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ENCODE cell lines, expression (Ernst 2011)

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Results for HMX2

Z-value: 0.84

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Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 HMX2

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_95241951 6.69 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
 MYOF
 myoferlin
chr2_-_151344172 4.38 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
 RND3
 Rho family GTPase 3
chr10_-_95242044 3.42 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
 MYOF
 myoferlin
chr1_+_99127225 2.61 ENST00000370189.5
ENST00000529992.1
 SNX7
 sorting nexin 7
chr14_+_55595762 2.05 ENST00000254301.9
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr10_-_126849588 2.05 ENST00000411419.2
 CTBP2
 C-terminal binding protein 2
chr7_-_87856303 1.87 ENST00000394641.3
 SRI
 sorcin
chr11_+_5710919 1.86 ENST00000379965.3
ENST00000425490.1
 TRIM22
 tripartite motif containing 22
chr7_-_87856280 1.76 ENST00000490437.1
ENST00000431660.1
 SRI
 sorcin
chr6_+_12290586 1.51 ENST00000379375.5
 EDN1
 endothelin 1
chr14_+_55595960 1.46 ENST00000554715.1
 LGALS3
 lectin, galactoside-binding, soluble, 3
chr2_-_190044480 1.46 ENST00000374866.3
 COL5A2
 collagen, type V, alpha 2
chr1_-_110933611 1.45 ENST00000472422.2
ENST00000437429.2
 SLC16A4
 solute carrier family 16, member 4
chr6_+_151561085 1.45 ENST00000402676.2
 AKAP12
 A kinase (PRKA) anchor protein 12
chr1_+_186798073 1.40 ENST00000367466.3
ENST00000442353.2
 PLA2G4A
 phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr13_-_38172863 1.28 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chr2_-_169104651 1.14 ENST00000355999.4
 STK39
 serine threonine kinase 39
chr4_+_90823130 1.04 ENST00000508372.1
 MMRN1
 multimerin 1
chr6_+_148663729 1.01 ENST00000367467.3
 SASH1
 SAM and SH3 domain containing 1
chr8_-_13134045 0.98 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr2_-_160654745 0.91 ENST00000259053.4
ENST00000429078.2
 CD302
 CD302 molecule
chr1_-_110933663 0.91 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
 SLC16A4
 solute carrier family 16, member 4
chr4_-_90759440 0.90 ENST00000336904.3
 SNCA
 synuclein, alpha (non A4 component of amyloid precursor)
chr6_+_114178512 0.90 ENST00000368635.4
 MARCKS
 myristoylated alanine-rich protein kinase C substrate
chr5_-_146781153 0.80 ENST00000520473.1
 DPYSL3
 dihydropyrimidinase-like 3
chr17_-_46671323 0.77 ENST00000239151.5
 HOXB5
 homeobox B5
chr12_+_104680659 0.75 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
 TXNRD1
 thioredoxin reductase 1
chr5_+_119867159 0.75 ENST00000505123.1
 PRR16
 proline rich 16
chr3_+_122785895 0.74 ENST00000316218.7
 PDIA5
 protein disulfide isomerase family A, member 5
chr5_+_140868717 0.73 ENST00000252087.1
 PCDHGC5
 protocadherin gamma subfamily C, 5
chr1_+_144151520 0.70 ENST00000369372.4
 NBPF8
 neuroblastoma breakpoint family, member 8
chr3_-_79816965 0.64 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_-_205290865 0.63 ENST00000367157.3
 NUAK2
 NUAK family, SNF1-like kinase, 2
chr6_-_46293378 0.61 ENST00000330430.6
 RCAN2
 regulator of calcineurin 2
chr8_+_32579341 0.52 ENST00000519240.1
ENST00000539990.1
 NRG1
 neuregulin 1
chr2_-_20251744 0.50 ENST00000175091.4
 LAPTM4A
 lysosomal protein transmembrane 4 alpha
chr10_-_101945771 0.49 ENST00000370408.2
ENST00000407654.3
 ERLIN1
 ER lipid raft associated 1
chr19_+_40877583 0.49 ENST00000596470.1
 PLD3
 phospholipase D family, member 3
chr2_+_24272543 0.49 ENST00000380991.4
 FKBP1B
 FK506 binding protein 1B, 12.6 kDa
chr2_+_152214098 0.49 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr2_-_111334678 0.45 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
 RGPD6
 RANBP2-like and GRIP domain containing 6
chr4_+_166248775 0.44 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
 MSMO1
 methylsterol monooxygenase 1
chr2_-_152590982 0.44 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
 NEB
 nebulin
chr1_-_217804377 0.43 ENST00000366935.3
ENST00000366934.3
 GPATCH2
 G patch domain containing 2
chr13_+_21714711 0.42 ENST00000607003.1
ENST00000492245.1
 SAP18
 Sin3A-associated protein, 18kDa
chr11_+_60681346 0.40 ENST00000227525.3
 TMEM109
 transmembrane protein 109
chr3_-_187009646 0.40 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
 MASP1
 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr11_-_327537 0.40 ENST00000602735.1
 IFITM3
 interferon induced transmembrane protein 3
chr17_+_1936687 0.39 ENST00000570477.1
 DPH1
 diphthamide biosynthesis 1
chr4_+_83956237 0.38 ENST00000264389.2
 COPS4
 COP9 signalosome subunit 4
chr1_+_209878182 0.34 ENST00000367027.3
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr18_+_76829385 0.34 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
 ATP9B
 ATPase, class II, type 9B
chr4_+_83956312 0.32 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
 COPS4
 COP9 signalosome subunit 4
chr1_-_21377447 0.32 ENST00000374937.3
ENST00000264211.8
 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
chr5_+_140227048 0.32 ENST00000532602.1
 PCDHA9
 protocadherin alpha 9
chr10_-_121296045 0.31 ENST00000392865.1
 RGS10
 regulator of G-protein signaling 10
chr2_-_55237484 0.31 ENST00000394609.2
 RTN4
 reticulon 4
chr12_+_133614119 0.30 ENST00000327668.7
 ZNF84
 zinc finger protein 84
chr7_+_5920429 0.28 ENST00000242104.5
 OCM
 oncomodulin
chr8_+_31496809 0.28 ENST00000518104.1
ENST00000519301.1
 NRG1
 neuregulin 1
chr22_+_51176624 0.28 ENST00000216139.5
ENST00000529621.1
 ACR
 acrosin
chr3_-_46249878 0.27 ENST00000296140.3
 CCR1
 chemokine (C-C motif) receptor 1
chr13_-_103426112 0.27 ENST00000376032.4
ENST00000376029.3
 TEX30
 testis expressed 30
chr3_-_114343039 0.26 ENST00000481632.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr9_+_27109133 0.26 ENST00000519097.1
ENST00000380036.4
 TEK
 TEK tyrosine kinase, endothelial
chr4_-_48782259 0.25 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
 FRYL
 FRY-like
chr1_-_21377383 0.25 ENST00000374935.3
 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
chr19_+_41281416 0.25 ENST00000597140.1
 MIA
 melanoma inhibitory activity
chr19_+_18668572 0.24 ENST00000540691.1
ENST00000539106.1
ENST00000222307.4
 KXD1
 KxDL motif containing 1
chr13_-_103426081 0.23 ENST00000376022.1
ENST00000376021.4
 TEX30
 testis expressed 30
chr7_+_141695633 0.23 ENST00000549489.2
 MGAM
 maltase-glucoamylase (alpha-glucosidase)
chr15_-_55700457 0.23 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr10_-_49813090 0.22 ENST00000249601.4
 ARHGAP22
 Rho GTPase activating protein 22
chr3_+_111697843 0.22 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
 ABHD10
 abhydrolase domain containing 10
chr1_+_115397424 0.22 ENST00000369522.3
ENST00000455987.1
 SYCP1
 synaptonemal complex protein 1
chr19_+_18668672 0.21 ENST00000601630.1
ENST00000599000.1
ENST00000595073.1
ENST00000596785.1
 KXD1
 KxDL motif containing 1
chr2_+_109237717 0.21 ENST00000409441.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr4_+_83821835 0.20 ENST00000302236.5
 THAP9
 THAP domain containing 9
chr1_-_202858227 0.20 ENST00000367262.3
 RABIF
 RAB interacting factor
chr7_+_141695671 0.20 ENST00000497673.1
ENST00000475668.2
 MGAM
 maltase-glucoamylase (alpha-glucosidase)
chr5_+_167913450 0.20 ENST00000231572.3
ENST00000538719.1
 RARS
 arginyl-tRNA synthetase
chr2_-_145277569 0.19 ENST00000303660.4
 ZEB2
 zinc finger E-box binding homeobox 2
chr17_+_45973516 0.19 ENST00000376741.4
 SP2
 Sp2 transcription factor
chr4_-_122854612 0.19 ENST00000264811.5
 TRPC3
 transient receptor potential cation channel, subfamily C, member 3
chr17_+_8191815 0.18 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
 RANGRF
 RAN guanine nucleotide release factor
chr4_-_159080806 0.18 ENST00000590648.1
 FAM198B
 family with sequence similarity 198, member B
chr19_-_51340469 0.18 ENST00000326856.4
 KLK15
 kallikrein-related peptidase 15
chr1_-_213189168 0.17 ENST00000366962.3
ENST00000360506.2
 ANGEL2
 angel homolog 2 (Drosophila)
chr1_-_67266939 0.16 ENST00000304526.2
 INSL5
 insulin-like 5
chr12_+_26164645 0.16 ENST00000542004.1
 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_-_108836977 0.15 ENST00000232603.5
 MORC1
 MORC family CW-type zinc finger 1
chr3_-_52713729 0.15 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
 PBRM1
 polybromo 1
chr6_-_106773491 0.15 ENST00000360666.4
 ATG5
 autophagy related 5
chr3_+_173116225 0.15 ENST00000457714.1
 NLGN1
 neuroligin 1
chr6_+_25754927 0.14 ENST00000377905.4
ENST00000439485.2
 SLC17A4
 solute carrier family 17, member 4
chr18_+_42260861 0.14 ENST00000282030.5
 SETBP1
 SET binding protein 1
chr13_+_27998681 0.14 ENST00000381140.4
 GTF3A
 general transcription factor IIIA
chr15_-_55700522 0.13 ENST00000564092.1
ENST00000310958.6
 CCPG1
 cell cycle progression 1
chr4_-_70518941 0.12 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
 UGT2A1
UGT2A1
 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr7_+_77325738 0.12 ENST00000334955.8
 RSBN1L
 round spermatid basic protein 1-like
chr2_-_224467093 0.11 ENST00000305409.2
 SCG2
 secretogranin II
chr4_+_76649797 0.10 ENST00000538159.1
ENST00000514213.2
 USO1
 USO1 vesicle transport factor
chr13_+_21714913 0.10 ENST00000450573.1
ENST00000467636.1
 SAP18
 Sin3A-associated protein, 18kDa
chr11_+_93517393 0.09 ENST00000251871.3
ENST00000530819.1
 MED17
 mediator complex subunit 17
chrX_+_119737806 0.09 ENST00000371317.5
 MCTS1
 malignant T cell amplified sequence 1
chrX_+_1710484 0.09 ENST00000313871.3
ENST00000381261.3
 AKAP17A
 A kinase (PRKA) anchor protein 17A
chr5_+_156607829 0.09 ENST00000422843.3
 ITK
 IL2-inducible T-cell kinase
chr12_-_123450986 0.09 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
 ABCB9
 ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr11_-_104893863 0.08 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
 CASP5
 caspase 5, apoptosis-related cysteine peptidase
chr5_-_142814241 0.08 ENST00000504572.1
 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr19_+_9361606 0.08 ENST00000456448.1
 OR7E24
 olfactory receptor, family 7, subfamily E, member 24
chr16_-_21663919 0.07 ENST00000569602.1
 IGSF6
 immunoglobulin superfamily, member 6
chr22_-_39268308 0.07 ENST00000407418.3
 CBX6
 chromobox homolog 6
chr2_+_27255806 0.06 ENST00000238788.9
ENST00000404032.3
 TMEM214
 transmembrane protein 214
chr2_+_1417228 0.06 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
 TPO
 thyroid peroxidase
chr9_-_95055956 0.06 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
 IARS
 isoleucyl-tRNA synthetase
chr19_+_54641444 0.06 ENST00000221232.5
ENST00000358389.3
 CNOT3
 CCR4-NOT transcription complex, subunit 3
chr2_+_216974020 0.06 ENST00000392132.2
ENST00000417391.1
 XRCC5
 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr3_-_194119995 0.06 ENST00000323007.3
 GP5
 glycoprotein V (platelet)
chr3_-_187009798 0.06 ENST00000337774.5
 MASP1
 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
chr20_+_33104199 0.06 ENST00000357156.2
ENST00000417166.2
ENST00000300469.9
ENST00000374846.3
 DYNLRB1
 dynein, light chain, roadblock-type 1
chr2_+_106468204 0.04 ENST00000425756.1
ENST00000393349.2
 NCK2
 NCK adaptor protein 2
chr12_-_10151773 0.04 ENST00000298527.6
ENST00000348658.4
 CLEC1B
 C-type lectin domain family 1, member B
chr5_+_95066823 0.04 ENST00000506817.1
ENST00000379982.3
 RHOBTB3
 Rho-related BTB domain containing 3
chr19_+_58144529 0.03 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
 ZNF211
 zinc finger protein 211
chr20_+_48429356 0.03 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
 SLC9A8
 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr20_+_3776371 0.03 ENST00000245960.5
 CDC25B
 cell division cycle 25B
chr1_+_196946664 0.03 ENST00000367414.5
 CFHR5
 complement factor H-related 5
chr5_-_22853429 0.02 ENST00000504376.2
 CDH12
 cadherin 12, type 2 (N-cadherin 2)
chr17_-_73663245 0.02 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
 RECQL5
 RecQ protein-like 5
chrY_+_20137667 0.02 ENST00000250838.4
ENST00000426790.1
 CDY2A
 chromodomain protein, Y-linked, 2A
chr22_+_39795746 0.02 ENST00000216160.6
ENST00000331454.3
 TAB1
 TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr1_+_196946680 0.02 ENST00000256785.4
 CFHR5
 complement factor H-related 5
chr3_-_121379739 0.01 ENST00000428394.2
ENST00000314583.3
 HCLS1
 hematopoietic cell-specific Lyn substrate 1
chr11_-_64684672 0.01 ENST00000377264.3
ENST00000421419.2
 ATG2A
 autophagy related 2A
chr4_-_100212132 0.01 ENST00000209668.2
 ADH1A
 alcohol dehydrogenase 1A (class I), alpha polypeptide
chrY_-_19992098 0.01 ENST00000544303.1
ENST00000382867.3
 CDY2B
 chromodomain protein, Y-linked, 2B
chr7_-_14880892 0.01 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
 DGKB
 diacylglycerol kinase, beta 90kDa
chr11_+_122753391 0.00 ENST00000307257.6
ENST00000227349.2
 C11orf63
 chromosome 11 open reading frame 63
chr9_+_27109392 0.00 ENST00000406359.4
 TEK
 TEK tyrosine kinase, endothelial

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0019863 IgE binding(GO:0019863)
0.3 1.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 2.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.7 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.2 0.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0016160 amylase activity(GO:0016160) maltose alpha-glucosidase activity(GO:0032450)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 3.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0004040 amidase activity(GO:0004040) fucose binding(GO:0042806)
0.1 0.8 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 2.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 10.8 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 4.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0044326 dendritic spine neck(GO:0044326)
0.5 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 2.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 10.7 GO:0005901 caveola(GO:0005901)
0.1 1.1 GO:0043073 germ cell nucleus(GO:0043073)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.0 1.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.2 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 3.4 GO:0019898 extrinsic component of membrane(GO:0019898)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.8 10.1 GO:0001778 plasma membrane repair(GO:0001778)
0.5 3.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.5 1.5 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 1.3 GO:1990523 bone regeneration(GO:1990523)
0.4 1.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4 1.5 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.4 1.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 2.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.6 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 0.9 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.2 0.2 GO:0060259 positive regulation of behavior(GO:0048520) regulation of feeding behavior(GO:0060259) positive regulation of feeding behavior(GO:2000253)
0.1 0.8 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.5 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.4 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 1.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0098923 NMDA glutamate receptor clustering(GO:0097114) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 1.2 GO:0070206 protein trimerization(GO:0070206)
0.0 0.8 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.5 GO:0030728 ovulation(GO:0030728)
0.0 0.5 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0070269 ectopic germ cell programmed cell death(GO:0035234) pyroptosis(GO:0070269)
0.0 2.3 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 10.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly