ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
EMX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000135638.9	EMX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EMX1	hg19_v2_chr2_+_73144604_73144654	-0.11	6.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr4_+_169418195	3.96	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr11_-_111794446	3.57	ENST00000527950.1	CRYAB	crystallin, alpha B
chr8_-_49833978	3.00	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr4_-_143226979	2.97	ENST00000514525.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_-_13835147	2.82	ENST00000493677.1 ENST00000355135.2	GPM6B	glycoprotein M6B
chr1_-_151965048	2.76	ENST00000368809.1	S100A10	S100 calcium binding protein A10
chr5_+_135394840	2.69	ENST00000503087.1	TGFBI	transforming growth factor, beta-induced, 68kDa
chr12_-_91546926	2.46	ENST00000550758.1	DCN	decorin
chr12_+_81110684	2.31	ENST00000228644.3	MYF5	myogenic factor 5
chr4_-_143227088	2.24	ENST00000511838.1	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_-_49834299	2.20	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr5_+_125758865	2.20	ENST00000542322.1 ENST00000544396.1	GRAMD3	GRAM domain containing 3
chr13_-_38172863	2.18	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN	periostin, osteoblast specific factor
chr5_+_125758813	2.15	ENST00000285689.3 ENST00000515200.1	GRAMD3	GRAM domain containing 3
chr4_+_169418255	1.97	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr13_+_73632897	1.91	ENST00000377687.4	KLF5	Kruppel-like factor 5 (intestinal)
chr3_-_151034734	1.88	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr19_-_51522955	1.81	ENST00000358789.3	KLK10	kallikrein-related peptidase 10
chr1_-_68698222	1.64	ENST00000370976.3 ENST00000354777.2 ENST00000262348.4 ENST00000540432.1	WLS	wntless Wnt ligand secretion mediator
chr7_+_130126165	1.63	ENST00000427521.1 ENST00000416162.2 ENST00000378576.4	MEST	mesoderm specific transcript
chr13_-_110438914	1.59	ENST00000375856.3	IRS2	insulin receptor substrate 2
chr5_+_36608422	1.58	ENST00000381918.3	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_130126012	1.55	ENST00000341441.5	MEST	mesoderm specific transcript
chr12_+_26348246	1.51	ENST00000422622.2	SSPN	sarcospan
chr3_+_158991025	1.49	ENST00000337808.6	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr12_-_50616382	1.48	ENST00000552783.1	LIMA1	LIM domain and actin binding 1
chr12_-_53012343	1.46	ENST00000305748.3	KRT73	keratin 73
chr1_-_95391315	1.45	ENST00000545882.1 ENST00000415017.1	CNN3	calponin 3, acidic
chr10_-_93392811	1.38	ENST00000238994.5	PPP1R3C	protein phosphatase 1, regulatory subunit 3C
chr7_-_107642348	1.36	ENST00000393561.1	LAMB1	laminin, beta 1
chr3_-_123339343	1.31	ENST00000578202.1	MYLK	myosin light chain kinase
chr18_-_21891460	1.25	ENST00000357041.4	OSBPL1A	oxysterol binding protein-like 1A
chr8_+_32579341	1.23	ENST00000519240.1 ENST00000539990.1	NRG1	neuregulin 1
chr2_-_190927447	1.23	ENST00000260950.4	MSTN	myostatin
chr17_-_39743139	1.22	ENST00000167586.6	KRT14	keratin 14
chr5_-_82969405	1.20	ENST00000510978.1	HAPLN1	hyaluronan and proteoglycan link protein 1
chr3_+_158787041	1.17	ENST00000471575.1 ENST00000476809.1 ENST00000485419.1	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr12_-_28123206	1.13	ENST00000542963.1 ENST00000535992.1	PTHLH	parathyroid hormone-like hormone
chr6_+_151646800	1.09	ENST00000354675.6	AKAP12	A kinase (PRKA) anchor protein 12
chr10_-_5046042	1.08	ENST00000421196.3 ENST00000455190.1	AKR1C2	aldo-keto reductase family 1, member C2
chr5_+_53751445	1.07	ENST00000302005.1	HSPB3	heat shock 27kDa protein 3
chr18_+_3447572	1.05	ENST00000548489.2	TGIF1	TGFB-induced factor homeobox 1
chr17_-_7307358	1.03	ENST00000576017.1 ENST00000302422.3 ENST00000535512.1	TMEM256 TMEM256-PLSCR3	transmembrane protein 256 TMEM256-PLSCR3 readthrough (NMD candidate)
chr2_-_179672142	1.02	ENST00000342992.6 ENST00000360870.5 ENST00000460472.2 ENST00000589042.1 ENST00000591111.1 ENST00000342175.6 ENST00000359218.5	TTN	titin
chrX_-_106243451	0.99	ENST00000355610.4 ENST00000535534.1	MORC4	MORC family CW-type zinc finger 4
chr18_-_33702078	0.97	ENST00000586829.1	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chr18_-_33709268	0.93	ENST00000269187.5 ENST00000590986.1 ENST00000440549.2	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chr12_-_28122980	0.92	ENST00000395868.3 ENST00000534890.1	PTHLH	parathyroid hormone-like hormone
chr12_+_26348429	0.87	ENST00000242729.2	SSPN	sarcospan
chr3_+_35722487	0.86	ENST00000441454.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr14_-_70883708	0.85	ENST00000256366.4	SYNJ2BP	synaptojanin 2 binding protein
chr3_-_99595037	0.85	ENST00000383694.2	FILIP1L	filamin A interacting protein 1-like
chr8_+_70404996	0.85	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr3_-_99594948	0.84	ENST00000471562.1 ENST00000495625.2	FILIP1L	filamin A interacting protein 1-like
chr2_-_208031943	0.83	ENST00000421199.1 ENST00000457962.1	KLF7	Kruppel-like factor 7 (ubiquitous)
chr20_+_60174827	0.80	ENST00000543233.1	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr16_+_57279004	0.80	ENST00000219204.3	ARL2BP	ADP-ribosylation factor-like 2 binding protein
chr17_-_10325261	0.76	ENST00000403437.2	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr4_-_186696425	0.76	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr5_+_174151536	0.75	ENST00000239243.6 ENST00000507785.1	MSX2	msh homeobox 2
chr1_+_202317815	0.70	ENST00000608999.1 ENST00000336894.4 ENST00000480184.1	PPP1R12B	protein phosphatase 1, regulatory subunit 12B
chr1_+_84609944	0.70	ENST00000370685.3	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr2_+_234627424	0.67	ENST00000373409.3	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr12_+_54378923	0.66	ENST00000303460.4	HOXC10	homeobox C10
chr10_+_17270214	0.65	ENST00000544301.1	VIM	vimentin
chr5_-_95297534	0.65	ENST00000513343.1 ENST00000431061.2	ELL2	elongation factor, RNA polymerase II, 2
chr1_-_242162375	0.64	ENST00000357246.3	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma
chr11_-_129062093	0.63	ENST00000310343.9	ARHGAP32	Rho GTPase activating protein 32
chr16_-_53737722	0.62	ENST00000569716.1 ENST00000562588.1 ENST00000562230.1 ENST00000379925.3 ENST00000563746.1 ENST00000568653.3	RPGRIP1L	RPGRIP1-like
chr12_-_85306594	0.62	ENST00000266682.5	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr16_-_66764119	0.62	ENST00000569320.1	DYNC1LI2	dynein, cytoplasmic 1, light intermediate chain 2
chr6_-_109777128	0.61	ENST00000358807.3 ENST00000358577.3	MICAL1	microtubule associated monooxygenase, calponin and LIM domain containing 1
chr2_-_207082748	0.60	ENST00000407325.2 ENST00000411719.1	GPR1	G protein-coupled receptor 1
chr17_-_63822563	0.58	ENST00000317442.8	CEP112	centrosomal protein 112kDa
chr3_+_111717600	0.57	ENST00000273368.4	TAGLN3	transgelin 3
chr9_-_107690420	0.56	ENST00000423487.2 ENST00000374733.1 ENST00000374736.3	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1
chr4_+_41614909	0.56	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1	LIM and calponin homology domains 1
chr6_-_91296602	0.54	ENST00000369325.3 ENST00000369327.3	MAP3K7	mitogen-activated protein kinase kinase kinase 7
chr10_-_127505167	0.54	ENST00000368786.1	UROS	uroporphyrinogen III synthase
chr1_+_225600404	0.53	ENST00000366845.2	AC092811.1	AC092811.1
chr16_-_53737795	0.53	ENST00000262135.4 ENST00000564374.1 ENST00000566096.1	RPGRIP1L	RPGRIP1-like
chr21_-_43346790	0.53	ENST00000329623.7	C2CD2	C2 calcium-dependent domain containing 2
chr6_-_91296737	0.52	ENST00000369332.3 ENST00000369329.3	MAP3K7	mitogen-activated protein kinase kinase kinase 7
chr12_+_15699286	0.52	ENST00000442921.2 ENST00000542557.1 ENST00000445537.2 ENST00000544244.1	PTPRO	protein tyrosine phosphatase, receptor type, O
chr3_-_46000064	0.50	ENST00000433878.1	FYCO1	FYVE and coiled-coil domain containing 1
chr3_+_35721106	0.50	ENST00000474696.1 ENST00000412048.1 ENST00000396482.2 ENST00000432682.1	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr3_+_111717511	0.50	ENST00000478951.1 ENST00000393917.2	TAGLN3	transgelin 3
chr1_+_152881014	0.49	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr8_+_98900132	0.49	ENST00000520016.1	MATN2	matrilin 2
chr5_-_16916624	0.49	ENST00000513882.1	MYO10	myosin X
chr1_+_210501589	0.49	ENST00000413764.2 ENST00000541565.1	HHAT	hedgehog acyltransferase
chr3_+_130745688	0.49	ENST00000510769.1 ENST00000429253.2 ENST00000356918.4 ENST00000510688.1 ENST00000511262.1 ENST00000383366.4	NEK11	NIMA-related kinase 11
chr4_+_70796784	0.46	ENST00000246891.4 ENST00000444405.3	CSN1S1	casein alpha s1
chr14_+_74034310	0.46	ENST00000538782.1	ACOT2	acyl-CoA thioesterase 2
chr2_-_217560248	0.45	ENST00000233813.4	IGFBP5	insulin-like growth factor binding protein 5
chr18_-_61329118	0.45	ENST00000332821.8 ENST00000283752.5	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr6_-_46293378	0.45	ENST00000330430.6	RCAN2	regulator of calcineurin 2
chr5_-_95297678	0.44	ENST00000237853.4	ELL2	elongation factor, RNA polymerase II, 2
chr3_+_111718036	0.44	ENST00000455401.2	TAGLN3	transgelin 3
chr1_-_68698197	0.42	ENST00000370973.2 ENST00000370971.1	WLS	wntless Wnt ligand secretion mediator
chr19_+_13049413	0.42	ENST00000316448.5 ENST00000588454.1	CALR	calreticulin
chr1_-_173174681	0.42	ENST00000367718.1	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr11_-_104827425	0.40	ENST00000393150.3	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr2_+_109237717	0.40	ENST00000409441.1	LIMS1	LIM and senescent cell antigen-like domains 1
chr6_+_39760129	0.40	ENST00000274867.4	DAAM2	dishevelled associated activator of morphogenesis 2
chr1_-_21377383	0.39	ENST00000374935.3	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr8_+_105352050	0.39	ENST00000297581.2	DCSTAMP	dendrocyte expressed seven transmembrane protein
chr6_-_100912785	0.39	ENST00000369208.3	SIM1	single-minded family bHLH transcription factor 1
chr19_-_7968427	0.38	ENST00000539278.1	AC010336.1	Uncharacterized protein
chr13_-_36050819	0.38	ENST00000379919.4	MAB21L1	mab-21-like 1 (C. elegans)
chr9_+_26956371	0.37	ENST00000380062.5 ENST00000518614.1	IFT74	intraflagellar transport 74 homolog (Chlamydomonas)
chr4_-_10686475	0.36	ENST00000226951.6	CLNK	cytokine-dependent hematopoietic cell linker
chr7_-_143599207	0.36	ENST00000355951.2 ENST00000479870.1 ENST00000478172.1	FAM115A	family with sequence similarity 115, member A
chr10_+_5005598	0.36	ENST00000442997.1	AKR1C1	aldo-keto reductase family 1, member C1
chr15_+_62853562	0.35	ENST00000561311.1	TLN2	talin 2
chr7_-_27169801	0.34	ENST00000511914.1	HOXA4	homeobox A4
chr17_-_7145475	0.34	ENST00000571129.1 ENST00000571253.1 ENST00000573928.1	GABARAP	GABA(A) receptor-associated protein
chr2_-_86850949	0.33	ENST00000237455.4	RNF103	ring finger protein 103
chr12_-_10959892	0.32	ENST00000240615.2	TAS2R8	taste receptor, type 2, member 8
chr5_-_9630463	0.32	ENST00000382492.2	TAS2R1	taste receptor, type 2, member 1
chr2_-_145277569	0.31	ENST00000303660.4	ZEB2	zinc finger E-box binding homeobox 2
chr6_-_111927449	0.31	ENST00000368761.5 ENST00000392556.4 ENST00000340026.6	TRAF3IP2	TRAF3 interacting protein 2
chr18_+_46065393	0.31	ENST00000256413.3	CTIF	CBP80/20-dependent translation initiation factor
chr7_+_12727250	0.30	ENST00000404894.1	ARL4A	ADP-ribosylation factor-like 4A
chr1_-_48937821	0.30	ENST00000396199.3	SPATA6	spermatogenesis associated 6
chr1_-_94586651	0.28	ENST00000535735.1 ENST00000370225.3	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr11_+_77532233	0.28	ENST00000525409.1	AAMDC	adipogenesis associated, Mth938 domain containing
chr5_+_66300446	0.28	ENST00000261569.7	MAST4	microtubule associated serine/threonine kinase family member 4
chr6_+_52535878	0.28	ENST00000211314.4	TMEM14A	transmembrane protein 14A
chr20_+_18488137	0.27	ENST00000450074.1 ENST00000262544.2 ENST00000336714.3 ENST00000377475.3	SEC23B	Sec23 homolog B (S. cerevisiae)
chr17_+_79650962	0.27	ENST00000329138.4	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_48937838	0.27	ENST00000371847.3	SPATA6	spermatogenesis associated 6
chr5_-_176889381	0.26	ENST00000393563.4 ENST00000512501.1	DBN1	drebrin 1
chr16_-_11036300	0.26	ENST00000331808.4	DEXI	Dexi homolog (mouse)
chr5_-_148929848	0.26	ENST00000504676.1 ENST00000515435.1	CSNK1A1	casein kinase 1, alpha 1
chr2_-_1629176	0.26	ENST00000366424.2	AC144450.2	AC144450.2
chr11_-_104905840	0.25	ENST00000526568.1 ENST00000393136.4 ENST00000531166.1 ENST00000534497.1 ENST00000527979.1 ENST00000446369.1 ENST00000353247.5 ENST00000528974.1 ENST00000533400.1 ENST00000525825.1 ENST00000436863.3	CASP1	caspase 1, apoptosis-related cysteine peptidase
chr18_+_56530136	0.25	ENST00000591083.1	ZNF532	zinc finger protein 532
chr5_+_115177178	0.25	ENST00000316788.7	AP3S1	adaptor-related protein complex 3, sigma 1 subunit
chr7_-_100860851	0.25	ENST00000223127.3	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr14_-_78083112	0.25	ENST00000216484.2	SPTLC2	serine palmitoyltransferase, long chain base subunit 2
chrX_-_14047996	0.24	ENST00000380523.4 ENST00000398355.3	GEMIN8	gem (nuclear organelle) associated protein 8
chr10_-_71169031	0.24	ENST00000373307.1	TACR2	tachykinin receptor 2
chr13_-_44735393	0.24	ENST00000400419.1	SMIM2	small integral membrane protein 2
chr19_+_49990811	0.24	ENST00000391857.4 ENST00000467825.2	RPL13A	ribosomal protein L13a
chrX_+_78003204	0.24	ENST00000435339.3 ENST00000514744.1	LPAR4	lysophosphatidic acid receptor 4
chr19_-_58951496	0.24	ENST00000254166.3	ZNF132	zinc finger protein 132
chr8_+_22424551	0.23	ENST00000523348.1	SORBS3	sorbin and SH3 domain containing 3
chr3_-_151047327	0.23	ENST00000325602.5	P2RY13	purinergic receptor P2Y, G-protein coupled, 13
chr11_-_128894053	0.22	ENST00000392657.3	ARHGAP32	Rho GTPase activating protein 32
chr11_-_118134997	0.22	ENST00000278937.2	MPZL2	myelin protein zero-like 2
chr10_-_28571015	0.22	ENST00000375719.3 ENST00000375732.1	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_10978957	0.22	ENST00000240619.2	TAS2R10	taste receptor, type 2, member 10
chrX_+_46696372	0.21	ENST00000218340.3	RP2	retinitis pigmentosa 2 (X-linked recessive)
chr18_+_616672	0.21	ENST00000338387.7	CLUL1	clusterin-like 1 (retinal)
chr12_+_18414446	0.21	ENST00000433979.1	PIK3C2G	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chrX_+_54947229	0.21	ENST00000442098.1 ENST00000430420.1 ENST00000453081.1 ENST00000173898.7 ENST00000319167.8 ENST00000375022.4 ENST00000399736.1 ENST00000440072.1 ENST00000420798.2 ENST00000431115.1 ENST00000440759.1 ENST00000375041.2	TRO	trophinin
chr4_-_74486217	0.20	ENST00000335049.5 ENST00000307439.5	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr7_-_82792215	0.20	ENST00000333891.9 ENST00000423517.2	PCLO	piccolo presynaptic cytomatrix protein
chr6_-_111927062	0.19	ENST00000359831.4	TRAF3IP2	TRAF3 interacting protein 2
chr17_+_46970134	0.19	ENST00000503641.1 ENST00000514808.1	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr15_-_72563585	0.19	ENST00000287196.9 ENST00000260376.7	PARP6	poly (ADP-ribose) polymerase family, member 6
chr11_+_77532155	0.19	ENST00000532481.1 ENST00000526415.1 ENST00000393427.2 ENST00000527134.1 ENST00000304716.8	AAMDC	adipogenesis associated, Mth938 domain containing
chr1_+_226013047	0.18	ENST00000366837.4	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr7_-_105029812	0.18	ENST00000482897.1	SRPK2	SRSF protein kinase 2
chr4_+_88754113	0.18	ENST00000560249.1 ENST00000540395.1 ENST00000511670.1 ENST00000361056.3	MEPE	matrix extracellular phosphoglycoprotein
chr7_-_99716952	0.18	ENST00000523306.1 ENST00000344095.4 ENST00000417349.1 ENST00000493322.1 ENST00000520135.1 ENST00000418432.2 ENST00000460673.2 ENST00000452041.1 ENST00000452438.2 ENST00000451699.1 ENST00000453269.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_-_48164812	0.18	ENST00000549151.1 ENST00000548919.1	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_86934526	0.17	ENST00000394711.1	CLCA1	chloride channel accessory 1
chr12_-_65146636	0.17	ENST00000418919.2	GNS	glucosamine (N-acetyl)-6-sulfatase
chr17_+_46970178	0.17	ENST00000393366.2 ENST00000506855.1	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_-_67266939	0.17	ENST00000304526.2	INSL5	insulin-like 5
chr11_-_117748138	0.17	ENST00000527717.1	FXYD6	FXYD domain containing ion transport regulator 6
chr1_+_151735431	0.17	ENST00000321531.5 ENST00000315067.8	OAZ3	ornithine decarboxylase antizyme 3
chr2_+_211421262	0.17	ENST00000233072.5	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr3_-_69129501	0.17	ENST00000540295.1 ENST00000415609.2 ENST00000361055.4 ENST00000349511.4	UBA3	ubiquitin-like modifier activating enzyme 3
chrX_+_38211777	0.16	ENST00000039007.4	OTC	ornithine carbamoyltransferase
chr17_+_46970127	0.16	ENST00000355938.5	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr12_-_10962767	0.16	ENST00000240691.2	TAS2R9	taste receptor, type 2, member 9
chr13_-_47471155	0.16	ENST00000543956.1 ENST00000542664.1	HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr18_-_13915530	0.16	ENST00000327606.3	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr1_+_117544366	0.16	ENST00000256652.4 ENST00000369470.1	CD101	CD101 molecule
chr7_-_83824169	0.15	ENST00000265362.4	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_107443652	0.15	ENST00000340010.5 ENST00000422236.2 ENST00000453332.1	SLC26A3	solute carrier family 26 (anion exchanger), member 3
chr7_-_81399329	0.15	ENST00000453411.1 ENST00000444829.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_-_37051798	0.15	ENST00000258829.5	NKX2-8	NK2 homeobox 8
chr5_+_148737562	0.15	ENST00000274569.4	PCYOX1L	prenylcysteine oxidase 1 like
chr8_+_105235572	0.15	ENST00000523362.1	RIMS2	regulating synaptic membrane exocytosis 2
chr5_+_140602904	0.15	ENST00000515856.2 ENST00000239449.4	PCDHB14	protocadherin beta 14
chr12_+_20963647	0.14	ENST00000381545.3	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr19_+_50016610	0.14	ENST00000596975.1	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr11_-_117747607	0.14	ENST00000540359.1 ENST00000539526.1	FXYD6	FXYD domain containing ion transport regulator 6
chr6_-_138539627	0.14	ENST00000527246.2	PBOV1	prostate and breast cancer overexpressed 1
chr1_-_149900122	0.14	ENST00000271628.8	SF3B4	splicing factor 3b, subunit 4, 49kDa
chr1_-_48866517	0.14	ENST00000371841.1	SPATA6	spermatogenesis associated 6
chr1_-_151762943	0.14	ENST00000368825.3 ENST00000368823.1 ENST00000458431.2 ENST00000368827.6 ENST00000368824.3	TDRKH	tudor and KH domain containing
chr1_-_10532531	0.14	ENST00000377036.2 ENST00000377038.3	DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide
chr4_-_74486347	0.14	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr7_+_43152191	0.13	ENST00000395891.2	HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr2_-_74619152	0.13	ENST00000440727.1 ENST00000409240.1	DCTN1	dynactin 1

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	2.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	5.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	1.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	3.1	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.2	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0005607	laminin-2 complex(GO:0005607)
0.4	1.2	GO:0005879	axonemal microtubule(GO:0005879)
0.2	3.6	GO:0097512	cardiac myofibril(GO:0097512)
0.2	0.7	GO:0097224	sperm connecting piece(GO:0097224)
0.2	2.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.7	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	5.9	GO:0002102	podosome(GO:0002102)
0.1	0.3	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	1.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.7	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.2	GO:1990075	periciliary membrane compartment(GO:1990075)
0.1	2.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.2	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	2.5	GO:0045095	keratin filament(GO:0045095)
0.1	0.4	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.1	0.5	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.2	GO:0032797	SMN complex(GO:0032797)
0.0	1.9	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.6	GO:0060077	inhibitory synapse(GO:0060077)
0.0	1.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	1.2	GO:0030673	axolemma(GO:0030673)
0.0	2.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.7	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	1.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0097452	GAIT complex(GO:0097452)
0.0	3.2	GO:0005604	basement membrane(GO:0005604)
0.0	2.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.5	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	1.0	GO:0005859	muscle myosin complex(GO:0005859)
0.0	1.0	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.1	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.4	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.7	GO:0031672	A band(GO:0031672)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	6.7	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	1.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)
0.0	0.8	GO:0005882	intermediate filament(GO:0005882)
0.0	0.2	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.5	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.2	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.7	2.2	GO:1990523	bone regeneration(GO:1990523)
0.7	2.1	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.3	1.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241)
0.3	1.4	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3	1.2	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.3	2.8	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3	6.3	GO:0003334	keratinocyte development(GO:0003334)
0.3	1.6	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.3	0.8	GO:0051795	positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2	1.6	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2	1.9	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	2.3	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.2	1.4	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2	2.5	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	0.6	GO:0019417	sulfur oxidation(GO:0019417)
0.2	1.2	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.2	3.6	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	1.9	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.2	1.2	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2	0.5	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2	1.3	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	0.5	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2	0.5	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.1	0.7	GO:0097338	response to clozapine(GO:0097338)
0.1	0.6	GO:0090107	aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1	0.4	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1	2.8	GO:0001765	membrane raft assembly(GO:0001765)
0.1	0.1	GO:1903625	negative regulation of DNA catabolic process(GO:1903625)
0.1	0.5	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1	0.6	GO:0035524	proline transmembrane transport(GO:0035524)
0.1	0.4	GO:0035425	autocrine signaling(GO:0035425)
0.1	0.7	GO:0006789	bilirubin conjugation(GO:0006789)
0.1	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1	0.9	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.8	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	1.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	2.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.5	GO:1901098	regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.1	0.2	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1	0.2	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.2	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.1	0.3	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.1	1.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	1.2	GO:0022038	corpus callosum development(GO:0022038)
0.1	5.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.7	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	1.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.6	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.1	0.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1	1.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	1.0	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.2	GO:0007113	endomitotic cell cycle(GO:0007113)
0.1	0.2	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1	0.3	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	0.4	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.2	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0	0.3	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.2	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.2	GO:0048880	sensory system development(GO:0048880)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.0	1.0	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.5	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.3	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.1	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.2	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0061110	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0	0.1	GO:0003218	cardiac left ventricle formation(GO:0003218)
0.0	0.2	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0	0.0	GO:0038093	Fc receptor signaling pathway(GO:0038093) Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	1.3	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.5	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0	0.8	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	1.5	GO:0030835	negative regulation of actin filament depolymerization(GO:0030835)
0.0	0.5	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.8	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.1	GO:0070543	response to linoleic acid(GO:0070543)
0.0	0.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	1.4	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	0.2	GO:0019532	oxalate transport(GO:0019532)
0.0	0.4	GO:0043010	camera-type eye development(GO:0043010)
0.0	0.4	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.0	1.8	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.5	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	0.6	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.0	0.3	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.1	GO:0051012	microtubule sliding(GO:0051012)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	2.8	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.5	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.5	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0018874	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0002881	microglial cell activation involved in immune response(GO:0002282) negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0	0.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	0.2	GO:0048490	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.3	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.7	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0060161	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	1.0	GO:0009301	snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.5	GO:0008347	glial cell migration(GO:0008347)
0.0	1.2	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.3	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.4	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.3	GO:0042981	regulation of apoptotic process(GO:0042981)
0.0	0.6	GO:0003009	skeletal muscle contraction(GO:0003009)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.1	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	1.9	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.0	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	3.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	1.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	2.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	5.2	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.3	1.9	GO:1990254	keratin filament binding(GO:1990254)
0.3	6.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.3	1.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	1.4	GO:0047086	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.2	1.6	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	0.6	GO:0090556	apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2	2.1	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	3.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.8	GO:0017018	myosin phosphatase activity(GO:0017018)
0.1	1.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.6	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	1.2	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	2.2	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	1.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.5	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	1.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	1.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.7	GO:0032027	myosin light chain binding(GO:0032027)
0.1	4.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1	1.8	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	1.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	7.0	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.7	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.2	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.7	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0	1.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	1.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	1.3	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	1.5	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.6	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.6	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	1.3	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.5	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.0	0.5	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.5	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.0	0.7	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	1.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	3.0	GO:0044325	ion channel binding(GO:0044325)
0.0	0.5	GO:0071949	FAD binding(GO:0071949)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0	1.2	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.3	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.2	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.0	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)