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ENCODE cell lines, expression (Ernst 2011)

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Results for FOXO3_FOXD2

Z-value: 1.31

Motif logo

Transcription factors associated with FOXO3_FOXD2

Gene Symbol Gene ID Gene Info
ENSG00000118689.10 FOXO3
ENSG00000186564.5 FOXD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO3hg19_v2_chr6_+_108977520_108977549-0.801.7e-04Click!
FOXD2hg19_v2_chr1_+_47901689_479016890.467.4e-02Click!

Activity profile of FOXO3_FOXD2 motif

Sorted Z-values of FOXO3_FOXD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_99698338 5.39 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr13_-_46716969 5.16 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_80993010 4.88 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr2_-_158345462 4.25 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr13_-_46756351 3.99 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_772901 3.51 ENST00000305108.4
NINJ2
ninjurin 2
chr6_+_135502408 3.46 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr2_+_33661382 3.39 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_135502466 3.33 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr2_-_152146385 2.85 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr14_-_21493649 2.81 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2
NDRG family member 2
chr17_-_29641104 2.60 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr7_-_37026108 2.56 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr6_-_42016385 2.52 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr11_+_10476851 2.52 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr22_+_40342819 2.48 ENST00000407075.3
GRAP2
GRB2-related adaptor protein 2
chr17_+_65373531 2.39 ENST00000580974.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_105416039 2.38 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr17_+_65374075 2.30 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_38721711 2.18 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr8_+_26150628 2.16 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr5_-_137674000 2.10 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr7_+_116654935 2.08 ENST00000432298.1
ENST00000422922.1
ST7
suppression of tumorigenicity 7
chr17_-_29641084 2.07 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr3_-_141868293 2.05 ENST00000317104.7
ENST00000494358.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr5_+_169064245 2.05 ENST00000256935.8
DOCK2
dedicator of cytokinesis 2
chr1_+_111682058 1.94 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr12_-_92539614 1.94 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr6_+_135502501 1.89 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr7_-_140624499 1.87 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr8_-_29208183 1.86 ENST00000240100.2
DUSP4
dual specificity phosphatase 4
chr10_+_97515409 1.85 ENST00000371207.3
ENST00000543964.1
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr6_+_125540951 1.82 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr3_-_33700589 1.79 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr2_-_27435125 1.76 ENST00000414408.1
ENST00000310574.3
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr1_+_192544857 1.76 ENST00000367459.3
ENST00000469578.2
RGS1
regulator of G-protein signaling 1
chr6_-_89927151 1.75 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr10_-_14050522 1.72 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr3_-_33700933 1.72 ENST00000480013.1
CLASP2
cytoplasmic linker associated protein 2
chr3_-_141868357 1.71 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr12_-_102591604 1.65 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr1_-_117210290 1.64 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chr12_-_31479045 1.62 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr9_-_37034028 1.61 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr8_+_99956662 1.58 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr4_-_103266626 1.56 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr1_-_207095324 1.55 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr2_+_58655461 1.53 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr4_-_116034979 1.52 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr12_-_28123206 1.47 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr6_+_6588902 1.46 ENST00000230568.4
LY86
lymphocyte antigen 86
chr12_+_25205666 1.45 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr8_+_11666649 1.45 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_126442563 1.44 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr5_+_176853669 1.41 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr15_+_81589254 1.39 ENST00000394652.2
IL16
interleukin 16
chr10_-_99094458 1.38 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr5_+_176853702 1.33 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr8_-_28243934 1.33 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395
zinc finger protein 395
chr8_+_128748466 1.29 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr17_-_39942940 1.29 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP
junction plakoglobin
chr12_-_28122980 1.28 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr5_-_169725231 1.27 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_-_207095212 1.27 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr16_+_12058961 1.27 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_28124903 1.24 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chr8_+_77593448 1.22 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr15_-_55541227 1.22 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr16_+_12059050 1.22 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr8_+_128748308 1.21 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chrX_-_15619076 1.20 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr16_+_12059091 1.19 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_-_54405773 1.19 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr1_+_199996702 1.19 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr8_-_95449155 1.18 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr14_-_21493884 1.18 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2
NDRG family member 2
chr18_+_57567180 1.18 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr7_+_129906660 1.16 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr5_-_115872142 1.14 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_32121789 1.13 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr1_+_158815588 1.11 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr14_-_36988882 1.11 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr7_-_37024665 1.11 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr9_-_98269481 1.07 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr2_+_86947296 1.07 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr13_-_31038370 1.05 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr11_-_72070206 1.03 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr10_-_43904608 1.03 ENST00000337970.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr7_+_134832808 1.02 ENST00000275767.3
TMEM140
transmembrane protein 140
chr11_-_5526834 1.01 ENST00000380237.1
ENST00000396895.1
ENST00000380252.1
HBE1
HBG2
hemoglobin, epsilon 1
hemoglobin, gamma G
chr6_-_136847099 1.01 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr12_+_6881678 1.01 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr17_+_67410832 1.00 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_32121908 1.00 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr20_+_62795827 1.00 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr2_-_74007193 0.99 ENST00000377706.4
ENST00000443070.1
ENST00000272444.3
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr11_-_108464321 0.99 ENST00000265843.4
EXPH5
exophilin 5
chr20_+_52105495 0.98 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_-_160472952 0.97 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr4_-_153303658 0.96 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_-_172750733 0.96 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr8_-_8318847 0.96 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chrX_-_133792480 0.95 ENST00000359237.4
PLAC1
placenta-specific 1
chr6_-_13621126 0.95 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr1_-_111743285 0.95 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr15_+_41549105 0.94 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr19_-_42916499 0.94 ENST00000601189.1
ENST00000599211.1
LIPE
lipase, hormone-sensitive
chr11_-_108464465 0.94 ENST00000525344.1
EXPH5
exophilin 5
chrX_+_9431324 0.93 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr19_-_39826639 0.93 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr22_+_40322595 0.93 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr2_+_33701286 0.92 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_45212051 0.92 ENST00000372222.3
KIF2C
kinesin family member 2C
chr6_-_136847610 0.92 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr22_+_40322623 0.91 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr5_-_98262240 0.91 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr4_-_140223670 0.91 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr10_-_121296045 0.90 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr2_-_170430277 0.90 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr4_-_123542224 0.89 ENST00000264497.3
IL21
interleukin 21
chr2_-_170430366 0.89 ENST00000453153.2
ENST00000445210.1
FASTKD1
FAST kinase domains 1
chr2_-_165424973 0.89 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr14_-_21493123 0.87 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
NDRG family member 2
chr16_-_4323015 0.87 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_45212074 0.86 ENST00000372217.1
KIF2C
kinesin family member 2C
chr5_-_40755987 0.86 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr4_-_168155169 0.86 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr21_-_43816152 0.86 ENST00000433957.2
ENST00000398397.3
TMPRSS3
transmembrane protease, serine 3
chr5_-_142783175 0.86 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_68592305 0.85 ENST00000234313.7
PLEK
pleckstrin
chr6_-_31550192 0.85 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr17_+_38333263 0.85 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr2_+_143635067 0.85 ENST00000264170.4
KYNU
kynureninase
chr3_+_178866199 0.84 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr15_+_81475047 0.84 ENST00000559388.1
IL16
interleukin 16
chr17_-_42345487 0.83 ENST00000262418.6
SLC4A1
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr9_+_139702363 0.83 ENST00000371663.4
ENST00000371671.4
ENST00000311502.7
RABL6
RAB, member RAS oncogene family-like 6
chr5_-_131132658 0.83 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr4_+_88720698 0.83 ENST00000226284.5
IBSP
integrin-binding sialoprotein
chrX_+_37639302 0.82 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr21_-_33975547 0.82 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr1_+_161136180 0.82 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX
protoporphyrinogen oxidase
chr10_-_43904235 0.82 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_-_112614424 0.81 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr9_-_128246769 0.81 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr7_+_28725585 0.81 ENST00000396298.2
CREB5
cAMP responsive element binding protein 5
chr1_-_114414316 0.80 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr18_-_53070913 0.80 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr5_-_16509101 0.80 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr3_-_57233966 0.79 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr14_-_58894332 0.79 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr11_+_117049910 0.79 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr19_+_859654 0.78 ENST00000592860.1
CFD
complement factor D (adipsin)
chr9_-_3525968 0.77 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr2_-_157198860 0.77 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr3_-_107777208 0.77 ENST00000398258.3
CD47
CD47 molecule
chr1_+_86934526 0.76 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr13_-_99910673 0.76 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chrX_+_37639264 0.76 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chrX_-_48776292 0.76 ENST00000376509.4
PIM2
pim-2 oncogene
chr21_-_34186006 0.75 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr9_+_27109133 0.74 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr6_-_32634425 0.74 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr16_+_30483962 0.74 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr3_+_136649311 0.74 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr8_-_40755333 0.74 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr3_-_168865522 0.74 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr14_+_61788429 0.73 ENST00000332981.5
PRKCH
protein kinase C, eta
chr14_+_32798462 0.73 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_106546808 0.73 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_193853927 0.73 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr9_-_98269699 0.72 ENST00000429896.2
PTCH1
patched 1
chr14_+_60716159 0.72 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_-_202927490 0.71 ENST00000340990.5
ADIPOR1
adiponectin receptor 1
chr8_+_86121448 0.70 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr12_-_53343602 0.70 ENST00000546897.1
ENST00000552551.1
KRT8
keratin 8
chr21_-_43816052 0.70 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr1_-_45956800 0.70 ENST00000538496.1
TESK2
testis-specific kinase 2
chr12_+_25205568 0.70 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr16_+_86612112 0.69 ENST00000320241.3
FOXL1
forkhead box L1
chr16_+_84801852 0.69 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr6_+_34204642 0.69 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr8_-_127570603 0.69 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr12_-_28125638 0.69 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr1_+_65730385 0.68 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_-_49066811 0.68 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr4_+_87928140 0.68 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr1_-_161102213 0.68 ENST00000458050.2
DEDD
death effector domain containing
chr9_+_27109392 0.67 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr7_+_107384142 0.67 ENST00000440859.3
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr12_-_86650045 0.67 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_6603253 0.67 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr6_+_112375462 0.66 ENST00000361714.1
WISP3
WNT1 inducible signaling pathway protein 3
chr12_-_86650077 0.66 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_140223614 0.65 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr8_+_31497271 0.65 ENST00000520407.1
NRG1
neuregulin 1
chr2_-_136875712 0.64 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr5_+_112312416 0.64 ENST00000389063.2
DCP2
decapping mRNA 2
chr2_+_44396000 0.63 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr9_-_98279241 0.63 ENST00000437951.1
ENST00000375274.2
ENST00000430669.2
ENST00000468211.2
PTCH1
patched 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.0 2.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.7 2.2 GO:2000523 dendritic cell dendrite assembly(GO:0097026) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.6 6.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.6 2.4 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.6 9.2 GO:0051639 actin filament network formation(GO:0051639)
0.5 2.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.5 3.2 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.5 1.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.5 1.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 1.4 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.4 3.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 2.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 2.5 GO:0006196 AMP catabolic process(GO:0006196)
0.4 1.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 2.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 1.8 GO:0051182 coenzyme transport(GO:0051182)
0.3 1.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.6 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.3 4.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.3 1.8 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.3 1.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.3 1.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 1.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.3 0.9 GO:0014806 negative regulation of muscle hyperplasia(GO:0014740) smooth muscle hyperplasia(GO:0014806)
0.3 0.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.4 GO:0021759 globus pallidus development(GO:0021759)
0.3 2.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.3 2.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 1.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.3 1.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.3 0.8 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.3 0.8 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 1.3 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.3 1.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 0.5 GO:1905069 allantois development(GO:1905069)
0.2 0.7 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 1.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.6 GO:0032808 lacrimal gland development(GO:0032808)
0.2 0.7 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 1.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 1.1 GO:0030916 otic vesicle formation(GO:0030916)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.7 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.2 0.5 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.5 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 1.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.5 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
0.2 4.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 2.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 0.3 GO:0006533 aspartate catabolic process(GO:0006533)
0.2 1.9 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 0.2 GO:0043132 NAD transport(GO:0043132)
0.2 3.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 1.7 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 1.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 0.7 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 1.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.9 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 1.0 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.7 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 0.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.4 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 3.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.9 GO:0018209 peptidyl-serine modification(GO:0018209)
0.1 0.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.4 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.9 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 2.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.9 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 1.6 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.9 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0050878 regulation of body fluid levels(GO:0050878)
0.1 0.6 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.7 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.5 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.9 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 4.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 4.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:0021764 amygdala development(GO:0021764)
0.1 0.3 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 1.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.9 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.7 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.4 GO:0044336 embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.3 GO:0048686 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.4 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) response to fluoride(GO:1902617)
0.1 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 0.4 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.7 GO:0009266 response to temperature stimulus(GO:0009266) response to heat(GO:0009408) cellular response to heat(GO:0034605)
0.1 0.6 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.0 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.5 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.5 GO:0050918 positive chemotaxis(GO:0050918)
0.1 1.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.9 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 1.8 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.8 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) gamma-delta T cell differentiation(GO:0042492)
0.1 1.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.1 GO:2000381 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) negative regulation of mesoderm development(GO:2000381)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.7 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 2.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 2.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 1.0 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.2 GO:1904317 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.9 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 5.9 GO:0031295 T cell costimulation(GO:0031295)
0.1 1.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 0.9 GO:0008228 opsonization(GO:0008228)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.2 GO:0070858 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) negative regulation of bile acid biosynthetic process(GO:0070858) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 2.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 5.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.3 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.0 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.2 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.7 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.6 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 1.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.6 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.2 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 2.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.0 0.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.6 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.4 GO:0097186 amelogenesis(GO:0097186)
0.0 0.4 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0048753 melanosome organization(GO:0032438) pigment granule organization(GO:0048753)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.5 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 1.3 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0006112 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042)
0.0 0.3 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 1.6 GO:0007631 feeding behavior(GO:0007631)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.6 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.1 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0000820 regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0 0.1 GO:0006979 response to oxidative stress(GO:0006979)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 1.8 GO:0045333 cellular respiration(GO:0045333)
0.0 0.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:1900221 regulation of beta-amyloid clearance(GO:1900221) positive regulation of beta-amyloid clearance(GO:1900223)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 1.1 GO:0035601 protein deacetylation(GO:0006476) protein deacylation(GO:0035601)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.2 GO:0030336 negative regulation of cell migration(GO:0030336)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 9.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.7 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.4 5.4 GO:0042555 MCM complex(GO:0042555)
0.4 1.1 GO:0034657 GID complex(GO:0034657)
0.4 3.5 GO:0045180 basal cortex(GO:0045180)
0.3 2.4 GO:0044294 dendritic growth cone(GO:0044294)
0.3 1.5 GO:0036398 TCR signalosome(GO:0036398)
0.2 0.2 GO:0032982 myosin filament(GO:0032982)
0.2 1.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 0.9 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 4.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 0.3 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 1.0 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.2 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.2 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 7.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 7.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.9 GO:0010008 endosome membrane(GO:0010008)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 2.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 4.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0055037 recycling endosome(GO:0055037)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.7 GO:0005768 endosome(GO:0005768)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 4.4 GO:0005769 early endosome(GO:0005769)
0.0 3.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 2.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.7 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 3.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 6.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 5.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 7.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 5.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 5.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.3 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 7.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.4 REACTOME KINESINS Genes involved in Kinesins
0.1 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 5.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 4.6 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.8 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 7.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 2.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 5.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 10.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 9.0 PID ATR PATHWAY ATR signaling pathway
0.1 2.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 6.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.2 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 3.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.8 8.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.6 1.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.6 1.8 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.5 4.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.5 1.9 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.5 2.4 GO:0097108 hedgehog family protein binding(GO:0097108)
0.4 1.4 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.4 1.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 1.0 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 0.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 1.2 GO:0035276 ethanol binding(GO:0035276)
0.3 1.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 2.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 2.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 4.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.9 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 0.6 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 0.6 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 2.0 GO:0042608 T cell receptor binding(GO:0042608)
0.2 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 1.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 3.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.5 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 1.0 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.0 GO:0030492 hemoglobin binding(GO:0030492)
0.2 4.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.2 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 3.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 6.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.7 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 2.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.8 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.5 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.2 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 1.9 GO:0048156 tau protein binding(GO:0048156)
0.1 0.3 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 1.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) platelet activating factor receptor binding(GO:0031859)
0.1 0.3 GO:0016160 amylase activity(GO:0016160)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.4 GO:0031433 telethonin binding(GO:0031433)
0.1 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 4.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.1 GO:0050699 WW domain binding(GO:0050699)
0.0 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.9 GO:0044212 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 1.0 GO:0097493 muscle alpha-actinin binding(GO:0051371) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0031711 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 3.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 6.9 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 3.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 1.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 1.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0004383 adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)