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ENCODE cell lines, expression (Ernst 2011)

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Results for EOMES

Z-value: 1.02

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Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
EOMES
ENSG00000163508.8 EOMES

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_28681950 1.65 ENST00000251081.6
 DSC2
 desmocollin 2
chr1_-_207095324 1.48 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
 FAIM3
 Fas apoptotic inhibitory molecule 3
chr1_-_207095212 1.39 ENST00000420007.2
 FAIM3
 Fas apoptotic inhibitory molecule 3
chr16_+_202686 1.37 ENST00000252951.2
 HBZ
 hemoglobin, zeta
chr1_-_184943610 1.22 ENST00000367511.3
 FAM129A
 family with sequence similarity 129, member A
chr3_+_50649302 1.06 ENST00000446044.1
 MAPKAPK3
 mitogen-activated protein kinase-activated protein kinase 3
chrX_+_131157290 1.05 ENST00000394334.2
 MST4
 Serine/threonine-protein kinase MST4
chrX_+_131157322 1.03 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
 MST4
 Serine/threonine-protein kinase MST4
chr19_-_51456321 0.91 ENST00000391809.2
 KLK5
 kallikrein-related peptidase 5
chr12_+_93965609 0.90 ENST00000549887.1
ENST00000551556.1
 SOCS2
 suppressor of cytokine signaling 2
chr19_-_51456344 0.89 ENST00000336334.3
ENST00000593428.1
 KLK5
 kallikrein-related peptidase 5
chr1_-_193029192 0.86 ENST00000417752.1
ENST00000367452.4
 UCHL5
 ubiquitin carboxyl-terminal hydrolase L5
chr11_-_107729887 0.84 ENST00000525815.1
 SLC35F2
 solute carrier family 35, member F2
chr17_-_39942940 0.81 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
 JUP
 junction plakoglobin
chr2_-_99224915 0.78 ENST00000328709.3
ENST00000409997.1
 COA5
 cytochrome c oxidase assembly factor 5
chr1_+_65775204 0.74 ENST00000371069.4
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_167452262 0.74 ENST00000487947.2
 PDCD10
 programmed cell death 10
chr3_-_50649192 0.74 ENST00000443053.2
ENST00000348721.3
 CISH
 cytokine inducible SH2-containing protein
chr1_-_149814478 0.74 ENST00000369161.3
 HIST2H2AA3
 histone cluster 2, H2aa3
chr15_+_89182178 0.72 ENST00000559876.1
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr14_-_67878917 0.71 ENST00000216446.4
 PLEK2
 pleckstrin 2
chr10_-_101190202 0.69 ENST00000543866.1
ENST00000370508.5
 GOT1
 glutamic-oxaloacetic transaminase 1, soluble
chr1_+_1981890 0.68 ENST00000378567.3
ENST00000468310.1
 PRKCZ
 protein kinase C, zeta
chr4_-_144940477 0.66 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
 GYPB
 glycophorin B (MNS blood group)
chr22_-_37545972 0.66 ENST00000216223.5
 IL2RB
 interleukin 2 receptor, beta
chr5_+_75699149 0.64 ENST00000379730.3
 IQGAP2
 IQ motif containing GTPase activating protein 2
chr2_-_170430277 0.64 ENST00000438035.1
ENST00000453929.2
 FASTKD1
 FAST kinase domains 1
chr1_+_150459873 0.64 ENST00000438568.2
ENST00000369054.2
ENST00000369064.3
ENST00000606933.1
 TARS2
 threonyl-tRNA synthetase 2, mitochondrial (putative)
chr7_-_87505658 0.62 ENST00000341119.5
 SLC25A40
 solute carrier family 25, member 40
chr2_-_235405168 0.61 ENST00000339728.3
 ARL4C
 ADP-ribosylation factor-like 4C
chr15_+_89182156 0.60 ENST00000379224.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr7_-_99698338 0.60 ENST00000354230.3
ENST00000425308.1
 MCM7
 minichromosome maintenance complex component 7
chr15_+_41136586 0.60 ENST00000431806.1
 SPINT1
 serine peptidase inhibitor, Kunitz type 1
chr2_-_163175133 0.59 ENST00000421365.2
ENST00000263642.2
 IFIH1
 interferon induced with helicase C domain 1
chr7_+_87505544 0.58 ENST00000265728.1
 DBF4
 DBF4 homolog (S. cerevisiae)
chr18_-_19284724 0.56 ENST00000580981.1
ENST00000289119.2
 ABHD3
 abhydrolase domain containing 3
chr8_+_144099914 0.55 ENST00000521699.1
ENST00000520531.1
ENST00000520466.1
ENST00000521003.1
ENST00000522528.1
ENST00000522971.1
ENST00000519611.1
ENST00000521182.1
ENST00000519546.1
ENST00000523847.1
ENST00000522024.1
 LY6E
 lymphocyte antigen 6 complex, locus E
chr1_+_70876891 0.54 ENST00000411986.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr1_+_70876926 0.49 ENST00000370938.3
ENST00000346806.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr15_+_89181974 0.49 ENST00000306072.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr8_+_144099896 0.49 ENST00000292494.6
ENST00000429120.2
 LY6E
 lymphocyte antigen 6 complex, locus E
chr7_+_55177416 0.46 ENST00000450046.1
ENST00000454757.2
 EGFR
 epidermal growth factor receptor
chr19_-_14629224 0.45 ENST00000254322.2
 DNAJB1
 DnaJ (Hsp40) homolog, subfamily B, member 1
chr13_+_28194873 0.43 ENST00000302979.3
 POLR1D
 polymerase (RNA) I polypeptide D, 16kDa
chr3_-_167452298 0.42 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
 PDCD10
 programmed cell death 10
chr2_-_148778258 0.42 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
 ORC4
 origin recognition complex, subunit 4
chr13_+_28195988 0.42 ENST00000399697.3
ENST00000399696.1
 POLR1D
 polymerase (RNA) I polypeptide D, 16kDa
chr8_+_86089619 0.42 ENST00000256117.5
ENST00000416274.2
 E2F5
 E2F transcription factor 5, p130-binding
chr1_-_205744205 0.42 ENST00000446390.2
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr20_-_18038521 0.41 ENST00000278780.6
 OVOL2
 ovo-like zinc finger 2
chr6_+_31583761 0.41 ENST00000376049.4
 AIF1
 allograft inflammatory factor 1
chr11_+_111896320 0.41 ENST00000531306.1
ENST00000537636.1
 DLAT
 dihydrolipoamide S-acetyltransferase
chr1_+_213031570 0.40 ENST00000366971.4
 FLVCR1
 feline leukemia virus subgroup C cellular receptor 1
chr4_-_151936865 0.39 ENST00000535741.1
 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
chr7_-_37024665 0.39 ENST00000396040.2
 ELMO1
 engulfment and cell motility 1
chr11_-_57103327 0.39 ENST00000529002.1
ENST00000278412.2
 SSRP1
 structure specific recognition protein 1
chr22_-_18257178 0.39 ENST00000342111.5
 BID
 BH3 interacting domain death agonist
chr16_+_30064444 0.38 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
 ALDOA
 aldolase A, fructose-bisphosphate
chr1_-_25747283 0.38 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
 RHCE
 Rh blood group, CcEe antigens
chr1_+_25598989 0.38 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chr12_+_6554021 0.38 ENST00000266557.3
 CD27
 CD27 molecule
chr16_-_67693846 0.37 ENST00000602850.1
 ACD
 adrenocortical dysplasia homolog (mouse)
chr1_+_19578033 0.37 ENST00000330263.4
 MRTO4
 mRNA turnover 4 homolog (S. cerevisiae)
chr6_-_111927062 0.37 ENST00000359831.4
 TRAF3IP2
 TRAF3 interacting protein 2
chr3_+_141121164 0.37 ENST00000510338.1
ENST00000504673.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr2_-_148778323 0.37 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
 ORC4
 origin recognition complex, subunit 4
chr8_-_8318847 0.36 ENST00000521218.1
 CTA-398F10.2
 CTA-398F10.2
chr17_-_18585131 0.36 ENST00000443457.1
ENST00000583002.1
 ZNF286B
 zinc finger protein 286B
chr9_+_136223414 0.36 ENST00000371964.4
 SURF2
 surfeit 2
chrX_-_63005405 0.36 ENST00000374878.1
ENST00000437457.2
 ARHGEF9
 Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_+_34204642 0.36 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1
 high mobility group AT-hook 1
chr6_-_35888824 0.35 ENST00000361690.3
ENST00000512445.1
 SRPK1
 SRSF protein kinase 1
chr11_+_63706444 0.35 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
 NAA40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr18_+_43753974 0.35 ENST00000282059.6
ENST00000321319.6
 C18orf25
 chromosome 18 open reading frame 25
chr2_-_31637560 0.34 ENST00000379416.3
 XDH
 xanthine dehydrogenase
chr1_-_167906277 0.34 ENST00000271373.4
 MPC2
 mitochondrial pyruvate carrier 2
chr19_+_33865218 0.34 ENST00000585933.2
 CEBPG
 CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_93426998 0.34 ENST00000370310.4
 FAM69A
 family with sequence similarity 69, member A
chr2_+_61108771 0.34 ENST00000394479.3
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr10_+_5454505 0.34 ENST00000355029.4
 NET1
 neuroepithelial cell transforming 1
chr2_+_61108650 0.33 ENST00000295025.8
 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
chr8_+_126010783 0.33 ENST00000521232.1
 SQLE
 squalene epoxidase
chr1_-_205744574 0.33 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
 RAB7L1
 RAB7, member RAS oncogene family-like 1
chr19_-_39108568 0.33 ENST00000586296.1
 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
chr3_-_182698381 0.33 ENST00000292782.4
 DCUN1D1
 DCN1, defective in cullin neddylation 1, domain containing 1
chr17_-_62493131 0.33 ENST00000539111.2
 POLG2
 polymerase (DNA directed), gamma 2, accessory subunit
chr22_+_47070490 0.33 ENST00000408031.1
 GRAMD4
 GRAM domain containing 4
chr1_-_245027833 0.33 ENST00000444376.2
 HNRNPU
 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr17_+_79989937 0.33 ENST00000580965.1
 RAC3
 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr19_+_49838653 0.33 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
 CD37
 CD37 molecule
chr3_+_111805182 0.32 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
 C3orf52
 chromosome 3 open reading frame 52
chr9_+_37486005 0.32 ENST00000377792.3
 POLR1E
 polymerase (RNA) I polypeptide E, 53kDa
chr11_+_111896090 0.32 ENST00000393051.1
 DLAT
 dihydrolipoamide S-acetyltransferase
chr15_-_43622736 0.32 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
 LCMT2
 leucine carboxyl methyltransferase 2
chr10_-_61900762 0.31 ENST00000355288.2
 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
chr17_+_46018872 0.31 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
 PNPO
 pyridoxamine 5'-phosphate oxidase
chr11_+_73498898 0.31 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
 MRPL48
 mitochondrial ribosomal protein L48
chr16_-_17564738 0.31 ENST00000261381.6
 XYLT1
 xylosyltransferase I
chr17_+_73521763 0.31 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
chr19_+_35645618 0.31 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
 FXYD5
 FXYD domain containing ion transport regulator 5
chr17_+_9066252 0.31 ENST00000436734.1
 NTN1
 netrin 1
chr1_-_213031418 0.30 ENST00000356684.3
ENST00000426161.1
ENST00000424044.1
 FLVCR1-AS1
 FLVCR1 antisense RNA 1 (head to head)
chr1_+_233086326 0.30 ENST00000366628.5
ENST00000366627.4
 NTPCR
 nucleoside-triphosphatase, cancer-related
chr11_+_64808675 0.30 ENST00000529996.1
 SAC3D1
 SAC3 domain containing 1
chrX_-_16730688 0.30 ENST00000359276.4
 CTPS2
 CTP synthase 2
chr9_+_37485932 0.30 ENST00000377798.4
ENST00000442009.2
 POLR1E
 polymerase (RNA) I polypeptide E, 53kDa
chr8_+_86089460 0.30 ENST00000418930.2
 E2F5
 E2F transcription factor 5, p130-binding
chr20_-_39317868 0.29 ENST00000373313.2
 MAFB
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr14_-_106963409 0.29 ENST00000390621.2
 IGHV1-45
 immunoglobulin heavy variable 1-45
chr1_+_25598872 0.29 ENST00000328664.4
 RHD
 Rh blood group, D antigen
chr22_-_30662828 0.29 ENST00000403463.1
ENST00000215781.2
 OSM
 oncostatin M
chr22_-_22221658 0.29 ENST00000544786.1
 MAPK1
 mitogen-activated protein kinase 1
chr8_-_9760839 0.29 ENST00000519461.1
ENST00000517675.1
 LINC00599
 long intergenic non-protein coding RNA 599
chr14_-_53162361 0.29 ENST00000395686.3
 ERO1L
 ERO1-like (S. cerevisiae)
chr7_+_28452130 0.29 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chr19_+_49496705 0.28 ENST00000595090.1
 RUVBL2
 RuvB-like AAA ATPase 2
chr9_-_117853297 0.28 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
 TNC
 tenascin C
chr11_+_63655987 0.28 ENST00000509502.2
ENST00000512060.1
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr3_+_44379944 0.27 ENST00000396078.3
ENST00000342649.4
 TCAIM
 T cell activation inhibitor, mitochondrial
chr20_-_57617831 0.27 ENST00000371033.5
ENST00000355937.4
 SLMO2
 slowmo homolog 2 (Drosophila)
chr5_-_112630598 0.27 ENST00000302475.4
 MCC
 mutated in colorectal cancers
chr17_-_27405875 0.27 ENST00000359450.6
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chr1_+_37940153 0.27 ENST00000373087.6
 ZC3H12A
 zinc finger CCCH-type containing 12A
chr12_-_99288536 0.27 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
 ANKS1B
 ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_94333784 0.27 ENST00000265986.6
 IDE
 insulin-degrading enzyme
chr1_+_162531294 0.27 ENST00000367926.4
ENST00000271469.3
 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
chr15_+_48623600 0.27 ENST00000558813.1
ENST00000331200.3
ENST00000558472.1
 DUT
 deoxyuridine triphosphatase
chr19_-_39108552 0.27 ENST00000591517.1
 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
chr19_+_34856141 0.27 ENST00000586425.1
 GPI
 glucose-6-phosphate isomerase
chr19_+_35645817 0.27 ENST00000423817.3
 FXYD5
 FXYD domain containing ion transport regulator 5
chr4_-_26492076 0.26 ENST00000295589.3
 CCKAR
 cholecystokinin A receptor
chr1_+_150229554 0.26 ENST00000369111.4
 CA14
 carbonic anhydrase XIV
chr11_+_117947724 0.26 ENST00000534111.1
 TMPRSS4
 transmembrane protease, serine 4
chr4_+_17812525 0.26 ENST00000251496.2
 NCAPG
 non-SMC condensin I complex, subunit G
chr1_-_167906020 0.26 ENST00000458574.1
 MPC2
 mitochondrial pyruvate carrier 2
chr16_+_30064411 0.26 ENST00000338110.5
 ALDOA
 aldolase A, fructose-bisphosphate
chr22_-_22221900 0.26 ENST00000215832.6
ENST00000398822.3
 MAPK1
 mitogen-activated protein kinase 1
chr1_-_245027766 0.26 ENST00000283179.9
 HNRNPU
 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr16_-_67694129 0.25 ENST00000602320.1
 ACD
 adrenocortical dysplasia homolog (mouse)
chr11_+_64808368 0.25 ENST00000531072.1
ENST00000398846.1
 SAC3D1
 SAC3 domain containing 1
chr17_-_17740287 0.25 ENST00000355815.4
ENST00000261646.5
 SREBF1
 sterol regulatory element binding transcription factor 1
chr5_+_96271141 0.25 ENST00000231368.5
 LNPEP
 leucyl/cystinyl aminopeptidase
chr8_+_73449625 0.25 ENST00000523207.1
 KCNB2
 potassium voltage-gated channel, Shab-related subfamily, member 2
chr2_+_45878790 0.24 ENST00000306156.3
 PRKCE
 protein kinase C, epsilon
chr9_+_139780942 0.24 ENST00000247668.2
ENST00000359662.3
 TRAF2
 TNF receptor-associated factor 2
chr3_-_167452614 0.24 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
 PDCD10
 programmed cell death 10
chr5_-_33892204 0.24 ENST00000504830.1
 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr16_-_87367879 0.24 ENST00000568879.1
 RP11-178L8.4
 RP11-178L8.4
chr12_-_33049690 0.24 ENST00000070846.6
ENST00000340811.4
 PKP2
 plakophilin 2
chr1_-_246729544 0.24 ENST00000544618.1
ENST00000366514.4
 TFB2M
 transcription factor B2, mitochondrial
chr10_+_75910960 0.24 ENST00000539909.1
ENST00000286621.2
 ADK
 adenosine kinase
chr18_+_2655692 0.24 ENST00000320876.6
 SMCHD1
 structural maintenance of chromosomes flexible hinge domain containing 1
chr1_+_160051319 0.24 ENST00000368088.3
 KCNJ9
 potassium inwardly-rectifying channel, subfamily J, member 9
chr11_+_117947782 0.23 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
 TMPRSS4
 transmembrane protease, serine 4
chr3_+_132379154 0.23 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
 UBA5
 ubiquitin-like modifier activating enzyme 5
chr20_+_48807351 0.23 ENST00000303004.3
 CEBPB
 CCAAT/enhancer binding protein (C/EBP), beta
chr16_+_29817841 0.23 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
 MAZ
 MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_-_75498308 0.23 ENST00000569540.1
 TMEM170A
 transmembrane protein 170A
chr11_+_65479702 0.23 ENST00000530446.1
ENST00000534104.1
ENST00000530605.1
ENST00000528198.1
ENST00000531880.1
ENST00000534650.1
 KAT5
 K(lysine) acetyltransferase 5
chr14_+_32546274 0.23 ENST00000396582.2
 ARHGAP5
 Rho GTPase activating protein 5
chr4_+_128554081 0.23 ENST00000335251.6
ENST00000296461.5
 INTU
 inturned planar cell polarity protein
chr15_-_70388943 0.23 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr12_-_63328817 0.23 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_-_58120996 0.23 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
 ZWINT
 ZW10 interacting kinetochore protein
chr19_+_49496782 0.23 ENST00000601968.1
ENST00000596837.1
 RUVBL2
 RuvB-like AAA ATPase 2
chr12_+_94071341 0.23 ENST00000542893.2
 CRADD
 CASP2 and RIPK1 domain containing adaptor with death domain
chr3_-_127842612 0.22 ENST00000417360.1
ENST00000322623.5
 RUVBL1
 RuvB-like AAA ATPase 1
chr7_+_16793160 0.22 ENST00000262067.4
 TSPAN13
 tetraspanin 13
chr11_-_62439012 0.22 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
 C11orf48
 chromosome 11 open reading frame 48
chr15_+_48623208 0.22 ENST00000559935.1
ENST00000559416.1
 DUT
 deoxyuridine triphosphatase
chr21_-_46962379 0.22 ENST00000311124.4
ENST00000380010.4
 SLC19A1
 solute carrier family 19 (folate transporter), member 1
chr13_+_73302047 0.22 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
 BORA
 bora, aurora kinase A activator
chrX_+_150151824 0.22 ENST00000455596.1
ENST00000448905.2
 HMGB3
 high mobility group box 3
chr5_+_96211643 0.22 ENST00000437043.3
ENST00000510373.1
 ERAP2
 endoplasmic reticulum aminopeptidase 2
chr15_-_90777277 0.22 ENST00000328649.6
 CIB1
 calcium and integrin binding 1 (calmyrin)
chr3_+_196466710 0.22 ENST00000327134.3
 PAK2
 p21 protein (Cdc42/Rac)-activated kinase 2
chr7_+_100026406 0.21 ENST00000414441.1
 MEPCE
 methylphosphate capping enzyme
chr17_+_4736627 0.21 ENST00000355280.6
ENST00000347992.7
 MINK1
 misshapen-like kinase 1
chr3_-_167452703 0.21 ENST00000497056.2
ENST00000473645.2
 PDCD10
 programmed cell death 10
chr1_-_21113105 0.21 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
 HP1BP3
 heterochromatin protein 1, binding protein 3
chr19_-_39108643 0.21 ENST00000396857.2
 MAP4K1
 mitogen-activated protein kinase kinase kinase kinase 1
chr8_-_79717750 0.21 ENST00000263851.4
ENST00000379113.2
 IL7
 interleukin 7
chr2_-_40006289 0.21 ENST00000260619.6
ENST00000454352.2
 THUMPD2
 THUMP domain containing 2
chr1_+_209757051 0.21 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
 CAMK1G
 calcium/calmodulin-dependent protein kinase IG
chr19_+_19303008 0.21 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
 RFXANK
 regulatory factor X-associated ankyrin-containing protein
chr1_+_222791417 0.21 ENST00000344922.5
ENST00000344441.6
ENST00000344507.1
 MIA3
 melanoma inhibitory activity family, member 3
chr1_+_215256467 0.20 ENST00000391894.2
ENST00000444842.2
 KCNK2
 potassium channel, subfamily K, member 2
chr6_+_41888926 0.20 ENST00000230340.4
 BYSL
 bystin-like
chr7_+_29234028 0.20 ENST00000222792.6
 CHN2
 chimerin 2
chr16_-_75498553 0.20 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
 TMEM170A
RP11-77K12.1
 transmembrane protein 170A
Uncharacterized protein
chr15_+_44580899 0.20 ENST00000559222.1
ENST00000299957.6
 CASC4
 cancer susceptibility candidate 4
chr18_-_47017956 0.20 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
 RPL17-C18orf32
RPL17
 RPL17-C18orf32 readthrough
ribosomal protein L17
chr22_-_46373004 0.20 ENST00000339464.4
 WNT7B
 wingless-type MMTV integration site family, member 7B
chr10_+_85899196 0.19 ENST00000372134.3
 GHITM
 growth hormone inducible transmembrane protein
chrX_-_71933888 0.19 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
 PHKA1
 phosphorylase kinase, alpha 1 (muscle)
chr3_+_44379611 0.19 ENST00000383746.3
ENST00000417237.1
 TCAIM
 T cell activation inhibitor, mitochondrial
chr7_-_93520191 0.19 ENST00000545378.1
 TFPI2
 tissue factor pathway inhibitor 2
chr5_+_52083730 0.19 ENST00000282588.6
ENST00000274311.2
 ITGA1
PELO
 integrin, alpha 1
pelota homolog (Drosophila)
chr19_+_50084561 0.19 ENST00000246794.5
 PRRG2
 proline rich Gla (G-carboxyglutamic acid) 2
chrX_+_21958674 0.19 ENST00000404933.2
 SMS
