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ENCODE cell lines, expression (Ernst 2011)

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Results for GLI3

Z-value: 1.28

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Transcription factors associated with GLI3

Gene Symbol Gene ID Gene Info
ENSG00000106571.8 GLI3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI3hg19_v2_chr7_-_42276612_422767820.411.2e-01Click!

Activity profile of GLI3 motif

Sorted Z-values of GLI3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_21529811 6.62 ENST00000588004.1
LAMA3
laminin, alpha 3
chr1_-_153538292 4.84 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr1_-_153538011 4.18 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr12_-_52887034 3.93 ENST00000330722.6
KRT6A
keratin 6A
chr20_+_62327996 3.86 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr17_-_39928106 3.74 ENST00000540235.1
JUP
junction plakoglobin
chr19_+_35606692 3.28 ENST00000406242.3
ENST00000454903.2
FXYD3
FXYD domain containing ion transport regulator 3
chr12_-_52845910 3.20 ENST00000252252.3
KRT6B
keratin 6B
chr1_+_183155373 3.19 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr12_-_52867569 3.14 ENST00000252250.6
KRT6C
keratin 6C
chr19_-_51456321 3.11 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr19_-_51456344 3.02 ENST00000336334.3
ENST00000593428.1
KLK5
kallikrein-related peptidase 5
chr6_+_125540951 2.88 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr17_+_15848231 2.67 ENST00000304222.2
ADORA2B
adenosine A2b receptor
chr4_-_90758227 2.33 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_+_31497271 2.05 ENST00000520407.1
NRG1
neuregulin 1
chr1_+_152956549 2.01 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr20_-_6104191 1.99 ENST00000217289.4
FERMT1
fermitin family member 1
chr19_-_51456198 1.93 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr16_+_68678739 1.81 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chrX_+_152086373 1.79 ENST00000318529.8
ZNF185
zinc finger protein 185 (LIM domain)
chr11_-_12030629 1.73 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr6_-_46703069 1.70 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr14_+_94577074 1.67 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr4_-_177713788 1.62 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr16_+_68679193 1.59 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr11_+_2415061 1.55 ENST00000481687.1
CD81
CD81 molecule
chr19_+_48281842 1.53 ENST00000509570.2
SEPW1
selenoprotein W, 1
chr17_+_73750699 1.52 ENST00000584939.1
ITGB4
integrin, beta 4
chr22_+_31489344 1.51 ENST00000404574.1
SMTN
smoothelin
chr8_-_42065187 1.50 ENST00000270189.6
ENST00000352041.3
ENST00000220809.4
PLAT
plasminogen activator, tissue
chr6_-_46703430 1.46 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_+_69931519 1.44 ENST00000316296.5
ENST00000530676.1
ANO1
anoctamin 1, calcium activated chloride channel
chr11_-_119991589 1.35 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr16_+_56598961 1.33 ENST00000219162.3
MT4
metallothionein 4
chr10_-_126847276 1.33 ENST00000531469.1
CTBP2
C-terminal binding protein 2
chr19_-_51522955 1.30 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr8_+_94929168 1.26 ENST00000518107.1
ENST00000396200.3
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_56119156 1.25 ENST00000421312.1
ENST00000416592.1
PSPH
phosphoserine phosphatase
chr20_+_55204351 1.23 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr12_+_6308881 1.23 ENST00000382518.1
ENST00000536586.1
CD9
CD9 molecule
chr2_+_192109911 1.21 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr19_-_12886327 1.21 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2
hook microtubule-tethering protein 2
chr8_+_94929077 1.21 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr22_+_31488433 1.20 ENST00000455608.1
SMTN
smoothelin
chr14_-_61748550 1.18 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr6_-_105627735 1.16 ENST00000254765.3
POPDC3
popeye domain containing 3
chr1_+_152881014 1.16 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr8_+_94929110 1.15 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr19_+_48281803 1.14 ENST00000601048.1
SEPW1
selenoprotein W, 1
chr1_+_44399466 1.14 ENST00000498139.2
ENST00000491846.1
ARTN
artemin
chr4_+_74735102 1.14 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr16_+_56691606 1.06 ENST00000334350.6
MT1F
metallothionein 1F
chr7_-_151511911 1.06 ENST00000392801.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_+_49713991 1.05 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr12_-_8814669 1.05 ENST00000535411.1
ENST00000540087.1
MFAP5
microfibrillar associated protein 5
chr19_+_48281946 1.04 ENST00000595615.1
SEPW1
selenoprotein W, 1
chr19_+_41281416 1.04 ENST00000597140.1
MIA
melanoma inhibitory activity
chr17_-_7307358 1.00 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr2_+_234637754 0.96 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr21_-_45079341 0.96 ENST00000443485.1
ENST00000291560.2
HSF2BP
heat shock transcription factor 2 binding protein
chr2_+_192110199 0.96 ENST00000304164.4
MYO1B
myosin IB
chr2_-_85636928 0.95 ENST00000449030.1
CAPG
capping protein (actin filament), gelsolin-like
chr19_+_48281928 0.94 ENST00000593892.1
SEPW1
selenoprotein W, 1
chr19_-_19051993 0.93 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr1_+_35220613 0.91 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr16_+_56691838 0.90 ENST00000394501.2
MT1F
metallothionein 1F
chr16_+_68771128 0.88 ENST00000261769.5
ENST00000422392.2
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr2_+_235860616 0.87 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr1_-_43833628 0.86 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr3_+_44626446 0.86 ENST00000441021.1
ENST00000322734.2
ZNF660
zinc finger protein 660
chr3_-_43663519 0.86 ENST00000427171.1
ENST00000292246.3
ANO10
anoctamin 10
chr19_+_41281060 0.86 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr16_+_57653854 0.85 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr12_-_54813229 0.82 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_41281282 0.81 ENST00000263369.3
MIA
melanoma inhibitory activity
chr2_-_24308051 0.80 ENST00000238721.4
ENST00000335934.4
TP53I3
tumor protein p53 inducible protein 3
chr16_+_57653989 0.80 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr8_-_145013711 0.80 ENST00000345136.3
PLEC
plectin
chr9_-_101017900 0.79 ENST00000375066.5
TBC1D2
TBC1 domain family, member 2
chr11_+_832944 0.78 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
CD151
CD151 molecule (Raph blood group)
chr9_-_101017862 0.78 ENST00000375064.1
ENST00000342112.5
TBC1D2
TBC1 domain family, member 2
chr3_-_43663389 0.77 ENST00000444344.1
ENST00000456438.1
ENST00000350459.4
ENST00000396091.3
ENST00000451430.2
ENST00000428472.1
ENST00000414522.2
ANO10
anoctamin 10
chr10_+_124134201 0.76 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_13910194 0.75 ENST00000376057.4
ENST00000510906.1
PDPN
podoplanin
chr18_+_3451646 0.74 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr8_-_145028013 0.74 ENST00000354958.2
PLEC
plectin
chr1_-_153433120 0.74 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr11_-_796197 0.74 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr7_-_41742697 0.74 ENST00000242208.4
INHBA
inhibin, beta A
chr1_+_233765353 0.73 ENST00000366620.1
KCNK1
potassium channel, subfamily K, member 1
chr7_-_24797546 0.73 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5
deafness, autosomal dominant 5
chr8_+_15397732 0.73 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
TUSC3
tumor suppressor candidate 3
chr9_+_132962843 0.71 ENST00000458469.1
NCS1
neuronal calcium sensor 1
chr7_-_56118981 0.70 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH
phosphoserine phosphatase
chr1_+_26869597 0.69 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr15_+_45422178 0.69 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr16_+_56691911 0.68 ENST00000568475.1
MT1F
metallothionein 1F
chr15_+_45422131 0.68 ENST00000321429.4
DUOX1
dual oxidase 1
chr16_-_84538218 0.67 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1
TBC/LysM-associated domain containing 1
chr11_-_61646054 0.67 ENST00000527379.1
FADS3
fatty acid desaturase 3
chr11_+_2407287 0.67 ENST00000381036.3
ENST00000492252.1
CD81
CD81 molecule
chr10_+_17270214 0.67 ENST00000544301.1
VIM
vimentin
chr16_-_68269971 0.66 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr12_-_120687948 0.65 ENST00000458477.2
PXN
paxillin
chr2_-_24307635 0.65 ENST00000313482.4
TP53I3
tumor protein p53 inducible protein 3
chr19_+_676385 0.65 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr11_+_832804 0.64 ENST00000397420.3
ENST00000525718.1
CD151
CD151 molecule (Raph blood group)
chr1_+_155293702 0.64 ENST00000368347.4
RUSC1
RUN and SH3 domain containing 1
chr1_+_26605618 0.63 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr16_+_27325202 0.62 ENST00000395762.2
ENST00000562142.1
ENST00000561742.1
ENST00000543915.2
ENST00000449195.1
ENST00000380922.3
ENST00000563002.1
IL4R
interleukin 4 receptor
chr16_+_4526341 0.62 ENST00000458134.3
ENST00000219700.6
ENST00000575120.1
ENST00000572812.1
ENST00000574466.1
ENST00000576827.1
ENST00000570445.1
HMOX2
heme oxygenase (decycling) 2
chr11_+_32851487 0.62 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr1_+_36621529 0.62 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr4_-_57524061 0.61 ENST00000508121.1
HOPX
HOP homeobox
chr2_-_85637459 0.61 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr11_-_535515 0.61 ENST00000311189.7
ENST00000451590.1
ENST00000417302.1
HRAS
Harvey rat sarcoma viral oncogene homolog
chr9_-_34637718 0.61 ENST00000378892.1
ENST00000277010.4
SIGMAR1
sigma non-opioid intracellular receptor 1
chr10_-_49701686 0.60 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr4_+_1283639 0.60 ENST00000303400.4
ENST00000505177.2
ENST00000503653.1
ENST00000264750.6
ENST00000502558.1
ENST00000452175.2
ENST00000514708.1
MAEA
macrophage erythroblast attacher
chrX_+_135229600 0.59 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr9_+_136223414 0.59 ENST00000371964.4
SURF2
surfeit 2
chr12_+_57984965 0.59 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr2_+_234545092 0.58 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr6_+_116601265 0.57 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr7_-_108096822 0.57 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr14_-_107211459 0.56 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr11_-_118550346 0.55 ENST00000530256.1
TREH
trehalase (brush-border membrane glycoprotein)
chr1_-_201368707 0.54 ENST00000391967.2
LAD1
ladinin 1
chr5_-_157002775 0.54 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr15_+_67430339 0.53 ENST00000439724.3
SMAD3
SMAD family member 3
chr12_-_57522813 0.53 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr9_-_27529726 0.53 ENST00000262244.5
MOB3B
MOB kinase activator 3B
chr19_-_45926739 0.53 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_-_134186144 0.53 ENST00000370775.2
FAM127B
family with sequence similarity 127, member B
chr1_+_167691185 0.52 ENST00000359523.2
MPZL1
myelin protein zero-like 1
chr5_-_79551838 0.52 ENST00000509193.1
ENST00000512972.2
SERINC5
serine incorporator 5
chr5_+_149340282 0.52 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr5_-_137878887 0.52 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr1_+_203595903 0.52 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr1_+_154947126 0.51 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr11_+_44117741 0.51 ENST00000395673.3
ENST00000343631.3
EXT2
exostosin glycosyltransferase 2
chr5_+_65892174 0.51 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr11_-_8986474 0.51 ENST00000525069.1
TMEM9B
TMEM9 domain family, member B
chr7_-_95064264 0.51 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
PON2
paraoxonase 2
chr11_+_844067 0.50 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr6_-_42016385 0.50 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr22_-_28197486 0.50 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr3_+_101568349 0.50 ENST00000326151.5
ENST00000326172.5
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr11_-_65667884 0.49 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr11_+_114168085 0.49 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase
chrX_+_135618258 0.49 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr3_+_187871060 0.49 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_47603109 0.49 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr1_-_146040968 0.49 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr4_-_102268484 0.48 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_+_154947148 0.47 ENST00000368436.1
ENST00000308987.5
CKS1B
CDC28 protein kinase regulatory subunit 1B
chrX_+_134166333 0.47 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chrX_+_151999511 0.47 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NSDHL
NAD(P) dependent steroid dehydrogenase-like
chr1_+_35544968 0.46 ENST00000359858.4
ENST00000373330.1
ZMYM1
zinc finger, MYM-type 1
chr3_-_127542051 0.46 ENST00000398104.1
MGLL
monoglyceride lipase
chr9_-_113800317 0.46 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr17_-_18161870 0.46 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII
flightless I homolog (Drosophila)
chrX_+_135229559 0.46 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr7_-_108096765 0.45 ENST00000379024.4
ENST00000351718.4
NRCAM
neuronal cell adhesion molecule
chr5_+_6633456 0.45 ENST00000274192.5
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr11_-_61658853 0.45 ENST00000525588.1
ENST00000540820.1
FADS3
fatty acid desaturase 3
chr7_-_24797032 0.45 ENST00000409970.1
ENST00000409775.3
DFNA5
deafness, autosomal dominant 5
chr11_+_124735282 0.45 ENST00000397801.1
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr9_-_139891165 0.45 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr14_-_74960030 0.44 ENST00000553490.1
ENST00000557510.1
NPC2
Niemann-Pick disease, type C2
chr19_+_18699535 0.44 ENST00000358607.6
C19orf60
chromosome 19 open reading frame 60
chr7_+_69064300 0.43 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr19_+_44084696 0.43 ENST00000562255.1
ENST00000569031.2
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr19_-_54693401 0.42 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr11_+_64949158 0.42 ENST00000527739.1
ENST00000526966.1
ENST00000533129.1
ENST00000524773.1
CAPN1
calpain 1, (mu/I) large subunit
chr1_-_160990886 0.42 ENST00000537746.1
F11R
F11 receptor
chr6_-_80657292 0.42 ENST00000369816.4
ELOVL4
ELOVL fatty acid elongase 4
chr11_+_64949343 0.42 ENST00000279247.6
ENST00000532285.1
ENST00000534373.1
CAPN1
calpain 1, (mu/I) large subunit
chr14_-_74959994 0.42 ENST00000238633.2
ENST00000434013.2
NPC2
Niemann-Pick disease, type C2
chrX_-_23761317 0.41 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
ACOT9
acyl-CoA thioesterase 9
chr21_-_33985127 0.40 ENST00000290155.3
C21orf59
chromosome 21 open reading frame 59
chr5_-_180237445 0.40 ENST00000393340.3
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_+_220701740 0.40 ENST00000366917.4
MARK1
MAP/microtubule affinity-regulating kinase 1
chr1_+_40505891 0.40 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr3_-_127542021 0.39 ENST00000434178.2
MGLL
monoglyceride lipase
chr11_+_64073699 0.39 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr7_+_44240520 0.39 ENST00000496112.1
ENST00000223369.2
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr19_-_51472031 0.39 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr2_+_17935119 0.39 ENST00000317402.7
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr7_+_116312411 0.38 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr9_-_113800341 0.38 ENST00000358883.4
LPAR1
lysophosphatidic acid receptor 1
chr18_+_11752040 0.38 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr14_+_29236269 0.38 ENST00000313071.4
FOXG1
forkhead box G1
chr9_-_130639997 0.38 ENST00000373176.1
AK1
adenylate kinase 1
chr1_+_155278539 0.38 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr6_+_31371337 0.37 ENST00000449934.2
ENST00000421350.1
MICA
MHC class I polypeptide-related sequence A
chr19_+_37464063 0.37 ENST00000586353.1
ENST00000433993.1
ENST00000592567.1
ZNF568
zinc finger protein 568
chr2_+_17935383 0.37 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr20_-_50808236 0.37 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 10.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 4.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
1.3 8.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
1.3 3.9 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.7 3.7 GO:0002159 desmosome assembly(GO:0002159)
0.7 2.7 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.6 2.2 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.5 3.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.5 14.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.5 2.3 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.4 1.7 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.4 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 1.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.4 GO:0042335 cuticle development(GO:0042335)
0.3 1.6 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.3 1.2 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.3 2.0 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 1.1 GO:1990736 positive regulation of cardiac conduction(GO:1903781) positive regulation of atrial cardiac muscle cell action potential(GO:1903949) positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.3 1.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 0.8 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.7 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 0.7 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0044209 AMP salvage(GO:0044209)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.8 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:0006788 heme oxidation(GO:0006788)
0.2 1.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 0.6 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 2.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 3.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 0.5 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 1.5 GO:0015705 iodide transport(GO:0015705)
0.2 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.8 GO:0051552 flavone metabolic process(GO:0051552)
0.2 0.5 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.7 GO:0045337 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 1.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.0 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.6 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.1 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 1.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.4 GO:2000395 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.4 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0035900 response to isolation stress(GO:0035900)
0.1 3.2 GO:0007398 ectoderm development(GO:0007398)
0.1 0.3 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 0.5 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.7 GO:0060992 response to fungicide(GO:0060992)
0.1 0.5 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.5 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.4 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 2.6 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.7 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1 0.3 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.3 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.9 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.1 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.1 3.1 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.3 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.8 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:0002933 lipid hydroxylation(GO:0002933) omega-hydroxylase P450 pathway(GO:0097267)
0.1 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.9 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 0.2 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.1 0.4 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.6 GO:0035721 intraciliary retrograde transport(GO:0035721) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.1 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 1.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 1.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 1.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619)
0.0 0.7 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.5 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 2.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0043090 amino acid import(GO:0043090)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.2 GO:1903960 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 1.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.5 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0002860 positive regulation of response to tumor cell(GO:0002836) positive regulation of immune response to tumor cell(GO:0002839) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.1 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 3.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.0 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 1.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 2.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.0 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:2000870 positive regulation of female gonad development(GO:2000196) regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:2000170 negative regulation of gap junction assembly(GO:1903597) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0015911 plasma membrane long-chain fatty acid transport(GO:0015911)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.9 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.3 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.1 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.7 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 2.7 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0035112 genitalia morphogenesis(GO:0035112)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.1 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.0 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532) positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
0.0 0.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.0 GO:1900166 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 2.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 3.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.4 3.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.4 1.9 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 1.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.7 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.5 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 1.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 1.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 2.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 2.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 0.5 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 1.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 2.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.7 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 2.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.7 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.1 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.7 GO:0005521 lamin binding(GO:0005521)
0.1 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 0.2 GO:0070404 NADH binding(GO:0070404)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 1.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 6.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 1.2 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.9 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 11.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 2.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.1 GO:0097209 epidermal lamellar body(GO:0097209)
1.1 3.2 GO:0005607 laminin-2 complex(GO:0005607)
0.8 6.6 GO:0005610 laminin-5 complex(GO:0005610)
0.5 3.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 1.2 GO:0070695 FHF complex(GO:0070695)
0.2 0.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 9.4 GO:0045095 keratin filament(GO:0045095)
0.2 0.6 GO:0005826 actomyosin contractile ring(GO:0005826) GID complex(GO:0034657)
0.2 3.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.6 GO:0097470 ribbon synapse(GO:0097470)
0.1 3.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0016342 catenin complex(GO:0016342)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.6 GO:0090543 Flemming body(GO:0090543)
0.1 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.5 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 1.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0043194 axon initial segment(GO:0043194)
0.1 3.2 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.1 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0070847 core mediator complex(GO:0070847)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 4.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 2.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 4.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.9 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 3.1 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 1.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 3.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 15.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 2.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.9 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs