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ENCODE cell lines, expression (Ernst 2011)

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Results for FOXD3_FOXI1_FOXF1

Z-value: 1.33

Motif logo

Transcription factors associated with FOXD3_FOXI1_FOXF1

Gene Symbol Gene ID Gene Info
ENSG00000187140.4 FOXD3
ENSG00000168269.7 FOXI1
ENSG00000103241.5 FOXF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXF1hg19_v2_chr16_+_86544113_865441450.292.7e-01Click!
FOXD3hg19_v2_chr1_+_63788730_63788730-0.224.2e-01Click!
FOXI1hg19_v2_chr5_+_169532896_1695329170.039.1e-01Click!

Activity profile of FOXD3_FOXI1_FOXF1 motif

Sorted Z-values of FOXD3_FOXI1_FOXF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD3_FOXI1_FOXF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_111091948 3.14 ENST00000447165.2
NREP
neuronal regeneration related protein
chr3_-_16524357 3.04 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr18_-_53070913 2.76 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr13_-_47012325 2.57 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr4_-_84035868 2.48 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr4_+_68424434 2.38 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr2_-_152146385 2.37 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr4_-_84035905 2.33 ENST00000311507.4
PLAC8
placenta-specific 8
chr5_-_88179302 2.32 ENST00000504921.2
MEF2C
myocyte enhancer factor 2C
chr2_-_158345462 2.09 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr17_-_29641104 1.76 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr1_+_150122034 1.75 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr4_-_105416039 1.66 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_-_29641084 1.65 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr10_-_98031265 1.57 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr6_-_133084580 1.53 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr10_-_98031310 1.53 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr12_+_59989791 1.42 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr20_+_9494987 1.40 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr3_-_121379739 1.38 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_173174681 1.33 ENST00000367718.1
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_108510224 1.31 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr15_+_89181974 1.30 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 1.27 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_-_27952741 1.25 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr15_+_89182178 1.24 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr5_-_54281407 1.24 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr1_+_111415757 1.23 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr7_+_119913688 1.21 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr10_-_14050522 1.20 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr8_+_79428539 1.20 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr12_-_15038779 1.19 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr17_-_46688334 1.16 ENST00000239165.7
HOXB7
homeobox B7
chr18_-_53253323 1.13 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr6_+_114178512 1.13 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_-_120685608 1.11 ENST00000427067.2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_+_127413677 1.10 ENST00000356887.7
GYPC
glycophorin C (Gerbich blood group)
chr18_-_53253112 1.10 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr7_-_144435985 1.07 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr12_-_49333446 1.04 ENST00000537495.1
AC073610.5
Uncharacterized protein
chr1_+_174844645 1.03 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_-_127455200 1.00 ENST00000398101.3
MGLL
monoglyceride lipase
chrX_+_9431324 0.99 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr3_-_119278376 0.98 ENST00000478182.1
CD80
CD80 molecule
chr18_-_53089723 0.98 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr10_-_90712520 0.97 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_+_35484793 0.96 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr12_-_92539614 0.96 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_+_32739733 0.96 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr2_+_33661382 0.95 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_89790490 0.94 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_192544857 0.93 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chrX_+_24483338 0.92 ENST00000379162.4
ENST00000441463.2
PDK3
pyruvate dehydrogenase kinase, isozyme 3
chrX_-_70331298 0.91 ENST00000456850.2
ENST00000473378.1
ENST00000487883.1
ENST00000374202.2
IL2RG
interleukin 2 receptor, gamma
chr18_-_53177984 0.90 ENST00000543082.1
TCF4
transcription factor 4
chr7_-_37026108 0.88 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr3_+_119316689 0.88 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr6_+_31582961 0.87 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr6_-_131291572 0.87 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr8_-_120651020 0.86 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr21_-_15918618 0.85 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr3_-_119278446 0.85 ENST00000264246.3
CD80
CD80 molecule
chr2_-_175711133 0.84 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr7_-_144533074 0.84 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr16_-_24942655 0.84 ENST00000573765.1
ARHGAP17
Rho GTPase activating protein 17
chr14_-_25479811 0.83 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr5_-_111093167 0.83 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr13_-_46756351 0.82 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_152639479 0.81 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_19811132 0.81 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr1_-_160681593 0.80 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chrX_-_154563889 0.77 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr6_-_26056695 0.77 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr13_-_46716969 0.77 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_-_24942273 0.77 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr1_-_57045228 0.76 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr17_+_67498538 0.76 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr15_-_55562582 0.76 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr11_-_73693875 0.75 ENST00000536983.1
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_-_46922659 0.75 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr3_-_119276575 0.74 ENST00000383669.3
ENST00000383668.3
CD80
CD80 molecule
chr15_-_37390482 0.74 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr13_-_99959641 0.73 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr3_+_119316721 0.73 ENST00000488919.1
ENST00000495992.1
PLA1A
phospholipase A1 member A
chrX_-_70329118 0.72 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr3_+_178276488 0.72 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_+_12958137 0.72 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr1_-_150669500 0.72 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr11_-_78052923 0.72 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr5_+_156712372 0.72 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_114035026 0.71 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr13_+_50070077 0.71 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr18_+_77160282 0.70 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr14_+_61654271 0.69 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr10_+_31610064 0.69 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr12_+_48513009 0.67 ENST00000359794.5
ENST00000551339.1
ENST00000395233.2
ENST00000548345.1
PFKM
phosphofructokinase, muscle
chr14_-_23285011 0.66 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_116654935 0.66 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr11_-_93276582 0.65 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr4_-_38806404 0.65 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
TLR1
toll-like receptor 1
chr1_-_92371839 0.64 ENST00000370399.2
TGFBR3
transforming growth factor, beta receptor III
chr11_+_93479588 0.64 ENST00000526335.1
C11orf54
chromosome 11 open reading frame 54
chr6_-_152489484 0.63 ENST00000354674.4
ENST00000539504.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr12_-_91576561 0.63 ENST00000547568.2
ENST00000552962.1
DCN
decorin
chr11_-_46142948 0.63 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr17_-_19290483 0.62 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr12_-_9913489 0.62 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr3_-_127541194 0.62 ENST00000453507.2
MGLL
monoglyceride lipase
chr6_+_32812568 0.61 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr22_-_17680472 0.61 ENST00000330232.4
CECR1
cat eye syndrome chromosome region, candidate 1
chr7_-_86849025 0.61 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr6_+_89790459 0.61 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr18_-_53069419 0.61 ENST00000570177.2
TCF4
transcription factor 4
chr3_-_114343039 0.60 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_94417339 0.60 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr11_+_65657875 0.60 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr13_-_99910673 0.60 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr7_-_37488834 0.59 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr14_-_23285069 0.59 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_92414055 0.59 ENST00000342058.4
FBLN5
fibulin 5
chr4_-_103266626 0.59 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_-_23288930 0.58 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr18_-_53303123 0.58 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr2_+_152214098 0.57 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_+_59989918 0.57 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_+_10365404 0.56 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr2_+_58655461 0.56 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr8_+_70404996 0.55 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr10_-_46030841 0.55 ENST00000453424.2
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr11_+_5710919 0.55 ENST00000379965.3
ENST00000425490.1
TRIM22
tripartite motif containing 22
chr1_+_66797687 0.54 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_198608146 0.54 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr3_+_157154578 0.54 ENST00000295927.3
PTX3
pentraxin 3, long
chr9_-_16727978 0.53 ENST00000418777.1
ENST00000468187.2
BNC2
basonuclin 2
chr1_-_170043709 0.53 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3
kinesin-associated protein 3
chr3_+_152017360 0.53 ENST00000485910.1
ENST00000463374.1
MBNL1
muscleblind-like splicing regulator 1
chr15_-_55562479 0.52 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr12_-_68696652 0.52 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr8_+_74903580 0.51 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr19_-_11689752 0.50 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr7_+_142985308 0.49 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr2_-_191878162 0.49 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_-_105588231 0.48 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr11_-_72070206 0.48 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr4_+_184365744 0.48 ENST00000504169.1
ENST00000302350.4
CDKN2AIP
CDKN2A interacting protein
chr10_-_94003003 0.48 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr7_+_120590803 0.47 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr11_-_62323702 0.47 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr15_-_55563072 0.47 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr7_+_28452130 0.47 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr9_+_2029019 0.47 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_26321284 0.47 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr6_-_16761678 0.46 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr1_-_32801825 0.46 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr12_-_15114492 0.46 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_207095324 0.45 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr12_-_15114603 0.45 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr5_+_68665608 0.45 ENST00000509734.1
ENST00000354868.5
ENST00000521422.1
ENST00000354312.3
ENST00000345306.6
RAD17
RAD17 homolog (S. pombe)
chr5_-_142782862 0.44 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_201994569 0.44 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr18_+_32556892 0.44 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_164528866 0.43 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_17578815 0.43 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr12_-_91576429 0.43 ENST00000552145.1
ENST00000546745.1
DCN
decorin
chr12_+_54892550 0.43 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr7_+_80231466 0.42 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr14_+_65878565 0.42 ENST00000556518.1
ENST00000557164.1
FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr12_+_12878829 0.42 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr11_+_128563948 0.42 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_89378261 0.42 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr8_-_95449155 0.42 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr9_-_20622478 0.41 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_+_2015335 0.41 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_226411319 0.40 ENST00000542034.1
ENST00000366810.5
MIXL1
Mix paired-like homeobox
chr1_-_226926864 0.40 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr17_-_37934466 0.40 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr4_+_146403912 0.40 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr3_+_141106643 0.39 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr20_-_5093399 0.39 ENST00000379276.4
TMEM230
transmembrane protein 230
chr2_-_231989808 0.39 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr11_-_108093329 0.39 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr20_-_5093673 0.39 ENST00000379299.2
ENST00000379286.2
ENST00000379279.2
ENST00000379283.2
TMEM230
transmembrane protein 230
chr12_-_91574142 0.38 ENST00000547937.1
DCN
decorin
chr6_-_112575912 0.37 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr20_-_5093503 0.37 ENST00000379277.2
TMEM230
transmembrane protein 230
chr20_-_5093713 0.37 ENST00000342308.5
ENST00000202834.7
TMEM230
transmembrane protein 230
chr13_+_76334567 0.37 ENST00000321797.8
LMO7
LIM domain 7
chr3_+_69812877 0.37 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr21_+_30502806 0.37 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr13_+_76334795 0.37 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr11_+_63304273 0.36 ENST00000439013.2
ENST00000255688.3
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr11_+_128563652 0.36 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_120591170 0.36 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr8_-_60031762 0.36 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr15_+_80351910 0.36 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr6_-_41703952 0.35 ENST00000358871.2
ENST00000403298.4
TFEB
transcription factor EB
chr5_-_24645078 0.35 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr16_+_27438563 0.35 ENST00000395754.4
IL21R
interleukin 21 receptor
chr3_-_49066811 0.35 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr11_-_790060 0.35 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 8.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 ST ADRENERGIC Adrenergic Pathway
0.0 1.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 8.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 2.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 1.6 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.5 1.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.5 2.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 2.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 0.8 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 1.9 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 0.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 2.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 0.8 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 2.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.7 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.9 GO:0042731 PH domain binding(GO:0042731)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.8 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0005497 androgen binding(GO:0005497)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 5.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 3.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.0 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 3.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 2.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.5 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 2.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.8 2.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.6 2.6 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.5 1.9 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 1.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 3.0 GO:0032596 protein transport within lipid bilayer(GO:0032594) protein transport into membrane raft(GO:0032596)
0.4 2.6 GO:0045425 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 2.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.6 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.3 1.8 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.3 1.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 1.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.3 2.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.3 1.7 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 0.8 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.3 4.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.7 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.2 1.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.1 GO:0060938 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.2 0.9 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.7 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 0.6 GO:0035690 cellular response to drug(GO:0035690)
0.2 1.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 0.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.4 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.2 1.2 GO:0071724 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.0 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.2 0.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 0.5 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.2 0.5 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 0.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 1.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 1.8 GO:0051451 myoblast migration(GO:0051451)
0.1 2.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.9 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 2.0 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.9 GO:0071672 cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317) negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.1 1.8 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.5 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1 1.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 1.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:0048539 immunoglobulin biosynthetic process(GO:0002378) negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) bone marrow development(GO:0048539)
0.1 0.5 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.3 GO:1904884 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.1 0.3 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0090135 actin filament branching(GO:0090135)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.3 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.2 GO:0060769 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.1 0.2 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.6 GO:0060685 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.7 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.6 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.3 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.4 GO:0045927 positive regulation of growth(GO:0045927)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.8 GO:0050900 leukocyte migration(GO:0050900)
0.1 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.9 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.3 GO:0002634 regulation of germinal center formation(GO:0002634)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.2 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.1 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.5 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.4 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 1.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.2 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.7 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.2 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0060947 cardiac vascular smooth muscle cell differentiation(GO:0060947)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.0 GO:1903044 protein localization to membrane raft(GO:1903044)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.0 8.5 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0055001 muscle cell development(GO:0055001)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.6 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0051315 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 2.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0050955 thermoception(GO:0050955) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.0 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.6 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.3 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.2 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.2 GO:0097296 positive regulation of hair follicle development(GO:0051798) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 1.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125) dUMP metabolic process(GO:0046078)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.2 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.6 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0044362 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 1.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.0 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0060312 regulation of blood vessel remodeling(GO:0060312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 0.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 2.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.4 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.8 GO:0001652 granular component(GO:0001652)
0.1 1.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.1 2.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.2 GO:0071953 elastic fiber(GO:0071953)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.2 GO:0043073 germ cell nucleus(GO:0043073)
0.1 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 5.3 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 1.5 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 2.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 3.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.9 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 2.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.2 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.5 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.1 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) endosome lumen(GO:0031904)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)