ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
HMBOX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000147421.13	HMBOX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMBOX1	hg19_v2_chr8_+_28748099_28748142, hg19_v2_chr8_+_28748765_28748833	-0.08	7.8e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr3_-_149095652	4.40	ENST00000305366.3	TM4SF1	transmembrane 4 L six family member 1
chr1_-_173176452	2.54	ENST00000281834.3	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4
chr10_+_89419370	2.53	ENST00000361175.4 ENST00000456849.1	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_19798964	2.11	ENST00000527559.2	NAV2	neuron navigator 2
chr8_+_30244580	2.05	ENST00000523115.1 ENST00000519647.1	RBPMS	RNA binding protein with multiple splicing
chr7_-_47579188	2.01	ENST00000398879.1 ENST00000355730.3 ENST00000442536.2 ENST00000458317.2	TNS3	tensin 3
chrX_-_10851762	1.98	ENST00000380785.1 ENST00000380787.1	MID1	midline 1 (Opitz/BBB syndrome)
chr4_-_114900831	1.90	ENST00000315366.7	ARSJ	arylsulfatase family, member J
chr12_-_77272765	1.66	ENST00000547435.1 ENST00000552330.1 ENST00000546966.1 ENST00000311083.5	CSRP2	cysteine and glycine-rich protein 2
chr7_-_120498357	1.60	ENST00000415871.1 ENST00000222747.3 ENST00000430985.1	TSPAN12	tetraspanin 12
chr12_+_75874580	1.54	ENST00000456650.3	GLIPR1	GLI pathogenesis-related 1
chrX_-_21776281	1.47	ENST00000379494.3	SMPX	small muscle protein, X-linked
chr20_+_43211149	1.47	ENST00000372886.1	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chrX_-_10588459	1.41	ENST00000380782.2	MID1	midline 1 (Opitz/BBB syndrome)
chr5_+_92919043	1.40	ENST00000327111.3	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr1_-_110283138	1.39	ENST00000256594.3	GSTM3	glutathione S-transferase mu 3 (brain)
chr7_+_134576317	1.39	ENST00000424922.1 ENST00000495522.1	CALD1	caldesmon 1
chr17_-_3571934	1.38	ENST00000225525.3	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chrX_-_10588595	1.35	ENST00000423614.1 ENST00000317552.4	MID1	midline 1 (Opitz/BBB syndrome)
chr8_-_38326119	1.34	ENST00000356207.5 ENST00000326324.6	FGFR1	fibroblast growth factor receptor 1
chr1_+_84609944	1.28	ENST00000370685.3	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr8_-_38326139	1.26	ENST00000335922.5 ENST00000532791.1 ENST00000397091.5	FGFR1	fibroblast growth factor receptor 1
chrX_+_66764375	1.26	ENST00000374690.3	AR	androgen receptor
chr9_+_75766652	1.25	ENST00000257497.6	ANXA1	annexin A1
chr18_-_53253323	1.16	ENST00000540999.1 ENST00000563888.2	TCF4	transcription factor 4
chrX_+_37208540	1.14	ENST00000466533.1 ENST00000542554.1 ENST00000543642.1 ENST00000484460.1 ENST00000449135.2 ENST00000463135.1 ENST00000465127.1	PRRG1 TM4SF2	proline rich Gla (G-carboxyglutamic acid) 1 Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr7_+_134576151	1.12	ENST00000393118.2	CALD1	caldesmon 1
chr8_-_67525473	1.10	ENST00000522677.3	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1
chrX_+_37208521	1.09	ENST00000378628.4	PRRG1	proline rich Gla (G-carboxyglutamic acid) 1
chr4_-_186877502	1.08	ENST00000431902.1 ENST00000284776.7 ENST00000415274.1	SORBS2	sorbin and SH3 domain containing 2
chr1_-_201346761	0.95	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2	troponin T type 2 (cardiac)
chr1_-_152009460	0.90	ENST00000271638.2	S100A11	S100 calcium binding protein A11
chr20_+_61584026	0.89	ENST00000370351.4 ENST00000370349.3	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9
chr9_-_73029540	0.89	ENST00000377126.2	KLF9	Kruppel-like factor 9
chr7_+_128379449	0.87	ENST00000479257.1	CALU	calumenin
chr8_+_27491572	0.82	ENST00000301904.3	SCARA3	scavenger receptor class A, member 3
chr19_+_16178317	0.77	ENST00000344824.6 ENST00000538887.1	TPM4	tropomyosin 4
chr17_-_1395954	0.74	ENST00000359786.5	MYO1C	myosin IC
chr14_+_45431379	0.68	ENST00000361577.3 ENST00000361462.2 ENST00000382233.2	FAM179B	family with sequence similarity 179, member B
chr5_-_77844974	0.63	ENST00000515007.2	LHFPL2	lipoma HMGIC fusion partner-like 2
chr13_-_67802549	0.62	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr4_-_110723194	0.61	ENST00000394635.3	CFI	complement factor I
chr12_+_81101277	0.58	ENST00000228641.3	MYF6	myogenic factor 6 (herculin)
chr22_-_37880543	0.56	ENST00000442496.1	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_52628271	0.55	ENST00000493422.1	GSTA2	glutathione S-transferase alpha 2
chr4_-_110723134	0.52	ENST00000510800.1 ENST00000512148.1	CFI	complement factor I
chr22_-_37172111	0.52	ENST00000417951.2 ENST00000430701.1 ENST00000433985.2	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)
chr6_-_165989936	0.52	ENST00000354448.4	PDE10A	phosphodiesterase 10A
chr5_+_140762268	0.51	ENST00000518325.1	PCDHGA7	protocadherin gamma subfamily A, 7
chr3_+_147127142	0.50	ENST00000282928.4	ZIC1	Zic family member 1
chr22_-_37172191	0.49	ENST00000340630.5	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)
chr5_+_140810132	0.48	ENST00000252085.3	PCDHGA12	protocadherin gamma subfamily A, 12
chr6_+_46097711	0.47	ENST00000321037.4	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr3_+_33155444	0.47	ENST00000320954.6	CRTAP	cartilage associated protein
chr10_+_124320195	0.47	ENST00000359586.6	DMBT1	deleted in malignant brain tumors 1
chr12_-_56236734	0.47	ENST00000548629.1	MMP19	matrix metallopeptidase 19
chr19_-_19051103	0.46	ENST00000542541.2 ENST00000433218.2	HOMER3	homer homolog 3 (Drosophila)
chr3_+_101504200	0.44	ENST00000422132.1	NXPE3	neurexophilin and PC-esterase domain family, member 3
chr3_-_69101461	0.41	ENST00000543976.1	TMF1	TATA element modulatory factor 1
chrX_+_70586140	0.41	ENST00000276072.3	TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr12_+_54674482	0.41	ENST00000547708.1 ENST00000340913.6 ENST00000551702.1 ENST00000330752.8 ENST00000547276.1	HNRNPA1	heterogeneous nuclear ribonucleoprotein A1
chr17_-_10452929	0.41	ENST00000532183.2 ENST00000397183.2 ENST00000420805.1	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr10_-_112678976	0.40	ENST00000448814.1	BBIP1	BBSome interacting protein 1
chr6_-_52710893	0.40	ENST00000284562.2	GSTA5	glutathione S-transferase alpha 5
chr2_+_162087577	0.39	ENST00000439442.1	TANK	TRAF family member-associated NFKB activator
chr1_+_87595433	0.38	ENST00000469312.2 ENST00000490006.2	RP5-1052I5.1	long intergenic non-protein coding RNA 1140
chr11_-_59950519	0.37	ENST00000528851.1	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A
chr11_-_59950622	0.37	ENST00000323961.3 ENST00000412309.2	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A
chr1_+_198126093	0.36	ENST00000367385.4 ENST00000442588.1 ENST00000538004.1	NEK7	NIMA-related kinase 7
chr10_-_112678904	0.36	ENST00000423273.1 ENST00000436562.1 ENST00000447005.1 ENST00000454061.1	BBIP1	BBSome interacting protein 1
chr11_-_64825993	0.34	ENST00000340252.4 ENST00000355721.3 ENST00000356632.3 ENST00000355369.2 ENST00000339885.2 ENST00000358658.3	NAALADL1	N-acetylated alpha-linked acidic dipeptidase-like 1
chr14_-_50999307	0.34	ENST00000013125.4	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5
chr3_+_33155525	0.34	ENST00000449224.1	CRTAP	cartilage associated protein
chr2_+_24714729	0.33	ENST00000406961.1 ENST00000405141.1	NCOA1	nuclear receptor coactivator 1
chr6_-_52668605	0.32	ENST00000334575.5	GSTA1	glutathione S-transferase alpha 1
chr3_-_69101413	0.32	ENST00000398559.2	TMF1	TATA element modulatory factor 1
chrX_-_153523462	0.31	ENST00000361930.3 ENST00000369926.1	TEX28	testis expressed 28
chr20_-_43133491	0.30	ENST00000411544.1	SERINC3	serine incorporator 3
chr4_-_159080806	0.29	ENST00000590648.1	FAM198B	family with sequence similarity 198, member B
chr6_+_138725343	0.29	ENST00000607197.1 ENST00000367697.3	HEBP2	heme binding protein 2
chr12_-_54673871	0.28	ENST00000209875.4	CBX5	chromobox homolog 5
chr2_-_99952769	0.28	ENST00000409434.1 ENST00000434323.1 ENST00000264255.3	TXNDC9	thioredoxin domain containing 9
chr2_+_27994567	0.27	ENST00000379666.3 ENST00000296102.3	MRPL33	mitochondrial ribosomal protein L33
chr15_+_79166065	0.26	ENST00000559690.1 ENST00000559158.1	MORF4L1	mortality factor 4 like 1
chr11_-_59950486	0.26	ENST00000426738.2 ENST00000533023.1 ENST00000420732.2	MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A
chr2_+_128848740	0.24	ENST00000375990.3	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1
chr14_+_22615942	0.24	ENST00000390457.2	TRAV27	T cell receptor alpha variable 27
chr8_-_63951730	0.24	ENST00000260118.6	GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr2_-_220110111	0.23	ENST00000428427.1 ENST00000356283.3 ENST00000432839.1 ENST00000424620.1	GLB1L	galactosidase, beta 1-like
chr3_+_69928256	0.23	ENST00000394355.2	MITF	microphthalmia-associated transcription factor
chr11_+_64692143	0.23	ENST00000164133.2 ENST00000532850.1	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr8_+_94929969	0.23	ENST00000517764.1	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr14_+_105331596	0.22	ENST00000556508.1 ENST00000414716.3 ENST00000453495.1 ENST00000418279.1	CEP170B	centrosomal protein 170B
chr16_-_71842941	0.21	ENST00000423132.2 ENST00000433195.2 ENST00000569748.1 ENST00000570017.1	AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr2_+_204193149	0.21	ENST00000422511.2	ABI2	abl-interactor 2
chr6_-_31940065	0.20	ENST00000375349.3 ENST00000337523.5	DXO	decapping exoribonuclease
chr8_+_120885949	0.18	ENST00000523492.1 ENST00000286234.5	DEPTOR	DEP domain containing MTOR-interacting protein
chrX_+_70586082	0.18	ENST00000373790.4 ENST00000449580.1 ENST00000423759.1	TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr17_+_48172639	0.17	ENST00000503176.1 ENST00000503614.1	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr1_+_206643787	0.16	ENST00000367120.3	IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr1_+_196743943	0.16	ENST00000471440.2 ENST00000391985.3	CFHR3	complement factor H-related 3
chr2_+_204193101	0.16	ENST00000430418.1 ENST00000424558.1 ENST00000261016.6	ABI2	abl-interactor 2
chr12_+_72080253	0.16	ENST00000549735.1	TMEM19	transmembrane protein 19
chr2_+_204193129	0.15	ENST00000417864.1	ABI2	abl-interactor 2
chr11_+_1860832	0.15	ENST00000252898.7	TNNI2	troponin I type 2 (skeletal, fast)
chr11_-_47447970	0.15	ENST00000298852.3 ENST00000530912.1	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr6_-_117747015	0.15	ENST00000368508.3 ENST00000368507.3	ROS1	c-ros oncogene 1 , receptor tyrosine kinase
chr7_+_101460882	0.15	ENST00000292535.7 ENST00000549414.2 ENST00000550008.2 ENST00000546411.2 ENST00000556210.1	CUX1	cut-like homeobox 1
chr12_-_25348007	0.15	ENST00000354189.5 ENST00000545133.1 ENST00000554347.1 ENST00000395987.3 ENST00000320267.9 ENST00000395990.2 ENST00000537577.1	CASC1	cancer susceptibility candidate 1
chr16_+_28835437	0.15	ENST00000568266.1	ATXN2L	ataxin 2-like
chr4_+_74301880	0.15	ENST00000395792.2 ENST00000226359.2	AFP	alpha-fetoprotein
chr4_-_10117949	0.14	ENST00000508079.1	WDR1	WD repeat domain 1
chr11_+_65769550	0.14	ENST00000312175.2 ENST00000445560.2 ENST00000530204.1	BANF1	barrier to autointegration factor 1
chr1_+_89246647	0.14	ENST00000544045.1	PKN2	protein kinase N2
chr16_-_71843047	0.14	ENST00000299980.4 ENST00000393512.3	AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr3_-_45837959	0.13	ENST00000353278.4 ENST00000456124.2	SLC6A20	solute carrier family 6 (proline IMINO transporter), member 20
chr13_-_77901177	0.13	ENST00000407578.2 ENST00000357337.6 ENST00000360084.5	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase
chr2_-_220110187	0.13	ENST00000295759.7 ENST00000392089.2	GLB1L	galactosidase, beta 1-like
chr15_+_75639296	0.13	ENST00000564500.1 ENST00000355059.4 ENST00000566752.1	NEIL1	nei endonuclease VIII-like 1 (E. coli)
chr1_-_169396666	0.12	ENST00000456107.1 ENST00000367805.3	CCDC181	coiled-coil domain containing 181
chr1_-_169396646	0.12	ENST00000367806.3	CCDC181	coiled-coil domain containing 181
chr8_-_101734170	0.12	ENST00000522387.1 ENST00000518196.1	PABPC1	poly(A) binding protein, cytoplasmic 1
chr5_+_176560742	0.12	ENST00000439151.2	NSD1	nuclear receptor binding SET domain protein 1
chr4_+_156824840	0.11	ENST00000536354.2	TDO2	tryptophan 2,3-dioxygenase
chr19_+_42300548	0.11	ENST00000344550.4	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3
chr19_+_55014085	0.11	ENST00000351841.2	LAIR2	leukocyte-associated immunoglobulin-like receptor 2
chr5_+_176561129	0.10	ENST00000511258.1 ENST00000347982.4	NSD1	nuclear receptor binding SET domain protein 1
chr3_-_45838011	0.10	ENST00000358525.4 ENST00000413781.1	SLC6A20	solute carrier family 6 (proline IMINO transporter), member 20
chr19_+_7599128	0.09	ENST00000545201.2	PNPLA6	patatin-like phospholipase domain containing 6
chr1_-_150669500	0.09	ENST00000271732.3	GOLPH3L	golgi phosphoprotein 3-like
chr4_-_69434245	0.09	ENST00000317746.2	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17
chr19_+_55014013	0.09	ENST00000301202.2	LAIR2	leukocyte-associated immunoglobulin-like receptor 2
chr3_-_49142504	0.08	ENST00000306125.6 ENST00000420147.2	QARS	glutaminyl-tRNA synthetase
chr7_+_107220899	0.08	ENST00000379117.2 ENST00000473124.1	BCAP29	B-cell receptor-associated protein 29
chr1_-_203274418	0.07	ENST00000457348.1	RP11-134P9.1	long intergenic non-protein coding RNA 1136
chr17_-_3195876	0.07	ENST00000323404.1	OR3A1	olfactory receptor, family 3, subfamily A, member 1
chr8_-_27630102	0.07	ENST00000356537.4 ENST00000522915.1 ENST00000539095.1	CCDC25	coiled-coil domain containing 25
chr13_-_108870623	0.07	ENST00000405925.1	LIG4	ligase IV, DNA, ATP-dependent
chr12_+_117013656	0.06	ENST00000556529.1	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2
chr22_-_36635684	0.06	ENST00000358502.5	APOL2	apolipoprotein L, 2
chr19_+_50353944	0.06	ENST00000594151.1 ENST00000600603.1 ENST00000601638.1 ENST00000221557.9	PTOV1	prostate tumor overexpressed 1
chr14_-_89878369	0.06	ENST00000553840.1 ENST00000556916.1	FOXN3	forkhead box N3
chr16_-_67281413	0.06	ENST00000258201.4	FHOD1	formin homology 2 domain containing 1
chr1_+_27561104	0.06	ENST00000361771.3	WDTC1	WD and tetratricopeptide repeats 1
chr1_+_207943667	0.05	ENST00000462968.2	CD46	CD46 molecule, complement regulatory protein
chr1_+_196743912	0.05	ENST00000367425.4	CFHR3	complement factor H-related 3
chr19_+_38826477	0.05	ENST00000409410.2 ENST00000215069.4	CATSPERG	catsper channel auxiliary subunit gamma
chr20_+_42187682	0.05	ENST00000373092.3 ENST00000373077.1	SGK2	serum/glucocorticoid regulated kinase 2
chr4_+_74347400	0.05	ENST00000226355.3	AFM	afamin
chr19_+_38826415	0.04	ENST00000410018.1 ENST00000409235.3	CATSPERG	catsper channel auxiliary subunit gamma
chr1_+_207226574	0.04	ENST00000367080.3 ENST00000367079.2	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr6_+_96969672	0.03	ENST00000369278.4	UFL1	UFM1-specific ligase 1
chr22_+_24200085	0.03	ENST00000316185.8	SLC2A11	solute carrier family 2 (facilitated glucose transporter), member 11
chr2_+_220110177	0.03	ENST00000409638.3 ENST00000396738.2 ENST00000409516.3	STK16	serine/threonine kinase 16
chr10_+_112679301	0.03	ENST00000265277.5 ENST00000369452.4	SHOC2	soc-2 suppressor of clear homolog (C. elegans)
chr2_-_62081254	0.02	ENST00000405894.3	FAM161A	family with sequence similarity 161, member A
chr11_-_62572901	0.02	ENST00000439713.2 ENST00000531131.1 ENST00000530875.1 ENST00000531709.2 ENST00000294172.2	NXF1	nuclear RNA export factor 1
chr14_+_56078695	0.01	ENST00000416613.1	KTN1	kinectin 1 (kinesin receptor)
chr6_+_134758827	0.01	ENST00000431422.1	LINC01010	long intergenic non-protein coding RNA 1010
chr1_-_86861936	0.01	ENST00000394733.2 ENST00000359242.3 ENST00000294678.2 ENST00000479890.1 ENST00000317336.7 ENST00000370567.1 ENST00000394731.1 ENST00000478286.2 ENST00000370566.3	ODF2L	outer dense fiber of sperm tails 2-like
chr2_-_62081148	0.01	ENST00000404929.1	FAM161A	family with sequence similarity 161, member A
chr14_-_23623577	0.00	ENST00000422941.2 ENST00000453702.1	SLC7A8	solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr12_-_57113333	0.00	ENST00000550920.1	NACA	nascent polypeptide-associated complex alpha subunit
chr22_-_32334403	0.00	ENST00000543051.1	C22orf24	chromosome 22 open reading frame 24
chr12_+_51633061	0.00	ENST00000551313.1	DAZAP2	DAZ associated protein 2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	1.9	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	2.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	3.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	2.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.0	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.5	GO:0005927	muscle tendon junction(GO:0005927)
0.2	1.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232) extrinsic component of endosome membrane(GO:0031313)
0.2	2.1	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.7	GO:0045160	myosin I complex(GO:0045160)
0.2	2.5	GO:0030478	actin cap(GO:0030478)
0.2	0.9	GO:1990584	cardiac Troponin complex(GO:1990584)
0.1	0.4	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	1.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	0.8	GO:0034464	BBSome(GO:0034464)
0.1	0.9	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	1.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	2.1	GO:0005685	U1 snRNP(GO:0005685)
0.1	4.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	1.0	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.2	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	0.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.5	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0042643	actomyosin, actin portion(GO:0042643)
0.0	0.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	1.5	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.3	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	0.1	GO:0002079	inner acrosomal membrane(GO:0002079)
0.0	0.8	GO:0005581	collagen trimer(GO:0005581)
0.0	0.6	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.3	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.1	GO:0032807	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:0004781	adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3	2.1	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.3	2.6	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.3	GO:0004882	androgen receptor activity(GO:0004882)
0.2	1.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	1.4	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.4	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.1	1.9	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	3.5	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.6	GO:0001132	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1	1.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	1.2	GO:0001083	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.5	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	1.4	GO:0043295	glutathione binding(GO:0043295)
0.1	0.2	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1	1.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	1.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	1.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.2	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.1	0.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	1.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.9	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.4	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.7	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	2.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	2.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	4.6	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.5	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	1.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0004819	glutamine-tRNA ligase activity(GO:0004819)
0.0	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.3	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.3	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0031014	troponin T binding(GO:0031014)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.8	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.3	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.0	GO:0008431	vitamin E binding(GO:0008431)
0.0	2.1	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	3.5	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	1.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.8	2.5	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6	2.5	GO:0000103	sulfate assimilation(GO:0000103)
0.5	2.1	GO:0021564	vagus nerve development(GO:0021564)
0.4	1.3	GO:0060599	lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.4	1.2	GO:1900138	negative regulation of phospholipase A2 activity(GO:1900138)
0.4	4.7	GO:0035372	protein localization to microtubule(GO:0035372)
0.3	1.4	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.3	0.8	GO:1901873	regulation of post-translational protein modification(GO:1901873)
0.3	1.3	GO:0097338	response to clozapine(GO:0097338)
0.2	0.9	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.2	0.5	GO:0001554	luteolysis(GO:0001554)
0.1	0.7	GO:0035936	testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1	0.9	GO:0051414	response to cortisol(GO:0051414)
0.1	0.7	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.6	GO:0036369	transcription factor catabolic process(GO:0036369)
0.1	0.3	GO:0045925	positive regulation of female receptivity(GO:0045925)
0.1	2.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.4	GO:1903935	response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.1	1.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	0.3	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1	0.2	GO:0097359	UDP-glucosylation(GO:0097359)
0.1	1.4	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.1	0.2	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1	0.8	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.3	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	0.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	1.6	GO:0010842	retina layer formation(GO:0010842)
0.1	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.1	0.6	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.1	0.5	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	1.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	2.0	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.3	GO:0009597	detection of virus(GO:0009597)
0.0	0.8	GO:0009650	UV protection(GO:0009650)
0.0	0.3	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0016333	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.2	GO:0015824	proline transport(GO:0015824)
0.0	1.1	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.2	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.9	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.1	GO:0006425	glutaminyl-tRNA aminoacylation(GO:0006425)
0.0	0.5	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0051102	DNA ligation involved in DNA recombination(GO:0051102)
0.0	0.4	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.4	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.5	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.5	GO:0007628	adult walking behavior(GO:0007628)
0.0	0.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.9	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.9	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	1.1	GO:0006687	glycosphingolipid metabolic process(GO:0006687)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.8	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)