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ENCODE cell lines, expression (Ernst 2011)

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Results for HOXD11_HOXA11

Z-value: 0.76

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Transcription factors associated with HOXD11_HOXA11

Gene Symbol Gene ID Gene Info
HOXD11
ENSG00000128713.11 HOXD11
HOXA11
ENSG00000005073.5 HOXA11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD11hg19_v2_chr2_+_176972000_1769720250.572.2e-02Click!
HOXA11hg19_v2_chr7_-_27224795_27224840,
hg19_v2_chr7_-_27224842_27224872		0.332.1e-01Click!

Activity profile of HOXD11_HOXA11 motif

Sorted Z-values of HOXD11_HOXA11 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD11_HOXA11

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_+_65382433 2.20 ENST00000374727.3
 HEPH
 hephaestin
chrX_+_65384182 1.48 ENST00000441993.2
ENST00000419594.1
 HEPH
 hephaestin
chrX_+_65384052 1.30 ENST00000336279.5
ENST00000458621.1
 HEPH
 hephaestin
chr15_-_58571445 1.15 ENST00000558231.1
 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
chr19_-_10446449 1.06 ENST00000592439.1
 ICAM3
 intercellular adhesion molecule 3
chr12_-_25055177 0.88 ENST00000538118.1
 BCAT1
 branched chain amino-acid transaminase 1, cytosolic
chrX_+_65382381 0.83 ENST00000519389.1
 HEPH
 hephaestin
chr18_-_52989217 0.82 ENST00000570287.2
 TCF4
 transcription factor 4
chrX_+_30261847 0.72 ENST00000378981.3
ENST00000397550.1
 MAGEB1
 melanoma antigen family B, 1
chr7_+_150065278 0.70 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
 REPIN1
 replication initiator 1
chr17_+_58018269 0.63 ENST00000591035.1
 RP11-178C3.1
 Uncharacterized protein
chr6_+_12958137 0.62 ENST00000457702.2
ENST00000379345.2
 PHACTR1
 phosphatase and actin regulator 1
chr4_+_120056939 0.59 ENST00000307128.5
 MYOZ2
 myozenin 2
chr18_-_53069419 0.59 ENST00000570177.2
 TCF4
 transcription factor 4
chrX_-_100604184 0.58 ENST00000372902.3
 TIMM8A
 translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr3_-_141747950 0.56 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr12_-_71148357 0.56 ENST00000378778.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chrX_+_49294472 0.56 ENST00000361446.5
 GAGE12B
 G antigen 12B
chr18_-_53177984 0.55 ENST00000543082.1
 TCF4
 transcription factor 4
chr14_-_25479811 0.55 ENST00000550887.1
 STXBP6
 syntaxin binding protein 6 (amisyn)
chr8_+_107738240 0.55 ENST00000449762.2
ENST00000297447.6
 OXR1
 oxidation resistance 1
chr4_+_40198527 0.54 ENST00000381799.5
 RHOH
 ras homolog family member H
chr1_-_144995074 0.52 ENST00000534536.1
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr18_+_32556892 0.51 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
chr6_-_32498046 0.50 ENST00000374975.3
 HLA-DRB5
 major histocompatibility complex, class II, DR beta 5
chr5_-_111093167 0.50 ENST00000446294.2
ENST00000419114.2
 NREP
 neuronal regeneration related protein
chr2_+_109204743 0.49 ENST00000332345.6
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr19_+_1440838 0.48 ENST00000594262.1
 AC027307.3
 Uncharacterized protein
chr6_+_42584847 0.46 ENST00000372883.3
 UBR2
 ubiquitin protein ligase E3 component n-recognin 2
chr4_+_86396265 0.45 ENST00000395184.1
 ARHGAP24
 Rho GTPase activating protein 24
chr12_-_71148413 0.45 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr6_+_13272904 0.44 ENST00000379335.3
ENST00000379329.1
 PHACTR1
 phosphatase and actin regulator 1
chr1_-_160231451 0.44 ENST00000495887.1
 DCAF8
 DDB1 and CUL4 associated factor 8
chr6_+_26156551 0.43 ENST00000304218.3
 HIST1H1E
 histone cluster 1, H1e
chr21_+_35736302 0.43 ENST00000290310.3
 KCNE2
 potassium voltage-gated channel, Isk-related family, member 2
chr4_+_170581213 0.42 ENST00000507875.1
 CLCN3
 chloride channel, voltage-sensitive 3
chr3_+_15045419 0.42 ENST00000406272.2
 NR2C2
 nuclear receptor subfamily 2, group C, member 2
chr3_+_169629354 0.41 ENST00000428432.2
ENST00000335556.3
 SAMD7
 sterile alpha motif domain containing 7
chr16_+_20775358 0.41 ENST00000440284.2
 ACSM3
 acyl-CoA synthetase medium-chain family member 3
chr1_+_192544857 0.41 ENST00000367459.3
ENST00000469578.2
 RGS1
 regulator of G-protein signaling 1
chr3_+_157827841 0.40 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
 RSRC1
 arginine/serine-rich coiled-coil 1
chr1_-_155880672 0.40 ENST00000609492.1
ENST00000368322.3
 RIT1
 Ras-like without CAAX 1
chr15_+_66797455 0.39 ENST00000446801.2
 ZWILCH
 zwilch kinetochore protein
chr12_-_90049828 0.39 ENST00000261173.2
ENST00000348959.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr22_+_41956767 0.37 ENST00000306149.7
 CSDC2
 cold shock domain containing C2, RNA binding
chr2_+_109204909 0.37 ENST00000393310.1
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr11_-_5255861 0.37 ENST00000380299.3
 HBD
 hemoglobin, delta
chr5_+_53751445 0.37 ENST00000302005.1
 HSPB3
 heat shock 27kDa protein 3
chr19_-_36233332 0.37 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
 IGFLR1
 IGF-like family receptor 1
chr6_+_151042224 0.37 ENST00000358517.2
 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr10_+_94352956 0.37 ENST00000260731.3
 KIF11
 kinesin family member 11
chr18_-_52989525 0.37 ENST00000457482.3
 TCF4
 transcription factor 4
chrX_-_33229636 0.36 ENST00000357033.4
 DMD
 dystrophin
chr15_+_66797627 0.36 ENST00000565627.1
ENST00000564179.1
 ZWILCH
 zwilch kinetochore protein
chr12_-_90049878 0.35 ENST00000359142.3
 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
chr1_+_23345943 0.35 ENST00000400181.4
ENST00000542151.1
 KDM1A
 lysine (K)-specific demethylase 1A
chr1_+_23345930 0.35 ENST00000356634.3
 KDM1A
 lysine (K)-specific demethylase 1A
chr5_-_145562147 0.35 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
 LARS
 leucyl-tRNA synthetase
chr15_-_55541227 0.35 ENST00000566877.1
 RAB27A
 RAB27A, member RAS oncogene family
chr6_+_26199737 0.35 ENST00000359985.1
 HIST1H2BF
 histone cluster 1, H2bf
chr6_-_32157947 0.35 ENST00000375050.4
 PBX2
 pre-B-cell leukemia homeobox 2
chr15_+_67841330 0.35 ENST00000354498.5
 MAP2K5
 mitogen-activated protein kinase kinase 5
chr7_+_73106926 0.34 ENST00000453316.1
 WBSCR22
 Williams Beuren syndrome chromosome region 22
chr9_+_108463234 0.33 ENST00000374688.1
 TMEM38B
 transmembrane protein 38B
chr16_+_68119764 0.32 ENST00000570212.1
ENST00000562926.1
 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_157198860 0.32 ENST00000409572.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr1_+_183774240 0.32 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr12_-_9913489 0.31 ENST00000228434.3
ENST00000536709.1
 CD69
 CD69 molecule
chr6_-_26189304 0.31 ENST00000340756.2
 HIST1H4D
 histone cluster 1, H4d
chr10_-_115614127 0.30 ENST00000369305.1
 DCLRE1A
 DNA cross-link repair 1A
chr3_-_98241358 0.29 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
 CLDND1
 claudin domain containing 1
chr8_-_90996459 0.29 ENST00000517337.1
ENST00000409330.1
 NBN
 nibrin
chr3_+_173116225 0.29 ENST00000457714.1
 NLGN1
 neuroligin 1
chr4_+_41258786 0.29 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
 UCHL1
 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr17_-_46690839 0.28 ENST00000498634.2
 HOXB8
 homeobox B8
chrX_-_55057403 0.28 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
 ALAS2
 aminolevulinate, delta-, synthase 2
chr1_-_68962805 0.28 ENST00000370966.5
 DEPDC1
 DEP domain containing 1
chr19_-_54618650 0.28 ENST00000391757.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr12_-_6233828 0.28 ENST00000572068.1
ENST00000261405.5
 VWF
 von Willebrand factor
chr2_+_109271481 0.28 ENST00000542845.1
ENST00000393314.2
 LIMS1
 LIM and senescent cell antigen-like domains 1
chr7_+_138145076 0.28 ENST00000343526.4
 TRIM24
 tripartite motif containing 24
chr7_-_37026108 0.27 ENST00000396045.3
 ELMO1
 engulfment and cell motility 1
chr3_+_157154578 0.27 ENST00000295927.3
 PTX3
 pentraxin 3, long
chr1_+_6640108 0.27 ENST00000377674.4
ENST00000488936.1
 ZBTB48
 zinc finger and BTB domain containing 48
chr14_-_21493123 0.27 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
 NDRG2
 NDRG family member 2
chr8_-_91095099 0.27 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr6_-_25042231 0.27 ENST00000510784.2
 FAM65B
 family with sequence similarity 65, member B
chr1_+_227127981 0.27 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
 ADCK3
 aarF domain containing kinase 3
chr1_+_150898812 0.27 ENST00000271640.5
ENST00000448029.1
ENST00000368962.2
ENST00000534805.1
ENST00000368969.4
ENST00000368963.1
ENST00000498193.1
 SETDB1
 SET domain, bifurcated 1
chr8_+_77593448 0.27 ENST00000521891.2
 ZFHX4
 zinc finger homeobox 4
chr21_-_28338732 0.27 ENST00000284987.5
 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr4_-_84035868 0.26 ENST00000426923.2
ENST00000509973.1
 PLAC8
 placenta-specific 8
chr17_-_38545799 0.26 ENST00000577541.1
 TOP2A
 topoisomerase (DNA) II alpha 170kDa
chr19_+_54619125 0.26 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
 PRPF31
 pre-mRNA processing factor 31
chrX_-_135962876 0.26 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
 RBMX
 RNA binding motif protein, X-linked
chr8_-_95220775 0.26 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
 CDH17
 cadherin 17, LI cadherin (liver-intestine)
chr6_+_108487245 0.26 ENST00000368986.4
 NR2E1
 nuclear receptor subfamily 2, group E, member 1
chr1_-_27961720 0.26 ENST00000545953.1
ENST00000374005.3
 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
chr2_-_207023918 0.26 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
 NDUFS1
 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr12_+_25205568 0.25 ENST00000548766.1
ENST00000556887.1
 LRMP
 lymphoid-restricted membrane protein
chr4_-_84035905 0.25 ENST00000311507.4
 PLAC8
 placenta-specific 8
chr9_-_26892765 0.25 ENST00000520187.1
ENST00000333916.5
 CAAP1
 caspase activity and apoptosis inhibitor 1
chr15_-_55563072 0.25 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
 RAB27A
 RAB27A, member RAS oncogene family
chr6_-_111804905 0.25 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr10_+_21823079 0.24 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
 MLLT10
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr8_-_90996837 0.24 ENST00000519426.1
ENST00000265433.3
 NBN
 nibrin
chr1_+_62439037 0.24 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr2_-_176046391 0.24 ENST00000392541.3
ENST00000409194.1
 ATP5G3
 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chrX_-_101771645 0.24 ENST00000289373.4
 TMSB15A
 thymosin beta 15a
chr4_+_174089904 0.24 ENST00000265000.4
 GALNT7
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_-_144995002 0.24 ENST00000369356.4
 PDE4DIP
 phosphodiesterase 4D interacting protein
chr3_+_190105909 0.24 ENST00000456423.1
 CLDN16
 claudin 16
chr18_-_5396271 0.24 ENST00000579951.1
 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
chr10_+_35456444 0.24 ENST00000361599.4
 CREM
 cAMP responsive element modulator
chr1_-_25291475 0.23 ENST00000338888.3
ENST00000399916.1
 RUNX3
 runt-related transcription factor 3
chr2_-_136678123 0.23 ENST00000422708.1
 DARS
 aspartyl-tRNA synthetase
chr10_+_88428206 0.23 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
 LDB3
 LIM domain binding 3
chr22_+_23248512 0.23 ENST00000390325.2
 IGLC3
 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr15_+_35270552 0.22 ENST00000391457.2
 AC114546.1
 HCG37415; PRO1914; Uncharacterized protein
chr19_-_10420459 0.22 ENST00000403352.1
ENST00000403903.3
 ZGLP1
 zinc finger, GATA-like protein 1
chr12_+_51318513 0.22 ENST00000332160.4
 METTL7A
 methyltransferase like 7A
chr9_+_2029019 0.22 ENST00000382194.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_26798955 0.22 ENST00000361427.5
 HMGN2
 high mobility group nucleosomal binding domain 2
chr9_+_131549610 0.22 ENST00000223865.8
 TBC1D13
 TBC1 domain family, member 13
chr5_-_79950775 0.21 ENST00000439211.2
 DHFR
 dihydrofolate reductase
chr12_+_25205666 0.21 ENST00000547044.1
 LRMP
 lymphoid-restricted membrane protein
chr12_+_52056548 0.21 ENST00000545061.1
ENST00000355133.3
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr7_-_38394118 0.21 ENST00000390345.2
 TRGV4
 T cell receptor gamma variable 4
chr9_+_106856831 0.21 ENST00000303219.8
ENST00000374787.3
 SMC2
 structural maintenance of chromosomes 2
chr12_-_49418407 0.21 ENST00000526209.1
 KMT2D
 lysine (K)-specific methyltransferase 2D
chr5_-_111093759 0.21 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
 NREP
 neuronal regeneration related protein
chr6_+_42847348 0.20 ENST00000493763.1
ENST00000304734.5
 RPL7L1
 ribosomal protein L7-like 1
chr6_-_166582107 0.20 ENST00000296946.2
ENST00000461348.2
ENST00000366871.3
 T
 T, brachyury homolog (mouse)
chr5_-_98262240 0.20 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chr1_-_28527152 0.20 ENST00000321830.5
 AL353354.1
 Uncharacterized protein
chr18_-_67624160 0.20 ENST00000581982.1
ENST00000280200.4
 CD226
 CD226 molecule
chr12_-_49504655 0.20 ENST00000551782.1
ENST00000267102.8
 LMBR1L
 limb development membrane protein 1-like
chr2_-_169887827 0.20 ENST00000263817.6
 ABCB11
 ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr1_+_70876926 0.20 ENST00000370938.3
ENST00000346806.2
 CTH
 cystathionase (cystathionine gamma-lyase)
chr11_-_47447970 0.20 ENST00000298852.3
ENST00000530912.1
 PSMC3
 proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr15_-_35047166 0.20 ENST00000290374.4
 GJD2
 gap junction protein, delta 2, 36kDa
chr2_-_191115229 0.19 ENST00000409820.2
ENST00000410045.1
 HIBCH
 3-hydroxyisobutyryl-CoA hydrolase
chr12_-_49504623 0.19 ENST00000550137.1
ENST00000547382.1
 LMBR1L
 limb development membrane protein 1-like
chr12_-_100486668 0.19 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
 UHRF1BP1L
 UHRF1 binding protein 1-like
chr8_+_1993173 0.19 ENST00000523438.1
 MYOM2
 myomesin 2
chr2_+_90198535 0.19 ENST00000390276.2
 IGKV1D-12
 immunoglobulin kappa variable 1D-12
chr12_-_47219733 0.19 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
 SLC38A4
 solute carrier family 38, member 4
chr4_+_95376396 0.19 ENST00000508216.1
ENST00000514743.1
 PDLIM5
 PDZ and LIM domain 5
chrX_+_99899180 0.19 ENST00000373004.3
 SRPX2
 sushi-repeat containing protein, X-linked 2
chr8_+_21823726 0.19 ENST00000433566.4
 XPO7
 exportin 7
chr3_+_35722487 0.19 ENST00000441454.1
 ARPP21
 cAMP-regulated phosphoprotein, 21kDa
chr4_-_76957214 0.19 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chr6_+_44215603 0.18 ENST00000371554.1
 HSP90AB1
 heat shock protein 90kDa alpha (cytosolic), class B member 1
chr13_-_47012325 0.18 ENST00000409879.2
 KIAA0226L
 KIAA0226-like
chr15_-_80263506 0.18 ENST00000335661.6
 BCL2A1
 BCL2-related protein A1
chr8_-_117886955 0.18 ENST00000297338.2
 RAD21
 RAD21 homolog (S. pombe)
chr15_+_41549105 0.18 ENST00000560965.1
 CHP1
 calcineurin-like EF-hand protein 1
chr8_+_1993152 0.18 ENST00000262113.4
 MYOM2
 myomesin 2
chr11_+_128563652 0.17 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr11_-_102576537 0.17 ENST00000260229.4
 MMP27
 matrix metallopeptidase 27
chr17_+_7155819 0.17 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
 ELP5
 elongator acetyltransferase complex subunit 5
chr12_-_56236734 0.17 ENST00000548629.1
 MMP19
 matrix metallopeptidase 19
chr3_-_164796269 0.17 ENST00000264382.3
 SI
 sucrase-isomaltase (alpha-glucosidase)
chr10_-_98031265 0.17 ENST00000224337.5
ENST00000371176.2
 BLNK
 B-cell linker
chr14_-_106926724 0.17 ENST00000434710.1
 IGHV3-43
 immunoglobulin heavy variable 3-43
chr1_+_65730385 0.17 ENST00000263441.7
ENST00000395325.3
 DNAJC6
 DnaJ (Hsp40) homolog, subfamily C, member 6
chr22_-_50700140 0.17 ENST00000215659.8
 MAPK12
 mitogen-activated protein kinase 12
chrX_+_78003204 0.17 ENST00000435339.3
ENST00000514744.1
 LPAR4
 lysophosphatidic acid receptor 4
chr3_+_155838337 0.17 ENST00000490337.1
ENST00000389636.5
 KCNAB1
 potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr8_+_94241867 0.17 ENST00000598428.1
 AC016885.1
 Uncharacterized protein
chr11_-_47447767 0.17 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
 PSMC3
 proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr11_-_62473706 0.16 ENST00000403550.1
 BSCL2
 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr3_+_157828152 0.16 ENST00000476899.1
 RSRC1
 arginine/serine-rich coiled-coil 1
chr17_-_47755436 0.16 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
 SPOP
 speckle-type POZ protein
chr6_-_27114577 0.16 ENST00000356950.1
ENST00000396891.4
 HIST1H2BK
 histone cluster 1, H2bk
chr11_-_60674037 0.16 ENST00000541371.1
ENST00000227524.4
 PRPF19
 pre-mRNA processing factor 19
chr18_+_21032781 0.16 ENST00000339486.3
 RIOK3
 RIO kinase 3
chr14_-_21492113 0.16 ENST00000554094.1
 NDRG2
 NDRG family member 2
chr11_+_64001962 0.16 ENST00000309422.2
 VEGFB
 vascular endothelial growth factor B
chr19_-_50083822 0.16 ENST00000596358.1
 NOSIP
 nitric oxide synthase interacting protein
chr11_-_3400442 0.16 ENST00000429541.2
ENST00000532539.1
 ZNF195
 zinc finger protein 195
chr1_-_9129598 0.16 ENST00000535586.1
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_3400330 0.16 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
 ZNF195
 zinc finger protein 195
chr1_-_246357029 0.15 ENST00000391836.2
 SMYD3
 SET and MYND domain containing 3
chr19_-_54619006 0.15 ENST00000391759.1
 TFPT
 TCF3 (E2A) fusion partner (in childhood Leukemia)
chr15_+_93749295 0.15 ENST00000599897.1
 AC112693.2
 AC112693.2
chr8_+_125486939 0.15 ENST00000303545.3
 RNF139
 ring finger protein 139
chr6_-_116447283 0.15 ENST00000452729.1
ENST00000243222.4
 COL10A1
 collagen, type X, alpha 1
chr8_+_76452097 0.15 ENST00000396423.2
 HNF4G
 hepatocyte nuclear factor 4, gamma
chr2_+_68592305 0.15 ENST00000234313.7
 PLEK
 pleckstrin
chr11_-_62473776 0.15 ENST00000278893.7
ENST00000407022.3
ENST00000421906.1
 BSCL2
 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr9_-_93405352 0.15 ENST00000375765.3
 DIRAS2
 DIRAS family, GTP-binding RAS-like 2
chr19_-_50083803 0.15 ENST00000391853.3
ENST00000339093.3
 NOSIP
 nitric oxide synthase interacting protein
chr8_-_29120580 0.14 ENST00000524189.1
 KIF13B
 kinesin family member 13B
chr19_+_50084561 0.14 ENST00000246794.5
 PRRG2
 proline rich Gla (G-carboxyglutamic acid) 2
chrX_+_1455478 0.14 ENST00000331035.4
 IL3RA
 interleukin 3 receptor, alpha (low affinity)
chr1_-_9129631 0.14 ENST00000377414.3
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_23941680 0.14 ENST00000402377.3
 ZNF681
 zinc finger protein 681
chr15_-_22448819 0.14 ENST00000604066.1
 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr14_-_51027838 0.14 ENST00000555216.1
 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.2 2.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:0004819 glutamine-tRNA ligase activity(GO:0004819) valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0051870 methotrexate binding(GO:0051870)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 GO:0035690 cellular response to drug(GO:0035690)
0.2 0.7 GO:0046098 guanine metabolic process(GO:0046098)
0.2 5.8 GO:0006825 copper ion transport(GO:0006825)
0.2 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.9 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.8 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 1.1 GO:0035799 ureter maturation(GO:0035799)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.4 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.2 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.3 GO:1990539 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0032672 response to molecule of fungal origin(GO:0002238) regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0072221 metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0030263 resolution of meiotic recombination intermediates(GO:0000712) apoptotic chromosome condensation(GO:0030263)
0.0 0.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0001554 luteolysis(GO:0001554)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0032900 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.1 GO:0022405 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405)
0.0 0.0 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 2.7 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990423 RZZ complex(GO:1990423)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 6.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 2.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation