ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
HMX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000215612.5	HMX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMX1	hg19_v2_chr4_-_8873531_8873543	-0.57	2.2e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr5_-_81046841	4.44	ENST00000509013.2 ENST00000505980.1 ENST00000509053.1	SSBP2	single-stranded DNA binding protein 2
chr5_-_81046922	4.28	ENST00000514493.1 ENST00000320672.4	SSBP2	single-stranded DNA binding protein 2
chr5_-_81046904	3.94	ENST00000515395.1	SSBP2	single-stranded DNA binding protein 2
chr14_+_31343747	3.67	ENST00000216361.4 ENST00000396618.3 ENST00000475087.1	COCH	cochlin
chr14_+_31343951	3.65	ENST00000556908.1 ENST00000555881.1 ENST00000460581.2	COCH	cochlin
chr7_+_128470431	3.59	ENST00000325888.8 ENST00000346177.6	FLNC	filamin C, gamma
chrX_+_37545012	3.13	ENST00000378616.3	XK	X-linked Kx blood group (McLeod syndrome)
chr7_+_50344289	3.06	ENST00000413698.1 ENST00000359197.5 ENST00000331340.3 ENST00000357364.4 ENST00000343574.5 ENST00000349824.4 ENST00000346667.4 ENST00000440768.2	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr7_-_150675372	2.93	ENST00000262186.5	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr17_+_40440481	2.47	ENST00000590726.2 ENST00000452307.2 ENST00000444283.1 ENST00000588868.1	STAT5A	signal transducer and activator of transcription 5A
chr11_-_417388	2.38	ENST00000332725.3	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr11_-_417308	2.25	ENST00000397632.3 ENST00000382520.2	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr15_-_58306295	2.10	ENST00000559517.1	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr3_+_151986709	2.05	ENST00000495875.2 ENST00000493459.1 ENST00000324210.5 ENST00000459747.1	MBNL1	muscleblind-like splicing regulator 1
chr17_-_62097927	2.03	ENST00000578313.1 ENST00000584084.1 ENST00000579788.1 ENST00000579687.1 ENST00000578379.1 ENST00000578892.1 ENST00000412356.1 ENST00000418105.1	ICAM2	intercellular adhesion molecule 2
chr5_-_37371163	1.93	ENST00000513532.1	NUP155	nucleoporin 155kDa
chr16_+_85645007	1.87	ENST00000405402.2	GSE1	Gse1 coiled-coil protein
chr17_+_79989500	1.86	ENST00000306897.4	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_+_79989937	1.85	ENST00000580965.1	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr13_+_42031679	1.82	ENST00000379359.3	RGCC	regulator of cell cycle
chr17_-_62097904	1.81	ENST00000583366.1	ICAM2	intercellular adhesion molecule 2
chr5_-_37371278	1.71	ENST00000231498.3	NUP155	nucleoporin 155kDa
chr1_-_28241024	1.66	ENST00000313433.7 ENST00000444045.1	RPA2	replication protein A2, 32kDa
chr8_+_145438870	1.66	ENST00000527931.1	FAM203B	family with sequence similarity 203, member B
chr17_+_79990058	1.63	ENST00000584341.1	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr4_-_144940477	1.60	ENST00000513128.1 ENST00000429670.2 ENST00000502664.1	GYPB	glycophorin B (MNS blood group)
chr16_+_88872176	1.58	ENST00000569140.1	CDT1	chromatin licensing and DNA replication factor 1
chr1_+_15986364	1.58	ENST00000345034.1	RSC1A1	regulatory solute carrier protein, family 1, member 1
chr1_-_51425902	1.46	ENST00000396153.2	FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_54405773	1.46	ENST00000371376.1	HSPB11	heat shock protein family B (small), member 11
chr3_+_69788576	1.42	ENST00000352241.4 ENST00000448226.2	MITF	microphthalmia-associated transcription factor
chr11_+_59522900	1.41	ENST00000529177.1	STX3	syntaxin 3
chr3_+_20081515	1.38	ENST00000263754.4	KAT2B	K(lysine) acetyltransferase 2B
chr1_-_26232951	1.34	ENST00000426559.2 ENST00000455785.2	STMN1	stathmin 1
chr4_-_144826682	1.24	ENST00000358615.4 ENST00000437468.2	GYPE	glycophorin E (MNS blood group)
chr17_-_41132010	1.22	ENST00000409103.1 ENST00000360221.4	PTGES3L-AARSD1	PTGES3L-AARSD1 readthrough
chr6_+_33043703	1.15	ENST00000418931.2 ENST00000535465.1	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr6_+_163835669	1.14	ENST00000453779.2 ENST00000275262.7 ENST00000392127.2 ENST00000361752.3	QKI	QKI, KH domain containing, RNA binding
chr1_-_51425772	1.06	ENST00000371778.4	FAF1	Fas (TNFRSF6) associated factor 1
chr3_-_13461807	1.05	ENST00000254508.5	NUP210	nucleoporin 210kDa
chr9_-_74525658	1.04	ENST00000333421.6	ABHD17B	abhydrolase domain containing 17B
chr20_+_30639991	1.04	ENST00000534862.1 ENST00000538448.1 ENST00000375862.2	HCK	hemopoietic cell kinase
chr11_+_1411503	1.04	ENST00000526678.1	BRSK2	BR serine/threonine kinase 2
chr11_+_59522837	1.04	ENST00000437946.2	STX3	syntaxin 3
chr17_-_47755436	1.03	ENST00000505581.1 ENST00000514121.1 ENST00000393328.2 ENST00000509079.1 ENST00000393331.3 ENST00000347630.2 ENST00000504102.1	SPOP	speckle-type POZ protein
chr2_+_46769798	1.03	ENST00000238738.4	RHOQ	ras homolog family member Q
chr11_+_105948216	1.02	ENST00000278618.4	AASDHPPT	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr6_-_32157947	0.99	ENST00000375050.4	PBX2	pre-B-cell leukemia homeobox 2
chr20_+_30640004	0.98	ENST00000520553.1 ENST00000518730.1 ENST00000375852.2	HCK	hemopoietic cell kinase
chr5_+_10353780	0.97	ENST00000449913.2 ENST00000503788.1 ENST00000274140.5	MARCH6	membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
chr16_+_85646763	0.95	ENST00000411612.1 ENST00000253458.7	GSE1	Gse1 coiled-coil protein
chr1_+_150521876	0.95	ENST00000369041.5 ENST00000271643.4 ENST00000538795.1	ADAMTSL4 AL356356.1	ADAMTS-like 4 Protein LOC100996516
chr16_-_1823114	0.94	ENST00000177742.3 ENST00000397375.2	MRPS34	mitochondrial ribosomal protein S34
chr20_-_41818373	0.93	ENST00000373187.1 ENST00000356100.2 ENST00000373184.1 ENST00000373190.1	PTPRT	protein tyrosine phosphatase, receptor type, T
chr3_-_49066811	0.93	ENST00000442157.1 ENST00000326739.4	IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr1_-_25256368	0.92	ENST00000308873.6	RUNX3	runt-related transcription factor 3
chr9_-_126692386	0.92	ENST00000373624.2 ENST00000394219.3 ENST00000373620.3 ENST00000394215.2 ENST00000373618.1	DENND1A	DENN/MADD domain containing 1A
chr11_+_66624527	0.92	ENST00000393952.3	LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chrX_+_69509927	0.89	ENST00000374403.3	KIF4A	kinesin family member 4A
chr1_+_110163709	0.84	ENST00000369840.2 ENST00000527846.1	AMPD2	adenosine monophosphate deaminase 2
chr2_+_30454390	0.84	ENST00000395323.3 ENST00000406087.1 ENST00000404397.1	LBH	limb bud and heart development
chr14_-_55369525	0.83	ENST00000543643.2 ENST00000536224.2 ENST00000395514.1 ENST00000491895.2	GCH1	GTP cyclohydrolase 1
chr17_-_55038375	0.83	ENST00000240316.4	COIL	coilin
chr13_+_43148281	0.82	ENST00000239849.6 ENST00000398795.2 ENST00000544862.1	TNFSF11	tumor necrosis factor (ligand) superfamily, member 11
chr1_-_28241226	0.82	ENST00000373912.3 ENST00000373909.3	RPA2	replication protein A2, 32kDa
chr17_-_78450398	0.81	ENST00000306773.4	NPTX1	neuronal pentraxin I
chr22_-_39268308	0.80	ENST00000407418.3	CBX6	chromobox homolog 6
chr6_-_31550192	0.80	ENST00000429299.2 ENST00000446745.2	LTB	lymphotoxin beta (TNF superfamily, member 3)
chrX_-_153744507	0.80	ENST00000442929.1 ENST00000426266.1 ENST00000359889.5 ENST00000369641.3 ENST00000447601.2 ENST00000434658.2	FAM3A	family with sequence similarity 3, member A
chr4_+_86396265	0.80	ENST00000395184.1	ARHGAP24	Rho GTPase activating protein 24
chr17_-_41132410	0.80	ENST00000409446.3 ENST00000453594.1 ENST00000409399.1 ENST00000421990.2	PTGES3L PTGES3L-AARSD1	prostaglandin E synthase 3 (cytosolic)-like PTGES3L-AARSD1 readthrough
chrX_-_153744434	0.77	ENST00000369643.1 ENST00000393572.1	FAM3A	family with sequence similarity 3, member A
chr6_+_30524663	0.76	ENST00000376560.3	PRR3	proline rich 3
chr9_-_74525847	0.76	ENST00000377041.2	ABHD17B	abhydrolase domain containing 17B
chr7_-_752577	0.75	ENST00000544935.1 ENST00000430040.1 ENST00000456696.2 ENST00000406797.1	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_-_7077125	0.74	ENST00000545555.2	PHB2	prohibitin 2
chr6_+_20403997	0.74	ENST00000535432.1	E2F3	E2F transcription factor 3
chr11_-_128392085	0.73	ENST00000526145.2 ENST00000531611.1 ENST00000319397.6 ENST00000345075.4 ENST00000535549.1	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr9_-_136024721	0.73	ENST00000393160.3	RALGDS	ral guanine nucleotide dissociation stimulator
chr1_-_24194771	0.71	ENST00000374479.3	FUCA1	fucosidase, alpha-L- 1, tissue
chr19_-_14316980	0.70	ENST00000361434.3 ENST00000340736.6	LPHN1	latrophilin 1
chr19_-_13068012	0.68	ENST00000316939.1	GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr11_-_62607036	0.67	ENST00000311713.7 ENST00000278856.4	WDR74	WD repeat domain 74
chr6_-_89927151	0.67	ENST00000454853.2	GABRR1	gamma-aminobutyric acid (GABA) A receptor, rho 1
chr1_-_26232522	0.66	ENST00000399728.1	STMN1	stathmin 1
chr3_-_138553779	0.66	ENST00000461451.1	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr6_-_7911042	0.66	ENST00000379757.4	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr21_-_40685477	0.65	ENST00000342449.3	BRWD1	bromodomain and WD repeat domain containing 1
chr1_+_110163202	0.65	ENST00000531203.1 ENST00000256578.3	AMPD2	adenosine monophosphate deaminase 2
chrX_+_110924346	0.65	ENST00000371979.3 ENST00000251943.4 ENST00000486353.1 ENST00000394780.3 ENST00000495283.1	ALG13	ALG13, UDP-N-acetylglucosaminyltransferase subunit
chrX_+_131157290	0.64	ENST00000394334.2	MST4	Serine/threonine-protein kinase MST4
chr3_-_138553594	0.63	ENST00000477593.1 ENST00000483968.1	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr14_-_101034407	0.63	ENST00000443071.2 ENST00000557378.1	BEGAIN	brain-enriched guanylate kinase-associated
chr19_-_1401486	0.62	ENST00000252288.2 ENST00000447102.3	GAMT	guanidinoacetate N-methyltransferase
chr19_+_41305406	0.62	ENST00000406058.2 ENST00000593726.1	EGLN2	egl-9 family hypoxia-inducible factor 2
chr11_+_6502675	0.61	ENST00000254616.6 ENST00000530751.1	TIMM10B	translocase of inner mitochondrial membrane 10 homolog B (yeast)
chr7_-_37488834	0.61	ENST00000310758.4	ELMO1	engulfment and cell motility 1
chr21_-_42879909	0.60	ENST00000458356.1 ENST00000398585.3 ENST00000424093.1	TMPRSS2	transmembrane protease, serine 2
chr1_-_153949751	0.60	ENST00000428469.1	JTB	jumping translocation breakpoint
chrX_+_131157322	0.60	ENST00000481105.1 ENST00000354719.6 ENST00000394335.2	MST4	Serine/threonine-protein kinase MST4
chr6_-_8102279	0.59	ENST00000488226.2	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1
chr1_+_110163682	0.59	ENST00000358729.4	AMPD2	adenosine monophosphate deaminase 2
chr1_+_193091080	0.59	ENST00000367435.3	CDC73	cell division cycle 73
chr19_+_41313017	0.58	ENST00000595621.1 ENST00000595051.1	EGLN2	egl-9 family hypoxia-inducible factor 2
chr17_+_79679299	0.57	ENST00000331531.5	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr20_-_41818536	0.57	ENST00000373193.3 ENST00000373198.4 ENST00000373201.1	PTPRT	protein tyrosine phosphatase, receptor type, T
chr22_-_37640456	0.57	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_109940550	0.56	ENST00000256637.6	SORT1	sortilin 1
chr14_+_90422239	0.56	ENST00000393452.3 ENST00000554180.1 ENST00000393454.2 ENST00000553617.1 ENST00000335725.4 ENST00000357382.3 ENST00000556867.1 ENST00000553527.1	TDP1	tyrosyl-DNA phosphodiesterase 1
chr12_+_53689309	0.56	ENST00000351500.3 ENST00000550846.1 ENST00000334478.4 ENST00000549759.1	PFDN5	prefoldin subunit 5
chr1_+_95583479	0.55	ENST00000455656.1 ENST00000604534.1	TMEM56 RP11-57H12.6	transmembrane protein 56 TMEM56-RWDD3 readthrough
chr6_-_8102714	0.55	ENST00000502429.1 ENST00000429723.2 ENST00000507463.1 ENST00000379715.5	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1
chr4_+_83956312	0.55	ENST00000509317.1 ENST00000503682.1 ENST00000511653.1	COPS4	COP9 signalosome subunit 4
chr4_+_83956237	0.54	ENST00000264389.2	COPS4	COP9 signalosome subunit 4
chr1_-_115259337	0.53	ENST00000369535.4	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog
chr14_+_72399114	0.52	ENST00000553525.1 ENST00000555571.1	RGS6	regulator of G-protein signaling 6
chr22_-_37640277	0.52	ENST00000401529.3 ENST00000249071.6	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr15_+_81489213	0.51	ENST00000559383.1 ENST00000394660.2	IL16	interleukin 16
chr3_-_195270162	0.51	ENST00000438848.1 ENST00000328432.3	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2
chrX_+_135579670	0.50	ENST00000218364.4	HTATSF1	HIV-1 Tat specific factor 1
chr1_-_46598284	0.49	ENST00000423209.1 ENST00000262741.5	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr12_+_70133152	0.49	ENST00000550536.1 ENST00000362025.5	RAB3IP	RAB3A interacting protein
chr17_+_79679369	0.48	ENST00000350690.5	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr21_-_42880075	0.48	ENST00000332149.5	TMPRSS2	transmembrane protease, serine 2
chr15_+_89346699	0.48	ENST00000558207.1	ACAN	aggrecan
chr11_-_19262486	0.48	ENST00000250024.4	E2F8	E2F transcription factor 8
chr5_+_156693159	0.48	ENST00000347377.6	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr1_-_207095324	0.47	ENST00000530505.1 ENST00000367091.3 ENST00000442471.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr2_-_175462456	0.46	ENST00000409891.1 ENST00000410117.1	WIPF1	WAS/WASL interacting protein family, member 1
chr17_-_8151353	0.45	ENST00000315684.8	CTC1	CTS telomere maintenance complex component 1
chr2_-_175462934	0.45	ENST00000392546.2 ENST00000436221.1	WIPF1	WAS/WASL interacting protein family, member 1
chr22_-_29196030	0.44	ENST00000405219.3	XBP1	X-box binding protein 1
chr13_+_37574678	0.43	ENST00000389704.3	EXOSC8	exosome component 8
chr14_-_25103388	0.43	ENST00000526004.1 ENST00000415355.3	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_-_207095212	0.43	ENST00000420007.2	FAIM3	Fas apoptotic inhibitory molecule 3
chr5_+_156693091	0.43	ENST00000318218.6 ENST00000442283.2 ENST00000522463.1 ENST00000521420.1	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr11_-_67275542	0.42	ENST00000531506.1	CDK2AP2	cyclin-dependent kinase 2 associated protein 2
chr2_-_24583168	0.42	ENST00000361999.3	ITSN2	intersectin 2
chr5_+_176784837	0.42	ENST00000408923.3	RGS14	regulator of G-protein signaling 14
chr12_-_49259643	0.41	ENST00000309739.5	RND1	Rho family GTPase 1
chr3_+_39093481	0.41	ENST00000302313.5 ENST00000544962.1 ENST00000396258.3 ENST00000418020.1	WDR48	WD repeat domain 48
chr12_+_7060432	0.41	ENST00000318974.9 ENST00000456013.1	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chrX_-_153599578	0.41	ENST00000360319.4 ENST00000344736.4	FLNA	filamin A, alpha
chr17_-_79876010	0.41	ENST00000328666.6	SIRT7	sirtuin 7
chr9_+_10613163	0.40	ENST00000429581.2	RP11-87N24.2	RP11-87N24.2
chr1_-_46598371	0.40	ENST00000372006.1 ENST00000425892.1 ENST00000420542.1 ENST00000354242.4 ENST00000340332.6	PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr17_-_42298201	0.40	ENST00000527034.1	UBTF	upstream binding transcription factor, RNA polymerase I
chr4_-_151936416	0.40	ENST00000510413.1 ENST00000507224.1	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr1_+_178995021	0.40	ENST00000263733.4	FAM20B	family with sequence similarity 20, member B
chr1_+_235490659	0.39	ENST00000488594.1	GGPS1	geranylgeranyl diphosphate synthase 1
chr14_-_25103472	0.39	ENST00000216341.4 ENST00000382542.1 ENST00000382540.1	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr4_-_151936865	0.39	ENST00000535741.1	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr2_-_27545431	0.38	ENST00000233545.2	MPV17	MpV17 mitochondrial inner membrane protein
chr12_+_70132632	0.38	ENST00000378815.6 ENST00000483530.2 ENST00000325555.9	RAB3IP	RAB3A interacting protein
chrX_+_135579238	0.38	ENST00000535601.1 ENST00000448450.1 ENST00000425695.1	HTATSF1	HIV-1 Tat specific factor 1
chr8_+_120428546	0.38	ENST00000259526.3	NOV	nephroblastoma overexpressed
chr4_-_71705027	0.37	ENST00000545193.1	GRSF1	G-rich RNA sequence binding factor 1
chr1_+_160336851	0.37	ENST00000302101.5	NHLH1	nescient helix loop helix 1
chr3_-_52312636	0.37	ENST00000296490.3	WDR82	WD repeat domain 82
chr4_-_109087872	0.37	ENST00000510624.1	LEF1	lymphoid enhancer-binding factor 1
chr12_+_41831485	0.37	ENST00000539469.2 ENST00000298919.7	PDZRN4	PDZ domain containing ring finger 4
chr16_+_19535133	0.36	ENST00000396212.2 ENST00000381396.5	CCP110	centriolar coiled coil protein 110kDa
chr22_-_39268192	0.36	ENST00000216083.6	CBX6	chromobox homolog 6
chr4_-_140005443	0.36	ENST00000510408.1 ENST00000420916.2 ENST00000358635.3	ELF2	E74-like factor 2 (ets domain transcription factor)
chr17_-_8534067	0.36	ENST00000360416.3 ENST00000269243.4	MYH10	myosin, heavy chain 10, non-muscle
chr19_-_19006890	0.35	ENST00000247005.6	GDF1	growth differentiation factor 1
chr16_+_67226019	0.35	ENST00000379378.3	E2F4	E2F transcription factor 4, p107/p130-binding
chr16_+_19535235	0.34	ENST00000565376.2 ENST00000396208.2	CCP110	centriolar coiled coil protein 110kDa
chr10_-_7708918	0.34	ENST00000256861.6 ENST00000397146.2 ENST00000446830.2 ENST00000397145.2	ITIH5	inter-alpha-trypsin inhibitor heavy chain family, member 5
chr9_-_130616915	0.34	ENST00000344849.3	ENG	endoglin
chr5_+_112043186	0.33	ENST00000509732.1 ENST00000457016.1 ENST00000507379.1	APC	adenomatous polyposis coli
chr8_+_98881268	0.32	ENST00000254898.5 ENST00000524308.1 ENST00000522025.2	MATN2	matrilin 2
chr19_-_7939319	0.32	ENST00000539422.1	CTD-3193O13.9	Protein FLJ22184
chr12_-_42631529	0.32	ENST00000548917.1	YAF2	YY1 associated factor 2
chr20_+_49348081	0.32	ENST00000371610.2	PARD6B	par-6 family cell polarity regulator beta
chr4_-_140005341	0.32	ENST00000379549.2 ENST00000512627.1	ELF2	E74-like factor 2 (ets domain transcription factor)
chr11_-_78285804	0.31	ENST00000281038.5 ENST00000529571.1	NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr1_+_39456895	0.31	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1	akirin 1
chr17_-_42298331	0.31	ENST00000343638.5	UBTF	upstream binding transcription factor, RNA polymerase I
chr18_-_56940611	0.31	ENST00000256852.7 ENST00000334889.3	RAX	retina and anterior neural fold homeobox
chr17_+_77751931	0.31	ENST00000310942.4 ENST00000269399.5	CBX2	chromobox homolog 2
chr19_-_55686399	0.31	ENST00000587067.1	SYT5	synaptotagmin V
chr19_-_19006920	0.30	ENST00000429504.2 ENST00000427170.2	CERS1	ceramide synthase 1
chr19_+_41305085	0.30	ENST00000303961.4	EGLN2	egl-9 family hypoxia-inducible factor 2
chr19_-_46285646	0.30	ENST00000458663.2	DMPK	dystrophia myotonica-protein kinase
chr7_+_155250824	0.30	ENST00000297375.4	EN2	engrailed homeobox 2
chr11_-_19223523	0.29	ENST00000265968.3	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr17_-_7165662	0.29	ENST00000571881.2 ENST00000360325.7	CLDN7	claudin 7
chr2_-_27545921	0.29	ENST00000402310.1 ENST00000405983.1 ENST00000403262.2 ENST00000428910.1 ENST00000402722.1 ENST00000399052.4 ENST00000380044.1 ENST00000405076.1	MPV17	MpV17 mitochondrial inner membrane protein
chr15_+_33010175	0.28	ENST00000300177.4 ENST00000560677.1 ENST00000560830.1	GREM1	gremlin 1, DAN family BMP antagonist
chr8_-_17270809	0.27	ENST00000180173.5 ENST00000521857.1	MTMR7	myotubularin related protein 7
chr19_-_10341948	0.27	ENST00000590320.1 ENST00000592342.1 ENST00000588952.1	S1PR2 DNMT1	sphingosine-1-phosphate receptor 2 DNA (cytosine-5-)-methyltransferase 1
chr17_+_38465441	0.27	ENST00000577646.1 ENST00000254066.5	RARA	retinoic acid receptor, alpha
chr11_+_129245796	0.27	ENST00000281437.4	BARX2	BARX homeobox 2
chr12_+_125478241	0.27	ENST00000341446.8	BRI3BP	BRI3 binding protein
chr6_-_10882174	0.26	ENST00000379491.4	GCM2	glial cells missing homolog 2 (Drosophila)
chr12_+_57482665	0.26	ENST00000300131.3	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_35783047	0.26	ENST00000595791.1 ENST00000597035.1 ENST00000537831.2	MAG	myelin associated glycoprotein
chr3_-_67705006	0.25	ENST00000492795.1 ENST00000493112.1 ENST00000307227.5	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit
chr1_+_226411319	0.24	ENST00000542034.1 ENST00000366810.5	MIXL1	Mix paired-like homeobox

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	3.1	GO:0031133	regulation of axon diameter(GO:0031133)
1.0	2.9	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.9	3.6	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.7	2.0	GO:0002522	leukocyte migration involved in immune response(GO:0002522)
0.7	4.6	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.6	2.5	GO:0000255	allantoin metabolic process(GO:0000255)
0.6	1.8	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.5	1.6	GO:1902595	regulation of DNA replication origin binding(GO:1902595)
0.5	1.6	GO:0061760	antifungal innate immune response(GO:0061760)
0.5	1.4	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.4	5.3	GO:0021894	cerebral cortex GABAergic interneuron development(GO:0021894)
0.4	2.0	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4	1.1	GO:0015709	thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.3	2.4	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3	0.8	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.3	0.8	GO:0100009	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.3	1.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.3	1.3	GO:2000035	regulation of stem cell division(GO:2000035)
0.2	2.1	GO:0035799	ureter maturation(GO:0035799)
0.2	2.0	GO:0032264	IMP salvage(GO:0032264)
0.2	0.6	GO:0035470	positive regulation of vascular wound healing(GO:0035470) regulation of lactation(GO:1903487)
0.2	0.6	GO:0021678	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.2	0.6	GO:0001300	chronological cell aging(GO:0001300)
0.2	1.5	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2	0.7	GO:0032053	ciliary basal body organization(GO:0032053)
0.2	0.9	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	0.9	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	2.5	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.7	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.7	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.1	0.4	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.1	1.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.1	0.4	GO:0033386	geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1	0.4	GO:1990523	bone regeneration(GO:1990523)
0.1	0.1	GO:0048073	regulation of eye pigmentation(GO:0048073)
0.1	0.5	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	2.5	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.8	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	1.5	GO:0070986	left/right axis specification(GO:0070986)
0.1	0.4	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1	1.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	1.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.1	0.4	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	0.8	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1	0.8	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.1	0.5	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.1	1.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1	0.3	GO:1900158	negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1	0.7	GO:1904996	PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1	0.4	GO:0048539	bone marrow development(GO:0048539)
0.1	0.7	GO:0016139	glycoside catabolic process(GO:0016139)
0.1	0.8	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.2	GO:0071409	cellular response to cycloheximide(GO:0071409)
0.1	0.2	GO:0051885	positive regulation of anagen(GO:0051885)
0.1	0.6	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.5	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	0.3	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.7	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.1	0.3	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	1.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.4	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.0	GO:1904152	regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.1	1.1	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.3	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	3.5	GO:0048747	muscle fiber development(GO:0048747)
0.1	0.6	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.1	0.6	GO:0000012	single strand break repair(GO:0000012)
0.1	0.2	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1	0.5	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.1	0.9	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	0.7	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.1	0.2	GO:1904383	response to sodium phosphate(GO:1904383)
0.1	1.0	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1	0.2	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.3	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.7	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.6	GO:0001711	endodermal cell fate commitment(GO:0001711)
0.0	0.8	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	7.3	GO:0007605	sensory perception of sound(GO:0007605)
0.0	0.3	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) parathyroid gland development(GO:0060017) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.0	GO:0055073	cadmium ion homeostasis(GO:0055073)
0.0	1.0	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.6	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.3	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.2	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0	0.3	GO:1902949	positive regulation of tau-protein kinase activity(GO:1902949)
0.0	0.2	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.4	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.9	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.3	GO:1990403	embryonic brain development(GO:1990403)
0.0	1.4	GO:0030318	melanocyte differentiation(GO:0030318)
0.0	0.4	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.0	0.7	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.0	0.2	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.2	GO:0060536	growth plate cartilage chondrocyte differentiation(GO:0003418) cartilage morphogenesis(GO:0060536)
0.0	1.1	GO:0043304	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0	4.4	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.5	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	1.1	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.7	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.9	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.3	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.3	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	2.9	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.7	GO:0007265	Ras protein signal transduction(GO:0007265)
0.0	0.1	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.0	0.1	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.2	GO:0030220	platelet formation(GO:0030220)
0.0	0.1	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.0	2.0	GO:0030326	embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0	0.2	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.5	GO:1903861	regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	1.2	GO:0032729	positive regulation of interferon-gamma production(GO:0032729)
0.0	0.3	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.3	GO:0035909	aorta morphogenesis(GO:0035909)
0.0	0.2	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.3	GO:0001502	cartilage condensation(GO:0001502)
0.0	0.9	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.2	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.0	0.5	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.4	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.7	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0031929	TOR signaling(GO:0031929) regulation of TOR signaling(GO:0032006)
0.0	1.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0043303	mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	3.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	3.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	4.7	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	3.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	1.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.0	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	2.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.9	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	1.6	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	1.5	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	3.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	7.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	4.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	1.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.8	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME KINESINS	Genes involved in Kinesins
0.0	1.1	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.9	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.7	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.7	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.8	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.1	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.6	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	3.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	4.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.7	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	2.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	1.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	2.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.8	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	7.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.0	PID AURORA B PATHWAY	Aurora B signaling
0.0	2.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	2.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	1.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.3	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.6	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.5	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.5	2.9	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.4	1.1	GO:0015131	thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.3	1.0	GO:0032427	GBD domain binding(GO:0032427)
0.3	1.5	GO:0070097	delta-catenin binding(GO:0070097)
0.3	1.4	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3	2.9	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.2	0.9	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.2	2.4	GO:0050542	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.2	2.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2	1.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2	2.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	1.5	GO:0019826	oxygen sensor activity(GO:0019826)
0.1	0.6	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1	0.8	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.4	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.1	3.5	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.1	0.6	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	3.2	GO:0030506	ankyrin binding(GO:0030506)
0.1	12.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	0.4	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.7	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1	1.0	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.6	GO:0005534	galactose binding(GO:0005534)
0.1	2.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.7	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.2	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	5.4	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	0.6	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.9	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	1.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	1.0	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	1.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	3.9	GO:0005518	collagen binding(GO:0005518)
0.0	0.3	GO:0016015	morphogen activity(GO:0016015)
0.0	0.4	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.0	1.6	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	1.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.7	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.2	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	1.2	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.3	GO:0031433	telethonin binding(GO:0031433)
0.0	0.9	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	1.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.6	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.4	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.3	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	0.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	1.4	GO:0030331	estrogen receptor binding(GO:0030331)
0.0	0.2	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	1.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.5	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	1.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.0	1.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.3	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0004657	proline dehydrogenase activity(GO:0004657)
0.0	0.7	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.3	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.9	GO:0070888	E-box binding(GO:0070888)
0.0	2.2	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	2.1	GO:0005178	integrin binding(GO:0005178)
0.0	1.2	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.4	GO:0017091	AU-rich element binding(GO:0017091)
0.0	2.1	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.0	1.1	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.3	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	3.6	GO:0044611	nuclear pore inner ring(GO:0044611)
0.6	2.4	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.6	2.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.3	0.5	GO:0070821	tertiary granule membrane(GO:0070821)
0.2	3.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.2	0.6	GO:0072563	endothelial microparticle(GO:0072563)
0.2	2.5	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	3.8	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	2.5	GO:0005662	DNA replication factor A complex(GO:0005662)
0.2	0.6	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2	1.0	GO:0000835	ER ubiquitin ligase complex(GO:0000835)
0.2	1.4	GO:0000125	PCAF complex(GO:0000125)
0.1	0.6	GO:0097513	myosin II filament(GO:0097513)
0.1	0.4	GO:0031523	Myb complex(GO:0031523)
0.1	5.3	GO:0031941	filamentous actin(GO:0031941)
0.1	0.3	GO:1990015	mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1	0.9	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:1990130	Iml1 complex(GO:1990130)
0.1	2.0	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.6	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.6	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	3.6	GO:0043034	costamere(GO:0043034)
0.1	0.3	GO:1990769	proximal neuron projection(GO:1990769)
0.1	0.6	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.2	GO:0097441	basilar dendrite(GO:0097441)
0.1	1.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.1	1.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	1.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	4.3	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.9	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.2	GO:0071817	MMXD complex(GO:0071817)
0.0	0.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.4	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.4	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.4	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	2.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	1.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.4	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	1.5	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.7	GO:1902711	GABA-A receptor complex(GO:1902711)
0.0	0.9	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.6	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	1.6	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	5.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.8	GO:0030133	transport vesicle(GO:0030133)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.1	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.0	0.8	GO:0015030	Cajal body(GO:0015030)
0.0	1.0	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.6	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)