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ENCODE cell lines, expression (Ernst 2011)

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Results for EPAS1_BCL3

Z-value: 1.47

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Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
EPAS1
ENSG00000116016.9 EPAS1
BCL3
ENSG00000069399.8 BCL3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EPAS1hg19_v2_chr2_+_46524537_465245530.852.8e-05Click!
BCL3hg19_v2_chr19_+_45251804_452518400.448.5e-02Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_7080227 6.00 ENST00000574330.1
 ASGR1
 asialoglycoprotein receptor 1
chr3_-_32022733 4.44 ENST00000438237.2
ENST00000396556.2
 OSBPL10
 oxysterol binding protein-like 10
chr5_+_52776228 4.43 ENST00000256759.3
 FST
 follistatin
chr1_+_86046433 4.10 ENST00000451137.2
 CYR61
 cysteine-rich, angiogenic inducer, 61
chr11_+_19798964 4.09 ENST00000527559.2
 NAV2
 neuron navigator 2
chr19_+_35629702 3.72 ENST00000351325.4
 FXYD1
 FXYD domain containing ion transport regulator 1
chr7_-_107642348 3.69 ENST00000393561.1
 LAMB1
 laminin, beta 1
chr2_+_20646824 3.62 ENST00000272233.4
 RHOB
 ras homolog family member B
chr22_-_29075853 3.56 ENST00000397906.2
 TTC28
 tetratricopeptide repeat domain 28
chr16_+_1578674 3.00 ENST00000253934.5
 TMEM204
 transmembrane protein 204
chr11_+_19799327 2.82 ENST00000540292.1
 NAV2
 neuron navigator 2
chr12_+_66217911 2.80 ENST00000403681.2
 HMGA2
 high mobility group AT-hook 2
chr10_-_62761188 2.77 ENST00000357917.4
 RHOBTB1
 Rho-related BTB domain containing 1
chr16_+_82068830 2.69 ENST00000199936.4
 HSD17B2
 hydroxysteroid (17-beta) dehydrogenase 2
chr5_+_52776449 2.68 ENST00000396947.3
 FST
 follistatin
chr9_+_103790991 2.57 ENST00000374874.3
 LPPR1
 Lipid phosphate phosphatase-related protein type 1
chr17_-_7017559 2.53 ENST00000446679.2
 ASGR2
 asialoglycoprotein receptor 2
chr2_-_238499303 2.38 ENST00000409576.1
 RAB17
 RAB17, member RAS oncogene family
chr5_+_52285144 2.38 ENST00000296585.5
 ITGA2
 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr16_+_72090053 2.36 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
 HP
 haptoglobin
chr20_+_34680620 2.28 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
chr8_-_134309335 2.21 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
 NDRG1
 N-myc downstream regulated 1
chr3_-_99833333 2.17 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
 FILIP1L
 filamin A interacting protein 1-like
chr6_+_31620191 2.17 ENST00000375918.2
ENST00000375920.4
 APOM
 apolipoprotein M
chr16_-_70719925 2.12 ENST00000338779.6
 MTSS1L
 metastasis suppressor 1-like
chr3_-_134093275 2.08 ENST00000513145.1
ENST00000422605.2
 AMOTL2
 angiomotin like 2
chr7_+_100770328 2.04 ENST00000223095.4
ENST00000445463.2
 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr20_-_50385138 2.02 ENST00000338821.5
 ATP9A
 ATPase, class II, type 9A
chr22_-_36236265 1.98 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_27462822 1.97 ENST00000522098.1
 CLU
 clusterin
chr7_-_29234802 1.95 ENST00000449801.1
ENST00000409850.1
 CPVL
 carboxypeptidase, vitellogenic-like
chr12_-_7261772 1.93 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
 C1RL
 complement component 1, r subcomponent-like
chr3_-_52479043 1.92 ENST00000231721.2
ENST00000475739.1
 SEMA3G
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr4_+_74275057 1.88 ENST00000511370.1
 ALB
 albumin
chr19_+_45449301 1.86 ENST00000591597.1
 APOC2
 apolipoprotein C-II
chr17_-_41623075 1.85 ENST00000545089.1
 ETV4
 ets variant 4
chr8_-_18541603 1.82 ENST00000428502.2
 PSD3
 pleckstrin and Sec7 domain containing 3
chr19_+_45449266 1.69 ENST00000592257.1
 APOC2
 apolipoprotein C-II
chr4_+_38869410 1.69 ENST00000358869.2
 FAM114A1
 family with sequence similarity 114, member A1
chr1_-_161193349 1.62 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
 APOA2
 apolipoprotein A-II
chr22_-_36236623 1.60 ENST00000405409.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_+_35776828 1.58 ENST00000216117.8
 HMOX1
 heme oxygenase (decycling) 1
chr10_+_123923105 1.55 ENST00000368999.1
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr3_+_30647994 1.54 ENST00000295754.5
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr14_-_54420133 1.53 ENST00000559501.1
ENST00000558984.1
 BMP4
 bone morphogenetic protein 4
chr19_+_45449228 1.51 ENST00000252490.4
 APOC2
 apolipoprotein C-II
chr2_-_56150910 1.50 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr4_-_186732048 1.50 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
 SORBS2
 sorbin and SH3 domain containing 2
chr5_-_39425068 1.48 ENST00000515700.1
ENST00000339788.6
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_41623009 1.41 ENST00000393664.2
 ETV4
 ets variant 4
chr17_-_41623691 1.35 ENST00000545954.1
 ETV4
 ets variant 4
chr10_+_123923205 1.35 ENST00000369004.3
ENST00000260733.3
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr6_-_31620455 1.35 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
 BAG6
 BCL2-associated athanogene 6
chr6_-_31620403 1.30 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
 BAG6
 BCL2-associated athanogene 6
chr20_-_36793774 1.27 ENST00000361475.2
 TGM2
 transglutaminase 2
chr2_-_56150184 1.26 ENST00000394554.1
 EFEMP1
 EGF containing fibulin-like extracellular matrix protein 1
chr17_+_2699697 1.25 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chrX_-_99891796 1.23 ENST00000373020.4
 TSPAN6
 tetraspanin 6
chr3_+_30648066 1.23 ENST00000359013.4
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr5_-_42825983 1.21 ENST00000506577.1
 SEPP1
 selenoprotein P, plasma, 1
chr2_-_238499337 1.20 ENST00000411462.1
ENST00000409822.1
 RAB17
 RAB17, member RAS oncogene family
chr2_-_220436248 1.16 ENST00000265318.4
 OBSL1
 obscurin-like 1
chr17_-_41623259 1.15 ENST00000538265.1
ENST00000591713.1
 ETV4
 ets variant 4
chr1_-_21671968 1.15 ENST00000415912.2
 ECE1
 endothelin converting enzyme 1
chr11_-_70507901 1.14 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr19_+_45445491 1.13 ENST00000592954.1
ENST00000419266.2
ENST00000589057.1
 APOC4
APOC4-APOC2
 apolipoprotein C-IV
APOC4-APOC2 readthrough (NMD candidate)
chr17_-_41623716 1.08 ENST00000319349.5
 ETV4
 ets variant 4
chr6_-_31620149 1.07 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
 BAG6
 BCL2-associated athanogene 6
chr11_-_2170786 1.06 ENST00000300632.5
 IGF2
 insulin-like growth factor 2 (somatomedin A)
chr7_+_29519486 1.06 ENST00000409041.4
 CHN2
 chimerin 2
chrX_+_102631248 1.06 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr19_+_35630022 1.06 ENST00000589209.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr17_+_72427477 1.06 ENST00000342648.5
ENST00000481232.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr22_-_36424458 1.04 ENST00000438146.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_203595903 1.03 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
chr17_+_1665253 1.02 ENST00000254722.4
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_111967345 1.01 ENST00000332674.5
ENST00000453116.1
 MXI1
 MAX interactor 1, dimerization protein
chr2_-_238499131 1.00 ENST00000538644.1
 RAB17
 RAB17, member RAS oncogene family
chr3_-_134093395 1.00 ENST00000249883.5
 AMOTL2
 angiomotin like 2
chr8_+_21915368 1.00 ENST00000265800.5
ENST00000517418.1
 DMTN
 dematin actin binding protein
chr7_-_95064264 0.99 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
 PON2
 paraoxonase 2
chr8_+_123793633 0.97 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr18_+_3449821 0.96 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
 TGIF1
 TGFB-induced factor homeobox 1
chrX_+_105937068 0.96 ENST00000324342.3
 RNF128
 ring finger protein 128, E3 ubiquitin protein ligase
chr19_+_35630628 0.95 ENST00000588715.1
ENST00000588607.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chr2_-_188312971 0.94 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
 CALCRL
 calcitonin receptor-like
chr19_-_43382142 0.94 ENST00000597058.1
 PSG1
 pregnancy specific beta-1-glycoprotein 1
chr18_+_3449695 0.93 ENST00000343820.5
 TGIF1
 TGFB-induced factor homeobox 1
chr14_-_92413353 0.93 ENST00000556154.1
 FBLN5
 fibulin 5
chr5_-_96143796 0.92 ENST00000296754.3
 ERAP1
 endoplasmic reticulum aminopeptidase 1
chr14_+_101193246 0.91 ENST00000331224.6
 DLK1
 delta-like 1 homolog (Drosophila)
chr2_-_220435963 0.91 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
 OBSL1
 obscurin-like 1
chr17_+_1665345 0.91 ENST00000576406.1
ENST00000571149.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_+_34652164 0.89 ENST00000441545.2
ENST00000553620.1
 IL11RA
 interleukin 11 receptor, alpha
chr14_+_101193164 0.88 ENST00000341267.4
 DLK1
 delta-like 1 homolog (Drosophila)
chr3_-_149688502 0.86 ENST00000481767.1
ENST00000475518.1
 PFN2
 profilin 2
chr12_+_56473628 0.86 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
 ERBB3
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr16_+_16326352 0.86 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
 NOMO3
 NODAL modulator 3
chr19_-_36297348 0.84 ENST00000589835.1
 PRODH2
 proline dehydrogenase (oxidase) 2
chr19_+_41725088 0.84 ENST00000301178.4
 AXL
 AXL receptor tyrosine kinase
chr11_-_89224508 0.83 ENST00000525196.1
 NOX4
 NADPH oxidase 4
chr2_+_201170770 0.83 ENST00000409988.3
ENST00000409385.1
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr1_-_240775447 0.83 ENST00000318160.4
 GREM2
 gremlin 2, DAN family BMP antagonist
chr16_+_14927538 0.83 ENST00000287667.7
 NOMO1
 NODAL modulator 1
chr10_+_123922941 0.83 ENST00000360561.3
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr5_-_16916624 0.82 ENST00000513882.1
 MYO10
 myosin X
chr4_-_102268484 0.81 ENST00000394853.4
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_123970052 0.81 ENST00000373823.3
 GSN
 gelsolin
chr11_-_72433346 0.80 ENST00000334211.8
 ARAP1
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr16_-_18573396 0.80 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
 NOMO2
 NODAL modulator 2
chr3_+_37903432 0.77 ENST00000443503.2
 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr1_+_203595689 0.76 ENST00000357681.5
 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
chr18_+_29171689 0.76 ENST00000237014.3
 TTR
 transthyretin
chr2_+_102686820 0.75 ENST00000409929.1
ENST00000424272.1
 IL1R1
 interleukin 1 receptor, type I
chr15_+_96875657 0.75 ENST00000559679.1
ENST00000394171.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr19_+_54024251 0.75 ENST00000253144.9
 ZNF331
 zinc finger protein 331
chr5_-_172756506 0.75 ENST00000265087.4
 STC2
 stanniocalcin 2
chr3_+_179370517 0.74 ENST00000263966.3
 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
chrX_-_108976521 0.74 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
 ACSL4
 acyl-CoA synthetase long-chain family member 4
chr16_+_68279207 0.74 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
 PLA2G15
 phospholipase A2, group XV
chr8_+_21916710 0.73 ENST00000523266.1
ENST00000519907.1
 DMTN
 dematin actin binding protein
chr11_-_89224638 0.73 ENST00000535633.1
ENST00000263317.4
 NOX4
 NADPH oxidase 4
chr16_+_57662419 0.72 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
 GPR56
 G protein-coupled receptor 56
chr3_-_50340996 0.72 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
 HYAL1
 hyaluronoglucosaminidase 1
chr5_+_78365577 0.72 ENST00000518666.1
ENST00000521567.1
 BHMT2
 betaine--homocysteine S-methyltransferase 2
chr2_+_85360499 0.71 ENST00000282111.3
 TCF7L1
 transcription factor 7-like 1 (T-cell specific, HMG-box)
chr12_+_56473939 0.71 ENST00000450146.2
 ERBB3
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr5_+_78365536 0.70 ENST00000255192.3
 BHMT2
 betaine--homocysteine S-methyltransferase 2
chr16_+_31483451 0.70 ENST00000565360.1
ENST00000361773.3
 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
chr8_+_21916680 0.70 ENST00000358242.3
ENST00000415253.1
 DMTN
 dematin actin binding protein
chr11_-_27722021 0.70 ENST00000356660.4
ENST00000418212.1
ENST00000533246.1
 BDNF
 brain-derived neurotrophic factor
chr3_-_49459865 0.69 ENST00000427987.1
 AMT
 aminomethyltransferase
chr5_-_55290773 0.69 ENST00000502326.3
ENST00000381298.2
 IL6ST
 interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr11_+_66278080 0.69 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
 BBS1
 Bardet-Biedl syndrome 1
chr7_-_30029574 0.68 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
 SCRN1
 secernin 1
chr4_-_89152474 0.68 ENST00000515655.1
 ABCG2
 ATP-binding cassette, sub-family G (WHITE), member 2
chr19_-_52227221 0.68 ENST00000222115.1
ENST00000540069.2
 HAS1
 hyaluronan synthase 1
chr2_+_62900986 0.67 ENST00000405015.3
ENST00000413434.1
ENST00000426940.1
ENST00000449820.1
 EHBP1
 EH domain binding protein 1
chr19_+_35532612 0.67 ENST00000600390.1
ENST00000597419.1
 HPN
 hepsin
chr4_+_140586922 0.64 ENST00000265498.1
ENST00000506797.1
 MGST2
 microsomal glutathione S-transferase 2
chr12_+_133758115 0.64 ENST00000541009.2
ENST00000592241.1
 ZNF268
 zinc finger protein 268
chr15_-_60690932 0.63 ENST00000559818.1
 ANXA2
 annexin A2
chrX_+_135229600 0.63 ENST00000370690.3
 FHL1
 four and a half LIM domains 1
chr1_+_157963063 0.62 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
 KIRREL
 kin of IRRE like (Drosophila)
chrX_+_107069063 0.61 ENST00000262843.6
 MID2
 midline 2
chr3_+_52009110 0.61 ENST00000491470.1
 ABHD14A
 abhydrolase domain containing 14A
chr11_-_89224488 0.61 ENST00000534731.1
ENST00000527626.1
 NOX4
 NADPH oxidase 4
chr3_-_49459878 0.60 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
 AMT
 aminomethyltransferase
chr3_-_114035026 0.60 ENST00000570269.1
 RP11-553L6.5
 RP11-553L6.5
chr10_-_62704005 0.59 ENST00000337910.5
 RHOBTB1
 Rho-related BTB domain containing 1
chr2_+_201171064 0.59 ENST00000451764.2
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr4_-_102268628 0.59 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_21978312 0.59 ENST00000359708.4
ENST00000290101.4
 RAP1GAP
 RAP1 GTPase activating protein
chr1_+_17866290 0.58 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_+_29519662 0.58 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
 CHN2
 chimerin 2
chr2_-_27341765 0.58 ENST00000405600.1
 CGREF1
 cell growth regulator with EF-hand domain 1
chr5_-_146889619 0.57 ENST00000343218.5
 DPYSL3
 dihydropyrimidinase-like 3
chr2_+_201171372 0.57 ENST00000409140.3
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr19_+_11466062 0.56 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2
chr19_+_45973120 0.56 ENST00000592811.1
ENST00000586615.1
 FOSB
 FBJ murine osteosarcoma viral oncogene homolog B
chr20_+_30946106 0.56 ENST00000375687.4
ENST00000542461.1
 ASXL1
 additional sex combs like 1 (Drosophila)
chr19_+_11466167 0.56 ENST00000591608.1
 DKFZP761J1410
 Lipid phosphate phosphatase-related protein type 2
chr19_+_35630344 0.55 ENST00000455515.2
 FXYD1
 FXYD domain containing ion transport regulator 1
chr19_+_33685490 0.54 ENST00000253193.7
 LRP3
 low density lipoprotein receptor-related protein 3
chr10_+_115438920 0.54 ENST00000429617.1
ENST00000369331.4
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr22_+_24407642 0.53 ENST00000454754.1
ENST00000263119.5
 CABIN1
 calcineurin binding protein 1
chr3_-_114866084 0.53 ENST00000357258.3
 ZBTB20
 zinc finger and BTB domain containing 20
chr4_+_146402925 0.53 ENST00000302085.4
 SMAD1
 SMAD family member 1
chr2_-_220083671 0.53 ENST00000439002.2
 ABCB6
 ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_-_43709703 0.53 ENST00000599391.1
ENST00000244295.9
 PSG4
 pregnancy specific beta-1-glycoprotein 4
chr1_+_82266053 0.52 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2
 latrophilin 2
chr22_+_38142235 0.52 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
 TRIOBP
 TRIO and F-actin binding protein
chrX_+_135229559 0.52 ENST00000394155.2
 FHL1
 four and a half LIM domains 1
chr11_+_114128522 0.52 ENST00000535401.1
 NNMT
 nicotinamide N-methyltransferase
chr21_-_43786634 0.52 ENST00000291527.2
 TFF1
 trefoil factor 1
chr17_+_70117153 0.51 ENST00000245479.2
 SOX9
 SRY (sex determining region Y)-box 9
chr14_+_93260569 0.51 ENST00000163416.2
 GOLGA5
 golgin A5
chr1_+_214161272 0.51 ENST00000498508.2
ENST00000366958.4
 PROX1
 prospero homeobox 1
chr2_-_220083692 0.51 ENST00000265316.3
 ABCB6
 ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr6_+_36646435 0.51 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
 CDKN1A
 cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr12_+_49740700 0.50 ENST00000549441.2
ENST00000395069.3
 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
chr10_-_32217717 0.50 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
 ARHGAP12
 Rho GTPase activating protein 12
chr17_-_78194147 0.50 ENST00000534910.1
ENST00000326317.6
 SGSH
 N-sulfoglucosamine sulfohydrolase
chr13_-_33780133 0.50 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr2_-_100759037 0.49 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
 AFF3
 AF4/FMR2 family, member 3
chr7_+_73442422 0.49 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
 ELN
 elastin
chrX_+_37208521 0.48 ENST00000378628.4
 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
chr12_+_57849048 0.48 ENST00000266646.2
 INHBE
 inhibin, beta E
chr11_-_70507867 0.48 ENST00000412252.1
ENST00000409161.1
ENST00000409530.1
 SHANK2
 SH3 and multiple ankyrin repeat domains 2
chr11_-_73472096 0.48 ENST00000541588.1
ENST00000336083.3
ENST00000540771.1
ENST00000310653.6
 RAB6A
 RAB6A, member RAS oncogene family
chr22_+_24407776 0.48 ENST00000405822.2
 CABIN1
 calcineurin binding protein 1
chr12_-_71533055 0.47 ENST00000552128.1
 TSPAN8
 tetraspanin 8
chr15_+_66994561 0.47 ENST00000288840.5
 SMAD6
 SMAD family member 6
chr14_-_105420241 0.47 ENST00000557457.1
 AHNAK2
 AHNAK nucleoprotein 2
chr2_-_27341872 0.47 ENST00000312734.4
 CGREF1
 cell growth regulator with EF-hand domain 1
chr16_-_18468926 0.46 ENST00000545114.1
 RP11-1212A22.4
 LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr11_-_2950642 0.46 ENST00000314222.4
 PHLDA2
 pleckstrin homology-like domain, family A, member 2
chr22_+_24407847 0.46 ENST00000445422.1
ENST00000398319.2
 CABIN1
 calcineurin binding protein 1
chr9_+_137533615 0.46 ENST00000371817.3
 COL5A1
 collagen, type V, alpha 1
chr3_+_52009066 0.45 ENST00000458031.2
ENST00000463937.1
ENST00000273596.3
 ACY1
ABHD14A-ACY1
ABHD14A
 aminoacylase 1
ABHD14A-ACY1 readthrough (NMD candidate)
abhydrolase domain containing 14A

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 3.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0021564 vagus nerve development(GO:0021564)
1.7 5.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
1.1 4.5 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
1.0 6.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.0 2.9 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.9 2.8 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.9 3.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 4.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.9 7.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.8 2.4 GO:0033341 regulation of collagen binding(GO:0033341)
0.8 2.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.8 4.6 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.7 2.0 GO:0001300 chronological cell aging(GO:0001300)
0.6 1.9 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.6 5.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.6 1.8 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 2.2 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.5 1.6 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.5 1.6 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.5 1.6 GO:0006788 heme oxidation(GO:0006788)
0.5 0.5 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
0.5 1.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.4 2.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.4 1.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.4 1.5 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 2.0 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 2.8 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 0.9 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.3 1.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.3 1.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 0.8 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.3 1.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 0.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.7 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 0.7 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 0.7 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.2 0.6 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.2 0.6 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.2 1.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 4.5 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.2 2.2 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.2 4.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 2.0 GO:0015886 heme transport(GO:0015886)
0.2 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.7 GO:0048861 oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 2.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.0 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 0.8 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.2 0.5 GO:0035989 tendon development(GO:0035989)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.9 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.1 0.8 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 8.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 1.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.4 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.1 0.4 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) regulation of thyroid hormone generation(GO:2000609) positive regulation of thyroid hormone generation(GO:2000611)
0.1 1.0 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 0.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.5 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 0.3 GO:0060214 regulation of Wnt signaling pathway involved in heart development(GO:0003307) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996) endocardium formation(GO:0060214) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.1 0.5 GO:0030167 proteoglycan catabolic process(GO:0030167) heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.1 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.1 2.9 GO:0001945 lymph vessel development(GO:0001945)
0.1 0.4 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 1.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.1 1.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0000050 urea cycle(GO:0000050)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.1 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.3 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.3 GO:0009183 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.1 0.2 GO:0003306 Wnt signaling pathway involved in heart development(GO:0003306)
0.1 0.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.4 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 2.7 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.2 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1 0.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.5 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.9 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.4 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.1 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.2 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.8 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 3.1 GO:0035329 hippo signaling(GO:0035329)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 2.0 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.2 GO:0051462 cortisol secretion(GO:0043400) positive regulation of corticotropin secretion(GO:0051461) regulation of cortisol secretion(GO:0051462) cellular response to cocaine(GO:0071314) positive regulation of corticosterone secretion(GO:2000854)
0.1 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.9 GO:0003197 endocardial cushion development(GO:0003197)
0.1 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.2 GO:1990668 vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.1 1.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0090035 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.6 GO:0060004 reflex(GO:0060004)
0.0 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 1.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 1.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.4 GO:0090128 regulation of synapse maturation(GO:0090128)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 1.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0050955 thermoception(GO:0050955) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0044849 estrous cycle(GO:0044849)
0.0 0.0 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.8 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 6.8 GO:0007565 female pregnancy(GO:0007565)
0.0 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 3.6 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.4 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0071205 positive regulation of adenosine receptor signaling pathway(GO:0060168) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258) positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 1.2 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 0.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:1900120 regulation of receptor binding(GO:1900120)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.0 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:2000553 positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:0071621 granulocyte chemotaxis(GO:0071621)
0.0 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.5 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.4 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.2 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.0 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.0 5.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.0 2.9 GO:0035501 MH1 domain binding(GO:0035501)
0.7 2.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.7 2.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.6 1.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 2.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.5 2.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 1.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 1.4 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.4 1.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.4 1.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.4 1.6 GO:0038132 neuregulin binding(GO:0038132)
0.4 7.1 GO:0048185 activin binding(GO:0048185)
0.4 2.4 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3 1.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 5.8 GO:0051787 misfolded protein binding(GO:0051787)
0.3 2.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.2 0.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0004915 interleukin-6 receptor activity(GO:0004915) oncostatin-M receptor activity(GO:0004924) interleukin-6 binding(GO:0019981)
0.2 0.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.2 GO:0030332 cyclin binding(GO:0030332)
0.2 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 4.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.6 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 1.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.4 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.8 GO:0005119 smoothened binding(GO:0005119)
0.1 0.5 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 2.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 6.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 6.3 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 4.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 3.1 GO:0005319 lipid transporter activity(GO:0005319)
0.0 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 6.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 3.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.0 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0005607 laminin-2 complex(GO:0005607)
0.9 3.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.8 5.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.7 2.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.6 6.9 GO:0005614 interstitial matrix(GO:0005614)
0.6 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 2.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.5 4.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 2.1 GO:1990393 3M complex(GO:1990393)
0.4 3.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 6.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.3 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.3 2.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.9 GO:0071953 elastic fiber(GO:0071953)
0.2 2.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.9 GO:0043203 axon hillock(GO:0043203)
0.2 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 2.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.6 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.6 GO:0005883 neurofilament(GO:0005883)
0.1 0.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 6.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.0 GO:0033643 host cell part(GO:0033643)
0.1 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 3.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 5.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 3.4 GO:0005901 caveola(GO:0005901)
0.0 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 3.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.5 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 8.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 3.7 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 2.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0001726 ruffle(GO:0001726)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 7.4 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.3 PID BMP PATHWAY BMP receptor signaling
0.1 4.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.3 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 6.5 PID LKB1 PATHWAY LKB1 signaling events
0.1 4.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 0.8 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 3.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity