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ENCODE cell lines, expression (Ernst 2011)

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Results for ISX

Z-value: 0.41

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Transcription factors associated with ISX

Gene Symbol Gene ID Gene Info
ISX
ENSG00000175329.8 ISX

Activity profile of ISX motif

Sorted Z-values of ISX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ISX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_149095652 1.34 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr16_-_55866997 1.28 ENST00000360526.3
ENST00000361503.4
 CES1
 carboxylesterase 1
chr14_-_94789663 0.91 ENST00000557225.1
ENST00000341584.3
 SERPINA6
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr16_-_55867146 0.73 ENST00000422046.2
 CES1
 carboxylesterase 1
chr4_-_141348789 0.63 ENST00000414773.1
 CLGN
 calmegin
chr12_-_103310987 0.56 ENST00000307000.2
 PAH
 phenylalanine hydroxylase
chr4_-_141348999 0.50 ENST00000325617.5
 CLGN
 calmegin
chr2_+_217524323 0.42 ENST00000456764.1
 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
chrX_+_43515467 0.41 ENST00000338702.3
ENST00000542639.1
 MAOA
 monoamine oxidase A
chr10_-_99447024 0.40 ENST00000370626.3
 AVPI1
 arginine vasopressin-induced 1
chr6_+_148663729 0.39 ENST00000367467.3
 SASH1
 SAM and SH3 domain containing 1
chr20_-_17662705 0.39 ENST00000455029.2
 RRBP1
 ribosome binding protein 1
chr4_-_70080449 0.39 ENST00000446444.1
 UGT2B11
 UDP glucuronosyltransferase 2 family, polypeptide B11
chr12_-_51422017 0.35 ENST00000394904.3
 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr16_+_3070313 0.34 ENST00000326577.4
 TNFRSF12A
 tumor necrosis factor receptor superfamily, member 12A
chr3_-_151034734 0.29 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr16_+_3070356 0.28 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
 TNFRSF12A
 tumor necrosis factor receptor superfamily, member 12A
chr1_-_68698222 0.27 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS
 wntless Wnt ligand secretion mediator
chr1_-_209824643 0.26 ENST00000391911.1
ENST00000415782.1
 LAMB3
 laminin, beta 3
chr1_-_68698197 0.24 ENST00000370973.2
ENST00000370971.1
 WLS
 wntless Wnt ligand secretion mediator
chr20_+_44441304 0.24 ENST00000352551.5
 UBE2C
 ubiquitin-conjugating enzyme E2C
chr21_+_35014783 0.24 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
 ITSN1
 intersectin 1 (SH3 domain protein)
chr20_+_44441215 0.23 ENST00000356455.4
ENST00000405520.1
 UBE2C
 ubiquitin-conjugating enzyme E2C
chr9_+_34646624 0.22 ENST00000450095.2
ENST00000556278.1
 GALT
GALT
 galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr20_+_44441271 0.21 ENST00000335046.3
ENST00000243893.6
 UBE2C
 ubiquitin-conjugating enzyme E2C
chr5_-_95297534 0.21 ENST00000513343.1
ENST00000431061.2
 ELL2
 elongation factor, RNA polymerase II, 2
chr8_-_82395461 0.20 ENST00000256104.4
 FABP4
 fatty acid binding protein 4, adipocyte
chr11_+_77532233 0.19 ENST00000525409.1
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr9_+_34646651 0.19 ENST00000378842.3
 GALT
 galactose-1-phosphate uridylyltransferase
chr8_+_9413410 0.19 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr17_+_73452695 0.18 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
 KIAA0195
 KIAA0195
chr9_+_99212403 0.17 ENST00000375251.3
ENST00000375249.4
 HABP4
 hyaluronan binding protein 4
chr1_+_28261533 0.16 ENST00000411604.1
ENST00000373888.4
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr17_-_18266660 0.16 ENST00000582653.1
ENST00000352886.6
 SHMT1
 serine hydroxymethyltransferase 1 (soluble)
chr12_+_104680659 0.16 ENST00000526691.1
ENST00000531691.1
ENST00000388854.3
ENST00000354940.6
ENST00000526390.1
ENST00000531689.1
 TXNRD1
 thioredoxin reductase 1
chr22_+_36044411 0.16 ENST00000409652.4
 APOL6
 apolipoprotein L, 6
chr6_+_64345698 0.16 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
 PHF3
 PHD finger protein 3
