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ENCODE cell lines, expression (Ernst 2011)

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Results for FOXF2_FOXJ1

Z-value: 0.92

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Transcription factors associated with FOXF2_FOXJ1

Gene Symbol Gene ID Gene Info
FOXF2
ENSG00000137273.3 FOXF2
FOXJ1
ENSG00000129654.7 FOXJ1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXJ1hg19_v2_chr17_-_74137374_741373850.523.8e-02Click!
FOXF2hg19_v2_chr6_+_1389989_1390069-0.039.2e-01Click!

Activity profile of FOXF2_FOXJ1 motif

Sorted Z-values of FOXF2_FOXJ1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXF2_FOXJ1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_161193349 7.24 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
 APOA2
 apolipoprotein A-II
chr17_+_72426891 4.09 ENST00000392627.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr4_+_100495864 3.76 ENST00000265517.5
ENST00000422897.2
 MTTP
 microsomal triglyceride transfer protein
chr5_-_42812143 3.49 ENST00000514985.1
 SEPP1
 selenoprotein P, plasma, 1
chr17_+_72427477 3.39 ENST00000342648.5
ENST00000481232.1
 GPRC5C
 G protein-coupled receptor, family C, group 5, member C
chr5_-_42811986 3.31 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
 SEPP1
 selenoprotein P, plasma, 1
chr2_+_128175997 2.98 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
 PROC
 protein C (inactivator of coagulation factors Va and VIIIa)
chr17_-_7082668 2.85 ENST00000573083.1
ENST00000574388.1
 ASGR1
 asialoglycoprotein receptor 1
chr11_-_115375107 2.59 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chr19_+_18496957 2.13 ENST00000252809.3
 GDF15
 growth differentiation factor 15
chr20_-_22566089 1.86 ENST00000377115.4
 FOXA2
 forkhead box A2
chr2_+_58655461 1.69 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
 AC007092.1
 long intergenic non-protein coding RNA 1122
chr13_-_41240717 1.51 ENST00000379561.5
 FOXO1
 forkhead box O1
chr12_-_53343602 1.38 ENST00000546897.1
ENST00000552551.1
 KRT8
 keratin 8
chr4_-_70080449 1.26 ENST00000446444.1
 UGT2B11
 UDP glucuronosyltransferase 2 family, polypeptide B11
chr8_-_134309823 1.15 ENST00000414097.2
 NDRG1
 N-myc downstream regulated 1
chr20_-_62582475 1.14 ENST00000369908.5
 UCKL1
 uridine-cytidine kinase 1-like 1
chr8_+_97597148 1.12 ENST00000521590.1
 SDC2
 syndecan 2
chr8_-_134309335 1.09 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
 NDRG1
 N-myc downstream regulated 1
chr2_+_86947296 1.04 ENST00000283632.4
 RMND5A
 required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chrX_+_9431324 1.02 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr1_+_214161854 0.99 ENST00000435016.1
 PROX1
 prospero homeobox 1
chr12_-_63328817 0.97 ENST00000228705.6
 PPM1H
 protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_-_24469602 0.87 ENST00000270800.1
 IL22RA1
 interleukin 22 receptor, alpha 1
chr1_-_57431679 0.87 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
 C8B
 complement component 8, beta polypeptide
chr20_+_44035847 0.85 ENST00000372712.2
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_140223670 0.80 ENST00000394228.1
ENST00000539387.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr20_+_44035200 0.78 ENST00000372717.1
ENST00000360981.4
 DBNDD2
 dysbindin (dystrobrevin binding protein 1) domain containing 2
chr10_-_73848086 0.77 ENST00000536168.1
 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr6_-_131321863 0.75 ENST00000528282.1
 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
chr12_-_71551652 0.75 ENST00000546561.1
 TSPAN8
 tetraspanin 8
chr5_+_156712372 0.73 ENST00000541131.1
 CYFIP2
 cytoplasmic FMR1 interacting protein 2
chr3_-_58523010 0.70 ENST00000459701.2
ENST00000302819.5
 ACOX2
 acyl-CoA oxidase 2, branched chain
chr15_-_34610962 0.70 ENST00000290209.5
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr12_-_96390063 0.68 ENST00000541929.1
 HAL
 histidine ammonia-lyase
chr18_-_52626622 0.67 ENST00000591504.1
 CCDC68
 coiled-coil domain containing 68
chr10_+_111985713 0.67 ENST00000239007.7
 MXI1
 MAX interactor 1, dimerization protein
chr3_+_98451532 0.65 ENST00000486334.2
ENST00000394162.1
 ST3GAL6
 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr3_-_185826855 0.62 ENST00000306376.5
 ETV5
 ets variant 5
chr11_-_67374177 0.61 ENST00000333139.3
 C11orf72
 chromosome 11 open reading frame 72
chr4_-_140223614 0.60 ENST00000394223.1
 NDUFC1
 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr1_+_73771844 0.56 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
 RP4-598G3.1
 RP4-598G3.1
chr15_-_34629922 0.55 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr12_+_6603253 0.54 ENST00000382457.4
ENST00000545962.1
 NCAPD2
 non-SMC condensin I complex, subunit D2
chr17_+_67410832 0.53 ENST00000590474.1
 MAP2K6
 mitogen-activated protein kinase kinase 6
chr7_-_140624499 0.52 ENST00000288602.6
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chr20_-_44993012 0.52 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
 SLC35C2
 solute carrier family 35 (GDP-fucose transporter), member C2
chr12_-_772901 0.51 ENST00000305108.4
 NINJ2
 ninjurin 2
chr2_+_33661382 0.49 ENST00000402538.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_96390108 0.48 ENST00000538703.1
ENST00000261208.3
 HAL
 histidine ammonia-lyase
chr6_+_114178512 0.48 ENST00000368635.4
 MARCKS
 myristoylated alanine-rich protein kinase C substrate
chr7_+_134832808 0.47 ENST00000275767.3
 TMEM140
 transmembrane protein 140
chr16_+_77233294 0.47 ENST00000378644.4
 SYCE1L
 synaptonemal complex central element protein 1-like
chr15_-_34630234 0.46 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_175260368 0.46 ENST00000342016.3
ENST00000362053.5
 CIR1
 corepressor interacting with RBPJ, 1
chr2_-_165424973 0.45 ENST00000543549.1
 GRB14
 growth factor receptor-bound protein 14
chr7_+_1127723 0.44 ENST00000397088.3
 GPER1
 G protein-coupled estrogen receptor 1
chr14_-_74551096 0.42 ENST00000350259.4
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr1_+_192544857 0.41 ENST00000367459.3
ENST00000469578.2
 RGS1
 regulator of G-protein signaling 1
chr12_-_71551868 0.40 ENST00000247829.3
 TSPAN8
 tetraspanin 8
chr19_+_41768561 0.40 ENST00000599719.1
ENST00000601309.1
 HNRNPUL1
 heterogeneous nuclear ribonucleoprotein U-like 1
chr2_-_27579842 0.39 ENST00000423998.1
ENST00000264720.3
 GTF3C2
 general transcription factor IIIC, polypeptide 2, beta 110kDa
chr3_-_10547333 0.39 ENST00000383800.4
 ATP2B2
 ATPase, Ca++ transporting, plasma membrane 2
chr20_+_45338126 0.37 ENST00000359271.2
 SLC2A10
 solute carrier family 2 (facilitated glucose transporter), member 10
chr2_-_157198860 0.37 ENST00000409572.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr11_-_46615498 0.36 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
 AMBRA1
 autophagy/beclin-1 regulator 1
chr4_+_79567314 0.36 ENST00000503539.1
ENST00000504675.1
 RP11-792D21.2
 long intergenic non-protein coding RNA 1094
chr2_+_220042933 0.36 ENST00000430297.2
 FAM134A
 family with sequence similarity 134, member A
chr14_-_74551172 0.36 ENST00000553458.1
 ALDH6A1
 aldehyde dehydrogenase 6 family, member A1
chr15_-_72978490 0.35 ENST00000311755.3
 HIGD2B
 HIG1 hypoxia inducible domain family, member 2B
chr6_-_76203345 0.33 ENST00000393004.2
 FILIP1
 filamin A interacting protein 1
chr7_+_119913688 0.33 ENST00000331113.4
 KCND2
 potassium voltage-gated channel, Shal-related subfamily, member 2
chr5_-_131132658 0.32 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
 CTC-432M15.3
FNIP1
 Folliculin-interacting protein 1
folliculin interacting protein 1
chr17_+_58677539 0.31 ENST00000305921.3
 PPM1D
 protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr7_+_44646177 0.29 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr1_+_87797351 0.29 ENST00000370542.1
 LMO4
 LIM domain only 4
chr6_-_43027105 0.29 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
 MRPL2
 mitochondrial ribosomal protein L2
chr7_+_73242490 0.26 ENST00000431918.1
 CLDN4
 claudin 4
chr4_+_68424434 0.26 ENST00000265404.2
ENST00000396225.1
 STAP1
 signal transducing adaptor family member 1
chr3_+_157828152 0.25 ENST00000476899.1
 RSRC1
 arginine/serine-rich coiled-coil 1
chr6_-_25830785 0.25 ENST00000468082.1
 SLC17A1
 solute carrier family 17 (organic anion transporter), member 1
chr17_-_37934466 0.24 ENST00000583368.1
 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
chr5_-_180076613 0.24 ENST00000261937.6
ENST00000393347.3
 FLT4
 fms-related tyrosine kinase 4
chr14_-_21493123 0.24 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
 NDRG2
 NDRG family member 2
chr3_-_48956818 0.23 ENST00000408959.2
 ARIH2OS
 ariadne homolog 2 opposite strand
chr21_+_34602377 0.22 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
 IFNAR2
 interferon (alpha, beta and omega) receptor 2
chr11_+_108535849 0.22 ENST00000526794.1
 DDX10
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr16_-_86542455 0.22 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
 FENDRR
 FOXF1 adjacent non-coding developmental regulatory RNA
chr1_-_152332480 0.21 ENST00000388718.5
 FLG2
 filaggrin family member 2
chr12_-_12837423 0.21 ENST00000540510.1
 GPR19
 G protein-coupled receptor 19
chr14_+_23299088 0.20 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
 MRPL52
 mitochondrial ribosomal protein L52
chr11_+_120973375 0.20 ENST00000264037.2
 TECTA
 tectorin alpha
chr6_+_32121908 0.20 ENST00000375143.2
ENST00000424499.1
 PPT2
 palmitoyl-protein thioesterase 2
chr12_-_58240470 0.20 ENST00000548823.1
ENST00000398073.2
 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr7_+_5229904 0.19 ENST00000382384.2
 WIPI2
 WD repeat domain, phosphoinositide interacting 2
chr1_+_81771806 0.19 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr16_+_28763108 0.18 ENST00000357796.3
ENST00000550983.1
 NPIPB9
 nuclear pore complex interacting protein family, member B9
chr19_-_10446449 0.18 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr13_-_99910673 0.18 ENST00000397473.2
ENST00000397470.2
 GPR18
 G protein-coupled receptor 18
chr12_-_102591604 0.18 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr15_-_40600026 0.18 ENST00000456256.2
ENST00000557821.1
 PLCB2
 phospholipase C, beta 2
chr2_-_25564750 0.18 ENST00000321117.5
 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_-_28503693 0.17 ENST00000373857.3
 PTAFR
 platelet-activating factor receptor
chr21_+_34602200 0.17 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
 IFNAR2
 interferon (alpha, beta and omega) receptor 2
chr2_+_162272605 0.17 ENST00000389554.3
 TBR1
 T-box, brain, 1
chr20_-_43150601 0.17 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
 SERINC3
 serine incorporator 3
chr8_+_38243821 0.17 ENST00000519476.2
 LETM2
 leucine zipper-EF-hand containing transmembrane protein 2
chr16_-_28374829 0.17 ENST00000532254.1
 NPIPB6
 nuclear pore complex interacting protein family, member B6
chr4_+_158142750 0.17 ENST00000505888.1
ENST00000449365.1
 GRIA2
 glutamate receptor, ionotropic, AMPA 2
chr14_+_56127989 0.17 ENST00000555573.1
 KTN1
 kinectin 1 (kinesin receptor)
chr2_-_220264703 0.16 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
 DNPEP
 aspartyl aminopeptidase
chr12_-_56352368 0.16 ENST00000549404.1
 PMEL
 premelanosome protein
chr5_+_176853669 0.16 ENST00000355472.5
 GRK6
 G protein-coupled receptor kinase 6
chr13_+_41885341 0.16 ENST00000379406.3
ENST00000379367.3
ENST00000403412.3
 NAA16
 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr6_+_32121789 0.15 ENST00000437001.2
ENST00000375137.2
 PPT2
 palmitoyl-protein thioesterase 2
chr1_+_74701062 0.15 ENST00000326637.3
 TNNI3K
 TNNI3 interacting kinase
chr20_+_52105495 0.15 ENST00000439873.2
 AL354993.1
 Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr3_-_10547192 0.15 ENST00000360273.2
ENST00000343816.4
 ATP2B2
 ATPase, Ca++ transporting, plasma membrane 2
chr2_+_61404624 0.15 ENST00000394457.3
 AHSA2
 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
chr8_+_11666649 0.14 ENST00000528643.1
ENST00000525777.1
 FDFT1
 farnesyl-diphosphate farnesyltransferase 1
chr3_+_171561127 0.14 ENST00000334567.5
ENST00000450693.1
 TMEM212
 transmembrane protein 212
chr18_-_25616519 0.14 ENST00000399380.3
 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
chr9_-_135819987 0.14 ENST00000298552.3
ENST00000403810.1
 TSC1
 tuberous sclerosis 1
chr1_+_117602925 0.13 ENST00000369466.4
 TTF2
 transcription termination factor, RNA polymerase II
chr18_+_18943554 0.13 ENST00000580732.2
 GREB1L
 growth regulation by estrogen in breast cancer-like
chr19_-_52531600 0.13 ENST00000356322.6
ENST00000270649.6
 ZNF614
 zinc finger protein 614
chrX_-_70329118 0.13 ENST00000374188.3
 IL2RG
 interleukin 2 receptor, gamma
chr12_+_72080253 0.12 ENST00000549735.1
 TMEM19
 transmembrane protein 19
chr5_+_154092396 0.12 ENST00000336314.4
 LARP1
 La ribonucleoprotein domain family, member 1
chrX_+_57618269 0.11 ENST00000374888.1
 ZXDB
 zinc finger, X-linked, duplicated B
chr3_-_57233966 0.11 ENST00000473921.1
ENST00000295934.3
 HESX1
 HESX homeobox 1
chr9_+_136287444 0.11 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
 ADAMTS13
 ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr6_-_13621126 0.10 ENST00000600057.1
 AL441883.1
 Uncharacterized protein
chr5_+_176853702 0.10 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
 GRK6
 G protein-coupled receptor kinase 6
chr16_+_84178874 0.10 ENST00000378553.5
 DNAAF1
 dynein, axonemal, assembly factor 1
chr17_+_16284604 0.10 ENST00000395839.1
ENST00000395837.1
 UBB
 ubiquitin B
chr5_-_180076580 0.09 ENST00000502649.1
 FLT4
 fms-related tyrosine kinase 4
chr11_-_63933504 0.09 ENST00000255681.6
 MACROD1
 MACRO domain containing 1
chr17_-_29641084 0.09 ENST00000544462.1
 EVI2B
 ecotropic viral integration site 2B
chr18_-_74844727 0.09 ENST00000355994.2
ENST00000579129.1
 MBP
 myelin basic protein
chr1_+_22351977 0.09 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
 LINC00339
 long intergenic non-protein coding RNA 339
chr11_-_34535332 0.08 ENST00000257832.2
ENST00000429939.2
 ELF5
 E74-like factor 5 (ets domain transcription factor)
chr8_-_6420759 0.08 ENST00000523120.1
 ANGPT2
 angiopoietin 2
chr4_-_82393009 0.08 ENST00000436139.2
 RASGEF1B
 RasGEF domain family, member 1B
chr2_+_58134756 0.08 ENST00000435505.2
ENST00000417641.2
 VRK2
 vaccinia related kinase 2
chr21_-_46293644 0.08 ENST00000330938.3
 PTTG1IP
 pituitary tumor-transforming 1 interacting protein
chr12_+_50135327 0.07 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
 TMBIM6
 transmembrane BAX inhibitor motif containing 6
chr15_+_42697018 0.07 ENST00000397204.4
 CAPN3
 calpain 3, (p94)
chr3_+_52245458 0.07 ENST00000459884.1
 ALAS1
 aminolevulinate, delta-, synthase 1
chr12_+_50135351 0.07 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
 TMBIM6
 transmembrane BAX inhibitor motif containing 6
chr17_-_29641104 0.07 ENST00000577894.1
ENST00000330927.4
 EVI2B
 ecotropic viral integration site 2B
chr17_-_8263538 0.07 ENST00000535173.1
 AC135178.1
 HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr6_+_161123270 0.06 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
 PLG
 plasminogen
chr6_+_72922505 0.06 ENST00000401910.3
 RIMS1
 regulating synaptic membrane exocytosis 1
chr2_+_103236004 0.06 ENST00000233969.2
 SLC9A2
 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr7_+_44646218 0.06 ENST00000444676.1
ENST00000222673.5
 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr5_-_19988339 0.06 ENST00000382275.1
 CDH18
 cadherin 18, type 2
chr14_-_21493649 0.06 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
 NDRG2
 NDRG family member 2
chr7_-_140340576 0.05 ENST00000275884.6
ENST00000475837.1
 DENND2A
 DENN/MADD domain containing 2A
chr7_+_116593292 0.05 ENST00000393446.2
ENST00000265437.5
ENST00000393451.3
 ST7
 suppression of tumorigenicity 7
chr6_+_72922590 0.05 ENST00000523963.1
 RIMS1
 regulating synaptic membrane exocytosis 1
chr3_-_49066811 0.05 ENST00000442157.1
ENST00000326739.4
 IMPDH2
 IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_-_128615681 0.05 ENST00000409955.1
ENST00000272645.4
 POLR2D
 polymerase (RNA) II (DNA directed) polypeptide D
chr12_-_114843889 0.04 ENST00000405440.2
 TBX5
 T-box 5
chr12_+_25205666 0.04 ENST00000547044.1
 LRMP
 lymphoid-restricted membrane protein
chr13_+_98086445 0.04 ENST00000245304.4
 RAP2A
 RAP2A, member of RAS oncogene family
chr6_-_160679905 0.04 ENST00000366953.3
 SLC22A2
 solute carrier family 22 (organic cation transporter), member 2
chr6_-_110964453 0.04 ENST00000413605.2
 CDK19
 cyclin-dependent kinase 19
chr18_-_3874271 0.03 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr2_-_220042825 0.03 ENST00000409789.1
 CNPPD1
 cyclin Pas1/PHO80 domain containing 1
chr9_-_134585221 0.03 ENST00000372190.3
ENST00000427994.1
 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
chrX_-_100129320 0.03 ENST00000372966.3
 NOX1
 NADPH oxidase 1
chr9_+_113431059 0.03 ENST00000416899.2
 MUSK
 muscle, skeletal, receptor tyrosine kinase
chr7_-_37026108 0.03 ENST00000396045.3
 ELMO1
 engulfment and cell motility 1
chr3_+_119298523 0.03 ENST00000357003.3
 ADPRH
 ADP-ribosylarginine hydrolase
chr17_+_58755184 0.02 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
 BCAS3
 breast carcinoma amplified sequence 3
chr5_-_142782862 0.02 ENST00000415690.2
 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_-_68033356 0.02 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
 DPEP2
 dipeptidase 2
chr2_-_37193606 0.02 ENST00000379213.2
ENST00000263918.4
 STRN
 striatin, calmodulin binding protein
chr18_-_3874247 0.01 ENST00000581699.1
 DLGAP1
 discs, large (Drosophila) homolog-associated protein 1
chr7_-_144435985 0.01 ENST00000549981.1
 TPK1
 thiamin pyrophosphokinase 1
chr14_+_50234827 0.01 ENST00000554589.1
ENST00000557247.1
 KLHDC2
 kelch domain containing 2
chr4_-_174256276 0.01 ENST00000296503.5
 HMGB2
 high mobility group box 2
chr5_+_150040403 0.01 ENST00000517768.1
ENST00000297130.4
 MYOZ3
 myozenin 3
chr13_-_103053946 0.00 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr8_-_70747205 0.00 ENST00000260126.4
 SLCO5A1
 solute carrier organic anion transporter family, member 5A1

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.4 2.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 1.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.3 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.2 0.7 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 1.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.7 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 3.7 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 4.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0097110 scaffold protein binding(GO:0097110)
0.0 7.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0008513 secondary active organic cation transmembrane transporter activity(GO:0008513)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 1.0 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.9 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 5.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 4.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0043073 germ cell nucleus(GO:0043073)
0.0 10.9 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0060621 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
1.0 3.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.6 2.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.6 1.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.4 1.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.7 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3 3.8 GO:0034378 chylomicron assembly(GO:0034378)
0.3 1.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.3 1.5 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
0.2 2.2 GO:0090232 peripheral nervous system myelin maintenance(GO:0032287) positive regulation of spindle checkpoint(GO:0090232)
0.2 0.8 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 1.1 GO:0044211 CTP salvage(GO:0044211)
0.2 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.1 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.6 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.4 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 2.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.2 GO:1902565 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 3.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.4 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.7 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:2000048 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.9 GO:0019835 cytolysis(GO:0019835)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.4 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.7 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0045577 regulation of B cell differentiation(GO:0045577)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4