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ENCODE cell lines, expression (Ernst 2011)

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Results for ESR1

Z-value: 1.12

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ESR1
ENSG00000091831.17 ESR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152130240_1521302740.504.8e-02Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_106054659 2.80 ENST00000390539.2
 IGHA2
 immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_23165153 2.58 ENST00000390317.2
 IGLV2-8
 immunoglobulin lambda variable 2-8
chr22_+_23248512 2.34 ENST00000390325.2
 IGLC3
 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr22_+_23077065 2.19 ENST00000390310.2
 IGLV2-18
 immunoglobulin lambda variable 2-18
chr14_-_106209368 1.99 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
 IGHG1
 immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_23247030 1.98 ENST00000390324.2
 IGLJ3
 immunoglobulin lambda joining 3
chr15_+_89182178 1.89 ENST00000559876.1
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr22_+_22930626 1.86 ENST00000390302.2
 IGLV2-33
 immunoglobulin lambda variable 2-33 (non-functional)
chr10_+_115438920 1.76 ENST00000429617.1
ENST00000369331.4
 CASP7
 caspase 7, apoptosis-related cysteine peptidase
chr15_+_89181974 1.76 ENST00000306072.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr22_+_23243156 1.70 ENST00000390323.2
 IGLC2
 immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr15_+_89182156 1.67 ENST00000379224.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr11_+_1891380 1.66 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
 LSP1
 lymphocyte-specific protein 1
chr22_+_23241661 1.52 ENST00000390322.2
 IGLJ2
 immunoglobulin lambda joining 2
chr6_-_90121938 1.36 ENST00000369415.4
 RRAGD
 Ras-related GTP binding D
chr13_-_46964177 1.35 ENST00000389908.3
 KIAA0226L
 KIAA0226-like
chr22_+_22550113 1.33 ENST00000390285.3
 IGLV6-57
 immunoglobulin lambda variable 6-57
chr19_+_49838653 1.27 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
 CD37
 CD37 molecule
chr2_-_231090344 1.23 ENST00000540870.1
ENST00000416610.1
 SP110
 SP110 nuclear body protein
chr2_+_231090433 1.21 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
 SP140
 SP140 nuclear body protein
chr20_+_44441626 1.15 ENST00000372568.4
 UBE2C
 ubiquitin-conjugating enzyme E2C
chr17_-_39677971 1.12 ENST00000393976.2
 KRT15
 keratin 15
chr19_-_7764281 1.09 ENST00000360067.4
 FCER2
 Fc fragment of IgE, low affinity II, receptor for (CD23)
chr8_+_11351876 1.07 ENST00000529894.1
 BLK
 B lymphoid tyrosine kinase
chr14_+_106384295 1.07 ENST00000449410.1
ENST00000429431.1
 KIAA0125
 KIAA0125
chr8_+_11351494 1.06 ENST00000259089.4
 BLK
 B lymphoid tyrosine kinase
chr19_+_42381173 1.06 ENST00000221972.3
 CD79A
 CD79a molecule, immunoglobulin-associated alpha
chr14_-_106642049 1.05 ENST00000390605.2
 IGHV1-18
 immunoglobulin heavy variable 1-18
chr11_+_102188224 1.03 ENST00000263464.3
 BIRC3
 baculoviral IAP repeat containing 3
chr8_-_101348408 1.01 ENST00000519527.1
ENST00000522369.1
 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr11_+_102188272 1.00 ENST00000532808.1
 BIRC3
 baculoviral IAP repeat containing 3
chr18_+_56338618 0.99 ENST00000348428.3
 MALT1
 mucosa associated lymphoid tissue lymphoma translocation gene 1
chr20_+_49411523 0.98 ENST00000371608.2
 BCAS4
 breast carcinoma amplified sequence 4
chr2_-_38303218 0.96 ENST00000407341.1
ENST00000260630.3
 CYP1B1
 cytochrome P450, family 1, subfamily B, polypeptide 1
chr10_+_114135952 0.94 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
 ACSL5
 acyl-CoA synthetase long-chain family member 5
chr17_-_34207295 0.93 ENST00000463941.1
ENST00000293272.3
 CCL5
 chemokine (C-C motif) ligand 5
chr14_-_91884150 0.92 ENST00000553403.1
 CCDC88C
 coiled-coil domain containing 88C
chr17_+_65374075 0.92 ENST00000581322.1
 PITPNC1
 phosphatidylinositol transfer protein, cytoplasmic 1
chr18_+_21529811 0.90 ENST00000588004.1
 LAMA3
 laminin, alpha 3
chr16_+_50730910 0.86 ENST00000300589.2
 NOD2
 nucleotide-binding oligomerization domain containing 2
chr14_-_106471723 0.85 ENST00000390595.2
 IGHV1-3
 immunoglobulin heavy variable 1-3
chr22_-_23922410 0.81 ENST00000249053.3
 IGLL1
 immunoglobulin lambda-like polypeptide 1
chr19_-_10445399 0.80 ENST00000592945.1
 ICAM3
 intercellular adhesion molecule 3
chr3_+_121554046 0.80 ENST00000273668.2
ENST00000451944.2
 EAF2
 ELL associated factor 2
chr5_+_110559784 0.80 ENST00000282356.4
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr8_-_103136481 0.79 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
 NCALD
 neurocalcin delta
chr2_-_160761179 0.77 ENST00000554112.1
ENST00000553424.1
ENST00000263636.4
ENST00000504764.1
ENST00000505052.1
 LY75
LY75-CD302
 lymphocyte antigen 75
LY75-CD302 readthrough
chr5_-_73936451 0.77 ENST00000537006.1
 ENC1
 ectodermal-neural cortex 1 (with BTB domain)
chr1_-_209825674 0.74 ENST00000367030.3
ENST00000356082.4
 LAMB3
 laminin, beta 3
chr3_+_121774202 0.74 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
 CD86
 CD86 molecule
chr20_+_55204351 0.70 ENST00000201031.2
 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr10_+_112257596 0.68 ENST00000369583.3
 DUSP5
 dual specificity phosphatase 5
chr10_+_131265443 0.68 ENST00000306010.7
 MGMT
 O-6-methylguanine-DNA methyltransferase
chr17_+_42427826 0.66 ENST00000586443.1
 GRN
 granulin
chr4_-_10023095 0.65 ENST00000264784.3
 SLC2A9
 solute carrier family 2 (facilitated glucose transporter), member 9
chr6_-_41703296 0.65 ENST00000373033.1
 TFEB
 transcription factor EB
chr15_-_83621435 0.65 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
 HOMER2
 homer homolog 2 (Drosophila)
chr16_+_29690358 0.65 ENST00000395384.4
ENST00000562473.1
 QPRT
 quinolinate phosphoribosyltransferase
chr8_-_28243934 0.64 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
 ZNF395
 zinc finger protein 395
chrX_-_1571759 0.63 ENST00000381317.3
ENST00000416733.2
 ASMTL
 acetylserotonin O-methyltransferase-like
chr15_-_20170354 0.63 ENST00000338912.5
 IGHV1OR15-9
 immunoglobulin heavy variable 1/OR15-9 (non-functional)
chrX_-_1571810 0.61 ENST00000381333.4
 ASMTL
 acetylserotonin O-methyltransferase-like
chr6_+_24495067 0.61 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
 ALDH5A1
 aldehyde dehydrogenase 5 family, member A1
chr19_+_39279838 0.60 ENST00000314980.4
 LGALS7B
 lectin, galactoside-binding, soluble, 7B
chr14_-_106725723 0.60 ENST00000390609.2
 IGHV3-23
 immunoglobulin heavy variable 3-23
chr1_+_153003671 0.60 ENST00000307098.4
 SPRR1B
 small proline-rich protein 1B
chr5_+_110559603 0.56 ENST00000512453.1
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr13_+_103451399 0.55 ENST00000257336.1
ENST00000448849.2
 BIVM
 basic, immunoglobulin-like variable motif containing
chr16_-_21289627 0.55 ENST00000396023.2
ENST00000415987.2
 CRYM
 crystallin, mu
chr2_-_98612350 0.54 ENST00000186436.5
 TMEM131
 transmembrane protein 131
chr8_-_28243590 0.53 ENST00000523095.1
ENST00000522795.1
 ZNF395
 zinc finger protein 395
chr5_-_150466692 0.53 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
 TNIP1
 TNFAIP3 interacting protein 1
chr22_-_23922448 0.52 ENST00000438703.1
ENST00000330377.2
 IGLL1
 immunoglobulin lambda-like polypeptide 1
chr19_-_18717627 0.52 ENST00000392386.3
 CRLF1
 cytokine receptor-like factor 1
chr9_-_112260531 0.52 ENST00000374541.2
ENST00000262539.3
 PTPN3
 protein tyrosine phosphatase, non-receptor type 3
chr19_-_6720686 0.51 ENST00000245907.6
 C3
 complement component 3
chr22_-_24096562 0.51 ENST00000398465.3
 VPREB3
 pre-B lymphocyte 3
chr4_-_155511887 0.50 ENST00000302053.3
ENST00000403106.3
 FGA
 fibrinogen alpha chain
chr2_-_242041607 0.50 ENST00000434791.1
ENST00000401626.2
ENST00000439144.1
ENST00000406593.1
ENST00000495694.1
ENST00000407095.3
ENST00000391980.2
 MTERFD2
 MTERF domain containing 2
chr18_-_7117813 0.49 ENST00000389658.3
 LAMA1
 laminin, alpha 1
chr4_-_103266219 0.48 ENST00000394833.2
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr3_-_121553830 0.48 ENST00000498104.1
ENST00000460108.1
ENST00000349820.6
ENST00000462442.1
ENST00000310864.6
 IQCB1
 IQ motif containing B1
chr17_-_41739283 0.47 ENST00000393661.2
ENST00000318579.4
 MEOX1
 mesenchyme homeobox 1
chr7_-_1980128 0.47 ENST00000437877.1
 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
chr12_+_54378923 0.47 ENST00000303460.4
 HOXC10
 homeobox C10
chr2_-_89292422 0.46 ENST00000495489.1
 IGKV1-8
 immunoglobulin kappa variable 1-8
chr1_+_9711781 0.46 ENST00000536656.1
ENST00000377346.4
 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chrX_-_107019181 0.45 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
 TSC22D3
 TSC22 domain family, member 3
chr9_+_128509663 0.45 ENST00000373489.5
ENST00000373483.2
 PBX3
 pre-B-cell leukemia homeobox 3
chr22_-_24096630 0.45 ENST00000248948.3
 VPREB3
 pre-B lymphocyte 3
chr2_+_233925064 0.45 ENST00000359570.5
ENST00000538935.1
 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
chr14_-_106453155 0.45 ENST00000390594.2
 IGHV1-2
 immunoglobulin heavy variable 1-2
chr22_+_22681656 0.45 ENST00000390291.2
 IGLV1-50
 immunoglobulin lambda variable 1-50 (non-functional)
chr8_+_26371763 0.44 ENST00000521913.1
 DPYSL2
 dihydropyrimidinase-like 2
chr1_-_236445251 0.43 ENST00000354619.5
ENST00000327333.8
 ERO1LB
 ERO1-like beta (S. cerevisiae)
chr6_-_112115074 0.43 ENST00000368667.2
 FYN
 FYN oncogene related to SRC, FGR, YES
chr11_+_75526212 0.42 ENST00000356136.3
 UVRAG
 UV radiation resistance associated
chr20_+_61287711 0.42 ENST00000370507.1
 SLCO4A1
 solute carrier organic anion transporter family, member 4A1
chr1_-_16763911 0.41 ENST00000375577.1
ENST00000335496.1
 SPATA21
 spermatogenesis associated 21
chr11_+_69924639 0.40 ENST00000538023.1
ENST00000398543.2
 ANO1
 anoctamin 1, calcium activated chloride channel
chr8_-_101571964 0.40 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
 ANKRD46
 ankyrin repeat domain 46
chr15_+_81489213 0.38 ENST00000559383.1
ENST00000394660.2
 IL16
 interleukin 16
chr14_+_105992906 0.38 ENST00000392519.2
 TMEM121
 transmembrane protein 121
chr2_+_219283815 0.38 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
 VIL1
 villin 1
chr8_+_17780346 0.38 ENST00000325083.8
 PCM1
 pericentriolar material 1
chr14_-_107078851 0.38 ENST00000390628.2
 IGHV1-58
 immunoglobulin heavy variable 1-58
chr17_-_41738931 0.38 ENST00000329168.3
ENST00000549132.1
 MEOX1
 mesenchyme homeobox 1
chr12_+_6603253 0.37 ENST00000382457.4
ENST00000545962.1
 NCAPD2
 non-SMC condensin I complex, subunit D2
chr4_+_4388805 0.37 ENST00000504171.1
 NSG1
 Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr7_-_134896234 0.37 ENST00000354475.4
ENST00000344400.5
 WDR91
 WD repeat domain 91
chr17_-_36348610 0.36 ENST00000339023.4
ENST00000354664.4
 TBC1D3
 TBC1 domain family, member 3
chr8_-_71316021 0.36 ENST00000452400.2
 NCOA2
 nuclear receptor coactivator 2
chrX_-_106959631 0.36 ENST00000486554.1
ENST00000372390.4
 TSC22D3
 TSC22 domain family, member 3
chr10_-_52645379 0.36 ENST00000395489.2
 A1CF
 APOBEC1 complementation factor
chr8_+_17780483 0.36 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
 PCM1
 pericentriolar material 1
chr11_+_32851487 0.35 ENST00000257836.3
 PRRG4
 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr22_+_22735135 0.35 ENST00000390297.2
 IGLV1-44
 immunoglobulin lambda variable 1-44
chr2_+_11679963 0.35 ENST00000263834.5
 GREB1
 growth regulation by estrogen in breast cancer 1
chr10_-_52645416 0.34 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
 A1CF
 APOBEC1 complementation factor
chr17_-_34757039 0.34 ENST00000455054.2
ENST00000308078.7
 TBC1D3H
TBC1D3C
 TBC1 domain family, member 3H
TBC1 domain family, member 3C
chr2_-_89513402 0.34 ENST00000498435.1
 IGKV1-27
 immunoglobulin kappa variable 1-27
chr17_-_27507377 0.34 ENST00000531253.1
 MYO18A
 myosin XVIIIA
chr2_+_234627424 0.34 ENST00000373409.3
 UGT1A4
 UDP glucuronosyltransferase 1 family, polypeptide A4
chr9_-_120177342 0.33 ENST00000361209.2
 ASTN2
 astrotactin 2
chr11_+_3876859 0.33 ENST00000300737.4
 STIM1
 stromal interaction molecule 1
chr17_+_36283971 0.33 ENST00000327454.6
ENST00000378174.5
 TBC1D3F
 TBC1 domain family, member 3F
chr3_-_47205457 0.33 ENST00000409792.3
 SETD2
 SET domain containing 2
chr5_-_16509101 0.32 ENST00000399793.2
 FAM134B
 family with sequence similarity 134, member B
chr11_+_46740730 0.32 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
 F2
 coagulation factor II (thrombin)
chr3_-_15469006 0.32 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
 METTL6
 methyltransferase like 6
chr5_+_175223715 0.32 ENST00000515502.1
 CPLX2
 complexin 2
chr19_+_35759824 0.32 ENST00000343550.5
 USF2
 upstream transcription factor 2, c-fos interacting
chr11_-_615570 0.31 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
 IRF7
 interferon regulatory factor 7
chr5_+_110074685 0.31 ENST00000355943.3
ENST00000447245.2
 SLC25A46
 solute carrier family 25, member 46
chr1_-_154832316 0.31 ENST00000361147.4
 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr8_-_131028641 0.31 ENST00000523509.1
 FAM49B
 family with sequence similarity 49, member B
chr2_-_68479614 0.31 ENST00000234310.3
 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
chr17_-_27507395 0.30 ENST00000354329.4
ENST00000527372.1
 MYO18A
 myosin XVIIIA
chr2_+_234600253 0.30 ENST00000373424.1
ENST00000441351.1
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr7_+_115850547 0.30 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
 TES
 testis derived transcript (3 LIM domains)
chr20_-_45981138 0.30 ENST00000446994.2
 ZMYND8
 zinc finger, MYND-type containing 8
chr5_+_142149932 0.30 ENST00000274498.4
 ARHGAP26
 Rho GTPase activating protein 26
chr11_+_123396528 0.30 ENST00000322282.7
ENST00000529750.1
 GRAMD1B
 GRAM domain containing 1B
chr13_-_99174252 0.30 ENST00000376547.3
 STK24
 serine/threonine kinase 24
chr2_+_71295416 0.30 ENST00000455662.2
ENST00000531934.1
 NAGK
 N-acetylglucosamine kinase
chr8_-_131028660 0.29 ENST00000401979.2
ENST00000517654.1
ENST00000522361.1
ENST00000518167.1
 FAM49B
 family with sequence similarity 49, member B
chr14_+_106355918 0.29 ENST00000414005.1
 AL122127.25
 AL122127.25
chr17_+_26698677 0.29 ENST00000457710.3
 SARM1
 sterile alpha and TIR motif containing 1
chr17_-_34592032 0.29 ENST00000457979.3
 TBC1D3C
 TBC1 domain family, member 3C
chr22_-_51016433 0.28 ENST00000405237.3
 CPT1B
 carnitine palmitoyltransferase 1B (muscle)
chr8_+_82192501 0.28 ENST00000297258.6
 FABP5
 fatty acid binding protein 5 (psoriasis-associated)
chr17_+_55173933 0.28 ENST00000539273.1
 AKAP1
 A kinase (PRKA) anchor protein 1
chr15_-_64338521 0.28 ENST00000457488.1
ENST00000558069.1
 DAPK2
 death-associated protein kinase 2
chr22_+_39853258 0.28 ENST00000341184.6
 MGAT3
 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_201252580 0.28 ENST00000367324.3
ENST00000263946.3
 PKP1
 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr14_+_77790901 0.27 ENST00000553586.1
ENST00000555583.1
 GSTZ1
 glutathione S-transferase zeta 1
chr2_+_234621551 0.27 ENST00000608381.1
ENST00000373414.3
 UGT1A1
UGT1A5
 UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr17_-_34808047 0.27 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
 TBC1D3G
TBC1D3H
 TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr16_-_51185172 0.27 ENST00000251020.4
 SALL1
 spalt-like transcription factor 1
chr7_-_99569468 0.27 ENST00000419575.1
 AZGP1
 alpha-2-glycoprotein 1, zinc-binding
chr1_-_111970353 0.26 ENST00000369732.3
 OVGP1
 oviductal glycoprotein 1, 120kDa
chr19_-_17375541 0.26 ENST00000252597.3
 USHBP1
 Usher syndrome 1C binding protein 1
chr12_+_16064106 0.26 ENST00000428559.2
 DERA
 deoxyribose-phosphate aldolase (putative)
chr5_-_131347501 0.26 ENST00000543479.1
 ACSL6
 acyl-CoA synthetase long-chain family member 6
chr14_+_90422239 0.26 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
 TDP1
 tyrosyl-DNA phosphodiesterase 1
chr6_-_109777128 0.26 ENST00000358807.3
ENST00000358577.3
 MICAL1
 microtubule associated monooxygenase, calponin and LIM domain containing 1
chr19_-_46148820 0.26 ENST00000587152.1
 EML2
 echinoderm microtubule associated protein like 2
chr11_+_2923619 0.26 ENST00000380574.1
 SLC22A18
 solute carrier family 22, member 18
chr22_-_21579843 0.25 ENST00000405188.4
 GGT2
 gamma-glutamyltransferase 2
chr6_+_80816342 0.25 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
 BCKDHB
 branched chain keto acid dehydrogenase E1, beta polypeptide
chr8_+_42010464 0.25 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
 AP3M2
 adaptor-related protein complex 3, mu 2 subunit
chr20_+_32581525 0.25 ENST00000246194.3
ENST00000413297.1
 RALY
 RALY heterogeneous nuclear ribonucleoprotein
chr5_+_142149955 0.25 ENST00000378004.3
 ARHGAP26
 Rho GTPase activating protein 26
chr12_-_108733078 0.25 ENST00000552995.1
ENST00000312143.7
ENST00000397688.2
ENST00000550402.1
 CMKLR1
 chemokine-like receptor 1
chr1_-_24151903 0.24 ENST00000436439.2
ENST00000374490.3
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr16_+_56995854 0.24 ENST00000566128.1
 CETP
 cholesteryl ester transfer protein, plasma
chrX_-_13062752 0.24 ENST00000380625.3
ENST00000542843.1
 FAM9C
 family with sequence similarity 9, member C
chr3_-_13461807 0.24 ENST00000254508.5
 NUP210
 nucleoporin 210kDa
chr19_-_14048804 0.24 ENST00000254320.3
ENST00000586075.1
 PODNL1
 podocan-like 1
chr4_-_130692631 0.23 ENST00000500092.2
ENST00000509105.1
 RP11-519M16.1
 RP11-519M16.1
chr2_-_28113965 0.23 ENST00000302188.3
 RBKS
 ribokinase
chr1_-_24151892 0.23 ENST00000235958.4
 HMGCL
 3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr20_+_61584026 0.23 ENST00000370351.4
ENST00000370349.3
 SLC17A9
 solute carrier family 17 (vesicular nucleotide transporter), member 9
chr20_+_45947246 0.23 ENST00000599904.1
 AL031666.2
 HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr13_-_52027134 0.23 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6
 integrator complex subunit 6
chr15_+_75335604 0.23 ENST00000563393.1
 PPCDC
 phosphopantothenoylcysteine decarboxylase
chr11_-_1036706 0.22 ENST00000421673.2
 MUC6
 mucin 6, oligomeric mucus/gel-forming
chr3_-_52488048 0.22 ENST00000232975.3
 TNNC1
 troponin C type 1 (slow)
chr5_-_1112141 0.22 ENST00000264930.5
 SLC12A7
 solute carrier family 12 (potassium/chloride transporter), member 7
chr3_+_58223228 0.22 ENST00000478253.1
ENST00000295962.4
 ABHD6
 abhydrolase domain containing 6
chr21_-_45660840 0.22 ENST00000400377.3
 ICOSLG
 inducible T-cell co-stimulator ligand
chr3_+_9404526 0.22 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
 THUMPD3
 THUMP domain containing 3
chr19_-_22379753 0.21 ENST00000397121.2
 ZNF676
 zinc finger protein 676
chr12_+_16064258 0.21 ENST00000524480.1
ENST00000531803.1
ENST00000532964.1
 DERA
 deoxyribose-phosphate aldolase (putative)
chr14_+_100485712 0.21 ENST00000544450.2
 EVL
 Enah/Vasp-like
chr6_-_27799305 0.21 ENST00000357549.2
 HIST1H4K
 histone cluster 1, H4k
chr14_+_23776167 0.21 ENST00000554635.1
ENST00000557008.1
 BCL2L2
BCL2L2-PABPN1
 BCL2-like 2
BCL2L2-PABPN1 readthrough
chr20_-_62168672 0.21 ENST00000217185.2
 PTK6
 protein tyrosine kinase 6
chr5_-_66492562 0.21 ENST00000256447.4
 CD180
 CD180 molecule
chr17_-_5026397 0.21 ENST00000250076.3
 ZNF232
 zinc finger protein 232

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.6 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2 9.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.1 GO:0019863 IgE binding(GO:0019863)
0.1 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.6 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.3 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.3 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 1.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 1.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.0 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 7.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.9 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0071748 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.2 0.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 1.4 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.6 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.0 GO:0032449 CBM complex(GO:0032449)
0.2 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.5 GO:0005608 laminin-3 complex(GO:0005608)
0.2 1.1 GO:0019815 B cell receptor complex(GO:0019815)
0.1 6.8 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 5.4 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 2.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.3 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 2.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.3 1.0 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 2.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 0.7 GO:0042109 negative regulation of tolerance induction(GO:0002644) lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 1.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.4 GO:0071233 cellular response to leucine(GO:0071233)
0.2 1.8 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 1.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.2 0.9 GO:0061056 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.2 1.4 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.2 0.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.5 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 2.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 0.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 1.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0060374 mast cell differentiation(GO:0060374)
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0006789 bilirubin conjugation(GO:0006789)
0.1 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.8 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.6 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 6.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.6 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 0.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.3 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.3 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.3 GO:0097676 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.1 0.3 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.7 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 0.5 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.3 GO:0051801 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:0043315 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 2.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.7 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 1.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.3 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.5 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 3.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 5.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 1.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0045084 positive regulation of Schwann cell differentiation(GO:0014040) positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 1.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0072535 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.3 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0042325 regulation of phosphorylation(GO:0042325)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)