ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
HSF4 Links Ensembl NCBI GeneCards UniProt	ENSG00000102878.11	HSF4

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HSF4	hg19_v2_chr16_+_67198683_67198715	-0.16	5.5e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr11_-_122933043	3.51	ENST00000534624.1 ENST00000453788.2 ENST00000527387.1	HSPA8	heat shock 70kDa protein 8
chr11_-_122932730	3.49	ENST00000532182.1 ENST00000524590.1 ENST00000528292.1 ENST00000533540.1 ENST00000525463.1	HSPA8	heat shock 70kDa protein 8
chr11_-_111781610	2.62	ENST00000525823.1	CRYAB	crystallin, alpha B
chr11_-_111781454	2.49	ENST00000533280.1	CRYAB	crystallin, alpha B
chr7_-_56119156	2.40	ENST00000421312.1 ENST00000416592.1	PSPH	phosphoserine phosphatase
chr11_+_63953691	2.32	ENST00000543847.1	STIP1	stress-induced-phosphoprotein 1
chr7_-_56118981	2.20	ENST00000419984.2 ENST00000413218.1 ENST00000424596.1	PSPH	phosphoserine phosphatase
chr11_-_111794446	2.19	ENST00000527950.1	CRYAB	crystallin, alpha B
chr11_-_111782696	2.11	ENST00000227251.3 ENST00000526180.1	CRYAB	crystallin, alpha B
chr9_-_88715044	2.04	ENST00000388711.3 ENST00000466178.1	GOLM1	golgi membrane protein 1
chr11_-_111781554	1.94	ENST00000526167.1 ENST00000528961.1	CRYAB	crystallin, alpha B
chr11_+_63953587	1.86	ENST00000305218.4 ENST00000538945.1	STIP1	stress-induced-phosphoprotein 1
chr15_-_58357932	1.85	ENST00000347587.3	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr6_-_41909191	1.85	ENST00000512426.1 ENST00000372987.4	CCND3	cyclin D3
chr14_-_52535712	1.81	ENST00000216286.5 ENST00000541773.1	NID2	nidogen 2 (osteonidogen)
chr9_-_88714421	1.73	ENST00000388712.3	GOLM1	golgi membrane protein 1
chr6_-_41909561	1.68	ENST00000372991.4	CCND3	cyclin D3
chr14_-_23388338	1.67	ENST00000555209.1 ENST00000554256.1 ENST00000557403.1 ENST00000557549.1 ENST00000555676.1 ENST00000557571.1 ENST00000557464.1 ENST00000554618.1 ENST00000556862.1 ENST00000555722.1 ENST00000346528.5 ENST00000542016.2 ENST00000399922.2 ENST00000557227.1 ENST00000359890.3	RBM23	RNA binding motif protein 23
chr6_-_41909466	1.61	ENST00000414200.2	CCND3	cyclin D3
chr11_+_86013253	1.39	ENST00000533986.1 ENST00000278483.3	C11orf73	chromosome 11 open reading frame 73
chr11_-_111782484	1.37	ENST00000533971.1	CRYAB	crystallin, alpha B
chr3_+_138066539	1.32	ENST00000289104.4	MRAS	muscle RAS oncogene homolog
chr7_+_157129660	1.28	ENST00000429029.2 ENST00000262177.4 ENST00000417758.1 ENST00000452797.2 ENST00000443280.1	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6
chr3_+_158787041	1.26	ENST00000471575.1 ENST00000476809.1 ENST00000485419.1	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough
chr15_-_58357866	1.25	ENST00000537372.1	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr20_+_19867150	1.20	ENST00000255006.6	RIN2	Ras and Rab interactor 2
chr7_+_75931861	1.14	ENST00000248553.6	HSPB1	heat shock 27kDa protein 1
chr15_+_96869165	1.06	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr11_+_75273101	0.99	ENST00000533603.1 ENST00000358171.3 ENST00000526242.1	SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr11_+_20385327	0.98	ENST00000451739.2 ENST00000532505.1	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr6_-_106773291	0.97	ENST00000343245.3	ATG5	autophagy related 5
chr11_+_20385231	0.95	ENST00000530266.1 ENST00000421577.2 ENST00000443524.2 ENST00000419348.2	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr11_+_111782934	0.93	ENST00000304298.3	HSPB2	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_+_75273246	0.92	ENST00000526397.1 ENST00000529643.1 ENST00000525492.1 ENST00000530284.1 ENST00000532356.1 ENST00000524558.1	SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr2_+_85766280	0.92	ENST00000306434.3	MAT2A	methionine adenosyltransferase II, alpha
chr19_+_859425	0.88	ENST00000327726.6	CFD	complement factor D (adipsin)
chr19_+_859654	0.88	ENST00000592860.1	CFD	complement factor D (adipsin)
chr13_-_31736027	0.82	ENST00000380406.5 ENST00000320027.5 ENST00000380405.4	HSPH1	heat shock 105kDa/110kDa protein 1
chr13_-_31736132	0.82	ENST00000429785.2	HSPH1	heat shock 105kDa/110kDa protein 1
chr9_+_33025209	0.82	ENST00000330899.4 ENST00000544625.1	DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr3_-_185655795	0.81	ENST00000342294.4 ENST00000382191.4 ENST00000453386.2	TRA2B	transformer 2 beta homolog (Drosophila)
chr17_-_39928106	0.80	ENST00000540235.1	JUP	junction plakoglobin
chr1_-_6453426	0.75	ENST00000545482.1	ACOT7	acyl-CoA thioesterase 7
chr13_-_31736478	0.67	ENST00000445273.2	HSPH1	heat shock 105kDa/110kDa protein 1
chr3_-_195603566	0.66	ENST00000424563.1 ENST00000411741.1	TNK2	tyrosine kinase, non-receptor, 2
chr1_+_154947148	0.65	ENST00000368436.1 ENST00000308987.5	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr20_+_4666882	0.64	ENST00000379440.4 ENST00000430350.2	PRNP	prion protein
chr1_+_154947126	0.63	ENST00000368439.1	CKS1B	CDC28 protein kinase regulatory subunit 1B
chr15_+_79165222	0.62	ENST00000559930.1	MORF4L1	mortality factor 4 like 1
chr15_+_85359911	0.60	ENST00000258888.5	ALPK3	alpha-kinase 3
chr1_-_6453399	0.60	ENST00000608083.1	ACOT7	acyl-CoA thioesterase 7
chr9_-_6015607	0.58	ENST00000259569.5	RANBP6	RAN binding protein 6
chr3_-_183735731	0.58	ENST00000334444.6	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr21_-_40720974	0.57	ENST00000380748.1	HMGN1	high mobility group nucleosome binding domain 1
chr11_+_66512089	0.55	ENST00000524551.1 ENST00000525908.1 ENST00000360962.4 ENST00000346672.4 ENST00000527634.1 ENST00000540737.1	C11orf80	chromosome 11 open reading frame 80
chr11_+_66512303	0.54	ENST00000532565.2	C11orf80	chromosome 11 open reading frame 80
chr19_-_14629224	0.53	ENST00000254322.2	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr19_-_14628645	0.51	ENST00000598235.1	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr12_-_108154925	0.48	ENST00000228437.5	PRDM4	PR domain containing 4
chr9_-_13279406	0.48	ENST00000546205.1	MPDZ	multiple PDZ domain protein
chr4_-_25865159	0.48	ENST00000502949.1 ENST00000264868.5 ENST00000513691.1 ENST00000514872.1	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr7_+_56119323	0.45	ENST00000275603.4 ENST00000335503.3 ENST00000540286.1	CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)
chr5_+_10250328	0.44	ENST00000515390.1	CCT5	chaperonin containing TCP1, subunit 5 (epsilon)
chr4_-_159644507	0.44	ENST00000307720.3	PPID	peptidylprolyl isomerase D
chr11_+_20385666	0.43	ENST00000532081.1 ENST00000531058.1	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr17_-_62308087	0.42	ENST00000583097.1	TEX2	testis expressed 2
chr21_-_40720995	0.42	ENST00000380749.5	HMGN1	high mobility group nucleosome binding domain 1
chr11_-_82997013	0.42	ENST00000529073.1 ENST00000529611.1	CCDC90B	coiled-coil domain containing 90B
chr1_-_26232522	0.40	ENST00000399728.1	STMN1	stathmin 1
chr19_+_2269485	0.39	ENST00000582888.4 ENST00000602676.2 ENST00000322297.4 ENST00000583542.4	OAZ1	ornithine decarboxylase antizyme 1
chr7_-_26240357	0.39	ENST00000354667.4 ENST00000356674.7	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr1_+_27248203	0.37	ENST00000321265.5	NUDC	nudC nuclear distribution protein
chr11_-_82997371	0.37	ENST00000525503.1	CCDC90B	coiled-coil domain containing 90B
chr11_-_82997420	0.36	ENST00000455220.2 ENST00000529689.1	CCDC90B	coiled-coil domain containing 90B
chr17_+_1936687	0.36	ENST00000570477.1	DPH1	diphthamide biosynthesis 1
chrX_-_102943022	0.36	ENST00000433176.2	MORF4L2	mortality factor 4 like 2
chrX_-_102942961	0.35	ENST00000434230.1 ENST00000418819.1 ENST00000360458.1	MORF4L2	mortality factor 4 like 2
chrX_-_152989531	0.33	ENST00000458587.2 ENST00000416815.1	BCAP31	B-cell receptor-associated protein 31
chr3_+_101443476	0.32	ENST00000327230.4 ENST00000494050.1	CEP97	centrosomal protein 97kDa
chrX_-_152989798	0.32	ENST00000441714.1 ENST00000442093.1 ENST00000429550.1 ENST00000345046.6	BCAP31	B-cell receptor-associated protein 31
chr1_-_242162375	0.31	ENST00000357246.3	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma
chr1_-_45987526	0.29	ENST00000372079.1 ENST00000262746.1 ENST00000447184.1 ENST00000319248.8	PRDX1	peroxiredoxin 1
chr21_+_44394620	0.29	ENST00000291547.5	PKNOX1	PBX/knotted 1 homeobox 1
chr1_-_228613026	0.29	ENST00000366696.1	HIST3H3	histone cluster 3, H3
chr11_-_47870091	0.28	ENST00000526870.1	NUP160	nucleoporin 160kDa
chr11_+_45825896	0.27	ENST00000314134.3	SLC35C1	solute carrier family 35 (GDP-fucose transporter), member C1
chr12_-_110883346	0.27	ENST00000547365.1	ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr14_-_61124977	0.27	ENST00000554986.1	SIX1	SIX homeobox 1
chr1_+_144811744	0.27	ENST00000338347.4 ENST00000440491.2 ENST00000375552.4	NBPF9	neuroblastoma breakpoint family, member 9
chr10_-_62332357	0.27	ENST00000503366.1	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_102553371	0.25	ENST00000553585.1 ENST00000216281.8	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr8_+_143915663	0.25	ENST00000522728.1	GML	glycosylphosphatidylinositol anchored molecule like
chr15_+_44092784	0.25	ENST00000458412.1	HYPK	huntingtin interacting protein K
chr14_-_68141535	0.25	ENST00000554659.1	VTI1B	vesicle transport through interaction with t-SNAREs 1B
chr7_+_26240776	0.25	ENST00000337620.4	CBX3	chromobox homolog 3
chr11_-_134123142	0.23	ENST00000392595.2 ENST00000341541.3 ENST00000352327.5 ENST00000392594.3	THYN1	thymocyte nuclear protein 1
chr19_+_751122	0.23	ENST00000215582.6	MISP	mitotic spindle positioning
chr4_+_41258786	0.22	ENST00000503431.1 ENST00000284440.4 ENST00000508768.1 ENST00000512788.1	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr19_-_17958832	0.22	ENST00000458235.1	JAK3	Janus kinase 3
chr3_-_126327398	0.21	ENST00000383572.2	TXNRD3NB	thioredoxin reductase 3 neighbor
chr21_+_44394742	0.21	ENST00000432907.2	PKNOX1	PBX/knotted 1 homeobox 1
chr6_+_4890226	0.20	ENST00000343762.5	CDYL	chromodomain protein, Y-like
chr11_+_65770227	0.20	ENST00000527348.1	BANF1	barrier to autointegration factor 1
chr12_-_125401885	0.20	ENST00000542416.1	UBC	ubiquitin C
chr20_-_60573188	0.20	ENST00000474089.1	TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr1_+_196743912	0.19	ENST00000367425.4	CFHR3	complement factor H-related 3
chr5_+_446253	0.19	ENST00000315013.5	EXOC3	exocyst complex component 3
chr19_+_41509851	0.19	ENST00000593831.1 ENST00000330446.5	CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr16_+_28875126	0.18	ENST00000359285.5 ENST00000538342.1	SH2B1	SH2B adaptor protein 1
chr2_-_62115659	0.18	ENST00000544185.1	CCT4	chaperonin containing TCP1, subunit 4 (delta)
chr10_-_115423792	0.18	ENST00000369360.3 ENST00000360478.3 ENST00000359988.3 ENST00000369358.4	NRAP	nebulin-related anchoring protein
chr11_-_89956227	0.18	ENST00000457199.2 ENST00000530765.1	CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1
chrX_+_54947229	0.17	ENST00000442098.1 ENST00000430420.1 ENST00000453081.1 ENST00000173898.7 ENST00000319167.8 ENST00000375022.4 ENST00000399736.1 ENST00000440072.1 ENST00000420798.2 ENST00000431115.1 ENST00000440759.1 ENST00000375041.2	TRO	trophinin
chr13_-_31191642	0.17	ENST00000405805.1	HMGB1	high mobility group box 1
chr9_+_123970052	0.17	ENST00000373823.3	GSN	gelsolin
chr7_-_139763521	0.17	ENST00000263549.3	PARP12	poly (ADP-ribose) polymerase family, member 12
chr1_-_156308018	0.16	ENST00000496684.2 ENST00000368259.2 ENST00000368261.3 ENST00000472765.2 ENST00000533194.1 ENST00000478640.2	CCT3	chaperonin containing TCP1, subunit 3 (gamma)
chr11_-_108408895	0.16	ENST00000443411.1 ENST00000533052.1	EXPH5	exophilin 5
chr4_+_5526883	0.16	ENST00000195455.2	C4orf6	chromosome 4 open reading frame 6
chr11_-_89956461	0.16	ENST00000320585.6	CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1
chr12_+_103981044	0.15	ENST00000388887.2	STAB2	stabilin 2
chr14_+_96722539	0.15	ENST00000553356.1	BDKRB1	bradykinin receptor B1
chr2_-_62115725	0.15	ENST00000538252.1 ENST00000544079.1 ENST00000394440.3	CCT4	chaperonin containing TCP1, subunit 4 (delta)
chr12_+_2904102	0.15	ENST00000001008.4	FKBP4	FK506 binding protein 4, 59kDa
chr15_+_79165112	0.15	ENST00000426013.2	MORF4L1	mortality factor 4 like 1
chr11_+_65769946	0.14	ENST00000533166.1	BANF1	barrier to autointegration factor 1
chr20_-_23731893	0.14	ENST00000398402.1	CST1	cystatin SN
chr1_+_196857144	0.14	ENST00000367416.2 ENST00000251424.4 ENST00000367418.2	CFHR4	complement factor H-related 4
chr8_+_140943416	0.14	ENST00000507535.3	C8orf17	chromosome 8 open reading frame 17
chr18_+_11751493	0.13	ENST00000269162.5	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_+_12227035	0.13	ENST00000376259.3 ENST00000536782.1	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr1_-_146054494	0.12	ENST00000401009.2	NBPF11	neuroblastoma breakpoint family, member 11
chr15_+_79165151	0.12	ENST00000331268.5	MORF4L1	mortality factor 4 like 1
chrX_-_106243451	0.12	ENST00000355610.4 ENST00000535534.1	MORC4	MORC family CW-type zinc finger 4
chr8_-_89339705	0.12	ENST00000286614.6	MMP16	matrix metallopeptidase 16 (membrane-inserted)
chr1_-_53704157	0.10	ENST00000371466.4 ENST00000371470.3	MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)
chr9_-_137809718	0.10	ENST00000371806.3	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chr21_-_30445886	0.10	ENST00000431234.1 ENST00000540844.1 ENST00000286788.4	CCT8	chaperonin containing TCP1, subunit 8 (theta)
chr2_-_100759037	0.10	ENST00000317233.4 ENST00000423966.1 ENST00000416492.1	AFF3	AF4/FMR2 family, member 3
chr11_+_65769550	0.09	ENST00000312175.2 ENST00000445560.2 ENST00000530204.1	BANF1	barrier to autointegration factor 1
chr15_-_86338134	0.09	ENST00000337975.5	KLHL25	kelch-like family member 25
chr19_+_6135646	0.08	ENST00000588304.1 ENST00000588485.1 ENST00000588722.1 ENST00000591403.1 ENST00000586696.1 ENST00000589401.1 ENST00000252669.5	ACSBG2	acyl-CoA synthetase bubblegum family member 2
chr22_-_32334403	0.08	ENST00000543051.1	C22orf24	chromosome 22 open reading frame 24
chr20_-_23807358	0.08	ENST00000304725.2	CST2	cystatin SA
chr2_-_69664586	0.08	ENST00000303698.3 ENST00000394305.1 ENST00000410022.2	NFU1	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr11_+_65154070	0.07	ENST00000317568.5 ENST00000531296.1 ENST00000533782.1 ENST00000355991.5 ENST00000416776.2 ENST00000526201.1	FRMD8	FERM domain containing 8
chr2_-_208994548	0.07	ENST00000282141.3	CRYGC	crystallin, gamma C
chr9_+_34989638	0.07	ENST00000453597.3 ENST00000335998.3 ENST00000312316.5	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr14_-_23540826	0.07	ENST00000357481.2	ACIN1	apoptotic chromatin condensation inducer 1
chr20_-_43589109	0.07	ENST00000372813.3	TOMM34	translocase of outer mitochondrial membrane 34
chr19_-_17958771	0.06	ENST00000534444.1	JAK3	Janus kinase 3
chr5_+_140602904	0.06	ENST00000515856.2 ENST00000239449.4	PCDHB14	protocadherin beta 14
chrX_-_154563889	0.06	ENST00000369449.2 ENST00000321926.4	CLIC2	chloride intracellular channel 2
chr12_-_4754339	0.05	ENST00000228850.1	AKAP3	A kinase (PRKA) anchor protein 3
chr4_+_5527117	0.05	ENST00000505296.1	C4orf6	chromosome 4 open reading frame 6
chr9_-_86593238	0.05	ENST00000351839.3	HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr7_+_130020180	0.05	ENST00000481342.1 ENST00000011292.3 ENST00000604896.1	CPA1	carboxypeptidase A1 (pancreatic)
chr5_+_133706865	0.04	ENST00000265339.2	UBE2B	ubiquitin-conjugating enzyme E2B
chr14_-_23540747	0.04	ENST00000555566.1 ENST00000338631.6 ENST00000557515.1 ENST00000397341.3	ACIN1	apoptotic chromatin condensation inducer 1
chr15_-_86338100	0.04	ENST00000536947.1	KLHL25	kelch-like family member 25
chr5_+_133707252	0.04	ENST00000506787.1 ENST00000507277.1	UBE2B	ubiquitin-conjugating enzyme E2B
chr7_+_130020932	0.03	ENST00000484324.1	CPA1	carboxypeptidase A1 (pancreatic)
chr6_-_32339649	0.03	ENST00000527965.1 ENST00000532023.1 ENST00000447241.2 ENST00000375007.4 ENST00000534588.1	C6orf10	chromosome 6 open reading frame 10
chr6_-_32339671	0.03	ENST00000442822.2 ENST00000375015.4 ENST00000533191.1	C6orf10	chromosome 6 open reading frame 10
chr5_+_172571445	0.02	ENST00000231668.9 ENST00000351486.5 ENST00000352523.6 ENST00000393770.4	BNIP1	BCL2/adenovirus E1B 19kDa interacting protein 1
chr15_-_89755034	0.02	ENST00000563254.1	RLBP1	retinaldehyde binding protein 1
chr20_-_23731569	0.01	ENST00000304749.2	CST1	cystatin SN
chr2_+_210444142	0.01	ENST00000360351.4 ENST00000361559.4	MAP2	microtubule-associated protein 2
chr5_-_140053152	0.01	ENST00000542735.1	DND1	DND microRNA-mediated repression inhibitor 1
chr20_-_23669590	0.01	ENST00000217423.3	CST4	cystatin S
chr4_+_76932326	0.00	ENST00000513353.1 ENST00000341029.5	ART3	ADP-ribosyltransferase 3
chrX_+_150345054	0.00	ENST00000218316.3	GPR50	G protein-coupled receptor 50

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	7.0	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.8	12.7	GO:0097512	cardiac myofibril(GO:0097512)
0.3	0.9	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
0.2	1.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.8	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	0.7	GO:0070436	Grb2-EGFR complex(GO:0070436)
0.1	0.7	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	6.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	0.8	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	1.0	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.1	2.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.1	0.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	1.6	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0005927	muscle tendon junction(GO:0005927)
0.0	1.4	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.3	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0043196	varicosity(GO:0043196)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.3	GO:0043194	axon initial segment(GO:0043194)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	1.4	GO:0005604	basement membrane(GO:0005604)
0.0	1.8	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.2	GO:0033276	transcription factor TFTC complex(GO:0033276)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	4.6	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.7	7.8	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.4	12.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.4	1.1	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.3	3.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.2	2.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.2	1.3	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2	1.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	1.4	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.5	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.1	0.6	GO:1903135	cupric ion binding(GO:1903135)
0.1	5.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	0.3	GO:0005457	GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1	0.8	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	4.7	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	0.4	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.1	0.2	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.2	GO:0004947	bradykinin receptor activity(GO:0004947)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.6	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.4	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.4	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	1.0	GO:0001671	ATPase activator activity(GO:0001671)
0.0	1.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.3	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	3.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.7	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	1.3	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.1	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.8	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.7	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0017162	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0045159	myosin II binding(GO:0045159)
0.0	0.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	1.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	1.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	7.0	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.2	4.6	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	6.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.4	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	1.5	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.4	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	3.9	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	7.0	GO:1904764	negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.7	12.7	GO:0007021	tubulin complex assembly(GO:0007021)
0.4	3.1	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.4	4.6	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.3	3.1	GO:0035799	ureter maturation(GO:0035799)
0.3	1.4	GO:1900535	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3	1.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.3	1.1	GO:0099640	axo-dendritic protein transport(GO:0099640)
0.3	1.1	GO:0009956	radial pattern formation(GO:0009956)
0.2	1.9	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2	0.9	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.2	1.3	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.2	0.6	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2	0.8	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.2	0.8	GO:0002159	desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.1	6.4	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1	1.5	GO:1904869	regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1	0.7	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.3	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
0.1	0.3	GO:0045210	negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.1	0.3	GO:0015783	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1	0.3	GO:0071698	olfactory placode formation(GO:0030910) myotome development(GO:0061055) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1	0.4	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.4	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.1	0.4	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.1	0.2	GO:0007412	axon target recognition(GO:0007412)
0.1	1.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.5	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.1	0.3	GO:1900827	positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	0.3	GO:0043335	protein unfolding(GO:0043335)
0.1	0.6	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.1	1.8	GO:0071711	basement membrane organization(GO:0071711)
0.1	1.6	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.4	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0032072	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0	0.6	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	1.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.2	GO:0044858	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0	0.1	GO:0010845	positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0	0.3	GO:1901673	regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.0	0.7	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.3	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	3.5	GO:0006997	nucleus organization(GO:0006997)
0.0	0.2	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.0	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.2	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.3	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.4	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.2	GO:0010992	ubiquitin homeostasis(GO:0010992)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	8.4	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	2.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.1	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	1.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.6	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development