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ENCODE cell lines, expression (Ernst 2011)

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Results for HLF_TEF

Z-value: 0.57

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Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
HLF
ENSG00000108924.9 HLF
TEF
ENSG00000167074.10 TEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLFhg19_v2_chr17_+_53342311_53342400-0.263.3e-01Click!
TEFhg19_v2_chr22_+_41763274_41763337,
hg19_v2_chr22_+_41777927_41777971		-0.019.8e-01Click!

Activity profile of HLF_TEF motif

Sorted Z-values of HLF_TEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_158390282 2.78 ENST00000264265.3
 LXN
 latexin
chr3_-_99594948 1.19 ENST00000471562.1
ENST00000495625.2
 FILIP1L
 filamin A interacting protein 1-like
chr8_-_27469196 1.13 ENST00000546343.1
ENST00000560566.1
 CLU
 clusterin
chr3_-_99595037 1.11 ENST00000383694.2
 FILIP1L
 filamin A interacting protein 1-like
chr8_-_27468842 1.08 ENST00000523500.1
 CLU
 clusterin
chr8_-_27468945 1.08 ENST00000405140.3
 CLU
 clusterin
chr20_+_33759854 0.85 ENST00000216968.4
 PROCR
 protein C receptor, endothelial
chr5_-_111091948 0.82 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr3_+_157154578 0.82 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr13_-_38172863 0.64 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr1_-_244013384 0.62 ENST00000366539.1
 AKT3
 v-akt murine thymoma viral oncogene homolog 3
chr16_-_53537105 0.54 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
 AKTIP
 AKT interacting protein
chr14_-_23285011 0.50 ENST00000397532.3
 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_+_35201826 0.49 ENST00000531873.1
 CD44
 CD44 molecule (Indian blood group)
chr14_-_23285069 0.48 ENST00000554758.1
ENST00000397528.4
 SLC7A7
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_-_46459099 0.46 ENST00000371374.1
 RCAN2
 regulator of calcineurin 2
chr3_-_48130707 0.44 ENST00000360240.6
ENST00000383737.4
 MAP4
 microtubule-associated protein 4
chr10_-_14372870 0.42 ENST00000357447.2
 FRMD4A
 FERM domain containing 4A
chr3_+_158787041 0.41 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
chr20_-_33732952 0.40 ENST00000541621.1
 EDEM2
 ER degradation enhancer, mannosidase alpha-like 2
chr12_-_71031185 0.39 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr9_+_71820057 0.37 ENST00000539225.1
 TJP2
 tight junction protein 2
chr9_+_71819927 0.36 ENST00000535702.1
 TJP2
 tight junction protein 2
chr3_-_48130314 0.36 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
 MAP4
 microtubule-associated protein 4
chr21_+_27011584 0.35 ENST00000400532.1
ENST00000480456.1
ENST00000312957.5
 JAM2
 junctional adhesion molecule 2
chr3_+_62304712 0.34 ENST00000494481.1
 C3orf14
 chromosome 3 open reading frame 14
chr1_+_212738676 0.33 ENST00000366981.4
ENST00000366987.2
 ATF3
 activating transcription factor 3
chr5_-_54830871 0.33 ENST00000307259.8
 PPAP2A
 phosphatidic acid phosphatase type 2A
chr3_+_62304648 0.31 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
 C3orf14
 chromosome 3 open reading frame 14
chr5_+_34757309 0.30 ENST00000397449.1
 RAI14
 retinoic acid induced 14
chr2_-_203103185 0.29 ENST00000409205.1
 SUMO1
 small ubiquitin-like modifier 1
chr2_+_46769798 0.27 ENST00000238738.4
 RHOQ
 ras homolog family member Q
chr3_+_101504200 0.26 ENST00000422132.1
 NXPE3
 neurexophilin and PC-esterase domain family, member 3
chr8_+_70404996 0.26 ENST00000402687.4
ENST00000419716.3
 SULF1
 sulfatase 1
chr3_+_154797877 0.26 ENST00000462745.1
ENST00000493237.1
 MME
 membrane metallo-endopeptidase
chr17_-_34524157 0.26 ENST00000378354.4
ENST00000394484.1
 CCL3L3
 chemokine (C-C motif) ligand 3-like 3
chr15_-_66084428 0.25 ENST00000443035.3
ENST00000431932.2
 DENND4A
 DENN/MADD domain containing 4A
chr17_-_34625719 0.25 ENST00000422211.2
ENST00000542124.1
 CCL3L1
 chemokine (C-C motif) ligand 3-like 1
chr14_+_93260569 0.24 ENST00000163416.2
 GOLGA5
 golgin A5
chr12_-_71031220 0.24 ENST00000334414.6
 PTPRB
 protein tyrosine phosphatase, receptor type, B
chr14_+_93260642 0.22 ENST00000355976.2
 GOLGA5
 golgin A5
chr7_-_37026108 0.21 ENST00000396045.3
 ELMO1
 engulfment and cell motility 1
chr13_-_33780133 0.20 ENST00000399365.3
 STARD13
 StAR-related lipid transfer (START) domain containing 13
chr5_+_150404904 0.20 ENST00000521632.1
 GPX3
 glutathione peroxidase 3 (plasma)
chr14_+_96722152 0.19 ENST00000216629.6
 BDKRB1
 bradykinin receptor B1
chr5_-_138534071 0.19 ENST00000394817.2
 SIL1
 SIL1 nucleotide exchange factor
chr1_+_92632542 0.19 ENST00000409154.4
ENST00000370378.4
 KIAA1107
 KIAA1107
chr2_+_191208196 0.18 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
 INPP1
 inositol polyphosphate-1-phosphatase
chr9_-_88356789 0.18 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
 AGTPBP1
 ATP/GTP binding protein 1
chr4_+_157997273 0.18 ENST00000541722.1
ENST00000512619.1
 GLRB
 glycine receptor, beta
chr18_+_32621324 0.17 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
chr9_+_101705893 0.17 ENST00000375001.3
 COL15A1
 collagen, type XV, alpha 1
chr2_-_99279928 0.16 ENST00000414521.2
 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_-_76928641 0.15 ENST00000264888.5
 CXCL9
 chemokine (C-X-C motif) ligand 9
chr7_-_83824169 0.15 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_+_52076425 0.15 ENST00000436511.2
 ZNF175
 zinc finger protein 175
chr9_-_88356733 0.15 ENST00000376083.3
 AGTPBP1
 ATP/GTP binding protein 1
chr5_-_138533973 0.14 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
 SIL1
 SIL1 nucleotide exchange factor
chr14_+_96722539 0.14 ENST00000553356.1
 BDKRB1
 bradykinin receptor B1
chr17_+_73089382 0.14 ENST00000538213.2
ENST00000584118.1
 SLC16A5
 solute carrier family 16 (monocarboxylate transporter), member 5
chr1_+_169079823 0.13 ENST00000367813.3
 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
chr22_+_41487711 0.13 ENST00000263253.7
 EP300
 E1A binding protein p300
chr13_-_29292956 0.13 ENST00000266943.6
 SLC46A3
 solute carrier family 46, member 3
chr17_+_39975455 0.13 ENST00000455106.1
 FKBP10
 FK506 binding protein 10, 65 kDa
chr10_+_94050913 0.13 ENST00000358935.2
 MARCH5
 membrane-associated ring finger (C3HC4) 5
chr19_+_49259325 0.12 ENST00000222157.3
 FGF21
 fibroblast growth factor 21
chr19_+_50922187 0.12 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
 SPIB
 Spi-B transcription factor (Spi-1/PU.1 related)
chr9_+_124103625 0.12 ENST00000594963.1
 AL161784.1
 Uncharacterized protein
chr3_-_58200398 0.12 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
 DNASE1L3
 deoxyribonuclease I-like 3
chr2_-_98280383 0.12 ENST00000289228.5
 ACTR1B
 ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr20_-_49547910 0.11 ENST00000396032.3
 ADNP
 activity-dependent neuroprotector homeobox
chr19_+_49258775 0.11 ENST00000593756.1
 FGF21
 fibroblast growth factor 21
chr2_+_198318147 0.11 ENST00000263960.2
 COQ10B
 coenzyme Q10 homolog B (S. cerevisiae)
chr19_+_41594377 0.10 ENST00000330436.3
 CYP2A13
 cytochrome P450, family 2, subfamily A, polypeptide 13
chr1_-_203155868 0.10 ENST00000255409.3
 CHI3L1
 chitinase 3-like 1 (cartilage glycoprotein-39)
chr14_+_60716159 0.09 ENST00000325658.3
 PPM1A
 protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr8_-_103425047 0.09 ENST00000520539.1
 UBR5
 ubiquitin protein ligase E3 component n-recognin 5
chr11_-_77185094 0.08 ENST00000278568.4
ENST00000356341.3
 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
chr13_-_45010939 0.08 ENST00000261489.2
 TSC22D1
 TSC22 domain family, member 1
chr5_+_49963239 0.08 ENST00000505554.1
 PARP8
 poly (ADP-ribose) polymerase family, member 8
chr10_+_18629628 0.08 ENST00000377329.4
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr14_-_67826486 0.07 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
 ATP6V1D
 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr5_+_95997918 0.07 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
 CAST
 calpastatin
chr22_-_30867973 0.07 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
 SEC14L3
 SEC14-like 3 (S. cerevisiae)
chr16_+_56965960 0.07 ENST00000439977.2
ENST00000344114.4
ENST00000300302.5
ENST00000379792.2
 HERPUD1
 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr7_+_100210133 0.07 ENST00000393950.2
ENST00000424091.2
 MOSPD3
 motile sperm domain containing 3
chr5_+_95997769 0.07 ENST00000338252.3
ENST00000508830.1
 CAST
 calpastatin
chr3_+_169684553 0.07 ENST00000337002.4
ENST00000480708.1
 SEC62
 SEC62 homolog (S. cerevisiae)
chr21_+_19617140 0.06 ENST00000299295.2
ENST00000338326.3
 CHODL
 chondrolectin
chr20_-_49547731 0.06 ENST00000396029.3
 ADNP
 activity-dependent neuroprotector homeobox
chr3_-_45883558 0.06 ENST00000445698.1
ENST00000296135.6
 LZTFL1
 leucine zipper transcription factor-like 1
chr18_+_77160282 0.06 ENST00000318065.5
ENST00000545796.1
ENST00000592223.1
ENST00000329101.4
ENST00000586434.1
 NFATC1
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr10_-_65028938 0.06 ENST00000402544.1
 JMJD1C
 jumonji domain containing 1C
chr11_-_14993819 0.06 ENST00000396372.2
ENST00000361010.3
ENST00000359642.3
ENST00000331587.4
 CALCA
 calcitonin-related polypeptide alpha
chr5_-_43557791 0.06 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
 PAIP1
 poly(A) binding protein interacting protein 1
chr8_+_90914073 0.06 ENST00000297438.2
 OSGIN2
 oxidative stress induced growth inhibitor family member 2
chr17_+_61851157 0.06 ENST00000578681.1
ENST00000583590.1
 DDX42
 DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr1_+_161087873 0.05 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
 NIT1
 nitrilase 1
chr13_-_46626847 0.05 ENST00000242848.4
ENST00000282007.3
 ZC3H13
 zinc finger CCCH-type containing 13
chr15_+_49913201 0.05 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
 DTWD1
 DTW domain containing 1
chr17_-_73179046 0.05 ENST00000314523.7
ENST00000420826.2
 SUMO2
 small ubiquitin-like modifier 2
chr8_-_103424986 0.05 ENST00000521922.1
 UBR5
 ubiquitin protein ligase E3 component n-recognin 5
chr16_+_70332956 0.05 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
 DDX19B
RP11-529K1.3
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr12_-_101801505 0.05 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
 ARL1
 ADP-ribosylation factor-like 1
chr5_+_95998070 0.04 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
 CAST
 calpastatin
chr11_-_33913708 0.04 ENST00000257818.2
 LMO2
 LIM domain only 2 (rhombotin-like 1)
chr11_-_102576537 0.04 ENST00000260229.4
 MMP27
 matrix metallopeptidase 27
chr5_-_147162263 0.04 ENST00000333010.6
ENST00000265272.5
 JAKMIP2
 janus kinase and microtubule interacting protein 2
chr17_-_73178599 0.04 ENST00000578238.1
 SUMO2
 small ubiquitin-like modifier 2
chr10_-_65028817 0.04 ENST00000542921.1
 JMJD1C
 jumonji domain containing 1C
chr3_+_88188254 0.03 ENST00000309495.5
 ZNF654
 zinc finger protein 654
chr7_+_44646177 0.03 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr6_+_36238237 0.03 ENST00000457797.1
ENST00000394571.2
 PNPLA1
 patatin-like phospholipase domain containing 1
chr8_-_103424916 0.03 ENST00000220959.4
 UBR5
 ubiquitin protein ligase E3 component n-recognin 5
chr8_-_37824442 0.03 ENST00000345060.3
 ADRB3
 adrenoceptor beta 3
chr17_-_73851285 0.03 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
 WBP2
 WW domain binding protein 2
chr19_-_41945804 0.03 ENST00000221943.9
ENST00000597457.1
ENST00000589970.1
ENST00000595425.1
ENST00000438807.3
ENST00000589102.1
ENST00000592922.2
 ATP5SL
 ATP5S-like
chr14_+_102276192 0.03 ENST00000557714.1
 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
chr7_-_22259845 0.03 ENST00000420196.1
 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
chr9_-_95298314 0.03 ENST00000344604.5
ENST00000375540.1
 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
chr4_-_96470350 0.02 ENST00000504962.1
ENST00000453304.1
ENST00000506749.1
 UNC5C
 unc-5 homolog C (C. elegans)
chr8_+_107738240 0.02 ENST00000449762.2
ENST00000297447.6
 OXR1
 oxidation resistance 1
chr11_-_62313090 0.02 ENST00000528508.1
ENST00000533365.1
 AHNAK
 AHNAK nucleoprotein
chr1_+_115572415 0.02 ENST00000256592.1
 TSHB
 thyroid stimulating hormone, beta
chr2_-_100106419 0.02 ENST00000393445.3
ENST00000258428.3
 REV1
 REV1, polymerase (DNA directed)
chr7_+_20686946 0.02 ENST00000443026.2
ENST00000406935.1
 ABCB5
 ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_-_161207875 0.02 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr2_-_167232484 0.02 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A
 sodium channel, voltage-gated, type IX, alpha subunit
chr8_+_24298531 0.02 ENST00000175238.6
 ADAM7
 ADAM metallopeptidase domain 7
chr18_+_3262954 0.02 ENST00000584539.1
 MYL12B
 myosin, light chain 12B, regulatory
chr17_-_41984835 0.02 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
 MPP2
 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_+_94752349 0.02 ENST00000391680.1
 RBM12B-AS1
 RBM12B antisense RNA 1
chr11_+_123986069 0.01 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
 VWA5A
 von Willebrand factor A domain containing 5A
chr1_-_161208013 0.01 ENST00000515452.1
ENST00000367983.4
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr16_+_56899114 0.01 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
 SLC12A3
 solute carrier family 12 (sodium/chloride transporter), member 3
chr8_-_6735451 0.01 ENST00000297439.3
 DEFB1
 defensin, beta 1
chr1_-_161207953 0.01 ENST00000367982.4
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr12_-_53074182 0.01 ENST00000252244.3
 KRT1
 keratin 1
chr16_-_30102547 0.01 ENST00000279386.2
 TBX6
 T-box 6
chr15_+_58430368 0.00 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr11_-_33795893 0.00 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
 FBXO3
 F-box protein 3
chr22_-_29711704 0.00 ENST00000216101.6
 RASL10A
 RAS-like, family 10, member A
chr1_-_161207986 0.00 ENST00000506209.1
ENST00000367980.2
 NR1I3
 nuclear receptor subfamily 1, group I, member 3
chr3_+_186383741 0.00 ENST00000232003.4
 HRG
 histidine-rich glycoprotein
chr10_-_97416400 0.00 ENST00000371224.2
ENST00000371221.3
 ALDH18A1
 aldehyde dehydrogenase 18 family, member A1
chr6_-_116447283 0.00 ENST00000452729.1
ENST00000243222.4
 COL10A1
 collagen, type X, alpha 1
chr14_-_70263979 0.00 ENST00000216540.4
 SLC10A1
 solute carrier family 10 (sodium/bile acid cotransporter), member 1

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 2.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.6 GO:1990523 bone regeneration(GO:1990523)
0.2 0.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 1.0 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 2.8 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.2 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0048880 sensory system development(GO:0048880)
0.0 0.3 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.5 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.8 GO:0050819 negative regulation of coagulation(GO:0050819)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 3.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events