chr7_+_150929550 0.16 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
 CHPF2
 chondroitin polymerizing factor 2
chr11_+_77532155 0.15 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr17_-_42277203 0.14 ENST00000587097.1
 ATXN7L3
 ataxin 7-like 3
chr6_-_49681235 0.14 ENST00000339139.4
 CRISP2
 cysteine-rich secretory protein 2
chr3_-_160823158 0.14 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_-_186733363 0.13 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
 SORBS2
 sorbin and SH3 domain containing 2
chr4_+_87515454 0.13 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr17_-_18266765 0.13 ENST00000354098.3
 SHMT1
 serine hydroxymethyltransferase 1 (soluble)
chr5_+_159848807 0.12 ENST00000352433.5
 PTTG1
 pituitary tumor-transforming 1
chr17_-_27418537 0.12 ENST00000408971.2
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chr14_+_32798547 0.12 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
 AKAP6
 A kinase (PRKA) anchor protein 6
chr1_-_150669604 0.12 ENST00000427665.1
ENST00000540514.1
 GOLPH3L
 golgi phosphoprotein 3-like
chr20_-_43133491 0.12 ENST00000411544.1
 SERINC3
 serine incorporator 3
chr5_-_95297678 0.11 ENST00000237853.4
 ELL2
 elongation factor, RNA polymerase II, 2
chr6_-_135271260 0.11 ENST00000265605.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr17_+_79650962 0.11 ENST00000329138.4
 HGS
 hepatocyte growth factor-regulated tyrosine kinase substrate
chrX_-_24690771 0.11 ENST00000379145.1
 PCYT1B
 phosphate cytidylyltransferase 1, choline, beta
chr17_-_48785216 0.11 ENST00000285243.6
 ANKRD40
 ankyrin repeat domain 40
chr17_-_18266797 0.11 ENST00000316694.3
ENST00000539052.1
 SHMT1
 serine hydroxymethyltransferase 1 (soluble)
chr12_+_3000037 0.11 ENST00000544943.1
ENST00000448120.2
 TULP3
 tubby like protein 3
chr11_-_62414070 0.10 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
 GANAB
 glucosidase, alpha; neutral AB
chr3_-_160823040 0.10 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_-_77005801 0.10 ENST00000392446.5
 CANT1
 calcium activated nucleotidase 1
chr12_+_69201923 0.10 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
 MDM2
 MDM2 oncogene, E3 ubiquitin protein ligase
chr1_+_28261492 0.10 ENST00000373894.3
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr16_+_3493611 0.10 ENST00000407558.4
ENST00000572169.1
ENST00000572757.1
ENST00000573593.1
ENST00000570372.1
ENST00000424546.2
ENST00000575733.1
ENST00000573201.1
ENST00000574950.1
ENST00000573580.1
ENST00000608722.1
 NAA60
NAA60
 N(alpha)-acetyltransferase 60, NatF catalytic subunit
N-alpha-acetyltransferase 60
chr14_+_70233810 0.09 ENST00000394366.2
ENST00000553548.1
ENST00000553369.1
ENST00000557154.1
ENST00000451983.2
ENST00000553635.1
 SRSF5
 serine/arginine-rich splicing factor 5
chr10_+_91461337 0.09 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
 KIF20B
 kinesin family member 20B
chr5_+_159848854 0.09 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
 PTTG1
 pituitary tumor-transforming 1
chr8_+_105235572 0.09 ENST00000523362.1
 RIMS2
 regulating synaptic membrane exocytosis 2
chr22_+_29138013 0.09 ENST00000216027.3
ENST00000398941.2
 HSCB
 HscB mitochondrial iron-sulfur cluster co-chaperone
chr3_-_46069223 0.09 ENST00000309285.3
 XCR1
 chemokine (C motif) receptor 1
chr2_-_183387430 0.09 ENST00000410103.1
 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
chr1_+_151735431 0.09 ENST00000321531.5
ENST00000315067.8
 OAZ3
 ornithine decarboxylase antizyme 3
chr3_+_113775576 0.09 ENST00000485050.1
ENST00000281273.4
 QTRTD1
 queuine tRNA-ribosyltransferase domain containing 1
chr12_-_10978957 0.09 ENST00000240619.2
 TAS2R10
 taste receptor, type 2, member 10
chr2_+_87135076 0.09 ENST00000409776.2
 RGPD1
 RANBP2-like and GRIP domain containing 1
chr1_+_28261621 0.08 ENST00000549094.1
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr6_-_135271219 0.08 ENST00000367847.2
ENST00000367845.2
 ALDH8A1
 aldehyde dehydrogenase 8 family, member A1
chr2_+_204571375 0.08 ENST00000374478.4
 CD28
 CD28 molecule
chr16_-_31105870 0.07 ENST00000394971.3
 VKORC1
 vitamin K epoxide reductase complex, subunit 1
chr13_+_38923959 0.07 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
 UFM1
 ubiquitin-fold modifier 1
chr14_+_104182061 0.07 ENST00000216602.6
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr17_-_2966901 0.07 ENST00000575751.1
 OR1D5
 olfactory receptor, family 1, subfamily D, member 5
chr17_+_73452545 0.07 ENST00000314256.7
 KIAA0195
 KIAA0195
chr16_-_31106211 0.07 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
 RP11-196G11.1
VKORC1
 Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr2_+_86947296 0.07 ENST00000283632.4
 RMND5A
 required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_+_160542821 0.06 ENST00000366963.4
 SLC22A1
 solute carrier family 22 (organic cation transporter), member 1
chr16_-_31106048 0.06 ENST00000300851.6
 VKORC1
 vitamin K epoxide reductase complex, subunit 1
chr12_+_52695617 0.06 ENST00000293525.5
 KRT86
 keratin 86
chr6_-_39693111 0.06 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
 KIF6
 kinesin family member 6
chr2_+_177015122 0.06 ENST00000468418.3
 HOXD3
 homeobox D3
chr1_+_155278625 0.06 ENST00000368356.4
ENST00000356657.6
 FDPS
 farnesyl diphosphate synthase
chr12_+_3000073 0.06 ENST00000397132.2
 TULP3
 tubby like protein 3
chr11_-_13517565 0.06 ENST00000282091.1
ENST00000529816.1
 PTH
 parathyroid hormone
chr1_+_87595433 0.05 ENST00000469312.2
ENST00000490006.2
 RP5-1052I5.1
 long intergenic non-protein coding RNA 1140
chr7_+_144052381 0.05 ENST00000498580.1
ENST00000056217.5
 ARHGEF5
 Rho guanine nucleotide exchange factor (GEF) 5
chr14_+_22964877 0.05 ENST00000390494.1
 TRAJ43
 T cell receptor alpha joining 43
chr14_+_104182105 0.05 ENST00000311141.2
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr5_-_98262240 0.05 ENST00000284049.3
 CHD1
 chromodomain helicase DNA binding protein 1
chr2_-_3521518 0.05 ENST00000382093.5
 ADI1
 acireductone dioxygenase 1
chr8_+_9953061 0.05 ENST00000522907.1
ENST00000528246.1
 MSRA
 methionine sulfoxide reductase A
chr3_+_37284668 0.05 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
 GOLGA4
 golgin A4
chr20_+_24449821 0.05 ENST00000376862.3
 SYNDIG1
 synapse differentiation inducing 1
chr6_+_160542870 0.04 ENST00000324965.4
ENST00000457470.2
 SLC22A1
 solute carrier family 22 (organic cation transporter), member 1
chr7_+_115862858 0.04 ENST00000393481.2
 TES
 testis derived transcript (3 LIM domains)
chr1_-_150669500 0.04 ENST00000271732.3
 GOLPH3L
 golgi phosphoprotein 3-like
chr10_-_114206649 0.04 ENST00000369404.3
ENST00000369405.3
 ZDHHC6
 zinc finger, DHHC-type containing 6
chr1_-_112281875 0.04 ENST00000527621.1
ENST00000534365.1
ENST00000357260.5
 FAM212B
 family with sequence similarity 212, member B
chr14_-_20801427 0.04 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
 CCNB1IP1
 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr8_+_9953214 0.04 ENST00000382490.5
 MSRA
 methionine sulfoxide reductase A
chr17_-_43045439 0.04 ENST00000253407.3
 C1QL1
 complement component 1, q subcomponent-like 1
chr16_-_58585513 0.03 ENST00000245138.4
ENST00000567285.1
 CNOT1
 CCR4-NOT transcription complex, subunit 1
chr3_+_148709128 0.03 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
 GYG1
 glycogenin 1
chr4_+_48018781 0.03 ENST00000295461.5
 NIPAL1
 NIPA-like domain containing 1
chr1_+_155278539 0.03 ENST00000447866.1
 FDPS
 farnesyl diphosphate synthase
chr1_-_197115818 0.03 ENST00000367409.4
ENST00000294732.7
 ASPM
 asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_+_135809835 0.03 ENST00000264158.8
ENST00000539493.1
ENST00000442034.1
ENST00000425393.1
 RAB3GAP1
 RAB3 GTPase activating protein subunit 1 (catalytic)
chr1_-_150849174 0.03 ENST00000515192.1
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr5_+_174151536 0.03 ENST00000239243.6
ENST00000507785.1
 MSX2
 msh homeobox 2
chr1_+_220267429 0.03 ENST00000366922.1
ENST00000302637.5
 IARS2
 isoleucyl-tRNA synthetase 2, mitochondrial
chr7_-_100493482 0.03 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
 ACHE
 acetylcholinesterase (Yt blood group)
chr12_+_15125954 0.03 ENST00000266395.2
 PDE6H
 phosphodiesterase 6H, cGMP-specific, cone, gamma
chr1_+_23345930 0.03 ENST00000356634.3
 KDM1A
 lysine (K)-specific demethylase 1A
chr21_+_35014706 0.03 ENST00000399353.1
ENST00000444491.1
ENST00000381318.3
 ITSN1
 intersectin 1 (SH3 domain protein)
chr3_-_15563229 0.02 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
 COLQ
 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr6_-_31125850 0.02 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
 CCHCR1
 coiled-coil alpha-helical rod protein 1
chr12_+_122688090 0.02 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr6_-_32095968 0.02 ENST00000375203.3
ENST00000375201.4
 ATF6B
 activating transcription factor 6 beta
chr1_-_150849047 0.02 ENST00000354396.2
ENST00000505755.1
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr4_-_100242549 0.02 ENST00000305046.8
ENST00000394887.3
 ADH1B
 alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_-_43833628 0.02 ENST00000413844.2
ENST00000372458.3
 ELOVL1
 ELOVL fatty acid elongase 1
chr14_-_73925225 0.02 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
 NUMB
 numb homolog (Drosophila)
chr14_+_32798462 0.02 ENST00000280979.4
 AKAP6
 A kinase (PRKA) anchor protein 6
chrX_-_6453159 0.02 ENST00000381089.3
ENST00000398729.1
 VCX3A
 variable charge, X-linked 3A
chr10_-_28571015 0.02 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chrX_-_8139308 0.02 ENST00000317103.4
 VCX2
 variable charge, X-linked 2
chr1_+_23345943 0.02 ENST00000400181.4
ENST00000542151.1
 KDM1A
 lysine (K)-specific demethylase 1A
chr14_-_24711806 0.02 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
 TINF2
 TERF1 (TRF1)-interacting nuclear factor 2
chr1_-_150849208 0.01 ENST00000358595.5
 ARNT
 aryl hydrocarbon receptor nuclear translocator
chr6_-_33385870 0.01 ENST00000488034.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr7_+_130020932 0.01 ENST00000484324.1
 CPA1
 carboxypeptidase A1 (pancreatic)
chr4_-_66536057 0.01 ENST00000273854.3
 EPHA5
 EPH receptor A5
chr6_-_33385902 0.01 ENST00000374500.5
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr10_+_124913793 0.01 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
 BUB3
 BUB3 mitotic checkpoint protein
chr22_-_29137771 0.01 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
 CHEK2
 checkpoint kinase 2
chr6_-_119256311 0.00 ENST00000316316.6
 MCM9
 minichromosome maintenance complex component 9
chr4_-_66536196 0.00 ENST00000511294.1
 EPHA5
 EPH receptor A5
chrX_-_139587225 0.00 ENST00000370536.2
 SOX3
 SRY (sex determining region Y)-box 3
chr6_-_33385655 0.00 ENST00000440279.3
ENST00000607266.1
 CUTA
 cutA divalent cation tolerance homolog (E. coli)
chr19_-_14785622 0.00 ENST00000443157.2
 EMR3
 egf-like module containing, mucin-like, hormone receptor-like 3

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0004771 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.6 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.4 GO:0070905 serine binding(GO:0070905)
0.1 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.2 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.2 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.4 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536)
0.1 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.6 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.8 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 1.1 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.0 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.4 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.0 GO:1903371 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions