ISMARA results: ELF3

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ENCODE cell lines, expression (Ernst 2011)

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Results for ELF3_EHF

Z-value: 1.35

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Transcription factors associated with ELF3_EHF

Gene Symbol	Gene ID	Gene Info
ELF3 Ensembl NCBI GeneCards UniProt	ENSG00000163435.11	ELF3
EHF Ensembl NCBI GeneCards UniProt	ENSG00000135373.8	EHF

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ELF3	hg19_v2_chr1_+_201979645_201979721	0.60	1.3e-02	Click!
EHF	hg19_v2_chr11_+_34642656_34642682	0.18	5.1e-01	Click!

Activity profile of ELF3_EHF motif

Sorted Z-values of ELF3_EHF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF3_EHF

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr3_-_79816965	3.76	ENST00000464233.1	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chrX_+_114827818	3.54	ENST00000420625.2	PLS3	plastin 3
chr2_+_138722028	3.35	ENST00000280096.5	HNMT	histamine N-methyltransferase
chr3_-_149095652	2.49	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr14_+_24702073	2.42	ENST00000399440.2	GMPR2	guanosine monophosphate reductase 2
chr6_+_31620191	2.32	ENST00000375918.2 ENST00000375920.4	APOM	apolipoprotein M
chr17_-_79269067	2.29	ENST00000288439.5 ENST00000374759.3	SLC38A10	solute carrier family 38, member 10
chr14_+_24701819	2.26	ENST00000560139.1 ENST00000559910.1	GMPR2	guanosine monophosphate reductase 2
chr2_+_138721850	2.04	ENST00000329366.4 ENST00000280097.3	HNMT	histamine N-methyltransferase
chr14_+_24701628	2.02	ENST00000355299.4 ENST00000559836.1	GMPR2	guanosine monophosphate reductase 2
chr10_+_114135952	1.91	ENST00000356116.1 ENST00000433418.1 ENST00000354273.4	ACSL5	acyl-CoA synthetase long-chain family member 5
chr16_-_11680791	1.90	ENST00000571976.1 ENST00000413364.2	LITAF	lipopolysaccharide-induced TNF factor
chr1_-_146696901	1.75	ENST00000369272.3 ENST00000441068.2	FMO5	flavin containing monooxygenase 5
chr10_+_81838792	1.75	ENST00000372273.3	TMEM254	transmembrane protein 254
chr19_+_16296191	1.74	ENST00000589852.1 ENST00000263384.7 ENST00000588367.1 ENST00000587351.1	FAM32A	family with sequence similarity 32, member A
chr19_+_58694396	1.71	ENST00000326804.4 ENST00000345813.3 ENST00000424679.2	ZNF274	zinc finger protein 274
chr11_-_58345569	1.70	ENST00000528954.1 ENST00000528489.1	LPXN	leupaxin
chr1_-_154946825	1.69	ENST00000368453.4 ENST00000368450.1 ENST00000366442.2	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr5_-_93447333	1.69	ENST00000395965.3 ENST00000505869.1 ENST00000509163.1	FAM172A	family with sequence similarity 172, member A
chr1_-_146697185	1.68	ENST00000533174.1 ENST00000254090.4	FMO5	flavin containing monooxygenase 5
chr20_-_48532019	1.61	ENST00000289431.5	SPATA2	spermatogenesis associated 2
chr2_-_110371720	1.61	ENST00000356688.4	SEPT10	septin 10
chr8_-_80993010	1.55	ENST00000537855.1 ENST00000520527.1 ENST00000517427.1 ENST00000448733.2 ENST00000379097.3	TPD52	tumor protein D52
chr2_-_28113965	1.54	ENST00000302188.3	RBKS	ribokinase
chr15_+_45879534	1.50	ENST00000564080.1 ENST00000562384.1 ENST00000569076.1 ENST00000566753.1	RP11-96O20.4 BLOC1S6	Uncharacterized protein biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr7_-_24797032	1.47	ENST00000409970.1 ENST00000409775.3	DFNA5	deafness, autosomal dominant 5
chr14_+_69865401	1.44	ENST00000556605.1 ENST00000336643.5 ENST00000031146.4	SLC39A9	solute carrier family 39, member 9
chr1_+_40505891	1.43	ENST00000372797.3 ENST00000372802.1 ENST00000449311.1	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr12_-_123201337	1.42	ENST00000528880.2	HCAR3	hydroxycarboxylic acid receptor 3
chr11_-_62389449	1.42	ENST00000534026.1	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_+_69969106	1.39	ENST00000409920.1 ENST00000394295.4 ENST00000536030.1	ANXA4	annexin A4
chr18_-_21166841	1.36	ENST00000269228.5	NPC1	Niemann-Pick disease, type C1
chr11_+_35211429	1.35	ENST00000525688.1 ENST00000278385.6 ENST00000533222.1	CD44	CD44 molecule (Indian blood group)
chr7_+_100770328	1.34	ENST00000223095.4 ENST00000445463.2	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr11_+_35211511	1.34	ENST00000524922.1	CD44	CD44 molecule (Indian blood group)
chr9_+_71736177	1.29	ENST00000606364.1 ENST00000453658.2	TJP2	tight junction protein 2
chr6_-_31620403	1.28	ENST00000451898.1 ENST00000439687.2 ENST00000362049.6 ENST00000424480.1	BAG6	BCL2-associated athanogene 6
chrY_+_2709906	1.26	ENST00000430575.1	RPS4Y1	ribosomal protein S4, Y-linked 1
chrX_+_102631844	1.26	ENST00000372634.1 ENST00000299872.7	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_+_198318147	1.22	ENST00000263960.2	COQ10B	coenzyme Q10 homolog B (S. cerevisiae)
chr6_-_31620455	1.22	ENST00000437771.1 ENST00000404765.2 ENST00000375964.6 ENST00000211379.5	BAG6	BCL2-associated athanogene 6
chr8_-_134309823	1.22	ENST00000414097.2	NDRG1	N-myc downstream regulated 1
chrX_+_54834791	1.16	ENST00000218439.4 ENST00000375058.1 ENST00000375060.1	MAGED2	melanoma antigen family D, 2
chr2_+_110371905	1.15	ENST00000356454.3	SOWAHC	sosondowah ankyrin repeat domain family member C
chrY_+_22918021	1.15	ENST00000288666.5	RPS4Y2	ribosomal protein S4, Y-linked 2
chr12_-_123187890	1.15	ENST00000328880.5	HCAR2	hydroxycarboxylic acid receptor 2
chr8_-_134309335	1.14	ENST00000522890.1 ENST00000323851.7 ENST00000518176.1 ENST00000354944.5 ENST00000537882.1 ENST00000522476.1 ENST00000518066.1 ENST00000521544.1 ENST00000518480.1 ENST00000523892.1	NDRG1	N-myc downstream regulated 1
chrY_+_2709527	1.12	ENST00000250784.8	RPS4Y1	ribosomal protein S4, Y-linked 1
chr16_-_18430593	1.12	ENST00000525596.1	NPIPA8	nuclear pore complex interacting protein family, member A8
chr11_-_119993979	1.11	ENST00000524816.3 ENST00000525327.1	TRIM29	tripartite motif containing 29
chr14_+_74416989	1.10	ENST00000334571.2 ENST00000554920.1	COQ6	coenzyme Q6 monooxygenase
chr17_-_9479128	1.09	ENST00000574431.1	STX8	syntaxin 8
chr2_-_85555086	1.08	ENST00000444342.2 ENST00000409232.3 ENST00000409015.1	TGOLN2	trans-golgi network protein 2
chr3_-_57113314	1.08	ENST00000338458.4 ENST00000468727.1	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr2_-_110371664	1.07	ENST00000545389.1 ENST00000423520.1	SEPT10	septin 10
chr3_-_49395705	1.04	ENST00000419349.1	GPX1	glutathione peroxidase 1
chr6_-_99873145	1.04	ENST00000369239.5 ENST00000438806.1	PNISR	PNN-interacting serine/arginine-rich protein
chr2_-_69870747	1.03	ENST00000409068.1	AAK1	AP2 associated kinase 1
chr8_+_104310661	1.01	ENST00000522566.1	FZD6	frizzled family receptor 6
chr6_+_36853607	1.00	ENST00000480824.2 ENST00000355190.3 ENST00000373685.1	C6orf89	chromosome 6 open reading frame 89
chr2_-_99279928	1.00	ENST00000414521.2	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr16_+_16425734	0.99	ENST00000381497.2	AC138969.4	Protein PKD1P1
chr16_-_25122785	0.98	ENST00000563962.1 ENST00000569920.1	RP11-449H11.1	RP11-449H11.1
chr2_-_85555355	0.95	ENST00000282120.2 ENST00000398263.2	TGOLN2	trans-golgi network protein 2
chr11_+_5710919	0.95	ENST00000379965.3 ENST00000425490.1	TRIM22	tripartite motif containing 22
chr14_+_24702127	0.94	ENST00000557854.1 ENST00000348719.7 ENST00000559104.1 ENST00000456667.3	GMPR2	guanosine monophosphate reductase 2
chr14_+_35761580	0.94	ENST00000553809.1 ENST00000555764.1 ENST00000556506.1	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr11_+_71164149	0.94	ENST00000319023.2	NADSYN1	NAD synthetase 1
chr14_-_24701539	0.93	ENST00000534348.1 ENST00000524927.1 ENST00000250495.5	NEDD8-MDP1 NEDD8	NEDD8-MDP1 readthrough neural precursor cell expressed, developmentally down-regulated 8
chr2_+_71295416	0.92	ENST00000455662.2 ENST00000531934.1	NAGK	N-acetylglucosamine kinase
chr9_-_86571628	0.91	ENST00000376344.3	C9orf64	chromosome 9 open reading frame 64
chr4_+_166128735	0.90	ENST00000226725.6	KLHL2	kelch-like family member 2
chr2_+_71295717	0.90	ENST00000418807.3 ENST00000443872.2	NAGK	N-acetylglucosamine kinase
chr5_+_96079240	0.88	ENST00000515663.1	CAST	calpastatin
chr2_-_238499337	0.88	ENST00000411462.1 ENST00000409822.1	RAB17	RAB17, member RAS oncogene family
chr7_-_100860851	0.88	ENST00000223127.3	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr10_+_81838411	0.87	ENST00000372281.3 ENST00000372277.3 ENST00000372275.1 ENST00000372274.1	TMEM254	transmembrane protein 254
chr19_-_11373128	0.86	ENST00000294618.7	DOCK6	dedicator of cytokinesis 6
chr6_+_53659746	0.86	ENST00000370888.1	LRRC1	leucine rich repeat containing 1
chr14_+_24702099	0.84	ENST00000420554.2	GMPR2	guanosine monophosphate reductase 2
chr17_-_38256973	0.84	ENST00000246672.3	NR1D1	nuclear receptor subfamily 1, group D, member 1
chr13_-_33760216	0.83	ENST00000255486.4	STARD13	StAR-related lipid transfer (START) domain containing 13
chr17_+_41561317	0.83	ENST00000540306.1 ENST00000262415.3 ENST00000605777.1	DHX8	DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr15_+_45879321	0.83	ENST00000220531.3 ENST00000567461.1	BLOC1S6	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr3_-_121468513	0.81	ENST00000494517.1 ENST00000393667.3	GOLGB1	golgin B1
chr1_+_156698234	0.81	ENST00000368218.4 ENST00000368216.4	RRNAD1	ribosomal RNA adenine dimethylase domain containing 1
chr18_+_55816546	0.81	ENST00000435432.2 ENST00000357895.5 ENST00000586263.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_+_113342163	0.80	ENST00000409719.1	CHCHD5	coiled-coil-helix-coiled-coil-helix domain containing 5
chr17_-_39093672	0.80	ENST00000209718.3 ENST00000436344.3 ENST00000485751.1	KRT23	keratin 23 (histone deacetylase inducible)
chr6_+_83073952	0.79	ENST00000543496.1	TPBG	trophoblast glycoprotein
chr6_-_31620149	0.79	ENST00000435080.1 ENST00000375976.4 ENST00000441054.1	BAG6	BCL2-associated athanogene 6
chr12_-_133405288	0.79	ENST00000204726.3	GOLGA3	golgin A3
chr4_-_84035905	0.79	ENST00000311507.4	PLAC8	placenta-specific 8
chr11_-_104840093	0.78	ENST00000417440.2 ENST00000444739.2	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr7_-_111846435	0.78	ENST00000437633.1 ENST00000428084.1	DOCK4	dedicator of cytokinesis 4
chr11_-_73472096	0.78	ENST00000541588.1 ENST00000336083.3 ENST00000540771.1 ENST00000310653.6	RAB6A	RAB6A, member RAS oncogene family
chr16_+_2588012	0.78	ENST00000354836.5 ENST00000389224.3	PDPK1	3-phosphoinositide dependent protein kinase-1
chr4_+_6576895	0.77	ENST00000285599.3 ENST00000504248.1 ENST00000505907.1	MAN2B2	mannosidase, alpha, class 2B, member 2
chr6_-_159421198	0.77	ENST00000252655.1 ENST00000297262.3 ENST00000367069.2	RSPH3	radial spoke 3 homolog (Chlamydomonas)
chr9_-_77703056	0.77	ENST00000376811.1	NMRK1	nicotinamide riboside kinase 1
chr9_-_21974820	0.77	ENST00000579122.1 ENST00000498124.1	CDKN2A	cyclin-dependent kinase inhibitor 2A
chr9_+_116207007	0.77	ENST00000374140.2	RGS3	regulator of G-protein signaling 3
chr3_-_121468602	0.76	ENST00000340645.5	GOLGB1	golgin B1
chr12_+_113344582	0.75	ENST00000202917.5 ENST00000445409.2 ENST00000452357.2	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_+_41770269	0.75	ENST00000378215.4	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr13_-_25086879	0.75	ENST00000381989.3	PARP4	poly (ADP-ribose) polymerase family, member 4
chr16_+_82090028	0.75	ENST00000568090.1	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr17_-_80009650	0.74	ENST00000310496.4	RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_-_238499725	0.74	ENST00000264601.3	RAB17	RAB17, member RAS oncogene family
chr14_-_74417096	0.74	ENST00000286544.3	FAM161B	family with sequence similarity 161, member B
chr9_-_77703115	0.73	ENST00000361092.4 ENST00000376808.4	NMRK1	nicotinamide riboside kinase 1
chr20_-_48532046	0.73	ENST00000543716.1	SPATA2	spermatogenesis associated 2
chr2_+_163200598	0.73	ENST00000437150.2 ENST00000453113.2	GCA	grancalcin, EF-hand calcium binding protein
chr12_+_113344811	0.73	ENST00000551241.1 ENST00000553185.1 ENST00000550689.1	OAS1	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_54198210	0.73	ENST00000607452.1 ENST00000422521.2	ACYP2	acylphosphatase 2, muscle type
chr14_+_35761540	0.72	ENST00000261479.4	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chrX_+_47092314	0.72	ENST00000218348.3	USP11	ubiquitin specific peptidase 11
chr17_+_4843654	0.72	ENST00000575111.1	RNF167	ring finger protein 167
chr17_+_37844331	0.72	ENST00000578199.1 ENST00000406381.2	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr4_-_84035868	0.72	ENST00000426923.2 ENST00000509973.1	PLAC8	placenta-specific 8
chr17_+_79935418	0.72	ENST00000306729.7 ENST00000306739.4	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr15_-_65810042	0.71	ENST00000321147.6	DPP8	dipeptidyl-peptidase 8
chr9_-_34637718	0.71	ENST00000378892.1 ENST00000277010.4	SIGMAR1	sigma non-opioid intracellular receptor 1
chr12_+_57914742	0.71	ENST00000551351.1	MBD6	methyl-CpG binding domain protein 6
chr17_+_79935464	0.71	ENST00000581647.1 ENST00000580534.1 ENST00000579684.1	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr12_-_110888103	0.71	ENST00000426440.1 ENST00000228825.7	ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr16_+_8891670	0.71	ENST00000268261.4 ENST00000539622.1 ENST00000569958.1 ENST00000537352.1	PMM2	phosphomannomutase 2
chr17_+_40118805	0.71	ENST00000591072.1 ENST00000587679.1 ENST00000393888.1 ENST00000441615.2	CNP	2',3'-cyclic nucleotide 3' phosphodiesterase
chr3_-_171528227	0.70	ENST00000356327.5 ENST00000342215.6 ENST00000340989.4 ENST00000351298.4	PLD1	phospholipase D1, phosphatidylcholine-specific
chr15_-_65809581	0.70	ENST00000341861.5	DPP8	dipeptidyl-peptidase 8
chr2_+_163200848	0.70	ENST00000233612.4	GCA	grancalcin, EF-hand calcium binding protein
chr16_+_2802316	0.70	ENST00000301740.8	SRRM2	serine/arginine repetitive matrix 2
chr15_-_65809991	0.69	ENST00000559526.1 ENST00000358939.4 ENST00000560665.1 ENST00000321118.7 ENST00000339244.5 ENST00000300141.6	DPP8	dipeptidyl-peptidase 8
chr2_+_118846008	0.69	ENST00000245787.4	INSIG2	insulin induced gene 2
chr19_-_52598958	0.69	ENST00000594440.1 ENST00000426391.2 ENST00000389534.4	ZNF841	zinc finger protein 841
chr19_+_53836985	0.68	ENST00000601857.1 ENST00000595091.1 ENST00000458035.1	ZNF845	zinc finger protein 845
chr9_+_100174344	0.68	ENST00000422139.2	TDRD7	tudor domain containing 7
chr6_+_37787262	0.68	ENST00000287218.4	ZFAND3	zinc finger, AN1-type domain 3
chr16_+_2587998	0.68	ENST00000441549.3 ENST00000268673.7	PDPK1	3-phosphoinositide dependent protein kinase-1
chr2_-_264024	0.67	ENST00000403712.2 ENST00000356150.5 ENST00000405430.1	SH3YL1	SH3 and SYLF domain containing 1
chr20_-_24973318	0.67	ENST00000447138.1	APMAP	adipocyte plasma membrane associated protein
chr7_-_29234802	0.67	ENST00000449801.1 ENST00000409850.1	CPVL	carboxypeptidase, vitellogenic-like
chr17_+_40118759	0.67	ENST00000393892.3	CNP	2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_-_45927097	0.67	ENST00000340192.7	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr12_-_44200146	0.67	ENST00000395510.2 ENST00000325127.4	TWF1	twinfilin actin-binding protein 1
chr11_+_2920951	0.67	ENST00000347936.2	SLC22A18	solute carrier family 22, member 18
chr13_+_50070491	0.67	ENST00000496612.1 ENST00000357596.3 ENST00000485919.1 ENST00000442195.1	PHF11	PHD finger protein 11
chr8_+_100025476	0.66	ENST00000355155.1 ENST00000357162.2 ENST00000358544.2 ENST00000395996.1 ENST00000441350.2	VPS13B	vacuolar protein sorting 13 homolog B (yeast)
chr19_+_47759716	0.66	ENST00000221922.6	CCDC9	coiled-coil domain containing 9
chr10_-_98031310	0.66	ENST00000427367.2 ENST00000413476.2	BLNK	B-cell linker
chr17_-_42580738	0.66	ENST00000585614.1 ENST00000591680.1 ENST00000434000.1 ENST00000588554.1 ENST00000592154.1	GPATCH8	G patch domain containing 8
chr2_+_71295733	0.65	ENST00000443938.2 ENST00000244204.6	NAGK	N-acetylglucosamine kinase
chr16_-_30366672	0.64	ENST00000305596.3	CD2BP2	CD2 (cytoplasmic tail) binding protein 2
chr13_+_43597269	0.64	ENST00000379221.2	DNAJC15	DnaJ (Hsp40) homolog, subfamily C, member 15
chr1_+_207262627	0.64	ENST00000391923.1	C4BPB	complement component 4 binding protein, beta
chr18_+_55888767	0.64	ENST00000431212.2 ENST00000586268.1 ENST00000587190.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr16_-_11681316	0.63	ENST00000571688.1	LITAF	lipopolysaccharide-induced TNF factor
chr12_-_103310987	0.63	ENST00000307000.2	PAH	phenylalanine hydroxylase
chr20_+_19867150	0.62	ENST00000255006.6	RIN2	Ras and Rab interactor 2
chr6_-_159420780	0.62	ENST00000449822.1	RSPH3	radial spoke 3 homolog (Chlamydomonas)
chr16_+_4784458	0.62	ENST00000590191.1	C16orf71	chromosome 16 open reading frame 71
chr11_+_70244510	0.62	ENST00000346329.3 ENST00000301843.8 ENST00000376561.3	CTTN	cortactin
chr3_+_57541975	0.62	ENST00000487257.1 ENST00000311180.8	PDE12	phosphodiesterase 12
chr17_+_38375574	0.62	ENST00000323571.4 ENST00000585043.1 ENST00000394103.3 ENST00000536600.1	WIPF2	WAS/WASL interacting protein family, member 2
chr20_+_47538357	0.62	ENST00000371917.4	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr4_-_492891	0.62	ENST00000338977.5 ENST00000511833.2	ZNF721	zinc finger protein 721
chr6_-_11382478	0.61	ENST00000397378.3 ENST00000513989.1 ENST00000508546.1 ENST00000504387.1	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr11_+_124492749	0.61	ENST00000531667.1 ENST00000441174.3 ENST00000375005.4	TBRG1	transforming growth factor beta regulator 1
chr1_+_158975744	0.60	ENST00000426592.2	IFI16	interferon, gamma-inducible protein 16
chr2_+_120124497	0.60	ENST00000355857.3 ENST00000535617.1 ENST00000535757.1 ENST00000409094.1 ENST00000311521.4	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr6_+_111580508	0.60	ENST00000368847.4	KIAA1919	KIAA1919
chr17_+_42264322	0.60	ENST00000446571.3 ENST00000357984.3 ENST00000538716.2	TMUB2	transmembrane and ubiquitin-like domain containing 2
chr3_-_123411191	0.60	ENST00000354792.5 ENST00000508240.1	MYLK	myosin light chain kinase
chr6_+_30035307	0.60	ENST00000376765.2 ENST00000376763.1	PPP1R11	protein phosphatase 1, regulatory (inhibitor) subunit 11
chr19_-_51869592	0.60	ENST00000596253.1 ENST00000309244.4	ETFB	electron-transfer-flavoprotein, beta polypeptide
chr4_-_83812402	0.60	ENST00000395310.2	SEC31A	SEC31 homolog A (S. cerevisiae)
chr4_-_83812248	0.59	ENST00000514326.1 ENST00000505434.1 ENST00000503058.1 ENST00000348405.4 ENST00000505984.1 ENST00000513858.1 ENST00000508479.1 ENST00000443462.2 ENST00000508502.1 ENST00000509142.1 ENST00000432794.1 ENST00000448323.1 ENST00000326950.5 ENST00000311785.7	SEC31A	SEC31 homolog A (S. cerevisiae)
chr1_+_52870227	0.59	ENST00000257181.9	PRPF38A	pre-mRNA processing factor 38A
chr11_+_63753883	0.59	ENST00000538426.1 ENST00000543004.1	OTUB1	OTU domain, ubiquitin aldehyde binding 1
chr15_+_45879779	0.59	ENST00000566801.1 ENST00000568816.1 ENST00000565323.1	BLOC1S6	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr3_+_159557637	0.58	ENST00000445224.2	SCHIP1	schwannomin interacting protein 1
chr10_-_50747064	0.58	ENST00000355832.5 ENST00000603152.1 ENST00000447839.2	ERCC6 PGBD3 ERCC6-PGBD3	excision repair cross-complementing rodent repair deficiency, complementation group 6 piggyBac transposable element derived 3 ERCC6-PGBD3 readthrough
chr16_+_67233412	0.58	ENST00000477898.1	ELMO3	engulfment and cell motility 3
chr16_+_2587965	0.58	ENST00000342085.4 ENST00000566659.1	PDPK1	3-phosphoinositide dependent protein kinase-1
chr1_+_207262578	0.58	ENST00000243611.5 ENST00000367076.3	C4BPB	complement component 4 binding protein, beta
chr15_-_90233866	0.57	ENST00000561257.1	PEX11A	peroxisomal biogenesis factor 11 alpha
chr10_-_98031265	0.57	ENST00000224337.5 ENST00000371176.2	BLNK	B-cell linker
chr2_-_220435963	0.56	ENST00000373876.1 ENST00000404537.1 ENST00000603926.1 ENST00000373873.4 ENST00000289656.3	OBSL1	obscurin-like 1
chr8_+_132916318	0.56	ENST00000254624.5 ENST00000522709.1	EFR3A	EFR3 homolog A (S. cerevisiae)
chr15_+_77287426	0.55	ENST00000558012.1 ENST00000267939.5 ENST00000379595.3	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr2_-_122407097	0.54	ENST00000409078.3	CLASP1	cytoplasmic linker associated protein 1
chrX_+_69353284	0.54	ENST00000342206.6 ENST00000356413.4	IGBP1	immunoglobulin (CD79A) binding protein 1
chr11_-_119993734	0.54	ENST00000533302.1	TRIM29	tripartite motif containing 29
chr16_+_15068955	0.54	ENST00000396410.4 ENST00000569715.1 ENST00000450288.2	PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr7_+_99613212	0.53	ENST00000426572.1 ENST00000535170.1	ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr4_+_2813946	0.53	ENST00000442312.2	SH3BP2	SH3-domain binding protein 2
chr19_+_45542295	0.53	ENST00000221455.3 ENST00000391953.4 ENST00000588936.1	CLASRP	CLK4-associating serine/arginine rich protein
chr11_-_75236867	0.52	ENST00000376282.3 ENST00000336898.3	GDPD5	glycerophosphodiester phosphodiesterase domain containing 5
chr11_+_22688150	0.52	ENST00000454584.2	GAS2	growth arrest-specific 2
chr19_-_53758094	0.52	ENST00000601828.1 ENST00000598513.1 ENST00000599012.1 ENST00000333952.4 ENST00000598806.1	ZNF677	zinc finger protein 677

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.5	GO:1902560	GMP reductase complex(GO:1902560)
0.8	3.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.8	2.3	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.4	2.5	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.4	2.7	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4	2.2	GO:0070435	Shc-EGFR complex(GO:0070435)
0.3	0.8	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	0.6	GO:0005879	axonemal microtubule(GO:0005879)
0.2	1.3	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	0.8	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.2	2.8	GO:0031083	BLOC-1 complex(GO:0031083)
0.2	0.5	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.1	0.7	GO:1990393	3M complex(GO:1990393)
0.1	1.7	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.1	0.8	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	1.1	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	1.5	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.1	0.7	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	1.2	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.0	GO:0097413	Lewy body(GO:0097413)
0.1	0.5	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	1.4	GO:0005771	multivesicular body(GO:0005771)
0.1	0.6	GO:0061689	tricellular tight junction(GO:0061689)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.6	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.2	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1	0.7	GO:0033391	chromatoid body(GO:0033391)
0.1	0.5	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.9	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	1.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.7	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	0.2	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	1.8	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	3.6	GO:0005801	cis-Golgi network(GO:0005801)
0.1	0.3	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
0.1	0.6	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	1.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	4.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.4	GO:0033269	internode region of axon(GO:0033269)
0.1	0.6	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.1	1.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	3.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.3	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.6	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	2.2	GO:0002102	podosome(GO:0002102)
0.0	0.5	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.6	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.9	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.0	4.4	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0000799	nuclear condensin complex(GO:0000799)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	5.5	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.2	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.5	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.6	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0036128	CatSper complex(GO:0036128)
0.0	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0031085	BLOC-3 complex(GO:0031085)
0.0	0.2	GO:0070847	core mediator complex(GO:0070847)
0.0	0.2	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.4	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0032010	phagolysosome(GO:0032010)
0.0	0.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0005953	CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.0	0.2	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	1.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	2.2	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.6	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.8	GO:0032420	stereocilium(GO:0032420)
0.0	0.3	GO:0090543	Flemming body(GO:0090543)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.0	GO:1990769	proximal neuron projection(GO:1990769)
0.0	2.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.7	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0097165	nuclear stress granule(GO:0097165)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0097361	CIA complex(GO:0097361)
0.0	0.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.0	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.0	0.1	GO:0005902	microvillus(GO:0005902)
0.0	0.6	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	2.0	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	1.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.4	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.1	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.4	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.9	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.8	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.1	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	2.2	GO:0001726	ruffle(GO:0001726)
0.0	1.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	2.4	GO:0005741	mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0032449	CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.0	0.7	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.9	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.9	GO:0044309	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.1	GO:0005923	bicellular tight junction(GO:0005923)
0.0	3.6	GO:0030424	axon(GO:0030424)
0.0	1.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.4	GO:0005881	cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	4.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.0	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	0.2	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	2.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	1.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.7	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	1.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	4.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	1.0	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.5	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.5	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	7.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.6	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	2.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.5	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	1.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	1.4	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.4	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	1.9	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	1.0	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	2.1	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	2.1	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.8	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	1.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	2.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.7	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	4.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	2.7	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	0.3	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	3.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	2.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	1.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	3.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.8	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	2.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.7	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.7	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	2.6	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.9	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.8	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.9	5.4	GO:0001692	histamine metabolic process(GO:0001692)
0.8	3.3	GO:1904327	maintenance of unfolded protein(GO:0036506) protein localization to cytosolic proteasome complex(GO:1904327) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.6	2.5	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.6	2.3	GO:0034445	regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.5	1.5	GO:0006014	D-ribose metabolic process(GO:0006014)
0.4	1.3	GO:2000097	chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3	2.7	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3	1.6	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3	8.5	GO:0043101	purine-containing compound salvage(GO:0043101)
0.3	0.9	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3	1.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3	0.8	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.3	1.1	GO:0044375	regulation of peroxisome size(GO:0044375)
0.3	1.0	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.2	0.7	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.2	1.9	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2	1.4	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.2	1.2	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.2	0.7	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.2	1.1	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2	1.3	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.2	3.5	GO:0051639	actin filament network formation(GO:0051639)
0.2	2.4	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.2	3.5	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2	2.0	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2	0.8	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.2	1.3	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	1.5	GO:0006013	mannose metabolic process(GO:0006013)
0.2	0.6	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2	0.2	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.2	0.9	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	2.0	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.2	0.5	GO:0097359	UDP-glucosylation(GO:0097359)
0.2	1.2	GO:0070294	renal sodium ion absorption(GO:0070294)
0.2	0.5	GO:0006097	glyoxylate cycle(GO:0006097)
0.2	1.3	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.2	0.8	GO:0036369	transcription factor catabolic process(GO:0036369)
0.2	0.5	GO:1901420	negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.2	0.3	GO:0003285	septum secundum development(GO:0003285)
0.2	0.9	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	0.5	GO:1905224	clathrin-coated pit assembly(GO:1905224)
0.1	2.8	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.7	GO:0018125	peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	0.4	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.1	0.8	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.1	1.2	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.7	GO:0030047	actin modification(GO:0030047)
0.1	0.7	GO:0035936	testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1	1.2	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.1	0.4	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1	0.5	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.2	GO:0018282	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1	0.7	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.5	GO:0006114	glycerol biosynthetic process(GO:0006114) response to methionine(GO:1904640)
0.1	0.5	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.6	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	0.4	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.3	GO:0006522	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.1	0.6	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.7	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.1	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1	0.1	GO:0090164	asymmetric Golgi ribbon formation(GO:0090164)
0.1	0.3	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.1	0.3	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1	2.7	GO:0006895	Golgi to endosome transport(GO:0006895)
0.1	0.6	GO:1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1	2.7	GO:0009435	NAD biosynthetic process(GO:0009435)
0.1	0.4	GO:0009233	menaquinone metabolic process(GO:0009233) menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1	1.2	GO:2000111	senescence-associated heterochromatin focus assembly(GO:0035986) positive regulation of macrophage apoptotic process(GO:2000111)
0.1	0.3	GO:0061055	myotome development(GO:0061055)
0.1	0.3	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1	0.3	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.1	0.9	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1	0.4	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.6	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	0.7	GO:1902915	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.7	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.3	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.1	0.5	GO:0071105	response to interleukin-11(GO:0071105)
0.1	0.3	GO:0051125	regulation of actin nucleation(GO:0051125)
0.1	0.3	GO:0002585	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1	0.4	GO:0097010	eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1	1.3	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	0.2	GO:2000182	regulation of progesterone biosynthetic process(GO:2000182)
0.1	0.7	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.3	GO:1902846	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	0.8	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	1.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.7	GO:0046618	drug export(GO:0046618)
0.1	0.6	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.2	GO:0072716	response to actinomycin D(GO:0072716)
0.1	3.0	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1	0.6	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	0.2	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	0.2	GO:2000439	positive regulation of monocyte extravasation(GO:2000439)
0.1	0.2	GO:1900195	spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.1	0.7	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.8	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.2	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	0.2	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1	1.8	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.3	GO:0042737	drug catabolic process(GO:0042737)
0.1	0.1	GO:0060920	atrioventricular node development(GO:0003162) cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.1	0.1	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.1	0.2	GO:0036071	N-glycan fucosylation(GO:0036071)
0.1	0.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1	0.5	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.5	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	1.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.5	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.3	GO:0042335	cuticle development(GO:0042335)
0.1	1.0	GO:0036109	alpha-linolenic acid metabolic process(GO:0036109)
0.1	0.2	GO:0052053	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1	0.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.3	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.1	0.3	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1	0.7	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.4	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1	0.2	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1	0.2	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.1	0.6	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.2	GO:0070541	response to platinum ion(GO:0070541)
0.1	0.5	GO:0042908	xenobiotic transport(GO:0042908)
0.1	1.4	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1	2.0	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1	1.3	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.3	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.1	0.4	GO:1903232	melanosome assembly(GO:1903232)
0.1	1.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.3	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.1	0.7	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.3	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.7	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.1	0.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.2	GO:2001193	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1	0.7	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	0.5	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.2	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	0.9	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.4	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.4	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.7	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.3	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0	7.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0043309	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.0	0.2	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.5	GO:0045023	G0 to G1 transition(GO:0045023)
0.0	0.3	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.2	GO:1903911	positive regulation of receptor clustering(GO:1903911)
0.0	0.6	GO:0006559	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.7	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.5	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	1.3	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.2	GO:0019348	dolichol metabolic process(GO:0019348)
0.0	0.6	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.4	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	2.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.5	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.1	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0	0.4	GO:0015846	polyamine transport(GO:0015846)
0.0	0.2	GO:0036159	inner dynein arm assembly(GO:0036159)
0.0	0.2	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0	0.2	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.5	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.0	0.3	GO:0090042	tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	1.8	GO:0060113	inner ear receptor cell differentiation(GO:0060113)
0.0	0.7	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.4	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.1	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:1900138	negative regulation of icosanoid secretion(GO:0032304) negative regulation of phospholipase A2 activity(GO:1900138)
0.0	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:1902309	regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.6	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0061110	dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0038155	interleukin-23-mediated signaling pathway(GO:0038155)
0.0	0.4	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0002396	MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0	1.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0045229	cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0	0.4	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.6	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0036216	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.4	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:2000537	regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0	0.1	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0	1.0	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.2	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	1.6	GO:0031529	ruffle organization(GO:0031529)
0.0	0.2	GO:0070560	protein secretion by platelet(GO:0070560)
0.0	0.1	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.4	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	1.3	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.7	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.0	0.1	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0	0.1	GO:0097338	response to clozapine(GO:0097338)
0.0	0.1	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.0	1.5	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	1.3	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	1.2	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:1900193	regulation of oocyte maturation(GO:1900193)
0.0	0.2	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.5	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.5	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.9	GO:0070206	protein trimerization(GO:0070206)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.3	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0019242	methylglyoxal biosynthetic process(GO:0019242)
0.0	0.0	GO:0097026	dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0	0.0	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.2	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.0	GO:0055099	detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.0	0.8	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.2	GO:1904903	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.2	GO:2000772	regulation of cellular senescence(GO:2000772)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.6	GO:0050482	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511) stress granule assembly(GO:0034063)
0.0	0.5	GO:0097421	liver regeneration(GO:0097421)
0.0	0.2	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.1	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.5	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.2	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0	0.1	GO:0035865	cellular response to potassium ion(GO:0035865)
0.0	0.3	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.4	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.3	GO:0061436	establishment of skin barrier(GO:0061436)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.8	GO:0006901	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:2000360	negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.3	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.0	0.0	GO:0090487	toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0	0.6	GO:0051972	regulation of telomerase activity(GO:0051972)
0.0	0.2	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.1	GO:0070236	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.6	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.3	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.5	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.0	0.1	GO:0019249	lactate biosynthetic process(GO:0019249)
0.0	1.6	GO:0007030	Golgi organization(GO:0007030)
0.0	0.3	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.2	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.2	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.6	GO:1901998	toxin transport(GO:1901998)
0.0	0.5	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.0	0.1	GO:1903236	regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.0	GO:1902573	positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0	0.2	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.2	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	1.7	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.0	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.0	0.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0	1.3	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0042177	negative regulation of protein catabolic process(GO:0042177)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.3	GO:0035036	sperm-egg recognition(GO:0035036)
0.0	0.5	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	8.5	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.8	2.5	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.7	2.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.6	3.8	GO:0008046	axon guidance receptor activity(GO:0008046)
0.5	1.4	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4	3.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4	1.5	GO:0050262	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.3	1.3	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.3	2.2	GO:0048408	epidermal growth factor binding(GO:0048408)
0.3	1.2	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.3	0.9	GO:0033823	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.2	1.4	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2	0.8	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2	2.0	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2	3.6	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.2	1.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	0.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	1.3	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2	0.9	GO:0004359	glutaminase activity(GO:0004359)
0.2	0.7	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2	1.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.2	0.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2	0.5	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.2	0.5	GO:0045322	unmethylated CpG binding(GO:0045322)
0.2	0.5	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2	0.5	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2	0.5	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2	0.6	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.6	GO:0030305	beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1	0.7	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	1.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.5	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.7	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.1	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.7	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.7	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.4	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.7	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0004803	transposase activity(GO:0004803)
0.1	1.9	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	4.0	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.3	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.1	0.3	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1	0.5	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1	2.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	1.4	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	0.3	GO:0032090	Pyrin domain binding(GO:0032090)
0.1	0.4	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.1	1.0	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.9	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	2.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	0.3	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.1	0.2	GO:0015039	ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1	0.4	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0004515	nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	0.5	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.1	1.9	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.2	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.3	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.1	0.5	GO:0015232	heme transporter activity(GO:0015232)
0.1	0.3	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	1.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	1.8	GO:0071949	FAD binding(GO:0071949)
0.1	0.9	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	0.9	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.6	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.1	0.7	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1	0.3	GO:0098821	BMP receptor activity(GO:0098821)
0.1	0.3	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.7	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.3	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.8	GO:0050700	CARD domain binding(GO:0050700)
0.1	1.6	GO:0015248	sterol transporter activity(GO:0015248)
0.1	0.4	GO:0031386	protein tag(GO:0031386)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.3	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	0.2	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1	0.8	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	0.8	GO:0001222	transcription corepressor binding(GO:0001222)
0.1	0.5	GO:0046790	virion binding(GO:0046790)
0.1	0.3	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	5.0	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.1	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.6	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.0	0.7	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.5	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	1.5	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.4	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	1.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.6	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.2	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.7	GO:0008494	translation activator activity(GO:0008494)
0.0	0.6	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0039552	RIG-I binding(GO:0039552)
0.0	1.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.4	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.8	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.4	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	1.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.6	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.5	GO:0008527	taste receptor activity(GO:0008527)
0.0	2.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.4	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0043532	angiostatin binding(GO:0043532)
0.0	0.5	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
0.0	0.6	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	1.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.6	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	1.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0004662	CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0	0.1	GO:0042019	interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0	0.3	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.2	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.0	GO:0086062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0	0.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	2.1	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.0	1.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.6	GO:0045503	dynein light chain binding(GO:0045503)
0.0	1.4	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	1.6	GO:0016209	antioxidant activity(GO:0016209)
0.0	1.6	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0004347	glucose-6-phosphate isomerase activity(GO:0004347)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	3.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	4.9	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	1.0	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.4	GO:0015929	hexosaminidase activity(GO:0015929)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	1.9	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0002161	aminoacyl-tRNA editing activity(GO:0002161)
0.0	4.3	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.4	GO:0008483	transaminase activity(GO:0008483)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.4	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.6	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.1	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.3	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.0	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.7	GO:0048306	calcium-dependent protein binding(GO:0048306)

Results for ELF3_EHF

Z-value: 1.35

Motif logo

Transcription factors associated with ELF3_EHF

Activity-expression correlation:

Activity profile of ELF3_EHF motif

Sorted Z-values of ELF3_EHF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF3_EHF

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Gene overrepresentation in C2:CP:REACTOME category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in biological_process category:

Gene overrepresentation in molecular_function category: