ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HIF1A Links Ensembl NCBI GeneCards UniProt	ENSG00000100644.12	HIF1A

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HIF1A	hg19_v2_chr14_+_62162258_62162269	-0.19	4.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr7_+_26331541	2.22	ENST00000416246.1 ENST00000338523.4 ENST00000412416.1	SNX10	sorting nexin 10
chr7_+_128095945	2.12	ENST00000257696.4	HILPDA	hypoxia inducible lipid droplet-associated
chr14_+_64970662	1.84	ENST00000556965.1 ENST00000554015.1	ZBTB1	zinc finger and BTB domain containing 1
chr12_+_7023491	1.83	ENST00000541477.1 ENST00000229277.1	ENO2	enolase 2 (gamma, neuronal)
chr15_+_89181974	1.77	ENST00000306072.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr14_-_64970494	1.74	ENST00000608382.1	ZBTB25	zinc finger and BTB domain containing 25
chr15_+_89182178	1.73	ENST00000559876.1	ISG20	interferon stimulated exonuclease gene 20kDa
chr12_+_7023735	1.72	ENST00000538763.1 ENST00000544774.1 ENST00000545045.2	ENO2	enolase 2 (gamma, neuronal)
chr15_+_89182156	1.67	ENST00000379224.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr2_-_216946500	1.63	ENST00000265322.7	PECR	peroxisomal trans-2-enoyl-CoA reductase
chr1_+_65613852	1.63	ENST00000327299.7	AK4	adenylate kinase 4
chrX_+_24483338	1.60	ENST00000379162.4 ENST00000441463.2	PDK3	pyruvate dehydrogenase kinase, isozyme 3
chr15_-_60884706	1.59	ENST00000449337.2	RORA	RAR-related orphan receptor A
chr1_-_92351769	1.44	ENST00000212355.4	TGFBR3	transforming growth factor, beta receptor III
chr6_+_89791507	1.43	ENST00000354922.3	PNRC1	proline-rich nuclear receptor coactivator 1
chr11_+_7534999	1.37	ENST00000528947.1 ENST00000299492.4	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_88179302	1.29	ENST00000504921.2	MEF2C	myocyte enhancer factor 2C
chr12_+_6977258	1.24	ENST00000488464.2 ENST00000535434.1 ENST00000493987.1	TPI1	triosephosphate isomerase 1
chr19_+_41903709	1.18	ENST00000542943.1 ENST00000457836.2	BCKDHA	branched chain keto acid dehydrogenase E1, alpha polypeptide
chr5_-_88178964	1.14	ENST00000513252.1 ENST00000508569.1 ENST00000510942.1 ENST00000506554.1	MEF2C	myocyte enhancer factor 2C
chr3_-_195808952	1.10	ENST00000540528.1 ENST00000392396.3 ENST00000535031.1 ENST00000420415.1	TFRC	transferrin receptor
chr2_+_173420697	1.04	ENST00000282077.3 ENST00000392571.2 ENST00000410055.1	PDK1	pyruvate dehydrogenase kinase, isozyme 1
chr5_-_88179017	1.03	ENST00000514028.1 ENST00000514015.1 ENST00000503075.1 ENST00000437473.2	MEF2C	myocyte enhancer factor 2C
chr9_+_4490394	1.01	ENST00000262352.3	SLC1A1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr5_+_49962772	0.97	ENST00000281631.5 ENST00000513738.1 ENST00000503665.1 ENST00000514067.2 ENST00000503046.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr21_+_45719921	0.96	ENST00000349048.4	PFKL	phosphofructokinase, liver
chr3_-_195808980	0.96	ENST00000360110.4	TFRC	transferrin receptor
chr2_+_118846008	0.93	ENST00000245787.4	INSIG2	insulin induced gene 2
chr1_-_151319283	0.92	ENST00000392746.3	RFX5	regulatory factor X, 5 (influences HLA class II expression)
chr2_-_220083076	0.91	ENST00000295750.4	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr17_+_5185552	0.90	ENST00000262477.6 ENST00000408982.2 ENST00000575991.1 ENST00000537505.1 ENST00000546142.2	RABEP1	rabaptin, RAB GTPase binding effector protein 1
chr9_+_117373486	0.87	ENST00000288502.4 ENST00000374049.4	C9orf91	chromosome 9 open reading frame 91
chr15_+_41056255	0.85	ENST00000561160.1 ENST00000559445.1	GCHFR	GTP cyclohydrolase I feedback regulator
chr19_-_5719860	0.85	ENST00000590729.1	LONP1	lon peptidase 1, mitochondrial
chr6_-_153304148	0.84	ENST00000229758.3	FBXO5	F-box protein 5
chr2_-_214016314	0.82	ENST00000434687.1 ENST00000374319.4	IKZF2	IKAROS family zinc finger 2 (Helios)
chr15_+_41056218	0.81	ENST00000260447.4	GCHFR	GTP cyclohydrolase I feedback regulator
chr19_-_41903161	0.80	ENST00000602129.1 ENST00000593771.1 ENST00000596905.1 ENST00000221233.4	EXOSC5	exosome component 5
chr1_-_8939265	0.79	ENST00000489867.1	ENO1	enolase 1, (alpha)
chr1_-_32801825	0.79	ENST00000329421.7	MARCKSL1	MARCKS-like 1
chr19_-_5720123	0.78	ENST00000587365.1 ENST00000585374.1 ENST00000593119.1	LONP1	lon peptidase 1, mitochondrial
chr17_+_65373531	0.75	ENST00000580974.1	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1
chr20_+_30946106	0.71	ENST00000375687.4 ENST00000542461.1	ASXL1	additional sex combs like 1 (Drosophila)
chr8_+_98656336	0.71	ENST00000336273.3	MTDH	metadherin
chr19_-_5720248	0.69	ENST00000360614.3	LONP1	lon peptidase 1, mitochondrial
chr8_+_26240414	0.68	ENST00000380629.2	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr8_-_103424916	0.67	ENST00000220959.4	UBR5	ubiquitin protein ligase E3 component n-recognin 5
chr5_+_126112794	0.67	ENST00000261366.5 ENST00000395354.1	LMNB1	lamin B1
chr6_+_71377473	0.66	ENST00000370452.3 ENST00000316999.5 ENST00000370455.3	SMAP1	small ArfGAP 1
chr17_-_35969409	0.66	ENST00000394378.2 ENST00000585472.1 ENST00000591288.1 ENST00000502449.2 ENST00000345615.4 ENST00000346661.4 ENST00000585689.1 ENST00000339208.6	SYNRG	synergin, gamma
chr17_-_67323305	0.66	ENST00000392677.2 ENST00000593153.1	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5
chr8_-_103425047	0.65	ENST00000520539.1	UBR5	ubiquitin protein ligase E3 component n-recognin 5
chrX_+_77359726	0.64	ENST00000442431.1	PGK1	phosphoglycerate kinase 1
chr17_-_67323232	0.64	ENST00000592568.1 ENST00000392676.3	ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5
chr3_+_133292851	0.64	ENST00000503932.1	CDV3	CDV3 homolog (mouse)
chr6_-_153304697	0.63	ENST00000367241.3	FBXO5	F-box protein 5
chr6_-_112194484	0.63	ENST00000518295.1 ENST00000484067.2 ENST00000229470.5 ENST00000356013.2 ENST00000368678.4 ENST00000523238.1 ENST00000354650.3	FYN	FYN oncogene related to SRC, FGR, YES
chr8_+_98656693	0.61	ENST00000519934.1	MTDH	metadherin
chr17_+_80416482	0.61	ENST00000309794.11 ENST00000345415.7 ENST00000457415.3 ENST00000584411.1 ENST00000412079.2 ENST00000577432.1	NARF	nuclear prelamin A recognition factor
chr5_+_138609441	0.60	ENST00000509990.1 ENST00000506147.1 ENST00000512107.1	MATR3	matrin 3
chr8_-_103424986	0.60	ENST00000521922.1	UBR5	ubiquitin protein ligase E3 component n-recognin 5
chrX_+_77359671	0.59	ENST00000373316.4	PGK1	phosphoglycerate kinase 1
chr17_+_80416050	0.59	ENST00000579198.1 ENST00000390006.4 ENST00000580296.1	NARF	nuclear prelamin A recognition factor
chr15_+_74908147	0.58	ENST00000568139.1 ENST00000563297.1 ENST00000568488.1 ENST00000352989.5 ENST00000348245.3	CLK3	CDC-like kinase 3
chr2_+_88991162	0.58	ENST00000283646.4	RPIA	ribose 5-phosphate isomerase A
chr4_+_17578815	0.57	ENST00000226299.4	LAP3	leucine aminopeptidase 3
chr14_-_92572894	0.57	ENST00000532032.1 ENST00000506466.1 ENST00000555381.1 ENST00000557311.1 ENST00000554592.1 ENST00000554672.1 ENST00000553491.1 ENST00000556220.1 ENST00000502250.1 ENST00000503767.1 ENST00000393287.5 ENST00000340660.6 ENST00000545170.1 ENST00000429774.2	ATXN3	ataxin 3
chr7_+_116593433	0.57	ENST00000323984.3 ENST00000393449.1	ST7	suppression of tumorigenicity 7
chr12_+_72148614	0.56	ENST00000261263.3	RAB21	RAB21, member RAS oncogene family
chr19_-_49137790	0.55	ENST00000599385.1	DBP	D site of albumin promoter (albumin D-box) binding protein
chr13_+_103451399	0.55	ENST00000257336.1 ENST00000448849.2	BIVM	basic, immunoglobulin-like variable motif containing
chr2_+_204193149	0.53	ENST00000422511.2	ABI2	abl-interactor 2
chr7_+_94537542	0.51	ENST00000433881.1	PPP1R9A	protein phosphatase 1, regulatory subunit 9A
chr6_+_87865262	0.51	ENST00000369577.3 ENST00000518845.1 ENST00000339907.4 ENST00000496806.2	ZNF292	zinc finger protein 292
chr3_-_81811312	0.51	ENST00000429644.2	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr3_+_133292759	0.50	ENST00000431519.2	CDV3	CDV3 homolog (mouse)
chr17_-_74449252	0.50	ENST00000319380.7	UBE2O	ubiquitin-conjugating enzyme E2O
chr8_+_28351707	0.49	ENST00000537916.1 ENST00000523546.1 ENST00000240093.3	FZD3	frizzled family receptor 3
chr2_-_220083692	0.48	ENST00000265316.3	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr13_-_52027134	0.48	ENST00000311234.4 ENST00000425000.1 ENST00000463928.1 ENST00000442263.3 ENST00000398119.2	INTS6	integrator complex subunit 6
chr12_+_110906169	0.47	ENST00000377673.5	FAM216A	family with sequence similarity 216, member A
chr14_-_53162361	0.46	ENST00000395686.3	ERO1L	ERO1-like (S. cerevisiae)
chr5_+_49962495	0.46	ENST00000515175.1	PARP8	poly (ADP-ribose) polymerase family, member 8
chr1_+_112162381	0.45	ENST00000433097.1 ENST00000369709.3 ENST00000436150.2	RAP1A	RAP1A, member of RAS oncogene family
chr9_+_100745615	0.45	ENST00000339399.4	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_-_220083671	0.44	ENST00000439002.2	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr15_-_34875771	0.44	ENST00000267731.7	GOLGA8B	golgin A8 family, member B
chr12_+_6643676	0.41	ENST00000396856.1 ENST00000396861.1	GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr2_+_204192942	0.41	ENST00000295851.5 ENST00000261017.5	ABI2	abl-interactor 2
chrX_+_69509927	0.41	ENST00000374403.3	KIF4A	kinesin family member 4A
chr4_+_76649797	0.41	ENST00000538159.1 ENST00000514213.2	USO1	USO1 vesicle transport factor
chr6_+_108487245	0.40	ENST00000368986.4	NR2E1	nuclear receptor subfamily 2, group E, member 1
chr17_+_72428218	0.40	ENST00000392628.2	GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr2_+_204193129	0.40	ENST00000417864.1	ABI2	abl-interactor 2
chr6_+_64282447	0.39	ENST00000370650.2 ENST00000578299.1	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr1_-_8938736	0.38	ENST00000234590.4	ENO1	enolase 1, (alpha)
chr1_-_51425772	0.38	ENST00000371778.4	FAF1	Fas (TNFRSF6) associated factor 1
chr8_-_95908902	0.37	ENST00000520509.1	CCNE2	cyclin E2
chr19_-_49137762	0.37	ENST00000593500.1	DBP	D site of albumin promoter (albumin D-box) binding protein
chr11_-_57283159	0.36	ENST00000533263.1 ENST00000278426.3	SLC43A1	solute carrier family 43 (amino acid system L transporter), member 1
chr7_+_96747030	0.36	ENST00000360382.4	ACN9	ACN9 homolog (S. cerevisiae)
chr5_+_70883117	0.36	ENST00000340941.6	MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr12_-_121734489	0.35	ENST00000412367.2 ENST00000402834.4 ENST00000404169.3	CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta
chr11_-_118901559	0.35	ENST00000330775.7 ENST00000545985.1 ENST00000357590.5 ENST00000538950.1	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr3_+_184080790	0.34	ENST00000430783.1	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_45805667	0.34	ENST00000488731.2 ENST00000435155.1	MUTYH	mutY homolog
chr2_+_216176761	0.34	ENST00000540518.1 ENST00000435675.1	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_-_22396533	0.34	ENST00000344041.6	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr22_+_39853258	0.34	ENST00000341184.6	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_-_6259641	0.34	ENST00000234875.4	RPL22	ribosomal protein L22
chr5_+_70883178	0.34	ENST00000323375.8	MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr13_+_25875785	0.34	ENST00000381747.3	NUPL1	nucleoporin like 1
chr5_+_61602055	0.34	ENST00000381103.2	KIF2A	kinesin heavy chain member 2A
chr16_+_16043406	0.34	ENST00000399410.3 ENST00000399408.2 ENST00000346370.5 ENST00000351154.5 ENST00000345148.5 ENST00000349029.5	ABCC1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1
chr1_-_16678914	0.34	ENST00000375592.3	FBXO42	F-box protein 42
chr1_+_110162448	0.33	ENST00000342115.4 ENST00000469039.2 ENST00000474459.1 ENST00000528667.1	AMPD2	adenosine monophosphate deaminase 2
chr5_+_176853702	0.33	ENST00000507633.1 ENST00000393576.3 ENST00000355958.5 ENST00000528793.1 ENST00000512684.1	GRK6	G protein-coupled receptor kinase 6
chr1_+_231376941	0.32	ENST00000436239.1 ENST00000366647.4 ENST00000366646.3 ENST00000416000.1	GNPAT	glyceronephosphate O-acyltransferase
chr1_-_6269448	0.32	ENST00000465335.1	RPL22	ribosomal protein L22
chr12_+_6644443	0.32	ENST00000396858.1	GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr12_+_31477250	0.32	ENST00000313737.4	AC024940.1	AC024940.1
chr10_-_96122682	0.32	ENST00000371361.3	NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)
chr7_+_94536898	0.31	ENST00000433360.1 ENST00000340694.4 ENST00000424654.1	PPP1R9A	protein phosphatase 1, regulatory subunit 9A
chr2_+_216176540	0.31	ENST00000236959.9	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr14_+_77787227	0.31	ENST00000216465.5 ENST00000361389.4 ENST00000554279.1 ENST00000557639.1 ENST00000349555.3 ENST00000556627.1 ENST00000557053.1	GSTZ1	glutathione S-transferase zeta 1
chr1_-_45805607	0.31	ENST00000372104.1 ENST00000448481.1 ENST00000483127.1 ENST00000528013.2 ENST00000456914.2	MUTYH	mutY homolog
chr18_-_45457478	0.30	ENST00000402690.2 ENST00000356825.4	SMAD2	SMAD family member 2
chr3_-_49377499	0.30	ENST00000265560.4	USP4	ubiquitin specific peptidase 4 (proto-oncogene)
chr13_-_24463530	0.30	ENST00000382172.3	MIPEP	mitochondrial intermediate peptidase
chr15_-_74726283	0.30	ENST00000543145.2	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr8_+_17354587	0.29	ENST00000494857.1 ENST00000522656.1	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr7_-_139876812	0.28	ENST00000397560.2	JHDM1D	lysine (K)-specific demethylase 7A
chr19_+_38397839	0.28	ENST00000222345.6	SIPA1L3	signal-induced proliferation-associated 1 like 3
chr21_-_38639601	0.28	ENST00000539844.1 ENST00000476950.1 ENST00000399001.1	DSCR3	Down syndrome critical region gene 3
chr3_-_183543301	0.28	ENST00000318631.3 ENST00000431348.1	MAP6D1	MAP6 domain containing 1
chr12_-_49318715	0.28	ENST00000444214.2	FKBP11	FK506 binding protein 11, 19 kDa
chr6_-_151773232	0.28	ENST00000444024.1 ENST00000367303.4	RMND1	required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr6_+_35265586	0.27	ENST00000542066.1 ENST00000316637.5	DEF6	differentially expressed in FDCP 6 homolog (mouse)
chr8_+_17354617	0.27	ENST00000470360.1	SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_+_64281906	0.27	ENST00000370651.3	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr6_-_43021612	0.27	ENST00000535468.1	CUL7	cullin 7
chr3_-_49377446	0.27	ENST00000351842.4 ENST00000416417.1 ENST00000415188.1	USP4	ubiquitin specific peptidase 4 (proto-oncogene)
chr13_-_44361025	0.27	ENST00000261488.6	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr22_-_36903101	0.27	ENST00000397224.4	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr11_-_73471655	0.26	ENST00000400470.2	RAB6A	RAB6A, member RAS oncogene family
chr1_+_228353495	0.26	ENST00000366711.3	IBA57	IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr19_+_50180409	0.26	ENST00000391851.4	PRMT1	protein arginine methyltransferase 1
chr22_-_31741757	0.26	ENST00000215919.3	PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr1_-_6269304	0.25	ENST00000471204.1	RPL22	ribosomal protein L22
chr1_-_115053781	0.24	ENST00000358465.2 ENST00000369543.2	TRIM33	tripartite motif containing 33
chr7_-_92465868	0.24	ENST00000424848.2	CDK6	cyclin-dependent kinase 6
chr6_+_127588020	0.24	ENST00000309649.3 ENST00000610162.1 ENST00000610153.1 ENST00000608991.1 ENST00000480444.1	RNF146	ring finger protein 146
chr9_+_133884469	0.24	ENST00000361069.4	LAMC3	laminin, gamma 3
chr11_-_35440579	0.24	ENST00000606205.1	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_+_64564469	0.24	ENST00000373783.1	ADO	2-aminoethanethiol (cysteamine) dioxygenase
chr22_-_36903069	0.24	ENST00000216187.6 ENST00000423980.1	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr19_+_50180507	0.23	ENST00000454376.2 ENST00000524771.1	PRMT1	protein arginine methyltransferase 1
chr14_-_64010046	0.23	ENST00000337537.3	PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform
chr11_-_76155700	0.23	ENST00000572035.1	RP11-111M22.3	RP11-111M22.3
chr1_+_193091080	0.23	ENST00000367435.3	CDC73	cell division cycle 73
chr8_-_117768023	0.23	ENST00000518949.1 ENST00000522453.1 ENST00000521861.1 ENST00000518995.1	EIF3H	eukaryotic translation initiation factor 3, subunit H
chr22_+_24236191	0.22	ENST00000215754.7	MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr11_-_116968987	0.22	ENST00000434315.2 ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2	SIK3	SIK family kinase 3
chr7_+_128095900	0.22	ENST00000435296.2	HILPDA	hypoxia inducible lipid droplet-associated
chr9_-_139922631	0.21	ENST00000341511.6	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr11_+_73498898	0.21	ENST00000535529.1 ENST00000497094.2 ENST00000411840.2 ENST00000535277.1 ENST00000398483.3 ENST00000542303.1	MRPL48	mitochondrial ribosomal protein L48
chr17_+_25621102	0.20	ENST00000581440.1 ENST00000262394.2 ENST00000583742.1 ENST00000579733.1 ENST00000583193.1 ENST00000581185.1 ENST00000427287.2 ENST00000348811.2	WSB1	WD repeat and SOCS box containing 1
chr9_+_133569108	0.20	ENST00000372358.5 ENST00000546165.1 ENST00000372352.3 ENST00000372351.3 ENST00000372350.3 ENST00000495699.2	EXOSC2	exosome component 2
chr11_+_14665263	0.20	ENST00000282096.4	PDE3B	phosphodiesterase 3B, cGMP-inhibited
chr20_+_48552908	0.19	ENST00000244061.2	RNF114	ring finger protein 114
chr16_+_69166418	0.19	ENST00000314423.7 ENST00000562237.1 ENST00000567460.1 ENST00000566227.1 ENST00000352319.4 ENST00000563094.1	CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr2_+_32288725	0.19	ENST00000315285.3	SPAST	spastin
chr1_-_1709845	0.19	ENST00000341426.5 ENST00000344463.4	NADK	NAD kinase
chr11_-_35440796	0.19	ENST00000278379.3	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_-_39529180	0.18	ENST00000515021.1 ENST00000510490.1 ENST00000316423.6	UGDH	UDP-glucose 6-dehydrogenase
chr2_-_40006289	0.18	ENST00000260619.6 ENST00000454352.2	THUMPD2	THUMP domain containing 2
chr2_+_32288657	0.18	ENST00000345662.1	SPAST	spastin
chr12_-_113909877	0.17	ENST00000261731.3	LHX5	LIM homeobox 5
chrX_-_47509887	0.17	ENST00000247161.3 ENST00000592066.1 ENST00000376983.3	ELK1	ELK1, member of ETS oncogene family
chr11_-_18034701	0.17	ENST00000265965.5	SERGEF	secretion regulating guanine nucleotide exchange factor
chr8_-_30515693	0.17	ENST00000355904.4	GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa
chr8_-_101734907	0.17	ENST00000318607.5 ENST00000521865.1 ENST00000520804.1 ENST00000522720.1 ENST00000521067.1	PABPC1	poly(A) binding protein, cytoplasmic 1
chr14_-_23770683	0.16	ENST00000561437.1 ENST00000559942.1 ENST00000560913.1 ENST00000559314.1 ENST00000558058.1	PPP1R3E	protein phosphatase 1, regulatory subunit 3E
chr2_-_28113965	0.16	ENST00000302188.3	RBKS	ribokinase
chr17_+_76311791	0.16	ENST00000586321.1	AC061992.2	AC061992.2
chr1_-_6259613	0.16	ENST00000465387.1	RPL22	ribosomal protein L22
chr11_-_76155618	0.16	ENST00000530759.1	RP11-111M22.3	RP11-111M22.3
chr14_-_54908043	0.16	ENST00000556113.1 ENST00000553660.1 ENST00000395573.4 ENST00000557690.1 ENST00000216416.4	CNIH1	cornichon family AMPA receptor auxiliary protein 1
chr8_+_97274119	0.16	ENST00000455950.2	PTDSS1	phosphatidylserine synthase 1
chr4_+_78079450	0.16	ENST00000395640.1 ENST00000512918.1	CCNG2	cyclin G2
chr6_-_109702885	0.15	ENST00000504373.1	CD164	CD164 molecule, sialomucin
chr21_+_45138941	0.15	ENST00000398081.1 ENST00000468090.1 ENST00000291565.4	PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr11_-_100999775	0.14	ENST00000263463.5	PGR	progesterone receptor
chr4_-_39529049	0.14	ENST00000501493.2 ENST00000509391.1 ENST00000507089.1	UGDH	UDP-glucose 6-dehydrogenase
chr22_-_38577731	0.14	ENST00000335539.3	PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)
chr15_+_52311398	0.14	ENST00000261845.5	MAPK6	mitogen-activated protein kinase 6
chr16_+_53164833	0.14	ENST00000564845.1	CHD9	chromodomain helicase DNA binding protein 9
chr3_+_52719936	0.14	ENST00000418458.1 ENST00000394799.2	GNL3	guanine nucleotide binding protein-like 3 (nucleolar)
chr12_-_123849374	0.14	ENST00000602398.1 ENST00000602750.1	SBNO1	strawberry notch homolog 1 (Drosophila)
chr1_-_151319710	0.14	ENST00000290524.4 ENST00000437327.1 ENST00000452513.2 ENST00000368870.2 ENST00000452671.2	RFX5	regulatory factor X, 5 (influences HLA class II expression)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.7	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.4	2.2	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.4	1.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.3	1.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	1.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2	0.9	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	1.9	GO:0005638	lamin filament(GO:0005638)
0.2	1.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	1.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.2	2.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2	2.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.7	GO:1905202	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1	0.8	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.7	GO:0097452	GAIT complex(GO:0097452)
0.1	1.3	GO:0031209	SCAR complex(GO:0031209)
0.1	0.7	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.4	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.1	1.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	5.2	GO:0015030	Cajal body(GO:0015030)
0.1	0.7	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.1	0.3	GO:1990393	3M complex(GO:1990393)
0.1	0.5	GO:0032039	integrator complex(GO:0032039)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.3	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0036398	TCR signalosome(GO:0036398)
0.0	0.3	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.0	2.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.6	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.5	GO:0032433	filopodium tip(GO:0032433)
0.0	0.4	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	2.0	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	1.4	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:1990769	proximal neuron projection(GO:1990769)
0.0	0.3	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	4.6	GO:0016607	nuclear speck(GO:0016607)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	1.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.9	3.5	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.8	2.3	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.6	2.3	GO:0035425	autocrine signaling(GO:0035425)
0.6	1.7	GO:0043095	regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.5	1.5	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.5	1.4	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.5	1.8	GO:0002572	pro-T cell differentiation(GO:0002572)
0.4	1.2	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4	2.6	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3	1.0	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3	1.9	GO:0033183	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3	1.6	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.3	0.8	GO:0006014	D-ribose metabolic process(GO:0006014)
0.2	0.7	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	0.7	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2	0.8	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2	0.6	GO:1903401	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
0.2	1.4	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2	1.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2	1.2	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.2	1.8	GO:0015886	heme transport(GO:0015886)
0.2	0.5	GO:0045976	negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.2	1.6	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.2	0.7	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.2	0.5	GO:0097327	response to antineoplastic agent(GO:0097327)
0.1	0.6	GO:1904327	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	1.3	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	5.7	GO:0061718	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	1.8	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	0.7	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	2.1	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.3	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.3	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1	0.5	GO:0090237	regulation of arachidonic acid secretion(GO:0090237) positive regulation of arachidonic acid secretion(GO:0090238)
0.1	0.9	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.7	GO:0045007	depurination(GO:0045007)
0.1	2.2	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	0.3	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.1	0.7	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.3	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1	0.5	GO:0043985	histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653)
0.1	0.3	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.1	0.3	GO:0048511	rhythmic process(GO:0048511)
0.1	0.6	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.1	0.4	GO:0034214	protein hexamerization(GO:0034214) microtubule severing(GO:0051013)
0.1	0.3	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.3	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	1.3	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1	0.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125) minus-end-directed organelle transport along microtubule(GO:0072385)
0.1	1.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	0.2	GO:0042823	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.0	0.2	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.0	0.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.2	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.2	GO:0043697	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0	0.3	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0060748	paracrine signaling(GO:0038001) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0	0.6	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.3	GO:0032264	IMP salvage(GO:0032264)
0.0	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.5	GO:0016180	snRNA processing(GO:0016180)
0.0	0.3	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.2	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.4	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.7	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
0.0	0.1	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.0	0.1	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0	0.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0043335	protein unfolding(GO:0043335)
0.0	0.1	GO:0002840	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.2	GO:0001711	endodermal cell fate commitment(GO:0001711)
0.0	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	1.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.3	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.1	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
0.0	0.0	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.3	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.5	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.0	GO:0021784	postganglionic parasympathetic fiber development(GO:0021784)
0.0	0.7	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.4	GO:0007129	synapsis(GO:0007129)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.2	GO:0008859	exoribonuclease II activity(GO:0008859)
0.8	4.7	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.8	2.3	GO:0070361	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.7	2.1	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.7	2.6	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.6	1.8	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.6	1.7	GO:0044549	GTP cyclohydrolase binding(GO:0044549)
0.5	1.6	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4	1.2	GO:0004618	phosphoglycerate kinase activity(GO:0004618)
0.4	1.6	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4	1.2	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2	1.6	GO:0008142	oxysterol binding(GO:0008142)
0.2	1.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.2	3.5	GO:0003680	AT DNA binding(GO:0003680)
0.2	1.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.2	0.6	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.2	0.7	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2	1.8	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2	0.7	GO:0032406	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1	1.5	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1	1.4	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.6	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.7	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	1.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	0.3	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	0.3	GO:0015235	cobalamin transporter activity(GO:0015235)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.7	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.6	GO:0042610	CD8 receptor binding(GO:0042610)
0.1	2.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.1	1.8	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	0.7	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.2	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	0.5	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	0.2	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	1.9	GO:0005521	lamin binding(GO:0005521)
0.1	0.7	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.6	GO:1990380	Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1	0.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	1.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	1.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.3	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	1.0	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	1.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.3	GO:0016413	palmitoyl-CoA hydrolase activity(GO:0016290) O-acetyltransferase activity(GO:0016413)
0.0	0.7	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.6	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.0	0.2	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.7	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0030275	LRR domain binding(GO:0030275)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	6.8	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	2.0	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.7	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.3	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	1.9	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	2.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	3.6	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.7	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	1.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	5.2	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	1.5	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.0	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.6	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.7	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	1.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.9	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.7	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.9	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi