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ENCODE cell lines, expression (Ernst 2011)

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Results for FOXA3_FOXC2

Z-value: 0.76

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.2 FOXA3
FOXC2
ENSG00000176692.4 FOXC2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC2hg19_v2_chr16_+_86600857_86600921-0.448.9e-02Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_116708302 4.42 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
 APOA1
 apolipoprotein A-I
chr17_+_79953310 4.23 ENST00000582355.2
 ASPSCR1
 alveolar soft part sarcoma chromosome region, candidate 1
chr17_-_26694979 3.71 ENST00000438614.1
 VTN
 vitronectin
chr17_-_26695013 3.68 ENST00000555059.2
 CTB-96E2.2
 Homeobox protein SEBOX
chr6_-_41715128 3.62 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
 PGC
 progastricsin (pepsinogen C)
chr1_-_169555779 2.91 ENST00000367797.3
ENST00000367796.3
 F5
 coagulation factor V (proaccelerin, labile factor)
chr17_+_72426891 2.87 ENST00000392627.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr2_+_128175997 2.50 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
 PROC
 protein C (inactivator of coagulation factors Va and VIIIa)
chr2_-_21266935 2.44 ENST00000233242.1
 APOB
 apolipoprotein B
chr8_+_97597148 2.35 ENST00000521590.1
 SDC2
 syndecan 2
chr14_+_21156915 2.02 ENST00000397990.4
ENST00000555597.1
 ANG
RNASE4
 angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr22_+_21128167 1.93 ENST00000215727.5
 SERPIND1
 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_+_74269956 1.88 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
 ALB
 albumin
chr2_+_58655461 1.70 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
 AC007092.1
 long intergenic non-protein coding RNA 1122
chr14_-_94789663 1.68 ENST00000557225.1
ENST00000341584.3
 SERPINA6
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr1_-_146696901 1.31 ENST00000369272.3
ENST00000441068.2
 FMO5
 flavin containing monooxygenase 5
chr14_-_25479811 1.24 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr18_-_25616519 1.13 ENST00000399380.3
 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
chr17_-_39684550 1.04 ENST00000455635.1
ENST00000361566.3
 KRT19
 keratin 19
chr4_-_70080449 0.99 ENST00000446444.1
 UGT2B11
 UDP glucuronosyltransferase 2 family, polypeptide B11
chrX_+_9431324 0.97 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr7_+_134832808 0.94 ENST00000275767.3
 TMEM140
 transmembrane protein 140
chr17_+_72427477 0.93 ENST00000342648.5
ENST00000481232.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr1_-_57431679 0.79 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
 C8B
 complement component 8, beta polypeptide
chr11_-_115375107 0.78 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chrX_-_20236970 0.75 ENST00000379548.4
 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_187187098 0.73 ENST00000403665.2
ENST00000264692.4
 F11
 coagulation factor XI
chr14_-_38064198 0.69 ENST00000250448.2
 FOXA1
 forkhead box A1
chr7_-_107643674 0.68 ENST00000222399.6
 LAMB1
 laminin, beta 1
chr1_+_207277590 0.67 ENST00000367070.3
 C4BPA
 complement component 4 binding protein, alpha
chr9_-_75567962 0.66 ENST00000297785.3
ENST00000376939.1
 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
chr7_-_22259845 0.65 ENST00000420196.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr16_-_87970122 0.64 ENST00000309893.2
 CA5A
 carbonic anhydrase VA, mitochondrial
chr4_+_79567314 0.63 ENST00000503539.1
ENST00000504675.1
 RP11-792D21.2
 long intergenic non-protein coding RNA 1094
chr18_-_52626622 0.63 ENST00000591504.1
 CCDC68
 coiled-coil domain containing 68
chr17_-_26697304 0.61 ENST00000536498.1
 VTN
 vitronectin
chr2_+_220042933 0.57 ENST00000430297.2
 FAM134A
 family with sequence similarity 134, member A
chr20_+_44519948 0.57 ENST00000354880.5
ENST00000191018.5
 CTSA
 cathepsin A
chr4_+_79567362 0.57 ENST00000512322.1
 RP11-792D21.2
 long intergenic non-protein coding RNA 1094
chr20_+_44520009 0.55 ENST00000607482.1
ENST00000372459.2
 CTSA
 cathepsin A
chr21_-_43786634 0.54 ENST00000291527.2
 TFF1
 trefoil factor 1
chr20_+_45338126 0.53 ENST00000359271.2
 SLC2A10
 solute carrier family 2 (facilitated glucose transporter), member 10
chr14_+_74034310 0.53 ENST00000538782.1
 ACOT2
 acyl-CoA thioesterase 2
chr4_-_186696425 0.51 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
 SORBS2
 sorbin and SH3 domain containing 2
chr6_+_10528560 0.50 ENST00000379597.3
 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr3_-_99833333 0.47 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
 FILIP1L
 filamin A interacting protein 1-like
chr16_-_15474904 0.47 ENST00000534094.1
 NPIPA5
 nuclear pore complex interacting protein family, member A5
chr16_+_14802801 0.47 ENST00000526520.1
ENST00000531598.2
 NPIPA3
 nuclear pore complex interacting protein family, member A3
chr17_+_4613776 0.44 ENST00000269260.2
 ARRB2
 arrestin, beta 2
chr5_+_156712372 0.44 ENST00000541131.1
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr1_+_73771844 0.42 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
 RP4-598G3.1
 RP4-598G3.1
chr19_+_782755 0.41 ENST00000606242.1
ENST00000586061.1
 AC006273.5
 AC006273.5
chr17_+_4613918 0.40 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
 ARRB2
 arrestin, beta 2
chrX_+_23352133 0.40 ENST00000379361.4
 PTCHD1
 patched domain containing 1
chr10_-_63995871 0.39 ENST00000315289.2
 RTKN2
 rhotekin 2
chr20_+_11898507 0.37 ENST00000378226.2
 BTBD3
 BTB (POZ) domain containing 3
chr7_+_112063192 0.36 ENST00000005558.4
 IFRD1
 interferon-related developmental regulator 1
chr12_+_120740119 0.35 ENST00000536460.1
ENST00000202967.4
 SIRT4
 sirtuin 4
chr17_+_74372662 0.33 ENST00000591651.1
ENST00000545180.1
 SPHK1
 sphingosine kinase 1
chr19_+_15160130 0.31 ENST00000427043.3
 CASP14
 caspase 14, apoptosis-related cysteine peptidase
chr14_-_74551096 0.31 ENST00000350259.4
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr2_-_165424973 0.31 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr1_-_151431909 0.31 ENST00000361398.3
ENST00000271715.2
 POGZ
 pogo transposable element with ZNF domain
chr20_-_43150601 0.31 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
 SERINC3
 serine incorporator 3
chr1_+_114471972 0.31 ENST00000369559.4
ENST00000369554.2
 HIPK1
 homeodomain interacting protein kinase 1
chr14_-_74551172 0.30 ENST00000553458.1
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr3_-_114343039 0.30 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr20_+_44035200 0.28 ENST00000372717.1
ENST00000360981.4
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_-_46615498 0.28 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
 AMBRA1
 autophagy/beclin-1 regulator 1
chr1_+_114471809 0.27 ENST00000426820.2
 HIPK1
 homeodomain interacting protein kinase 1
chr4_-_140223670 0.27 ENST00000394228.1
ENST00000539387.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_73242490 0.27 ENST00000431918.1
 CLDN4
 claudin 4
chr1_-_151431647 0.26 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
 POGZ
 pogo transposable element with ZNF domain
chr14_+_23299088 0.25 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
 MRPL52
 mitochondrial ribosomal protein L52
chr2_-_175260368 0.25 ENST00000342016.3
ENST00000362053.5
 CIR1
 corepressor interacting with RBPJ, 1
chrX_+_107288197 0.25 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr6_+_158733692 0.24 ENST00000367094.2
ENST00000367097.3
 TULP4
 tubby like protein 4
chr3_-_105588231 0.23 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr2_+_113885138 0.23 ENST00000409930.3
 IL1RN
 interleukin 1 receptor antagonist
chr17_-_202579 0.23 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
 RPH3AL
 rabphilin 3A-like (without C2 domains)
chr4_-_140223614 0.22 ENST00000394223.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_+_138943265 0.21 ENST00000483726.1
 UBN2
 ubinuclein 2
chr5_-_115872142 0.21 ENST00000510263.1
 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_-_73848086 0.21 ENST00000536168.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr12_+_58087901 0.21 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
 OS9
 osteosarcoma amplified 9, endoplasmic reticulum lectin
chr20_+_44035847 0.21 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_-_98262240 0.21 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chrX_+_107288239 0.20 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr6_-_122792919 0.19 ENST00000339697.4
 SERINC1
 serine incorporator 1
chr2_-_65593784 0.19 ENST00000443619.2
 SPRED2
 sprouty-related, EVH1 domain containing 2
chr8_-_28243934 0.19 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
 ZNF395
 zinc finger protein 395
chr7_+_134576317 0.19 ENST00000424922.1
ENST00000495522.1
 CALD1
 caldesmon 1
chr16_+_77233294 0.18 ENST00000378644.4
 SYCE1L
 synaptonemal complex central element protein 1-like
chr3_+_142315225 0.17 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chr7_+_28452130 0.17 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chr10_-_46030841 0.17 ENST00000453424.2
 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr12_-_71551652 0.17 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr1_+_29563011 0.16 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
 PTPRU
 protein tyrosine phosphatase, receptor type, U
chr1_-_150669604 0.16 ENST00000427665.1
ENST00000540514.1
 GOLPH3L
 golgi phosphoprotein 3-like
chr14_-_31926701 0.16 ENST00000310850.4
 DTD2
 D-tyrosyl-tRNA deacylase 2 (putative)
chr12_+_59989791 0.16 ENST00000552432.1
 SLC16A7
 solute carrier family 16 (monocarboxylate transporter), member 7
chr16_-_86542455 0.16 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
 FENDRR
 FOXF1 adjacent non-coding developmental regulatory RNA
chr19_-_46088068 0.15 ENST00000263275.4
ENST00000323060.3
 OPA3
 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr19_+_47421933 0.15 ENST00000404338.3
 ARHGAP35
 Rho GTPase activating protein 35
chr7_-_121784285 0.15 ENST00000417368.2
 AASS
 aminoadipate-semialdehyde synthase
chr7_-_25268104 0.15 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr4_+_184365744 0.15 ENST00000504169.1
ENST00000302350.4
 CDKN2AIP
 CDKN2A interacting protein
chr1_-_152332480 0.15 ENST00000388718.5
 FLG2
 filaggrin family member 2
chr1_+_154540246 0.14 ENST00000368476.3
 CHRNB2
 cholinergic receptor, nicotinic, beta 2 (neuronal)
chr14_+_20811722 0.14 ENST00000429687.3
 PARP2
 poly (ADP-ribose) polymerase 2
chr16_+_20775358 0.13 ENST00000440284.2
 ACSM3
 acyl-CoA synthetase medium-chain family member 3
chr6_-_25830785 0.13 ENST00000468082.1
 SLC17A1
 solute carrier family 17 (organic anion transporter), member 1
chr1_-_223308098 0.13 ENST00000342210.6
 TLR5
 toll-like receptor 5
chr7_+_134430212 0.13 ENST00000436461.2
 CALD1
 caldesmon 1
chr12_+_72080253 0.13 ENST00000549735.1
 TMEM19
 transmembrane protein 19
chr14_+_20811766 0.12 ENST00000250416.5
ENST00000527915.1
 PARP2
 poly (ADP-ribose) polymerase 2
chr7_-_107443652 0.12 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
 SLC26A3
 solute carrier family 26 (anion exchanger), member 3
chr4_+_118955500 0.12 ENST00000296499.5
 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr7_+_95115210 0.12 ENST00000428113.1
ENST00000325885.5
 ASB4
 ankyrin repeat and SOCS box containing 4
chr6_-_13621126 0.12 ENST00000600057.1
 AL441883.1
 Uncharacterized protein
chr3_-_186080012 0.12 ENST00000544847.1
ENST00000265022.3
 DGKG
 diacylglycerol kinase, gamma 90kDa
chr10_+_123923105 0.12 ENST00000368999.1
 TACC2
 transforming, acidic coiled-coil containing protein 2
chr8_+_67579807 0.12 ENST00000519289.1
ENST00000519561.1
ENST00000521889.1
 C8orf44-SGK3
C8orf44
 C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr19_-_15443318 0.11 ENST00000360016.5
 BRD4
 bromodomain containing 4
chr11_-_82708519 0.11 ENST00000534301.1
 RAB30
 RAB30, member RAS oncogene family
chr6_-_26056695 0.11 ENST00000343677.2
 HIST1H1C
 histone cluster 1, H1c
chrX_+_65382381 0.10 ENST00000519389.1
 HEPH
 hephaestin
chr2_+_136343820 0.10 ENST00000410054.1
 R3HDM1
 R3H domain containing 1
chr6_+_108882069 0.10 ENST00000406360.1
 FOXO3
 forkhead box O3
chr1_-_28384598 0.10 ENST00000373864.1
 EYA3
 eyes absent homolog 3 (Drosophila)
chr2_-_183291741 0.10 ENST00000351439.5
ENST00000409365.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr6_+_44355257 0.10 ENST00000371477.3
 CDC5L
 cell division cycle 5-like
chrX_+_24167746 0.10 ENST00000428571.1
ENST00000539115.1
 ZFX
 zinc finger protein, X-linked
chr3_+_171561127 0.10 ENST00000334567.5
ENST00000450693.1
 TMEM212
 transmembrane protein 212
chr5_-_58571935 0.09 ENST00000503258.1
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr8_-_120651020 0.09 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_28974603 0.09 ENST00000441461.1
ENST00000358506.2
 PPP1CB
 protein phosphatase 1, catalytic subunit, beta isozyme
chr16_+_69958887 0.09 ENST00000568684.1
 WWP2
 WW domain containing E3 ubiquitin protein ligase 2
chr4_+_88720698 0.09 ENST00000226284.5
 IBSP
 integrin-binding sialoprotein
chr7_+_106505696 0.09 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr15_-_66797172 0.09 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
 RPL4
 ribosomal protein L4
chr1_+_87797351 0.09 ENST00000370542.1
 LMO4
 LIM domain only 4
chr3_+_141106643 0.09 ENST00000514251.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr8_-_80993010 0.08 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
 TPD52
 tumor protein D52
chr1_+_150488205 0.08 ENST00000416894.1
 LINC00568
 long intergenic non-protein coding RNA 568
chr6_-_49755019 0.08 ENST00000304801.3
 PGK2
 phosphoglycerate kinase 2
chr16_+_67381263 0.08 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
 LRRC36
 leucine rich repeat containing 36
chr1_+_18958008 0.08 ENST00000420770.2
ENST00000400661.3
 PAX7
 paired box 7
chr8_+_19171128 0.08 ENST00000265807.3
 SH2D4A
 SH2 domain containing 4A
chr5_-_24645078 0.08 ENST00000264463.4
 CDH10
 cadherin 10, type 2 (T2-cadherin)
chr4_-_116034979 0.08 ENST00000264363.2
 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr14_+_37126765 0.08 ENST00000402703.2
 PAX9
 paired box 9
chr6_+_161123270 0.08 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
 PLG
 plasminogen
chr2_-_86422523 0.07 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
 IMMT
 inner membrane protein, mitochondrial
chrX_+_24167828 0.07 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
 ZFX
 zinc finger protein, X-linked
chr1_+_18957500 0.07 ENST00000375375.3
 PAX7
 paired box 7
chrX_+_99839799 0.07 ENST00000373031.4
 TNMD
 tenomodulin
chr3_+_148447887 0.07 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
 AGTR1
 angiotensin II receptor, type 1
chr3_-_113897899 0.07 ENST00000383673.2
ENST00000295881.7
 DRD3
 dopamine receptor D3
chr11_-_82708435 0.06 ENST00000525117.1
ENST00000532548.1
 RAB30
 RAB30, member RAS oncogene family
chr3_+_137728842 0.06 ENST00000183605.5
 CLDN18
 claudin 18
chr3_+_35721106 0.06 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr9_-_95186739 0.06 ENST00000375550.4
 OMD
 osteomodulin
chr5_+_74807886 0.06 ENST00000514296.1
 POLK
 polymerase (DNA directed) kappa
chr5_+_161494770 0.06 ENST00000414552.2
ENST00000361925.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr19_+_41257084 0.06 ENST00000601393.1
 SNRPA
 small nuclear ribonucleoprotein polypeptide A
chr2_+_162272605 0.06 ENST00000389554.3
 TBR1
 T-box, brain, 1
chr21_-_36259445 0.06 ENST00000399240.1
 RUNX1
 runt-related transcription factor 1
chr7_+_134576151 0.06 ENST00000393118.2
 CALD1
 caldesmon 1
chr13_-_36429763 0.05 ENST00000379893.1
 DCLK1
 doublecortin-like kinase 1
chr18_-_31803169 0.05 ENST00000590712.1
 NOL4
 nucleolar protein 4
chr6_-_24666819 0.05 ENST00000341060.3
 TDP2
 tyrosyl-DNA phosphodiesterase 2
chr11_-_72070206 0.05 ENST00000544382.1
 CLPB
 ClpB caseinolytic peptidase B homolog (E. coli)
chr17_-_36358166 0.05 ENST00000537432.1
 TBC1D3
 TBC1 domain family, member 3
chr6_+_52051171 0.05 ENST00000340057.1
 IL17A
 interleukin 17A
chr3_+_148545586 0.05 ENST00000282957.4
ENST00000468341.1
 CPB1
 carboxypeptidase B1 (tissue)
chr7_+_106505912 0.05 ENST00000359195.3
 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr9_+_131062367 0.04 ENST00000601297.1
 AL359091.2
 CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr12_-_102591604 0.04 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr2_+_28974668 0.04 ENST00000296122.6
ENST00000395366.2
 PPP1CB
 protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_174933899 0.04 ENST00000367688.3
 RABGAP1L
 RAB GTPase activating protein 1-like
chr16_+_67381289 0.04 ENST00000435835.3
 LRRC36
 leucine rich repeat containing 36
chr14_+_56127989 0.04 ENST00000555573.1
 KTN1
 kinectin 1 (kinesin receptor)
chr14_-_24664540 0.04 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr8_-_95449155 0.03 ENST00000481490.2
 FSBP
 fibrinogen silencer binding protein
chr5_-_59481406 0.03 ENST00000546160.1
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr15_-_40600026 0.03 ENST00000456256.2
ENST00000557821.1
 PLCB2
 phospholipase C, beta 2
chr5_+_161495038 0.03 ENST00000393933.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr14_-_36990354 0.03 ENST00000518149.1
 NKX2-1
 NK2 homeobox 1
chr4_-_174256276 0.03 ENST00000296503.5
 HMGB2
 high mobility group box 2
chr13_+_52598827 0.03 ENST00000521776.2
 UTP14C
 UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr8_+_75736761 0.03 ENST00000260113.2
 PI15
 peptidase inhibitor 15
chr6_+_72922505 0.02 ENST00000401910.3
 RIMS1
 regulating synaptic membrane exocytosis 1
chr5_+_140787600 0.02 ENST00000520790.1
 PCDHGB6
 protocadherin gamma subfamily B, 6
chrX_-_55020511 0.02 ENST00000375006.3
ENST00000374992.2
 PFKFB1
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_+_72922590 0.02 ENST00000523963.1
 RIMS1
 regulating synaptic membrane exocytosis 1
chr7_-_81399329 0.02 ENST00000453411.1
ENST00000444829.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_87804815 0.02 ENST00000369582.2
 CGA
 glycoprotein hormones, alpha polypeptide
chr12_-_53207842 0.02 ENST00000458244.2
 KRT4
 keratin 4
chr18_+_61575200 0.02 ENST00000238508.3
 SERPINB10
 serpin peptidase inhibitor, clade B (ovalbumin), member 10

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 2.4 GO:0035473 lipase binding(GO:0035473)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 0.8 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.3 4.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 3.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 1.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.2 GO:0005507 copper ion binding(GO:0005507)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 6.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.1 4.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 2.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 2.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 0.7 GO:0005607 laminin-2 complex(GO:0005607)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.2 1.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 1.1 GO:0016342 catenin complex(GO:0016342)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 6.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 4.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0044218 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 6.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 4.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.8 2.5 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.6 1.9 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.6 4.3 GO:0008218 bioluminescence(GO:0008218)
0.6 3.6 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.6 2.9 GO:0032571 response to vitamin K(GO:0032571)
0.5 4.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.4 2.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 2.4 GO:0034371 triglyceride mobilization(GO:0006642) response to selenium ion(GO:0010269) chylomicron remodeling(GO:0034371)
0.2 1.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.8 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 0.8 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.2 0.6 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.7 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.6 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 1.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 4.6 GO:0046323 glucose import(GO:0046323)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.0 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.9 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)