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ENCODE cell lines, expression (Ernst 2011)

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Results for INSM1

Z-value: 0.65

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Transcription factors associated with INSM1

Gene Symbol Gene ID Gene Info
INSM1
ENSG00000173404.3 INSM1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
INSM1hg19_v2_chr20_+_20348740_203487650.097.4e-01Click!

Activity profile of INSM1 motif

Sorted Z-values of INSM1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of INSM1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_123691439 2.03 ENST00000540010.1
 TRAF1
 TNF receptor-associated factor 1
chr15_+_89182178 1.83 ENST00000559876.1
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr15_+_89181974 1.75 ENST00000306072.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 1.67 ENST00000379224.5
 ISG20
 interferon stimulated exonuclease gene 20kDa
chr9_-_37034028 1.20 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
 PAX5
 paired box 5
chr14_+_31343951 1.17 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
 COCH
 cochlin
chr14_+_65879668 1.06 ENST00000553924.1
ENST00000358307.2
ENST00000557338.1
ENST00000554610.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr8_+_28174649 1.04 ENST00000301908.3
 PNOC
 prepronociceptin
chr14_+_31343747 1.04 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
 COCH
 cochlin
chr6_-_29595779 0.92 ENST00000355973.3
ENST00000377012.4
 GABBR1
 gamma-aminobutyric acid (GABA) B receptor, 1
chr8_-_103136481 0.85 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
 NCALD
 neurocalcin delta
chr1_+_65613217 0.78 ENST00000545314.1
 AK4
 adenylate kinase 4
chr8_-_57123815 0.77 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1
 pleiomorphic adenoma gene 1
chr1_+_65613340 0.72 ENST00000546702.1
 AK4
 adenylate kinase 4
chr19_+_10197463 0.61 ENST00000590378.1
ENST00000397881.3
 C19orf66
 chromosome 19 open reading frame 66
chr5_-_175964366 0.58 ENST00000274811.4
 RNF44
 ring finger protein 44
chr1_-_236445251 0.57 ENST00000354619.5
ENST00000327333.8
 ERO1LB
 ERO1-like beta (S. cerevisiae)
chr14_+_65879437 0.57 ENST00000394585.1
 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr3_+_14989186 0.56 ENST00000435454.1
ENST00000323373.6
 NR2C2
 nuclear receptor subfamily 2, group C, member 2
chr10_+_35416223 0.54 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
 CREM
 cAMP responsive element modulator
chr8_-_101571933 0.54 ENST00000520311.1
 ANKRD46
 ankyrin repeat domain 46
chr2_-_27435125 0.51 ENST00000414408.1
ENST00000310574.3
 SLC5A6
 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr19_+_14142535 0.51 ENST00000263379.2
 IL27RA
 interleukin 27 receptor, alpha
chr2_-_73511559 0.47 ENST00000521871.1
 FBXO41
 F-box protein 41
chr4_-_151936416 0.45 ENST00000510413.1
ENST00000507224.1
 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
chr19_+_50887585 0.45 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
 POLD1
 polymerase (DNA directed), delta 1, catalytic subunit
chr15_-_70388943 0.43 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
 TLE3
 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr11_-_46142948 0.43 ENST00000257821.4
 PHF21A
 PHD finger protein 21A
chr12_+_53773944 0.42 ENST00000551969.1
ENST00000327443.4
 SP1
 Sp1 transcription factor
chr12_+_70760056 0.42 ENST00000258111.4
 KCNMB4
 potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr4_-_151936865 0.42 ENST00000535741.1
 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
chr2_-_25475120 0.41 ENST00000380746.4
ENST00000402667.1
 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
chr7_-_128694927 0.40 ENST00000471166.1
ENST00000265388.5
 TNPO3
 transportin 3
chr17_+_46184911 0.39 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
 SNX11
 sorting nexin 11
chr1_-_23886285 0.39 ENST00000374561.5
 ID3
 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr5_+_137688285 0.37 ENST00000314358.5
 KDM3B
 lysine (K)-specific demethylase 3B
chr12_-_92539614 0.37 ENST00000256015.3
 BTG1
 B-cell translocation gene 1, anti-proliferative
chr20_-_45981138 0.35 ENST00000446994.2
 ZMYND8
 zinc finger, MYND-type containing 8
chr5_-_150466692 0.35 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
 TNIP1
 TNFAIP3 interacting protein 1
chr17_-_73389854 0.34 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
 GRB2
 growth factor receptor-bound protein 2
chr11_+_118307179 0.34 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
 KMT2A
 lysine (K)-specific methyltransferase 2A
chr10_+_76585303 0.33 ENST00000372725.1
 KAT6B
 K(lysine) acetyltransferase 6B
chr3_-_15374033 0.33 ENST00000253688.5
ENST00000383791.3
 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
chr10_+_35415978 0.33 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
 CREM
 cAMP responsive element modulator
chr19_+_10196981 0.32 ENST00000591813.1
 C19orf66
 chromosome 19 open reading frame 66
chr17_-_73389737 0.32 ENST00000392563.1
 GRB2
 growth factor receptor-bound protein 2
chr6_-_41863098 0.32 ENST00000373006.1
 USP49
 ubiquitin specific peptidase 49
chr9_-_98269481 0.32 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
 PTCH1
 patched 1
chr10_+_35415719 0.30 ENST00000474362.1
ENST00000374721.3
 CREM
 cAMP responsive element modulator
chr7_-_128695147 0.29 ENST00000482320.1
ENST00000393245.1
ENST00000471234.1
 TNPO3
 transportin 3
chr8_+_28174496 0.28 ENST00000518479.1
 PNOC
 prepronociceptin
chr17_-_62493131 0.28 ENST00000539111.2
 POLG2
 polymerase (DNA directed), gamma 2, accessory subunit
chr12_-_6960407 0.27 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
 CDCA3
 cell division cycle associated 3
chr13_-_52027134 0.26 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6
 integrator complex subunit 6
chr11_+_117049445 0.26 ENST00000324225.4
ENST00000532960.1
 SIDT2
 SID1 transmembrane family, member 2
chr5_+_154238149 0.26 ENST00000519430.1
ENST00000520671.1
ENST00000521583.1
ENST00000518028.1
ENST00000519404.1
ENST00000519394.1
ENST00000518775.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr11_-_65430251 0.25 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
 RELA
 v-rel avian reticuloendotheliosis viral oncogene homolog A
chr17_-_47755436 0.24 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
 SPOP
 speckle-type POZ protein
chr19_-_55881741 0.23 ENST00000264563.2
ENST00000590625.1
ENST00000585513.1
 IL11
 interleukin 11
chr17_-_56606705 0.23 ENST00000317268.3
 SEPT4
 septin 4
chr12_-_118810688 0.22 ENST00000542532.1
ENST00000392533.3
 TAOK3
 TAO kinase 3
chr14_-_21566731 0.21 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr22_+_47158578 0.21 ENST00000355704.3
 TBC1D22A
 TBC1 domain family, member 22A
chr11_-_65430554 0.21 ENST00000308639.9
ENST00000406246.3
 RELA
 v-rel avian reticuloendotheliosis viral oncogene homolog A
chr17_-_56606639 0.21 ENST00000579371.1
 SEPT4
 septin 4
chr20_+_44657845 0.20 ENST00000243964.3
 SLC12A5
 solute carrier family 12 (potassium/chloride transporter), member 5
chr15_+_27216297 0.20 ENST00000333743.6
 GABRG3
 gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr11_-_46142615 0.20 ENST00000529734.1
ENST00000323180.6
 PHF21A
 PHD finger protein 21A
chr7_+_86273700 0.20 ENST00000546348.1
 GRM3
 glutamate receptor, metabotropic 3
chr17_-_56606664 0.20 ENST00000580844.1
 SEPT4
 septin 4
chr12_+_53774423 0.20 ENST00000426431.2
 SP1
 Sp1 transcription factor
chr12_+_120105558 0.19 ENST00000229328.5
ENST00000541640.1
 PRKAB1
 protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr13_-_31736132 0.19 ENST00000429785.2
 HSPH1
 heat shock 105kDa/110kDa protein 1
chr2_-_72375167 0.18 ENST00000001146.2
 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
chr1_+_168148273 0.18 ENST00000367830.3
 TIPRL
 TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr12_-_52715179 0.18 ENST00000293670.3
 KRT83
 keratin 83
chr12_+_7342178 0.18 ENST00000266563.5
ENST00000543974.1
 PEX5
 peroxisomal biogenesis factor 5
chr19_+_10196781 0.17 ENST00000253110.11
 C19orf66
 chromosome 19 open reading frame 66
chr1_-_154531095 0.17 ENST00000292211.4
 UBE2Q1
 ubiquitin-conjugating enzyme E2Q family member 1
chr11_-_47399942 0.16 ENST00000227163.4
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chr4_+_619386 0.16 ENST00000496514.1
 PDE6B
 phosphodiesterase 6B, cGMP-specific, rod, beta
chr7_+_86273952 0.16 ENST00000536043.1
 GRM3
 glutamate receptor, metabotropic 3
chr17_-_4890649 0.16 ENST00000361571.5
 CAMTA2
 calmodulin binding transcription activator 2
chr5_+_154238042 0.16 ENST00000519211.1
ENST00000522458.1
ENST00000519903.1
ENST00000521450.1
ENST00000403027.2
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr6_+_108881012 0.16 ENST00000343882.6
 FOXO3
 forkhead box O3
chr13_-_31736027 0.16 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
 HSPH1
 heat shock 105kDa/110kDa protein 1
chr10_+_91061712 0.16 ENST00000371826.3
 IFIT2
 interferon-induced protein with tetratricopeptide repeats 2
chr1_+_220863187 0.16 ENST00000294889.5
 C1orf115
 chromosome 1 open reading frame 115
chr6_+_32938692 0.16 ENST00000443797.2
 BRD2
 bromodomain containing 2
chr9_-_98269699 0.16 ENST00000429896.2
 PTCH1
 patched 1
chr4_+_56815102 0.16 ENST00000257287.4
 CEP135
 centrosomal protein 135kDa
chr5_+_154238096 0.15 ENST00000517568.1
ENST00000524105.1
ENST00000285896.6
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr10_+_88516396 0.15 ENST00000372037.3
 BMPR1A
 bone morphogenetic protein receptor, type IA
chr22_+_47158518 0.15 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
 TBC1D22A
 TBC1 domain family, member 22A
chr8_-_120685608 0.14 ENST00000427067.2
 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
chr12_+_7342441 0.14 ENST00000412720.2
ENST00000396637.3
 PEX5
 peroxisomal biogenesis factor 5
chr4_+_26322409 0.14 ENST00000514807.1
ENST00000348160.4
ENST00000509158.1
ENST00000355476.3
 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
chr22_-_36903101 0.13 ENST00000397224.4
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr9_+_37650945 0.13 ENST00000377765.3
 FRMPD1
 FERM and PDZ domain containing 1
chrX_+_146993449 0.13 ENST00000218200.8
ENST00000370471.3
ENST00000370477.1
 FMR1
 fragile X mental retardation 1
chr17_-_4890919 0.13 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
 CAMTA2
 calmodulin binding transcription activator 2
chr18_-_34408802 0.12 ENST00000590842.1
 TPGS2
 tubulin polyglutamylase complex subunit 2
chr7_+_86274145 0.12 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
 GRM3
 glutamate receptor, metabotropic 3
chr9_+_131452239 0.12 ENST00000372688.4
ENST00000372686.5
 SET
 SET nuclear oncogene
chr19_+_42817527 0.12 ENST00000598766.1
 TMEM145
 transmembrane protein 145
chr14_-_104313824 0.11 ENST00000553739.1
ENST00000202556.9
 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
chr1_+_10490779 0.11 ENST00000477755.1
 APITD1
 apoptosis-inducing, TAF9-like domain 1
chr21_-_46238034 0.11 ENST00000332859.6
 SUMO3
 small ubiquitin-like modifier 3
chr11_-_118972575 0.11 ENST00000432443.2
 DPAGT1
 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr11_+_10772534 0.10 ENST00000361367.2
 CTR9
 CTR9, Paf1/RNA polymerase II complex component
chr1_-_154474589 0.10 ENST00000304760.2
 SHE
 Src homology 2 domain containing E
chr15_-_43802769 0.10 ENST00000263801.3
 TP53BP1
 tumor protein p53 binding protein 1
chr6_+_32938665 0.10 ENST00000374831.4
ENST00000395289.2
 BRD2
 bromodomain containing 2
chr15_-_65426174 0.10 ENST00000204549.4
 PDCD7
 programmed cell death 7
chr4_+_619347 0.10 ENST00000255622.6
 PDE6B
 phosphodiesterase 6B, cGMP-specific, rod, beta
chr7_+_94536898 0.09 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
 PPP1R9A
 protein phosphatase 1, regulatory subunit 9A
chr11_-_47400078 0.09 ENST00000378538.3
 SPI1
 spleen focus forming virus (SFFV) proviral integration oncogene
chr22_-_36903069 0.09 ENST00000216187.6
ENST00000423980.1
 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
chr17_+_27369918 0.09 ENST00000323372.4
 PIPOX
 pipecolic acid oxidase
chr4_+_174089904 0.09 ENST00000265000.4
 GALNT7
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr16_+_67360712 0.09 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
 LRRC36
 leucine rich repeat containing 36
chr14_+_96152754 0.08 ENST00000340722.7
 TCL1B
 T-cell leukemia/lymphoma 1B
chr12_+_7342271 0.08 ENST00000434354.2
ENST00000544456.1
ENST00000545574.1
ENST00000420616.2
 PEX5
 peroxisomal biogenesis factor 5
chr1_+_10490441 0.08 ENST00000470413.2
ENST00000309048.3
 APITD1-CORT
APITD1
 APITD1-CORT readthrough
apoptosis-inducing, TAF9-like domain 1
chr19_+_41284121 0.08 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
 RAB4B
 RAB4B, member RAS oncogene family
chr6_+_155054459 0.08 ENST00000367178.3
ENST00000417268.1
ENST00000367186.4
 SCAF8
 SR-related CTD-associated factor 8
chr2_+_232575128 0.07 ENST00000412128.1
 PTMA
 prothymosin, alpha
chr17_-_37382105 0.07 ENST00000333461.5
 STAC2
 SH3 and cysteine rich domain 2
chrX_+_49020121 0.07 ENST00000415364.1
ENST00000376338.3
ENST00000425285.1
 MAGIX
 MAGI family member, X-linked
chr1_-_1051455 0.07 ENST00000379339.1
ENST00000480643.1
ENST00000434641.1
ENST00000421241.2
 C1orf159
 chromosome 1 open reading frame 159
chr19_+_19626531 0.07 ENST00000507754.4
 NDUFA13
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr9_-_112083229 0.07 ENST00000374566.3
ENST00000374557.4
 EPB41L4B
 erythrocyte membrane protein band 4.1 like 4B
chr18_-_51750948 0.07 ENST00000583046.1
ENST00000398398.2
 MBD2
 methyl-CpG binding domain protein 2
chr1_-_1051736 0.06 ENST00000448924.1
ENST00000294576.5
ENST00000437760.1
ENST00000462097.1
ENST00000475119.1
 C1orf159
 chromosome 1 open reading frame 159
chr2_+_208394794 0.06 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
 CREB1
 cAMP responsive element binding protein 1
chr7_-_91509986 0.06 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
 MTERF
 mitochondrial transcription termination factor
chr6_-_94129244 0.06 ENST00000369303.4
ENST00000369297.1
 EPHA7
 EPH receptor A7
chr10_-_103603568 0.06 ENST00000356640.2
 KCNIP2
 Kv channel interacting protein 2
chr5_-_11904152 0.05 ENST00000304623.8
ENST00000458100.2
 CTNND2
 catenin (cadherin-associated protein), delta 2
chrX_+_153059608 0.05 ENST00000370087.1
 SSR4
 signal sequence receptor, delta
chr5_+_154237778 0.05 ENST00000523698.1
ENST00000517876.1
ENST00000520472.1
 CNOT8
 CCR4-NOT transcription complex, subunit 8
chr22_+_44351419 0.05 ENST00000396202.3
 SAMM50
 SAMM50 sorting and assembly machinery component
chr9_-_140115775 0.04 ENST00000391553.1
ENST00000392827.1
 RNF208
 ring finger protein 208
chr17_-_8868991 0.04 ENST00000447110.1
 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
chr12_+_7341759 0.04 ENST00000455147.2
ENST00000540398.1
 PEX5
 peroxisomal biogenesis factor 5
chr10_-_103603677 0.04 ENST00000358038.3
 KCNIP2
 Kv channel interacting protein 2
chr8_-_145550571 0.04 ENST00000332324.4
 DGAT1
 diacylglycerol O-acyltransferase 1
chr1_-_205325850 0.03 ENST00000537168.1
 KLHDC8A
 kelch domain containing 8A
chr1_+_10490127 0.03 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
 APITD1
APITD1-CORT
 apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr20_+_35202909 0.03 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
 TGIF2-C20orf24
TGIF2
 TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr5_-_11904100 0.03 ENST00000359640.2
 CTNND2
 catenin (cadherin-associated protein), delta 2
chr12_+_51985001 0.03 ENST00000354534.6
 SCN8A
 sodium channel, voltage gated, type VIII, alpha subunit
chr1_-_160040038 0.03 ENST00000368089.3
 KCNJ10
 potassium inwardly-rectifying channel, subfamily J, member 10
chr1_+_153750622 0.02 ENST00000532853.1
 SLC27A3
 solute carrier family 27 (fatty acid transporter), member 3
chrX_-_153059811 0.01 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
 IDH3G
 isocitrate dehydrogenase 3 (NAD+) gamma
chr11_-_66445219 0.01 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
 RBM4B
 RNA binding motif protein 4B
chr21_-_46237959 0.01 ENST00000397898.3
ENST00000411651.2
 SUMO3
 small ubiquitin-like modifier 3
chr18_+_46065483 0.01 ENST00000382998.4
 CTIF
 CBP80/20-dependent translation initiation factor
chr17_-_42992856 0.01 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
 GFAP
 glial fibrillary acidic protein
chr19_+_35630022 0.01 ENST00000589209.1
 FXYD1
 FXYD domain containing ion transport regulator 1
chrX_+_153060090 0.01 ENST00000370086.3
ENST00000370085.3
 SSR4
 signal sequence receptor, delta
chr3_+_185304059 0.01 ENST00000427465.2
 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
chr11_+_32914579 0.00 ENST00000399302.2
 QSER1
 glutamine and serine rich 1

Gene Ontology Analysis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0008859 exoribonuclease II activity(GO:0008859)
0.5 1.6 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.4 1.5 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.3 GO:0001515 opioid peptide activity(GO:0001515)
0.2 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 2.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.6 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0031386 protein tag(GO:0031386)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.6 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 1.5 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 0.6 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0021997 response to chlorate(GO:0010157) neural plate axis specification(GO:0021997)
0.1 0.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.5 GO:0014040 positive regulation of Schwann cell differentiation(GO:0014040)
0.1 0.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.2 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.1 GO:1901189 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.4 GO:1903751 negative regulation of establishment of protein localization to mitochondrion(GO:1903748) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.0 0.5 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653) regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0019474 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.9 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 5.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 0.5 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 5.2 GO:0015030 Cajal body(GO:0015030)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)