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ENCODE cell lines, expression (Ernst 2011)

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Results for IRX3

Z-value: 1.21

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Transcription factors associated with IRX3

Gene Symbol Gene ID Gene Info
ENSG00000177508.11 IRX3

Activity profile of IRX3 motif

Sorted Z-values of IRX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_38172863 4.36 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr11_+_35201826 4.22 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr3_-_127541194 3.27 ENST00000453507.2
MGLL
monoglyceride lipase
chr4_-_143481822 3.18 ENST00000510812.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr12_-_91574142 3.16 ENST00000547937.1
DCN
decorin
chr11_+_35211429 2.99 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr15_+_49170083 2.84 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr12_-_91546926 2.69 ENST00000550758.1
DCN
decorin
chr12_-_91573316 2.66 ENST00000393155.1
DCN
decorin
chr12_-_91573132 2.66 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr4_+_169842707 2.56 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr11_-_35547572 2.49 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr12_-_91573249 2.23 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr5_+_35856951 2.19 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr3_+_8543393 2.19 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr2_+_189839046 2.17 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr1_+_158985457 2.16 ENST00000567661.1
ENST00000474473.1
IFI16
interferon, gamma-inducible protein 16
chr11_+_114166536 2.15 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr3_-_127441406 2.01 ENST00000487473.1
ENST00000484451.1
MGLL
monoglyceride lipase
chr11_-_111782696 1.94 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr12_+_75874460 1.78 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr3_+_157154578 1.77 ENST00000295927.3
PTX3
pentraxin 3, long
chr10_-_90712520 1.74 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_+_8543533 1.64 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr4_+_169418195 1.64 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr1_+_158979686 1.63 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr3_+_158787041 1.57 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr9_-_88715044 1.56 ENST00000388711.3
ENST00000466178.1
GOLM1
golgi membrane protein 1
chr11_-_111782484 1.55 ENST00000533971.1
CRYAB
crystallin, alpha B
chr2_+_234621551 1.46 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr10_+_60272814 1.46 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr3_+_8543561 1.36 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr17_-_33760164 1.33 ENST00000445092.1
ENST00000394562.1
ENST00000447040.2
SLFN12
schlafen family member 12
chr3_-_123512688 1.30 ENST00000475616.1
MYLK
myosin light chain kinase
chr4_+_169418255 1.27 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr5_+_135385202 1.22 ENST00000514554.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr17_-_29648761 1.19 ENST00000247270.3
ENST00000462804.2
EVI2A
ecotropic viral integration site 2A
chr20_+_19867150 1.16 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr1_+_196788887 1.16 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr2_-_190044480 1.14 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_+_67420441 1.13 ENST00000558894.1
SMAD3
SMAD family member 3
chr11_+_111783450 1.13 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr10_+_13628933 1.13 ENST00000417658.1
ENST00000320054.4
PRPF18
pre-mRNA processing factor 18
chr15_-_56757329 1.12 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr18_-_21891460 1.08 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr5_+_32788945 1.07 ENST00000326958.1
AC026703.1
AC026703.1
chr15_+_25200074 1.06 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr17_-_33760269 1.04 ENST00000452764.3
SLFN12
schlafen family member 12
chr2_+_191792376 1.03 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr8_-_101962777 1.03 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr6_-_144329531 1.02 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1
pleiomorphic adenoma gene-like 1
chr1_+_160175201 1.01 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr1_+_160175117 1.01 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr14_+_96722152 0.99 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr1_+_171060018 0.99 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
FMO3
flavin containing monooxygenase 3
chr11_-_104905840 0.98 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr12_+_1738363 0.96 ENST00000397196.2
WNT5B
wingless-type MMTV integration site family, member 5B
chr3_+_138066539 0.96 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr11_+_111782934 0.96 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr8_+_132952112 0.95 ENST00000520362.1
ENST00000519656.1
EFR3A
EFR3 homolog A (S. cerevisiae)
chr15_+_25200108 0.94 ENST00000577949.1
ENST00000338094.6
ENST00000338327.4
ENST00000579070.1
ENST00000577565.1
SNURF
SNRPN
SNRPN upstream reading frame protein
small nuclear ribonucleoprotein polypeptide N
chr9_-_21975088 0.91 ENST00000304494.5
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr18_-_53303123 0.87 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr10_-_103815874 0.87 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr2_+_233527443 0.85 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr11_+_60223225 0.84 ENST00000524807.1
ENST00000345732.4
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr12_+_56114151 0.84 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr13_+_73629107 0.83 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr7_+_40174565 0.81 ENST00000309930.5
ENST00000401647.2
ENST00000335693.4
ENST00000413931.1
ENST00000416370.1
ENST00000540834.1
C7orf10
succinylCoA:glutarate-CoA transferase
chr1_-_154909329 0.81 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr12_+_56114189 0.81 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr9_+_4679555 0.80 ENST00000381858.1
ENST00000381854.3
CDC37L1
cell division cycle 37-like 1
chr2_-_16804320 0.80 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr17_-_29641104 0.80 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr11_-_14358620 0.79 ENST00000531421.1
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr1_+_87458692 0.77 ENST00000370548.2
ENST00000356813.4
RP5-1052I5.2
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr16_+_56969284 0.76 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr17_+_18601299 0.75 ENST00000572555.1
ENST00000395902.3
ENST00000449552.2
TRIM16L
tripartite motif containing 16-like
chr11_-_104972158 0.74 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr19_-_22379753 0.74 ENST00000397121.2
ZNF676
zinc finger protein 676
chr8_-_108510224 0.71 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr2_-_158300556 0.71 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr12_-_52867569 0.71 ENST00000252250.6
KRT6C
keratin 6C
chr7_-_41742697 0.71 ENST00000242208.4
INHBA
inhibin, beta A
chr10_+_13628921 0.70 ENST00000378572.3
PRPF18
pre-mRNA processing factor 18
chr6_-_32920794 0.66 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr1_-_62190793 0.66 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr11_+_86013253 0.65 ENST00000533986.1
ENST00000278483.3
C11orf73
chromosome 11 open reading frame 73
chr19_-_43708378 0.65 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr12_+_5541267 0.65 ENST00000423158.3
NTF3
neurotrophin 3
chr11_-_61647935 0.65 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr2_-_231090344 0.65 ENST00000540870.1
ENST00000416610.1
SP110
SP110 nuclear body protein
chr17_-_29641084 0.64 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr16_+_50300427 0.64 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr12_-_10007448 0.64 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr2_-_86094764 0.63 ENST00000393808.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_144173162 0.63 ENST00000356801.6
NBPF8
neuroblastoma breakpoint family, member 8
chr4_+_41361616 0.63 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr7_+_44240520 0.62 ENST00000496112.1
ENST00000223369.2
YKT6
YKT6 v-SNARE homolog (S. cerevisiae)
chr1_+_160709055 0.60 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7
SLAM family member 7
chr1_-_9129735 0.59 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_23504176 0.58 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr2_+_234637754 0.58 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_-_170924888 0.58 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr4_-_70826725 0.57 ENST00000353151.3
CSN2
casein beta
chr4_+_41992489 0.57 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chrX_+_99899180 0.57 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr8_+_125463048 0.56 ENST00000328599.3
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr7_+_120591170 0.55 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr1_+_196912902 0.55 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr1_+_145524891 0.55 ENST00000369304.3
ITGA10
integrin, alpha 10
chr13_-_36429763 0.54 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr12_+_16109519 0.54 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chr17_-_63822563 0.53 ENST00000317442.8
CEP112
centrosomal protein 112kDa
chr14_-_106926724 0.53 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_-_113594279 0.53 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr5_+_140810132 0.53 ENST00000252085.3
PCDHGA12
protocadherin gamma subfamily A, 12
chr1_+_160709029 0.52 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr14_-_106692191 0.51 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr15_+_25101698 0.51 ENST00000400097.1
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr3_-_48936272 0.50 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr2_-_130886795 0.50 ENST00000409914.2
POTEF
POTE ankyrin domain family, member F
chr14_-_106845789 0.49 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr1_-_230513367 0.48 ENST00000321327.2
ENST00000525115.1
PGBD5
piggyBac transposable element derived 5
chr14_+_96722539 0.48 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr10_+_91092241 0.47 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_160590469 0.47 ENST00000409591.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr11_-_87908600 0.47 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr4_+_75480629 0.47 ENST00000380846.3
AREGB
amphiregulin B
chr7_+_116502527 0.46 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_+_21590549 0.46 ENST00000545178.1
ENST00000240651.9
PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr6_-_32634425 0.45 ENST00000399082.3
ENST00000399079.3
ENST00000374943.4
ENST00000434651.2
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr6_-_111804393 0.45 ENST00000368802.3
ENST00000368805.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr14_-_67878917 0.45 ENST00000216446.4
PLEK2
pleckstrin 2
chr15_-_81616446 0.44 ENST00000302824.6
STARD5
StAR-related lipid transfer (START) domain containing 5
chr1_+_155829286 0.44 ENST00000368324.4
SYT11
synaptotagmin XI
chr9_-_135230336 0.44 ENST00000224140.5
ENST00000372169.2
ENST00000393220.1
SETX
senataxin
chr1_-_148025848 0.44 ENST00000310701.10
ENST00000369219.1
ENST00000444640.1
ENST00000431121.1
ENST00000436356.1
ENST00000448574.1
ENST00000458135.1
ENST00000392972.3
ENST00000426874.1
NBPF14
neuroblastoma breakpoint family, member 14
chr16_-_33647696 0.44 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr7_+_144052381 0.44 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr14_-_106963409 0.44 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr16_+_33605231 0.43 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr5_-_93447333 0.43 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr14_-_106471723 0.43 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr9_-_95298314 0.42 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr3_+_122044084 0.42 ENST00000264474.3
ENST00000479204.1
CSTA
cystatin A (stefin A)
chr1_+_144151520 0.41 ENST00000369372.4
NBPF8
neuroblastoma breakpoint family, member 8
chr6_+_29426230 0.41 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr6_+_127587755 0.41 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146
ring finger protein 146
chr1_-_201438282 0.41 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr1_-_197036364 0.41 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr1_+_53480598 0.40 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr6_-_154677900 0.39 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr18_+_21529811 0.39 ENST00000588004.1
LAMA3
laminin, alpha 3
chr9_-_95244781 0.39 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr8_+_22429205 0.39 ENST00000520207.1
SORBS3
sorbin and SH3 domain containing 3
chr7_+_80267973 0.39 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_21757774 0.38 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr16_+_81070792 0.38 ENST00000564241.1
ENST00000565237.1
ATMIN
ATM interactor
chr4_+_75310851 0.38 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr6_-_117747015 0.37 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr19_-_20748541 0.37 ENST00000427401.4
ENST00000594419.1
ZNF737
zinc finger protein 737
chr1_-_46598371 0.37 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr4_+_88754069 0.37 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr1_+_87012753 0.37 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr3_+_142838091 0.37 ENST00000309575.3
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr7_+_55086703 0.37 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr18_-_28622774 0.37 ENST00000434452.1
DSC3
desmocollin 3
chr14_-_51562745 0.36 ENST00000298355.3
TRIM9
tripartite motif containing 9
chr9_-_13279589 0.36 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr13_+_21714653 0.35 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr7_+_77469439 0.35 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr2_+_234590556 0.35 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr16_-_30032610 0.35 ENST00000574405.1
DOC2A
double C2-like domains, alpha
chr10_-_112678976 0.34 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr3_-_27498235 0.34 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_-_115124257 0.34 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chrX_-_15402498 0.34 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr1_+_202317815 0.33 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr5_+_115420688 0.33 ENST00000274458.4
COMMD10
COMM domain containing 10
chr3_+_186383741 0.32 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr21_-_27462351 0.32 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr1_+_201924619 0.32 ENST00000367287.4
TIMM17A
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr1_+_77333117 0.32 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr19_-_45004556 0.31 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr4_-_69434245 0.31 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr11_+_114310237 0.31 ENST00000539119.1
REXO2
RNA exonuclease 2
chr2_-_86790593 0.31 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr3_-_50378235 0.30 ENST00000357043.2
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr3_-_185641681 0.30 ENST00000259043.7
TRA2B
transformer 2 beta homolog (Drosophila)
chr1_-_114414316 0.30 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr11_+_114310102 0.30 ENST00000265881.5
REXO2
RNA exonuclease 2
chr12_-_102224704 0.30 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr3_-_57583185 0.29 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr3_+_132316081 0.29 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr6_-_32784687 0.29 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr11_-_26743546 0.29 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr15_-_63448973 0.29 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr5_-_9630463 0.29 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr1_+_196857144 0.28 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4
complement factor H-related 4

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.0 13.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 1.8 GO:0071020 post-spliceosomal complex(GO:0071020)
0.4 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 1.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.7 GO:0072557 IPAF inflammasome complex(GO:0072557) NLRP1 inflammasome complex(GO:0072558)
0.2 0.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 3.5 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 1.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.5 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 5.9 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 3.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 4.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0046696 CBM complex(GO:0032449) lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.4 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:1990909 catenin complex(GO:0016342) Wnt signalosome(GO:1990909)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0036019 endolysosome(GO:0036019)
0.0 0.0 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 5.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 3.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806)
0.0 2.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 13.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.5 6.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 3.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 5.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 2.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:1990523 bone regeneration(GO:1990523)
1.1 13.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.9 7.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.8 5.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 1.8 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.4 3.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 0.8 GO:0032943 mononuclear cell proliferation(GO:0032943) lymphocyte proliferation(GO:0046651) leukocyte proliferation(GO:0070661)
0.4 2.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.4 0.4 GO:1990748 cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.4 0.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 1.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3 1.7 GO:0090131 mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.3 1.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.3 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 5.5 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 1.0 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 5.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 2.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 3.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.6 GO:1903487 regulation of lactation(GO:1903487)
0.2 0.7 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.5 GO:0002818 intracellular defense response(GO:0002818)
0.2 1.8 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.4 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.1 2.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 1.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.5 GO:0048871 multicellular organismal homeostasis(GO:0048871)
0.1 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.1 1.1 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.6 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 4.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.4 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.8 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.0 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.1 0.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 1.0 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599) coagulation(GO:0050817)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0071873 response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.4 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.2 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.2 GO:2000232 regulation of rRNA processing(GO:2000232)
0.1 3.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 3.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 1.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0001842 neural fold formation(GO:0001842)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0018212 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 2.8 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.2 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:1903593 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308) regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:0016032 viral process(GO:0016032)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0009914 hormone transport(GO:0009914)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.3 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.1 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.0 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) positive regulation of gap junction assembly(GO:1903598)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0042127 regulation of cell proliferation(GO:0042127)
0.0 0.7 GO:0097190 apoptotic signaling pathway(GO:0097190)
0.0 0.3 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0030031 cell projection assembly(GO:0030031)
0.0 0.1 GO:2000255 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.0 GO:0019605 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.0 1.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.0 GO:0002767 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.1 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.1 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.6 3.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6 1.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.5 2.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.5 1.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.4 5.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 24.3 GO:0005518 collagen binding(GO:0005518)
0.2 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 5.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.8 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.0 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.5 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 0.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 0.7 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.3 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.1 GO:0004040 amidase activity(GO:0004040)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 3.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.8 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763) IgE binding(GO:0019863)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 4.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0004979 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 7.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.