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ENCODE cell lines, expression (Ernst 2011)

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Results for GATA2

Z-value: 1.43

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Transcription factors associated with GATA2

Gene Symbol Gene ID Gene Info
ENSG00000179348.7 GATA2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA2hg19_v2_chr3_-_128206759_128206781-0.495.3e-02Click!

Activity profile of GATA2 motif

Sorted Z-values of GATA2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_149095652 4.51 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr12_+_75874580 3.50 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr7_+_134430212 3.33 ENST00000436461.2
CALD1
caldesmon 1
chr12_+_75874460 3.26 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr9_-_14180778 3.17 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr16_+_55512742 2.89 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr3_-_149688655 2.63 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2
profilin 2
chr2_-_216257849 2.52 ENST00000456923.1
FN1
fibronectin 1
chr11_+_114168085 2.47 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chr7_+_134528635 2.27 ENST00000445569.2
CALD1
caldesmon 1
chr11_+_117073850 2.19 ENST00000529622.1
TAGLN
transgelin
chr2_-_175711133 2.17 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr12_-_91546926 2.10 ENST00000550758.1
DCN
decorin
chrX_-_38080077 2.10 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr7_-_94285472 2.09 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr7_-_107642348 2.08 ENST00000393561.1
LAMB1
laminin, beta 1
chr7_-_94285511 2.05 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr10_-_90712520 2.05 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_+_75874984 2.00 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr1_+_180165672 1.97 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr2_+_192109911 1.93 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr9_+_116263639 1.90 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr11_+_35201826 1.88 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr1_-_79472365 1.80 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr1_+_81771806 1.80 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr9_+_116263778 1.78 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr5_+_102201509 1.74 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_-_145878954 1.69 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr4_-_143226979 1.67 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_114522049 1.63 ENST00000369551.1
ENST00000320334.4
OLFML3
olfactomedin-like 3
chr18_-_21891460 1.58 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr5_+_140772381 1.57 ENST00000398604.2
PCDHGA8
protocadherin gamma subfamily A, 8
chr4_+_88928777 1.50 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr3_+_154797877 1.43 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr10_-_15413035 1.42 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr12_+_66217911 1.38 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr5_+_148737562 1.34 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr2_-_190044480 1.33 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr1_+_183774240 1.31 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_-_91573132 1.30 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr2_-_24307162 1.30 ENST00000413037.1
ENST00000407482.1
TP53I3
tumor protein p53 inducible protein 3
chr13_-_96296944 1.28 ENST00000361396.2
ENST00000376829.2
DZIP1
DAZ interacting zinc finger protein 1
chr5_+_102201430 1.28 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr6_+_7727030 1.27 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr12_+_16109519 1.25 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr3_+_159570722 1.25 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr12_-_91573249 1.24 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr7_-_27169801 1.23 ENST00000511914.1
HOXA4
homeobox A4
chr14_-_74959978 1.23 ENST00000541064.1
NPC2
Niemann-Pick disease, type C2
chr11_+_69455855 1.19 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr1_+_84630053 1.17 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_-_10851762 1.16 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr14_-_74959994 1.14 ENST00000238633.2
ENST00000434013.2
NPC2
Niemann-Pick disease, type C2
chr8_-_67525473 1.12 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr7_-_120498357 1.08 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr9_-_13175823 1.08 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr6_-_134495992 1.08 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr13_+_102142296 1.07 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_15165854 1.05 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr3_-_49170405 1.04 ENST00000305544.4
ENST00000494831.1
LAMB2
laminin, beta 2 (laminin S)
chr1_-_150780757 1.04 ENST00000271651.3
CTSK
cathepsin K
chr11_-_125366089 1.04 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr9_-_79307096 1.01 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr7_+_55177416 1.01 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr12_-_124457257 1.00 ENST00000545891.1
CCDC92
coiled-coil domain containing 92
chr3_-_49170522 0.99 ENST00000418109.1
LAMB2
laminin, beta 2 (laminin S)
chr7_+_94023873 0.99 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr2_-_235405168 0.99 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr5_+_34656331 0.99 ENST00000265109.3
RAI14
retinoic acid induced 14
chr22_+_38609538 0.98 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr5_+_140753444 0.98 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr6_+_17393888 0.97 ENST00000493172.1
ENST00000465994.1
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chrX_-_13835147 0.97 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr5_+_148521136 0.97 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr4_-_186733363 0.94 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr9_-_13165457 0.94 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr11_-_89224638 0.94 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr2_+_201450591 0.93 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr8_-_27468842 0.93 ENST00000523500.1
CLU
clusterin
chr8_-_27468945 0.92 ENST00000405140.3
CLU
clusterin
chr4_+_74735102 0.92 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_-_74960030 0.92 ENST00000553490.1
ENST00000557510.1
NPC2
Niemann-Pick disease, type C2
chr17_-_48278983 0.92 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr6_-_80657292 0.92 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr5_+_125758813 0.90 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr1_-_163172625 0.89 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5
regulator of G-protein signaling 5
chr4_+_146403912 0.88 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr1_+_150245177 0.87 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr12_-_91572278 0.87 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr3_+_100211412 0.86 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A
transmembrane protein 45A
chr5_+_125758865 0.86 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr10_-_116286563 0.86 ENST00000369253.2
ABLIM1
actin binding LIM protein 1
chr3_+_136537911 0.85 ENST00000393079.3
SLC35G2
solute carrier family 35, member G2
chr3_+_136537816 0.85 ENST00000446465.2
SLC35G2
solute carrier family 35, member G2
chr8_-_18666360 0.84 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chrX_-_13956737 0.84 ENST00000454189.2
GPM6B
glycoprotein M6B
chr13_-_33780133 0.83 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_-_117186946 0.82 ENST00000313005.6
ENST00000528053.1
BACE1
beta-site APP-cleaving enzyme 1
chr3_-_79068594 0.81 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_6576895 0.81 ENST00000285599.3
ENST00000504248.1
ENST00000505907.1
MAN2B2
mannosidase, alpha, class 2B, member 2
chr10_+_13141585 0.80 ENST00000378764.2
OPTN
optineurin
chr8_-_93029865 0.79 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_110933611 0.79 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr8_+_70404996 0.78 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr21_+_35014783 0.77 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
ITSN1
intersectin 1 (SH3 domain protein)
chr3_+_187930719 0.77 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_-_167276033 0.76 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_-_41216619 0.76 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr7_-_38671098 0.75 ENST00000356264.2
AMPH
amphiphysin
chr8_-_6420930 0.75 ENST00000325203.5
ANGPT2
angiopoietin 2
chr4_-_143227088 0.74 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr1_+_84630645 0.74 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr16_+_1583567 0.73 ENST00000566264.1
TMEM204
transmembrane protein 204
chr14_-_70883708 0.72 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr3_-_8811288 0.72 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr8_-_18744528 0.72 ENST00000523619.1
PSD3
pleckstrin and Sec7 domain containing 3
chr11_+_33563821 0.72 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr8_-_49834299 0.72 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr19_+_18496957 0.71 ENST00000252809.3
GDF15
growth differentiation factor 15
chr15_-_23932437 0.71 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr1_+_150245099 0.71 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr1_-_43919573 0.71 ENST00000372432.1
ENST00000372425.4
ENST00000583037.1
HYI
hydroxypyruvate isomerase (putative)
chr15_+_83776324 0.70 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1
transmembrane 6 superfamily member 1
chr8_+_74903580 0.70 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr12_-_49582978 0.69 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr2_+_201170770 0.68 ENST00000409988.3
ENST00000409385.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr7_-_38670957 0.67 ENST00000325590.5
ENST00000428293.2
AMPH
amphiphysin
chr10_-_116444371 0.65 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr6_-_75994536 0.65 ENST00000475111.2
ENST00000230461.6
TMEM30A
transmembrane protein 30A
chr4_-_70626314 0.64 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr3_-_66551397 0.64 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr12_+_79439405 0.63 ENST00000552744.1
SYT1
synaptotagmin I
chr11_+_124609823 0.63 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr2_-_190927447 0.62 ENST00000260950.4
MSTN
myostatin
chr17_-_7145475 0.62 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr1_-_169703203 0.61 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr10_-_79397391 0.60 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_126237554 0.60 ENST00000394329.3
FAT4
FAT atypical cadherin 4
chr3_-_73673991 0.60 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chr6_-_152639479 0.60 ENST00000356820.4
SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_-_11685345 0.59 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chrX_-_108976521 0.59 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr3_-_189840223 0.58 ENST00000427335.2
LEPREL1
leprecan-like 1
chr18_-_53303123 0.58 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr12_+_79258547 0.57 ENST00000457153.2
SYT1
synaptotagmin I
chr1_+_101702417 0.57 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr11_-_111781554 0.57 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr12_+_3000073 0.57 ENST00000397132.2
TULP3
tubby like protein 3
chr3_-_47950745 0.56 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr13_-_23949671 0.56 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr4_-_70361579 0.56 ENST00000512583.1
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr3_-_50360192 0.56 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2
hyaluronoglucosaminidase 2
chr8_+_54764346 0.56 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr4_-_70361615 0.55 ENST00000305107.6
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr4_+_154074217 0.54 ENST00000437508.2
TRIM2
tripartite motif containing 2
chr9_+_116267536 0.54 ENST00000374136.1
RGS3
regulator of G-protein signaling 3
chr11_-_111794446 0.54 ENST00000527950.1
CRYAB
crystallin, alpha B
chrX_+_149531524 0.54 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr19_-_51466681 0.52 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chr1_-_153517473 0.52 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr18_-_52989217 0.52 ENST00000570287.2
TCF4
transcription factor 4
chr11_+_124609742 0.52 ENST00000284292.6
NRGN
neurogranin (protein kinase C substrate, RC3)
chr10_+_5135981 0.52 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr15_+_80733570 0.51 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr12_-_9268707 0.51 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr7_-_86849025 0.50 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr12_-_8815299 0.50 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr4_+_156680153 0.49 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr10_+_8096631 0.49 ENST00000379328.3
GATA3
GATA binding protein 3
chr3_+_107241783 0.49 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
BBX
bobby sox homolog (Drosophila)
chr15_+_63569785 0.49 ENST00000380343.4
ENST00000560353.1
APH1B
APH1B gamma secretase subunit
chr16_+_15528332 0.49 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr15_+_71184931 0.49 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr1_-_9811600 0.49 ENST00000435891.1
CLSTN1
calsyntenin 1
chr14_+_21156915 0.47 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_-_208030647 0.47 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_-_101690650 0.47 ENST00000543621.1
DNMBP
dynamin binding protein
chr1_+_78511586 0.47 ENST00000370759.3
GIPC2
GIPC PDZ domain containing family, member 2
chr8_+_22462532 0.47 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chrX_-_68385354 0.46 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr15_-_52587945 0.46 ENST00000443683.2
ENST00000558479.1
ENST00000261839.7
MYO5C
myosin VC
chr7_-_2883928 0.46 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr11_-_111782484 0.46 ENST00000533971.1
CRYAB
crystallin, alpha B
chr18_-_52989525 0.46 ENST00000457482.3
TCF4
transcription factor 4
chr16_+_14802801 0.45 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr11_-_65655906 0.45 ENST00000533045.1
ENST00000338369.2
ENST00000357519.4
FIBP
fibroblast growth factor (acidic) intracellular binding protein
chr20_+_34802295 0.45 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr6_+_80816342 0.44 ENST00000369760.4
ENST00000356489.5
ENST00000320393.6
BCKDHB
branched chain keto acid dehydrogenase E1, beta polypeptide
chr10_-_79397316 0.44 ENST00000372421.5
ENST00000457953.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_+_52535878 0.43 ENST00000211314.4
TMEM14A
transmembrane protein 14A
chrX_+_80457442 0.43 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr4_+_74275057 0.43 ENST00000511370.1
ALB
albumin
chr20_-_20033052 0.42 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr2_+_201997595 0.42 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr11_+_57520715 0.42 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr16_+_58533951 0.41 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr12_-_8815215 0.41 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr22_+_39916558 0.40 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr2_-_179672142 0.40 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr7_-_86974767 0.40 ENST00000610086.1
TP53TG1
TP53 target 1 (non-protein coding)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.6 2.5 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.6 1.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5 2.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.5 2.4 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.5 1.4 GO:0035501 MH1 domain binding(GO:0035501)
0.4 1.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.4 1.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 1.3 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.4 1.5 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.3 0.8 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.3 0.8 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 1.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.2 0.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 5.4 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.5 GO:0047718 enone reductase activity(GO:0035671) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 10.5 GO:0005518 collagen binding(GO:0005518)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.9 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.4 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.1 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0046625 sphingolipid binding(GO:0046625)
0.1 1.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.2 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 2.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 4.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 1.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 2.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005607 laminin-2 complex(GO:0005607)
0.7 2.0 GO:0005608 laminin-3 complex(GO:0005608)
0.5 4.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 2.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 5.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 5.6 GO:0030478 actin cap(GO:0030478)
0.3 1.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.3 0.8 GO:0044609 DBIRD complex(GO:0044609)
0.3 1.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 1.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.2 2.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 1.0 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.9 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 9.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.0 GO:0043218 compact myelin(GO:0043218)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.3 GO:0097342 ripoptosome(GO:0097342)
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 1.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.3 GO:0071546 pi-body(GO:0071546)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 3.3 GO:0043195 terminal bouton(GO:0043195)
0.0 3.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 4.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.7 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 3.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.6 GO:0044449 contractile fiber part(GO:0044449)
0.0 0.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.0 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.7 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 10.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 2.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 3.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
1.0 3.8 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.8 2.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.8 3.0 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.6 1.7 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 1.5 GO:0031587 detection of endogenous stimulus(GO:0009726) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.5 1.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 0.9 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.5 1.4 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.5 5.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.5 3.2 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 1.3 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.4 2.0 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.4 1.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.4 1.9 GO:0097338 response to clozapine(GO:0097338)
0.4 1.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.4 3.6 GO:0070141 response to UV-A(GO:0070141)
0.3 1.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 2.0 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.3 1.3 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.3 1.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.3 1.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.9 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 0.6 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.3 2.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 2.1 GO:0001845 phagolysosome assembly(GO:0001845) negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 1.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.5 GO:2000683 regulation of cellular response to X-ray(GO:2000683)
0.2 0.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 2.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 0.6 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 2.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.2 0.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 1.0 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.7 GO:0034465 response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.2 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.6 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.5 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.1 0.1 GO:0051081 mitotic nuclear envelope disassembly(GO:0007077) membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 4.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.3 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.8 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.2 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 2.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 1.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.1 0.4 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1 1.2 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.1 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 1.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.2 GO:0021558 trochlear nerve development(GO:0021558)
0.1 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.2 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.1 0.2 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.1 2.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0090260 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.2 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 1.0 GO:0032060 bleb assembly(GO:0032060)
0.1 0.2 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.1 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.0 0.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 1.1 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.1 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.0 1.0 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:1904435 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.9 GO:1902624 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.9 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 2.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.7 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.7 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 2.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.2 GO:0061025 membrane fusion(GO:0061025)
0.0 1.0 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 0.7 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.2 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 1.8 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.0 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.9 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:1990440 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 3.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 5.7 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.6 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0044241 lipid digestion(GO:0044241)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 7.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 4.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 3.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 8.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 3.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse