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ENCODE cell lines, expression (Ernst 2011)

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Results for FUBP1

Z-value: 0.94

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Transcription factors associated with FUBP1

Gene Symbol Gene ID Gene Info
FUBP1
ENSG00000162613.12 FUBP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FUBP1hg19_v2_chr1_-_78444738_78444773-0.146.1e-01Click!

Activity profile of FUBP1 motif

Sorted Z-values of FUBP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FUBP1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_53255766 3.82 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
 TCF4
 transcription factor 4
chr7_+_116166331 3.09 ENST00000393468.1
ENST00000393467.1
 CAV1
 caveolin 1, caveolae protein, 22kDa
chr11_-_33891362 2.79 ENST00000395833.3
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr12_+_48513570 2.22 ENST00000551804.1
 PFKM
 phosphofructokinase, muscle
chr6_+_121756809 2.22 ENST00000282561.3
 GJA1
 gap junction protein, alpha 1, 43kDa
chr7_-_87849340 2.13 ENST00000419179.1
ENST00000265729.2
 SRI
 sorcin
chr15_+_49170083 1.86 ENST00000530028.2
 EID1
 EP300 interacting inhibitor of differentiation 1
chr2_+_33359646 1.76 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_+_33359687 1.75 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr4_-_16900242 1.49 ENST00000502640.1
ENST00000506732.1
 LDB2
 LIM domain binding 2
chr4_-_25865159 1.36 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_-_16900184 1.27 ENST00000515064.1
 LDB2
 LIM domain binding 2
chr1_+_84609944 1.26 ENST00000370685.3
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr4_-_16900217 1.25 ENST00000441778.2
 LDB2
 LIM domain binding 2
chr4_-_16900410 1.21 ENST00000304523.5
 LDB2
 LIM domain binding 2
chr4_-_101439242 1.15 ENST00000296420.4
 EMCN
 endomucin
chr4_-_101439148 1.11 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
 EMCN
 endomucin
chr14_+_61654271 0.94 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr7_-_124405681 0.92 ENST00000303921.2
 GPR37
 G protein-coupled receptor 37 (endothelin receptor type B-like)
chr15_-_55657428 0.82 ENST00000568543.1
 CCPG1
 cell cycle progression 1
chr1_+_43766642 0.81 ENST00000372476.3
 TIE1
 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr9_+_82186872 0.77 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr8_+_94929969 0.75 ENST00000517764.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_-_120685608 0.73 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr3_-_167452298 0.69 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
 PDCD10
 programmed cell death 10
chr6_+_125524785 0.65 ENST00000392482.2
 TPD52L1
 tumor protein D52-like 1
chrX_+_119737806 0.64 ENST00000371317.5
 MCTS1
 malignant T cell amplified sequence 1
chr3_-_167452262 0.62 ENST00000487947.2
 PDCD10
 programmed cell death 10
chr11_+_60681346 0.60 ENST00000227525.3
 TMEM109
 transmembrane protein 109
chr9_-_113761720 0.55 ENST00000541779.1
ENST00000374430.2
 LPAR1
 lysophosphatidic acid receptor 1
chr7_-_144435985 0.55 ENST00000549981.1
 TPK1
 thiamin pyrophosphokinase 1
chr9_-_110251836 0.55 ENST00000374672.4
 KLF4
 Kruppel-like factor 4 (gut)
chr12_-_91576561 0.55 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr7_-_83824169 0.55 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr21_+_30502806 0.54 ENST00000399928.1
ENST00000399926.1
 MAP3K7CL
 MAP3K7 C-terminal like
chr3_+_173302222 0.51 ENST00000361589.4
 NLGN1
 neuroligin 1
chr12_-_57522813 0.51 ENST00000556155.1
 STAT6
 signal transducer and activator of transcription 6, interleukin-4 induced
chr9_+_82186682 0.50 ENST00000376552.2
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chrX_+_95939638 0.49 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
 DIAPH2
 diaphanous-related formin 2
chr19_+_36235964 0.48 ENST00000587708.2
 PSENEN
 presenilin enhancer gamma secretase subunit
chr12_-_91576429 0.48 ENST00000552145.1
ENST00000546745.1
 DCN
 decorin
chr7_-_144533074 0.46 ENST00000360057.3
ENST00000378099.3
 TPK1
 thiamin pyrophosphokinase 1
chr15_+_52155001 0.44 ENST00000544199.1
 TMOD3
 tropomodulin 3 (ubiquitous)
chr21_-_37451680 0.43 ENST00000399201.1
 SETD4
 SET domain containing 4
chr3_-_169587621 0.41 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
 LRRC31
 leucine rich repeat containing 31
chr12_+_10365404 0.41 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
 GABARAPL1
 GABA(A) receptor-associated protein like 1
chr12_+_56324756 0.40 ENST00000331886.5
ENST00000555090.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr3_+_186383741 0.38 ENST00000232003.4
 HRG
 histidine-rich glycoprotein
chrX_+_52235228 0.37 ENST00000518075.1
 XAGE1B
 X antigen family, member 1B
chr4_-_100242549 0.37 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr4_-_84205905 0.37 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
 COQ2
 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr11_+_34073195 0.37 ENST00000341394.4
 CAPRIN1
 cell cycle associated protein 1
chrX_+_95939711 0.36 ENST00000373049.4
ENST00000324765.8
 DIAPH2
 diaphanous-related formin 2
chr1_-_44818599 0.35 ENST00000537474.1
 ERI3
 ERI1 exoribonuclease family member 3
chr5_-_34919094 0.35 ENST00000341754.4
 RAD1
 RAD1 homolog (S. pombe)
chr17_-_8151353 0.34 ENST00000315684.8
 CTC1
 CTS telomere maintenance complex component 1
chr15_+_49462397 0.33 ENST00000396509.2
 GALK2
 galactokinase 2
chr1_-_43855479 0.31 ENST00000290663.6
ENST00000372457.4
 MED8
 mediator complex subunit 8
chr6_-_111888474 0.31 ENST00000368735.1
 TRAF3IP2
 TRAF3 interacting protein 2
chr19_+_19303008 0.31 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
 RFXANK
 regulatory factor X-associated ankyrin-containing protein
chr15_+_49462434 0.31 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
 GALK2
 galactokinase 2
chr3_-_112127981 0.29 ENST00000486726.2
 RP11-231E6.1
 RP11-231E6.1
chr5_+_140027355 0.28 ENST00000417647.2
ENST00000507593.1
ENST00000508301.1
 IK
 IK cytokine, down-regulator of HLA II
chr4_-_99850243 0.27 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
 EIF4E
 eukaryotic translation initiation factor 4E
chr12_-_85306594 0.24 ENST00000266682.5
 SLC6A15
 solute carrier family 6 (neutral amino acid transporter), member 15
chr1_-_161207986 0.22 ENST00000506209.1
ENST00000367980.2
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr12_-_110888103 0.22 ENST00000426440.1
ENST00000228825.7
 ARPC3
 actin related protein 2/3 complex, subunit 3, 21kDa
chr2_-_26205340 0.22 ENST00000264712.3
 KIF3C
 kinesin family member 3C
chr3_-_47950745 0.22 ENST00000429422.1
 MAP4
 microtubule-associated protein 4
chr1_-_161208013 0.21 ENST00000515452.1
ENST00000367983.4
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr3_+_19988566 0.20 ENST00000273047.4
 RAB5A
 RAB5A, member RAS oncogene family
chr10_-_70092671 0.19 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
 PBLD
 phenazine biosynthesis-like protein domain containing
chr1_-_43855444 0.18 ENST00000372455.4
 MED8
 mediator complex subunit 8
chr16_+_532503 0.17 ENST00000412256.1
 RAB11FIP3
 RAB11 family interacting protein 3 (class II)
chr6_-_56507586 0.16 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
 DST
 dystonin
chr4_+_170581213 0.15 ENST00000507875.1
 CLCN3
 chloride channel, voltage-sensitive 3
chr5_-_88178964 0.14 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
 MEF2C
 myocyte enhancer factor 2C
chr2_+_113033164 0.14 ENST00000409871.1
ENST00000343936.4
 ZC3H6
 zinc finger CCCH-type containing 6
chr4_-_164534657 0.14 ENST00000339875.5
 MARCH1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr10_-_105845674 0.13 ENST00000353479.5
ENST00000369733.3
 COL17A1
 collagen, type XVII, alpha 1
chr2_-_228497888 0.13 ENST00000264387.4
ENST00000409066.1
 C2orf83
 chromosome 2 open reading frame 83
chr2_-_169746878 0.13 ENST00000282074.2
 SPC25
 SPC25, NDC80 kinetochore complex component
chr12_+_16109519 0.13 ENST00000526530.1
 DERA
 deoxyribose-phosphate aldolase (putative)
chr2_+_201980827 0.13 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr14_+_89060739 0.12 ENST00000318308.6
 ZC3H14
 zinc finger CCCH-type containing 14
chr1_+_43855560 0.11 ENST00000562955.1
 SZT2
 seizure threshold 2 homolog (mouse)
chr12_+_56324933 0.11 ENST00000549629.1
ENST00000555218.1
 DGKA
 diacylglycerol kinase, alpha 80kDa
chr5_-_88179017 0.10 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
 MEF2C
 myocyte enhancer factor 2C
chr21_-_38445297 0.09 ENST00000430792.1
ENST00000399103.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr21_-_38445011 0.09 ENST00000464265.1
ENST00000399102.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr17_+_67498538 0.08 ENST00000589647.1
 MAP2K6
 mitogen-activated protein kinase kinase 6
chr1_-_27701307 0.08 ENST00000270879.4
ENST00000354982.2
 FCN3
 ficolin (collagen/fibrinogen domain containing) 3
chr11_-_10590238 0.07 ENST00000256178.3
 LYVE1
 lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_115238207 0.07 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
 AMPD1
 adenosine monophosphate deaminase 1
chr19_+_13134772 0.07 ENST00000587760.1
ENST00000585575.1
 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
chr8_-_101719159 0.07 ENST00000520868.1
ENST00000522658.1
 PABPC1
 poly(A) binding protein, cytoplasmic 1
chr15_+_80364901 0.07 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr7_-_74267836 0.07 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
 GTF2IRD2
 GTF2I repeat domain containing 2
chrX_-_65259914 0.07 ENST00000374737.4
ENST00000455586.2
 VSIG4
 V-set and immunoglobulin domain containing 4
chr11_-_107590383 0.06 ENST00000525934.1
ENST00000531293.1
 SLN
 sarcolipin
chr5_-_1882858 0.06 ENST00000511126.1
ENST00000231357.2
 IRX4
 iroquois homeobox 4
chr1_-_216978709 0.06 ENST00000360012.3
 ESRRG
 estrogen-related receptor gamma
chr11_+_98891797 0.06 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
 CNTN5
 contactin 5
chrX_-_65259900 0.05 ENST00000412866.2
 VSIG4
 V-set and immunoglobulin domain containing 4
chr14_+_65878565 0.05 ENST00000556518.1
ENST00000557164.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr7_+_74508372 0.04 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
 GTF2IRD2B
 GTF2I repeat domain containing 2B
chr13_+_49551020 0.04 ENST00000541916.1
 FNDC3A
 fibronectin type III domain containing 3A
chr18_-_60986613 0.03 ENST00000444484.1
 BCL2
 B-cell CLL/lymphoma 2
chr11_+_64004888 0.03 ENST00000541681.1
 VEGFB
 vascular endothelial growth factor B
chr4_-_48136217 0.03 ENST00000264316.4
 TXK
 TXK tyrosine kinase
chr7_+_129710350 0.02 ENST00000335420.5
ENST00000463413.1
 KLHDC10
 kelch domain containing 10
chr2_-_183291741 0.02 ENST00000351439.5
ENST00000409365.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr10_+_51187938 0.02 ENST00000311663.5
 FAM21D
 family with sequence similarity 21, member D
chr7_+_141811539 0.02 ENST00000550469.2
ENST00000477922.3
 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
chr11_+_120207787 0.02 ENST00000397843.2
ENST00000356641.3
 ARHGEF12
 Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_181452678 0.02 ENST00000367570.1
ENST00000526775.1
ENST00000357570.5
ENST00000358338.5
ENST00000367567.4
 CACNA1E
 calcium channel, voltage-dependent, R type, alpha 1E subunit
chr2_+_181845843 0.01 ENST00000602710.1
 UBE2E3
 ubiquitin-conjugating enzyme E2E 3
chr14_-_24711865 0.00 ENST00000399423.4
ENST00000267415.7
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 2.1 GO:0044326 dendritic spine neck(GO:0044326)
0.2 3.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 3.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 2.2 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 10.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0036019 endolysosome(GO:0036019)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 2.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.7 2.2 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.4 3.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3 2.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.3 1.3 GO:0097338 response to clozapine(GO:0097338)
0.3 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.2 5.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 0.5 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.2 0.5 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.2 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 2.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 0.5 GO:0048880 sensory system development(GO:0048880)
0.1 0.9 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.1 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.6 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.5 GO:0031293 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 1.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 4.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.7 3.5 GO:0050436 microfibril binding(GO:0050436)
0.5 5.2 GO:0030274 LIM domain binding(GO:0030274)
0.4 2.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.4 2.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 3.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.0 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0004882 androgen receptor activity(GO:0004882)
0.1 2.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 1.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 3.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 4.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling