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ENCODE cell lines, expression (Ernst 2011)

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Results for GUAAACA

Z-value: 0.61

Motif logo

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miRNA associated with seed GUAAACA

NamemiRBASE accession
hsa-miR-30a-5p
MIMAT0000087
hsa-miR-30b-5p
MIMAT0000420
hsa-miR-30c-5p
MIMAT0000244
hsa-miR-30d-5p
MIMAT0000245
hsa-miR-30e-5p
MIMAT0000692

Activity profile of GUAAACA motif

Sorted Z-values of GUAAACA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAAACA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_22688150 1.28 ENST00000454584.2
 GAS2
 growth arrest-specific 2
chr18_-_11148587 1.24 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
 PIEZO2
 piezo-type mechanosensitive ion channel component 2
chr10_-_52645416 1.18 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
 A1CF
 APOBEC1 complementation factor
chr14_+_101193164 1.13 ENST00000341267.4
 DLK1
 delta-like 1 homolog (Drosophila)
chr16_+_69599861 1.00 ENST00000354436.2
 NFAT5
 nuclear factor of activated T-cells 5, tonicity-responsive
chr17_+_53342311 0.99 ENST00000226067.5
 HLF
 hepatic leukemia factor
chr19_+_926000 0.98 ENST00000263620.3
 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
chr4_-_23891693 0.93 ENST00000264867.2
 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr9_-_6645628 0.92 ENST00000321612.6
 GLDC
 glycine dehydrogenase (decarboxylating)
chr15_-_61521495 0.92 ENST00000335670.6
 RORA
 RAR-related orphan receptor A
chr8_+_61591337 0.82 ENST00000423902.2
 CHD7
 chromodomain helicase DNA binding protein 7
chr2_+_42396472 0.82 ENST00000318522.5
ENST00000402711.2
 EML4
 echinoderm microtubule associated protein like 4
chr20_+_61448376 0.81 ENST00000343916.3
 COL9A3
 collagen, type IX, alpha 3
chr6_+_160390102 0.77 ENST00000356956.1
 IGF2R
 insulin-like growth factor 2 receptor
chr1_+_70876891 0.76 ENST00000411986.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chrX_-_39956656 0.74 ENST00000397354.3
ENST00000378444.4
 BCOR
 BCL6 corepressor
chr17_-_53499310 0.73 ENST00000262065.3
 MMD
 monocyte to macrophage differentiation-associated
chr14_-_38064198 0.72 ENST00000250448.2
 FOXA1
 forkhead box A1
chr22_+_21771656 0.70 ENST00000407464.2
 HIC2
 hypermethylated in cancer 2
chr1_+_213031570 0.69 ENST00000366971.4
 FLVCR1
 feline leukemia virus subgroup C cellular receptor 1
chr11_-_67888671 0.68 ENST00000265689.4
 CHKA
 choline kinase alpha
chr4_-_16077741 0.66 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
 PROM1
 prominin 1
chr19_+_18208603 0.66 ENST00000262811.6
 MAST3
 microtubule associated serine/threonine kinase 3
chr18_+_60190226 0.64 ENST00000269499.5
 ZCCHC2
 zinc finger, CCHC domain containing 2
chr17_-_42200996 0.63 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
 HDAC5
 histone deacetylase 5
chr12_-_31744031 0.57 ENST00000389082.5
 DENND5B
 DENN/MADD domain containing 5B
chr17_-_65241281 0.57 ENST00000358691.5
ENST00000580168.1
 HELZ
 helicase with zinc finger
chr2_-_24149977 0.56 ENST00000238789.5
 ATAD2B
 ATPase family, AAA domain containing 2B
chr16_+_2039946 0.55 ENST00000248121.2
ENST00000568896.1
 SYNGR3
 synaptogyrin 3
chr5_+_112312416 0.55 ENST00000389063.2
 DCP2
 decapping mRNA 2
chr18_+_55711575 0.55 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_-_236228403 0.54 ENST00000366595.3
 NID1
 nidogen 1
chr6_-_16761678 0.54 ENST00000244769.4
ENST00000436367.1
 ATXN1
 ataxin 1
chr18_+_55102917 0.54 ENST00000491143.2
 ONECUT2
 one cut homeobox 2
chr2_+_118846008 0.52 ENST00000245787.4
 INSIG2
 insulin induced gene 2
chr3_-_48700310 0.52 ENST00000164024.4
ENST00000544264.1
 CELSR3
 cadherin, EGF LAG seven-pass G-type receptor 3
