ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
FOSL1 Links Ensembl NCBI GeneCards UniProt	ENSG00000175592.4	FOSL1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOSL1	hg19_v2_chr11_-_65667997_65668044	0.90	2.8e-06	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr18_+_21452804	20.52	ENST00000269217.6	LAMA3	laminin, alpha 3
chr18_+_21452964	18.15	ENST00000587184.1	LAMA3	laminin, alpha 3
chr1_-_95007193	15.85	ENST00000370207.4 ENST00000334047.7	F3	coagulation factor III (thromboplastin, tissue factor)
chr1_-_151965048	15.01	ENST00000368809.1	S100A10	S100 calcium binding protein A10
chr1_+_223889285	14.35	ENST00000433674.2	CAPN2	calpain 2, (m/II) large subunit
chr3_-_151034734	12.76	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr17_-_39743139	12.68	ENST00000167586.6	KRT14	keratin 14
chr1_+_183155373	12.41	ENST00000493293.1 ENST00000264144.4	LAMC2	laminin, gamma 2
chr12_+_13349650	12.15	ENST00000256951.5 ENST00000431267.2 ENST00000542474.1 ENST00000544053.1	EMP1	epithelial membrane protein 1
chr10_+_17270214	12.11	ENST00000544301.1	VIM	vimentin
chr17_-_39769005	11.58	ENST00000301653.4 ENST00000593067.1	KRT16	keratin 16
chr18_+_61554932	9.25	ENST00000299502.4 ENST00000457692.1 ENST00000413956.1	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr17_-_39780819	9.12	ENST00000311208.8	KRT17	keratin 17
chr1_+_153003671	8.95	ENST00000307098.4	SPRR1B	small proline-rich protein 1B
chr4_+_169753156	8.70	ENST00000393726.3 ENST00000507735.1	PALLD	palladin, cytoskeletal associated protein
chr11_-_6341844	8.41	ENST00000303927.3	PRKCDBP	protein kinase C, delta binding protein
chr11_-_102668879	8.08	ENST00000315274.6	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr1_+_27189631	7.76	ENST00000339276.4	SFN	stratifin
chr11_-_2950642	7.69	ENST00000314222.4	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr18_+_61442629	7.49	ENST00000398019.2 ENST00000540675.1	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_+_55177416	7.40	ENST00000450046.1 ENST00000454757.2	EGFR	epidermal growth factor receptor
chr2_-_166651191	7.32	ENST00000392701.3	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr6_-_138428613	7.15	ENST00000421351.3	PERP	PERP, TP53 apoptosis effector
chr1_+_223900034	7.14	ENST00000295006.5	CAPN2	calpain 2, (m/II) large subunit
chr1_-_209824643	6.61	ENST00000391911.1 ENST00000415782.1	LAMB3	laminin, beta 3
chr6_+_83072923	6.43	ENST00000535040.1	TPBG	trophoblast glycoprotein
chr18_+_61143994	6.30	ENST00000382771.4	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr11_+_35198243	6.24	ENST00000528455.1	CD44	CD44 molecule (Indian blood group)
chr11_-_6341724	6.16	ENST00000530979.1	PRKCDBP	protein kinase C, delta binding protein
chr6_+_125540951	5.97	ENST00000524679.1	TPD52L1	tumor protein D52-like 1
chr1_+_152956549	5.93	ENST00000307122.2	SPRR1A	small proline-rich protein 1A
chr1_-_152009460	5.60	ENST00000271638.2	S100A11	S100 calcium binding protein A11
chr11_+_394196	5.50	ENST00000331563.2 ENST00000531857.1	PKP3	plakophilin 3
chr19_+_39279838	5.33	ENST00000314980.4	LGALS7B	lectin, galactoside-binding, soluble, 7B
chr7_+_48128194	5.20	ENST00000416681.1 ENST00000331803.4 ENST00000432131.1	UPP1	uridine phosphorylase 1
chr19_+_35645817	5.17	ENST00000423817.3	FXYD5	FXYD domain containing ion transport regulator 5
chr7_+_48128316	5.13	ENST00000341253.4	UPP1	uridine phosphorylase 1
chr11_-_65667997	4.94	ENST00000312562.2 ENST00000534222.1	FOSL1	FOS-like antigen 1
chr19_+_35645618	4.83	ENST00000392218.2 ENST00000543307.1 ENST00000392219.2 ENST00000541435.2 ENST00000590686.1 ENST00000342879.3 ENST00000588699.1	FXYD5	FXYD domain containing ion transport regulator 5
chr5_+_135394840	4.82	ENST00000503087.1	TGFBI	transforming growth factor, beta-induced, 68kDa
chr1_+_152881014	4.78	ENST00000368764.3 ENST00000392667.2	IVL	involucrin
chr6_-_84140757	4.72	ENST00000541327.1 ENST00000369705.3 ENST00000543031.1	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_35198118	4.59	ENST00000525211.1 ENST00000526000.1 ENST00000279452.6 ENST00000527889.1	CD44	CD44 molecule (Indian blood group)
chr1_+_150480576	4.53	ENST00000346569.6	ECM1	extracellular matrix protein 1
chr1_+_150480551	4.51	ENST00000369049.4 ENST00000369047.4	ECM1	extracellular matrix protein 1
chr11_+_35639735	4.41	ENST00000317811.4	FJX1	four jointed box 1 (Drosophila)
chr19_-_51523275	4.33	ENST00000309958.3	KLK10	kallikrein-related peptidase 10
chr1_+_35220613	4.31	ENST00000338513.1	GJB5	gap junction protein, beta 5, 31.1kDa
chr19_-_51523412	4.22	ENST00000391805.1 ENST00000599077.1	KLK10	kallikrein-related peptidase 10
chr11_-_65667884	4.04	ENST00000448083.2 ENST00000531493.1 ENST00000532401.1	FOSL1	FOS-like antigen 1
chrX_-_10851762	3.90	ENST00000380785.1 ENST00000380787.1	MID1	midline 1 (Opitz/BBB syndrome)
chr20_+_4666882	3.83	ENST00000379440.4 ENST00000430350.2	PRNP	prion protein
chr3_+_30647994	3.79	ENST00000295754.5	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr13_-_110438914	3.68	ENST00000375856.3	IRS2	insulin receptor substrate 2
chr10_+_121410882	3.66	ENST00000369085.3	BAG3	BCL2-associated athanogene 3
chr1_-_113247543	3.66	ENST00000414971.1 ENST00000534717.1	RHOC	ras homolog family member C
chr11_+_101983176	3.64	ENST00000524575.1	YAP1	Yes-associated protein 1
chr3_+_30648066	3.56	ENST00000359013.4	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr20_+_4667094	3.45	ENST00000424424.1 ENST00000457586.1	PRNP	prion protein
chr11_+_114310237	3.43	ENST00000539119.1	REXO2	RNA exonuclease 2
chr1_-_159894319	3.38	ENST00000320307.4	TAGLN2	transgelin 2
chr1_+_36621697	3.27	ENST00000373150.4 ENST00000373151.2	MAP7D1	MAP7 domain containing 1
chr3_-_32022733	3.27	ENST00000438237.2 ENST00000396556.2	OSBPL10	oxysterol binding protein-like 10
chr1_-_154943002	3.15	ENST00000606391.1	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr17_+_35851570	3.11	ENST00000394386.1	DUSP14	dual specificity phosphatase 14
chr4_-_114900831	3.07	ENST00000315366.7	ARSJ	arylsulfatase family, member J
chr1_+_36621529	2.92	ENST00000316156.4	MAP7D1	MAP7 domain containing 1
chr15_+_41136586	2.92	ENST00000431806.1	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr7_+_23286182	2.92	ENST00000258733.4 ENST00000381990.2 ENST00000409458.3 ENST00000539136.1 ENST00000453162.2	GPNMB	glycoprotein (transmembrane) nmb
chr13_+_78109804	2.89	ENST00000535157.1	SCEL	sciellin
chr5_+_35856951	2.89	ENST00000303115.3 ENST00000343305.4 ENST00000506850.1 ENST00000511982.1	IL7R	interleukin 7 receptor
chr13_+_78109884	2.88	ENST00000377246.3 ENST00000349847.3	SCEL	sciellin
chr3_-_48632593	2.87	ENST00000454817.1 ENST00000328333.8	COL7A1	collagen, type VII, alpha 1
chr5_-_1882858	2.80	ENST00000511126.1 ENST00000231357.2	IRX4	iroquois homeobox 4
chr1_-_154943212	2.79	ENST00000368445.5 ENST00000448116.2 ENST00000368449.4	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr12_-_54813229	2.74	ENST00000293379.4	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr20_+_33759854	2.72	ENST00000216968.4	PROCR	protein C receptor, endothelial
chr1_+_26605618	2.70	ENST00000270792.5	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr15_-_60690163	2.67	ENST00000558998.1 ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2	ANXA2	annexin A2
chr21_-_36421535	2.60	ENST00000416754.1 ENST00000437180.1 ENST00000455571.1	RUNX1	runt-related transcription factor 1
chr21_-_36421626	2.58	ENST00000300305.3	RUNX1	runt-related transcription factor 1
chr18_+_61637159	2.46	ENST00000397985.2 ENST00000353706.2 ENST00000542677.1 ENST00000397988.3 ENST00000448851.1	SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr1_+_156095951	2.46	ENST00000448611.2 ENST00000368297.1	LMNA	lamin A/C
chr11_-_66103867	2.45	ENST00000424433.2	RIN1	Ras and Rab interactor 1
chr2_-_85641162	2.43	ENST00000447219.2 ENST00000409670.1 ENST00000409724.1	CAPG	capping protein (actin filament), gelsolin-like
chr5_-_134914673	2.36	ENST00000512158.1	CXCL14	chemokine (C-X-C motif) ligand 14
chr15_+_41136216	2.29	ENST00000562057.1 ENST00000344051.4	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr7_+_116312411	2.27	ENST00000456159.1 ENST00000397752.3 ENST00000318493.6	MET	met proto-oncogene
chr17_+_74381343	2.25	ENST00000392496.3	SPHK1	sphingosine kinase 1
chr17_+_73717551	2.25	ENST00000450894.3	ITGB4	integrin, beta 4
chrX_+_12993202	2.19	ENST00000451311.2 ENST00000380636.1	TMSB4X	thymosin beta 4, X-linked
chr7_+_134528635	2.16	ENST00000445569.2	CALD1	caldesmon 1
chr1_+_26606608	2.12	ENST00000319041.6	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr3_-_18466026	2.09	ENST00000417717.2	SATB1	SATB homeobox 1
chr12_-_56122761	2.06	ENST00000552164.1 ENST00000420846.3 ENST00000257857.4	CD63	CD63 molecule
chr1_-_153013588	2.03	ENST00000360379.3	SPRR2D	small proline-rich protein 2D
chr14_+_96722152	1.95	ENST00000216629.6	BDKRB1	bradykinin receptor B1
chr5_+_140729649	1.94	ENST00000523390.1	PCDHGB1	protocadherin gamma subfamily B, 1
chr16_+_57662138	1.93	ENST00000562414.1 ENST00000561969.1 ENST00000562631.1 ENST00000563445.1 ENST00000565338.1 ENST00000567702.1	GPR56	G protein-coupled receptor 56
chr16_+_57662419	1.90	ENST00000388812.4 ENST00000538815.1 ENST00000456916.1 ENST00000567154.1 ENST00000388813.5 ENST00000562558.1 ENST00000566271.2	GPR56	G protein-coupled receptor 56
chr17_-_39942940	1.89	ENST00000310706.5 ENST00000393931.3 ENST00000424457.1 ENST00000591690.1	JUP	junction plakoglobin
chr16_+_30751953	1.89	ENST00000483578.1	RP11-2C24.4	RP11-2C24.4
chr12_-_15114603	1.88	ENST00000228945.4	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr11_-_108408895	1.88	ENST00000443411.1 ENST00000533052.1	EXPH5	exophilin 5
chr17_+_73717407	1.87	ENST00000579662.1	ITGB4	integrin, beta 4
chr3_-_18466787	1.82	ENST00000338745.6 ENST00000450898.1	SATB1	SATB homeobox 1
chr11_-_111783919	1.81	ENST00000531198.1 ENST00000533879.1	CRYAB	crystallin, alpha B
chr15_+_40531621	1.78	ENST00000560346.1	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr10_+_1102721	1.77	ENST00000263150.4	WDR37	WD repeat domain 37
chr11_-_111794446	1.75	ENST00000527950.1	CRYAB	crystallin, alpha B
chr1_-_153066998	1.73	ENST00000368750.3	SPRR2E	small proline-rich protein 2E
chr1_-_153521597	1.67	ENST00000368712.1	S100A3	S100 calcium binding protein A3
chr7_-_107643674	1.67	ENST00000222399.6	LAMB1	laminin, beta 1
chr15_+_40531243	1.65	ENST00000558055.1 ENST00000455577.2	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr19_-_45927622	1.60	ENST00000300853.3 ENST00000589165.1	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr5_+_140868717	1.60	ENST00000252087.1	PCDHGC5	protocadherin gamma subfamily C, 5
chr11_-_64013663	1.57	ENST00000392210.2	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_42276612	1.56	ENST00000395925.3 ENST00000437480.1	GLI3	GLI family zinc finger 3
chr11_+_706113	1.56	ENST00000318562.8 ENST00000533256.1 ENST00000534755.1	EPS8L2	EPS8-like 2
chr21_-_27543425	1.54	ENST00000448388.2	APP	amyloid beta (A4) precursor protein
chr1_-_153029980	1.54	ENST00000392653.2	SPRR2A	small proline-rich protein 2A
chrX_-_48937531	1.53	ENST00000473974.1 ENST00000475880.1 ENST00000396681.4 ENST00000553851.1 ENST00000471338.1 ENST00000476728.1 ENST00000376368.2 ENST00000485908.1 ENST00000376372.3 ENST00000376358.3	WDR45 AF196779.12	WD repeat domain 45 WD repeat domain phosphoinositide-interacting protein 4
chr1_+_156096336	1.48	ENST00000504687.1 ENST00000473598.2	LMNA	lamin A/C
chr16_-_122619	1.44	ENST00000262316.6	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr17_+_73717516	1.43	ENST00000200181.3 ENST00000339591.3	ITGB4	integrin, beta 4
chr21_-_27542972	1.38	ENST00000346798.3 ENST00000439274.2 ENST00000354192.3 ENST00000348990.5 ENST00000357903.3 ENST00000358918.3 ENST00000359726.3	APP	amyloid beta (A4) precursor protein
chr16_+_15596123	1.35	ENST00000452191.2	C16orf45	chromosome 16 open reading frame 45
chr3_-_169587621	1.34	ENST00000523069.1 ENST00000316428.5 ENST00000264676.5	LRRC31	leucine rich repeat containing 31
chr5_-_141061777	1.32	ENST00000239440.4	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_-_153521714	1.30	ENST00000368713.3	S100A3	S100 calcium binding protein A3
chr12_-_56236690	1.28	ENST00000322569.4	MMP19	matrix metallopeptidase 19
chr1_-_93257951	1.28	ENST00000543509.1 ENST00000370331.1 ENST00000540033.1	EVI5	ecotropic viral integration site 5
chr9_-_35112376	1.27	ENST00000488109.2	FAM214B	family with sequence similarity 214, member B
chr3_-_37216055	1.24	ENST00000336686.4	LRRFIP2	leucine rich repeat (in FLII) interacting protein 2
chr17_-_27503770	1.24	ENST00000533112.1	MYO18A	myosin XVIIIA
chr5_-_141061759	1.20	ENST00000508305.1	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_-_48937503	1.16	ENST00000322995.8	WDR45	WD repeat domain 45
chr1_-_6662919	1.13	ENST00000377658.4 ENST00000377663.3	KLHL21	kelch-like family member 21
chr4_+_74606223	1.11	ENST00000307407.3 ENST00000401931.1	IL8	interleukin 8
chr16_+_66968343	1.09	ENST00000417689.1 ENST00000561697.1 ENST00000317091.4 ENST00000566182.1	CES2	carboxylesterase 2
chr19_-_44285401	1.08	ENST00000262888.3	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_-_91573249	1.07	ENST00000550099.1 ENST00000546391.1 ENST00000551354.1	DCN	decorin
chr3_-_149095652	1.04	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr9_+_140135665	1.03	ENST00000340384.4	TUBB4B	tubulin, beta 4B class IVb
chr2_+_33359687	1.01	ENST00000402934.1 ENST00000404525.1 ENST00000407925.1	LTBP1	latent transforming growth factor beta binding protein 1
chr11_-_64013288	1.01	ENST00000542235.1	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_33359646	1.00	ENST00000390003.4 ENST00000418533.2	LTBP1	latent transforming growth factor beta binding protein 1
chr12_-_91573316	0.99	ENST00000393155.1	DCN	decorin
chr19_+_36630454	0.98	ENST00000246533.3	CAPNS1	calpain, small subunit 1
chr14_-_75643296	0.97	ENST00000303575.4	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chrX_-_153285395	0.96	ENST00000369980.3	IRAK1	interleukin-1 receptor-associated kinase 1
chr16_+_89988259	0.95	ENST00000554444.1 ENST00000556565.1	TUBB3	Tubulin beta-3 chain
chr17_-_65362678	0.95	ENST00000357146.4 ENST00000356126.3	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr3_+_69134124	0.95	ENST00000478935.1	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr6_-_159239257	0.93	ENST00000337147.7 ENST00000392177.4	EZR	ezrin
chr3_+_69928256	0.92	ENST00000394355.2	MITF	microphthalmia-associated transcription factor
chr11_-_111784005	0.92	ENST00000527899.1	CRYAB	crystallin, alpha B
chr19_+_36630855	0.89	ENST00000589146.1	CAPNS1	calpain, small subunit 1
chr8_+_26150628	0.89	ENST00000523925.1 ENST00000315985.7	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr2_+_191792376	0.88	ENST00000409428.1 ENST00000409215.1	GLS	glutaminase
chr7_+_90338712	0.88	ENST00000265741.3 ENST00000406263.1	CDK14	cyclin-dependent kinase 14
chr21_-_36421401	0.86	ENST00000486278.2	RUNX1	runt-related transcription factor 1
chr2_+_102618428	0.85	ENST00000457817.1	IL1R2	interleukin 1 receptor, type II
chr3_-_122512619	0.83	ENST00000383659.1 ENST00000306103.2	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr3_+_69134080	0.83	ENST00000273258.3	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr8_+_24771265	0.82	ENST00000518131.1 ENST00000437366.2	NEFM	neurofilament, medium polypeptide
chr19_+_36630961	0.82	ENST00000587718.1 ENST00000592483.1 ENST00000590874.1 ENST00000588815.1	CAPNS1	calpain, small subunit 1
chr15_+_40532058	0.82	ENST00000260404.4	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr17_+_30771279	0.81	ENST00000261712.3 ENST00000578213.1 ENST00000457654.2 ENST00000579451.1	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_+_183894566	0.81	ENST00000439647.1	AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr11_-_66104237	0.80	ENST00000530056.1	RIN1	Ras and Rab interactor 1
chr1_-_52344471	0.79	ENST00000352171.7 ENST00000354831.7	NRD1	nardilysin (N-arginine dibasic convertase)
chrX_-_48901012	0.78	ENST00000315869.7	TFE3	transcription factor binding to IGHM enhancer 3
chr3_+_187930719	0.78	ENST00000312675.4	LPP	LIM domain containing preferred translocation partner in lipoma
chr11_-_66103932	0.78	ENST00000311320.4	RIN1	Ras and Rab interactor 1
chr22_+_45072925	0.77	ENST00000006251.7	PRR5	proline rich 5 (renal)
chr22_+_45072958	0.76	ENST00000403581.1	PRR5	proline rich 5 (renal)
chr17_-_73781567	0.75	ENST00000586607.1	H3F3B	H3 histone, family 3B (H3.3B)
chr14_+_94492674	0.73	ENST00000203664.5 ENST00000553723.1	OTUB2	OTU domain, ubiquitin aldehyde binding 2
chr17_-_73775839	0.73	ENST00000592643.1 ENST00000591890.1 ENST00000587171.1 ENST00000254810.4 ENST00000589599.1	H3F3B	H3 histone, family 3B (H3.3B)
chr9_-_35111570	0.72	ENST00000378561.1 ENST00000603301.1	FAM214B	family with sequence similarity 214, member B
chrX_-_153285251	0.72	ENST00000444230.1 ENST00000393682.1 ENST00000393687.2 ENST00000429936.2 ENST00000369974.2	IRAK1	interleukin-1 receptor-associated kinase 1
chr12_+_9142131	0.72	ENST00000356986.3 ENST00000266551.4	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr12_-_91573132	0.71	ENST00000550563.1 ENST00000546370.1	DCN	decorin
chr1_+_156084461	0.71	ENST00000347559.2 ENST00000361308.4 ENST00000368300.4 ENST00000368299.3	LMNA	lamin A/C
chr22_+_22707260	0.70	ENST00000390293.1	IGLV5-48	immunoglobulin lambda variable 5-48 (non-functional)
chr12_+_110718921	0.69	ENST00000308664.6	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr12_+_10365404	0.69	ENST00000266458.5 ENST00000421801.2 ENST00000544284.1 ENST00000545047.1 ENST00000543602.1 ENST00000545887.1	GABARAPL1	GABA(A) receptor-associated protein like 1
chr2_+_47596287	0.69	ENST00000263735.4	EPCAM	epithelial cell adhesion molecule
chr13_-_103719196	0.69	ENST00000245312.3	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr17_+_79650962	0.68	ENST00000329138.4	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_+_138089100	0.66	ENST00000520339.1 ENST00000355078.5 ENST00000302763.7 ENST00000518910.1	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr15_-_56209306	0.65	ENST00000506154.1 ENST00000338963.2 ENST00000508342.1	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr12_-_56122426	0.64	ENST00000551173.1	CD63	CD63 molecule
chr12_+_10366016	0.64	ENST00000546017.1 ENST00000535576.1 ENST00000539170.1	GABARAPL1	GABA(A) receptor-associated protein like 1
chr19_+_45973120	0.64	ENST00000592811.1 ENST00000586615.1	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr22_-_30642782	0.63	ENST00000249075.3	LIF	leukemia inhibitory factor
chr13_+_53602894	0.63	ENST00000219022.2	OLFM4	olfactomedin 4
chrX_-_15511438	0.62	ENST00000380420.5	PIR	pirin (iron-binding nuclear protein)
chr16_+_74330673	0.61	ENST00000219313.4 ENST00000540379.1 ENST00000567958.1 ENST00000568615.2	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	64.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	36.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	5.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	25.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	10.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	17.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.3	10.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	22.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	22.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	3.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	6.8	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	5.5	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	4.0	PID RAS PATHWAY	Regulation of Ras family activation
0.1	4.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	21.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	0.9	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	7.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	2.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	9.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	2.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.8	PID ARF 3PATHWAY	Arf1 pathway
0.0	12.0	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.0	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	15.9	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
3.3	10.0	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
2.6	75.9	GO:0031581	hemidesmosome assembly(GO:0031581)
2.6	10.3	GO:0046108	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
2.5	7.4	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
2.4	7.3	GO:0002663	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
2.4	7.3	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.9	7.5	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
1.8	7.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
1.6	4.8	GO:0018262	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
1.6	7.8	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
1.5	9.0	GO:0007296	vitellogenesis(GO:0007296)
1.5	7.4	GO:0002159	desmosome assembly(GO:0002159)
1.4	10.8	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.2	4.9	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.2	7.2	GO:0002934	desmosome organization(GO:0002934)
1.1	21.6	GO:0045109	intermediate filament organization(GO:0045109)
1.0	18.9	GO:0016540	protein autoprocessing(GO:0016540)
0.9	12.2	GO:0051546	keratinocyte migration(GO:0051546)
0.9	4.6	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.9	3.7	GO:1903960	regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.9	2.7	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.8	15.0	GO:0001765	membrane raft assembly(GO:0001765)
0.8	4.7	GO:0006741	NADP biosynthetic process(GO:0006741)
0.8	2.3	GO:0046521	sphingoid catabolic process(GO:0046521)
0.7	3.6	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.7	12.1	GO:0032060	bleb assembly(GO:0032060)
0.7	4.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.6	7.7	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.6	3.7	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.6	11.8	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.6	2.9	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.5	1.6	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.5	9.6	GO:0003334	keratinocyte development(GO:0003334)
0.5	2.3	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4	1.8	GO:0071461	cellular response to redox state(GO:0071461)
0.4	1.7	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4	1.2	GO:1903028	positive regulation of opsonization(GO:1903028)
0.4	22.9	GO:0018149	peptide cross-linking(GO:0018149)
0.4	2.4	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4	2.2	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.4	9.0	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.4	2.5	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.3	0.7	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	2.7	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.3	1.3	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.3	0.7	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.3	5.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	0.6	GO:0044111	development involved in symbiotic interaction(GO:0044111)
0.3	1.0	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.3	9.3	GO:0042730	fibrinolysis(GO:0042730)
0.3	3.9	GO:0035372	protein localization to microtubule(GO:0035372)
0.3	2.9	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.3	1.6	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.2	4.5	GO:0007021	tubulin complex assembly(GO:0007021)
0.2	3.9	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	1.0	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2	3.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	2.0	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2	1.8	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.2	0.8	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2	2.7	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2	2.5	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.2	1.9	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.2	0.9	GO:0022614	membrane to membrane docking(GO:0022614) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.2	0.7	GO:0035871	protein K11-linked deubiquitination(GO:0035871) protein K63-linked deubiquitination(GO:0070536)
0.2	0.5	GO:0035938	estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.2	2.7	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.2	0.9	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	5.9	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2	3.7	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2	11.1	GO:0030574	collagen catabolic process(GO:0030574)
0.2	4.4	GO:0010842	retina layer formation(GO:0010842)
0.2	2.4	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.1	5.6	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.1	3.3	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1	1.0	GO:0042325	regulation of phosphorylation(GO:0042325)
0.1	1.5	GO:0038203	TORC2 signaling(GO:0038203)
0.1	0.4	GO:0038178	complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1	0.4	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.1	0.6	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	2.9	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.1	1.1	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	0.6	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.5	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1	1.9	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.1	6.3	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	1.3	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	5.0	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.1	0.3	GO:0005986	sucrose biosynthetic process(GO:0005986)
0.1	2.7	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	4.9	GO:0030834	regulation of actin filament depolymerization(GO:0030834)
0.1	0.3	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1	0.2	GO:1901656	glycoside transport(GO:1901656)
0.1	0.3	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1	0.5	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.9	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	1.8	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.1	0.5	GO:0071724	toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1	2.1	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1	0.1	GO:1900040	regulation of interleukin-2 secretion(GO:1900040) positive regulation of interleukin-2 secretion(GO:1900042)
0.1	0.2	GO:1904383	response to sodium phosphate(GO:1904383) response to insulin-like growth factor stimulus(GO:1990418)
0.0	0.3	GO:1990182	exosomal secretion(GO:1990182)
0.0	0.1	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0	6.1	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	0.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.7	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	1.1	GO:0044380	protein localization to cytoskeleton(GO:0044380)
0.0	0.4	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.3	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.0	0.0	GO:1990737	response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0	0.3	GO:2000507	cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507)
0.0	0.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.5	GO:0043248	proteasome assembly(GO:0043248)
0.0	2.4	GO:0009798	axis specification(GO:0009798)
0.0	0.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:0006196	AMP catabolic process(GO:0006196)
0.0	1.3	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.6	GO:0051412	response to corticosterone(GO:0051412)
0.0	3.2	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	1.0	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.8	GO:0006959	humoral immune response(GO:0006959)
0.0	2.7	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	1.0	GO:0006692	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	2.2	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.6	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.9	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.6	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	5.4	GO:0043406	positive regulation of MAP kinase activity(GO:0043406)
0.0	0.3	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.0	0.6	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.6	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.2	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.4	GO:0010863	positive regulation of phospholipase C activity(GO:0010863)
0.0	0.5	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	0.5	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.5	GO:0007249	I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	1.0	GO:0050709	negative regulation of protein secretion(GO:0050709)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	45.3	GO:0005610	laminin-5 complex(GO:0005610)
4.7	14.1	GO:0005607	laminin-2 complex(GO:0005607)
2.5	7.4	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
2.0	5.9	GO:0070435	Shc-EGFR complex(GO:0070435)
1.5	10.8	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
1.0	23.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.8	15.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.8	7.3	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8	7.2	GO:0030057	desmosome(GO:0030057)
0.7	3.6	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.7	38.1	GO:0001533	cornified envelope(GO:0001533)
0.7	2.7	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.5	2.7	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.5	4.6	GO:0005638	lamin filament(GO:0005638)
0.5	9.0	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	1.3	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.4	42.2	GO:0005882	intermediate filament(GO:0005882)
0.4	3.9	GO:0097449	astrocyte projection(GO:0097449)
0.3	5.5	GO:0030056	hemidesmosome(GO:0030056)
0.3	1.7	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.3	2.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.3	4.5	GO:0097512	cardiac myofibril(GO:0097512)
0.3	1.8	GO:0070545	PeBoW complex(GO:0070545)
0.3	4.3	GO:0005922	connexon complex(GO:0005922)
0.2	1.6	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2	0.7	GO:0033565	ESCRT-0 complex(GO:0033565)
0.2	2.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.8	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2	2.4	GO:0008290	F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.1	7.6	GO:0002102	podosome(GO:0002102)
0.1	2.2	GO:0030478	actin cap(GO:0030478)
0.1	2.9	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	1.1	GO:0005827	polar microtubule(GO:0005827)
0.1	2.7	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	1.0	GO:0097470	ribbon synapse(GO:0097470)
0.1	3.7	GO:0032420	stereocilium(GO:0032420)
0.1	2.0	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.5	GO:0031932	TORC2 complex(GO:0031932)
0.1	3.9	GO:0005720	nuclear heterochromatin(GO:0005720)
0.1	1.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	7.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	7.9	GO:0042734	presynaptic membrane(GO:0042734)
0.1	0.5	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.1	0.7	GO:0005915	zonula adherens(GO:0005915)
0.1	5.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.8	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	3.9	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	4.8	GO:0005604	basement membrane(GO:0005604)
0.1	12.5	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.4	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.3	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.0	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	1.6	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0032437	cuticular plate(GO:0032437)
0.0	2.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.6	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.9	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	5.2	GO:0030027	lamellipodium(GO:0030027)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	4.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0097433	dense body(GO:0097433)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	4.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.4	GO:0031461	cullin-RING ubiquitin ligase complex(GO:0031461)
0.0	1.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.6	GO:0035580	specific granule lumen(GO:0035580)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	3.7	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.7	10.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.6	10.8	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.5	63.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.5	13.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.5	12.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	15.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.3	7.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.3	8.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	3.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.3	4.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.2	4.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	8.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	2.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.7	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	5.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	6.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.1	7.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	2.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	3.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	6.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	2.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	5.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	0.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.1	1.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.7	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	1.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.0	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	2.8	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	4.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	3.7	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	24.8	GO:1990254	keratin filament binding(GO:1990254)
2.6	7.8	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
2.6	10.3	GO:0004850	uridine phosphorylase activity(GO:0004850)
1.9	13.3	GO:0048408	epidermal growth factor binding(GO:0048408)
1.8	7.3	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
1.8	9.1	GO:0042289	MHC class II protein binding(GO:0042289)
1.4	8.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
1.2	7.3	GO:1903135	cupric ion binding(GO:1903135)
1.0	2.9	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.8	4.7	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.7	2.1	GO:0004947	bradykinin receptor activity(GO:0004947)
0.6	11.8	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5	7.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.5	14.5	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5	20.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5	7.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4	2.0	GO:0050436	microfibril binding(GO:0050436)
0.4	2.3	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3	10.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.3	7.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	3.7	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	32.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.3	5.5	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.3	2.9	GO:0045545	syndecan binding(GO:0045545)
0.3	2.7	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.3	3.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	1.7	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.2	1.6	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2	0.9	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.2	3.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.2	1.1	GO:0047374	methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2	1.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.2	1.9	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2	3.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	2.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2	1.8	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	0.9	GO:0004359	glutaminase activity(GO:0004359)
0.2	9.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.2	0.8	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	0.5	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.4	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.1	1.9	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.6	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	3.7	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	2.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	1.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	6.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	2.7	GO:0070064	proline-rich region binding(GO:0070064)
0.1	2.7	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.3	GO:0030957	Tat protein binding(GO:0030957)
0.1	13.0	GO:0002020	protease binding(GO:0002020)
0.1	2.2	GO:0005523	tropomyosin binding(GO:0005523)
0.1	75.1	GO:0005198	structural molecule activity(GO:0005198)
0.1	9.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.1	GO:0048156	tau protein binding(GO:0048156)
0.1	0.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.3	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	4.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0005150	interleukin-1, Type I receptor binding(GO:0005150)
0.1	10.1	GO:0044325	ion channel binding(GO:0044325)
0.1	3.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.6	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	2.6	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	7.5	GO:0008201	heparin binding(GO:0008201)
0.1	1.8	GO:0003785	actin monomer binding(GO:0003785)
0.1	1.9	GO:0008009	chemokine activity(GO:0008009)
0.1	1.2	GO:0070888	E-box binding(GO:0070888)
0.1	0.4	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1	0.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.0	3.0	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.4	GO:0036122	BMP binding(GO:0036122)
0.0	3.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	1.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	1.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.4	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	2.2	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.6	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.2	GO:0043531	ADP binding(GO:0043531)
0.0	0.1	GO:0003998	acylphosphatase activity(GO:0003998)
0.0	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.4	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.0	1.9	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.3	GO:0019903	protein phosphatase binding(GO:0019903)