ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
GATA5 Links Ensembl NCBI GeneCards UniProt	ENSG00000130700.6	GATA5

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Promoter	Score	Transcript	Gene	Gene Info
chr1_-_160681593	3.23	ENST00000368045.3 ENST00000368046.3	CD48	CD48 molecule
chr13_-_46756351	3.13	ENST00000323076.2	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr9_-_6645628	3.13	ENST00000321612.6	GLDC	glycine dehydrogenase (decarboxylating)
chr4_-_110723335	2.69	ENST00000394634.2	CFI	complement factor I
chr7_+_26332645	2.63	ENST00000396376.1	SNX10	sorting nexin 10
chr4_-_110723134	2.52	ENST00000510800.1 ENST00000512148.1	CFI	complement factor I
chr4_-_110723194	2.52	ENST00000394635.3	CFI	complement factor I
chr6_-_32557610	2.45	ENST00000360004.5	HLA-DRB1	major histocompatibility complex, class II, DR beta 1
chr6_+_32709119	2.42	ENST00000374940.3	HLA-DQA2	major histocompatibility complex, class II, DQ alpha 2
chr17_+_53344945	2.36	ENST00000575345.1	HLF	hepatic leukemia factor
chr10_+_7745232	2.36	ENST00000358415.4	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745303	2.35	ENST00000429820.1 ENST00000379587.4	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr11_+_121461097	2.05	ENST00000527934.1	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr10_-_98031265	2.01	ENST00000224337.5 ENST00000371176.2	BLNK	B-cell linker
chr2_+_143635067	1.71	ENST00000264170.4	KYNU	kynureninase
chr19_+_35820064	1.70	ENST00000341773.6 ENST00000600131.1 ENST00000270311.6 ENST00000595780.1 ENST00000597916.1 ENST00000593867.1 ENST00000600424.1 ENST00000599811.1 ENST00000536635.2 ENST00000085219.5 ENST00000544992.2 ENST00000419549.2	CD22	CD22 molecule
chr4_+_155484155	1.60	ENST00000509493.1	FGB	fibrinogen beta chain
chr22_-_29107919	1.47	ENST00000434810.1 ENST00000456369.1	CHEK2	checkpoint kinase 2
chr8_+_28196157	1.47	ENST00000522209.1	PNOC	prepronociceptin
chr6_+_33043703	1.43	ENST00000418931.2 ENST00000535465.1	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr9_-_35650900	1.41	ENST00000259608.3	SIT1	signaling threshold regulating transmembrane adaptor 1
chr3_+_178276488	1.33	ENST00000432997.1 ENST00000455865.1	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_+_174844645	1.25	ENST00000486220.1	RABGAP1L	RAB GTPase activating protein 1-like
chr15_-_20193370	1.17	ENST00000558565.2	IGHV3OR15-7	immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr12_-_9268707	1.16	ENST00000318602.7	A2M	alpha-2-macroglobulin
chr6_+_31916733	1.15	ENST00000483004.1	CFB	complement factor B
chr8_+_86099884	1.12	ENST00000517476.1 ENST00000521429.1	E2F5	E2F transcription factor 5, p130-binding
chr19_-_10450328	1.08	ENST00000160262.5	ICAM3	intercellular adhesion molecule 3
chr8_+_40010989	1.04	ENST00000315792.3	C8orf4	chromosome 8 open reading frame 4
chr6_-_154677900	1.03	ENST00000265198.4 ENST00000520261.1	IPCEF1	interaction protein for cytohesin exchange factors 1
chr11_+_128563652	1.01	ENST00000527786.2	FLI1	Fli-1 proto-oncogene, ETS transcription factor
chr4_+_155484103	1.00	ENST00000302068.4	FGB	fibrinogen beta chain
chr1_+_207277590	0.99	ENST00000367070.3	C4BPA	complement component 4 binding protein, alpha
chr12_+_54892550	0.95	ENST00000545638.2	NCKAP1L	NCK-associated protein 1-like
chr2_+_102615416	0.90	ENST00000393414.2	IL1R2	interleukin 1 receptor, type II
chr6_-_32908765	0.84	ENST00000416244.2	HLA-DMB	major histocompatibility complex, class II, DM beta
chr3_-_197300194	0.77	ENST00000358186.2 ENST00000431056.1	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr11_-_33891362	0.76	ENST00000395833.3	LMO2	LIM domain only 2 (rhombotin-like 1)
chr2_+_69201705	0.76	ENST00000377938.2	GKN1	gastrokine 1
chrX_+_30261847	0.74	ENST00000378981.3 ENST00000397550.1	MAGEB1	melanoma antigen family B, 1
chr8_+_117778736	0.70	ENST00000309822.2 ENST00000357148.3 ENST00000517814.1 ENST00000517820.1	UTP23	UTP23, small subunit (SSU) processome component, homolog (yeast)
chr18_+_13611763	0.70	ENST00000585931.1	LDLRAD4	low density lipoprotein receptor class A domain containing 4
chr14_+_39735411	0.69	ENST00000603904.1	RP11-407N17.3	cTAGE family member 5 isoform 4
chr1_+_156123318	0.68	ENST00000368285.3	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_57320437	0.67	ENST00000361249.3	C8A	complement component 8, alpha polypeptide
chrX_+_52235228	0.67	ENST00000518075.1	XAGE1B	X antigen family, member 1B
chr13_-_99910673	0.66	ENST00000397473.2 ENST00000397470.2	GPR18	G protein-coupled receptor 18
chr11_+_101785727	0.66	ENST00000263468.8	KIAA1377	KIAA1377
chr15_-_34628951	0.65	ENST00000397707.2 ENST00000560611.1	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6
chr1_+_79115503	0.64	ENST00000370747.4 ENST00000438486.1 ENST00000545124.1	IFI44	interferon-induced protein 44
chr6_-_43027105	0.64	ENST00000230413.5 ENST00000487429.1 ENST00000489623.1 ENST00000468957.1	MRPL2	mitochondrial ribosomal protein L2
chr3_-_178969403	0.62	ENST00000314235.5 ENST00000392685.2	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr7_-_123197733	0.62	ENST00000470123.1 ENST00000471770.1	NDUFA5	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr10_+_35484053	0.58	ENST00000487763.1 ENST00000473940.1 ENST00000488328.1 ENST00000356917.5	CREM	cAMP responsive element modulator
chr11_+_124824000	0.57	ENST00000529051.1 ENST00000344762.5	CCDC15	coiled-coil domain containing 15
chr6_-_86099898	0.56	ENST00000455071.1	RP11-30P6.6	RP11-30P6.6
chr2_+_201997595	0.53	ENST00000470178.2	CFLAR	CASP8 and FADD-like apoptosis regulator
chr3_+_184080387	0.53	ENST00000455712.1	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr5_+_140261703	0.51	ENST00000409494.1 ENST00000289272.2	PCDHA13	protocadherin alpha 13
chr3_-_182817297	0.50	ENST00000539926.1 ENST00000476176.1	MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)
chr1_+_150954493	0.50	ENST00000368947.4	ANXA9	annexin A9
chr1_-_11918988	0.50	ENST00000376468.3	NPPB	natriuretic peptide B
chr6_-_53409890	0.49	ENST00000229416.6	GCLC	glutamate-cysteine ligase, catalytic subunit
chr6_-_55739542	0.48	ENST00000446683.2	BMP5	bone morphogenetic protein 5
chr2_-_191115229	0.46	ENST00000409820.2 ENST00000410045.1	HIBCH	3-hydroxyisobutyryl-CoA hydrolase
chr2_+_201997492	0.45	ENST00000494258.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr22_+_23412479	0.44	ENST00000248996.4	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr1_+_10292308	0.43	ENST00000377081.1	KIF1B	kinesin family member 1B
chr6_-_135271260	0.42	ENST00000265605.2	ALDH8A1	aldehyde dehydrogenase 8 family, member A1
chr1_-_150669500	0.42	ENST00000271732.3	GOLPH3L	golgi phosphoprotein 3-like
chr11_-_72070206	0.40	ENST00000544382.1	CLPB	ClpB caseinolytic peptidase B homolog (E. coli)
chr3_-_137851220	0.37	ENST00000236709.3	A4GNT	alpha-1,4-N-acetylglucosaminyltransferase
chr1_+_150229554	0.37	ENST00000369111.4	CA14	carbonic anhydrase XIV
chr14_+_61995722	0.35	ENST00000556347.1	RP11-47I22.4	RP11-47I22.4
chr19_-_52133588	0.34	ENST00000570106.2	SIGLEC5	sialic acid binding Ig-like lectin 5
chr6_-_133079022	0.34	ENST00000525289.1 ENST00000326499.6	VNN2	vanin 2
chr16_+_77224732	0.34	ENST00000569610.1 ENST00000248248.3 ENST00000567291.1 ENST00000320859.6 ENST00000563612.1 ENST00000563279.1	MON1B	MON1 secretory trafficking family member B
chr16_-_33647696	0.33	ENST00000558425.1 ENST00000569103.2	RP11-812E19.9	Uncharacterized protein
chr3_-_178984759	0.33	ENST00000349697.2 ENST00000497599.1	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr1_-_158656488	0.32	ENST00000368147.4	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr6_-_135271219	0.31	ENST00000367847.2 ENST00000367845.2	ALDH8A1	aldehyde dehydrogenase 8 family, member A1
chr4_+_110834033	0.30	ENST00000509793.1 ENST00000265171.5	EGF	epidermal growth factor
chr6_+_118869452	0.29	ENST00000357525.5	PLN	phospholamban
chr5_-_75919253	0.29	ENST00000296641.4	F2RL2	coagulation factor II (thrombin) receptor-like 2
chr5_-_75919217	0.29	ENST00000504899.1	F2RL2	coagulation factor II (thrombin) receptor-like 2
chr7_+_136553370	0.28	ENST00000445907.2	CHRM2	cholinergic receptor, muscarinic 2
chr4_+_175204818	0.28	ENST00000503780.1	CEP44	centrosomal protein 44kDa
chr16_+_31366536	0.28	ENST00000562522.1	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_-_109605663	0.28	ENST00000409271.1 ENST00000258443.2 ENST00000376651.1	EDAR	ectodysplasin A receptor
chr17_-_41277467	0.27	ENST00000494123.1 ENST00000346315.3 ENST00000309486.4 ENST00000468300.1 ENST00000354071.3 ENST00000352993.3 ENST00000471181.2	BRCA1	breast cancer 1, early onset
chr8_-_91095099	0.26	ENST00000265431.3	CALB1	calbindin 1, 28kDa
chr9_+_106856831	0.26	ENST00000303219.8 ENST00000374787.3	SMC2	structural maintenance of chromosomes 2
chr3_+_108541545	0.25	ENST00000295756.6	TRAT1	T cell receptor associated transmembrane adaptor 1
chr9_-_21166659	0.25	ENST00000380225.1	IFNA21	interferon, alpha 21
chr3_+_141144954	0.25	ENST00000441582.2 ENST00000321464.5	ZBTB38	zinc finger and BTB domain containing 38
chr1_-_182921119	0.25	ENST00000423786.1	SHCBP1L	SHC SH2-domain binding protein 1-like
chr10_+_15085936	0.25	ENST00000378217.3	OLAH	oleoyl-ACP hydrolase
chr4_-_100356551	0.24	ENST00000209665.4	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr10_+_62538089	0.24	ENST00000519078.2 ENST00000395284.3 ENST00000316629.4	CDK1	cyclin-dependent kinase 1
chr17_-_61996136	0.23	ENST00000342364.4	GH1	growth hormone 1
chr3_+_108541608	0.23	ENST00000426646.1	TRAT1	T cell receptor associated transmembrane adaptor 1
chr19_-_14952689	0.23	ENST00000248058.1	OR7A10	olfactory receptor, family 7, subfamily A, member 10
chrX_+_100645812	0.22	ENST00000427805.2 ENST00000553110.3 ENST00000392994.3 ENST00000409338.1 ENST00000409170.3	RPL36A RPL36A-HNRNPH2	ribosomal protein L36a RPL36A-HNRNPH2 readthrough
chr1_+_62439037	0.22	ENST00000545929.1	INADL	InaD-like (Drosophila)
chr12_+_101988627	0.21	ENST00000547405.1 ENST00000452455.2 ENST00000441232.1 ENST00000360610.2 ENST00000392934.3 ENST00000547509.1 ENST00000361685.2 ENST00000549145.1 ENST00000553190.1	MYBPC1	myosin binding protein C, slow type
chr16_-_28503357	0.20	ENST00000333496.9 ENST00000561505.1 ENST00000567963.1 ENST00000354630.5 ENST00000355477.5 ENST00000357076.5 ENST00000565688.1 ENST00000359984.7	CLN3	ceroid-lipofuscinosis, neuronal 3
chr1_-_89357179	0.20	ENST00000448623.1 ENST00000418217.1 ENST00000370500.5	GTF2B	general transcription factor IIB
chr15_+_99791567	0.20	ENST00000558879.1 ENST00000301981.3 ENST00000422500.2 ENST00000447360.2 ENST00000442993.2	LRRC28	leucine rich repeat containing 28
chr6_-_33290580	0.20	ENST00000446511.1 ENST00000446403.1 ENST00000414083.2 ENST00000266000.6 ENST00000374542.5	DAXX	death-domain associated protein
chr17_-_61996160	0.20	ENST00000458650.2 ENST00000351388.4 ENST00000323322.5	GH1	growth hormone 1
chrX_+_46771711	0.19	ENST00000424392.1 ENST00000397189.1	PHF16	jade family PHD finger 3
chr14_+_21785693	0.19	ENST00000382933.4 ENST00000557351.1	RPGRIP1	retinitis pigmentosa GTPase regulator interacting protein 1
chr5_-_34916871	0.19	ENST00000382038.2	RAD1	RAD1 homolog (S. pombe)
chr12_-_45270151	0.19	ENST00000429094.2	NELL2	NEL-like 2 (chicken)
chr1_+_171454639	0.19	ENST00000392078.3 ENST00000426496.2	PRRC2C	proline-rich coiled-coil 2C
chr12_-_45270077	0.19	ENST00000551601.1 ENST00000549027.1 ENST00000452445.2	NELL2	NEL-like 2 (chicken)
chr1_+_115572415	0.18	ENST00000256592.1	TSHB	thyroid stimulating hormone, beta
chr17_-_72772462	0.18	ENST00000582870.1 ENST00000581136.1 ENST00000357814.3 ENST00000579218.1 ENST00000583476.1 ENST00000580301.1 ENST00000583757.1 ENST00000582524.1	NAT9	N-acetyltransferase 9 (GCN5-related, putative)
chr14_+_76618242	0.16	ENST00000557542.1 ENST00000557263.1 ENST00000557207.1 ENST00000312858.5 ENST00000261530.7	GPATCH2L	G patch domain containing 2-like
chr2_-_40006289	0.15	ENST00000260619.6 ENST00000454352.2	THUMPD2	THUMP domain containing 2
chr10_+_15085895	0.14	ENST00000378228.3	OLAH	oleoyl-ACP hydrolase
chr12_-_68619586	0.14	ENST00000229134.4	IL26	interleukin 26
chr6_-_29395509	0.13	ENST00000377147.2	OR11A1	olfactory receptor, family 11, subfamily A, member 1
chr1_-_157014865	0.12	ENST00000361409.2	ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11
chr16_+_31366455	0.11	ENST00000268296.4	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_-_45269430	0.11	ENST00000395487.2	NELL2	NEL-like 2 (chicken)
chr17_-_61996192	0.11	ENST00000392824.4	CSHL1	chorionic somatomammotropin hormone-like 1
chr6_-_90529418	0.10	ENST00000439638.1 ENST00000369393.3 ENST00000428876.1	MDN1	MDN1, midasin homolog (yeast)
chr18_+_13612613	0.10	ENST00000586765.1	LDLRAD4	low density lipoprotein receptor class A domain containing 4
chr6_+_46761118	0.10	ENST00000230588.4	MEP1A	meprin A, alpha (PABA peptide hydrolase)
chr9_-_123239632	0.10	ENST00000416449.1	CDK5RAP2	CDK5 regulatory subunit associated protein 2
chr15_+_66874502	0.10	ENST00000558797.1	RP11-321F6.1	HCG2003567; Uncharacterized protein
chr14_-_24553834	0.10	ENST00000397002.2	NRL	neural retina leucine zipper
chr2_-_49381572	0.10	ENST00000454032.1 ENST00000304421.4	FSHR	follicle stimulating hormone receptor
chr11_+_30252549	0.10	ENST00000254122.3 ENST00000417547.1	FSHB	follicle stimulating hormone, beta polypeptide
chr16_+_31539183	0.09	ENST00000302312.4	AHSP	alpha hemoglobin stabilizing protein
chr2_+_201997676	0.08	ENST00000462763.1 ENST00000479953.2	CFLAR	CASP8 and FADD-like apoptosis regulator
chr1_-_27226928	0.08	ENST00000361720.5	GPATCH3	G patch domain containing 3
chr4_-_47983519	0.08	ENST00000358519.4 ENST00000544810.1 ENST00000402813.3	CNGA1	cyclic nucleotide gated channel alpha 1
chr15_+_100106155	0.07	ENST00000557785.1 ENST00000558049.1 ENST00000449277.2	MEF2A	myocyte enhancer factor 2A
chr20_+_43211149	0.06	ENST00000372886.1	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr6_-_24936170	0.06	ENST00000538035.1	FAM65B	family with sequence similarity 65, member B
chr19_-_14992264	0.06	ENST00000327462.2	OR7A17	olfactory receptor, family 7, subfamily A, member 17
chr4_+_71570430	0.06	ENST00000417478.2	RUFY3	RUN and FYVE domain containing 3
chr12_+_62860581	0.05	ENST00000393632.2 ENST00000393630.3 ENST00000280379.6 ENST00000546600.1 ENST00000552738.1 ENST00000393629.2 ENST00000552115.1	MON2	MON2 homolog (S. cerevisiae)
chr2_-_49381646	0.05	ENST00000346173.3 ENST00000406846.2	FSHR	follicle stimulating hormone receptor
chr6_+_126102292	0.05	ENST00000368357.3	NCOA7	nuclear receptor coactivator 7
chr1_-_203274418	0.05	ENST00000457348.1	RP11-134P9.1	long intergenic non-protein coding RNA 1136
chr18_-_3874752	0.03	ENST00000534970.1	DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr10_-_114206649	0.03	ENST00000369404.3 ENST00000369405.3	ZDHHC6	zinc finger, DHHC-type containing 6
chr9_-_215744	0.03	ENST00000382387.2	C9orf66	chromosome 9 open reading frame 66
chr12_+_20968608	0.03	ENST00000381541.3 ENST00000540229.1 ENST00000553473.1 ENST00000554957.1	LST3 SLCO1B3 SLCO1B7	Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein solute carrier organic anion transporter family, member 1B3 solute carrier organic anion transporter family, member 1B7 (non-functional)
chr10_+_60028818	0.02	ENST00000333926.5	CISD1	CDGSH iron sulfur domain 1
chr3_+_155860751	0.02	ENST00000471742.1	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_-_54582655	0.02	ENST00000504338.1 ENST00000514685.1 ENST00000504797.1 ENST00000513838.1 ENST00000505128.1 ENST00000337581.3 ENST00000503306.1 ENST00000243112.5 ENST00000514196.1 ENST00000506169.1 ENST00000507904.1 ENST00000508394.2	SMUG1	single-strand-selective monofunctional uracil-DNA glycosylase 1
chr9_-_70490107	0.01	ENST00000377395.4 ENST00000429800.2 ENST00000430059.2 ENST00000377384.1 ENST00000382405.3	CBWD5	COBW domain containing 5
chr12_+_57881740	0.00	ENST00000262027.5 ENST00000315473.5	MARS	methionyl-tRNA synthetase
chr11_+_118754475	0.00	ENST00000292174.4	CXCR5	chemokine (C-X-C motif) receptor 5

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4	1.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.3	0.8	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	3.1	GO:0016594	glycine binding(GO:0016594)
0.2	1.5	GO:0001515	opioid peptide activity(GO:0001515)
0.2	0.9	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2	2.4	GO:0032395	MHC class II receptor activity(GO:0032395)
0.1	0.4	GO:0005148	prolactin receptor binding(GO:0005148)
0.1	2.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	3.9	GO:0042605	peptide antigen binding(GO:0042605)
0.1	2.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.1	2.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	7.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.6	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	2.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.1	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.7	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.2	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.1	0.6	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.3	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	1.8	GO:0001848	complement binding(GO:0001848)
0.0	4.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0016595	glutamate binding(GO:0016595)
0.0	0.7	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.0	0.4	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.0	1.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.8	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.5	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.5	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	2.6	GO:0051087	chaperone binding(GO:0051087)
0.0	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.4	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.5	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	1.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0031432	titin binding(GO:0031432)
0.0	0.8	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.0	0.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	1.2	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	2.9	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.6	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.6	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	1.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	2.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	2.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.7	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.4	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.7	PID ATM PATHWAY	ATM pathway
0.0	1.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	1.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	4.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:1902769	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.7	3.3	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.6	3.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6	1.7	GO:0097052	tryptophan catabolic process to acetyl-CoA(GO:0019442) L-kynurenine metabolic process(GO:0097052)
0.5	1.5	GO:1903925	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.3	2.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.0	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.2	0.9	GO:0032690	negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2	3.1	GO:0051639	actin filament network formation(GO:0051639)
0.2	0.5	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
0.2	0.8	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	1.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1	0.4	GO:1904647	response to rotenone(GO:1904647)
0.1	0.6	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1	0.5	GO:0097068	response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1	2.3	GO:0005513	detection of calcium ion(GO:0005513)
0.1	2.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1	1.1	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	2.6	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	0.3	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1	0.5	GO:0006574	valine catabolic process(GO:0006574)
0.1	0.3	GO:0070512	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.1	0.3	GO:0019086	late viral transcription(GO:0019086)
0.1	1.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.2	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.1	0.3	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.1	0.7	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.1	4.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	7.5	GO:0030449	regulation of complement activation(GO:0030449)
0.1	1.0	GO:0015671	oxygen transport(GO:0015671)
0.1	0.7	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.8	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.1	0.5	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.3	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1	0.5	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.4	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.8	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.0	0.2	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0	0.2	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	1.0	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.5	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.2	GO:0014038	regulation of Schwann cell differentiation(GO:0014038)
0.0	0.1	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.0	0.4	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.8	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0	0.2	GO:1904798	positive regulation of core promoter binding(GO:1904798)
0.0	1.4	GO:0043029	T cell homeostasis(GO:0043029)
0.0	3.8	GO:0031295	T cell costimulation(GO:0031295)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	2.4	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.0	0.6	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.3	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	1.1	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.3	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.7	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	2.4	GO:0002819	regulation of adaptive immune response(GO:0002819)
0.0	2.3	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	1.5	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	1.3	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.5	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	6.3	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	2.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.1	1.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.1	1.7	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	2.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	1.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	3.6	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.9	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.6	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	1.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0005960	glycine cleavage complex(GO:0005960)
0.4	2.6	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.3	7.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	2.6	GO:0005577	fibrinogen complex(GO:0005577)
0.2	3.1	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.4	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	2.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.5	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.7	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.3	GO:0032279	asymmetric synapse(GO:0032279)
0.1	0.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.1	1.0	GO:0031209	SCAR complex(GO:0031209)
0.1	1.1	GO:0097342	ripoptosome(GO:0097342)
0.0	0.2	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.3	GO:0032437	cuticular plate(GO:0032437)
0.0	7.8	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.7	GO:0098576	lumenal side of membrane(GO:0098576)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.7	GO:0032040	small-subunit processome(GO:0032040)
0.0	3.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.3	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	0.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.7	GO:0016605	PML body(GO:0016605)
0.0	1.7	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.6	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)