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ENCODE cell lines, expression (Ernst 2011)

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Results for HOXC13

Z-value: 0.99

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
HOXC13
ENSG00000123364.3 HOXC13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXC13hg19_v2_chr12_+_54332535_54332636-0.117.0e-01Click!

Activity profile of HOXC13 motif

Sorted Z-values of HOXC13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_33041378 3.40 ENST00000428995.1
 HLA-DPA1
 major histocompatibility complex, class II, DP alpha 1
chr1_+_158979680 2.36 ENST00000368131.4
ENST00000340979.6
 IFI16
 interferon, gamma-inducible protein 16
chr1_+_158979686 2.32 ENST00000368132.3
ENST00000295809.7
 IFI16
 interferon, gamma-inducible protein 16
chr1_+_174128639 1.99 ENST00000251507.4
 RABGAP1L
 RAB GTPase activating protein 1-like
chr1_+_192544857 1.79 ENST00000367459.3
ENST00000469578.2
 RGS1
 regulator of G-protein signaling 1
chr10_+_70847852 1.77 ENST00000242465.3
 SRGN
 serglycin
chr4_-_71532339 1.77 ENST00000254801.4
 IGJ
 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_174844645 1.68 ENST00000486220.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr18_+_61554932 1.65 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr3_+_159557637 1.62 ENST00000445224.2
 SCHIP1
 schwannomin interacting protein 1
chr22_+_23101182 1.59 ENST00000390312.2
 IGLV2-14
 immunoglobulin lambda variable 2-14
chr8_-_95274536 1.56 ENST00000297596.2
ENST00000396194.2
 GEM
 GTP binding protein overexpressed in skeletal muscle
chr9_-_88715044 1.52 ENST00000388711.3
ENST00000466178.1
 GOLM1
 golgi membrane protein 1
chr12_+_75874580 1.48 ENST00000456650.3
 GLIPR1
 GLI pathogenesis-related 1
chr14_-_106963409 1.43 ENST00000390621.2
 IGHV1-45
 immunoglobulin heavy variable 1-45
chr1_+_158815588 1.38 ENST00000438394.1
 MNDA
 myeloid cell nuclear differentiation antigen
chr15_+_71185148 1.29 ENST00000443425.2
ENST00000560755.1
 LRRC49
 leucine rich repeat containing 49
chr16_+_12059050 1.26 ENST00000396495.3
 TNFRSF17
 tumor necrosis factor receptor superfamily, member 17
chr1_-_169680745 1.23 ENST00000236147.4
 SELL
 selectin L
chr15_+_71228826 1.19 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49
 leucine rich repeat containing 49
chr22_+_38142235 1.15 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
 TRIOBP
 TRIO and F-actin binding protein
chr12_-_91539918 1.12 ENST00000548218.1
 DCN
 decorin
chr16_+_33605231 1.11 ENST00000570121.2
 IGHV3OR16-12
 immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr14_-_106668095 1.11 ENST00000390606.2
 IGHV3-20
 immunoglobulin heavy variable 3-20
chr9_-_88714421 1.10 ENST00000388712.3
 GOLM1
 golgi membrane protein 1
chr2_+_33359687 1.10 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
 LTBP1
 latent transforming growth factor beta binding protein 1
chr2_+_33359646 1.09 ENST00000390003.4
ENST00000418533.2
 LTBP1
 latent transforming growth factor beta binding protein 1
chr15_+_71184931 1.09 ENST00000560369.1
ENST00000260382.5
 LRRC49
 leucine rich repeat containing 49
chr6_-_32784687 1.07 ENST00000447394.1
ENST00000438763.2
 HLA-DOB
 major histocompatibility complex, class II, DO beta
chr13_-_46964177 1.01 ENST00000389908.3
 KIAA0226L
 KIAA0226-like
chrX_+_13707235 1.01 ENST00000464506.1
 RAB9A
 RAB9A, member RAS oncogene family
chr18_-_52989217 0.98 ENST00000570287.2
 TCF4
 transcription factor 4
chr18_-_52989525 0.97 ENST00000457482.3
 TCF4
 transcription factor 4
chr2_-_225811747 0.96 ENST00000409592.3
 DOCK10
 dedicator of cytokinesis 10
chr5_+_150020214 0.93 ENST00000307662.4
 SYNPO
 synaptopodin
chr10_-_79398250 0.90 ENST00000286627.5
 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr6_-_112080256 0.87 ENST00000462856.2
ENST00000229471.4
 FYN
 FYN oncogene related to SRC, FGR, YES
chr1_+_43766642 0.85 ENST00000372476.3
 TIE1
 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_-_89591749 0.82 ENST00000370466.3
 GBP2
 guanylate binding protein 2, interferon-inducible
chr12_-_91546926 0.81 ENST00000550758.1
 DCN
 decorin
chr12_-_4647606 0.80 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
 C12orf4
 chromosome 12 open reading frame 4
chr7_-_41742697 0.77 ENST00000242208.4
 INHBA
 inhibin, beta A
chr10_+_13628933 0.76 ENST00000417658.1
ENST00000320054.4
 PRPF18
 pre-mRNA processing factor 18
chr14_-_106725723 0.73 ENST00000390609.2
 IGHV3-23
 immunoglobulin heavy variable 3-23
chr12_-_92539614 0.68 ENST00000256015.3
 BTG1
 B-cell translocation gene 1, anti-proliferative
chr10_-_6019984 0.67 ENST00000525219.2
 IL15RA
 interleukin 15 receptor, alpha
chr7_+_80275953 0.64 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
 CD36
 CD36 molecule (thrombospondin receptor)
chr5_-_146781153 0.64 ENST00000520473.1
 DPYSL3
 dihydropyrimidinase-like 3
chr18_-_5544241 0.64 ENST00000341928.2
ENST00000540638.2
 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
chr21_+_37442239 0.60 ENST00000530908.1
ENST00000290349.6
ENST00000439427.2
ENST00000399191.3
 CBR1
 carbonyl reductase 1
chrX_-_135338503 0.60 ENST00000370663.5
 MAP7D3
 MAP7 domain containing 3
chr9_-_5304432 0.58 ENST00000416837.1
ENST00000308420.3
 RLN2
 relaxin 2
chr9_-_37034028 0.57 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
 PAX5
 paired box 5
chr4_-_120243545 0.55 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr7_+_80275752 0.52 ENST00000419819.2
 CD36
 CD36 molecule (thrombospondin receptor)
chr8_-_93029865 0.52 ENST00000422361.2
 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_102953608 0.50 ENST00000311734.2
ENST00000409584.1
 IL1RL1
 interleukin 1 receptor-like 1
chr19_+_13858593 0.46 ENST00000221554.8
 CCDC130
 coiled-coil domain containing 130
chrX_+_119737806 0.46 ENST00000371317.5
 MCTS1
 malignant T cell amplified sequence 1
chr1_+_84630645 0.45 ENST00000394839.2
 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
chr6_-_46922659 0.44 ENST00000265417.7
 GPR116
 G protein-coupled receptor 116
chr2_+_210444142 0.42 ENST00000360351.4
ENST00000361559.4
 MAP2
 microtubule-associated protein 2
chr3_-_172241250 0.41 ENST00000420541.2
ENST00000241261.2
 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
chr19_-_45982076 0.41 ENST00000423698.2
 ERCC1
 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_+_153003671 0.41 ENST00000307098.4
 SPRR1B
 small proline-rich protein 1B
chr19_-_11456935 0.40 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
 TMEM205
RAB3D
 transmembrane protein 205
RAB3D, member RAS oncogene family
chr19_-_54619006 0.39 ENST00000391759.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr9_-_95244781 0.39 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
 ASPN
 asporin
chr15_+_79166065 0.38 ENST00000559690.1
ENST00000559158.1
 MORF4L1
 mortality factor 4 like 1
chr21_-_27423339 0.38 ENST00000415997.1
 APP
 amyloid beta (A4) precursor protein
chr10_-_79397740 0.37 ENST00000372440.1
ENST00000480683.1
 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_79398127 0.37 ENST00000372443.1
 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_118797475 0.37 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3
 TAO kinase 3
chr9_-_2844058 0.36 ENST00000397885.2
 KIAA0020
 KIAA0020
chr19_-_54618650 0.35 ENST00000391757.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr6_+_29426230 0.35 ENST00000442615.1
 OR2H1
 olfactory receptor, family 2, subfamily H, member 1
chr7_+_80275621 0.34 ENST00000426978.1
ENST00000432207.1
 CD36
 CD36 molecule (thrombospondin receptor)
chr4_-_69536346 0.32 ENST00000338206.5
 UGT2B15
 UDP glucuronosyltransferase 2 family, polypeptide B15
chr3_-_123339418 0.31 ENST00000583087.1
 MYLK
 myosin light chain kinase
chr1_-_67266939 0.31 ENST00000304526.2
 INSL5
 insulin-like 5
chr7_-_76255444 0.31 ENST00000454397.1
 POMZP3
 POM121 and ZP3 fusion
chr10_-_70287172 0.31 ENST00000539557.1
 SLC25A16
 solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr3_-_46037299 0.30 ENST00000296137.2
 FYCO1
 FYVE and coiled-coil domain containing 1
chr11_-_102576537 0.30 ENST00000260229.4
 MMP27
 matrix metallopeptidase 27
chr3_-_98241760 0.29 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
 CLDND1
 claudin domain containing 1
chr12_+_67663056 0.27 ENST00000545606.1
 CAND1
 cullin-associated and neddylation-dissociated 1
chr14_-_106816253 0.27 ENST00000390615.2
 IGHV3-33
 immunoglobulin heavy variable 3-33
chr3_+_101498269 0.26 ENST00000491511.2
 NXPE3
 neurexophilin and PC-esterase domain family, member 3
chr3_-_123339343 0.26 ENST00000578202.1
 MYLK
 myosin light chain kinase
chr19_-_18632861 0.25 ENST00000262809.4
 ELL
 elongation factor RNA polymerase II
chr10_-_70287231 0.24 ENST00000609923.1
 SLC25A16
 solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr5_-_79287060 0.23 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
 MTX3
 metaxin 3
chr22_-_18111499 0.23 ENST00000413576.1
ENST00000399796.2
ENST00000399798.2
ENST00000253413.5
 ATP6V1E1
 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
chr22_-_32808194 0.21 ENST00000451746.2
ENST00000216038.5
 RTCB
 RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr12_-_52828147 0.20 ENST00000252245.5
 KRT75
 keratin 75
chr5_-_180076580 0.20 ENST00000502649.1
 FLT4
 fms-related tyrosine kinase 4
chr3_+_129159039 0.20 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
 IFT122
 intraflagellar transport 122 homolog (Chlamydomonas)
chr2_-_86850949 0.20 ENST00000237455.4
 RNF103
 ring finger protein 103
chr15_-_78538025 0.20 ENST00000560817.1
 ACSBG1
 acyl-CoA synthetase bubblegum family member 1
chr11_+_7618413 0.20 ENST00000528883.1
 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_101170563 0.19 ENST00000520508.1
ENST00000388798.2
 SPAG1
 sperm associated antigen 1
chr17_-_8286484 0.19 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
 RPL26
 ribosomal protein L26
chr1_-_155880672 0.19 ENST00000609492.1
ENST00000368322.3
 RIT1
 Ras-like without CAAX 1
chr2_+_162016804 0.18 ENST00000392749.2
ENST00000440506.1
 TANK
 TRAF family member-associated NFKB activator
chr13_+_34392185 0.18 ENST00000380071.3
 RFC3
 replication factor C (activator 1) 3, 38kDa
chr12_-_57630873 0.17 ENST00000556732.1
 NDUFA4L2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr12_+_15475331 0.16 ENST00000281171.4
 PTPRO
 protein tyrosine phosphatase, receptor type, O
chr10_+_52750930 0.16 ENST00000401604.2
 PRKG1
 protein kinase, cGMP-dependent, type I
chr14_+_22409308 0.15 ENST00000390441.2
 TRAV9-2
 T cell receptor alpha variable 9-2
chr5_+_169010638 0.15 ENST00000265295.4
ENST00000506574.1
ENST00000515224.1
ENST00000508247.1
ENST00000513941.1
 SPDL1
 spindle apparatus coiled-coil protein 1
chr15_-_44069741 0.15 ENST00000319359.3
 ELL3
 elongation factor RNA polymerase II-like 3
chr10_+_94352956 0.15 ENST00000260731.3
 KIF11
 kinesin family member 11
chr6_+_29141311 0.14 ENST00000377167.2
 OR2J2
 olfactory receptor, family 2, subfamily J, member 2
chr3_-_126373929 0.14 ENST00000523403.1
ENST00000524230.2
 TXNRD3
 thioredoxin reductase 3
chr5_-_169725231 0.14 ENST00000046794.5
 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_56769382 0.14 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
 TEX14
 testis expressed 14
chr3_+_100428268 0.14 ENST00000240851.4
 TFG
 TRK-fused gene
chr3_-_125775629 0.13 ENST00000383598.2
 SLC41A3
 solute carrier family 41, member 3
chr3_+_100428316 0.13 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
 TFG
 TRK-fused gene
chr14_+_96722539 0.13 ENST00000553356.1
 BDKRB1
 bradykinin receptor B1
chr11_-_85376121 0.13 ENST00000527447.1
 CREBZF
 CREB/ATF bZIP transcription factor
chr11_+_62037622 0.12 ENST00000227918.2
ENST00000525380.1
 SCGB2A2
 secretoglobin, family 2A, member 2
chr5_+_140248518 0.12 ENST00000398640.2
 PCDHA11
 protocadherin alpha 11
chr3_+_100428188 0.12 ENST00000418917.2
ENST00000490574.1
 TFG
 TRK-fused gene
chr10_-_69455873 0.11 ENST00000433211.2
 CTNNA3
 catenin (cadherin-associated protein), alpha 3
chr1_+_55107449 0.11 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
 MROH7
 maestro heat-like repeat family member 7
chr19_-_6279932 0.11 ENST00000252674.7
 MLLT1
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr2_+_162016916 0.11 ENST00000405852.1
 TANK
 TRAF family member-associated NFKB activator
chr22_+_32439019 0.11 ENST00000266088.4
 SLC5A1
 solute carrier family 5 (sodium/glucose cotransporter), member 1
chr15_+_85523671 0.11 ENST00000310298.4
ENST00000557957.1
 PDE8A
 phosphodiesterase 8A
chr1_-_47407111 0.11 ENST00000371904.4
 CYP4A11
 cytochrome P450, family 4, subfamily A, polypeptide 11
chr17_+_29664830 0.11 ENST00000444181.2
ENST00000417592.2
 NF1
 neurofibromin 1
chr10_+_51549498 0.10 ENST00000358559.2
ENST00000298239.6
 MSMB
 microseminoprotein, beta-
chr11_+_60995849 0.10 ENST00000537932.1
 PGA4
 pepsinogen 4, group I (pepsinogen A)
chr1_-_150208412 0.10 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_+_101569696 0.10 ENST00000597120.1
 AC008948.1
 AC008948.1
chr1_+_17559776 0.09 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
 PADI1
 peptidyl arginine deiminase, type I
chr6_-_75953484 0.09 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
 COX7A2
 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr21_+_39628655 0.09 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr6_-_49681235 0.08 ENST00000339139.4
 CRISP2
 cysteine-rich secretory protein 2
chr12_-_47473425 0.08 ENST00000550413.1
 AMIGO2
 adhesion molecule with Ig-like domain 2
chr1_-_86174065 0.07 ENST00000370574.3
ENST00000431532.2
 ZNHIT6
 zinc finger, HIT-type containing 6
chr6_-_146057144 0.07 ENST00000367519.3
 EPM2A
 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
chr12_-_114841703 0.07 ENST00000526441.1
 TBX5
 T-box 5
chr2_+_89986318 0.07 ENST00000491977.1
 IGKV2D-29
 immunoglobulin kappa variable 2D-29
chr1_-_55266926 0.06 ENST00000371276.4
 TTC22
 tetratricopeptide repeat domain 22
chr19_+_21106081 0.06 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
 ZNF85
 zinc finger protein 85
chr12_+_4758264 0.05 ENST00000266544.5
 NDUFA9
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr19_-_23869999 0.05 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
 ZNF675
 zinc finger protein 675
chr16_-_68033356 0.05 ENST00000393847.1
ENST00000573808.1
ENST00000572624.1
 DPEP2
 dipeptidase 2
chr11_+_49050504 0.05 ENST00000332682.7
 TRIM49B
 tripartite motif containing 49B
chr4_+_71248795 0.04 ENST00000304915.3
 SMR3B
 submaxillary gland androgen regulated protein 3B
chr1_-_150208498 0.04 ENST00000314136.8
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_+_72052983 0.03 ENST00000358550.2
 SIPA1L1
 signal-induced proliferation-associated 1 like 1
chr9_+_137979506 0.03 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
 OLFM1
 olfactomedin 1
chr17_+_3118915 0.03 ENST00000304094.1
 OR1A1
 olfactory receptor, family 1, subfamily A, member 1
chrX_-_100129128 0.03 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
 NOX1
 NADPH oxidase 1
chr4_-_170533723 0.03 ENST00000510533.1
ENST00000439128.2
ENST00000511633.1
ENST00000512193.1
ENST00000507142.1
 NEK1
 NIMA-related kinase 1
chr2_-_37384175 0.02 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
 EIF2AK2
 eukaryotic translation initiation factor 2-alpha kinase 2
chr1_+_47603109 0.02 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
 CYP4A22
 cytochrome P450, family 4, subfamily A, polypeptide 22
chr2_+_172778952 0.02 ENST00000392584.1
ENST00000264108.4
 HAT1
 histone acetyltransferase 1
chr4_+_110749143 0.02 ENST00000317735.4
 RRH
 retinal pigment epithelium-derived rhodopsin homolog
chr4_+_106631966 0.02 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
 GSTCD
 glutathione S-transferase, C-terminal domain containing
chr17_-_39637392 0.02 ENST00000246639.2
ENST00000393989.1
 KRT35
 keratin 35
chr5_-_64920115 0.02 ENST00000381018.3
ENST00000274327.7
 TRIM23
 tripartite motif containing 23
chr6_-_33239612 0.02 ENST00000482399.1
ENST00000445902.2
 VPS52
 vacuolar protein sorting 52 homolog (S. cerevisiae)
chr17_-_39526052 0.02 ENST00000251646.3
 KRT33B
 keratin 33B
chr17_-_3496171 0.02 ENST00000399756.4
 TRPV1
 transient receptor potential cation channel, subfamily V, member 1
chr11_+_3011093 0.02 ENST00000332881.2
 AC131971.1
 HCG1782999; PRO0943; Uncharacterized protein
chr6_-_33239712 0.01 ENST00000436044.2
 VPS52
 vacuolar protein sorting 52 homolog (S. cerevisiae)
chr11_-_124670550 0.01 ENST00000239614.4
 MSANTD2
 Myb/SANT-like DNA-binding domain containing 2
chr12_-_53207842 0.01 ENST00000458244.2
 KRT4
 keratin 4
chr4_+_122722466 0.01 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
 EXOSC9
 exosome component 9
chr20_+_36946029 0.01 ENST00000417318.1
 BPI
 bactericidal/permeability-increasing protein
chr2_+_48796120 0.01 ENST00000394754.1
 STON1-GTF2A1L
 STON1-GTF2A1L readthrough
chr17_-_46806540 0.00 ENST00000290295.7
 HOXB13
 homeobox B13

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 1.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 0.8 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 0.8 GO:0071030 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.2 2.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.2 GO:0030047 actin modification(GO:0030047)
0.2 1.5 GO:0072564 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.0 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 4.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.9 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.4 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1 4.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 1.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.2 GO:0035720 signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 3.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 3.0 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 1.3 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.4 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.8 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 1.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 2.4 GO:0006997 nucleus organization(GO:0006997)
0.0 0.7 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0050436 microfibril binding(GO:0050436)
0.3 4.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 1.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.6 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 4.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 4.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 2.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 4.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 3.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.9 GO:0003823 antigen binding(GO:0003823)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 0.8 GO:0071020 post-spliceosomal complex(GO:0071020)
0.2 4.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.2 GO:0042588 zymogen granule(GO:0042588)
0.1 2.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 4.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.4 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.1 1.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 1.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 4.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network