ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
FOXO4 Links Ensembl NCBI GeneCards UniProt	ENSG00000184481.12	FOXO4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXO4	hg19_v2_chrX_+_70316005_70316047	-0.04	8.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr7_+_134551583	7.17	ENST00000435928.1	CALD1	caldesmon 1
chrX_-_38080077	4.04	ENST00000378533.3 ENST00000544439.1 ENST00000432886.2 ENST00000538295.1	SRPX	sushi-repeat containing protein, X-linked
chr7_-_95064264	3.72	ENST00000536183.1 ENST00000433091.2 ENST00000222572.3	PON2	paraoxonase 2
chr3_+_159570722	3.35	ENST00000482804.1	SCHIP1	schwannomin interacting protein 1
chr14_+_94577074	2.91	ENST00000444961.1 ENST00000448882.1 ENST00000557098.1 ENST00000554800.1 ENST00000556544.1 ENST00000298902.5 ENST00000555819.1 ENST00000557634.1 ENST00000555744.1	IFI27	interferon, alpha-inducible protein 27
chr8_+_31497271	2.71	ENST00000520407.1	NRG1	neuregulin 1
chr8_-_13134045	2.71	ENST00000512044.2	DLC1	deleted in liver cancer 1
chr1_-_227505289	2.66	ENST00000366765.3	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr11_+_844406	2.52	ENST00000397404.1	TSPAN4	tetraspanin 4
chr9_+_706842	2.50	ENST00000382293.3	KANK1	KN motif and ankyrin repeat domains 1
chr18_+_47088401	2.50	ENST00000261292.4 ENST00000427224.2 ENST00000580036.1	LIPG	lipase, endothelial
chr12_+_96588143	2.42	ENST00000228741.3 ENST00000547249.1	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr8_-_141931287	2.34	ENST00000517887.1	PTK2	protein tyrosine kinase 2
chr12_-_10251576	2.33	ENST00000315330.4	CLEC1A	C-type lectin domain family 1, member A
chr8_-_6420930	2.32	ENST00000325203.5	ANGPT2	angiopoietin 2
chr8_-_6420777	2.32	ENST00000415216.1	ANGPT2	angiopoietin 2
chr11_+_844067	2.28	ENST00000397406.1 ENST00000409543.2 ENST00000525201.1	TSPAN4	tetraspanin 4
chr12_-_10251603	2.27	ENST00000457018.2	CLEC1A	C-type lectin domain family 1, member A
chr12_-_71031185	2.18	ENST00000548122.1 ENST00000551525.1 ENST00000550358.1	PTPRB	protein tyrosine phosphatase, receptor type, B
chr10_+_123923105	2.17	ENST00000368999.1	TACC2	transforming, acidic coiled-coil containing protein 2
chr9_+_27109133	2.15	ENST00000519097.1 ENST00000380036.4	TEK	TEK tyrosine kinase, endothelial
chr6_-_105627735	2.13	ENST00000254765.3	POPDC3	popeye domain containing 3
chr2_-_192711968	2.11	ENST00000304141.4	SDPR	serum deprivation response
chr12_-_10251539	2.05	ENST00000420265.2	CLEC1A	C-type lectin domain family 1, member A
chr6_+_123110465	2.00	ENST00000539041.1	SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A
chr4_-_70626430	1.94	ENST00000310613.3	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr4_-_186696425	1.83	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr1_+_145524891	1.63	ENST00000369304.3	ITGA10	integrin, alpha 10
chr10_+_123922941	1.63	ENST00000360561.3	TACC2	transforming, acidic coiled-coil containing protein 2
chr4_-_70626314	1.53	ENST00000510821.1	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr1_-_227505826	1.52	ENST00000334218.5 ENST00000366766.2 ENST00000366764.2	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr8_-_6420565	1.50	ENST00000338312.6	ANGPT2	angiopoietin 2
chr2_-_165424973	1.49	ENST00000543549.1	GRB14	growth factor receptor-bound protein 14
chr4_-_90757364	1.47	ENST00000508895.1	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr12_+_53491220	1.43	ENST00000548547.1 ENST00000301464.3	IGFBP6	insulin-like growth factor binding protein 6
chr2_+_109204909	1.42	ENST00000393310.1	LIMS1	LIM and senescent cell antigen-like domains 1
chr11_-_89224299	1.40	ENST00000343727.5 ENST00000531342.1 ENST00000375979.3	NOX4	NADPH oxidase 4
chr4_-_159080806	1.39	ENST00000590648.1	FAM198B	family with sequence similarity 198, member B
chr4_-_186697044	1.38	ENST00000437304.2	SORBS2	sorbin and SH3 domain containing 2
chr13_-_99630233	1.38	ENST00000376460.1 ENST00000442173.1	DOCK9	dedicator of cytokinesis 9
chr21_+_37507210	1.38	ENST00000290354.5	CBR3	carbonyl reductase 3
chr6_-_46889694	1.37	ENST00000283296.7 ENST00000362015.4 ENST00000456426.2	GPR116	G protein-coupled receptor 116
chr10_+_123923205	1.36	ENST00000369004.3 ENST00000260733.3	TACC2	transforming, acidic coiled-coil containing protein 2
chr11_-_89224139	1.34	ENST00000413594.2	NOX4	NADPH oxidase 4
chr4_+_146403912	1.29	ENST00000507367.1 ENST00000394092.2 ENST00000515385.1	SMAD1	SMAD family member 1
chr11_-_89223883	1.27	ENST00000528341.1	NOX4	NADPH oxidase 4
chr18_-_21852143	1.26	ENST00000399443.3	OSBPL1A	oxysterol binding protein-like 1A
chr4_+_124320665	1.18	ENST00000394339.2	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr13_+_73629107	1.18	ENST00000539231.1	KLF5	Kruppel-like factor 5 (intestinal)
chr1_-_57045228	1.16	ENST00000371250.3	PPAP2B	phosphatidic acid phosphatase type 2B
chr11_-_85780853	1.15	ENST00000531930.1 ENST00000528398.1	PICALM	phosphatidylinositol binding clathrin assembly protein
chr8_-_6420759	1.15	ENST00000523120.1	ANGPT2	angiopoietin 2
chr20_+_44035200	1.13	ENST00000372717.1 ENST00000360981.4	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_-_13175823	1.12	ENST00000545857.1	MPDZ	multiple PDZ domain protein
chr11_+_77532233	1.12	ENST00000525409.1	AAMDC	adipogenesis associated, Mth938 domain containing
chr5_-_125930929	1.11	ENST00000553117.1 ENST00000447989.2 ENST00000409134.3	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr1_-_168106536	1.10	ENST00000537209.1 ENST00000361697.2 ENST00000546300.1 ENST00000367835.1	GPR161	G protein-coupled receptor 161
chr4_-_90756769	1.10	ENST00000345009.4 ENST00000505199.1 ENST00000502987.1	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chr20_+_44035847	1.10	ENST00000372712.2	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_+_27109392	1.06	ENST00000406359.4	TEK	TEK tyrosine kinase, endothelial
chr8_-_134309823	1.05	ENST00000414097.2	NDRG1	N-myc downstream regulated 1
chr12_-_71031220	1.03	ENST00000334414.6	PTPRB	protein tyrosine phosphatase, receptor type, B
chr12_+_96588279	1.02	ENST00000552142.1	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr4_-_111119804	0.98	ENST00000394607.3 ENST00000302274.3	ELOVL6	ELOVL fatty acid elongase 6
chr7_+_12250886	0.97	ENST00000444443.1 ENST00000396667.3	TMEM106B	transmembrane protein 106B
chr2_+_109204743	0.97	ENST00000332345.6	LIMS1	LIM and senescent cell antigen-like domains 1
chr3_-_112127981	0.95	ENST00000486726.2	RP11-231E6.1	RP11-231E6.1
chr18_-_53303123	0.91	ENST00000569357.1 ENST00000565124.1 ENST00000398339.1	TCF4	transcription factor 4
chr8_-_134309335	0.90	ENST00000522890.1 ENST00000323851.7 ENST00000518176.1 ENST00000354944.5 ENST00000537882.1 ENST00000522476.1 ENST00000518066.1 ENST00000521544.1 ENST00000518480.1 ENST00000523892.1	NDRG1	N-myc downstream regulated 1
chr3_+_173302222	0.88	ENST00000361589.4	NLGN1	neuroligin 1
chr16_+_28858004	0.85	ENST00000322610.8	SH2B1	SH2B adaptor protein 1
chr2_-_219157250	0.84	ENST00000434015.2 ENST00000444183.1 ENST00000420341.1 ENST00000453281.1 ENST00000258412.3 ENST00000440422.1	TMBIM1	transmembrane BAX inhibitor motif containing 1
chr4_-_139163491	0.84	ENST00000280612.5	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr11_+_77532155	0.83	ENST00000532481.1 ENST00000526415.1 ENST00000393427.2 ENST00000527134.1 ENST00000304716.8	AAMDC	adipogenesis associated, Mth938 domain containing
chr20_+_45338126	0.83	ENST00000359271.2	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr14_+_96968707	0.81	ENST00000216277.8 ENST00000557320.1 ENST00000557471.1	PAPOLA	poly(A) polymerase alpha
chr3_+_138068051	0.80	ENST00000474559.1	MRAS	muscle RAS oncogene homolog
chr5_+_79703823	0.80	ENST00000338008.5 ENST00000510158.1 ENST00000505560.1	ZFYVE16	zinc finger, FYVE domain containing 16
chr15_-_55657428	0.79	ENST00000568543.1	CCPG1	cell cycle progression 1
chr3_-_28390581	0.78	ENST00000479665.1	AZI2	5-azacytidine induced 2
chr19_-_36523709	0.78	ENST00000592017.1 ENST00000360535.4	CLIP3	CAP-GLY domain containing linker protein 3
chr8_+_70404996	0.77	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr13_-_36944307	0.76	ENST00000355182.4	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr1_+_25664408	0.75	ENST00000374358.4	TMEM50A	transmembrane protein 50A
chr8_-_62602327	0.74	ENST00000445642.3 ENST00000517847.2 ENST00000389204.4 ENST00000517661.1 ENST00000517903.1 ENST00000522603.1 ENST00000522349.1 ENST00000522835.1 ENST00000541428.1 ENST00000518306.1	ASPH	aspartate beta-hydroxylase
chr7_-_115670792	0.73	ENST00000265440.7 ENST00000393485.1	TFEC	transcription factor EC
chr7_+_55177416	0.72	ENST00000450046.1 ENST00000454757.2	EGFR	epidermal growth factor receptor
chr7_+_106505696	0.72	ENST00000440650.2 ENST00000496166.1 ENST00000473541.1	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr2_+_65283529	0.72	ENST00000546106.1 ENST00000537589.1 ENST00000260569.4	CEP68	centrosomal protein 68kDa
chr7_-_115670804	0.71	ENST00000320239.7	TFEC	transcription factor EC
chr6_-_31651817	0.70	ENST00000375863.3 ENST00000375860.2	LY6G5C	lymphocyte antigen 6 complex, locus G5C
chr13_+_32838801	0.69	ENST00000542859.1	FRY	furry homolog (Drosophila)
chr6_+_32121789	0.68	ENST00000437001.2 ENST00000375137.2	PPT2	palmitoyl-protein thioesterase 2
chr17_+_17876127	0.66	ENST00000582416.1 ENST00000313838.8 ENST00000411504.2 ENST00000581264.1 ENST00000399187.1 ENST00000479684.2 ENST00000584166.1 ENST00000585108.1 ENST00000399182.1 ENST00000579977.1	LRRC48	leucine rich repeat containing 48
chr14_-_55878538	0.65	ENST00000247178.5	ATG14	autophagy related 14
chr17_-_17875688	0.64	ENST00000379504.3 ENST00000318094.10 ENST00000540946.1 ENST00000542206.1 ENST00000395739.4 ENST00000581396.1 ENST00000535933.1 ENST00000579586.1	TOM1L2	target of myb1-like 2 (chicken)
chr1_-_43855479	0.64	ENST00000290663.6 ENST00000372457.4	MED8	mediator complex subunit 8
chr17_+_17082842	0.62	ENST00000579361.1	MPRIP	myosin phosphatase Rho interacting protein
chr6_-_31830655	0.62	ENST00000375631.4	NEU1	sialidase 1 (lysosomal sialidase)
chr6_-_167571817	0.61	ENST00000366834.1	GPR31	G protein-coupled receptor 31
chr13_-_36920420	0.60	ENST00000438666.2	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr2_+_233527443	0.60	ENST00000410095.1	EFHD1	EF-hand domain family, member D1
chr2_+_87135076	0.59	ENST00000409776.2	RGPD1	RANBP2-like and GRIP domain containing 1
chr1_-_43855444	0.59	ENST00000372455.4	MED8	mediator complex subunit 8
chr2_+_65283506	0.58	ENST00000377990.2	CEP68	centrosomal protein 68kDa
chr6_+_32121908	0.58	ENST00000375143.2 ENST00000424499.1	PPT2	palmitoyl-protein thioesterase 2
chr6_-_42016385	0.57	ENST00000502771.1 ENST00000508143.1 ENST00000514588.1 ENST00000510503.1 ENST00000415497.2 ENST00000372988.4	CCND3	cyclin D3
chr2_+_66662510	0.56	ENST00000272369.9 ENST00000407092.2	MEIS1	Meis homeobox 1
chr4_-_164534657	0.56	ENST00000339875.5	MARCH1	membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_+_101846664	0.56	ENST00000421544.1 ENST00000413795.1 ENST00000369138.1 ENST00000358361.3	GRIK2	glutamate receptor, ionotropic, kainate 2
chr8_+_120079478	0.55	ENST00000332843.2	COLEC10	collectin sub-family member 10 (C-type lectin)
chr3_-_185826855	0.55	ENST00000306376.5	ETV5	ets variant 5
chr18_+_28898052	0.54	ENST00000257192.4	DSG1	desmoglein 1
chr3_+_138067666	0.51	ENST00000475711.1 ENST00000464896.1	MRAS	muscle RAS oncogene homolog
chr20_-_62582475	0.49	ENST00000369908.5	UCKL1	uridine-cytidine kinase 1-like 1
chr1_-_241803649	0.49	ENST00000366554.2	OPN3	opsin 3
chr20_-_43150601	0.48	ENST00000541235.1 ENST00000255175.1 ENST00000342374.4	SERINC3	serine incorporator 3
chr1_-_241803679	0.47	ENST00000331838.5	OPN3	opsin 3
chr4_-_102268628	0.46	ENST00000323055.6 ENST00000512215.1 ENST00000394854.3	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr16_+_6069072	0.46	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_101504200	0.46	ENST00000422132.1	NXPE3	neurexophilin and PC-esterase domain family, member 3
chr7_+_106505912	0.46	ENST00000359195.3	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr14_+_50234827	0.45	ENST00000554589.1 ENST00000557247.1	KLHDC2	kelch domain containing 2
chr9_+_5510492	0.42	ENST00000397745.2	PDCD1LG2	programmed cell death 1 ligand 2
chr12_-_12491608	0.41	ENST00000545735.1	MANSC1	MANSC domain containing 1
chr2_-_88285309	0.41	ENST00000420840.2	RGPD2	RANBP2-like and GRIP domain containing 2
chr1_+_43855560	0.39	ENST00000562955.1	SZT2	seizure threshold 2 homolog (mouse)
chr5_-_141338627	0.39	ENST00000231484.3	PCDH12	protocadherin 12
chr2_+_175260451	0.38	ENST00000458563.1 ENST00000409673.3 ENST00000272732.6 ENST00000435964.1	SCRN3	secernin 3
chr19_+_17378159	0.38	ENST00000598188.1 ENST00000359435.4 ENST00000599474.1 ENST00000599057.1 ENST00000601043.1 ENST00000447614.2	BABAM1	BRISC and BRCA1 A complex member 1
chr19_+_30863271	0.38	ENST00000355537.3	ZNF536	zinc finger protein 536
chr2_+_12857043	0.38	ENST00000381465.2	TRIB2	tribbles pseudokinase 2
chr1_+_151739131	0.37	ENST00000400999.1	OAZ3	ornithine decarboxylase antizyme 3
chr19_+_17378278	0.36	ENST00000596335.1 ENST00000601436.1 ENST00000595632.1	BABAM1	BRISC and BRCA1 A complex member 1
chr19_+_859425	0.36	ENST00000327726.6	CFD	complement factor D (adipsin)
chr2_-_71454185	0.35	ENST00000244221.8	PAIP2B	poly(A) binding protein interacting protein 2B
chrX_-_20236970	0.35	ENST00000379548.4	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr18_-_53069419	0.33	ENST00000570177.2	TCF4	transcription factor 4
chr19_-_58662139	0.33	ENST00000598312.1	ZNF329	zinc finger protein 329
chr3_-_18466026	0.33	ENST00000417717.2	SATB1	SATB homeobox 1
chr1_-_57431679	0.33	ENST00000371237.4 ENST00000535057.1 ENST00000543257.1	C8B	complement component 8, beta polypeptide
chr2_+_201980827	0.33	ENST00000309955.3 ENST00000443227.1 ENST00000341222.6 ENST00000355558.4 ENST00000340870.5 ENST00000341582.6	CFLAR	CASP8 and FADD-like apoptosis regulator
chr3_+_132316081	0.32	ENST00000249887.2	ACKR4	atypical chemokine receptor 4
chr19_+_859654	0.32	ENST00000592860.1	CFD	complement factor D (adipsin)
chr5_-_59064458	0.32	ENST00000502575.1 ENST00000507116.1	PDE4D	phosphodiesterase 4D, cAMP-specific
chr2_-_101767715	0.31	ENST00000376840.4 ENST00000409318.1	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr16_+_6069586	0.31	ENST00000547372.1	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_88754069	0.30	ENST00000395102.4 ENST00000497649.2	MEPE	matrix extracellular phosphoglycoprotein
chr8_+_19171128	0.30	ENST00000265807.3	SH2D4A	SH2 domain containing 4A
chr1_-_153514241	0.30	ENST00000368718.1 ENST00000359215.1	S100A5	S100 calcium binding protein A5
chr1_-_53608249	0.30	ENST00000371494.4	SLC1A7	solute carrier family 1 (glutamate transporter), member 7
chr6_-_117747015	0.30	ENST00000368508.3 ENST00000368507.3	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr17_+_72426891	0.30	ENST00000392627.1	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr1_+_28879588	0.29	ENST00000373830.3	TRNAU1AP	tRNA selenocysteine 1 associated protein 1
chr9_+_5510558	0.29	ENST00000397747.3	PDCD1LG2	programmed cell death 1 ligand 2
chr2_+_12857015	0.29	ENST00000155926.4	TRIB2	tribbles pseudokinase 2
chr1_+_73771844	0.29	ENST00000440762.1 ENST00000444827.1 ENST00000415686.1 ENST00000411903.1	RP4-598G3.1	RP4-598G3.1
chr10_+_99400443	0.29	ENST00000370631.3	PI4K2A	phosphatidylinositol 4-kinase type 2 alpha
chr1_+_6845384	0.28	ENST00000303635.7	CAMTA1	calmodulin binding transcription activator 1
chr1_+_86934526	0.28	ENST00000394711.1	CLCA1	chloride channel accessory 1
chr3_+_48956249	0.28	ENST00000452882.1 ENST00000430423.1 ENST00000356401.4 ENST00000449376.1 ENST00000420814.1 ENST00000449729.1 ENST00000433170.1	ARIH2	ariadne RBR E3 ubiquitin protein ligase 2
chr7_-_6098770	0.27	ENST00000536084.1 ENST00000446699.1 ENST00000199389.6	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1
chr3_+_130569592	0.26	ENST00000533801.2	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr14_+_96968802	0.26	ENST00000556619.1 ENST00000392990.2	PAPOLA	poly(A) polymerase alpha
chr4_+_88754113	0.25	ENST00000560249.1 ENST00000540395.1 ENST00000511670.1 ENST00000361056.3	MEPE	matrix extracellular phosphoglycoprotein
chr7_-_38394118	0.25	ENST00000390345.2	TRGV4	T cell receptor gamma variable 4
chr11_-_114466471	0.25	ENST00000424261.2	NXPE4	neurexophilin and PC-esterase domain family, member 4
chr9_+_134000948	0.25	ENST00000359428.5 ENST00000411637.2 ENST00000451030.1	NUP214	nucleoporin 214kDa
chrX_-_148676974	0.24	ENST00000524178.1	HSFX2	heat shock transcription factor family, X linked 2
chr14_+_22985251	0.23	ENST00000390510.1	TRAJ27	T cell receptor alpha joining 27
chrX_+_148855726	0.23	ENST00000370416.4	HSFX1	heat shock transcription factor family, X linked 1
chr7_+_101460882	0.23	ENST00000292535.7 ENST00000549414.2 ENST00000550008.2 ENST00000546411.2 ENST00000556210.1	CUX1	cut-like homeobox 1
chr19_-_40791302	0.23	ENST00000392038.2 ENST00000578123.1	AKT2	v-akt murine thymoma viral oncogene homolog 2
chr13_-_41240717	0.23	ENST00000379561.5	FOXO1	forkhead box O1
chr1_+_154193325	0.22	ENST00000428931.1 ENST00000441890.1 ENST00000271877.7 ENST00000412596.1 ENST00000368504.1 ENST00000437652.1	UBAP2L	ubiquitin associated protein 2-like
chr16_-_28608424	0.22	ENST00000335715.4	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr15_+_43985725	0.21	ENST00000413453.2	CKMT1A	creatine kinase, mitochondrial 1A
chr5_-_133510456	0.21	ENST00000520417.1	SKP1	S-phase kinase-associated protein 1
chr10_+_111985713	0.21	ENST00000239007.7	MXI1	MAX interactor 1, dimerization protein
chr5_+_140529630	0.21	ENST00000543635.1	PCDHB6	protocadherin beta 6
chr17_+_44668035	0.21	ENST00000398238.4 ENST00000225282.8	NSF	N-ethylmaleimide-sensitive factor
chr19_-_40732594	0.20	ENST00000430325.2 ENST00000433940.1	CNTD2	cyclin N-terminal domain containing 2
chr11_-_10879572	0.20	ENST00000413761.2	ZBED5	zinc finger, BED-type containing 5
chr16_+_14980632	0.20	ENST00000565655.1	NOMO1	NODAL modulator 1
chr11_+_46638805	0.20	ENST00000434074.1 ENST00000312040.4 ENST00000451945.1	ATG13	autophagy related 13
chr3_+_130569429	0.20	ENST00000505330.1 ENST00000504381.1 ENST00000507488.2 ENST00000393221.4	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr5_+_162932554	0.19	ENST00000321757.6 ENST00000421814.2 ENST00000518095.1	MAT2B	methionine adenosyltransferase II, beta
chr11_-_114466477	0.19	ENST00000375478.3	NXPE4	neurexophilin and PC-esterase domain family, member 4
chr7_-_38389573	0.19	ENST00000390344.2	TRGV5	T cell receptor gamma variable 5
chr1_+_24018269	0.18	ENST00000374550.3	RPL11	ribosomal protein L11
chr10_-_118032697	0.18	ENST00000439649.3	GFRA1	GDNF family receptor alpha 1
chr16_-_28857677	0.18	ENST00000313511.3	TUFM	Tu translation elongation factor, mitochondrial
chr3_-_150920979	0.18	ENST00000309180.5 ENST00000480322.1	GPR171	G protein-coupled receptor 171
chr6_-_87804815	0.17	ENST00000369582.2	CGA	glycoprotein hormones, alpha polypeptide
chr4_-_70518941	0.17	ENST00000286604.4 ENST00000505512.1 ENST00000514019.1	UGT2A1 UGT2A1	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr9_-_15472730	0.17	ENST00000481862.1	PSIP1	PC4 and SFRS1 interacting protein 1
chr15_-_58571445	0.17	ENST00000558231.1	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr10_-_118032979	0.17	ENST00000355422.6	GFRA1	GDNF family receptor alpha 1
chr1_-_182360498	0.16	ENST00000417584.2	GLUL	glutamate-ammonia ligase
chr4_+_74347400	0.16	ENST00000226355.3	AFM	afamin

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	7.3	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
1.1	3.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.8	2.5	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.6	2.5	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.5	2.6	GO:2000470	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.5	4.0	GO:0001845	phagolysosome assembly(GO:0001845) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4	1.2	GO:0060940	epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.4	1.2	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.4	2.7	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3	1.4	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3	0.9	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3	1.4	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.3	2.3	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.2	0.7	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2	0.7	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2	0.8	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	2.7	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.2	2.0	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.2	2.2	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.2	1.2	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2	1.0	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2	3.7	GO:0019372	lipoxygenase pathway(GO:0019372)
0.2	0.8	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	1.3	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.2	0.8	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	0.5	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.1	3.7	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	1.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	1.0	GO:0042426	choline catabolic process(GO:0042426)
0.1	0.7	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	1.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.7	GO:0016240	autophagosome docking(GO:0016240)
0.1	4.0	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.6	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	1.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.4	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.1	0.3	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.1	1.1	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1	0.3	GO:0006447	regulation of translational initiation by iron(GO:0006447)
0.1	0.7	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	0.5	GO:0044211	CTP salvage(GO:0044211)
0.1	0.5	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	0.3	GO:0006542	glutamine biosynthetic process(GO:0006542)
0.1	0.6	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	2.9	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.1	0.2	GO:1902617	response to fluoride(GO:1902617)
0.1	0.3	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	1.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.5	GO:0009597	detection of virus(GO:0009597)
0.1	1.3	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	0.3	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	1.0	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	2.4	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.1	0.7	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	1.5	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0	1.4	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.7	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	1.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	1.0	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.2	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.3	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	1.5	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	5.2	GO:0021987	cerebral cortex development(GO:0021987)
0.0	0.3	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.1	GO:1900535	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0	0.2	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	0.6	GO:0060044	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.8	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.7	GO:0032607	interferon-alpha production(GO:0032607)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	1.3	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.4	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	1.7	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.3	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.8	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	1.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.2	GO:0035799	ureter maturation(GO:0035799)
0.0	1.0	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.6	GO:0046626	regulation of insulin receptor signaling pathway(GO:0046626)
0.0	0.2	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.2	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.3	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.0	0.5	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.0	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0	0.3	GO:0060004	reflex(GO:0060004)
0.0	2.0	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.8	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.8	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.8	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.0	0.1	GO:0097242	beta-amyloid clearance(GO:0097242)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.2	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.2	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.6	GO:0050918	positive chemotaxis(GO:0050918)
0.0	0.2	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0034680	integrin alpha10-beta1 complex(GO:0034680)
0.5	7.2	GO:0030478	actin cap(GO:0030478)
0.4	1.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2	0.7	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.2	4.0	GO:0043020	NADPH oxidase complex(GO:0043020)
0.2	0.7	GO:1903349	omegasome membrane(GO:1903349)
0.2	1.2	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	0.7	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	0.7	GO:0070552	BRISC complex(GO:0070552)
0.1	2.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	2.7	GO:0030673	axolemma(GO:0030673)
0.1	9.7	GO:0042641	actomyosin(GO:0042641)
0.1	0.3	GO:0035838	growing cell tip(GO:0035838)
0.1	0.5	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.4	GO:1990130	Iml1 complex(GO:1990130)
0.1	0.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	4.2	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	1.1	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.3	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.4	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	4.2	GO:0035579	specific granule membrane(GO:0035579)
0.0	1.2	GO:0016592	mediator complex(GO:0016592)
0.0	0.2	GO:0001940	male pronucleus(GO:0001940)
0.0	4.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	3.3	GO:0005776	autophagosome(GO:0005776)
0.0	1.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	2.2	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.3	GO:0097386	glial cell projection(GO:0097386)
0.0	0.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.6	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	11.6	GO:0005925	focal adhesion(GO:0005925)
0.0	0.3	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0097342	ripoptosome(GO:0097342)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0	1.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	1.4	GO:0055037	recycling endosome(GO:0055037)
0.0	1.8	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	1.4	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	1.1	GO:0001750	photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
1.1	3.4	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.5	2.6	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.5	1.4	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.4	4.0	GO:0019826	oxygen sensor activity(GO:0019826)
0.3	1.6	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	2.5	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.3	2.7	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.3	7.2	GO:0005523	tropomyosin binding(GO:0005523)
0.2	2.0	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.2	0.8	GO:0097001	ceramide binding(GO:0097001)
0.2	0.8	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	1.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	0.8	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	1.0	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2	3.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.2	1.3	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.6	GO:0052796	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	2.3	GO:0008432	JUN kinase binding(GO:0008432)
0.1	1.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	8.8	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	3.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	3.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.1	1.2	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	1.0	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	1.2	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	2.6	GO:0005521	lamin binding(GO:0005521)
0.1	0.3	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	1.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.3	GO:0016880	glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1	0.6	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.3	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	0.5	GO:0004849	uridine kinase activity(GO:0004849)
0.1	2.7	GO:0042169	SH2 domain binding(GO:0042169)
0.1	2.0	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	0.3	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.8	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	2.5	GO:0030552	cAMP binding(GO:0030552)
0.1	1.3	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.3	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.5	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.8	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.5	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	1.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	3.5	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.5	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	1.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	1.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.6	GO:0005537	mannose binding(GO:0005537)
0.0	2.5	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.7	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	0.7	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	5.1	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.0	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	3.2	GO:0005178	integrin binding(GO:0005178)
0.0	6.4	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	3.6	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.6	GO:0030276	clathrin binding(GO:0030276)
0.0	1.2	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	3.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	2.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	3.0	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	6.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	2.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	3.4	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	5.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	2.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.2	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.9	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	12.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	0.7	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	3.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	6.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.0	REACTOME OPSINS	Genes involved in Opsins
0.1	2.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	1.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.6	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	1.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.7	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.6	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	2.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	2.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	2.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.7	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.8	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	1.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.8	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.6	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.0	1.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors