ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
HOXD1 Links Ensembl NCBI GeneCards UniProt	ENSG00000128645.11	HOXD1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXD1	hg19_v2_chr2_+_177053307_177053402	-0.46	7.6e-02	Click!

View svg image
View png image

Promoter	Score	Transcript	Gene	Gene Info
chr15_-_55563072	1.14	ENST00000567380.1 ENST00000565972.1 ENST00000569493.1	RAB27A	RAB27A, member RAS oncogene family
chr11_-_62521614	1.12	ENST00000527994.1 ENST00000394807.3	ZBTB3	zinc finger and BTB domain containing 3
chr15_-_55562479	1.07	ENST00000564609.1	RAB27A	RAB27A, member RAS oncogene family
chr8_-_49834299	1.02	ENST00000396822.1	SNAI2	snail family zinc finger 2
chr4_-_25865159	1.00	ENST00000502949.1 ENST00000264868.5 ENST00000513691.1 ENST00000514872.1	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr12_+_29376673	0.97	ENST00000547116.1	FAR2	fatty acyl CoA reductase 2
chr12_+_29376592	0.95	ENST00000182377.4	FAR2	fatty acyl CoA reductase 2
chr3_-_151034734	0.93	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr8_-_49833978	0.91	ENST00000020945.1	SNAI2	snail family zinc finger 2
chr11_-_102651343	0.87	ENST00000279441.4 ENST00000539681.1	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr12_-_10022735	0.72	ENST00000228438.2	CLEC2B	C-type lectin domain family 2, member B
chr15_-_55562582	0.72	ENST00000396307.2	RAB27A	RAB27A, member RAS oncogene family
chr11_-_71823266	0.62	ENST00000538919.1 ENST00000539395.1 ENST00000542531.1	ANAPC15	anaphase promoting complex subunit 15
chr12_+_28410128	0.58	ENST00000381259.1 ENST00000381256.1	CCDC91	coiled-coil domain containing 91
chr5_+_66300446	0.58	ENST00000261569.7	MAST4	microtubule associated serine/threonine kinase family member 4
chrX_+_43515467	0.55	ENST00000338702.3 ENST00000542639.1	MAOA	monoamine oxidase A
chr11_-_71823796	0.52	ENST00000545680.1 ENST00000543587.1 ENST00000538393.1 ENST00000535234.1 ENST00000227618.4 ENST00000535503.1	ANAPC15	anaphase promoting complex subunit 15
chr11_-_71823715	0.47	ENST00000545944.1 ENST00000502597.2	ANAPC15	anaphase promoting complex subunit 15
chr7_-_81399438	0.45	ENST00000222390.5	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_+_111717600	0.45	ENST00000273368.4	TAGLN3	transgelin 3
chr7_-_81399329	0.45	ENST00000453411.1 ENST00000444829.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_+_114827818	0.41	ENST00000420625.2	PLS3	plastin 3
chr3_+_111717511	0.41	ENST00000478951.1 ENST00000393917.2	TAGLN3	transgelin 3
chr15_-_37393406	0.37	ENST00000338564.5 ENST00000558313.1 ENST00000340545.5	MEIS2	Meis homeobox 2
chr3_+_111718036	0.35	ENST00000455401.2	TAGLN3	transgelin 3
chr12_-_118797475	0.35	ENST00000541786.1 ENST00000419821.2 ENST00000541878.1	TAOK3	TAO kinase 3
chr3_-_126327398	0.35	ENST00000383572.2	TXNRD3NB	thioredoxin reductase 3 neighbor
chr5_+_148737562	0.34	ENST00000274569.4	PCYOX1L	prenylcysteine oxidase 1 like
chr7_-_81399411	0.30	ENST00000423064.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399355	0.25	ENST00000457544.2	HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_-_164796269	0.22	ENST00000264382.3	SI	sucrase-isomaltase (alpha-glucosidase)
chr3_+_111718173	0.22	ENST00000494932.1	TAGLN3	transgelin 3
chr18_-_33709268	0.16	ENST00000269187.5 ENST00000590986.1 ENST00000440549.2	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chrX_+_77154935	0.15	ENST00000481445.1	COX7B	cytochrome c oxidase subunit VIIb
chr11_+_73498898	0.10	ENST00000535529.1 ENST00000497094.2 ENST00000411840.2 ENST00000535277.1 ENST00000398483.3 ENST00000542303.1	MRPL48	mitochondrial ribosomal protein L48
chr2_+_11682790	0.09	ENST00000389825.3 ENST00000381483.2	GREB1	growth regulation by estrogen in breast cancer 1
chr7_-_99716952	0.09	ENST00000523306.1 ENST00000344095.4 ENST00000417349.1 ENST00000493322.1 ENST00000520135.1 ENST00000418432.2 ENST00000460673.2 ENST00000452041.1 ENST00000452438.2 ENST00000451699.1 ENST00000453269.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr5_+_176811431	0.08	ENST00000512593.1 ENST00000324417.5	SLC34A1	solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr4_+_144354644	0.06	ENST00000512843.1	GAB1	GRB2-associated binding protein 1
chr3_-_101039402	0.04	ENST00000193391.7	IMPG2	interphotoreceptor matrix proteoglycan 2
chr4_-_119759795	0.04	ENST00000419654.2	SEC24D	SEC24 family member D
chr17_-_10372875	0.03	ENST00000255381.2	MYH4	myosin, heavy chain 4, skeletal muscle
chr10_+_18549645	0.02	ENST00000396576.2	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr4_-_74486347	0.02	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr9_-_5339873	0.01	ENST00000223862.1 ENST00000223858.4	RLN1	relaxin 1
chr4_-_74486217	0.01	ENST00000335049.5 ENST00000307439.5	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr3_+_129247479	0.01	ENST00000296271.3	RHO	rhodopsin
chr14_+_32798547	0.01	ENST00000557354.1 ENST00000557102.1 ENST00000557272.1	AKAP6	A kinase (PRKA) anchor protein 6
chr11_-_95657231	0.00	ENST00000409459.1 ENST00000352297.7 ENST00000393223.3 ENST00000346299.5	MTMR2	myotubularin related protein 2

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.6	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	0.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.0	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.1	2.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.6	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	2.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	1.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.5	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	1.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.6	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.6	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	2.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.5	GO:0071461	cellular response to redox state(GO:0071461)
0.5	1.4	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.4	1.8	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.3	1.0	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.3	0.8	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.2	0.7	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2	2.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2	1.3	GO:0019064	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2	1.0	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.2	1.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.2	0.6	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2	1.0	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.4	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1	0.4	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	1.3	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.1	0.4	GO:0090149	synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.1	0.4	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
0.1	0.6	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.3	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1	0.5	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.1	0.3	GO:0009107	lipoate biosynthetic process(GO:0009107)
0.1	0.4	GO:0042360	vitamin E metabolic process(GO:0042360)
0.1	0.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.8	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.5	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.1	0.8	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	1.6	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.5	GO:2000035	regulation of stem cell division(GO:2000035)
0.1	0.3	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.1	0.4	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1	0.4	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	0.6	GO:0000012	single strand break repair(GO:0000012)
0.1	0.5	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.4	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.1	0.5	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.4	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1	0.2	GO:0072302	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.6	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1	0.3	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	2.5	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.0	0.1	GO:1903939	negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0	0.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	0.2	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.0	0.2	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.0	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	1.5	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	1.8	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.4	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	1.5	GO:0014904	myotube cell development(GO:0014904)
0.0	0.5	GO:0015671	oxygen transport(GO:0015671)
0.0	0.5	GO:0035878	nail development(GO:0035878)
0.0	0.2	GO:0061107	prostate gland stromal morphogenesis(GO:0060741) seminal vesicle development(GO:0061107)
0.0	0.1	GO:0021997	response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.0	0.1	GO:2000253	positive regulation of feeding behavior(GO:2000253)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.7	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.6	GO:0030903	notochord development(GO:0030903)
0.0	0.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.2	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.3	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.3	GO:1902951	negative regulation of dendritic spine maintenance(GO:1902951)
0.0	0.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	1.6	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
0.0	0.3	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	1.1	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.0	0.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.8	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:0044209	AMP salvage(GO:0044209)
0.0	0.1	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0	0.4	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.4	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.3	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.5	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:2000254	regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0	0.1	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0	0.2	GO:0014029	neural crest formation(GO:0014029)
0.0	0.2	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.2	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	1.0	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.4	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0	0.4	GO:0060065	uterus development(GO:0060065)
0.0	0.1	GO:0030885	regulation of myeloid dendritic cell activation(GO:0030885)
0.0	0.2	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.6	GO:0051031	tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	1.6	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.4	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.2	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	1.6	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.2	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.9	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.4	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.0	0.4	GO:0007094	mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0	0.4	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	3.0	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.2	GO:0042448	progesterone metabolic process(GO:0042448)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1	2.9	GO:0031489	myosin V binding(GO:0031489)
0.1	0.2	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.3	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	1.4	GO:0042056	chemoattractant activity(GO:0042056)
0.0	1.9	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	12.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	26.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.3	11.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3	6.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	5.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2	12.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	4.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	2.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.4	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	4.4	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.6	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.6	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.4	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	1.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.8	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	2.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.9	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.3	1.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2	1.2	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2	3.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.7	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.7	GO:0048539	immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.1	0.8	GO:0070560	protein secretion by platelet(GO:0070560)
0.1	2.5	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.6	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1	0.6	GO:0051622	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1	0.6	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.4	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.4	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.1	0.3	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1	0.2	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.2	GO:1905205	positive regulation of connective tissue replacement(GO:1905205)
0.1	0.3	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.1	0.3	GO:0032053	ciliary basal body organization(GO:0032053)
0.1	0.6	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	0.6	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.2	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1	0.3	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1	0.3	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.1	0.3	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.2	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.3	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.0	4.2	GO:0042100	B cell proliferation(GO:0042100)
0.0	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0	0.8	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0	0.1	GO:1903674	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0	0.3	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.1	GO:0006711	estrogen catabolic process(GO:0006711)
0.0	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	1.7	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.3	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	1.4	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.2	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.1	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.0	0.1	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0	0.1	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.0	0.6	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0	0.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.0	0.0	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	2.1	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.2	GO:0070986	left/right axis specification(GO:0070986)
0.0	0.1	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.2	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0	0.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:0030822	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0	0.2	GO:0014848	urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848)
0.0	0.0	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.0	0.1	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0030805	regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.0	0.1	GO:0009804	coumarin metabolic process(GO:0009804)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.3	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.1	GO:0070885	positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.2	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	1.5	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	0.0	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	5.8	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	0.7	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.2	2.3	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.9	GO:0052655	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1	0.6	GO:0051373	FATZ binding(GO:0051373)
0.1	0.4	GO:0004819	glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.6	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1	1.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0016749	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1	0.5	GO:0070728	leucine binding(GO:0070728)
0.1	0.3	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.4	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.3	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.2	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.0	0.2	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.4	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	1.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.3	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.0	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.4	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	1.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	1.0	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0051870	methotrexate binding(GO:0051870)
0.0	0.4	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.1	GO:0035276	ethanol binding(GO:0035276)
0.0	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.0	0.1	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.0	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	0.1	GO:0004905	type I interferon receptor activity(GO:0004905)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.6	GO:0031489	myosin V binding(GO:0031489)
0.0	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0051120	hepoxilin A3 synthase activity(GO:0051120)
0.0	0.1	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.4	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.1	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.3	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.3	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.6	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.4	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.4	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.4	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	18.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	12.3	NABA COLLAGENS	Genes encoding collagen proteins
0.2	16.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	9.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	10.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	2.0	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	5.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	3.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	1.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	2.2	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	11.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	1.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.4	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	2.0	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	2.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	2.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.6	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.8	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	1.3	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.2	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	4.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.9	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.2	5.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.2	0.6	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	0.6	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1	0.2	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.1	1.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.1	0.3	GO:0089701	U2AF(GO:0089701)
0.0	0.3	GO:0097209	epidermal lamellar body(GO:0097209)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0043291	RAVE complex(GO:0043291)
0.0	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	3.9	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	1.7	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.3	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.3	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.1	GO:1990037	Lewy body core(GO:1990037)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	4.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.5	GO:0001533	cornified envelope(GO:0001533)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:0005588	collagen type V trimer(GO:0005588)
1.4	21.7	GO:0030478	actin cap(GO:0030478)
1.1	16.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6	1.9	GO:0043511	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.6	5.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.5	6.5	GO:0005577	fibrinogen complex(GO:0005577)
0.4	1.5	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.2	2.5	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.2	1.7	GO:0044326	dendritic spine neck(GO:0044326)
0.2	0.7	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2	1.6	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.2	0.9	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.2	1.6	GO:1990111	spermatoproteasome complex(GO:1990111)
0.2	4.3	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	3.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	1.8	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	2.3	GO:0005687	U4 snRNP(GO:0005687)
0.1	4.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	7.3	GO:0001533	cornified envelope(GO:0001533)
0.1	4.2	GO:0030673	axolemma(GO:0030673)
0.1	0.8	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	0.4	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	1.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.3	GO:0044609	DBIRD complex(GO:0044609)
0.1	0.5	GO:1990037	Lewy body core(GO:1990037)
0.1	0.9	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.5	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.1	6.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	0.3	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1	0.9	GO:0031595	nuclear proteasome complex(GO:0031595)
0.1	5.4	GO:0031594	neuromuscular junction(GO:0031594)
0.1	3.7	GO:0008180	COP9 signalosome(GO:0008180)
0.1	0.8	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.7	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.8	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	1.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.2	GO:0000806	Y chromosome(GO:0000806)
0.0	0.5	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	3.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.9	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.5	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.7	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.0	3.7	GO:0005604	basement membrane(GO:0005604)
0.0	0.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.2	GO:1990584	cardiac Troponin complex(GO:1990584)
0.0	0.1	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	3.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	2.5	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.2	GO:0071439	clathrin complex(GO:0071439)
0.0	2.1	GO:0005882	intermediate filament(GO:0005882)
0.0	8.2	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.8	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.7	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	1.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0097512	cardiac myofibril(GO:0097512)
0.0	1.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	1.0	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0001741	XY body(GO:0001741)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	6.3	GO:0005925	focal adhesion(GO:0005925)
0.0	0.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.6	GO:0042641	actomyosin(GO:0042641)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0034364	high-density lipoprotein particle(GO:0034364)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.9	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.6	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.1	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
1.1	5.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.8	21.7	GO:0005523	tropomyosin binding(GO:0005523)
0.7	11.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6	1.9	GO:0070699	type II activin receptor binding(GO:0070699)
0.5	3.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4	4.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.4	1.3	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.4	1.5	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.4	1.4	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.3	1.4	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3	1.9	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.3	3.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2	0.7	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	1.6	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2	1.1	GO:0050436	microfibril binding(GO:0050436)
0.2	1.4	GO:0004882	androgen receptor activity(GO:0004882)
0.2	21.3	GO:0005518	collagen binding(GO:0005518)
0.2	3.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	0.6	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2	3.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.2	2.7	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	0.8	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2	0.6	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.2	0.5	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.2	0.9	GO:0031708	endothelin B receptor binding(GO:0031708)
0.2	1.8	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	0.7	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.1	0.7	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	0.7	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.8	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	13.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	3.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.9	GO:0017022	myosin binding(GO:0017022)
0.1	1.1	GO:0032190	acrosin binding(GO:0032190)
0.1	0.4	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.8	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1	0.3	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1	1.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	0.3	GO:0004958	prostaglandin F receptor activity(GO:0004958)
0.1	0.5	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.8	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.9	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.9	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	1.0	GO:0045159	myosin II binding(GO:0045159)
0.1	3.6	GO:0050699	WW domain binding(GO:0050699)
0.1	13.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	0.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.4	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	2.3	GO:0005109	frizzled binding(GO:0005109)
0.1	1.4	GO:0042166	acetylcholine binding(GO:0042166)
0.1	0.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.3	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.3	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1	0.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	1.6	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	2.2	GO:0003785	actin monomer binding(GO:0003785)
0.1	5.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.2	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	1.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	1.7	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.9	GO:0030275	LRR domain binding(GO:0030275)
0.0	1.7	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	1.1	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	5.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.0	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	1.6	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.6	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.7	GO:0008329	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.4	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.8	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.9	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.2	GO:0031014	troponin T binding(GO:0031014)
0.0	0.5	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.3	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.7	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	2.5	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.2	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.2	GO:0089720	caspase binding(GO:0089720)
0.0	0.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.5	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	1.6	GO:0002020	protease binding(GO:0002020)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.5	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.1	GO:0005543	phospholipid binding(GO:0005543)
0.0	0.5	GO:0042287	MHC protein binding(GO:0042287)
0.0	1.9	GO:0003924	GTPase activity(GO:0003924)
0.0	0.5	GO:0008233	peptidase activity(GO:0008233)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	GO:0035690	cellular response to drug(GO:0035690)
0.2	0.7	GO:0046098	guanine metabolic process(GO:0046098)
0.2	5.8	GO:0006825	copper ion transport(GO:0006825)
0.2	1.0	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	0.7	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.9	GO:0009082	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1	0.8	GO:0071233	cellular response to leucine(GO:0071233)
0.1	0.5	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.1	1.1	GO:0035799	ureter maturation(GO:0035799)
0.1	0.4	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1	0.3	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1	0.4	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.1	0.6	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.1	0.3	GO:0099543	retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1	0.3	GO:0007412	axon target recognition(GO:0007412)
0.1	0.3	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.4	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.6	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.5	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	0.4	GO:0061737	leukotriene signaling pathway(GO:0061737)
0.1	0.3	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1	0.2	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.1	0.2	GO:0060369	positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1	0.3	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	1.0	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1	0.2	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1	0.3	GO:0052199	negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1	0.4	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.2	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.1	0.2	GO:0001555	oocyte growth(GO:0001555)
0.0	0.2	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0	0.2	GO:0072658	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.1	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.0	0.3	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.2	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.3	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.3	GO:1990539	fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.2	GO:0006574	valine catabolic process(GO:0006574)
0.0	0.3	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.2	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.6	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0032672	response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0048213	Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0	0.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.3	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.0	0.5	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.3	GO:0072221	metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0	0.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0033625	positive regulation of integrin activation(GO:0033625)
0.0	0.2	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.2	GO:0000393	spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0	0.2	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.3	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.3	GO:0030263	resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
0.0	0.6	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.1	GO:0002101	tRNA wobble cytosine modification(GO:0002101)
0.0	0.1	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.1	GO:0051414	response to cortisol(GO:0051414)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0001554	luteolysis(GO:0001554)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.3	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.1	GO:0032900	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.3	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.5	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0	0.7	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.4	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.0	0.2	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.0	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0	0.1	GO:0006021	inositol biosynthetic process(GO:0006021)
0.0	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.2	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:0070129	regulation of mitochondrial translation(GO:0070129)
0.0	0.1	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.0	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.4	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.3	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.2	GO:1903817	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0	0.1	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.3	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.0	GO:1900158	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0	0.1	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.6	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0010578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0	0.1	GO:0001507	acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0030193	regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0	0.1	GO:0022405	hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405)
0.0	0.0	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.0	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0	0.1	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	2.7	GO:0065004	protein-DNA complex assembly(GO:0065004)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.2	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.8	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	1.0	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.7	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.2	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.6	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	1.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	6.1	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	0.9	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.6	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	1.6	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.3	GO:0004139	deoxyribose-phosphate aldolase activity(GO:0004139)
0.1	0.3	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.6	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	1.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	1.8	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.1	2.1	GO:0042605	peptide antigen binding(GO:0042605)
0.1	0.3	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.4	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0017130	poly(C) RNA binding(GO:0017130)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0	1.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.8	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0050429	calcium-dependent phospholipase C activity(GO:0050429)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.3	GO:0008392	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.3	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.6	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	0.1	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	0.3	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	2.0	GO:0003823	antigen binding(GO:0003823)
0.0	0.0	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.0	0.1	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.5	1.9	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	0.9	GO:1990423	RZZ complex(GO:1990423)
0.2	1.6	GO:0097452	GAIT complex(GO:0097452)
0.2	1.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	0.6	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.2	2.0	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	0.5	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	0.5	GO:0000799	nuclear condensin complex(GO:0000799)
0.1	1.5	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	1.0	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1	0.8	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	1.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	0.8	GO:0005955	calcineurin complex(GO:0005955)
0.1	1.0	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.5	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.4	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.2	GO:1990298	mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1	0.8	GO:0097255	R2TP complex(GO:0097255)
0.1	0.9	GO:0000243	commitment complex(GO:0000243)
0.1	0.8	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.4	GO:0097165	nuclear stress granule(GO:0097165)
0.1	0.4	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.2	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.4	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.3	GO:0060091	kinocilium(GO:0060091)
0.0	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.4	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.3	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.7	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	2.7	GO:0016459	myosin complex(GO:0016459)
0.0	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.6	GO:0071564	npBAF complex(GO:0071564)
0.0	0.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	1.2	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.2	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.4	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	3.6	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.2	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.2	GO:0030992	intraciliary transport particle B(GO:0030992)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	1.9	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	1.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.8	GO:0031093	platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:1990423	RZZ complex(GO:1990423)
0.1	0.3	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1	0.5	GO:0030870	Mre11 complex(GO:0030870)
0.1	0.9	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.3	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.3	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.5	GO:0016013	syntrophin complex(GO:0016013)
0.0	0.2	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.0	0.2	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.4	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.0	0.7	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.7	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.4	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0097255	R2TP complex(GO:0097255)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.4	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.5	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0	0.5	GO:0000145	exocyst(GO:0000145)
0.0	0.6	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.4	GO:0043194	axon initial segment(GO:0043194)
0.0	0.4	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	6.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	2.2	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	2.3	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	2.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.3	PID ATM PATHWAY	ATM pathway
0.0	0.5	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	2.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.6	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	1.0	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0032089	NACHT domain binding(GO:0032089)
0.6	1.9	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.4	1.3	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4	1.8	GO:0070026	nitric oxide binding(GO:0070026)
0.4	1.4	GO:0032038	myosin II heavy chain binding(GO:0032038)
0.3	0.9	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.2	2.5	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2	2.8	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	0.8	GO:0043515	kinetochore binding(GO:0043515)
0.2	2.0	GO:0032027	myosin light chain binding(GO:0032027)
0.2	1.5	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1	0.4	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.1	0.6	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.6	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1	0.4	GO:0016603	glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1	0.6	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.3	GO:0070283	lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.1	0.3	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.1	0.4	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.3	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1	0.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	1.6	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	0.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.5	GO:0043208	glycosphingolipid binding(GO:0043208)
0.1	0.5	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	0.3	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	0.2	GO:0102008	cytosolic dipeptidase activity(GO:0102008)
0.1	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.1	0.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	1.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0042610	CD8 receptor binding(GO:0042610)
0.0	0.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.0	0.4	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	1.0	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.5	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.8	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.5	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.4	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.2	GO:0031208	POZ domain binding(GO:0031208)
0.0	0.2	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	1.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	1.5	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	1.3	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.4	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.8	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.1	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0	0.5	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0	1.0	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.5	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0061714	folic acid receptor activity(GO:0061714)
0.0	0.3	GO:0008494	translation activator activity(GO:0008494)
0.0	0.2	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.8	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.3	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.4	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.5	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.8	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.0	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.6	1.9	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.5	2.9	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.2	1.4	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	1.6	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.6	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.9	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.6	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.4	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.2	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.3	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.9	GO:0030574	collagen catabolic process(GO:0030574)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	2.0	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.7	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
2.4	7.1	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.7	5.1	GO:0002514	B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
1.5	6.1	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.1	12.9	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.9	2.7	GO:1990523	bone regeneration(GO:1990523)
0.7	1.4	GO:1904397	negative regulation of neuromuscular junction development(GO:1904397)
0.6	3.2	GO:0097338	response to clozapine(GO:0097338)
0.6	4.4	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.6	1.9	GO:0060279	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.6	4.5	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5	1.4	GO:2000276	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.4	1.3	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.4	0.9	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.4	1.5	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.4	1.4	GO:0003409	optic cup structural organization(GO:0003409)
0.3	1.6	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3	2.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3	1.6	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.3	1.9	GO:2000334	lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3	3.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.3	0.8	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.3	1.8	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3	0.8	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2	11.0	GO:0010107	potassium ion import(GO:0010107)
0.2	3.7	GO:0000338	protein deneddylation(GO:0000338)
0.2	0.9	GO:0071386	cellular response to corticosterone stimulus(GO:0071386)
0.2	0.9	GO:0007525	somatic muscle development(GO:0007525)
0.2	3.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	2.4	GO:0009414	response to water deprivation(GO:0009414)
0.2	0.6	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2	2.6	GO:0070307	lens fiber cell development(GO:0070307)
0.2	2.8	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	1.0	GO:0030047	actin modification(GO:0030047)
0.2	0.4	GO:2000364	regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.2	1.3	GO:0097577	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2	1.1	GO:0035803	egg coat formation(GO:0035803)
0.2	0.9	GO:0070980	biphenyl catabolic process(GO:0070980)
0.2	1.3	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2	2.1	GO:0042118	endothelial cell activation(GO:0042118)
0.2	1.4	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.2	0.5	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	0.5	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2	0.5	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2	0.5	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2	0.8	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.2	1.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	1.3	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1	1.2	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.1	1.3	GO:0098712	L-glutamate import across plasma membrane(GO:0098712)
0.1	0.6	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.6	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.1	1.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.8	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	0.5	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.1	1.3	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	0.6	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	1.1	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1	0.4	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1	6.0	GO:0018149	peptide cross-linking(GO:0018149)
0.1	1.9	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.3	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.1	0.7	GO:0001701	in utero embryonic development(GO:0001701)
0.1	1.8	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.2	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
0.1	0.8	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.1	0.7	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1	3.7	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	2.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.5	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	0.3	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.3	GO:0035905	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1	0.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.8	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.1	6.4	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.1	GO:0090107	regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1	0.7	GO:0015705	iodide transport(GO:0015705)
0.1	0.7	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	0.7	GO:0030091	protein repair(GO:0030091)
0.1	0.8	GO:0090292	nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	1.8	GO:0007517	muscle organ development(GO:0007517)
0.1	0.3	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1	0.4	GO:0035881	amacrine cell differentiation(GO:0035881)
0.1	2.7	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.4	GO:0001781	neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.1	0.6	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.8	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.7	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.1	0.5	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.1	0.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	1.1	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	1.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.5	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	0.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.5	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.2	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.4	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.3	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.0	0.6	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.5	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.4	GO:0009441	glycolate metabolic process(GO:0009441)
0.0	0.4	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.1	GO:0035747	natural killer cell chemotaxis(GO:0035747) eosinophil chemotaxis(GO:0048245) regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	1.6	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.2	GO:0048478	replication fork protection(GO:0048478)
0.0	0.7	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.6	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0019442	tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	17.6	GO:0006936	muscle contraction(GO:0006936)
0.0	0.7	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.3	GO:0071798	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.3	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0	0.6	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.2	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.5	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	1.0	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.6	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.4	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.6	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.3	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.2	GO:0006848	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.3	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.3	GO:0070989	oxidative demethylation(GO:0070989)
0.0	2.1	GO:0070268	cornification(GO:0070268)
0.0	2.6	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0	0.5	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	1.8	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.2	GO:0032966	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252) keratinocyte migration(GO:0051546)
0.0	0.1	GO:1903751	positive regulation of NK T cell activation(GO:0051135) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	0.9	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.3	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.0	GO:0045726	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.0	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0	0.7	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	2.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	1.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.1	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.6	GO:1901998	toxin transport(GO:1901998)
0.0	0.8	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.5	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	1.4	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.3	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.2	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0002035	brain renin-angiotensin system(GO:0002035)
0.0	0.0	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0	0.3	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.5	GO:0046850	regulation of bone remodeling(GO:0046850)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0	0.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	2.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	1.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	1.0	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.3	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	1.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis