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ENCODE cell lines, expression (Ernst 2011)

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Results for HES7_HES5

Z-value: 1.05

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Transcription factors associated with HES7_HES5

Gene Symbol Gene ID Gene Info
HES7
ENSG00000179111.4 HES7
HES5
ENSG00000197921.5 HES5

Activity profile of HES7_HES5 motif

Sorted Z-values of HES7_HES5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HES7_HES5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_62084241 2.88 ENST00000449662.2
 ICAM2
 intercellular adhesion molecule 2
chr22_+_44464923 2.26 ENST00000404989.1
 PARVB
 parvin, beta
chr7_-_27205136 2.01 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr19_+_35168633 1.82 ENST00000505365.2
 ZNF302
 zinc finger protein 302
chr5_+_95066823 1.70 ENST00000506817.1
ENST00000379982.3
 RHOBTB3
 Rho-related BTB domain containing 3
chr13_+_43597269 1.44 ENST00000379221.2
 DNAJC15
 DnaJ (Hsp40) homolog, subfamily C, member 15
chr13_+_35516390 1.33 ENST00000540320.1
ENST00000400445.3
ENST00000310336.4
 NBEA
 neurobeachin
chr3_+_39851094 1.31 ENST00000302541.6
 MYRIP
 myosin VIIA and Rab interacting protein
chr2_+_201981119 1.31 ENST00000395148.2
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr14_+_65879437 1.24 ENST00000394585.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr12_-_49318715 1.20 ENST00000444214.2
 FKBP11
 FK506 binding protein 11, 19 kDa
chr5_-_150537279 1.08 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
 ANXA6
 annexin A6
chr19_+_4304632 1.03 ENST00000597590.1
 FSD1
 fibronectin type III and SPRY domain containing 1
chr6_+_13182751 1.00 ENST00000415087.1
 PHACTR1
 phosphatase and actin regulator 1
chr14_+_65879668 0.99 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr2_-_175870085 0.98 ENST00000409156.3
 CHN1
 chimerin 1
chr3_-_69062764 0.92 ENST00000295571.5
 EOGT
 EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_-_26232522 0.89 ENST00000399728.1
 STMN1
 stathmin 1
chr19_+_4304585 0.85 ENST00000221856.6
 FSD1
 fibronectin type III and SPRY domain containing 1
chr3_+_49027308 0.84 ENST00000383729.4
ENST00000343546.4
 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr1_-_26232951 0.84 ENST00000426559.2
ENST00000455785.2
 STMN1
 stathmin 1
chr11_-_63376013 0.83 ENST00000540943.1
 PLA2G16
 phospholipase A2, group XVI
chr10_+_180405 0.83 ENST00000439456.1
ENST00000397962.3
ENST00000309776.4
ENST00000381602.4
 ZMYND11
 zinc finger, MYND-type containing 11
chr6_-_112194484 0.75 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
 FYN
 FYN oncogene related to SRC, FGR, YES
chr9_+_92219919 0.72 ENST00000252506.6
ENST00000375769.1
 GADD45G
 growth arrest and DNA-damage-inducible, gamma
chr2_+_201981527 0.68 ENST00000441224.1
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr20_-_36793663 0.65 ENST00000536701.1
ENST00000536724.1
 TGM2
 transglutaminase 2
chr20_-_36793774 0.65 ENST00000361475.2
 TGM2
 transglutaminase 2
chr5_-_143550241 0.63 ENST00000522203.1
 YIPF5
 Yip1 domain family, member 5
chr5_-_143550159 0.63 ENST00000448443.2
ENST00000513112.1
ENST00000519064.1
ENST00000274496.5
 YIPF5
 Yip1 domain family, member 5
chr3_-_125820348 0.62 ENST00000509064.1
ENST00000508835.1
 SLC41A3
 solute carrier family 41, member 3
chr1_-_201476274 0.56 ENST00000340006.2
 CSRP1
 cysteine and glycine-rich protein 1
chr19_-_3700388 0.55 ENST00000589578.1
ENST00000537021.1
ENST00000539785.1
ENST00000335312.3
 PIP5K1C
 phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
chr12_+_112204691 0.54 ENST00000416293.3
ENST00000261733.2
 ALDH2
 aldehyde dehydrogenase 2 family (mitochondrial)
chr21_-_46330545 0.53 ENST00000320216.6
ENST00000397852.1
 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_201170703 0.51 ENST00000358677.5
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr2_+_201980827 0.50 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr17_+_30813576 0.47 ENST00000313401.3
 CDK5R1
 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_+_152870106 0.47 ENST00000285900.5
 GRIA1
 glutamate receptor, ionotropic, AMPA 1
chr9_+_103204553 0.41 ENST00000502978.1
ENST00000334943.6
 MSANTD3-TMEFF1
TMEFF1
 MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_52904425 0.41 ENST00000535450.1
 SGCB
 sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr1_-_26233423 0.40 ENST00000357865.2
 STMN1
 stathmin 1
chr17_-_35969409 0.39 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
 SYNRG
 synergin, gamma
chr14_+_24641062 0.38 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
 REC8
 REC8 meiotic recombination protein
chr4_-_76439483 0.38 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
 RCHY1
 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr15_-_57025759 0.37 ENST00000267807.7
 ZNF280D
 zinc finger protein 280D
chr1_-_231114542 0.36 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
 TTC13
 tetratricopeptide repeat domain 13
chr22_-_31741757 0.32 ENST00000215919.3
 PATZ1
 POZ (BTB) and AT hook containing zinc finger 1
chr3_+_38537763 0.32 ENST00000287675.5
ENST00000358249.2
ENST00000422077.2
 EXOG
 endo/exonuclease (5'-3'), endonuclease G-like
chr14_+_65878565 0.31 ENST00000556518.1
ENST00000557164.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr12_+_103351444 0.30 ENST00000266744.3
 ASCL1
 achaete-scute family bHLH transcription factor 1
chr19_-_19049791 0.29 ENST00000594439.1
ENST00000221222.11
 HOMER3
 homer homolog 3 (Drosophila)
chr5_+_148521046 0.29 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
 ABLIM3
 actin binding LIM protein family, member 3
chr2_-_86564776 0.28 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
 REEP1
 receptor accessory protein 1
chr5_+_148521136 0.28 ENST00000506113.1
 ABLIM3
 actin binding LIM protein family, member 3
chr5_+_148521381 0.28 ENST00000504238.1
 ABLIM3
 actin binding LIM protein family, member 3
chr1_-_1293904 0.28 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
 MXRA8
 matrix-remodelling associated 8
chr7_+_44788430 0.27 ENST00000457123.1
ENST00000309315.4
 ZMIZ2
 zinc finger, MIZ-type containing 2
chr16_-_67969888 0.25 ENST00000574576.2
 PSMB10
 proteasome (prosome, macropain) subunit, beta type, 10
chr10_+_131265443 0.24 ENST00000306010.7
 MGMT
 O-6-methylguanine-DNA methyltransferase
chr4_-_76439596 0.23 ENST00000451788.1
ENST00000512706.1
 RCHY1
 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr7_+_101460882 0.22 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
 CUX1
 cut-like homeobox 1
chr17_+_5185552 0.21 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
 RABEP1
 rabaptin, RAB GTPase binding effector protein 1
chr11_-_14380664 0.21 ENST00000545643.1
ENST00000256196.4
 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
chr13_+_115047097 0.21 ENST00000351487.5
 UPF3A
 UPF3 regulator of nonsense transcripts homolog A (yeast)
chr11_-_6440624 0.20 ENST00000311051.3
 APBB1
 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr12_+_6644443 0.20 ENST00000396858.1
 GAPDH
 glyceraldehyde-3-phosphate dehydrogenase
chr4_+_94750014 0.19 ENST00000306011.3
 ATOH1
 atonal homolog 1 (Drosophila)
chr20_-_44539538 0.18 ENST00000372420.1
 PLTP
 phospholipid transfer protein
chr22_+_24891210 0.18 ENST00000382760.2
 UPB1
 ureidopropionase, beta
chr4_+_2819883 0.18 ENST00000511747.1
ENST00000503393.2
 SH3BP2
 SH3-domain binding protein 2
chr14_+_90422239 0.17 ENST00000393452.3
ENST00000554180.1
ENST00000393454.2
ENST00000553617.1
ENST00000335725.4
ENST00000357382.3
ENST00000556867.1
ENST00000553527.1
 TDP1
 tyrosyl-DNA phosphodiesterase 1
chr11_+_9595180 0.17 ENST00000450114.2
 WEE1
 WEE1 G2 checkpoint kinase
chr17_+_46048376 0.15 ENST00000338399.4
 CDK5RAP3
 CDK5 regulatory subunit associated protein 3
chr5_-_114598548 0.15 ENST00000379615.3
ENST00000419445.1
 PGGT1B
 protein geranylgeranyltransferase type I, beta subunit
chr22_+_22681656 0.15 ENST00000390291.2
 IGLV1-50
 immunoglobulin lambda variable 1-50 (non-functional)
chr9_-_23821842 0.15 ENST00000544538.1
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr13_+_27998681 0.15 ENST00000381140.4
 GTF3A
 general transcription factor IIIA
chr11_+_35684288 0.14 ENST00000299413.5
 TRIM44
 tripartite motif containing 44
chr15_+_81489213 0.14 ENST00000559383.1
ENST00000394660.2
 IL16
 interleukin 16
chr14_-_67826486 0.14 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
 ATP6V1D
 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr16_-_5115913 0.13 ENST00000474471.3
 C16orf89
 chromosome 16 open reading frame 89
chr2_-_219925189 0.12 ENST00000295731.6
 IHH
 indian hedgehog
chr20_+_35201993 0.12 ENST00000373872.4
 TGIF2
 TGFB-induced factor homeobox 2
chr20_+_35201857 0.11 ENST00000373874.2
 TGIF2
 TGFB-induced factor homeobox 2
chr11_+_67776012 0.11 ENST00000539229.1
 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
chr17_+_48172639 0.11 ENST00000503176.1
ENST00000503614.1
 PDK2
 pyruvate dehydrogenase kinase, isozyme 2
chrX_-_149106653 0.11 ENST00000462691.1
ENST00000370404.1
ENST00000483447.1
ENST00000370409.3
 CXorf40B
 chromosome X open reading frame 40B
chr9_+_100174344 0.11 ENST00000422139.2
 TDRD7
 tudor domain containing 7
chrX_-_153523462 0.11 ENST00000361930.3
ENST00000369926.1
 TEX28
 testis expressed 28
chr9_-_100395756 0.11 ENST00000341170.4
ENST00000354801.2
 TSTD2
 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr7_+_148959262 0.10 ENST00000434415.1
 ZNF783
 zinc finger family member 783
chr11_+_70049269 0.10 ENST00000301838.4
 FADD
 Fas (TNFRSF6)-associated via death domain
chr9_+_131549483 0.10 ENST00000372648.5
ENST00000539497.1
 TBC1D13
 TBC1 domain family, member 13
chr22_+_41777927 0.09 ENST00000266304.4
 TEF
 thyrotrophic embryonic factor
chr2_+_201980961 0.09 ENST00000342795.5
 CFLAR
 CASP8 and FADD-like apoptosis regulator
chr5_+_179125907 0.09 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
 CANX
 calnexin
chr10_+_72194585 0.09 ENST00000420338.2
 AC022532.1
 Uncharacterized protein
chr8_+_38089198 0.09 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
 DDHD2
 DDHD domain containing 2
chr17_-_42907564 0.09 ENST00000592524.1
 GJC1
 gap junction protein, gamma 1, 45kDa
chr10_+_22605304 0.09 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
 COMMD3-BMI1
COMMD3
 COMMD3-BMI1 readthrough
COMM domain containing 3
chr8_-_65711310 0.08 ENST00000310193.3
 CYP7B1
 cytochrome P450, family 7, subfamily B, polypeptide 1
chr19_-_36054555 0.08 ENST00000262623.3
 ATP4A
 ATPase, H+/K+ exchanging, alpha polypeptide
chr2_-_198299726 0.08 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
 SF3B1
 splicing factor 3b, subunit 1, 155kDa
chr19_-_52511334 0.08 ENST00000602063.1
ENST00000597747.1
ENST00000594083.1
ENST00000593650.1
ENST00000599631.1
ENST00000598071.1
ENST00000601178.1
ENST00000376716.5
ENST00000391795.3
 ZNF615
 zinc finger protein 615
chr17_-_18950950 0.08 ENST00000284154.5
 GRAP
 GRB2-related adaptor protein
chr2_-_86116093 0.08 ENST00000377332.3
 ST3GAL5
 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_65216462 0.08 ENST00000234256.3
 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_-_73184588 0.07 ENST00000395145.2
 CLDN3
 claudin 3
chr10_+_22605374 0.07 ENST00000448361.1
 COMMD3
 COMM domain containing 3
chr7_+_99933730 0.07 ENST00000610247.1
 PILRB
 paired immunoglobin-like type 2 receptor beta
chr16_+_3550924 0.07 ENST00000576634.1
ENST00000574369.1
ENST00000341633.5
ENST00000417763.2
ENST00000571025.1
 CLUAP1
 clusterin associated protein 1
chr15_+_68871569 0.07 ENST00000566799.1
 CORO2B
 coronin, actin binding protein, 2B
chr19_+_6135646 0.07 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
 ACSBG2
 acyl-CoA synthetase bubblegum family member 2
chr9_+_100395891 0.06 ENST00000375147.3
 NCBP1
 nuclear cap binding protein subunit 1, 80kDa
chr4_+_6202448 0.06 ENST00000508601.1
 RP11-586D19.1
 RP11-586D19.1
chr1_+_152658599 0.05 ENST00000368780.3
 LCE2B
 late cornified envelope 2B
chr7_+_4815238 0.05 ENST00000348624.4
ENST00000401897.1
 AP5Z1
 adaptor-related protein complex 5, zeta 1 subunit
chr5_+_152870287 0.05 ENST00000340592.5
 GRIA1
 glutamate receptor, ionotropic, AMPA 1
chr16_-_48419361 0.05 ENST00000394725.2
 SIAH1
 siah E3 ubiquitin protein ligase 1
chr21_+_45432174 0.05 ENST00000380221.3
ENST00000291574.4
 TRAPPC10
 trafficking protein particle complex 10
chr2_-_220108309 0.05 ENST00000409640.1
 GLB1L
 galactosidase, beta 1-like
chr19_+_50691437 0.04 ENST00000598205.1
 MYH14
 myosin, heavy chain 14, non-muscle
chr14_-_77737543 0.04 ENST00000298352.4
 NGB
 neuroglobin
chr14_+_67826709 0.04 ENST00000256383.4
 EIF2S1
 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_-_169769787 0.04 ENST00000451987.1
 SPC25
 SPC25, NDC80 kinetochore complex component
chr1_+_160765919 0.03 ENST00000341032.4
ENST00000368041.2
ENST00000368040.1
 LY9
 lymphocyte antigen 9
chr22_+_18560675 0.03 ENST00000329627.7
 PEX26
 peroxisomal biogenesis factor 26
chr1_+_160765884 0.03 ENST00000392203.4
 LY9
 lymphocyte antigen 9
chr1_+_160765860 0.02 ENST00000368037.5
 LY9
 lymphocyte antigen 9
chrX_+_153524024 0.02 ENST00000369915.3
ENST00000217905.7
 TKTL1
 transketolase-like 1
chr2_+_25264933 0.02 ENST00000401432.3
ENST00000403714.3
 EFR3B
 EFR3 homolog B (S. cerevisiae)
chr4_+_184580420 0.02 ENST00000334690.6
ENST00000357207.4
 TRAPPC11
 trafficking protein particle complex 11
chr14_-_106967788 0.01 ENST00000390622.2
 IGHV1-46
 immunoglobulin heavy variable 1-46
chrY_-_26194116 0.01 ENST00000306882.4
ENST00000382407.1
 CDY1B
 chromodomain protein, Y-linked, 1B
chr4_+_128886532 0.01 ENST00000444616.1
ENST00000388795.5
 C4orf29
 chromosome 4 open reading frame 29
chr1_-_45140074 0.01 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
 TMEM53
 transmembrane protein 53
chr8_+_17780483 0.01 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
 PCM1
 pericentriolar material 1
chr2_+_201171372 0.01 ENST00000409140.3
 SPATS2L
 spermatogenesis associated, serine-rich 2-like
chr11_+_65154070 0.00 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
 FRMD8
 FERM domain containing 8

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 3.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.8 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.5 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 2.7 GO:0005123 death receptor binding(GO:0005123)
0.1 0.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.2 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172) DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0036071 N-glycan fucosylation(GO:0036071)
0.4 2.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4 1.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 2.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.3 2.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.4 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 2.0 GO:0042118 endothelial cell activation(GO:0042118)
0.2 0.5 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0021529 noradrenergic neuron development(GO:0003358) neuroblast differentiation(GO:0014016) spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) stem cell fate determination(GO:0048867) regulation of timing of neuron differentiation(GO:0060164) olfactory pit development(GO:0060166)
0.1 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 1.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0072683 T cell extravasation(GO:0072683)
0.0 0.7 GO:1900745 activation of MAPKKK activity(GO:0000185) positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 3.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.8 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.7 GO:0097342 ripoptosome(GO:0097342)
0.1 0.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.5 GO:0044308 axonal spine(GO:0044308)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 3.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)