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ENCODE cell lines, expression (Ernst 2011)

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Results for HOXA6

Z-value: 0.86

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Transcription factors associated with HOXA6

Gene Symbol Gene ID Gene Info
HOXA6
ENSG00000106006.6 HOXA6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v2_chr7_-_27187393_27187393-0.292.8e-01Click!

Activity profile of HOXA6 motif

Sorted Z-values of HOXA6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_53089723 4.25 ENST00000561992.1
ENST00000562512.2
 TCF4
 transcription factor 4
chr17_-_46688334 2.09 ENST00000239165.7
 HOXB7
 homeobox B7
chr10_+_11047259 2.08 ENST00000379261.4
ENST00000416382.2
 CELF2
 CUGBP, Elav-like family member 2
chr2_-_145278475 2.02 ENST00000558170.2
 ZEB2
 zinc finger E-box binding homeobox 2
chr18_-_52989217 1.73 ENST00000570287.2
 TCF4
 transcription factor 4
chr5_-_88179302 1.63 ENST00000504921.2
 MEF2C
 myocyte enhancer factor 2C
chr18_-_52989525 1.60 ENST00000457482.3
 TCF4
 transcription factor 4
chr4_+_41258786 1.49 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_-_91576750 1.33 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
 DCN
 decorin
chr4_+_129730779 1.29 ENST00000226319.6
 PHF17
 jade family PHD finger 1
chr4_+_129730947 1.27 ENST00000452328.2
ENST00000504089.1
 PHF17
 jade family PHD finger 1
chr17_-_56082455 1.26 ENST00000578794.1
 RP11-159D12.5
 Uncharacterized protein
chr18_-_53070913 1.21 ENST00000568186.1
ENST00000564228.1
 TCF4
 transcription factor 4
chr3_+_152017181 1.18 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
 MBNL1
 muscleblind-like splicing regulator 1
chr12_-_91576429 1.16 ENST00000552145.1
ENST00000546745.1
 DCN
 decorin
chr12_-_91576561 1.13 ENST00000547568.2
ENST00000552962.1
 DCN
 decorin
chr18_-_53177984 1.12 ENST00000543082.1
 TCF4
 transcription factor 4
chr3_+_152017360 1.12 ENST00000485910.1
ENST00000463374.1
 MBNL1
 muscleblind-like splicing regulator 1
chr9_+_2159850 1.07 ENST00000416751.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_55095264 1.06 ENST00000257290.5
 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
chr9_+_2015335 1.06 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_69985734 1.00 ENST00000314557.6
ENST00000394351.3
 MITF
 microphthalmia-associated transcription factor
chr2_+_33359646 0.96 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_+_33359687 0.94 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr3_+_69928256 0.82 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr17_-_46682321 0.82 ENST00000225648.3
ENST00000484302.2
 HOXB6
 homeobox B6
chr3_+_69985792 0.82 ENST00000531774.1
 MITF
 microphthalmia-associated transcription factor
chr14_+_61654271 0.81 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
 PRKCH
 protein kinase C, eta
chr3_+_69812877 0.79 ENST00000457080.1
ENST00000328528.6
 MITF
 microphthalmia-associated transcription factor
chr2_-_175711133 0.77 ENST00000409597.1
ENST00000413882.1
 CHN1
 chimerin 1
chr2_-_145277569 0.76 ENST00000303660.4
 ZEB2
 zinc finger E-box binding homeobox 2
chr2_+_66662690 0.75 ENST00000488550.1
 MEIS1
 Meis homeobox 1
chr2_+_66662510 0.73 ENST00000272369.9
ENST00000407092.2
 MEIS1
 Meis homeobox 1
chr11_+_128562372 0.69 ENST00000344954.6
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chrX_+_9431324 0.69 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr8_-_93107443 0.68 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_+_96869165 0.64 ENST00000421109.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr17_-_46671323 0.64 ENST00000239151.5
 HOXB5
 homeobox B5
chr3_+_69812701 0.63 ENST00000472437.1
 MITF
 microphthalmia-associated transcription factor
chr14_-_92413353 0.56 ENST00000556154.1
 FBLN5
 fibulin 5
chr21_-_40033618 0.56 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr9_-_124989804 0.54 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr14_-_92413727 0.53 ENST00000267620.10
 FBLN5
 fibulin 5
chr4_+_160188889 0.51 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_21786179 0.50 ENST00000377113.5
 CASC10
 cancer susceptibility candidate 10
chr9_+_2158485 0.48 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_-_46293378 0.47 ENST00000330430.6
 RCAN2
 regulator of calcineurin 2
chr9_+_2158443 0.45 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_122653630 0.44 ENST00000303924.4
 HAS2
 hyaluronan synthase 2
chr1_+_168250194 0.43 ENST00000367821.3
 TBX19
 T-box 19
chr11_+_128563652 0.43 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr3_+_141106643 0.41 ENST00000514251.1
 ZBTB38
 zinc finger and BTB domain containing 38
chr5_-_88119580 0.41 ENST00000539796.1
 MEF2C
 myocyte enhancer factor 2C
chrX_-_124097620 0.40 ENST00000371130.3
ENST00000422452.2
 TENM1
 teneurin transmembrane protein 1
chr16_-_67517716 0.38 ENST00000290953.2
 AGRP
 agouti related protein homolog (mouse)
chr9_-_124990680 0.36 ENST00000541397.2
ENST00000560485.1
 LHX6
 LIM homeobox 6
chr7_+_28452130 0.35 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chr7_-_14026123 0.34 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
 ETV1
 ets variant 1
chr12_-_102874416 0.34 ENST00000392904.1
ENST00000337514.6
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr21_-_39870339 0.34 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
chr12_-_102874378 0.34 ENST00000456098.1
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr7_-_83824169 0.32 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_123396528 0.32 ENST00000322282.7
ENST00000529750.1
 GRAMD1B
 GRAM domain containing 1B
chr1_+_6105974 0.31 ENST00000378083.3
 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_-_70745575 0.31 ENST00000524945.1
 SLCO5A1
 solute carrier organic anion transporter family, member 5A1
chr11_-_27723158 0.30 ENST00000395980.2
 BDNF
 brain-derived neurotrophic factor
chr17_+_42634844 0.30 ENST00000315323.3
 FZD2
 frizzled family receptor 2
chr7_+_129015484 0.29 ENST00000490911.1
 AHCYL2
 adenosylhomocysteinase-like 2
chr6_-_32157947 0.27 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr12_-_102874102 0.26 ENST00000392905.2
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr18_-_31628558 0.26 ENST00000535384.1
 NOL4
 nucleolar protein 4
chr12_-_102591604 0.26 ENST00000329406.4
 PMCH
 pro-melanin-concentrating hormone
chr5_-_160973649 0.25 ENST00000393959.1
ENST00000517547.1
 GABRB2
 gamma-aminobutyric acid (GABA) A receptor, beta 2
chr13_-_99667960 0.25 ENST00000448493.2
 DOCK9
 dedicator of cytokinesis 9
chr4_-_116034979 0.24 ENST00000264363.2
 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr4_-_41884620 0.24 ENST00000504870.1
 LINC00682
 long intergenic non-protein coding RNA 682
chr13_-_67802549 0.24 ENST00000328454.5
ENST00000377865.2
 PCDH9
 protocadherin 9
chr3_+_173302222 0.24 ENST00000361589.4
 NLGN1
 neuroligin 1
chr11_+_20620946 0.23 ENST00000525748.1
 SLC6A5
 solute carrier family 6 (neurotransmitter transporter), member 5
chr8_-_95449155 0.22 ENST00000481490.2
 FSBP
 fibrinogen silencer binding protein
chr1_-_28527152 0.22 ENST00000321830.5
 AL353354.1
 Uncharacterized protein
chr3_-_57233966 0.22 ENST00000473921.1
ENST00000295934.3
 HESX1
 HESX homeobox 1
chr9_-_13165457 0.21 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
 MPDZ
 multiple PDZ domain protein
chr18_+_32073253 0.21 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA
 dystrobrevin, alpha
chr12_-_14133053 0.21 ENST00000609686.1
 GRIN2B
 glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr17_-_26220366 0.20 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
 LYRM9
RP1-66C13.4
 LYR motif containing 9
Uncharacterized protein
chr6_-_22297730 0.20 ENST00000306482.1
 PRL
 prolactin
chr4_-_72649763 0.20 ENST00000513476.1
 GC
 group-specific component (vitamin D binding protein)
chr12_-_117799446 0.19 ENST00000317775.6
ENST00000344089.3
 NOS1
 nitric oxide synthase 1 (neuronal)
chr15_+_96876340 0.19 ENST00000453270.2
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr12_-_102874330 0.18 ENST00000307046.8
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr1_-_216596738 0.18 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
 USH2A
 Usher syndrome 2A (autosomal recessive, mild)
chr17_-_10372875 0.16 ENST00000255381.2
 MYH4
 myosin, heavy chain 4, skeletal muscle
chr14_+_22977587 0.16 ENST00000390504.1
 TRAJ33
 T cell receptor alpha joining 33
chr5_+_161112754 0.16 ENST00000523217.1
 GABRA6
 gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr7_-_14026063 0.15 ENST00000443608.1
ENST00000438956.1
 ETV1
 ets variant 1
chr15_+_34261089 0.15 ENST00000383263.5
 CHRM5
 cholinergic receptor, muscarinic 5
chr17_-_39623681 0.15 ENST00000225899.3
 KRT32
 keratin 32
chr3_+_88188254 0.15 ENST00000309495.5
 ZNF654
 zinc finger protein 654
chr3_+_1134260 0.15 ENST00000446702.2
ENST00000539053.1
ENST00000350110.2
 CNTN6
 contactin 6
chrX_+_135251835 0.14 ENST00000456445.1
 FHL1
 four and a half LIM domains 1
chr2_+_210444748 0.14 ENST00000392194.1
 MAP2
 microtubule-associated protein 2
chr11_-_8290263 0.14 ENST00000428101.2
 LMO1
 LIM domain only 1 (rhombotin 1)
chr15_-_70390213 0.13 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr9_+_82186872 0.13 ENST00000376544.3
ENST00000376520.4
 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_+_12538594 0.13 ENST00000543710.1
 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_-_216896780 0.13 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
 ESRRG
 estrogen-related receptor gamma
chr2_-_77749474 0.12 ENST00000409093.1
ENST00000409088.3
 LRRTM4
 leucine rich repeat transmembrane neuronal 4
chr7_-_115670804 0.12 ENST00000320239.7
 TFEC
 transcription factor EC
chr7_-_27142290 0.11 ENST00000222718.5
 HOXA2
 homeobox A2
chrX_+_28605516 0.10 ENST00000378993.1
 IL1RAPL1
 interleukin 1 receptor accessory protein-like 1
chr7_-_115670792 0.10 ENST00000265440.7
ENST00000393485.1
 TFEC
 transcription factor EC
chr5_-_59783882 0.10 ENST00000505507.2
ENST00000502484.2
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr15_+_58430368 0.10 ENST00000558772.1
ENST00000219919.4
 AQP9
 aquaporin 9
chr9_+_2717502 0.10 ENST00000382082.3
 KCNV2
 potassium channel, subfamily V, member 2
chr1_+_65730385 0.10 ENST00000263441.7
ENST00000395325.3
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr21_-_35899113 0.10 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
 RCAN1
 regulator of calcineurin 1
chr2_+_210444142 0.09 ENST00000360351.4
ENST00000361559.4
 MAP2
 microtubule-associated protein 2
chr5_+_176811431 0.09 ENST00000512593.1
ENST00000324417.5
 SLC34A1
 solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr5_+_161112563 0.09 ENST00000274545.5
 GABRA6
 gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr6_+_45296048 0.09 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
 RUNX2
 runt-related transcription factor 2
chr1_+_84630053 0.09 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr10_+_115312766 0.09 ENST00000351270.3
 HABP2
 hyaluronan binding protein 2
chr9_-_20622478 0.09 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_92681033 0.08 ENST00000371697.3
 ANKRD1
 ankyrin repeat domain 1 (cardiac muscle)
chr5_+_161494521 0.08 ENST00000356592.3
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chrX_+_16668278 0.08 ENST00000380200.3
 S100G
 S100 calcium binding protein G
chr15_+_48498480 0.07 ENST00000380993.3
ENST00000396577.3
 SLC12A1
 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_+_186265399 0.07 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
 PRG4
 proteoglycan 4
chr6_+_143929307 0.07 ENST00000427704.2
ENST00000305766.6
 PHACTR2
 phosphatase and actin regulator 2
chr5_-_58882219 0.07 ENST00000505453.1
ENST00000360047.5
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr5_-_34043310 0.06 ENST00000231338.7
 C1QTNF3
 C1q and tumor necrosis factor related protein 3
chr13_-_103053946 0.06 ENST00000376131.4
 FGF14
 fibroblast growth factor 14
chr7_-_25268104 0.06 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr22_+_39101728 0.05 ENST00000216044.5
ENST00000484657.1
 GTPBP1
 GTP binding protein 1
chr15_+_80364901 0.05 ENST00000560228.1
ENST00000559835.1
ENST00000559775.1
ENST00000558688.1
ENST00000560392.1
ENST00000560976.1
ENST00000558272.1
ENST00000558390.1
 ZFAND6
 zinc finger, AN1-type domain 6
chr4_-_176733897 0.05 ENST00000393658.2
 GPM6A
 glycoprotein M6A
chr18_+_32173276 0.05 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
 DTNA
 dystrobrevin, alpha
chr6_+_42584847 0.05 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr5_+_161275320 0.05 ENST00000437025.2
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr3_-_54962100 0.04 ENST00000273286.5
 LRTM1
 leucine-rich repeats and transmembrane domains 1
chr15_+_58430567 0.04 ENST00000536493.1
 AQP9
 aquaporin 9
chr13_-_103719196 0.04 ENST00000245312.3
 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr2_+_176987088 0.04 ENST00000249499.6
 HOXD9
 homeobox D9
chr3_-_65583561 0.04 ENST00000460329.2
 MAGI1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_+_161274685 0.04 ENST00000428797.2
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_+_108487245 0.04 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr18_+_59000815 0.04 ENST00000262717.4
 CDH20
 cadherin 20, type 2
chr8_-_93107827 0.04 ENST00000520724.1
ENST00000518844.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107696 0.03 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_161274940 0.03 ENST00000393943.4
 GABRA1
 gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr9_-_14722715 0.03 ENST00000380911.3
 CER1
 cerberus 1, DAN family BMP antagonist
chr12_-_91398796 0.03 ENST00000261172.3
ENST00000551767.1
 EPYC
 epiphycan
chr15_+_71839566 0.03 ENST00000357769.4
 THSD4
 thrombospondin, type I, domain containing 4
chr9_-_73483958 0.02 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
 TRPM3
 transient receptor potential cation channel, subfamily M, member 3
chr5_-_58295712 0.02 ENST00000317118.8
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chrY_-_6742068 0.02 ENST00000215479.5
 AMELY
 amelogenin, Y-linked
chr14_-_54423529 0.02 ENST00000245451.4
ENST00000559087.1
 BMP4
 bone morphogenetic protein 4
chr8_+_9953214 0.01 ENST00000382490.5
 MSRA
 methionine sulfoxide reductase A
chr5_+_161494770 0.01 ENST00000414552.2
ENST00000361925.4
 GABRG2
 gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_+_41174988 0.01 ENST00000372652.1
 NFYC
 nuclear transcription factor Y, gamma
chr8_-_72268889 0.01 ENST00000388742.4
 EYA1
 eyes absent homolog 1 (Drosophila)
chr1_+_206557366 0.00 ENST00000414007.1
ENST00000419187.2
 SRGAP2
 SLIT-ROBO Rho GTPase activating protein 2
chr1_+_87797351 0.00 ENST00000370542.1
 LMO4
 LIM domain only 4
chr8_+_9953061 0.00 ENST00000522907.1
ENST00000528246.1
 MSRA
 methionine sulfoxide reductase A

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 3.1 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 1.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 9.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 14.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.1 PID E2F PATHWAY E2F transcription factor network
0.0 1.1 PID IGF1 PATHWAY IGF1 pathway
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 2.0 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.5 1.5 GO:0007412 axon target recognition(GO:0007412)
0.4 1.1 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 3.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.9 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 1.1 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.4 GO:0021983 pituitary gland development(GO:0021983)
0.2 1.9 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.5 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 2.6 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.3 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 0.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 4.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:1900127 renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 1.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 2.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 10.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0002262 myeloid cell homeostasis(GO:0002262) erythrocyte homeostasis(GO:0034101)
0.0 3.1 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.7 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.0 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.8 9.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.9 GO:0050436 microfibril binding(GO:0050436)
0.4 1.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 2.0 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 3.6 GO:0070888 E-box binding(GO:0070888)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 3.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 2.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 2.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0016594 NMDA glutamate receptor activity(GO:0004972) glycine binding(GO:0016594)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)