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ENCODE cell lines, expression (Ernst 2011)

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Results for GUAGUGU

Z-value: 1.33

Motif logo

logo of

miRNA associated with seed GUAGUGU

NamemiRBASE accession
hsa-miR-142-3p.1
MIMAT0000434

Activity profile of GUAGUGU motif

Sorted Z-values of GUAGUGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_38869410 5.61 ENST00000358869.2
 FAM114A1
 family with sequence similarity 114, member A1
chr3_-_123603137 4.34 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
 MYLK
 myosin light chain kinase
chr2_-_161350305 4.15 ENST00000348849.3
 RBMS1
 RNA binding motif, single stranded interacting protein 1
chr12_+_66217911 3.51 ENST00000403681.2
 HMGA2
 high mobility group AT-hook 2
chr22_-_36236265 3.18 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_187454749 3.01 ENST00000261023.3
ENST00000374907.3
 ITGAV
 integrin, alpha V
chr6_-_134639180 2.40 ENST00000367858.5
 SGK1
 serum/glucocorticoid regulated kinase 1
chr12_-_44200052 2.22 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
 TWF1
 twinfilin actin-binding protein 1
chr6_+_53659746 2.21 ENST00000370888.1
 LRRC1
 leucine rich repeat containing 1
chr16_-_4166186 2.06 ENST00000294016.3
 ADCY9
 adenylate cyclase 9
chr3_+_187930719 1.93 ENST00000312675.4
 LPP
 LIM domain containing preferred translocation partner in lipoma
chr1_+_7831323 1.88 ENST00000054666.6
 VAMP3
 vesicle-associated membrane protein 3
chr2_-_86790593 1.84 ENST00000263856.4
ENST00000409225.2
 CHMP3
 charged multivesicular body protein 3
chr2_+_9346892 1.83 ENST00000281419.3
ENST00000315273.4
 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr11_+_12695944 1.81 ENST00000361905.4
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chrX_+_134166333 1.79 ENST00000257013.7
 FAM127A
 family with sequence similarity 127, member A
chr9_-_80646374 1.50 ENST00000286548.4
 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
chr1_+_93913713 1.43 ENST00000604705.1
ENST00000370253.2
 FNBP1L
 formin binding protein 1-like
chr9_-_16870704 1.39 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
 BNC2
 basonuclin 2
chrX_+_37208521 1.38 ENST00000378628.4
 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
chr10_+_63661053 1.34 ENST00000279873.7
 ARID5B
 AT rich interactive domain 5B (MRF1-like)
chr2_+_5832799 1.34 ENST00000322002.3
 SOX11
 SRY (sex determining region Y)-box 11
chr6_-_33267101 1.33 ENST00000497454.1
 RGL2
 ral guanine nucleotide dissociation stimulator-like 2
chr17_-_8534067 1.31 ENST00000360416.3
ENST00000269243.4
 MYH10
 myosin, heavy chain 10, non-muscle
chr16_-_66785699 1.29 ENST00000258198.2
 DYNC1LI2
 dynein, cytoplasmic 1, light intermediate chain 2
chr10_-_81205373 1.23 ENST00000372336.3
 ZCCHC24
 zinc finger, CCHC domain containing 24
chr11_+_9406169 1.18 ENST00000379719.3
ENST00000527431.1
 IPO7
 importin 7
chr4_-_129208940 1.12 ENST00000296425.5
 PGRMC2
 progesterone receptor membrane component 2
chr2_+_198380289 1.12 ENST00000233892.4
ENST00000409916.1
 MOB4
 MOB family member 4, phocein
chr7_-_6523755 1.10 ENST00000436575.1
ENST00000258739.4
 DAGLB
KDELR2
 diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_34642656 1.03 ENST00000257831.3
ENST00000450654.2
 EHF
 ets homologous factor
chr3_-_114790179 1.02 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr4_-_102268628 1.01 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_-_14314066 1.00 ENST00000397575.3
 NFIB
 nuclear factor I/B
chr19_+_16187085 0.98 ENST00000300933.4
 TPM4
 tropomyosin 4
chr10_+_5726764 0.97 ENST00000328090.5
ENST00000496681.1
 FAM208B
 family with sequence similarity 208, member B
chr7_-_123389104 0.94 ENST00000223023.4
 WASL
 Wiskott-Aldrich syndrome-like
chr16_+_28875126 0.94 ENST00000359285.5
ENST00000538342.1
 SH2B1
 SH2B adaptor protein 1
chr16_-_87525651 0.91 ENST00000268616.4
 ZCCHC14
 zinc finger, CCHC domain containing 14
chr20_+_8112824 0.84 ENST00000378641.3
 PLCB1
 phospholipase C, beta 1 (phosphoinositide-specific)
chr2_-_39664405 0.83 ENST00000341681.5
ENST00000263881.3
 MAP4K3
 mitogen-activated protein kinase kinase kinase kinase 3
chr11_+_70244510 0.81 ENST00000346329.3
ENST00000301843.8
ENST00000376561.3
 CTTN
 cortactin
chr2_+_148602058 0.80 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
 ACVR2A
 activin A receptor, type IIA
chr11_+_57520715 0.80 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
 CTNND1
 catenin (cadherin-associated protein), delta 1
chr22_-_36784035 0.80 ENST00000216181.5
 MYH9
 myosin, heavy chain 9, non-muscle
chr11_-_76381781 0.79 ENST00000260061.5
ENST00000404995.1
 LRRC32
 leucine rich repeat containing 32
chr7_+_6414128 0.79 ENST00000348035.4
ENST00000356142.4
 RAC1
 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr19_-_15560730 0.78 ENST00000389282.4
ENST00000263381.7
 WIZ
 widely interspaced zinc finger motifs
chr10_+_134351319 0.75 ENST00000368594.3
ENST00000368593.3
 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
chr19_+_54694119 0.75 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
 TSEN34
 TSEN34 tRNA splicing endonuclease subunit
chr3_+_128968437 0.73 ENST00000314797.6
 COPG1
 coatomer protein complex, subunit gamma 1
chrX_-_134186144 0.71 ENST00000370775.2
 FAM127B
 family with sequence similarity 127, member B
chr7_-_151217001 0.69 ENST00000262187.5
 RHEB
 Ras homolog enriched in brain
chr14_-_81687197 0.68 ENST00000553612.1
 GTF2A1
 general transcription factor IIA, 1, 19/37kDa
chr21_-_44846999 0.65 ENST00000270162.6
 SIK1
 salt-inducible kinase 1
chr1_+_25071848 0.63 ENST00000374379.4
 CLIC4
 chloride intracellular channel 4
chr3_-_50396978 0.63 ENST00000266025.3
 TMEM115
 transmembrane protein 115
chr3_+_100428268 0.62 ENST00000240851.4
 TFG
 TRK-fused gene
chr2_-_11484710 0.61 ENST00000315872.6
 ROCK2
 Rho-associated, coiled-coil containing protein kinase 2
chr4_-_139163491 0.61 ENST00000280612.5
 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr6_-_30712313 0.59 ENST00000376377.2
ENST00000259874.5
 IER3
 immediate early response 3
chr6_+_34857019 0.58 ENST00000360359.3
ENST00000535627.1
 ANKS1A
 ankyrin repeat and sterile alpha motif domain containing 1A
chr10_-_32345305 0.57 ENST00000302418.4
 KIF5B
 kinesin family member 5B
chr7_-_41742697 0.56 ENST00000242208.4
 INHBA
 inhibin, beta A
chr21_-_39288743 0.55 ENST00000609713.1
 KCNJ6
 potassium inwardly-rectifying channel, subfamily J, member 6
chr11_-_85780086 0.54 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
 PICALM
 phosphatidylinositol binding clathrin assembly protein
chr12_+_122516626 0.50 ENST00000319080.7
 MLXIP
 MLX interacting protein
chr14_-_23504087 0.49 ENST00000493471.2
ENST00000460922.2
 PSMB5
 proteasome (prosome, macropain) subunit, beta type, 5
chr17_-_4167142 0.45 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
 ANKFY1
 ankyrin repeat and FYVE domain containing 1
chr21_-_39870339 0.44 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chrX_-_153285395 0.44 ENST00000369980.3
 IRAK1
 interleukin-1 receptor-associated kinase 1
chr20_-_61569227 0.42 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
 DIDO1
 death inducer-obliterator 1
chr5_+_35856951 0.42 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
 IL7R
 interleukin 7 receptor
chr10_+_17686124 0.41 ENST00000377524.3
 STAM
 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr11_+_120207787 0.40 ENST00000397843.2
ENST00000356641.3
 ARHGEF12
 Rho guanine nucleotide exchange factor (GEF) 12
chr9_+_36190853 0.40 ENST00000433436.2
ENST00000538225.1
ENST00000540080.1
 CLTA
 clathrin, light chain A
chr18_+_67956135 0.39 ENST00000397942.3
 SOCS6
 suppressor of cytokine signaling 6
chr13_+_49550015 0.39 ENST00000492622.2
 FNDC3A
 fibronectin type III domain containing 3A
chrX_-_102942961 0.39 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
 MORF4L2
 mortality factor 4 like 2
chr11_-_796197 0.38 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
 SLC25A22
 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chrX_-_41782249 0.37 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
 CASK
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_+_2699697 0.36 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
 RAP1GAP2
 RAP1 GTPase activating protein 2
chr17_-_27278304 0.36 ENST00000577226.1
 PHF12
 PHD finger protein 12
chr1_+_87170247 0.36 ENST00000370558.4
 SH3GLB1
 SH3-domain GRB2-like endophilin B1
chrX_+_49687216 0.36 ENST00000376088.3
 CLCN5
 chloride channel, voltage-sensitive 5
chr8_+_9413410 0.34 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr10_-_61666267 0.33 ENST00000263102.6
 CCDC6
 coiled-coil domain containing 6
chr15_-_78369994 0.32 ENST00000300584.3
ENST00000409931.3
 TBC1D2B
 TBC1 domain family, member 2B
chr12_-_117628333 0.31 ENST00000427718.2
 FBXO21
 F-box protein 21
chr6_+_114178512 0.29 ENST00000368635.4
 MARCKS
 myristoylated alanine-rich protein kinase C substrate
chr1_+_28099683 0.29 ENST00000373943.4
 STX12
 syntaxin 12
chr17_-_48474828 0.28 ENST00000576448.1
ENST00000225972.7
 LRRC59
 leucine rich repeat containing 59
chr1_+_218519577 0.28 ENST00000366930.4
ENST00000366929.4
 TGFB2
 transforming growth factor, beta 2
chr1_+_224544552 0.24 ENST00000465271.1
ENST00000366858.3
 CNIH4
 cornichon family AMPA receptor auxiliary protein 4
chr9_-_127703333 0.24 ENST00000373555.4
 GOLGA1
 golgin A1
chr10_+_31608054 0.23 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
 ZEB1
 zinc finger E-box binding homeobox 1
chr11_+_13299186 0.23 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
chr10_-_119806085 0.23 ENST00000355624.3
 RAB11FIP2
 RAB11 family interacting protein 2 (class I)
chr14_+_103851712 0.23 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
 MARK3
 MAP/microtubule affinity-regulating kinase 3
chr3_+_23986748 0.22 ENST00000312521.4
 NR1D2
 nuclear receptor subfamily 1, group D, member 2
chr16_+_10971037 0.22 ENST00000324288.8
ENST00000381835.5
 CIITA
 class II, major histocompatibility complex, transactivator
chr5_-_133512683 0.22 ENST00000353411.6
 SKP1
 S-phase kinase-associated protein 1
chr1_-_205719295 0.21 ENST00000367142.4
 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_-_74363803 0.20 ENST00000355773.5
 SLC17A5
 solute carrier family 17 (acidic sugar transporter), member 5
chr6_-_132834184 0.20 ENST00000367941.2
ENST00000367937.4
 STX7
 syntaxin 7
chr17_+_47865917 0.20 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
 KAT7
 K(lysine) acetyltransferase 7
chr11_+_111473108 0.18 ENST00000304987.3
 SIK2
 salt-inducible kinase 2
chr4_+_699537 0.17 ENST00000419774.1
ENST00000362003.5
ENST00000400151.2
ENST00000427463.1
ENST00000470161.2
 PCGF3
 polycomb group ring finger 3
chr5_+_140625147 0.17 ENST00000231173.3
 PCDHB15
 protocadherin beta 15
chr5_-_101632153 0.17 ENST00000310954.6
 SLCO4C1
 solute carrier organic anion transporter family, member 4C1
chr2_-_43453734 0.17 ENST00000282388.3
 ZFP36L2
 ZFP36 ring finger protein-like 2
chr5_+_95066823 0.16 ENST00000506817.1
ENST00000379982.3
 RHOBTB3
 Rho-related BTB domain containing 3
chr1_-_78148324 0.15 ENST00000370801.3
ENST00000433749.1
 ZZZ3
 zinc finger, ZZ-type containing 3
chr6_-_36953833 0.13 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
 MTCH1
 mitochondrial carrier 1
chr16_-_18937726 0.13 ENST00000389467.3
ENST00000446231.2
 SMG1
 SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_+_32645269 0.13 ENST00000373610.3
 TXLNA
 taxilin alpha
chr2_-_65357225 0.13 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
 RAB1A
 RAB1A, member RAS oncogene family
chr3_+_10857885 0.12 ENST00000254488.2
ENST00000454147.1
 SLC6A11
 solute carrier family 6 (neurotransmitter transporter), member 11
chr20_-_30310336 0.11 ENST00000434194.1
ENST00000376062.2
 BCL2L1
 BCL2-like 1
chr5_-_114961858 0.10 ENST00000282382.4
ENST00000456936.3
ENST00000408996.4
 TMED7-TICAM2
TMED7
TICAM2
 TMED7-TICAM2 readthrough
transmembrane emp24 protein transport domain containing 7
toll-like receptor adaptor molecule 2
chr8_+_61429416 0.10 ENST00000262646.7
ENST00000531289.1
 RAB2A
 RAB2A, member RAS oncogene family
chr19_+_45596218 0.09 ENST00000421905.1
ENST00000221462.4
 PPP1R37
 protein phosphatase 1, regulatory subunit 37
chr11_+_117014983 0.08 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
 PAFAH1B2
 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr17_+_44668035 0.08 ENST00000398238.4
ENST00000225282.8
 NSF
 N-ethylmaleimide-sensitive factor
chr17_-_62340581 0.08 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
 TEX2
 testis expressed 2
chr10_+_97803151 0.08 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
 CCNJ
 cyclin J
chr2_+_135676381 0.08 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
 CCNT2
 cyclin T2
chr2_+_198365122 0.07 ENST00000604458.1
 HSPE1-MOB4
 HSPE1-MOB4 readthrough
chr18_-_33647487 0.07 ENST00000590898.1
ENST00000357384.4
ENST00000319040.6
ENST00000588737.1
ENST00000399022.4
 RPRD1A
 regulation of nuclear pre-mRNA domain containing 1A
chr20_-_3996036 0.07 ENST00000336095.6
 RNF24
 ring finger protein 24
chr5_+_112043186 0.06 ENST00000509732.1
ENST00000457016.1
ENST00000507379.1
 APC
 adenomatous polyposis coli
chr4_-_16077741 0.06 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
 PROM1
 prominin 1
chr1_+_66797687 0.06 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
 PDE4B
 phosphodiesterase 4B, cAMP-specific
chr5_-_35230771 0.05 ENST00000342362.5
 PRLR
 prolactin receptor
chr12_-_54582655 0.03 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
 SMUG1
 single-strand-selective monofunctional uracil-DNA glycosylase 1
chr6_+_163835669 0.03 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
 QKI
 QKI, KH domain containing, RNA binding
chr2_+_210444142 0.02 ENST00000360351.4
ENST00000361559.4
 MAP2
 microtubule-associated protein 2
chr11_-_65381643 0.02 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
 MAP3K11
 mitogen-activated protein kinase kinase kinase 11
chr1_+_214161272 0.02 ENST00000498508.2
ENST00000366958.4
 PROX1
 prospero homeobox 1
chr3_+_93781728 0.01 ENST00000314622.4
 NSUN3
 NOP2/Sun domain family, member 3
chr1_+_94883931 0.01 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
 ABCD3
 ATP-binding cassette, sub-family D (ALD), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0031049 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.8 3.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.5 4.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 3.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 1.3 GO:0061386 closure of optic fissure(GO:0061386)
0.4 2.2 GO:0030047 actin modification(GO:0030047)
0.4 1.3 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.3 2.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 1.0 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.3 0.9 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.3 0.8 GO:0090427 activation of meiosis(GO:0090427)
0.3 1.9 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.3 0.8 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.3 0.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 0.7 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.6 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 0.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 2.1 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) positive regulation of catagen(GO:0051795)
0.1 0.8 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.6 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.9 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 1.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.8 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.4 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 2.1 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.7 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 1.4 GO:0043586 tongue development(GO:0043586)
0.0 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 1.8 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.7 GO:0051683 establishment of Golgi localization(GO:0051683)
0.0 1.3 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 1.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.8 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0045348 positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:2000698 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781) beta-catenin destruction complex assembly(GO:1904885)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0035501 MH1 domain binding(GO:0035501)
0.9 4.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 3.0 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 1.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.3 0.8 GO:0070984 SET domain binding(GO:0070984)
0.3 1.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.8 GO:0098821 inhibin binding(GO:0034711) BMP receptor activity(GO:0098821)
0.1 0.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 2.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.8 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 2.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.7 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) PH domain binding(GO:0042731)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 3.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 3.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 2.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 3.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 5.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 2.1 GO:0097513 myosin II filament(GO:0097513)
0.4 1.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 3.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 0.6 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 4.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0012505 endomembrane system(GO:0012505)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0043073 germ cell nucleus(GO:0043073)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.8 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 5.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 3.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.4 PID INSULIN PATHWAY Insulin Pathway
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway