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_26185844	0.91	ENST00000538789.1 ENST00000374298.3	AUNIP	aurora kinase A and ninein interacting protein
chr19_+_18284477	0.88	ENST00000407280.3	IFI30	interferon, gamma-inducible protein 30
chr2_+_172778952	0.87	ENST00000392584.1 ENST00000264108.4	HAT1	histone acetyltransferase 1
chr6_-_27114577	0.87	ENST00000356950.1 ENST00000396891.4	HIST1H2BK	histone cluster 1, H2bk
chr4_-_185655278	0.83	ENST00000281453.5	MLF1IP	centromere protein U
chr8_-_41754231	0.82	ENST00000265709.8	ANK1	ankyrin 1, erythrocytic
chr10_-_70231639	0.76	ENST00000551118.2 ENST00000358410.3 ENST00000399180.2 ENST00000399179.2	DNA2	DNA replication helicase/nuclease 2
chrX_+_109246285	0.76	ENST00000372073.1 ENST00000372068.2 ENST00000288381.4	TMEM164	transmembrane protein 164
chr14_-_55658323	0.76	ENST00000554067.1 ENST00000247191.2	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr21_-_33651324	0.75	ENST00000290130.3	MIS18A	MIS18 kinetochore protein A
chr1_-_229761717	0.74	ENST00000366675.3 ENST00000258281.2 ENST00000366674.1	TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr5_-_79950371	0.73	ENST00000511032.1 ENST00000504396.1 ENST00000505337.1	DHFR	dihydrofolate reductase
chr18_+_33767473	0.72	ENST00000261326.5	MOCOS	molybdenum cofactor sulfurase
chr1_-_145076186	0.72	ENST00000369348.3	PDE4DIP	phosphodiesterase 4D interacting protein
chr9_-_124991124	0.69	ENST00000394319.4 ENST00000340587.3	LHX6	LIM homeobox 6
chr1_-_28241024	0.69	ENST00000313433.7 ENST00000444045.1	RPA2	replication protein A2, 32kDa
chr19_-_49944806	0.69	ENST00000221485.3	SLC17A7	solute carrier family 17 (vesicular glutamate transporter), member 7
chr7_+_138145145	0.67	ENST00000415680.2	TRIM24	tripartite motif containing 24
chr19_+_50887585	0.66	ENST00000440232.2 ENST00000601098.1 ENST00000599857.1 ENST00000593887.1	POLD1	polymerase (DNA directed), delta 1, catalytic subunit
chr7_-_73668692	0.66	ENST00000352131.3 ENST00000055077.3	RFC2	replication factor C (activator 1) 2, 40kDa
chr2_+_48010312	0.64	ENST00000540021.1	MSH6	mutS homolog 6
chr8_-_95907423	0.64	ENST00000396133.3 ENST00000308108.4	CCNE2	cyclin E2
chr2_+_47630255	0.63	ENST00000406134.1	MSH2	mutS homolog 2
chr14_-_50154921	0.63	ENST00000553805.2 ENST00000554396.1 ENST00000216367.5 ENST00000539565.2	POLE2	polymerase (DNA directed), epsilon 2, accessory subunit
chr7_+_138145076	0.61	ENST00000343526.4	TRIM24	tripartite motif containing 24
chr2_+_47630108	0.60	ENST00000233146.2 ENST00000454849.1 ENST00000543555.1	MSH2	mutS homolog 2
chr15_+_48624300	0.59	ENST00000455976.2 ENST00000559540.1	DUT	deoxyuridine triphosphatase
chr21_-_44496441	0.59	ENST00000359624.3 ENST00000352178.5	CBS	cystathionine-beta-synthase
chr3_-_33759699	0.57	ENST00000399362.4 ENST00000359576.5 ENST00000307312.7	CLASP2	cytoplasmic linker associated protein 2
chr6_+_27100811	0.57	ENST00000359193.2	HIST1H2AG	histone cluster 1, H2ag
chr2_+_48010221	0.56	ENST00000234420.5	MSH6	mutS homolog 6
chr6_+_135502501	0.56	ENST00000527615.1 ENST00000420123.2 ENST00000525369.1 ENST00000528774.1 ENST00000534121.1 ENST00000534044.1 ENST00000533624.1	MYB	v-myb avian myeloblastosis viral oncogene homolog
chr13_+_34392185	0.56	ENST00000380071.3	RFC3	replication factor C (activator 1) 3, 38kDa
chr1_+_173793641	0.56	ENST00000361951.4	DARS2	aspartyl-tRNA synthetase 2, mitochondrial
chr16_+_2510081	0.55	ENST00000361837.4 ENST00000569496.1 ENST00000567489.1 ENST00000563531.1 ENST00000483320.1	C16orf59	chromosome 16 open reading frame 59
chr1_+_63833261	0.55	ENST00000371108.4	ALG6	ALG6, alpha-1,3-glucosyltransferase
chr1_+_10490779	0.55	ENST00000477755.1	APITD1	apoptosis-inducing, TAF9-like domain 1
chr5_+_892745	0.54	ENST00000166345.3	TRIP13	thyroid hormone receptor interactor 13
chr11_-_118972575	0.54	ENST00000432443.2	DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr12_-_56843161	0.54	ENST00000554616.1 ENST00000553532.1 ENST00000229201.4	TIMELESS	timeless circadian clock
chr21_-_34915147	0.52	ENST00000381831.3 ENST00000381839.3	GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr1_+_28844648	0.52	ENST00000373832.1 ENST00000373831.3	RCC1	regulator of chromosome condensation 1
chr6_-_27100529	0.51	ENST00000607124.1 ENST00000339812.2 ENST00000541790.1	HIST1H2BJ	histone cluster 1, H2bj
chr15_-_50647274	0.50	ENST00000543881.1	GABPB1	GA binding protein transcription factor, beta subunit 1
chr3_-_33759541	0.50	ENST00000468888.2	CLASP2	cytoplasmic linker associated protein 2
chr1_+_28844778	0.49	ENST00000411533.1	RCC1	regulator of chromosome condensation 1
chr12_-_57146095	0.48	ENST00000550770.1 ENST00000338193.6	PRIM1	primase, DNA, polypeptide 1 (49kDa)
chr12_+_102514019	0.48	ENST00000537257.1 ENST00000358383.5 ENST00000392911.2	PARPBP	PARP1 binding protein
chr20_+_42295745	0.47	ENST00000396863.4 ENST00000217026.4	MYBL2	v-myb avian myeloblastosis viral oncogene homolog-like 2
chr4_-_1714037	0.47	ENST00000488267.1 ENST00000429429.2 ENST00000480936.1	SLBP	stem-loop binding protein
chr12_+_102513950	0.47	ENST00000378128.3 ENST00000327680.2 ENST00000541394.1 ENST00000543784.1	PARPBP	PARP1 binding protein
chr8_-_103136481	0.47	ENST00000524209.1 ENST00000517822.1 ENST00000523923.1 ENST00000521599.1 ENST00000521964.1 ENST00000311028.3 ENST00000518166.1	NCALD	neurocalcin delta
chr1_+_173793777	0.44	ENST00000239457.5	DARS2	aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_197115818	0.44	ENST00000367409.4 ENST00000294732.7	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr10_+_92631709	0.44	ENST00000413330.1 ENST00000277882.3	RPP30	ribonuclease P/MRP 30kDa subunit
chr10_-_43892279	0.44	ENST00000443950.2	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr2_+_68384976	0.43	ENST00000263657.2	PNO1	partner of NOB1 homolog (S. cerevisiae)
chr6_-_52149475	0.42	ENST00000419835.2 ENST00000229854.7 ENST00000596288.1	MCM3	minichromosome maintenance complex component 3
chr11_-_73694346	0.41	ENST00000310473.3	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)
chr4_-_1713977	0.41	ENST00000318386.4	SLBP	stem-loop binding protein
chr1_+_10490441	0.40	ENST00000470413.2 ENST00000309048.3	APITD1-CORT APITD1	APITD1-CORT readthrough apoptosis-inducing, TAF9-like domain 1
chr6_+_167412835	0.40	ENST00000349556.4	FGFR1OP	FGFR1 oncogene partner
chr1_+_27248203	0.40	ENST00000321265.5	NUDC	nudC nuclear distribution protein
chr3_-_148804275	0.39	ENST00000392912.2 ENST00000465259.1 ENST00000310053.5 ENST00000494055.1	HLTF	helicase-like transcription factor
chr15_-_50647370	0.39	ENST00000558970.1 ENST00000396464.3 ENST00000560825.1	GABPB1	GA binding protein transcription factor, beta subunit 1
chr17_-_76183111	0.38	ENST00000405273.1 ENST00000590862.1 ENST00000590430.1 ENST00000586613.1	TK1	thymidine kinase 1, soluble
chr16_-_67693846	0.37	ENST00000602850.1	ACD	adrenocortical dysplasia homolog (mouse)
chr7_+_100026406	0.37	ENST00000414441.1	MEPCE	methylphosphate capping enzyme
chr4_+_178230985	0.37	ENST00000264596.3	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr19_-_12912601	0.37	ENST00000334482.5	PRDX2	peroxiredoxin 2
chr8_+_128748308	0.37	ENST00000377970.2	MYC	v-myc avian myelocytomatosis viral oncogene homolog
chr17_-_34890759	0.37	ENST00000431794.3	MYO19	myosin XIX
chr1_-_241683001	0.36	ENST00000366560.3	FH	fumarate hydratase
chr8_+_128748466	0.36	ENST00000524013.1 ENST00000520751.1	MYC	v-myc avian myelocytomatosis viral oncogene homolog
chr10_-_43892668	0.36	ENST00000544000.1	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr19_-_6424783	0.36	ENST00000398148.3	KHSRP	KH-type splicing regulatory protein
chr11_+_32914579	0.35	ENST00000399302.2	QSER1	glutamine and serine rich 1
chr17_+_73106035	0.35	ENST00000581078.1 ENST00000582136.1 ENST00000245543.1	ARMC7	armadillo repeat containing 7
chr12_-_57472522	0.35	ENST00000379391.3 ENST00000300128.4	TMEM194A	transmembrane protein 194A
chr1_-_28241226	0.35	ENST00000373912.3 ENST00000373909.3	RPA2	replication protein A2, 32kDa
chr7_-_102985288	0.35	ENST00000379263.3	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr2_+_10262857	0.34	ENST00000304567.5	RRM2	ribonucleotide reductase M2
chr11_+_58910201	0.34	ENST00000528737.1	FAM111A	family with sequence similarity 111, member A
chr7_-_129845188	0.34	ENST00000462753.1 ENST00000471077.1 ENST00000473456.1 ENST00000336804.8	TMEM209	transmembrane protein 209
chr9_-_124990680	0.33	ENST00000541397.2 ENST00000560485.1	LHX6	LIM homeobox 6
chr11_+_58910295	0.33	ENST00000420244.1	FAM111A	family with sequence similarity 111, member A
chr8_+_124084899	0.33	ENST00000287380.1 ENST00000309336.3 ENST00000519418.1 ENST00000327098.5 ENST00000522420.1 ENST00000521676.1 ENST00000378080.2	TBC1D31	TBC1 domain family, member 31
chr16_+_68119440	0.33	ENST00000346183.3 ENST00000329524.4	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr22_-_42343117	0.32	ENST00000407253.3 ENST00000215980.5	CENPM	centromere protein M
chr15_+_89631647	0.32	ENST00000569550.1 ENST00000565066.1 ENST00000565973.1	ABHD2	abhydrolase domain containing 2
chr1_+_114472222	0.32	ENST00000369558.1 ENST00000369561.4	HIPK1	homeodomain interacting protein kinase 1
chr7_+_130794846	0.32	ENST00000421797.2	MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr16_+_29817399	0.32	ENST00000545521.1	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr22_-_42342692	0.31	ENST00000404067.1 ENST00000402338.1	CENPM	centromere protein M
chr19_-_12912657	0.31	ENST00000301522.2	PRDX2	peroxiredoxin 2
chr3_-_185655795	0.31	ENST00000342294.4 ENST00000382191.4 ENST00000453386.2	TRA2B	transformer 2 beta homolog (Drosophila)
chr6_+_167412665	0.30	ENST00000366847.4	FGFR1OP	FGFR1 oncogene partner
chr22_+_20105012	0.30	ENST00000331821.3 ENST00000411892.1	RANBP1	RAN binding protein 1
chr5_+_141348640	0.29	ENST00000540015.1 ENST00000506938.1 ENST00000394514.2 ENST00000512565.1 ENST00000394515.3	RNF14	ring finger protein 14
chr20_+_47662805	0.29	ENST00000262982.2 ENST00000542325.1	CSE1L	CSE1 chromosome segregation 1-like (yeast)
chr5_+_141348598	0.29	ENST00000394520.2 ENST00000347642.3	RNF14	ring finger protein 14
chr14_+_105219437	0.29	ENST00000329967.6 ENST00000347067.5 ENST00000553810.1	SIVA1	SIVA1, apoptosis-inducing factor
chr7_-_129845313	0.29	ENST00000397622.2	TMEM209	transmembrane protein 209
chr19_-_1095330	0.28	ENST00000586746.1	POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
chr17_+_5390220	0.28	ENST00000381165.3	MIS12	MIS12 kinetochore complex component
chr1_+_11333245	0.28	ENST00000376810.5	UBIAD1	UbiA prenyltransferase domain containing 1
chr6_+_30687978	0.28	ENST00000327892.8 ENST00000435534.1	TUBB	tubulin, beta class I
chr1_+_33116743	0.27	ENST00000414241.3 ENST00000373493.5	RBBP4	retinoblastoma binding protein 4
chr2_-_97535708	0.27	ENST00000305476.5	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr17_+_61678225	0.27	ENST00000258975.6	TACO1	translational activator of mitochondrially encoded cytochrome c oxidase I
chr1_-_33283754	0.27	ENST00000373477.4	YARS	tyrosyl-tRNA synthetase
chr9_-_77567743	0.27	ENST00000376854.5	C9orf40	chromosome 9 open reading frame 40
chr8_-_124408652	0.27	ENST00000287394.5	ATAD2	ATPase family, AAA domain containing 2
chr4_+_128802016	0.27	ENST00000270861.5 ENST00000515069.1 ENST00000513090.1 ENST00000507249.1	PLK4	polo-like kinase 4
chr7_-_44887620	0.26	ENST00000349299.3 ENST00000521529.1 ENST00000308153.4 ENST00000350771.3 ENST00000222690.6 ENST00000381124.5 ENST00000437072.1 ENST00000446531.1	H2AFV	H2A histone family, member V
chr7_+_116593433	0.26	ENST00000323984.3 ENST00000393449.1	ST7	suppression of tumorigenicity 7
chr19_-_48673580	0.26	ENST00000427526.2	LIG1	ligase I, DNA, ATP-dependent
chr17_-_41277467	0.26	ENST00000494123.1 ENST00000346315.3 ENST00000309486.4 ENST00000468300.1 ENST00000354071.3 ENST00000352993.3 ENST00000471181.2	BRCA1	breast cancer 1, early onset
chr14_-_71067360	0.26	ENST00000554963.1 ENST00000430055.2 ENST00000440435.2 ENST00000256379.5	MED6	mediator complex subunit 6
chr12_-_102513843	0.26	ENST00000551744.2 ENST00000552283.1	NUP37	nucleoporin 37kDa
chr15_+_40987327	0.26	ENST00000423169.2 ENST00000267868.3 ENST00000557850.1 ENST00000532743.1 ENST00000382643.3	RAD51	RAD51 recombinase
chr6_-_34855773	0.25	ENST00000420584.2 ENST00000361288.4	TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr6_+_57182400	0.25	ENST00000607273.1	PRIM2	primase, DNA, polypeptide 2 (58kDa)
chr11_+_110300607	0.25	ENST00000260270.2	FDX1	ferredoxin 1
chr1_+_114471972	0.25	ENST00000369559.4 ENST00000369554.2	HIPK1	homeodomain interacting protein kinase 1
chr10_-_62493223	0.25	ENST00000373827.2	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr11_+_34073195	0.25	ENST00000341394.4	CAPRIN1	cell cycle associated protein 1
chr5_+_177631523	0.25	ENST00000506339.1 ENST00000355836.5 ENST00000514633.1 ENST00000515193.1 ENST00000506259.1 ENST00000504898.1	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
chr16_-_4401258	0.25	ENST00000577031.1	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr19_+_50180317	0.25	ENST00000534465.1	PRMT1	protein arginine methyltransferase 1
chr15_-_74988281	0.25	ENST00000566828.1 ENST00000563009.1 ENST00000568176.1 ENST00000566243.1 ENST00000566219.1 ENST00000426797.3 ENST00000566119.1 ENST00000315127.4	EDC3	enhancer of mRNA decapping 3
chr3_+_133502877	0.24	ENST00000466490.2	SRPRB	signal recognition particle receptor, B subunit
chr21_-_34100244	0.24	ENST00000382491.3 ENST00000357345.3 ENST00000429236.1	SYNJ1	synaptojanin 1
chr11_+_236540	0.24	ENST00000532097.1	PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr5_+_141348721	0.24	ENST00000507163.1 ENST00000394519.1	RNF14	ring finger protein 14
chr17_+_60501228	0.24	ENST00000311506.5	METTL2A	methyltransferase like 2A
chr2_+_27440229	0.23	ENST00000264705.4 ENST00000403525.1	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_+_10092890	0.23	ENST00000253251.8 ENST00000377157.3	UBE4B	ubiquitination factor E4B
chr15_-_50647347	0.23	ENST00000220429.8 ENST00000429662.2	GABPB1	GA binding protein transcription factor, beta subunit 1
chr7_-_102985035	0.23	ENST00000426036.2 ENST00000249270.7 ENST00000454277.1 ENST00000412522.1	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr20_-_35402123	0.23	ENST00000373740.3 ENST00000426836.1 ENST00000373745.3 ENST00000448110.2 ENST00000438549.1 ENST00000447406.1 ENST00000373750.4 ENST00000373734.4	DSN1	DSN1, MIS12 kinetochore complex component
chr12_+_49717019	0.23	ENST00000549275.1 ENST00000551245.1 ENST00000380327.5 ENST00000548311.1 ENST00000550346.1 ENST00000550709.1 ENST00000549534.1 ENST00000257909.3	TROAP	trophinin associated protein
chr4_+_39460620	0.22	ENST00000340169.2 ENST00000261434.3	LIAS	lipoic acid synthetase
chr16_-_67694129	0.22	ENST00000602320.1	ACD	adrenocortical dysplasia homolog (mouse)
chrX_+_129473916	0.22	ENST00000545805.1 ENST00000543953.1 ENST00000218197.5	SLC25A14	solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_+_39460659	0.22	ENST00000513731.1	LIAS	lipoic acid synthetase
chr12_+_5019061	0.22	ENST00000382545.3	KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr2_+_71357434	0.22	ENST00000244230.2	MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr17_-_41277370	0.22	ENST00000476777.1 ENST00000491747.2 ENST00000478531.1 ENST00000477152.1 ENST00000357654.3 ENST00000493795.1 ENST00000493919.1	BRCA1	breast cancer 1, early onset
chr11_-_72145426	0.22	ENST00000535990.1 ENST00000437826.2 ENST00000340729.5	CLPB	ClpB caseinolytic peptidase B homolog (E. coli)
chr11_-_119234876	0.21	ENST00000525735.1	USP2	ubiquitin specific peptidase 2
chr1_-_38019878	0.21	ENST00000296215.6	SNIP1	Smad nuclear interacting protein 1
chr11_+_85955787	0.21	ENST00000528180.1	EED	embryonic ectoderm development
chr3_+_160117418	0.21	ENST00000465903.1 ENST00000485645.1 ENST00000360111.2 ENST00000472991.1 ENST00000467468.1 ENST00000469762.1 ENST00000489573.1 ENST00000462787.1 ENST00000490207.1 ENST00000485867.1	SMC4	structural maintenance of chromosomes 4
chr21_-_34100341	0.21	ENST00000382499.2 ENST00000433931.2	SYNJ1	synaptojanin 1
chr21_+_47743995	0.21	ENST00000359568.5	PCNT	pericentrin
chr2_-_128785688	0.20	ENST00000259234.6	SAP130	Sin3A-associated protein, 130kDa
chr7_-_30544405	0.20	ENST00000409390.1 ENST00000409144.1 ENST00000005374.6 ENST00000409436.1 ENST00000275428.4	GGCT	gamma-glutamylcyclotransferase
chr7_-_152373216	0.20	ENST00000359321.1	XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2
chr11_+_34073269	0.20	ENST00000389645.3	CAPRIN1	cell cycle associated protein 1
chr3_-_10028366	0.20	ENST00000429759.1	EMC3	ER membrane protein complex subunit 3
chrX_-_20159934	0.20	ENST00000379593.1 ENST00000379607.5	EIF1AX	eukaryotic translation initiation factor 1A, X-linked
chr6_+_19837592	0.20	ENST00000378700.3	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr5_+_139781393	0.20	ENST00000360839.2 ENST00000297183.6 ENST00000421134.1 ENST00000394723.3 ENST00000511151.1	ANKHD1	ankyrin repeat and KH domain containing 1
chr9_+_131709966	0.20	ENST00000372577.2	NUP188	nucleoporin 188kDa
chr3_+_179280668	0.20	ENST00000429709.2 ENST00000450518.2 ENST00000392662.1 ENST00000490364.1	ACTL6A	actin-like 6A
chr11_+_237016	0.20	ENST00000352303.5	PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr1_+_161129254	0.20	ENST00000368002.3 ENST00000289865.8 ENST00000479344.1 ENST00000368001.1	USP21	ubiquitin specific peptidase 21
chr1_-_55680762	0.20	ENST00000407756.1 ENST00000294383.6	USP24	ubiquitin specific peptidase 24
chr1_+_10490127	0.20	ENST00000602787.1 ENST00000602296.1 ENST00000400900.2	APITD1 APITD1-CORT	apoptosis-inducing, TAF9-like domain 1 APITD1-CORT readthrough
chr17_-_73781567	0.20	ENST00000586607.1	H3F3B	H3 histone, family 3B (H3.3B)
chr1_-_36615065	0.20	ENST00000373166.3 ENST00000373159.1 ENST00000373162.1	TRAPPC3	trafficking protein particle complex 3
chr4_+_39460689	0.19	ENST00000381846.1	LIAS	lipoic acid synthetase
chr5_+_149737202	0.19	ENST00000451292.1 ENST00000377797.3 ENST00000445265.2 ENST00000323668.7 ENST00000439160.2 ENST00000394269.3 ENST00000427724.2 ENST00000504761.2 ENST00000513346.1 ENST00000515516.1	TCOF1	Treacher Collins-Franceschetti syndrome 1
chr11_-_61734599	0.19	ENST00000532601.1	FTH1	ferritin, heavy polypeptide 1
chr11_-_123525289	0.19	ENST00000392770.2 ENST00000299333.3 ENST00000530277.1	SCN3B	sodium channel, voltage-gated, type III, beta subunit
chr19_-_48673552	0.19	ENST00000536218.1 ENST00000596549.1	LIG1	ligase I, DNA, ATP-dependent
chr2_+_157292933	0.19	ENST00000540309.1	GPD2	glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr6_+_27775899	0.19	ENST00000358739.3	HIST1H2AI	histone cluster 1, H2ai
chr5_-_43313574	0.19	ENST00000325110.6 ENST00000433297.2	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_-_12921270	0.19	ENST00000578071.1 ENST00000426905.3 ENST00000395962.2 ENST00000583371.1 ENST00000338034.4	ELAC2	elaC ribonuclease Z 2
chr1_-_47779762	0.19	ENST00000371877.3 ENST00000360380.3 ENST00000337817.5 ENST00000447475.2	STIL	SCL/TAL1 interrupting locus
chr1_-_227505826	0.19	ENST00000334218.5 ENST00000366766.2 ENST00000366764.2	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr1_-_8939265	0.18	ENST00000489867.1	ENO1	enolase 1, (alpha)
chrX_-_100307043	0.18	ENST00000372939.1 ENST00000372935.1 ENST00000372936.3	TRMT2B	tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr5_+_139493665	0.18	ENST00000331327.3	PURA	purine-rich element binding protein A
chrX_-_100307076	0.18	ENST00000338687.7 ENST00000545398.1 ENST00000372931.5	TRMT2B	tRNA methyltransferase 2 homolog B (S. cerevisiae)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.4	1.1	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.4	1.9	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.4	2.9	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.3	3.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.3	2.5	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.2	0.7	GO:0060381	regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.2	0.7	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	1.2	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2	0.7	GO:0042137	sequestering of neurotransmitter(GO:0042137)
0.2	0.6	GO:0070510	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.2	0.6	GO:0009107	lipoate biosynthetic process(GO:0009107)
0.2	0.6	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.2	0.6	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
0.2	0.6	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.2	1.3	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2	0.7	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.2	0.9	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	0.9	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.9	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.9	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1	0.5	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	1.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.5	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.1	0.8	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	0.7	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.4	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.5	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.1	0.4	GO:1904978	regulation of endosome organization(GO:1904978)
0.1	0.7	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.1	0.5	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	1.0	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.4	GO:0046104	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	0.7	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1	0.4	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	0.2	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1	1.7	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	0.2	GO:0044205	'de novo' UMP biosynthetic process(GO:0044205)
0.1	0.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.4	GO:0051661	maintenance of centrosome location(GO:0051661)
0.1	1.4	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.8	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	0.1	GO:1904815	negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1	0.2	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	0.4	GO:0040031	snRNA modification(GO:0040031)
0.1	0.2	GO:0072660	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.3	GO:0009233	menaquinone metabolic process(GO:0009233)
0.1	0.5	GO:0007144	female meiosis I(GO:0007144)
0.1	0.3	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.1	1.7	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.3	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0046098	hypoxanthine salvage(GO:0043103) guanine metabolic process(GO:0046098)
0.0	0.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	1.4	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.8	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.2	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.4	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.2	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.3	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.0	0.2	GO:0061107	prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.0	0.4	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.6	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.2	GO:0045144	meiotic sister chromatid segregation(GO:0045144)
0.0	1.1	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	0.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.7	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.2	GO:0014029	neural crest formation(GO:0014029)
0.0	0.2	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.0	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0	0.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.2	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.2	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0	0.1	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.2	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.7	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.2	GO:0009642	response to light intensity(GO:0009642)
0.0	0.3	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.2	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.3	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0	1.0	GO:0006342	chromatin silencing(GO:0006342)
0.0	0.5	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0	0.2	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.3	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.7	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.3	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0010666	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.1	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	0.7	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.0	0.4	GO:0051031	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.6	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3	4.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	4.9	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	2.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.1	1.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.1	0.7	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	0.9	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	3.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	1.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.2	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.5	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	2.7	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	2.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	2.2	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.2	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.4	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	3.9	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.6	PID ATR PATHWAY	ATR signaling pathway
0.0	0.4	PID MYC PATHWAY	C-MYC pathway
0.0	1.9	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.8	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.0	PID PLK1 PATHWAY	PLK1 signaling events
0.0	2.1	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.4	GO:0032143	single thymine insertion binding(GO:0032143)
0.3	3.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3	0.8	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.2	1.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.2	0.6	GO:0016992	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.2	1.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.2	0.6	GO:0004170	dUTP diphosphatase activity(GO:0004170)
0.2	0.6	GO:0070025	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2	1.5	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2	0.5	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2	0.9	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.2	0.7	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.7	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	1.0	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.4	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.5	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.7	GO:0051870	methotrexate binding(GO:0051870)
0.1	1.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.5	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.6	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.1	1.0	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.1	3.0	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	0.3	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.7	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.1	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	0.2	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	1.0	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.1	0.4	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.4	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	0.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.6	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.2	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.1	0.4	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.1	0.7	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	1.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	0.5	GO:0003910	DNA ligase (ATP) activity(GO:0003910)
0.0	1.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.4	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.0	0.2	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.2	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.4	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.6	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.5	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.6	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.2	GO:0016416	O-palmitoyltransferase activity(GO:0016416)
0.0	0.7	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.8	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.2	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.7	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.0	GO:0008940	nitrate reductase activity(GO:0008940)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	1.1	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.3	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.5	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.8	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0	0.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.3	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.4	GO:0008173	RNA methyltransferase activity(GO:0008173)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.4	GO:0032301	MutSalpha complex(GO:0032301)
0.3	1.0	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3	3.4	GO:0042555	MCM complex(GO:0042555)
0.3	1.3	GO:0005726	perichromatin fibrils(GO:0005726)
0.2	0.6	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
0.2	1.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.2	2.2	GO:0000800	lateral element(GO:0000800)
0.2	0.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.2	0.6	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.2	0.5	GO:0031523	Myb complex(GO:0031523)
0.1	0.7	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	1.4	GO:0042575	DNA polymerase complex(GO:0042575)
0.1	0.9	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.1	0.4	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	0.1	GO:0032302	MutSbeta complex(GO:0032302)
0.1	0.3	GO:0098536	deuterosome(GO:0098536)
0.1	1.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.1	0.7	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1	0.3	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	1.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.7	GO:0070187	telosome(GO:0070187)
0.1	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.6	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.3	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1	1.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.5	GO:0001739	sex chromatin(GO:0001739)
0.0	0.8	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	2.4	GO:0000786	nucleosome(GO:0000786)
0.0	0.7	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0008043	intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0	0.2	GO:0033063	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.3	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	4.2	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.4	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.3	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	1.2	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.4	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.3	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0043194	axon initial segment(GO:0043194)
0.0	0.9	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.2	GO:0072686	mitotic spindle(GO:0072686)
0.0	0.2	GO:0044232	organelle membrane contact site(GO:0044232)