 spermine synthase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 1.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.3 1.8 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.3 2.7 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3 1.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.7 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.2 0.6 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 0.6 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) positive regulation of telomeric DNA binding(GO:1904744)
0.2 0.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.5 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.2 0.6 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 0.5 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.6 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.6 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.1 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.5 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.3 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.7 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.3 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.4 GO:0060214 endocardium formation(GO:0060214)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.2 GO:0044209 AMP salvage(GO:0044209)
0.1 0.3 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.2 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.2 GO:0051958 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.1 GO:0043132 NAD transport(GO:0043132)
0.1 0.9 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.2 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:1902202 regulation of endothelial tube morphogenesis(GO:1901509) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.0 GO:0035549 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 1.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095) negative regulation of icosanoid secretion(GO:0032304)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0015866 adenine transport(GO:0015853) ADP transport(GO:0015866) negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0072757 cellular response to camptothecin(GO:0072757) response to camptothecin(GO:1901563)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0032898 nerve growth factor processing(GO:0032455) neurotrophin production(GO:0032898)
0.0 0.0 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.0 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.6 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.5 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.8 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 1.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 1.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.2 GO:0044305 calyx of Held(GO:0044305)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.1 0.2 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 1.9 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 2.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.9 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 2.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 0.6 GO:0004672 protein kinase activity(GO:0004672)
0.3 2.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 0.7 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 0.7 GO:0070546 phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.6 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 0.7 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 0.5 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 1.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 1.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.2 GO:0035276 ethanol binding(GO:0035276)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.0 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 1.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.0 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 1.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling