ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
FOXC1 Links Ensembl NCBI GeneCards UniProt	ENSG00000054598.5	FOXC1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXC1	hg19_v2_chr6_+_1610681_1610681	0.78	3.6e-04	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr10_+_54074033	3.37	ENST00000373970.3	DKK1	dickkopf WNT signaling pathway inhibitor 1
chr8_-_23261589	3.31	ENST00000524168.1 ENST00000523833.2 ENST00000519243.1 ENST00000389131.3	LOXL2	lysyl oxidase-like 2
chr5_-_39425222	3.26	ENST00000320816.6	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425290	3.17	ENST00000545653.1	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_39425068	2.54	ENST00000515700.1 ENST00000339788.6	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr10_+_71561649	2.49	ENST00000398978.3 ENST00000354547.3 ENST00000357811.3	COL13A1	collagen, type XIII, alpha 1
chr2_-_190044480	2.45	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr4_-_102267953	2.27	ENST00000523694.2 ENST00000507176.1	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr8_-_93107443	2.15	ENST00000360348.2 ENST00000520428.1 ENST00000518992.1 ENST00000520556.1 ENST00000518317.1 ENST00000521319.1 ENST00000521375.1 ENST00000518449.1	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_99578789	2.06	ENST00000511651.1 ENST00000505184.1	TSPAN5	tetraspanin 5
chr3_-_127455200	1.87	ENST00000398101.3	MGLL	monoglyceride lipase
chr10_+_71561704	1.80	ENST00000520267.1	COL13A1	collagen, type XIII, alpha 1
chr4_-_99578776	1.70	ENST00000515287.1	TSPAN5	tetraspanin 5
chr2_+_33359646	1.64	ENST00000390003.4 ENST00000418533.2	LTBP1	latent transforming growth factor beta binding protein 1
chr8_+_70404996	1.63	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr2_+_33359687	1.61	ENST00000402934.1 ENST00000404525.1 ENST00000407925.1	LTBP1	latent transforming growth factor beta binding protein 1
chr18_-_53303123	1.57	ENST00000569357.1 ENST00000565124.1 ENST00000398339.1	TCF4	transcription factor 4
chr4_-_102268484	1.55	ENST00000394853.4	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_94079648	1.48	ENST00000370247.3	BCAR3	breast cancer anti-estrogen resistance 3
chr15_-_30114622	1.44	ENST00000495972.2 ENST00000346128.6	TJP1	tight junction protein 1
chr3_-_168865522	1.37	ENST00000464456.1	MECOM	MDS1 and EVI1 complex locus
chr4_-_102268628	1.36	ENST00000323055.6 ENST00000512215.1 ENST00000394854.3	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_+_86396265	1.33	ENST00000395184.1	ARHGAP24	Rho GTPase activating protein 24
chr2_-_208030647	1.29	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr10_+_71561630	1.27	ENST00000398974.3 ENST00000398971.3 ENST00000398968.3 ENST00000398966.3 ENST00000398964.3 ENST00000398969.3 ENST00000356340.3 ENST00000398972.3 ENST00000398973.3	COL13A1	collagen, type XIII, alpha 1
chr10_+_114709999	1.23	ENST00000355995.4 ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr7_-_95064264	1.22	ENST00000536183.1 ENST00000433091.2 ENST00000222572.3	PON2	paraoxonase 2
chr15_+_96869165	1.19	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr3_-_16524357	1.18	ENST00000432519.1	RFTN1	raftlin, lipid raft linker 1
chr17_-_46688334	1.13	ENST00000239165.7	HOXB7	homeobox B7
chr8_+_31496809	1.11	ENST00000518104.1 ENST00000519301.1	NRG1	neuregulin 1
chr8_+_31497271	1.06	ENST00000520407.1	NRG1	neuregulin 1
chr1_-_100231349	1.04	ENST00000287474.5 ENST00000414213.1	FRRS1	ferric-chelate reductase 1
chr1_-_94312706	0.96	ENST00000370244.1	BCAR3	breast cancer anti-estrogen resistance 3
chr7_-_27219849	0.95	ENST00000396344.4	HOXA10	homeobox A10
chr8_+_54764346	0.95	ENST00000297313.3 ENST00000344277.6	RGS20	regulator of G-protein signaling 20
chr12_-_49333446	0.94	ENST00000537495.1	AC073610.5	Uncharacterized protein
chr12_-_10251603	0.91	ENST00000457018.2	CLEC1A	C-type lectin domain family 1, member A
chr18_-_53070913	0.91	ENST00000568186.1 ENST00000564228.1	TCF4	transcription factor 4
chr19_-_36523709	0.90	ENST00000592017.1 ENST00000360535.4	CLIP3	CAP-GLY domain containing linker protein 3
chr12_+_10365404	0.89	ENST00000266458.5 ENST00000421801.2 ENST00000544284.1 ENST00000545047.1 ENST00000543602.1 ENST00000545887.1	GABARAPL1	GABA(A) receptor-associated protein like 1
chr21_+_39628852	0.89	ENST00000398938.2	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_10251539	0.88	ENST00000420265.2	CLEC1A	C-type lectin domain family 1, member A
chr12_+_16109519	0.87	ENST00000526530.1	DERA	deoxyribose-phosphate aldolase (putative)
chr9_-_89562104	0.87	ENST00000298743.7	GAS1	growth arrest-specific 1
chr12_-_123756781	0.85	ENST00000544658.1	CDK2AP1	cyclin-dependent kinase 2 associated protein 1
chr8_-_134309823	0.82	ENST00000414097.2	NDRG1	N-myc downstream regulated 1
chr5_-_111091948	0.81	ENST00000447165.2	NREP	neuronal regeneration related protein
chr14_+_23340822	0.75	ENST00000359591.4	LRP10	low density lipoprotein receptor-related protein 10
chr18_+_19749386	0.72	ENST00000269216.3	GATA6	GATA binding protein 6
chr3_-_133969673	0.71	ENST00000427044.2	RYK	receptor-like tyrosine kinase
chr8_-_134309335	0.69	ENST00000522890.1 ENST00000323851.7 ENST00000518176.1 ENST00000354944.5 ENST00000537882.1 ENST00000522476.1 ENST00000518066.1 ENST00000521544.1 ENST00000518480.1 ENST00000523892.1	NDRG1	N-myc downstream regulated 1
chr3_-_114343039	0.69	ENST00000481632.1	ZBTB20	zinc finger and BTB domain containing 20
chr21_+_39628655	0.67	ENST00000398925.1 ENST00000398928.1 ENST00000328656.4 ENST00000443341.1	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_93107696	0.65	ENST00000436581.2 ENST00000520583.1 ENST00000519061.1	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_42016385	0.64	ENST00000502771.1 ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4	CCND3	cyclin D3
chr15_-_72563585	0.61	ENST00000287196.9 ENST00000260376.7	PARP6	poly (ADP-ribose) polymerase family, member 6
chr15_-_55657428	0.60	ENST00000568543.1	CCPG1	cell cycle progression 1
chr1_-_169703203	0.59	ENST00000333360.7 ENST00000367781.4 ENST00000367782.4 ENST00000367780.4 ENST00000367779.4	SELE	selectin E
chr8_+_120079478	0.57	ENST00000332843.2	COLEC10	collectin sub-family member 10 (C-type lectin)
chr6_-_31651817	0.55	ENST00000375863.3 ENST00000375860.2	LY6G5C	lymphocyte antigen 6 complex, locus G5C
chr2_+_210517895	0.55	ENST00000447185.1	MAP2	microtubule-associated protein 2
chr3_-_114477787	0.51	ENST00000464560.1	ZBTB20	zinc finger and BTB domain containing 20
chr3_-_114477962	0.51	ENST00000471418.1	ZBTB20	zinc finger and BTB domain containing 20
chr1_-_57045228	0.51	ENST00000371250.3	PPAP2B	phosphatidic acid phosphatase type 2B
chr10_-_118032697	0.50	ENST00000439649.3	GFRA1	GDNF family receptor alpha 1
chr22_-_38699003	0.50	ENST00000451964.1	CSNK1E	casein kinase 1, epsilon
chr6_-_152489484	0.50	ENST00000354674.4 ENST00000539504.1	SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_-_6440283	0.50	ENST00000299402.6 ENST00000609360.1 ENST00000389906.2 ENST00000532020.2	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_-_15382875	0.50	ENST00000408919.3	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr11_-_6440624	0.49	ENST00000311051.3	APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr12_+_27175476	0.48	ENST00000546323.1 ENST00000282892.3	MED21	mediator complex subunit 21
chr1_+_220701456	0.46	ENST00000366918.4 ENST00000402574.1	MARK1	MAP/microtubule affinity-regulating kinase 1
chr7_-_42951509	0.44	ENST00000438029.1 ENST00000432637.1 ENST00000447342.1 ENST00000431882.2 ENST00000350427.4 ENST00000425683.1	C7orf25	chromosome 7 open reading frame 25
chr10_-_118031778	0.41	ENST00000369236.1	GFRA1	GDNF family receptor alpha 1
chr4_+_71587669	0.39	ENST00000381006.3 ENST00000226328.4	RUFY3	RUN and FYVE domain containing 3
chr16_-_53737795	0.39	ENST00000262135.4 ENST00000564374.1 ENST00000566096.1	RPGRIP1L	RPGRIP1-like
chr15_+_67418047	0.39	ENST00000540846.2	SMAD3	SMAD family member 3
chr16_-_53737722	0.37	ENST00000569716.1 ENST00000562588.1 ENST00000562230.1 ENST00000379925.3 ENST00000563746.1 ENST00000568653.3	RPGRIP1L	RPGRIP1-like
chr3_-_49131788	0.37	ENST00000395443.2 ENST00000411682.1	QRICH1	glutamine-rich 1
chr10_-_118032979	0.37	ENST00000355422.6	GFRA1	GDNF family receptor alpha 1
chr12_+_122516626	0.37	ENST00000319080.7	MLXIP	MLX interacting protein
chr2_-_71454185	0.35	ENST00000244221.8	PAIP2B	poly(A) binding protein interacting protein 2B
chr4_-_186696425	0.34	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr7_-_14028488	0.34	ENST00000405358.4	ETV1	ets variant 1
chr6_-_152639479	0.34	ENST00000356820.4	SYNE1	spectrin repeat containing, nuclear envelope 1
chr3_+_46448648	0.33	ENST00000399036.3	CCRL2	chemokine (C-C motif) receptor-like 2
chr7_-_14029283	0.32	ENST00000433547.1 ENST00000405192.2	ETV1	ets variant 1
chr7_-_72972319	0.32	ENST00000223368.2	BCL7B	B-cell CLL/lymphoma 7B
chr19_-_4831701	0.31	ENST00000248244.5	TICAM1	toll-like receptor adaptor molecule 1
chr10_+_71562180	0.31	ENST00000517713.1 ENST00000522165.1 ENST00000520133.1	COL13A1	collagen, type XIII, alpha 1
chr1_+_43855560	0.31	ENST00000562955.1	SZT2	seizure threshold 2 homolog (mouse)
chr11_+_27076764	0.31	ENST00000525090.1	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr16_+_8715536	0.31	ENST00000563958.1 ENST00000381920.3 ENST00000564554.1	METTL22	methyltransferase like 22
chr6_+_101846664	0.30	ENST00000421544.1 ENST00000413795.1 ENST00000369138.1 ENST00000358361.3	GRIK2	glutamate receptor, ionotropic, kainate 2
chr16_+_8715574	0.29	ENST00000561758.1	METTL22	methyltransferase like 22
chr11_-_66112555	0.29	ENST00000425825.2 ENST00000359957.3	BRMS1	breast cancer metastasis suppressor 1
chr8_-_93107827	0.28	ENST00000520724.1 ENST00000518844.1	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr16_+_56969284	0.28	ENST00000568358.1	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_+_6069072	0.28	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_6069586	0.27	ENST00000547372.1	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_189349162	0.27	ENST00000264731.3 ENST00000382063.4 ENST00000418709.2 ENST00000320472.5 ENST00000392460.3 ENST00000440651.2	TP63	tumor protein p63
chr15_-_50411412	0.27	ENST00000284509.6	ATP8B4	ATPase, class I, type 8B, member 4
chr1_+_25664408	0.26	ENST00000374358.4	TMEM50A	transmembrane protein 50A
chr1_+_155099927	0.26	ENST00000368407.3	EFNA1	ephrin-A1
chr2_+_207024306	0.25	ENST00000236957.5 ENST00000392221.1 ENST00000392222.2 ENST00000445505.1	EEF1B2	eukaryotic translation elongation factor 1 beta 2
chr2_-_161056762	0.25	ENST00000428609.2 ENST00000409967.2	ITGB6	integrin, beta 6
chr4_-_164534657	0.25	ENST00000339875.5	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr3_+_46449049	0.25	ENST00000357392.4 ENST00000400880.3 ENST00000433848.1	CCRL2	chemokine (C-C motif) receptor-like 2
chrX_+_54947229	0.25	ENST00000442098.1 ENST00000430420.1 ENST00000453081.1 ENST00000173898.7 ENST00000319167.8 ENST00000375022.4 ENST00000399736.1 ENST00000440072.1 ENST00000420798.2 ENST00000431115.1 ENST00000440759.1 ENST00000375041.2	TRO	trophinin
chr2_+_173686303	0.24	ENST00000397087.3	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_44502597	0.24	ENST00000260649.6 ENST00000409387.1	SLC3A1	solute carrier family 3 (amino acid transporter heavy chain), member 1
chr7_+_79998864	0.23	ENST00000435819.1	CD36	CD36 molecule (thrombospondin receptor)
chr10_+_13652047	0.23	ENST00000601460.1	RP11-295P9.3	Uncharacterized protein
chrX_+_38211777	0.23	ENST00000039007.4	OTC	ornithine carbamoyltransferase
chr10_+_95517660	0.22	ENST00000371413.3	LGI1	leucine-rich, glioma inactivated 1
chr3_+_178866199	0.22	ENST00000263967.3	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_-_161056802	0.22	ENST00000283249.2 ENST00000409872.1	ITGB6	integrin, beta 6
chr17_+_57642886	0.21	ENST00000251241.4 ENST00000451169.2 ENST00000425628.3 ENST00000584385.1 ENST00000580030.1	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_-_19540086	0.21	ENST00000332246.6	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr4_-_83765613	0.21	ENST00000503937.1	SEC31A	SEC31 homolog A (S. cerevisiae)
chr13_+_27825706	0.21	ENST00000272274.4 ENST00000319826.4 ENST00000326092.4	RPL21	ribosomal protein L21
chr3_-_48481434	0.21	ENST00000395694.2 ENST00000447018.1 ENST00000442740.1	CCDC51	coiled-coil domain containing 51
chr3_-_128902729	0.21	ENST00000451728.2 ENST00000446936.2 ENST00000502976.1 ENST00000500450.2 ENST00000441626.2	CNBP	CCHC-type zinc finger, nucleic acid binding protein
chr3_+_48481658	0.20	ENST00000438607.2	TMA7	translation machinery associated 7 homolog (S. cerevisiae)
chr3_+_171758344	0.20	ENST00000336824.4 ENST00000423424.1	FNDC3B	fibronectin type III domain containing 3B
chr16_-_4817129	0.19	ENST00000545009.1 ENST00000219478.6	ZNF500	zinc finger protein 500
chr4_-_74486347	0.19	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr1_-_246729544	0.18	ENST00000544618.1 ENST00000366514.4	TFB2M	transcription factor B2, mitochondrial
chr1_+_73771844	0.18	ENST00000440762.1 ENST00000444827.1 ENST00000415686.1 ENST00000411903.1	RP4-598G3.1	RP4-598G3.1
chr13_+_27825446	0.18	ENST00000311549.6	RPL21	ribosomal protein L21
chr15_+_58430567	0.18	ENST00000536493.1	AQP9	aquaporin 9
chr3_-_48481518	0.17	ENST00000412398.2 ENST00000395696.1	CCDC51	coiled-coil domain containing 51
chr22_-_43036607	0.17	ENST00000505920.1	ATP5L2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr1_+_18958008	0.16	ENST00000420770.2 ENST00000400661.3	PAX7	paired box 7
chr2_+_181845843	0.16	ENST00000602710.1	UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr8_-_141931287	0.16	ENST00000517887.1	PTK2	protein tyrosine kinase 2
chr5_+_179921344	0.15	ENST00000261951.4	CNOT6	CCR4-NOT transcription complex, subunit 6
chr19_-_52255107	0.15	ENST00000595042.1 ENST00000304748.4	FPR1	formyl peptide receptor 1
chr17_-_19290483	0.15	ENST00000395592.2 ENST00000299610.4	MFAP4	microfibrillar-associated protein 4
chr15_+_80351977	0.15	ENST00000559157.1 ENST00000561012.1 ENST00000564367.1 ENST00000558494.1	ZFAND6	zinc finger, AN1-type domain 6
chr7_+_80231466	0.15	ENST00000309881.7 ENST00000534394.1	CD36	CD36 molecule (thrombospondin receptor)
chr6_-_52926539	0.14	ENST00000350082.5 ENST00000356971.3	ICK	intestinal cell (MAK-like) kinase
chr5_+_179921430	0.13	ENST00000393356.1	CNOT6	CCR4-NOT transcription complex, subunit 6
chr20_-_35890211	0.12	ENST00000373614.2	GHRH	growth hormone releasing hormone
chr19_+_36024310	0.11	ENST00000222286.4	GAPDHS	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr20_-_17511962	0.11	ENST00000377873.3	BFSP1	beaded filament structural protein 1, filensin
chr12_+_54378923	0.11	ENST00000303460.4	HOXC10	homeobox C10
chr2_-_152146385	0.10	ENST00000414946.1 ENST00000243346.5	NMI	N-myc (and STAT) interactor
chr12_-_92539614	0.10	ENST00000256015.3	BTG1	B-cell translocation gene 1, anti-proliferative
chr2_-_224467093	0.10	ENST00000305409.2	SCG2	secretogranin II
chrX_-_138790348	0.10	ENST00000414978.1 ENST00000519895.1	MCF2	MCF.2 cell line derived transforming sequence
chr14_-_92572894	0.09	ENST00000532032.1 ENST00000506466.1 ENST00000555381.1 ENST00000557311.1 ENST00000554592.1 ENST00000554672.1 ENST00000553491.1 ENST00000556220.1 ENST00000502250.1 ENST00000503767.1 ENST00000393287.5 ENST00000340660.6 ENST00000545170.1 ENST00000429774.2	ATXN3	ataxin 3
chr1_-_43855444	0.09	ENST00000372455.4	MED8	mediator complex subunit 8
chr5_-_146302078	0.09	ENST00000508545.2	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr2_-_27886676	0.09	ENST00000337768.5	SUPT7L	suppressor of Ty 7 (S. cerevisiae)-like
chr9_+_71944241	0.09	ENST00000257515.8	FAM189A2	family with sequence similarity 189, member A2
chr12_+_99038919	0.08	ENST00000551964.1	APAF1	apoptotic peptidase activating factor 1
chr11_-_790060	0.08	ENST00000330106.4	CEND1	cell cycle exit and neuronal differentiation 1
chr13_+_52598827	0.07	ENST00000521776.2	UTP14C	UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr22_+_41487711	0.07	ENST00000263253.7	EP300	E1A binding protein p300
chr15_+_58430368	0.06	ENST00000558772.1 ENST00000219919.4	AQP9	aquaporin 9
chr1_-_159684371	0.06	ENST00000255030.5 ENST00000437342.1 ENST00000368112.1 ENST00000368111.1 ENST00000368110.1 ENST00000343919.2	CRP	C-reactive protein, pentraxin-related
chr1_-_19811132	0.06	ENST00000433834.1	CAPZB	capping protein (actin filament) muscle Z-line, beta
chr20_+_36946029	0.06	ENST00000417318.1	BPI	bactericidal/permeability-increasing protein
chr10_+_95517616	0.05	ENST00000371418.4	LGI1	leucine-rich, glioma inactivated 1
chr17_+_7533439	0.04	ENST00000441599.2 ENST00000380450.4 ENST00000416273.3 ENST00000575903.1 ENST00000576830.1 ENST00000571153.1 ENST00000575618.1 ENST00000576152.1	SHBG	sex hormone-binding globulin
chr1_-_149982624	0.04	ENST00000417191.1 ENST00000369135.4	OTUD7B	OTU domain containing 7B
chr6_+_45296391	0.03	ENST00000371436.6 ENST00000576263.1	RUNX2	runt-related transcription factor 2
chr13_-_36050819	0.03	ENST00000379919.4	MAB21L1	mab-21-like 1 (C. elegans)
chr20_+_44509857	0.03	ENST00000372523.1 ENST00000372520.1	ZSWIM1	zinc finger, SWIM-type containing 1
chr11_-_108464321	0.03	ENST00000265843.4	EXPH5	exophilin 5
chr1_-_116383738	0.02	ENST00000320238.3	NHLH2	nescient helix loop helix 2
chr9_-_5185629	0.02	ENST00000381641.3	INSL6	insulin-like 6
chr15_+_80351910	0.02	ENST00000261749.6 ENST00000561060.1	ZFAND6	zinc finger, AN1-type domain 6
chr10_+_95517566	0.02	ENST00000542308.1	LGI1	leucine-rich, glioma inactivated 1
chr18_+_21032781	0.01	ENST00000339486.3	RIOK3	RIO kinase 3
chr3_-_11623804	0.01	ENST00000451674.2	VGLL4	vestigial like 4 (Drosophila)
chr11_+_8040739	0.01	ENST00000534099.1	TUB	tubby bipartite transcription factor
chr1_-_150669500	0.01	ENST00000271732.3	GOLPH3L	golgi phosphoprotein 3-like
chr11_-_108464465	0.00	ENST00000525344.1	EXPH5	exophilin 5
chr2_-_8977714	0.00	ENST00000319688.5 ENST00000489024.1 ENST00000256707.3 ENST00000427284.1 ENST00000418530.1 ENST00000473731.1	KIDINS220	kinase D-interacting substrate, 220kDa
chr11_+_112832090	0.00	ENST00000533760.1	NCAM1	neural cell adhesion molecule 1
chr3_-_195310802	0.00	ENST00000421243.1 ENST00000453131.1	APOD	apolipoprotein D

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.3	GO:0050436	microfibril binding(GO:0050436)
0.6	3.9	GO:0070492	oligosaccharide binding(GO:0070492)
0.5	5.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.4	1.6	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4	9.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4	1.2	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3	3.4	GO:0039706	co-receptor binding(GO:0039706)
0.3	0.9	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.2	0.9	GO:0097001	ceramide binding(GO:0097001)
0.2	2.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	2.5	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.3	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2	1.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	1.9	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.7	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1	0.7	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	1.6	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.4	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.3	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	0.2	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.1	0.9	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.4	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.1	1.0	GO:0048156	tau protein binding(GO:0048156)
0.0	1.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.2	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0005124	scavenger receptor binding(GO:0005124)
0.0	0.6	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0	2.0	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.8	GO:0005521	lamin binding(GO:0005521)
0.0	5.9	GO:0008201	heparin binding(GO:0008201)
0.0	0.6	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.9	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	2.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.5	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.7	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0033265	choline binding(GO:0033265)
0.0	1.2	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	1.2	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	5.9	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.0	9.0	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8	2.5	GO:0005588	collagen type V trimer(GO:0005588)
0.6	5.2	GO:0005955	calcineurin complex(GO:0005955)
0.3	0.8	GO:0005879	axonemal microtubule(GO:0005879)
0.2	0.5	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.2	3.3	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	1.0	GO:1990812	growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1	0.6	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.1	0.5	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	2.2	GO:0030673	axolemma(GO:0030673)
0.1	0.8	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:1990130	Iml1 complex(GO:1990130)
0.0	1.4	GO:0005921	gap junction(GO:0005921)
0.0	0.4	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	0.3	GO:1990037	Lewy body core(GO:1990037)
0.0	0.2	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0	1.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	1.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	2.3	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	3.2	GO:0005604	basement membrane(GO:0005604)
0.0	3.6	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	3.1	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.3	GO:0097342	ripoptosome(GO:0097342)
0.0	0.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.6	GO:0016592	mediator complex(GO:0016592)
0.0	0.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	2.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.3	NABA COLLAGENS	Genes encoding collagen proteins
0.1	4.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	9.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	4.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	1.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	3.1	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	4.6	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.7	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	3.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.5	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.0	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	8.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	5.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	1.4	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	2.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	2.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	1.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	1.8	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	9.0	GO:0035026	leading edge cell differentiation(GO:0035026)
1.7	5.2	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
1.5	5.8	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.5	1.4	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4	3.2	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3	1.0	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3	2.2	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3	1.2	GO:0009956	radial pattern formation(GO:0009956)
0.3	1.9	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.3	2.9	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2	0.7	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2	0.9	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	0.7	GO:0036518	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.2	1.2	GO:0032594	protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.1	0.9	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	1.5	GO:0090232	peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.1	3.7	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	0.6	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	5.8	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.6	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.4	GO:0006109	regulation of carbohydrate metabolic process(GO:0006109)
0.1	0.3	GO:0003180	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.1	0.8	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	3.8	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	1.9	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.1	0.2	GO:0070781	arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1	0.2	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	1.1	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.4	GO:2000334	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1	0.9	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	1.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.9	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
0.0	0.5	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.0	0.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	1.1	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	1.4	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.2	GO:1990822	L-cystine transport(GO:0015811) basic amino acid transmembrane transport(GO:1990822)
0.0	0.3	GO:0045350	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of chemokine biosynthetic process(GO:0045080) interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	1.6	GO:0010107	potassium ion import(GO:0010107)
0.0	1.0	GO:0060065	uterus development(GO:0060065)
0.0	0.1	GO:0035720	intraciliary anterograde transport(GO:0035720)
0.0	0.5	GO:2000052	positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.7	GO:0048934	mechanosensory behavior(GO:0007638) peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.3	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	1.3	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	1.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.3	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0	0.3	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.5	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.1	GO:0021590	cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.3	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)