chrX_+_23352133 0.52 ENST00000379361.4
 PTCHD1
 patched domain containing 1
chr20_-_30795511 0.52 ENST00000246229.4
 PLAGL2
 pleiomorphic adenoma gene-like 2
chr6_+_107811162 0.51 ENST00000317357.5
 SOBP
 sine oculis binding protein homolog (Drosophila)
chr2_-_166930131 0.50 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chr1_+_39456895 0.49 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
 AKIRIN1
 akirin 1
chr5_-_175964366 0.49 ENST00000274811.4
 RNF44
 ring finger protein 44
chr18_-_67624160 0.49 ENST00000581982.1
ENST00000280200.4
 CD226
 CD226 molecule
chr3_-_150481164 0.49 ENST00000312960.3
 SIAH2
 siah E3 ubiquitin protein ligase 2
chr17_-_74449252 0.48 ENST00000319380.7
 UBE2O
 ubiquitin-conjugating enzyme E2O
chr2_-_64371546 0.48 ENST00000358912.4
 PELI1
 pellino E3 ubiquitin protein ligase 1
chr16_+_22308717 0.48 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
 POLR3E
 polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr3_-_129407535 0.47 ENST00000432054.2
 TMCC1
 transmembrane and coiled-coil domain family 1
chr20_+_42295745 0.47 ENST00000396863.4
ENST00000217026.4
 MYBL2
 v-myb avian myeloblastosis viral oncogene homolog-like 2
chr2_-_239197201 0.46 ENST00000254658.3
 PER2
 period circadian clock 2
chrX_-_74376108 0.46 ENST00000339447.4
ENST00000373394.3
ENST00000529949.1
ENST00000534524.1
ENST00000253577.3
 ABCB7
 ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr6_+_15246501 0.46 ENST00000341776.2
 JARID2
 jumonji, AT rich interactive domain 2
chr10_+_73079000 0.46 ENST00000373189.5
 SLC29A3
 solute carrier family 29 (equilibrative nucleoside transporter), member 3
chr2_-_11484710 0.46 ENST00000315872.6
 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
chr10_-_23003460 0.46 ENST00000376573.4
 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr2_-_167232484 0.45 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
chr1_+_179923873 0.45 ENST00000367607.3
ENST00000491495.2
 CEP350
 centrosomal protein 350kDa
chr3_-_98312548 0.45 ENST00000264193.2
 CPOX
 coproporphyrinogen oxidase
chr12_-_12419703 0.44 ENST00000543091.1
ENST00000261349.4
 LRP6
 low density lipoprotein receptor-related protein 6
chr1_+_16174280 0.44 ENST00000375759.3
 SPEN
 spen family transcriptional repressor
chr1_-_154842741 0.43 ENST00000271915.4
 KCNN3
 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_-_82462425 0.43 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
 FAM46A
 family with sequence similarity 46, member A
chrX_-_33146477 0.43 ENST00000378677.2
 DMD
 dystrophin
chr1_+_15943995 0.42 ENST00000480945.1
 DDI2
 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr8_+_81397876 0.42 ENST00000430430.1
 ZBTB10
 zinc finger and BTB domain containing 10
chr13_+_113622810 0.42 ENST00000397030.1
 MCF2L
 MCF.2 cell line derived transforming sequence-like
chr15_-_34628951 0.42 ENST00000397707.2
ENST00000560611.1
 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
chr2_-_201828356 0.42 ENST00000234296.2
 ORC2
 origin recognition complex, subunit 2
chr5_-_98262240 0.41 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chr6_+_106546808 0.41 ENST00000369089.3
 PRDM1
 PR domain containing 1, with ZNF domain
chr18_-_12702769 0.41 ENST00000262127.2
 CEP76
 centrosomal protein 76kDa
chr2_+_234263120 0.41 ENST00000264057.2
ENST00000427930.1
 DGKD
 diacylglycerol kinase, delta 130kDa
chr10_-_88854518 0.40 ENST00000277865.4
 GLUD1
 glutamate dehydrogenase 1
chr1_-_115212696 0.40 ENST00000393276.3
ENST00000393277.1
 DENND2C
 DENN/MADD domain containing 2C
chr1_-_72748417 0.40 ENST00000357731.5
 NEGR1
 neuronal growth regulator 1
chr10_-_74856608 0.40 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
 P4HA1
 prolyl 4-hydroxylase, alpha polypeptide I
chr20_+_46130601 0.39 ENST00000341724.6
 NCOA3
 nuclear receptor coactivator 3
chr4_-_73434498 0.39 ENST00000286657.4
 ADAMTS3
 ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr11_-_115375107 0.39 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
 CADM1
 cell adhesion molecule 1
chr1_+_12123414 0.39 ENST00000263932.2
 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
chr22_+_21271714 0.38 ENST00000354336.3
 CRKL
 v-crk avian sarcoma virus CT10 oncogene homolog-like
chr15_-_65579177 0.38 ENST00000444347.2
ENST00000261888.6
 PARP16
 poly (ADP-ribose) polymerase family, member 16
chr1_+_155051305 0.38 ENST00000368408.3
 EFNA3
 ephrin-A3
chr14_+_55738021 0.37 ENST00000313833.4
 FBXO34
 F-box protein 34
chr17_+_70117153 0.37 ENST00000245479.2
 SOX9
 SRY (sex determining region Y)-box 9
chr21_-_16437255 0.37 ENST00000400199.1
ENST00000400202.1
 NRIP1
 nuclear receptor interacting protein 1
chr20_+_306221 0.37 ENST00000342665.2
 SOX12
 SRY (sex determining region Y)-box 12
chr17_-_79885576 0.37 ENST00000574686.1
ENST00000357736.4
 MAFG
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr20_-_45984401 0.36 ENST00000311275.7
 ZMYND8
 zinc finger, MYND-type containing 8
chr6_+_10556215 0.36 ENST00000316170.3
 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr1_+_11751748 0.36 ENST00000294485.5
 DRAXIN
 dorsal inhibitory axon guidance protein
chr17_-_74236382 0.36 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
 RNF157
 ring finger protein 157
chr2_-_68479614 0.36 ENST00000234310.3
 PPP3R1
 protein phosphatase 3, regulatory subunit B, alpha
chr4_-_39640700 0.35 ENST00000295958.5
 SMIM14
 small integral membrane protein 14
chr16_-_11350036 0.35 ENST00000332029.2
 SOCS1
 suppressor of cytokine signaling 1
chr8_-_82024290 0.35 ENST00000220597.4
 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
chr5_-_134369973 0.35 ENST00000265340.7
 PITX1
 paired-like homeodomain 1
chr2_-_200322723 0.35 ENST00000417098.1
 SATB2
 SATB homeobox 2
chr20_+_54933971 0.34 ENST00000371384.3
ENST00000437418.1
 FAM210B
 family with sequence similarity 210, member B
chr8_-_8751068 0.34 ENST00000276282.6
 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
chr7_+_26332645 0.34 ENST00000396376.1
 SNX10
 sorting nexin 10
chr4_-_74124502 0.34 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
 ANKRD17
 ankyrin repeat domain 17
chr1_-_108507631 0.34 ENST00000527011.1
ENST00000370056.4
 VAV3
 vav 3 guanine nucleotide exchange factor
chr14_+_105992906 0.34 ENST00000392519.2
 TMEM121
 transmembrane protein 121
chr3_+_142315225 0.34 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1
 plastin 1
chr1_+_114472222 0.34 ENST00000369558.1
ENST00000369561.4
 HIPK1
 homeodomain interacting protein kinase 1
chr17_+_1646130 0.34 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
 SERPINF2
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_-_115053781 0.33 ENST00000358465.2
ENST00000369543.2
 TRIM33
 tripartite motif containing 33
chr8_+_40010989 0.33 ENST00000315792.3
 C8orf4
 chromosome 8 open reading frame 4
chr20_-_52790512 0.33 ENST00000216862.3
 CYP24A1
 cytochrome P450, family 24, subfamily A, polypeptide 1
chr3_-_182698381 0.33 ENST00000292782.4
 DCUN1D1
 DCN1, defective in cullin neddylation 1, domain containing 1
chr1_+_174769006 0.32 ENST00000489615.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr8_+_107670064 0.32 ENST00000312046.6
 OXR1
 oxidation resistance 1
chr1_-_212004090 0.32 ENST00000366997.4
 LPGAT1
 lysophosphatidylglycerol acyltransferase 1
chr6_+_64281906 0.32 ENST00000370651.3
 PTP4A1
 protein tyrosine phosphatase type IVA, member 1
chr7_+_29874341 0.31 ENST00000409290.1
ENST00000242140.5
 WIPF3
 WAS/WASL interacting protein family, member 3
chr22_+_40573921 0.31 ENST00000454349.2
ENST00000335727.9
 TNRC6B
 trinucleotide repeat containing 6B
chrX_-_107975917 0.30 ENST00000563887.1
 RP6-24A23.6
 Uncharacterized protein
chr5_-_168006591 0.30 ENST00000239231.6
 PANK3
 pantothenate kinase 3
chr11_-_22647350 0.30 ENST00000327470.3
 FANCF
 Fanconi anemia, complementation group F
chr6_-_45345597 0.30 ENST00000371460.1
ENST00000371459.1
 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
chr11_-_119252359 0.30 ENST00000455332.2
 USP2
 ubiquitin specific peptidase 2
chr12_-_111021110 0.30 ENST00000354300.3
 PPTC7
 PTC7 protein phosphatase homolog (S. cerevisiae)
chr2_+_32288725 0.29 ENST00000315285.3
 SPAST
 spastin
chr2_+_95691417 0.29 ENST00000309988.4
 MAL
 mal, T-cell differentiation protein
chr2_-_39348137 0.29 ENST00000426016.1
 SOS1
 son of sevenless homolog 1 (Drosophila)
chr10_-_94003003 0.29 ENST00000412050.4
 CPEB3
 cytoplasmic polyadenylation element binding protein 3
chr10_+_76871454 0.29 ENST00000372687.4
 SAMD8
 sterile alpha motif domain containing 8
chr7_+_87505544 0.29 ENST00000265728.1
 DBF4
 DBF4 homolog (S. cerevisiae)
chr6_-_79787902 0.29 ENST00000275034.4
 PHIP
 pleckstrin homology domain interacting protein
chr3_+_9439400 0.29 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
 SETD5
 SET domain containing 5
chr6_+_391739 0.29 ENST00000380956.4
 IRF4
 interferon regulatory factor 4
chr9_-_112083229 0.29 ENST00000374566.3
ENST00000374557.4
 EPB41L4B
 erythrocyte membrane protein band 4.1 like 4B
chr1_+_93544791 0.28 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
 MTF2
 metal response element binding transcription factor 2
chr5_-_95297678 0.28 ENST00000237853.4
 ELL2
 elongation factor, RNA polymerase II, 2
chr2_+_120770645 0.28 ENST00000443902.2
 EPB41L5
 erythrocyte membrane protein band 4.1 like 5
chr13_-_39612176 0.28 ENST00000352251.3
ENST00000350125.3
 PROSER1
 proline and serine rich 1
chr22_+_50247449 0.28 ENST00000216268.5
 ZBED4
 zinc finger, BED-type containing 4
chr2_+_233562015 0.27 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
 GIGYF2
 GRB10 interacting GYF protein 2
chr12_+_94542459 0.27 ENST00000258526.4
 PLXNC1
 plexin C1
chr21_-_33104367 0.27 ENST00000286835.7
ENST00000399804.1
 SCAF4
 SR-related CTD-associated factor 4
chr17_-_61920280 0.27 ENST00000448276.2
ENST00000577990.1
 SMARCD2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr2_+_28615669 0.27 ENST00000379619.1
ENST00000264716.4
 FOSL2
 FOS-like antigen 2
chr11_+_117049445 0.27 ENST00000324225.4
ENST00000532960.1
 SIDT2
 SID1 transmembrane family, member 2
chrX_-_131352152 0.26 ENST00000342983.2
 RAP2C
 RAP2C, member of RAS oncogene family
chr6_+_108881012 0.26 ENST00000343882.6
 FOXO3
 forkhead box O3
chr2_+_169312350 0.26 ENST00000305747.6
 CERS6
 ceramide synthase 6
chr1_-_1709845 0.26 ENST00000341426.5
ENST00000344463.4
 NADK
 NAD kinase
chr15_-_37390482 0.26 ENST00000559085.1
ENST00000397624.3
 MEIS2
 Meis homeobox 2
chr10_-_46030841 0.25 ENST00000453424.2
 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr22_-_39239987 0.25 ENST00000333039.2
 NPTXR
 neuronal pentraxin receptor
chr7_+_66093851 0.25 ENST00000275532.3
 KCTD7
 potassium channel tetramerization domain containing 7
chr1_+_36348790 0.25 ENST00000373204.4
 AGO1
 argonaute RISC catalytic component 1
chr6_+_157802165 0.24 ENST00000414563.2
ENST00000359775.5
 ZDHHC14
 zinc finger, DHHC-type containing 14
chr3_-_53080047 0.24 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
 SFMBT1
 Scm-like with four mbt domains 1
chr9_-_100935043 0.24 ENST00000343933.5
 CORO2A
 coronin, actin binding protein, 2A
chr12_+_110906169 0.24 ENST00000377673.5
 FAM216A
 family with sequence similarity 216, member A
chr1_-_235491462 0.24 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
 ARID4B
 AT rich interactive domain 4B (RBP1-like)
chr21_+_30671189 0.24 ENST00000286800.3
 BACH1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_+_68119440 0.24 ENST00000346183.3
ENST00000329524.4
 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr5_-_147162078 0.23 ENST00000507386.1
 JAKMIP2
 janus kinase and microtubule interacting protein 2
chr5_+_179159813 0.23 ENST00000292599.3
 MAML1
 mastermind-like 1 (Drosophila)
chr4_+_160188889 0.23 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_103876965 0.23 ENST00000337198.5
 AZIN1
 antizyme inhibitor 1
chr16_-_87525651 0.23 ENST00000268616.4
 ZCCHC14
 zinc finger, CCHC domain containing 14
chr20_-_21494654 0.23 ENST00000377142.4
 NKX2-2
 NK2 homeobox 2
chr11_-_30038490 0.23 ENST00000328224.6
 KCNA4
 potassium voltage-gated channel, shaker-related subfamily, member 4
chr12_-_122751002 0.23 ENST00000267199.4
 VPS33A
 vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr3_+_180630090 0.23 ENST00000357559.4
ENST00000305586.7
 FXR1
 fragile X mental retardation, autosomal homolog 1
chr16_-_73082274 0.22 ENST00000268489.5
 ZFHX3
 zinc finger homeobox 3
chr5_+_75378997 0.22 ENST00000502798.2
 SV2C
 synaptic vesicle glycoprotein 2C
chr16_-_5083917 0.22 ENST00000312251.3
ENST00000381955.3
 NAGPA
 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_+_110559784 0.22 ENST00000282356.4
 CAMK4
 calcium/calmodulin-dependent protein kinase IV
chr8_+_38614807 0.22 ENST00000330691.6
ENST00000348567.4
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr6_-_13711773 0.22 ENST00000011619.3
 RANBP9
 RAN binding protein 9
chr16_+_68298405 0.22 ENST00000219343.6
ENST00000566834.1
ENST00000566454.1
 SLC7A6
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr8_+_87354945 0.22 ENST00000517970.1
 WWP1
 WW domain containing E3 ubiquitin protein ligase 1
chr4_-_89744457 0.21 ENST00000395002.2
 FAM13A
 family with sequence similarity 13, member A
chr12_+_2162447 0.21 ENST00000335762.5
ENST00000399655.1
 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
chr1_-_24194771 0.21 ENST00000374479.3
 FUCA1
 fucosidase, alpha-L- 1, tissue
chr13_+_97874574 0.21 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
 MBNL2
 muscleblind-like splicing regulator 2
chr5_+_133451254 0.21 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
chr18_+_52495426 0.20 ENST00000262094.5
 RAB27B
 RAB27B, member RAS oncogene family
chr9_-_115095883 0.20 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
 PTBP3
 polypyrimidine tract binding protein 3
chr20_+_60697480 0.20 ENST00000370915.1
ENST00000253001.4
ENST00000400318.2
ENST00000279068.6
ENST00000279069.7
 LSM14B
 LSM14B, SCD6 homolog B (S. cerevisiae)
chr15_-_45670924 0.20 ENST00000396659.3
 GATM
 glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_-_53409890 0.20 ENST00000229416.6
 GCLC
 glutamate-cysteine ligase, catalytic subunit
chr18_-_60987220 0.20 ENST00000398117.1
 BCL2
 B-cell CLL/lymphoma 2
chr6_+_47445467 0.20 ENST00000359314.5
 CD2AP
 CD2-associated protein
chr7_+_65338230 0.20 ENST00000360768.3
 VKORC1L1
 vitamin K epoxide reductase complex, subunit 1-like 1
chrX_+_120181457 0.20 ENST00000328078.1
 GLUD2
 glutamate dehydrogenase 2
chr2_-_70475730 0.20 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
 TIA1
 TIA1 cytotoxic granule-associated RNA binding protein
chr10_+_69644404 0.19 ENST00000212015.6
 SIRT1
 sirtuin 1
chr7_+_21467642 0.19 ENST00000222584.3
ENST00000432066.2
 SP4
 Sp4 transcription factor
chr20_-_524455 0.19 ENST00000349736.5
ENST00000217244.3
 CSNK2A1
 casein kinase 2, alpha 1 polypeptide
chr7_-_128695147 0.19 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
 TNPO3
 transportin 3
chr1_-_207224307 0.19 ENST00000315927.4
 YOD1
 YOD1 deubiquitinase
chr3_+_141205852 0.19 ENST00000286364.3
ENST00000452898.1
 RASA2
 RAS p21 protein activator 2
chr20_-_48330377 0.19 ENST00000371711.4
 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr10_-_15762124 0.19 ENST00000378076.3
 ITGA8
 integrin, alpha 8

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)
0.2 1.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 0.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 0.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.9 GO:0016594 glycine binding(GO:0016594)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.2 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 1.1 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.0 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.7 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) regulation of progesterone biosynthetic process(GO:2000182)
0.3 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.7 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2 1.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.8 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.9 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.7 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 0.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.2 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.3 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 0.4 GO:0060018 astrocyte fate commitment(GO:0060018) retinal rod cell differentiation(GO:0060221)
0.1 0.2 GO:0060926 cardiac pacemaker cell differentiation(GO:0060920) cardiac pacemaker cell development(GO:0060926)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 1.2 GO:0015886 heme transport(GO:0015886)
0.1 0.1 GO:0060374 mast cell differentiation(GO:0060374)
0.1 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0045082 interleukin-4 biosynthetic process(GO:0042097) positive regulation of interleukin-10 biosynthetic process(GO:0045082) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.2 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.3 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1 0.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 1.4 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.2 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.2 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.5 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 1.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0043317 regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.4 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.5 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.6 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 1.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.0 0.0 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.3 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.4 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.0 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.2 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0007270 neuron-neuron synaptic transmission(GO:0007270)
0.0 0.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.3 0.9 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 0.5 GO:0031523 Myb complex(GO:0031523)
0.1 0.4 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 1.2 GO:0097440 apical dendrite(GO:0097440)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.1 GO:0000502 proteasome complex(GO:0000502)
0.1 0.8 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0043596 replication fork(GO:0005657) nuclear replication fork(GO:0043596)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes