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ENCODE cell lines, expression (Ernst 2011)

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Results for GATA1_GATA4

Z-value: 2.04

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
GATA1
ENSG00000102145.9 GATA1
GATA4
ENSG00000136574.13 GATA4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.792.9e-04Click!
GATA4hg19_v2_chr8_+_11534462_11534475,
hg19_v2_chr8_+_11561660_11561751		-0.029.4e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_202686 7.93 ENST00000252951.2
 HBZ
 hemoglobin, zeta
chr19_-_13213662 6.71 ENST00000264824.4
 LYL1
 lymphoblastic leukemia derived sequence 1
chr12_-_54689532 6.31 ENST00000540264.2
ENST00000312156.4
 NFE2
 nuclear factor, erythroid 2
chr17_-_62084241 5.18 ENST00000449662.2
 ICAM2
 intercellular adhesion molecule 2
chrX_-_78622805 4.28 ENST00000373298.2
 ITM2A
 integral membrane protein 2A
chr19_+_10397621 4.12 ENST00000380770.3
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_+_10397648 4.06 ENST00000340992.4
ENST00000393717.2
 ICAM4
 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_-_55669093 3.71 ENST00000344887.5
 TNNI3
 troponin I type 3 (cardiac)
chr21_-_15918618 3.43 ENST00000400564.1
ENST00000400566.1
 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_5271122 3.42 ENST00000330597.3
 HBG1
 hemoglobin, gamma A
chr19_-_12997995 3.39 ENST00000264834.4
 KLF1
 Kruppel-like factor 1 (erythroid)
chr1_+_25598989 3.32 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chr11_+_118958689 3.24 ENST00000535253.1
ENST00000392841.1
 HMBS
 hydroxymethylbilane synthase
chr7_-_100239132 3.19 ENST00000223051.3
ENST00000431692.1
 TFR2
 transferrin receptor 2
chr10_+_70847852 3.18 ENST00000242465.3
 SRGN
 serglycin
chr7_-_150652924 3.17 ENST00000330883.4
 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_-_141061759 2.56 ENST00000508305.1
 ARAP3
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr5_-_141061777 2.44 ENST00000239440.4
 ARAP3
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_-_6233828 2.39 ENST00000572068.1
ENST00000261405.5
 VWF
 von Willebrand factor
chr1_+_161136180 2.24 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
 PPOX
 protoporphyrinogen oxidase
chr1_-_225616515 2.23 ENST00000338179.2
ENST00000425080.1
 LBR
 lamin B receptor
chr1_+_25598872 2.23 ENST00000328664.4
 RHD
 Rh blood group, D antigen
chr7_-_50860565 2.20 ENST00000403097.1
 GRB10
 growth factor receptor-bound protein 10
chr4_-_144940477 2.12 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
 GYPB
 glycophorin B (MNS blood group)
chr15_-_58306295 2.12 ENST00000559517.1
 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
chr6_-_31846744 2.10 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
 SLC44A4
 solute carrier family 44, member 4
chr1_+_25599018 2.09 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
 RHD
 Rh blood group, D antigen
chr4_-_103266355 2.08 ENST00000424970.2
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr9_+_139557360 2.05 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
 EGFL7
 EGF-like-domain, multiple 7
chr1_-_25747283 2.03 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
 RHCE
 Rh blood group, CcEe antigens
chr8_+_21823726 2.03 ENST00000433566.4
 XPO7
 exportin 7
chr1_-_225615599 1.97 ENST00000421383.1
ENST00000272163.4
 LBR
 lamin B receptor
chr3_+_169629354 1.89 ENST00000428432.2
ENST00000335556.3
 SAMD7
 sterile alpha motif domain containing 7
chr3_-_98312548 1.79 ENST00000264193.2
 CPOX
 coproporphyrinogen oxidase
chr11_+_128563652 1.73 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr1_+_198608146 1.71 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
 PTPRC
 protein tyrosine phosphatase, receptor type, C
chr11_-_5255861 1.70 ENST00000380299.3
 HBD
 hemoglobin, delta
chr8_+_56014949 1.69 ENST00000327381.6
 XKR4
 XK, Kell blood group complex subunit-related family, member 4
chr12_-_71148413 1.65 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr12_-_71148357 1.64 ENST00000378778.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr2_+_102928009 1.62 ENST00000404917.2
ENST00000447231.1
 IL1RL1
 interleukin 1 receptor-like 1
chr8_-_38008783 1.60 ENST00000276449.4
 STAR
 steroidogenic acute regulatory protein
chr6_+_12290586 1.58 ENST00000379375.5
 EDN1
 endothelin 1
chrX_+_65382433 1.57 ENST00000374727.3
 HEPH
 hephaestin
chr17_-_47841485 1.57 ENST00000506156.1
ENST00000240364.2
 FAM117A
 family with sequence similarity 117, member A
chr1_-_155270770 1.56 ENST00000392414.3
 PKLR
 pyruvate kinase, liver and RBC
chr2_+_201994042 1.54 ENST00000417748.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr17_+_37824217 1.54 ENST00000394246.1
 PNMT
 phenylethanolamine N-methyltransferase
chrX_-_55057403 1.54 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
 ALAS2
 aminolevulinate, delta-, synthase 2
chr4_-_144826682 1.53 ENST00000358615.4
ENST00000437468.2
 GYPE
 glycophorin E (MNS blood group)
chr3_-_119379719 1.46 ENST00000493094.1
 POPDC2
 popeye domain containing 2
chr3_+_151986709 1.43 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
 MBNL1
 muscleblind-like splicing regulator 1
chr11_-_57158109 1.42 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
 PRG2
 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr10_+_28822636 1.40 ENST00000442148.1
ENST00000448193.1
 WAC
 WW domain containing adaptor with coiled-coil
chr4_-_145061788 1.38 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
 GYPA
GYPB
 glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr17_+_74381343 1.36 ENST00000392496.3
 SPHK1
 sphingosine kinase 1
chr2_+_189156586 1.36 ENST00000409830.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr11_-_5255696 1.35 ENST00000292901.3
ENST00000417377.1
 HBD
 hemoglobin, delta
chr10_+_71075552 1.34 ENST00000298649.3
 HK1
 hexokinase 1
chr3_-_168864427 1.32 ENST00000468789.1
 MECOM
 MDS1 and EVI1 complex locus
chr4_-_103266219 1.32 ENST00000394833.2
 SLC39A8
 solute carrier family 39 (zinc transporter), member 8
chr2_+_3642545 1.31 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
 COLEC11
 collectin sub-family member 11
chr2_+_189156721 1.30 ENST00000409927.1
ENST00000409805.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr13_-_46756351 1.29 ENST00000323076.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_116654935 1.28 ENST00000432298.1
ENST00000422922.1
 ST7
 suppression of tumorigenicity 7
chr17_-_72864739 1.28 ENST00000579893.1
ENST00000544854.1
 FDXR
 ferredoxin reductase
chr4_-_159094194 1.27 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
 FAM198B
 family with sequence similarity 198, member B
chr8_-_86290333 1.27 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
 CA1
 carbonic anhydrase I
chr16_+_31539183 1.27 ENST00000302312.4
 AHSP
 alpha hemoglobin stabilizing protein
chr9_-_124989804 1.27 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr12_-_15103621 1.26 ENST00000536592.1
 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
chr12_+_104359614 1.23 ENST00000266775.9
ENST00000544861.1
 TDG
 thymine-DNA glycosylase
chr20_-_30795511 1.23 ENST00000246229.4
 PLAGL2
 pleiomorphic adenoma gene-like 2
chr3_+_148583043 1.22 ENST00000296046.3
 CPA3
 carboxypeptidase A3 (mast cell)
chr8_-_91095099 1.21 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr13_-_46716969 1.21 ENST00000435666.2
 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
chr15_+_51973550 1.21 ENST00000220478.3
 SCG3
 secretogranin III
chr16_-_89043377 1.20 ENST00000436887.2
ENST00000448839.1
ENST00000360302.2
 CBFA2T3
 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_+_12727250 1.20 ENST00000404894.1
 ARL4A
 ADP-ribosylation factor-like 4A
chr1_-_155271213 1.20 ENST00000342741.4
 PKLR
 pyruvate kinase, liver and RBC
chr2_+_189156389 1.16 ENST00000409843.1
 GULP1
 GULP, engulfment adaptor PTB domain containing 1
chr12_+_104359641 1.16 ENST00000537100.1
 TDG
 thymine-DNA glycosylase
chr1_-_39339777 1.14 ENST00000397572.2
 MYCBP
 MYC binding protein
chr19_-_11494975 1.13 ENST00000222139.6
ENST00000592375.2
 EPOR
 erythropoietin receptor
chr21_-_39870339 1.12 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr1_+_43291220 1.11 ENST00000372514.3
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr1_-_24469602 1.11 ENST00000270800.1
 IL22RA1
 interleukin 22 receptor, alpha 1
chrX_+_48380205 1.08 ENST00000446158.1
ENST00000414061.1
 EBP
 emopamil binding protein (sterol isomerase)
chr2_-_219850277 1.01 ENST00000295727.1
 FEV
 FEV (ETS oncogene family)
chr15_-_64126084 1.01 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
 HERC1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr8_-_6420777 1.00 ENST00000415216.1
 ANGPT2
 angiopoietin 2
chr12_+_104359576 0.99 ENST00000392872.3
ENST00000436021.2
 TDG
 thymine-DNA glycosylase
chr1_-_163172625 0.99 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
 RGS5
 regulator of G-protein signaling 5
chr11_-_118213360 0.98 ENST00000529594.1
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr8_-_6420930 0.97 ENST00000325203.5
 ANGPT2
 angiopoietin 2
chr8_-_6420565 0.97 ENST00000338312.6
 ANGPT2
 angiopoietin 2
chr1_-_158656488 0.96 ENST00000368147.4
 SPTA1
 spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_-_16505440 0.96 ENST00000307068.4
 SOSTDC1
 sclerostin domain containing 1
chr17_+_37824411 0.95 ENST00000269582.2
 PNMT
 phenylethanolamine N-methyltransferase
chr8_+_24298597 0.94 ENST00000380789.1
 ADAM7
 ADAM metallopeptidase domain 7
chr22_+_19710468 0.93 ENST00000366425.3
 GP1BB
 glycoprotein Ib (platelet), beta polypeptide
chr7_-_23510086 0.92 ENST00000258729.3
 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
chr11_-_32452357 0.92 ENST00000379079.2
ENST00000530998.1
 WT1
 Wilms tumor 1
chr11_-_66206260 0.91 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
 MRPL11
 mitochondrial ribosomal protein L11
chr15_-_79237433 0.90 ENST00000220166.5
 CTSH
 cathepsin H
chr14_+_102276192 0.89 ENST00000557714.1
 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
chr8_+_40010989 0.87 ENST00000315792.3
 C8orf4
 chromosome 8 open reading frame 4
chr2_+_201994569 0.85 ENST00000457277.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr14_+_102276209 0.85 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
chr12_-_14996355 0.85 ENST00000228936.4
 ART4
 ADP-ribosyltransferase 4 (Dombrock blood group)
chrX_-_11284095 0.83 ENST00000303025.6
ENST00000534860.1
 ARHGAP6
 Rho GTPase activating protein 6
chr4_+_74702214 0.83 ENST00000226317.5
ENST00000515050.1
 CXCL6
 chemokine (C-X-C motif) ligand 6
chr8_+_24298531 0.82 ENST00000175238.6
 ADAM7
 ADAM metallopeptidase domain 7
chr8_-_72268968 0.82 ENST00000388740.3
 EYA1
 eyes absent homolog 1 (Drosophila)
chr12_+_29376592 0.82 ENST00000182377.4
 FAR2
 fatty acyl CoA reductase 2
chr14_+_102276132 0.81 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
chr1_+_12524965 0.81 ENST00000471923.1
 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr8_-_72268889 0.81 ENST00000388742.4
 EYA1
 eyes absent homolog 1 (Drosophila)
chr12_+_29376673 0.81 ENST00000547116.1
 FAR2
 fatty acyl CoA reductase 2
chrX_+_65384182 0.80 ENST00000441993.2
ENST00000419594.1
 HEPH
 hephaestin
chr8_-_6420759 0.78 ENST00000523120.1
 ANGPT2
 angiopoietin 2
chr2_-_228028829 0.78 ENST00000396625.3
ENST00000329662.7
 COL4A4
 collagen, type IV, alpha 4
chr8_-_95449155 0.78 ENST00000481490.2
 FSBP
 fibrinogen silencer binding protein
chr4_+_154387480 0.77 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
 KIAA0922
 KIAA0922
chr2_+_201994208 0.77 ENST00000440180.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr13_+_58206655 0.77 ENST00000377918.3
 PCDH17
 protocadherin 17
chr2_+_33701286 0.77 ENST00000403687.3
 RASGRP3
 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_54872059 0.76 ENST00000371320.3
 SSBP3
 single stranded DNA binding protein 3
chr15_-_43513187 0.75 ENST00000540029.1
ENST00000441366.2
 EPB42
 erythrocyte membrane protein band 4.2
chr21_-_34915147 0.75 ENST00000381831.3
ENST00000381839.3
 GART
 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chrX_+_65384052 0.74 ENST00000336279.5
ENST00000458621.1
 HEPH
 hephaestin
chr14_-_23877474 0.74 ENST00000405093.3
 MYH6
 myosin, heavy chain 6, cardiac muscle, alpha
chr7_+_120629653 0.74 ENST00000450913.2
ENST00000340646.5
 CPED1
 cadherin-like and PC-esterase domain containing 1
chr7_-_20256965 0.73 ENST00000400331.5
ENST00000332878.4
 MACC1
 metastasis associated in colon cancer 1
chr3_+_157827841 0.73 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
 RSRC1
 arginine/serine-rich coiled-coil 1
chr8_-_41655107 0.73 ENST00000347528.4
ENST00000289734.7
ENST00000379758.2
ENST00000396945.1
ENST00000396942.1
ENST00000352337.4
 ANK1
 ankyrin 1, erythrocytic
chr12_+_111843749 0.73 ENST00000341259.2
 SH2B3
 SH2B adaptor protein 3
chrX_+_84258832 0.71 ENST00000373173.2
 APOOL
 apolipoprotein O-like
chr6_-_46889694 0.71 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
 GPR116
 G protein-coupled receptor 116
chr7_-_1980128 0.70 ENST00000437877.1
 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
chr11_-_62609281 0.70 ENST00000525239.1
ENST00000538098.2
 WDR74
 WD repeat domain 74
chr12_-_8218997 0.70 ENST00000307637.4
 C3AR1
 complement component 3a receptor 1
chr3_+_157828152 0.69 ENST00000476899.1
 RSRC1
 arginine/serine-rich coiled-coil 1
chr7_+_112063192 0.68 ENST00000005558.4
 IFRD1
 interferon-related developmental regulator 1
chr7_-_95951334 0.67 ENST00000265631.5
 SLC25A13
 solute carrier family 25 (aspartate/glutamate carrier), member 13
chrX_-_124097620 0.67 ENST00000371130.3
ENST00000422452.2
 TENM1
 teneurin transmembrane protein 1
chr21_-_33975547 0.66 ENST00000431599.1
 C21orf59
 chromosome 21 open reading frame 59
chr2_+_201981527 0.65 ENST00000441224.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr3_+_69812877 0.63 ENST00000457080.1
ENST00000328528.6
 MITF
 microphthalmia-associated transcription factor
chr11_-_64510409 0.62 ENST00000394429.1
ENST00000394428.1
 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_-_71031185 0.62 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr5_+_159848807 0.62 ENST00000352433.5
 PTTG1
 pituitary tumor-transforming 1
chr14_+_29236269 0.61 ENST00000313071.4
 FOXG1
 forkhead box G1
chr6_+_153019069 0.61 ENST00000532295.1
 MYCT1
 myc target 1
chr1_+_199996702 0.60 ENST00000367362.3
 NR5A2
 nuclear receptor subfamily 5, group A, member 2
chr2_+_201981119 0.59 ENST00000395148.2
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr1_+_173793641 0.58 ENST00000361951.4
 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
chr11_-_89223883 0.57 ENST00000528341.1
 NOX4
 NADPH oxidase 4
chr8_+_124194752 0.57 ENST00000318462.6
 FAM83A
 family with sequence similarity 83, member A
chr19_-_4066890 0.56 ENST00000322357.4
 ZBTB7A
 zinc finger and BTB domain containing 7A
chr20_+_43029911 0.56 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
 HNF4A
 hepatocyte nuclear factor 4, alpha
chr6_+_125540951 0.56 ENST00000524679.1
 TPD52L1
 tumor protein D52-like 1
chr10_+_28822417 0.55 ENST00000428935.1
ENST00000420266.1
 WAC
 WW domain containing adaptor with coiled-coil
chr2_-_24149977 0.55 ENST00000238789.5
 ATAD2B
 ATPase family, AAA domain containing 2B
chr11_-_72070206 0.55 ENST00000544382.1
 CLPB
 ClpB caseinolytic peptidase B homolog (E. coli)
chr4_+_110834033 0.54 ENST00000509793.1
ENST00000265171.5
 EGF
 epidermal growth factor
chr3_-_119379427 0.54 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
 POPDC2
 popeye domain containing 2
chr2_-_188312971 0.54 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
 CALCRL
 calcitonin receptor-like
chr6_+_37400974 0.53 ENST00000455891.1
ENST00000373451.4
 CMTR1
 cap methyltransferase 1
chr6_+_89674246 0.53 ENST00000369474.1
 AL079342.1
 Uncharacterized protein; cDNA FLJ27030 fis, clone SLV07741
chr9_-_75567962 0.53 ENST00000297785.3
ENST00000376939.1
 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
chr3_-_58196688 0.52 ENST00000486455.1
 DNASE1L3
 deoxyribonuclease I-like 3
chr16_+_85646763 0.52 ENST00000411612.1
ENST00000253458.7
 GSE1
 Gse1 coiled-coil protein
chr1_+_33283043 0.52 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
 S100PBP
 S100P binding protein
chr14_+_103058948 0.51 ENST00000262241.6
 RCOR1
 REST corepressor 1
chr4_+_74606223 0.50 ENST00000307407.3
ENST00000401931.1
 IL8
 interleukin 8
chr14_-_21566731 0.50 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr1_+_66797687 0.49 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
 PDE4B
 phosphodiesterase 4B, cAMP-specific
chr6_+_153019023 0.48 ENST00000367245.5
ENST00000529453.1
 MYCT1
 myc target 1
chr2_+_103035102 0.48 ENST00000264260.2
 IL18RAP
 interleukin 18 receptor accessory protein
chr5_+_121647764 0.48 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
 SNCAIP
 synuclein, alpha interacting protein
chr6_+_29407083 0.48 ENST00000444197.2
 OR10C1
 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene)
chr3_-_33686743 0.47 ENST00000333778.6
ENST00000539981.1
 CLASP2
 cytoplasmic linker associated protein 2
chr19_+_35739897 0.47 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
 LSR
 lipolysis stimulated lipoprotein receptor
chr12_+_53818855 0.47 ENST00000550839.1
 AMHR2
 anti-Mullerian hormone receptor, type II
chr1_+_173793777 0.46 ENST00000239457.5
 DARS2
 aspartyl-tRNA synthetase 2, mitochondrial
chr19_+_35739782 0.46 ENST00000347609.4
 LSR
 lipolysis stimulated lipoprotein receptor
chr11_-_47374246 0.46 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
 MYBPC3
 myosin binding protein C, cardiac
chr16_+_85646891 0.45 ENST00000393243.1
 GSE1
 Gse1 coiled-coil protein
chr2_+_86668464 0.44 ENST00000409064.1
 KDM3A
 lysine (K)-specific demethylase 3A
chr17_-_60142609 0.44 ENST00000397786.2
 MED13
 mediator complex subunit 13
chr5_-_150603679 0.44 ENST00000355417.2
 CCDC69
 coiled-coil domain containing 69
chr11_+_128563948 0.44 ENST00000534087.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr17_-_40288449 0.44 ENST00000552162.1
ENST00000550504.1
 RAB5C
 RAB5C, member RAS oncogene family
chr1_-_151431647 0.43 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
 POGZ
 pogo transposable element with ZNF domain
chr11_-_47399942 0.43 ENST00000227163.4
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chr14_-_23540747 0.43 ENST00000555566.1
ENST00000338631.6
ENST00000557515.1
ENST00000397341.3
 ACIN1
 apoptotic chromatin condensation inducer 1
chr4_+_186064395 0.43 ENST00000281456.6
 SLC25A4
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr10_+_28822236 0.43 ENST00000347934.4
ENST00000354911.4
 WAC
 WW domain containing adaptor with coiled-coil
chr12_-_71031220 0.43 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 6.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 3.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 4.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 13.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 3.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 10.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 4.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
1.1 3.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
1.1 14.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.8 2.5 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.8 3.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.7 2.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 1.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 3.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 2.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.5 1.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.5 1.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 3.7 GO:0030172 troponin C binding(GO:0030172)
0.4 1.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.4 3.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 9.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 4.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.3 1.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.7 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 2.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 5.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.2 GO:0005499 vitamin D binding(GO:0005499)
0.2 5.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.9 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 2.9 GO:0005518 collagen binding(GO:0005518)
0.2 3.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 1.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.8 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 1.3 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.0 GO:0098821 BMP receptor activity(GO:0098821)
0.2 1.3 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.6 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 4.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.7 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 6.1 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0017018 myosin phosphatase activity(GO:0017018)
0.1 0.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.4 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 15.3 GO:0005178 integrin binding(GO:0005178)
0.1 1.8 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 4.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 2.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 3.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 2.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 1.3 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 2.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0002317 plasma cell differentiation(GO:0002317)
1.1 3.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
1.1 3.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
1.0 14.4 GO:0015671 oxygen transport(GO:0015671)
0.9 3.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.8 3.4 GO:1902544 oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.7 5.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.7 2.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.7 7.0 GO:0001955 blood vessel maturation(GO:0001955)
0.6 2.5 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.6 2.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.6 7.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.5 3.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 1.6 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5 1.6 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.5 3.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.5 1.6 GO:0060584 nitric oxide transport(GO:0030185) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 4.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.5 2.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 1.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 1.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 1.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.3 1.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.3 3.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 1.3 GO:0071461 cellular response to redox state(GO:0071461)
0.3 9.6 GO:0015695 organic cation transport(GO:0015695)
0.3 0.9 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 1.1 GO:0002215 defense response to nematode(GO:0002215)
0.3 2.3 GO:0035799 ureter maturation(GO:0035799)
0.3 0.3 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.2 1.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648) regulation of determination of dorsal identity(GO:2000015)
0.2 2.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.2 0.7 GO:0007518 myoblast fate determination(GO:0007518)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 1.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 0.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 2.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.2 4.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 0.5 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.6 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 3.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.4 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.4 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 1.3 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 2.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.1 0.9 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.7 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.7 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 2.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.5 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 0.8 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.8 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.3 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 2.2 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.3 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.4 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 3.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 3.8 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.0 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.3 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.3 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.2 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 1.2 GO:0002003 angiotensin maturation(GO:0002003)
0.1 0.4 GO:0071504 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0015866 adenine transport(GO:0015853) ADP transport(GO:0015866)
0.1 0.3 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 1.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.1 GO:0090346 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.5 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.6 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.1 0.2 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
0.1 0.5 GO:0001505 regulation of neurotransmitter levels(GO:0001505)
0.1 0.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.1 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.1 0.5 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 3.7 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0032383 dolichol metabolic process(GO:0019348) regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 1.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:2000291 myoblast proliferation(GO:0051450) regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.2 GO:0051105 regulation of DNA ligation(GO:0051105)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 1.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.8 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0019079 viral genome replication(GO:0019079)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.2 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 2.4 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 5.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0001764 neuron migration(GO:0001764)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.4 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0045143 homologous chromosome segregation(GO:0045143)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 2.3 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.5 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.6 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.4 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.6 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.3 GO:0046349 N-acetylglucosamine metabolic process(GO:0006044) amino sugar biosynthetic process(GO:0046349)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.9 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.8 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 3.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.5 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 1.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 4.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 6.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 4.2 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 13.9 GO:0005833 hemoglobin complex(GO:0005833)
0.6 3.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 3.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.4 1.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 4.6 GO:0097342 ripoptosome(GO:0097342)
0.2 3.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.6 GO:0030061 mitochondrial crista(GO:0030061)
0.2 5.0 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 2.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 4.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 3.1 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 3.1 GO:0042588 zymogen granule(GO:0042588)
0.1 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 1.0 GO:0032437 cuticular plate(GO:0032437)
0.1 5.2 GO:0030027 lamellipodium(GO:0030027)
0.1 0.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 2.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 9.9 GO:0016605 PML body(GO:0016605)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.9 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 1.0 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 5.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 3.5 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)
0.0 19.3 GO:0005887 integral component of plasma membrane(GO:0005887)