Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for HESX1

Z-value: 0.70

Motif logo

logo of

Transcription factors associated with HESX1

Gene Symbol Gene ID Gene Info
HESX1
ENSG00000163666.4 HESX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HESX1hg19_v2_chr3_-_57233966_57234014-0.126.7e-01Click!

Activity profile of HESX1 motif

Sorted Z-values of HESX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_15168624 1.80 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
 PMP22
 peripheral myelin protein 22
chr2_-_1748214 1.34 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
 PXDN
 peroxidasin homolog (Drosophila)
chr7_+_130126165 1.20 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
 MEST
 mesoderm specific transcript
chr6_-_167275991 1.15 ENST00000510118.1
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_-_98290087 1.02 ENST00000322128.3
 TSPYL5
 TSPY-like 5
chr1_+_165600083 0.96 ENST00000367889.3
 MGST3
 microsomal glutathione S-transferase 3
chr15_+_80733570 0.86 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
 ARNT2
 aryl-hydrocarbon receptor nuclear translocator 2
chr17_-_57184260 0.81 ENST00000376149.3
ENST00000393066.3
 TRIM37
 tripartite motif containing 37
chr6_+_52285131 0.80 ENST00000433625.2
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr8_+_79428539 0.78 ENST00000352966.5
 PKIA
 protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr5_-_179780312 0.73 ENST00000253778.8
 GFPT2
 glutamine-fructose-6-phosphate transaminase 2
chr6_+_52285046 0.73 ENST00000371068.5
 EFHC1
 EF-hand domain (C-terminal) containing 1
chr17_-_57184064 0.69 ENST00000262294.7
 TRIM37
 tripartite motif containing 37
chr17_+_45286706 0.67 ENST00000393450.1
ENST00000572303.1
 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
chr15_-_89089860 0.61 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
 DET1
 de-etiolated homolog 1 (Arabidopsis)
chr17_+_45286387 0.59 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
chr12_+_53491220 0.58 ENST00000548547.1
ENST00000301464.3
 IGFBP6
 insulin-like growth factor binding protein 6
chr5_+_149340282 0.56 ENST00000286298.4
 SLC26A2
 solute carrier family 26 (anion exchanger), member 2
chr5_+_40679584 0.56 ENST00000302472.3
 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
chr8_-_101963482 0.56 ENST00000419477.2
 YWHAZ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_-_128399706 0.55 ENST00000426981.1
 LIMS2
 LIM and senescent cell antigen-like domains 2
chr14_+_61654271 0.53 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr4_+_83956237 0.49 ENST00000264389.2
 COPS4
 COP9 signalosome subunit 4
chr12_-_49582593 0.48 ENST00000295766.5
 TUBA1A
 tubulin, alpha 1a
chr3_+_158519654 0.46 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr16_+_57279248 0.45 ENST00000562023.1
ENST00000563234.1
 ARL2BP
 ADP-ribosylation factor-like 2 binding protein
chr4_+_83956312 0.44 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
 COPS4
 COP9 signalosome subunit 4
chr8_-_93029865 0.44 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_+_54318616 0.41 ENST00000254442.3
 WDR7
 WD repeat domain 7
chr17_+_47572647 0.40 ENST00000172229.3
 NGFR
 nerve growth factor receptor
chr15_-_83316711 0.40 ENST00000568128.1
 CPEB1
 cytoplasmic polyadenylation element binding protein 1
chr2_-_197036289 0.39 ENST00000263955.4
 STK17B
 serine/threonine kinase 17b
chr1_-_169337176 0.36 ENST00000472647.1
ENST00000367811.3
 NME7
 NME/NM23 family member 7
chr18_+_54318566 0.34 ENST00000589935.1
ENST00000357574.3
 WDR7
 WD repeat domain 7
chr21_-_34852304 0.33 ENST00000542230.2
 TMEM50B
 transmembrane protein 50B
chr4_-_2264015 0.28 ENST00000337190.2
 MXD4
 MAX dimerization protein 4
chr7_+_12727250 0.28 ENST00000404894.1
 ARL4A
 ADP-ribosylation factor-like 4A
chr1_-_17216143 0.26 ENST00000457075.1
 RP11-108M9.4
 RP11-108M9.4
chr11_-_5276008 0.24 ENST00000336906.4
 HBG2
 hemoglobin, gamma G
chr14_-_70883708 0.22 ENST00000256366.4
 SYNJ2BP
 synaptojanin 2 binding protein
chr2_-_160654745 0.22 ENST00000259053.4
ENST00000429078.2
 CD302
 CD302 molecule
chr12_-_123717643 0.22 ENST00000541437.1
ENST00000606320.1
 MPHOSPH9
 M-phase phosphoprotein 9
chr17_+_73089382 0.22 ENST00000538213.2
ENST00000584118.1
 SLC16A5
 solute carrier family 16 (monocarboxylate transporter), member 5
chr15_+_22892663 0.21 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
 CYFIP1
 cytoplasmic FMR1 interacting protein 1
chr6_+_31939608 0.21 ENST00000375331.2
ENST00000375333.2
 STK19
 serine/threonine kinase 19
chr4_+_156588350 0.20 ENST00000296518.7
 GUCY1A3
 guanylate cyclase 1, soluble, alpha 3
chr19_+_2249308 0.20 ENST00000592877.1
ENST00000221496.4
 AMH
 anti-Mullerian hormone
chr11_+_73019282 0.18 ENST00000263674.3
 ARHGEF17
 Rho guanine nucleotide exchange factor (GEF) 17
chr16_-_57219966 0.17 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
 FAM192A
 family with sequence similarity 192, member A
chr11_+_64323098 0.17 ENST00000301891.4
 SLC22A11
 solute carrier family 22 (organic anion/urate transporter), member 11
chr4_+_6784401 0.17 ENST00000425103.1
ENST00000307659.5
 KIAA0232
 KIAA0232
chr2_-_89310012 0.17 ENST00000493819.1
 IGKV1-9
 immunoglobulin kappa variable 1-9
chr15_+_80351910 0.17 ENST00000261749.6
ENST00000561060.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr21_-_38445443 0.16 ENST00000360525.4
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_165738085 0.16 ENST00000464650.1
ENST00000392129.6
 TMCO1
 transmembrane and coiled-coil domains 1
chr19_-_50370509 0.16 ENST00000596014.1
 PNKP
 polynucleotide kinase 3'-phosphatase
chr14_-_24664540 0.16 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
 TM9SF1
 transmembrane 9 superfamily member 1
chr11_-_126138808 0.16 ENST00000332118.6
ENST00000532259.1
 SRPR
 signal recognition particle receptor (docking protein)
chr1_-_165738072 0.16 ENST00000481278.1
 TMCO1
 transmembrane and coiled-coil domains 1
chr7_-_74267836 0.16 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
 GTF2IRD2
 GTF2I repeat domain containing 2
chr19_+_47634039 0.16 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
 SAE1
 SUMO1 activating enzyme subunit 1
chr7_+_127228399 0.16 ENST00000000233.5
ENST00000415666.1
 ARF5
 ADP-ribosylation factor 5
chr19_-_50370799 0.15 ENST00000600910.1
ENST00000322344.3
ENST00000600573.1
 PNKP
 polynucleotide kinase 3'-phosphatase
chr22_+_20105259 0.15 ENST00000416427.1
ENST00000421656.1
ENST00000423859.1
ENST00000418705.2
 RANBP1
 RAN binding protein 1
chr16_+_56659687 0.15 ENST00000568293.1
ENST00000330439.6
 MT1E
 metallothionein 1E
chr8_+_120885949 0.15 ENST00000523492.1
ENST00000286234.5
 DEPTOR
 DEP domain containing MTOR-interacting protein
chr10_-_75634326 0.14 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
 CAMK2G
 calcium/calmodulin-dependent protein kinase II gamma
chr7_+_74508372 0.14 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
 GTF2IRD2B
 GTF2I repeat domain containing 2B
chr6_-_41888814 0.14 ENST00000409060.1
ENST00000265350.4
 MED20
 mediator complex subunit 20
chr1_+_151372010 0.14 ENST00000290541.6
 PSMB4
 proteasome (prosome, macropain) subunit, beta type, 4
chr3_+_46921732 0.14 ENST00000418619.1
 PTH1R
 parathyroid hormone 1 receptor
chr1_-_54637997 0.13 ENST00000536061.1
 AL357673.1
 CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr1_-_203320617 0.13 ENST00000354955.4
 FMOD
 fibromodulin
chr8_+_97274119 0.13 ENST00000455950.2
 PTDSS1
 phosphatidylserine synthase 1
chr12_+_13197218 0.13 ENST00000197268.8
 KIAA1467
 KIAA1467
chr14_-_106068065 0.12 ENST00000390541.2
 IGHE
 immunoglobulin heavy constant epsilon
chr1_-_43638168 0.12 ENST00000431635.2
 EBNA1BP2
 EBNA1 binding protein 2
chr2_-_96931679 0.12 ENST00000258439.3
ENST00000432959.1
 TMEM127
 transmembrane protein 127
chr1_-_109968973 0.12 ENST00000271308.4
ENST00000538610.1
 PSMA5
 proteasome (prosome, macropain) subunit, alpha type, 5
chr19_+_42082506 0.12 ENST00000187608.9
ENST00000401445.2
 CEACAM21
 carcinoembryonic antigen-related cell adhesion molecule 21
chr1_+_169337172 0.12 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
 BLZF1
 basic leucine zipper nuclear factor 1
chr11_+_64323156 0.12 ENST00000377585.3
 SLC22A11
 solute carrier family 22 (organic anion/urate transporter), member 11
chr12_-_121019165 0.12 ENST00000341039.2
ENST00000357500.4
 POP5
 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
chr2_+_90248739 0.11 ENST00000468879.1
 IGKV1D-43
 immunoglobulin kappa variable 1D-43
chr6_-_41888843 0.11 ENST00000434077.1
ENST00000409312.1
 MED20
 mediator complex subunit 20
chrX_+_153409678 0.11 ENST00000369951.4
 OPN1LW
 opsin 1 (cone pigments), long-wave-sensitive
chr1_+_152658599 0.10 ENST00000368780.3
 LCE2B
 late cornified envelope 2B
chr18_-_54318353 0.10 ENST00000590954.1
ENST00000540155.1
 TXNL1
 thioredoxin-like 1
chr8_+_146277764 0.09 ENST00000331434.6
 C8orf33
 chromosome 8 open reading frame 33
chr21_+_38445539 0.09 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
 TTC3
 tetratricopeptide repeat domain 3
chr7_+_72742162 0.09 ENST00000431982.2
 FKBP6
 FK506 binding protein 6, 36kDa
chr22_+_44351301 0.09 ENST00000350028.4
 SAMM50
 SAMM50 sorting and assembly machinery component
chr9_-_123239632 0.09 ENST00000416449.1
 CDK5RAP2
 CDK5 regulatory subunit associated protein 2
chr11_-_1629693 0.09 ENST00000399685.1
 KRTAP5-3
 keratin associated protein 5-3
chr12_-_54070098 0.09 ENST00000394349.3
ENST00000549164.1
 ATP5G2
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr22_+_44351419 0.09 ENST00000396202.3
 SAMM50
 SAMM50 sorting and assembly machinery component
chr8_-_101734308 0.08 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
 PABPC1
 poly(A) binding protein, cytoplasmic 1
chr16_-_66968055 0.08 ENST00000568572.1
 FAM96B
 family with sequence similarity 96, member B
chr21_-_38445470 0.08 ENST00000399098.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr4_-_144826682 0.08 ENST00000358615.4
ENST00000437468.2
 GYPE
 glycophorin E (MNS blood group)
chr1_-_40237020 0.07 ENST00000327582.5
 OXCT2
 3-oxoacid CoA transferase 2
chr7_+_72742178 0.07 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
 FKBP6
 FK506 binding protein 6, 36kDa
chr11_-_71791518 0.07 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
 NUMA1
 nuclear mitotic apparatus protein 1
chr14_-_25103388 0.07 ENST00000526004.1
ENST00000415355.3
 GZMB
 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr2_+_90458201 0.06 ENST00000603238.1
 CH17-132F21.1
 Uncharacterized protein
chr13_-_108870623 0.06 ENST00000405925.1
 LIG4
 ligase IV, DNA, ATP-dependent
chr8_+_71581565 0.06 ENST00000408926.3
ENST00000520030.1
 XKR9
 XK, Kell blood group complex subunit-related family, member 9
chr2_-_89247338 0.06 ENST00000496168.1
 IGKV1-5
 immunoglobulin kappa variable 1-5
chr2_+_234216454 0.06 ENST00000447536.1
ENST00000409110.1
 SAG
 S-antigen; retina and pineal gland (arrestin)
chr3_+_148415571 0.06 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
 AGTR1
 angiotensin II receptor, type 1
chr6_-_29600832 0.05 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
 GABBR1
 gamma-aminobutyric acid (GABA) B receptor, 1
chr15_+_80364901 0.05 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr1_-_204165610 0.05 ENST00000367194.4
 KISS1
 KiSS-1 metastasis-suppressor
chr1_+_46016703 0.05 ENST00000481885.1
ENST00000351829.4
ENST00000471651.1
 AKR1A1
 aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr7_+_4815238 0.05 ENST00000348624.4
ENST00000401897.1
 AP5Z1
 adaptor-related protein complex 5, zeta 1 subunit
chr12_-_121476750 0.05 ENST00000543677.1
 OASL
 2'-5'-oligoadenylate synthetase-like
chr12_+_54379569 0.05 ENST00000513209.1
 RP11-834C11.12
 RP11-834C11.12
chrX_+_37850026 0.05 ENST00000341016.3
 CXorf27
 chromosome X open reading frame 27
chr4_-_48782259 0.04 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
 FRYL
 FRY-like
chr10_+_121652204 0.04 ENST00000369075.3
ENST00000543134.1
 SEC23IP
 SEC23 interacting protein
chr2_+_176957619 0.04 ENST00000392539.3
 HOXD13
 homeobox D13
chr3_+_155860751 0.04 ENST00000471742.1
 KCNAB1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr20_-_590944 0.03 ENST00000246080.3
 TCF15
 transcription factor 15 (basic helix-loop-helix)
chr1_+_3614591 0.03 ENST00000378290.4
 TP73
 tumor protein p73
chr10_+_26505594 0.03 ENST00000259271.3
 GAD2
 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr6_-_42981651 0.02 ENST00000244711.3
 MEA1
 male-enhanced antigen 1
chr7_-_99679324 0.02 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
 ZNF3
 zinc finger protein 3
chr1_-_31661000 0.02 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
 NKAIN1
 Na+/K+ transporting ATPase interacting 1
chr11_-_71791435 0.02 ENST00000351960.6
ENST00000541719.1
ENST00000535111.1
 NUMA1
 nuclear mitotic apparatus protein 1
chr18_-_18691739 0.02 ENST00000399799.2
 ROCK1
 Rho-associated, coiled-coil containing protein kinase 1
chr3_+_39851094 0.02 ENST00000302541.6
 MYRIP
 myosin VIIA and Rab interacting protein
chr20_+_35807449 0.02 ENST00000237530.6
 RPN2
 ribophorin II
chr1_+_45265897 0.02 ENST00000372201.4
 PLK3
 polo-like kinase 3
chr13_-_52378231 0.02 ENST00000280056.2
ENST00000444610.2
 DHRS12
 dehydrogenase/reductase (SDR family) member 12
chr14_-_25103472 0.02 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
 GZMB
 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_+_47799446 0.02 ENST00000371873.5
 CMPK1
 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr10_-_101380121 0.02 ENST00000370495.4
 SLC25A28
 solute carrier family 25 (mitochondrial iron transporter), member 28
chr1_-_20446020 0.01 ENST00000375105.3
 PLA2G2D
 phospholipase A2, group IID
chr2_-_89568263 0.01 ENST00000473726.1
 IGKV1-33
 immunoglobulin kappa variable 1-33
chr22_+_18632666 0.01 ENST00000215794.7
 USP18
 ubiquitin specific peptidase 18
chr22_+_19419425 0.01 ENST00000333130.3
 MRPL40
 mitochondrial ribosomal protein L40
chr3_-_42846021 0.01 ENST00000321331.7
 HIGD1A
 HIG1 hypoxia inducible domain family, member 1A
chr2_+_233320827 0.00 ENST00000295463.3
 ALPI
 alkaline phosphatase, intestinal
chr11_+_125774258 0.00 ENST00000263576.6
 DDX25
 DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr16_+_4784273 0.00 ENST00000299320.5
ENST00000586724.1
 C16orf71
 chromosome 16 open reading frame 71
chr21_-_38445011 0.00 ENST00000464265.1
ENST00000399102.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_109455845 0.00 ENST00000220853.3
 EMC2
 ER membrane protein complex subunit 2
chr21_+_34398153 0.00 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
 OLIG2
 oligodendrocyte lineage transcription factor 2
chrX_+_118602363 0.00 ENST00000317881.8
 SLC25A5
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr20_+_35807512 0.00 ENST00000373622.5
 RPN2
 ribophorin II
chr19_+_19496624 0.00 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
 GATAD2A
 GATA zinc finger domain containing 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 0.6 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.1 0.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 1.8 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.2 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 1.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 1.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.0 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.5 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0006909 phagocytosis(GO:0006909)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0043218 compact myelin(GO:0043218)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0061673 cortical microtubule(GO:0055028) mitotic spindle astral microtubule(GO:0061673)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.3 1.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.1 0.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events