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ENCODE cell lines, expression (Ernst 2011)

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Results for GZF1

Z-value: 0.79

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.11 GZF1

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_52535712 3.12 ENST00000216286.5
ENST00000541773.1
 NID2
 nidogen 2 (osteonidogen)
chr3_-_87040233 2.12 ENST00000398399.2
 VGLL3
 vestigial like 3 (Drosophila)
chr3_-_114035026 1.78 ENST00000570269.1
 RP11-553L6.5
 RP11-553L6.5
chr18_-_53303123 1.68 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
 TCF4
 transcription factor 4
chr1_+_26606608 1.19 ENST00000319041.6
 SH3BGRL3
 SH3 domain binding glutamic acid-rich protein like 3
chr1_-_144995002 1.08 ENST00000369356.4
 PDE4DIP
 phosphodiesterase 4D interacting protein
chrX_+_54835493 1.02 ENST00000396224.1
 MAGED2
 melanoma antigen family D, 2
chr1_-_144994909 0.84 ENST00000369347.4
ENST00000369354.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr1_-_144995074 0.83 ENST00000534536.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr14_-_92413353 0.78 ENST00000556154.1
 FBLN5
 fibulin 5
chr10_-_126849588 0.76 ENST00000411419.2
 CTBP2
 C-terminal binding protein 2
chr10_-_126849068 0.75 ENST00000494626.2
ENST00000337195.5
 CTBP2
 C-terminal binding protein 2
chr14_-_92413727 0.70 ENST00000267620.10
 FBLN5
 fibulin 5
chr3_+_30647994 0.69 ENST00000295754.5
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr5_+_92919043 0.58 ENST00000327111.3
 NR2F1
 nuclear receptor subfamily 2, group F, member 1
chr3_+_30648066 0.57 ENST00000359013.4
 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
chr14_+_101292445 0.53 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
 MEG3
 maternally expressed 3 (non-protein coding)
chr20_+_42086525 0.44 ENST00000244020.3
 SRSF6
 serine/arginine-rich splicing factor 6
chr9_+_96338647 0.41 ENST00000359246.4
 PHF2
 PHD finger protein 2
chr1_-_144994840 0.41 ENST00000369351.3
ENST00000369349.3
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr1_-_226374373 0.39 ENST00000366812.5
 ACBD3
 acyl-CoA binding domain containing 3
chr7_-_27183263 0.33 ENST00000222726.3
 HOXA5
 homeobox A5
chrX_+_102883620 0.32 ENST00000372626.3
 TCEAL1
 transcription elongation factor A (SII)-like 1
chr12_+_107168418 0.30 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr1_-_32801825 0.28 ENST00000329421.7
 MARCKSL1
 MARCKS-like 1
chr9_+_96338860 0.23 ENST00000375376.4
 PHF2
 PHD finger protein 2
chr12_+_104458235 0.23 ENST00000229330.4
 HCFC2
 host cell factor C2
chr9_-_14308004 0.21 ENST00000493697.1
 NFIB
 nuclear factor I/B
chr9_+_131133598 0.16 ENST00000372853.4
ENST00000452446.1
ENST00000372850.1
ENST00000372847.1
 URM1
 ubiquitin related modifier 1
chr12_-_76478417 0.13 ENST00000552342.1
 NAP1L1
 nucleosome assembly protein 1-like 1
chr12_-_76478386 0.13 ENST00000535020.2
 NAP1L1
 nucleosome assembly protein 1-like 1
chr14_-_21979428 0.11 ENST00000538267.1
ENST00000298717.4
 METTL3
 methyltransferase like 3
chr10_+_89264625 0.10 ENST00000371996.4
ENST00000371994.4
 MINPP1
 multiple inositol-polyphosphate phosphatase 1
chr2_-_150444300 0.09 ENST00000303319.5
 MMADHC
 methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr12_-_76478446 0.08 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
 NAP1L1
 nucleosome assembly protein 1-like 1
chr14_+_22293618 0.07 ENST00000390432.2
 TRAV10
 T cell receptor alpha variable 10
chr2_-_150444116 0.07 ENST00000428879.1
ENST00000422782.2
 MMADHC
 methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr7_+_102004322 0.06 ENST00000496391.1
 PRKRIP1
 PRKR interacting protein 1 (IL11 inducible)
chr7_-_105029812 0.04 ENST00000482897.1
 SRPK2
 SRSF protein kinase 2
chr6_+_30524663 0.02 ENST00000376560.3
 PRR3
 proline rich 3
chr6_+_30525051 0.01 ENST00000376557.3
 PRR3
 proline rich 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.6 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.1 3.1 GO:0071711 basement membrane organization(GO:0071711)
0.1 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 1.2 GO:0030834 regulation of actin filament depolymerization(GO:0030834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 1.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0052827 inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0071953 elastic fiber(GO:0071953)
0.1 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 3.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction