ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
GFI1B Links Ensembl NCBI GeneCards UniProt	ENSG00000165702.8	GFI1B

Gene	Promoter	Pearson corr. coef.	P-value	Plot
GFI1B	hg19_v2_chr9_+_135854091_135854159	-0.73	1.3e-03	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr3_-_149688655	6.70	ENST00000461930.1 ENST00000423691.2 ENST00000490975.1 ENST00000461868.1 ENST00000452853.2	PFN2	profilin 2
chr9_-_14180778	6.12	ENST00000380924.1 ENST00000543693.1	NFIB	nuclear factor I/B
chr3_-_149688896	6.11	ENST00000239940.7	PFN2	profilin 2
chr10_+_124221036	5.29	ENST00000368984.3	HTRA1	HtrA serine peptidase 1
chr10_+_17272608	5.14	ENST00000421459.2	VIM	vimentin
chr6_+_12290586	5.12	ENST00000379375.5	EDN1	endothelin 1
chr14_-_53417732	4.85	ENST00000399304.3 ENST00000395631.2 ENST00000341590.3 ENST00000343279.4	FERMT2	fermitin family member 2
chr7_+_134576317	4.22	ENST00000424922.1 ENST00000495522.1	CALD1	caldesmon 1
chr1_-_68698222	3.96	ENST00000370976.3 ENST00000354777.2 ENST00000262348.4 ENST00000540432.1	WLS	wntless Wnt ligand secretion mediator
chr7_+_134576151	3.71	ENST00000393118.2	CALD1	caldesmon 1
chr7_+_79765071	3.69	ENST00000457358.2	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_+_116601265	3.47	ENST00000452085.3	DSE	dermatan sulfate epimerase
chr2_-_110371777	3.42	ENST00000397712.2	SEPT10	septin 10
chr6_+_21593972	3.41	ENST00000244745.1 ENST00000543472.1	SOX4	SRY (sex determining region Y)-box 4
chr2_-_110371720	3.35	ENST00000356688.4	SEPT10	septin 10
chr11_+_32112431	3.34	ENST00000054950.3	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr2_-_110371412	3.21	ENST00000415095.1 ENST00000334001.6 ENST00000437928.1 ENST00000493445.1 ENST00000397714.2 ENST00000461295.1	SEPT10	septin 10
chr1_-_94703118	3.20	ENST00000260526.6 ENST00000370217.3	ARHGAP29	Rho GTPase activating protein 29
chr2_-_190044480	3.12	ENST00000374866.3	COL5A2	collagen, type V, alpha 2
chr6_-_56707943	3.01	ENST00000370769.4 ENST00000421834.2 ENST00000312431.6 ENST00000361203.3 ENST00000523817.1	DST	dystonin
chr1_+_101702417	2.89	ENST00000305352.6	S1PR1	sphingosine-1-phosphate receptor 1
chr17_-_33759509	2.87	ENST00000304905.5	SLFN12	schlafen family member 12
chr14_-_93214988	2.82	ENST00000557434.1 ENST00000393218.2 ENST00000334869.4	LGMN	legumain
chr17_-_1395954	2.66	ENST00000359786.5	MYO1C	myosin IC
chr14_-_93214915	2.65	ENST00000553918.1 ENST00000555699.1 ENST00000553802.1 ENST00000554397.1 ENST00000554919.1 ENST00000554080.1 ENST00000553371.1	LGMN	legumain
chr21_+_35014783	2.59	ENST00000381291.4 ENST00000381285.4 ENST00000399367.3 ENST00000399352.1 ENST00000399355.2 ENST00000399349.1	ITSN1	intersectin 1 (SH3 domain protein)
chr8_-_49834299	2.56	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr16_+_69221028	2.50	ENST00000336278.4	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr5_+_15500280	2.50	ENST00000504595.1	FBXL7	F-box and leucine-rich repeat protein 7
chr7_+_134551583	2.43	ENST00000435928.1	CALD1	caldesmon 1
chr8_-_49833978	2.39	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr6_-_56708459	2.31	ENST00000370788.2	DST	dystonin
chr7_-_27196267	2.27	ENST00000242159.3	HOXA7	homeobox A7
chr18_-_5419797	2.24	ENST00000542146.1 ENST00000427684.2	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr2_-_208030647	2.24	ENST00000309446.6	KLF7	Kruppel-like factor 7 (ubiquitous)
chr3_+_50284321	2.22	ENST00000451956.1	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr8_-_6420777	2.18	ENST00000415216.1	ANGPT2	angiopoietin 2
chr8_-_6420930	2.15	ENST00000325203.5	ANGPT2	angiopoietin 2
chr2_-_110371664	2.13	ENST00000545389.1 ENST00000423520.1	SEPT10	septin 10
chr7_-_87856280	2.10	ENST00000490437.1 ENST00000431660.1	SRI	sorcin
chr4_-_156875003	2.10	ENST00000433477.3	CTSO	cathepsin O
chr12_+_48513570	2.09	ENST00000551804.1	PFKM	phosphofructokinase, muscle
chr14_-_23285069	2.09	ENST00000554758.1 ENST00000397528.4	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_23285011	2.09	ENST00000397532.3	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_237167718	2.06	ENST00000464121.2	MT1HL1	metallothionein 1H-like 1
chr1_-_23886285	2.03	ENST00000374561.5	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr15_+_32933866	2.01	ENST00000300175.4 ENST00000413748.2 ENST00000494364.1 ENST00000497208.1	SCG5	secretogranin V (7B2 protein)
chr5_-_125930929	2.00	ENST00000553117.1 ENST00000447989.2 ENST00000409134.3	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr17_-_46688334	1.98	ENST00000239165.7	HOXB7	homeobox B7
chr17_-_33864772	1.93	ENST00000361112.4	SLFN12L	schlafen family member 12-like
chr12_+_48513009	1.92	ENST00000359794.5 ENST00000551339.1 ENST00000395233.2 ENST00000548345.1	PFKM	phosphofructokinase, muscle
chr14_+_77228532	1.84	ENST00000167106.4 ENST00000554237.1	VASH1	vasohibin 1
chr16_+_50776021	1.83	ENST00000566679.2 ENST00000564634.1 ENST00000398568.2	CYLD	cylindromatosis (turban tumor syndrome)
chr4_-_186697044	1.81	ENST00000437304.2	SORBS2	sorbin and SH3 domain containing 2
chr1_-_68698197	1.76	ENST00000370973.2 ENST00000370971.1	WLS	wntless Wnt ligand secretion mediator
chr4_-_102268484	1.73	ENST00000394853.4	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_63661053	1.70	ENST00000279873.7	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr10_+_31610064	1.70	ENST00000446923.2 ENST00000559476.1	ZEB1	zinc finger E-box binding homeobox 1
chr1_+_39796810	1.69	ENST00000289893.4	MACF1	microtubule-actin crosslinking factor 1
chr2_-_86116093	1.66	ENST00000377332.3	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr7_-_108096765	1.62	ENST00000379024.4 ENST00000351718.4	NRCAM	neuronal cell adhesion molecule
chr7_-_115670804	1.55	ENST00000320239.7	TFEC	transcription factor EC
chr5_+_66254698	1.54	ENST00000405643.1 ENST00000407621.1 ENST00000432426.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr7_-_115670792	1.53	ENST00000265440.7 ENST00000393485.1	TFEC	transcription factor EC
chr20_-_4795747	1.49	ENST00000379376.2	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr1_+_162602244	1.43	ENST00000367922.3 ENST00000367921.3	DDR2	discoidin domain receptor tyrosine kinase 2
chr4_+_39184024	1.40	ENST00000399820.3 ENST00000509560.1 ENST00000512112.1 ENST00000288634.7 ENST00000506503.1	WDR19	WD repeat domain 19
chr19_-_44124019	1.39	ENST00000300811.3	ZNF428	zinc finger protein 428
chr5_+_109025067	1.36	ENST00000261483.4	MAN2A1	mannosidase, alpha, class 2A, member 1
chr17_-_19281203	1.34	ENST00000487415.2	B9D1	B9 protein domain 1
chr7_-_108096822	1.33	ENST00000379028.3 ENST00000413765.2 ENST00000379022.4	NRCAM	neuronal cell adhesion molecule
chr5_+_36608422	1.31	ENST00000381918.3	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_124155652	1.31	ENST00000426174.2 ENST00000303372.5	TCTN2	tectonic family member 2
chr15_+_71228826	1.31	ENST00000558456.1 ENST00000560158.2 ENST00000558808.1 ENST00000559806.1 ENST00000559069.1	LRRC49	leucine rich repeat containing 49
chr8_-_22926623	1.31	ENST00000276431.4	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b
chr17_+_19281034	1.30	ENST00000308406.5 ENST00000299612.7	MAPK7	mitogen-activated protein kinase 7
chr11_-_61659006	1.28	ENST00000278829.2	FADS3	fatty acid desaturase 3
chr1_+_164528866	1.27	ENST00000420696.2	PBX1	pre-B-cell leukemia homeobox 1
chrX_+_46696372	1.26	ENST00000218340.3	RP2	retinitis pigmentosa 2 (X-linked recessive)
chr8_-_6420565	1.25	ENST00000338312.6	ANGPT2	angiopoietin 2
chr16_+_50775971	1.23	ENST00000311559.9 ENST00000564326.1 ENST00000566206.1	CYLD	cylindromatosis (turban tumor syndrome)
chr6_+_153019069	1.20	ENST00000532295.1	MYCT1	myc target 1
chr6_+_30457244	1.19	ENST00000376630.4	HLA-E	major histocompatibility complex, class I, E
chr10_+_124134201	1.19	ENST00000368990.3 ENST00000368988.1 ENST00000368989.2 ENST00000463663.2	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_+_154125565	1.14	ENST00000338700.5	TRIM2	tripartite motif containing 2
chr7_-_86849025	1.14	ENST00000257637.3	TMEM243	transmembrane protein 243, mitochondrial
chr6_-_31648150	1.14	ENST00000375858.3 ENST00000383237.4	LY6G5C	lymphocyte antigen 6 complex, locus G5C
chr6_+_153019023	1.13	ENST00000367245.5 ENST00000529453.1	MYCT1	myc target 1
chr4_-_111558135	1.12	ENST00000394598.2 ENST00000394595.3	PITX2	paired-like homeodomain 2
chrX_+_49832231	1.11	ENST00000376108.3	CLCN5	chloride channel, voltage-sensitive 5
chr4_-_159080806	1.08	ENST00000590648.1	FAM198B	family with sequence similarity 198, member B
chr14_-_103523745	1.07	ENST00000361246.2	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr12_-_123752624	1.05	ENST00000542174.1 ENST00000535796.1	CDK2AP1	cyclin-dependent kinase 2 associated protein 1
chr2_-_158732340	1.05	ENST00000539637.1 ENST00000413751.1 ENST00000434821.1 ENST00000424669.1	ACVR1	activin A receptor, type I
chr3_-_119813264	1.04	ENST00000264235.8	GSK3B	glycogen synthase kinase 3 beta
chr15_-_34331243	1.03	ENST00000306730.3	AVEN	apoptosis, caspase activation inhibitor
chr2_-_136873735	1.03	ENST00000409817.1	CXCR4	chemokine (C-X-C motif) receptor 4
chr19_-_43708378	1.03	ENST00000599746.1	PSG4	pregnancy specific beta-1-glycoprotein 4
chr17_+_8213590	1.02	ENST00000361926.3	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr2_+_148602058	1.00	ENST00000241416.7 ENST00000535787.1 ENST00000404590.1	ACVR2A	activin A receptor, type IIA
chr4_+_26585538	0.98	ENST00000264866.4	TBC1D19	TBC1 domain family, member 19
chr10_+_71211212	0.98	ENST00000373290.2	TSPAN15	tetraspanin 15
chr16_-_18441131	0.97	ENST00000339303.5	NPIPA8	nuclear pore complex interacting protein family, member A8
chr7_+_39663061	0.97	ENST00000005257.2	RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr4_+_41362796	0.94	ENST00000508501.1 ENST00000512946.1 ENST00000313860.7 ENST00000512632.1 ENST00000512820.1	LIMCH1	LIM and calponin homology domains 1
chr3_-_165555200	0.92	ENST00000479451.1 ENST00000540653.1 ENST00000488954.1 ENST00000264381.3	BCHE	butyrylcholinesterase
chr3_-_158450475	0.92	ENST00000237696.5	RARRES1	retinoic acid receptor responder (tazarotene induced) 1
chr19_+_41770236	0.91	ENST00000392006.3	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr8_-_6420759	0.90	ENST00000523120.1	ANGPT2	angiopoietin 2
chr15_-_59041768	0.86	ENST00000402627.1 ENST00000396140.2 ENST00000559053.1 ENST00000561288.1	ADAM10	ADAM metallopeptidase domain 10
chr7_+_39663485	0.83	ENST00000436179.1	RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr2_-_130886795	0.83	ENST00000409914.2	POTEF	POTE ankyrin domain family, member F
chr11_+_5617952	0.82	ENST00000354852.5	TRIM6-TRIM34	TRIM6-TRIM34 readthrough
chr17_+_61699766	0.80	ENST00000579585.1 ENST00000584573.1 ENST00000361733.3 ENST00000361357.3	MAP3K3	mitogen-activated protein kinase kinase kinase 3
chr17_-_79481666	0.80	ENST00000575659.1	ACTG1	actin, gamma 1
chr22_-_37880543	0.78	ENST00000442496.1	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_+_93781728	0.77	ENST00000314622.4	NSUN3	NOP2/Sun domain family, member 3
chr2_+_234601512	0.77	ENST00000305139.6	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_-_115300579	0.76	ENST00000358528.4 ENST00000525132.1	CSDE1	cold shock domain containing E1, RNA-binding
chrX_+_7137475	0.76	ENST00000217961.4	STS	steroid sulfatase (microsomal), isozyme S
chr3_-_18466026	0.75	ENST00000417717.2	SATB1	SATB homeobox 1
chr6_+_71122974	0.74	ENST00000418814.2	FAM135A	family with sequence similarity 135, member A
chr1_+_220701740	0.73	ENST00000366917.4	MARK1	MAP/microtubule affinity-regulating kinase 1
chr6_-_7911042	0.73	ENST00000379757.4	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr18_+_11857439	0.72	ENST00000602628.1	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr16_+_50775948	0.71	ENST00000569681.1 ENST00000569418.1 ENST00000540145.1	CYLD	cylindromatosis (turban tumor syndrome)
chr11_-_26743546	0.71	ENST00000280467.6 ENST00000396005.3	SLC5A12	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr19_+_36236514	0.70	ENST00000222266.2	PSENEN	presenilin enhancer gamma secretase subunit
chr19_-_44123734	0.70	ENST00000598676.1	ZNF428	zinc finger protein 428
chr14_+_78870030	0.67	ENST00000553631.1 ENST00000554719.1	NRXN3	neurexin 3
chr2_+_201994208	0.67	ENST00000440180.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr14_+_58765103	0.66	ENST00000355431.3 ENST00000348476.3 ENST00000395168.3	ARID4A	AT rich interactive domain 4A (RBP1-like)
chr1_-_21377383	0.64	ENST00000374935.3	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr13_+_111806055	0.63	ENST00000218789.5	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr15_+_67458357	0.63	ENST00000537194.2	SMAD3	SMAD family member 3
chr19_-_58951496	0.60	ENST00000254166.3	ZNF132	zinc finger protein 132
chr2_+_201994042	0.60	ENST00000417748.1	CFLAR	CASP8 and FADD-like apoptosis regulator
chr19_+_41770269	0.59	ENST00000378215.4	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr9_+_35490101	0.59	ENST00000361226.3	RUSC2	RUN and SH3 domain containing 2
chr5_-_179334825	0.59	ENST00000355235.3 ENST00000356834.3	TBC1D9B	TBC1 domain family, member 9B (with GRAM domain)
chr17_+_61554413	0.58	ENST00000538928.1 ENST00000290866.4 ENST00000428043.1	ACE	angiotensin I converting enzyme
chr22_+_38864041	0.58	ENST00000216014.4 ENST00000409006.3	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr7_+_149535455	0.58	ENST00000223210.4 ENST00000460379.1	ZNF862	zinc finger protein 862
chr11_+_93861993	0.58	ENST00000227638.3 ENST00000436171.2	PANX1	pannexin 1
chr16_+_68279207	0.56	ENST00000413021.2 ENST00000565744.1 ENST00000219345.5	PLA2G15	phospholipase A2, group XV
chr5_-_137071756	0.56	ENST00000394937.3 ENST00000309755.4	KLHL3	kelch-like family member 3
chr5_-_137475071	0.56	ENST00000265191.2	NME5	NME/NM23 family member 5
chr3_-_158450231	0.56	ENST00000479756.1	RARRES1	retinoic acid receptor responder (tazarotene induced) 1
chr10_+_72575643	0.55	ENST00000373202.3	SGPL1	sphingosine-1-phosphate lyase 1
chr4_-_186696425	0.55	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr6_-_116601044	0.55	ENST00000368608.3	TSPYL1	TSPY-like 1
chr2_-_89160770	0.55	ENST00000390240.2	IGKJ3	immunoglobulin kappa joining 3
chr6_+_25963020	0.55	ENST00000357085.3	TRIM38	tripartite motif containing 38
chr1_-_115300592	0.53	ENST00000261443.5 ENST00000534699.1 ENST00000339438.6 ENST00000529046.1 ENST00000525970.1 ENST00000369530.1 ENST00000530886.1	CSDE1	cold shock domain containing E1, RNA-binding
chr9_-_95640218	0.52	ENST00000395506.3 ENST00000375495.3 ENST00000332591.6	ZNF484	zinc finger protein 484
chr16_-_18468926	0.51	ENST00000545114.1	RP11-1212A22.4	LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr6_+_90272027	0.50	ENST00000522441.1	ANKRD6	ankyrin repeat domain 6
chr2_-_9563469	0.49	ENST00000484735.1 ENST00000456913.2	ITGB1BP1	integrin beta 1 binding protein 1
chr1_-_230513367	0.49	ENST00000321327.2 ENST00000525115.1	PGBD5	piggyBac transposable element derived 5
chr1_-_21377447	0.48	ENST00000374937.3 ENST00000264211.8	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr19_+_36236491	0.48	ENST00000591949.1	PSENEN	presenilin enhancer gamma secretase subunit
chr18_-_48723690	0.48	ENST00000406189.3	MEX3C	mex-3 RNA binding family member C
chr11_+_74699703	0.48	ENST00000529024.1 ENST00000544263.1	NEU3	sialidase 3 (membrane sialidase)
chr21_+_47743995	0.47	ENST00000359568.5	PCNT	pericentrin
chr14_-_80677815	0.46	ENST00000557125.1 ENST00000555750.1	DIO2	deiodinase, iodothyronine, type II
chr2_-_45236540	0.44	ENST00000303077.6	SIX2	SIX homeobox 2
chr9_+_35538616	0.43	ENST00000455600.1	RUSC2	RUN and SH3 domain containing 2
chr14_-_80677970	0.42	ENST00000438257.4	DIO2	deiodinase, iodothyronine, type II
chr19_-_4831701	0.42	ENST00000248244.5	TICAM1	toll-like receptor adaptor molecule 1
chr3_+_173116225	0.42	ENST00000457714.1	NLGN1	neuroligin 1
chr2_+_242295658	0.40	ENST00000264042.3 ENST00000545004.1 ENST00000373287.4	FARP2	FERM, RhoGEF and pleckstrin domain protein 2
chr3_-_195619579	0.40	ENST00000428187.1	TNK2	tyrosine kinase, non-receptor, 2
chr2_-_9563319	0.39	ENST00000497105.1 ENST00000360635.3 ENST00000359712.3	ITGB1BP1	integrin beta 1 binding protein 1
chr10_-_49813090	0.39	ENST00000249601.4	ARHGAP22	Rho GTPase activating protein 22
chr19_+_3933085	0.38	ENST00000168977.2 ENST00000599576.1	NMRK2	nicotinamide riboside kinase 2
chr6_+_26440700	0.37	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3	butyrophilin, subfamily 3, member A3
chr19_-_4457776	0.37	ENST00000301281.6	UBXN6	UBX domain protein 6
chr3_-_15540055	0.36	ENST00000605797.1 ENST00000435459.2	COLQ	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr19_-_43269809	0.36	ENST00000406636.3 ENST00000404209.4 ENST00000306511.4	PSG8	pregnancy specific beta-1-glycoprotein 8
chr11_+_30253410	0.35	ENST00000533718.1	FSHB	follicle stimulating hormone, beta polypeptide
chr19_+_41770349	0.35	ENST00000602130.1	HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1
chr8_-_59412717	0.35	ENST00000301645.3	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr6_+_71123107	0.34	ENST00000370479.3 ENST00000505769.1 ENST00000515323.1 ENST00000515280.1 ENST00000507085.1 ENST00000457062.2 ENST00000361499.3	FAM135A	family with sequence similarity 135, member A
chr11_-_82746587	0.34	ENST00000528379.1 ENST00000534103.1	RAB30	RAB30, member RAS oncogene family
chr19_-_10687907	0.34	ENST00000589348.1	AP1M2	adaptor-related protein complex 1, mu 2 subunit
chr20_+_36974759	0.34	ENST00000217407.2	LBP	lipopolysaccharide binding protein
chr11_-_33774944	0.33	ENST00000532057.1 ENST00000531080.1	FBXO3	F-box protein 3
chr5_+_140529630	0.33	ENST00000543635.1	PCDHB6	protocadherin beta 6
chr6_-_131321863	0.32	ENST00000528282.1	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr20_-_57607347	0.32	ENST00000395663.1 ENST00000395659.1 ENST00000243997.3	ATP5E	ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chrX_+_84499081	0.32	ENST00000276123.3	ZNF711	zinc finger protein 711
chr5_+_14143728	0.31	ENST00000344204.4 ENST00000537187.1	TRIO	trio Rho guanine nucleotide exchange factor
chr17_-_79827808	0.30	ENST00000580685.1	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha
chr10_-_129924468	0.30	ENST00000368653.3	MKI67	marker of proliferation Ki-67
chr2_-_85788652	0.30	ENST00000430215.3	GGCX	gamma-glutamyl carboxylase
chr19_+_41103063	0.30	ENST00000308370.7	LTBP4	latent transforming growth factor beta binding protein 4
chr10_+_97471508	0.30	ENST00000453258.2	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr6_-_35765088	0.30	ENST00000259938.2	CLPS	colipase, pancreatic
chr15_-_42500351	0.29	ENST00000348544.4 ENST00000318006.5	VPS39	vacuolar protein sorting 39 homolog (S. cerevisiae)
chr4_+_56815102	0.28	ENST00000257287.4	CEP135	centrosomal protein 135kDa

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	5.7	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
1.8	5.5	GO:0006624	vacuolar protein processing(GO:0006624)
1.7	5.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.6	4.9	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.6	6.5	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
1.3	4.0	GO:0093001	glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.3	3.8	GO:1990108	protein linear deubiquitination(GO:1990108)
1.1	12.8	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
1.1	5.3	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
1.0	2.9	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.9	4.5	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.9	6.1	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8	3.1	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
0.7	4.4	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.6	1.8	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.6	5.3	GO:0008090	retrograde axonal transport(GO:0008090)
0.6	1.7	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.5	2.9	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.5	1.4	GO:0061055	myotome development(GO:0061055)
0.5	2.3	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.5	5.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.4	2.7	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	1.2	GO:0032679	antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.4	2.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.4	1.1	GO:0021763	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3	3.7	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.3	0.9	GO:0014016	neuroblast differentiation(GO:0014016)
0.3	2.1	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3	0.9	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3	2.0	GO:0042426	choline catabolic process(GO:0042426)
0.3	0.8	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.3	2.3	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.2	2.5	GO:0010265	SCF complex assembly(GO:0010265)
0.2	6.2	GO:0033622	integrin activation(GO:0033622)
0.2	1.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	1.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.2	1.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.2	1.7	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.2	1.3	GO:0006537	glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2	2.5	GO:0001973	adenosine receptor signaling pathway(GO:0001973)
0.2	1.4	GO:0006013	mannose metabolic process(GO:0006013)
0.2	1.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.2	0.7	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.2	1.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	1.8	GO:0051665	membrane raft localization(GO:0051665)
0.1	0.4	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	1.0	GO:0044800	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1	0.6	GO:1903597	negative regulation of gap junction assembly(GO:1903597)
0.1	0.6	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1	0.4	GO:0098923	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1	3.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	1.3	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.6	GO:1903243	negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1	0.3	GO:0046967	cytosol to ER transport(GO:0046967)
0.1	0.3	GO:0015920	leukocyte chemotaxis involved in inflammatory response(GO:0002232) lipopolysaccharide transport(GO:0015920)
0.1	1.4	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	1.2	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1	1.0	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.3	GO:0006788	heme oxidation(GO:0006788)
0.1	0.4	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1	0.6	GO:0070294	renal sodium ion absorption(GO:0070294)
0.1	0.9	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	0.5	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.7	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1	1.2	GO:0007220	Notch receptor processing(GO:0007220)
0.1	2.4	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1	0.3	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.8	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	0.6	GO:1904424	regulation of GTP binding(GO:1904424)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.2	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.1	0.4	GO:0045359	negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.8	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1	0.5	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1	1.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1	0.2	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.6	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0006524	alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.1	0.2	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	2.0	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:0032887	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0	2.0	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	1.7	GO:0016577	histone demethylation(GO:0016577)
0.0	0.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	1.1	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.4	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	2.0	GO:0048488	synaptic vesicle endocytosis(GO:0048488)
0.0	0.6	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.8	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.7	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.5	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.3	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.8	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.7	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	1.3	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.7	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.6	GO:0003351	epithelial cilium movement(GO:0003351)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0003220	left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) formation of anatomical boundary(GO:0048859) cell proliferation involved in heart valve development(GO:2000793)
0.0	0.2	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.0	1.1	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.4	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	1.6	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	2.7	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	0.3	GO:0044241	lipid digestion(GO:0044241)
0.0	1.4	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	1.4	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.3	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.2	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.9	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	1.0	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.3	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.4	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	1.1	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	6.9	GO:0006936	muscle contraction(GO:0006936)
0.0	1.8	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.3	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.3	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.4	6.6	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	12.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	1.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	6.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	6.1	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.2	4.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	10.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.0	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.1	4.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	1.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	4.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	2.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	4.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	2.6	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.4	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	0.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	0.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.7	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	3.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1	1.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	0.9	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	3.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.8	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	1.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	1.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	5.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	1.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	4.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.8	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	2.2	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	2.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	1.1	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.5	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
1.0	5.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.9	5.1	GO:1990254	keratin filament binding(GO:1990254)
0.7	4.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.4	5.7	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.4	4.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.4	3.8	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.4	3.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.3	8.9	GO:0005523	tropomyosin binding(GO:0005523)
0.3	2.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.3	1.4	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3	12.8	GO:0003785	actin monomer binding(GO:0003785)
0.2	2.9	GO:0046625	sphingosine-1-phosphate receptor activity(GO:0038036) sphingolipid binding(GO:0046625)
0.2	0.9	GO:0003990	acetylcholinesterase activity(GO:0003990)
0.2	2.9	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2	1.3	GO:0045569	TRAIL binding(GO:0045569)
0.2	0.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	0.6	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.2	1.3	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	2.7	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	1.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	2.9	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	4.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	0.8	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1	1.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	1.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	5.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	1.2	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.1	1.7	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.6	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	0.5	GO:0052795	exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.1	1.4	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	4.9	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	0.6	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241)
0.1	2.0	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.4	GO:0061769	ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1	1.0	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.1	0.3	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	2.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	2.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	6.5	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	2.0	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	4.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	10.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	0.6	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	1.7	GO:0070888	E-box binding(GO:0070888)
0.1	0.6	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.3	GO:0004707	MAP kinase activity(GO:0004707)
0.1	0.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1	0.2	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.1	0.5	GO:0008233	peptidase activity(GO:0008233)
0.1	0.2	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.1	1.7	GO:0032452	histone demethylase activity(GO:0032452)
0.1	1.1	GO:0000339	RNA cap binding(GO:0000339)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	4.9	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1	1.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.9	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	1.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.3	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.7	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.5	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	1.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.8	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	14.0	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	1.7	GO:0005504	fatty acid binding(GO:0005504)
0.0	2.5	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	1.9	GO:0019003	GDP binding(GO:0019003)
0.0	2.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	8.6	GO:0005525	GTP binding(GO:0005525)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0016831	carbon-carbon lyase activity(GO:0016830) carboxy-lyase activity(GO:0016831)
0.0	2.7	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.8	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	1.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.5	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.7	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.3	GO:0031673	H zone(GO:0031673)
1.0	3.1	GO:0005588	collagen type V trimer(GO:0005588)
0.8	4.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.8	5.5	GO:0036021	endolysosome lumen(GO:0036021)
0.7	3.0	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.7	10.4	GO:0030478	actin cap(GO:0030478)
0.7	2.7	GO:0045160	myosin I complex(GO:0045160)
0.5	6.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.3	1.4	GO:0005797	Golgi medial cisterna(GO:0005797)
0.3	1.3	GO:1990075	periciliary membrane compartment(GO:1990075)
0.3	2.1	GO:0044326	dendritic spine neck(GO:0044326)
0.3	1.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	1.4	GO:0030991	intraciliary transport particle A(GO:0030991)
0.2	5.7	GO:0032839	dendrite cytoplasm(GO:0032839)
0.2	1.7	GO:0005955	calcineurin complex(GO:0005955)
0.2	2.7	GO:0036038	MKS complex(GO:0036038)
0.2	1.8	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	2.9	GO:0043194	axon initial segment(GO:0043194)
0.1	2.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	4.9	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	12.8	GO:0043195	terminal bouton(GO:0043195)
0.1	1.3	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	6.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	1.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	1.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	3.8	GO:0097542	ciliary tip(GO:0097542)
0.1	1.0	GO:1990909	Wnt signalosome(GO:1990909)
0.1	0.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.6	GO:0000322	storage vacuole(GO:0000322)
0.1	0.6	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	2.5	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.1	0.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.8	GO:0097433	dense body(GO:0097433)
0.1	1.1	GO:0097342	ripoptosome(GO:0097342)
0.1	1.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0061673	cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.0	0.3	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	2.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0042825	TAP complex(GO:0042825)
0.0	4.8	GO:0005882	intermediate filament(GO:0005882)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
0.0	0.6	GO:0032059	bleb(GO:0032059)
0.0	0.4	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	5.1	GO:0030027	lamellipodium(GO:0030027)
0.0	0.2	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	1.8	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.5	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.8	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.6	GO:0036126	sperm flagellum(GO:0036126) sperm part(GO:0097223)
0.0	2.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
0.0	2.7	GO:0044798	nuclear transcription factor complex(GO:0044798)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	1.3	GO:0016605	PML body(GO:0016605)
0.0	0.9	GO:0042641	actomyosin(GO:0042641)
0.0	3.3	GO:0000790	nuclear chromatin(GO:0000790)
0.0	3.4	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	9.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.2	13.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	2.6	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	1.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.1	6.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	6.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	5.8	PID ENDOTHELIN PATHWAY	Endothelins
0.1	2.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.1	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.0	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	1.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	4.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	4.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	5.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	1.1	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	1.9	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	1.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	5.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.0	PID ALK1 PATHWAY	ALK1 signaling events
0.0	2.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	3.1	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	7.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.1	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes