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ENCODE cell lines, expression (Ernst 2011)

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Results for HOXC11

Z-value: 0.60

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 HOXC11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC11hg19_v2_chr12_+_54366894_54366922-0.332.1e-01Click!

Activity profile of HOXC11 motif

Sorted Z-values of HOXC11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_46679185 1.94 ENST00000439329.3
 CPB2
 carboxypeptidase B2 (plasma)
chr13_-_46679144 1.92 ENST00000181383.4
 CPB2
 carboxypeptidase B2 (plasma)
chr2_+_228678550 1.80 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chrX_-_105282712 1.46 ENST00000372563.1
 SERPINA7
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chrX_+_107683096 1.27 ENST00000328300.6
ENST00000361603.2
 COL4A5
 collagen, type IV, alpha 5
chr5_-_111091948 1.17 ENST00000447165.2
 NREP
 neuronal regeneration related protein
chr16_-_67978016 1.10 ENST00000264005.5
 LCAT
 lecithin-cholesterol acyltransferase
chr7_-_47579188 1.06 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
 TNS3
 tensin 3
chr7_+_134464414 0.97 ENST00000361901.2
 CALD1
 caldesmon 1
chr6_+_12290586 0.83 ENST00000379375.5
 EDN1
 endothelin 1
chr8_+_26435359 0.81 ENST00000311151.5
 DPYSL2
 dihydropyrimidinase-like 2
chr1_+_229440129 0.78 ENST00000366688.3
 SPHAR
 S-phase response (cyclin related)
chr10_+_114709999 0.78 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_39684550 0.77 ENST00000455635.1
ENST00000361566.3
 KRT19
 keratin 19
chr3_-_79816965 0.77 ENST00000464233.1
 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_-_166930131 0.73 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chr1_-_12677714 0.73 ENST00000376223.2
 DHRS3
 dehydrogenase/reductase (SDR family) member 3
chr14_-_25479811 0.73 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr10_-_13523073 0.69 ENST00000440282.1
 BEND7
 BEN domain containing 7
chr17_-_77924627 0.68 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
 TBC1D16
 TBC1 domain family, member 16
chr16_+_15031300 0.66 ENST00000328085.6
 NPIPA1
 nuclear pore complex interacting protein family, member A1
chr10_+_114710516 0.63 ENST00000542695.1
ENST00000346198.4
 TCF7L2
 transcription factor 7-like 2 (T-cell specific, HMG-box)
chr16_+_16472912 0.57 ENST00000530217.2
 NPIPA7
 nuclear pore complex interacting protein family, member A7
chr1_+_167298281 0.57 ENST00000367862.5
 POU2F1
 POU class 2 homeobox 1
chr16_+_14805546 0.56 ENST00000552140.1
 NPIPA3
 nuclear pore complex interacting protein family, member A3
chr19_+_1440838 0.55 ENST00000594262.1
 AC027307.3
 Uncharacterized protein
chr19_+_49468558 0.53 ENST00000331825.6
 FTL
 ferritin, light polypeptide
chr7_+_134464376 0.53 ENST00000454108.1
ENST00000361675.2
 CALD1
 caldesmon 1
chr16_+_16429787 0.52 ENST00000331436.4
ENST00000541593.1
 AC138969.4
 Protein PKD1P1
chr16_-_21431078 0.48 ENST00000458643.2
 NPIPB3
 nuclear pore complex interacting protein family, member B3
chr16_-_18466642 0.47 ENST00000541810.1
ENST00000531453.2
 RP11-1212A22.4
 LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr7_-_27169801 0.46 ENST00000511914.1
 HOXA4
 homeobox A4
chr2_+_211421262 0.44 ENST00000233072.5
 CPS1
 carbamoyl-phosphate synthase 1, mitochondrial
chr22_+_39916558 0.42 ENST00000337304.2
ENST00000396680.1
 ATF4
 activating transcription factor 4
chr1_+_183774240 0.37 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr19_-_10420459 0.36 ENST00000403352.1
ENST00000403903.3
 ZGLP1
 zinc finger, GATA-like protein 1
chr8_-_18666360 0.35 ENST00000286485.8
 PSD3
 pleckstrin and Sec7 domain containing 3
chrX_-_107682702 0.35 ENST00000372216.4
 COL4A6
 collagen, type IV, alpha 6
chr12_-_24102576 0.32 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
 SOX5
 SRY (sex determining region Y)-box 5
chr8_-_57123815 0.30 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1
 pleiomorphic adenoma gene 1
chr1_+_52682052 0.27 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr7_-_11871815 0.27 ENST00000423059.4
 THSD7A
 thrombospondin, type I, domain containing 7A
chr2_-_207023918 0.26 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr3_+_173116225 0.25 ENST00000457714.1
 NLGN1
 neuroligin 1
chr1_-_237167718 0.25 ENST00000464121.2
 MT1HL1
 metallothionein 1H-like 1
chr13_+_97928395 0.24 ENST00000445661.2
 MBNL2
 muscleblind-like splicing regulator 2
chr2_+_166428839 0.22 ENST00000342316.4
 CSRNP3
 cysteine-serine-rich nuclear protein 3
chr12_-_123201337 0.21 ENST00000528880.2
 HCAR3
 hydroxycarboxylic acid receptor 3
chr7_-_27205136 0.21 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr1_+_87794150 0.19 ENST00000370544.5
 LMO4
 LIM domain only 4
chr1_+_209859510 0.18 ENST00000367028.2
ENST00000261465.1
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr1_+_26485511 0.16 ENST00000374268.3
 FAM110D
 family with sequence similarity 110, member D
chr6_+_108487245 0.16 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr6_+_15246501 0.15 ENST00000341776.2
 JARID2
 jumonji, AT rich interactive domain 2
chrM_+_4431 0.15 ENST00000361453.3
 MT-ND2
 mitochondrially encoded NADH dehydrogenase 2
chr6_-_64029879 0.15 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
 LGSN
 lengsin, lens protein with glutamine synthetase domain
chr8_+_104831554 0.15 ENST00000408894.2
 RIMS2
 regulating synaptic membrane exocytosis 2
chr10_+_26505179 0.14 ENST00000376261.3
 GAD2
 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr9_-_124990680 0.14 ENST00000541397.2
ENST00000560485.1
 LHX6
 LIM homeobox 6
chr6_-_41703952 0.14 ENST00000358871.2
ENST00000403298.4
 TFEB
 transcription factor EB
chr9_-_124989804 0.14 ENST00000373755.2
ENST00000373754.2
 LHX6
 LIM homeobox 6
chr3_+_89156799 0.14 ENST00000452448.2
ENST00000494014.1
 EPHA3
 EPH receptor A3
chr2_-_51259292 0.14 ENST00000401669.2
 NRXN1
 neurexin 1
chr5_-_34043310 0.14 ENST00000231338.7
 C1QTNF3
 C1q and tumor necrosis factor related protein 3
chr4_-_74088800 0.13 ENST00000509867.2
 ANKRD17
 ankyrin repeat domain 17
chr12_+_1800179 0.13 ENST00000357103.4
 ADIPOR2
 adiponectin receptor 2
chr13_-_30424821 0.13 ENST00000380680.4
 UBL3
 ubiquitin-like 3
chr10_+_115614370 0.13 ENST00000369301.3
 NHLRC2
 NHL repeat containing 2
chr17_-_46806540 0.12 ENST00000290295.7
 HOXB13
 homeobox B13
chr7_+_22766766 0.12 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
 IL6
 interleukin 6 (interferon, beta 2)
chr11_-_118305921 0.12 ENST00000532619.1
 RP11-770J1.4
 RP11-770J1.4
chr13_-_46626847 0.11 ENST00000242848.4
ENST00000282007.3
 ZC3H13
 zinc finger CCCH-type containing 13
chr22_+_41697520 0.11 ENST00000352645.4
 ZC3H7B
 zinc finger CCCH-type containing 7B
chr2_-_51259229 0.11 ENST00000405472.3
 NRXN1
 neurexin 1
chr2_+_109204909 0.11 ENST00000393310.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr17_+_7461580 0.10 ENST00000483039.1
ENST00000396542.1
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr10_+_47894023 0.10 ENST00000358474.5
 FAM21B
 family with sequence similarity 21, member B
chr1_-_7913089 0.10 ENST00000361696.5
 UTS2
 urotensin 2
chr2_-_50574856 0.10 ENST00000342183.5
 NRXN1
 neurexin 1
chr13_-_28545276 0.09 ENST00000381020.7
 CDX2
 caudal type homeobox 2
chr1_+_23345930 0.09 ENST00000356634.3
 KDM1A
 lysine (K)-specific demethylase 1A
chr8_+_76452097 0.09 ENST00000396423.2
 HNF4G
 hepatocyte nuclear factor 4, gamma
chr4_+_160188889 0.09 ENST00000264431.4
 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_63606373 0.08 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr8_-_20040638 0.08 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
 SLC18A1
 solute carrier family 18 (vesicular monoamine transporter), member 1
chr1_+_62439037 0.08 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr4_-_107957454 0.07 ENST00000285311.3
 DKK2
 dickkopf WNT signaling pathway inhibitor 2
chr17_-_39646116 0.07 ENST00000328119.6
 KRT36
 keratin 36
chrX_+_99899180 0.07 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr13_+_109248500 0.07 ENST00000356711.2
 MYO16
 myosin XVI
chrX_-_10851762 0.06 ENST00000380785.1
ENST00000380787.1
 MID1
 midline 1 (Opitz/BBB syndrome)
chr1_+_23345943 0.06 ENST00000400181.4
ENST00000542151.1
 KDM1A
 lysine (K)-specific demethylase 1A
chr6_+_31683117 0.06 ENST00000375825.3
ENST00000375824.1
 LY6G6D
 lymphocyte antigen 6 complex, locus G6D
chr7_+_108210012 0.06 ENST00000249356.3
 DNAJB9
 DnaJ (Hsp40) homolog, subfamily B, member 9
chr3_-_45838011 0.06 ENST00000358525.4
ENST00000413781.1
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chr7_+_141811539 0.06 ENST00000550469.2
ENST00000477922.3
 RP11-1220K2.2
 Putative inactive maltase-glucoamylase-like protein LOC93432
chr2_-_209010874 0.06 ENST00000260988.4
 CRYGB
 crystallin, gamma B
chr2_+_177015122 0.05 ENST00000468418.3
 HOXD3
 homeobox D3
chr3_-_45837959 0.05 ENST00000353278.4
ENST00000456124.2
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chr14_+_56127989 0.05 ENST00000555573.1
 KTN1
 kinectin 1 (kinesin receptor)
chr2_-_40739501 0.05 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_-_81399329 0.05 ENST00000453411.1
ENST00000444829.2
 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
chr5_+_145718587 0.04 ENST00000230732.4
 POU4F3
 POU class 4 homeobox 3
chr8_-_20040601 0.04 ENST00000265808.7
ENST00000522513.1
 SLC18A1
 solute carrier family 18 (vesicular monoamine transporter), member 1
chr9_+_105757590 0.04 ENST00000374798.3
ENST00000487798.1
 CYLC2
 cylicin, basic protein of sperm head cytoskeleton 2
chr8_+_134203273 0.03 ENST00000250160.6
 WISP1
 WNT1 inducible signaling pathway protein 1
chr2_+_27440229 0.03 ENST00000264705.4
ENST00000403525.1
 CAD
 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr11_-_27723158 0.03 ENST00000395980.2
 BDNF
 brain-derived neurotrophic factor
chr1_+_209878182 0.03 ENST00000367027.3
 HSD11B1
 hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_151217166 0.03 ENST00000496004.1
 RHEB
 Ras homolog enriched in brain
chr17_+_7533439 0.03 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
 SHBG
 sex hormone-binding globulin
chr2_+_176987088 0.02 ENST00000249499.6
 HOXD9
 homeobox D9
chr3_+_89156674 0.02 ENST00000336596.2
 EPHA3
 EPH receptor A3
chr16_-_2314222 0.01 ENST00000566397.1
 RNPS1
 RNA binding protein S1, serine-rich domain
chr20_+_4702548 0.01 ENST00000305817.2
 PRND
 prion protein 2 (dublet)
chr8_-_59412717 0.01 ENST00000301645.3
 CYP7A1
 cytochrome P450, family 7, subfamily A, polypeptide 1
chr17_+_7461613 0.00 ENST00000438470.1
ENST00000436057.1
 TNFSF13
 tumor necrosis factor (ligand) superfamily, member 13
chr2_-_136678123 0.00 ENST00000422708.1
 DARS
 aspartyl-tRNA synthetase
chr2_+_210444142 0.00 ENST00000360351.4
ENST00000361559.4
 MAP2
 microtubule-associated protein 2
chr8_+_134203303 0.00 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
 WISP1
 WNT1 inducible signaling pathway protein 1

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0043194 voltage-gated sodium channel complex(GO:0001518) axon initial segment(GO:0043194)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 1.8 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 0.8 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 1.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.3 0.8 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 1.4 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.4 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.4 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.5 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.4 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.7 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.3 GO:0021853 cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.9 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.8 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.7 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 1.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 0.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway