ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
JDP2 Links Ensembl NCBI GeneCards UniProt	ENSG00000140044.8	JDP2

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Promoter	Score	Transcript	Gene	Gene Info
chr1_-_151965048	4.19	ENST00000368809.1	S100A10	S100 calcium binding protein A10
chr2_-_175712270	4.06	ENST00000295497.7 ENST00000444394.1	CHN1	chimerin 1
chr11_-_102668879	3.26	ENST00000315274.6	MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr7_+_134528635	3.09	ENST00000445569.2	CALD1	caldesmon 1
chr5_+_135394840	2.92	ENST00000503087.1	TGFBI	transforming growth factor, beta-induced, 68kDa
chr8_-_27472198	2.42	ENST00000519472.1 ENST00000523589.1 ENST00000522413.1 ENST00000523396.1 ENST00000560366.1	CLU	clusterin
chr3_-_32022733	2.19	ENST00000438237.2 ENST00000396556.2	OSBPL10	oxysterol binding protein-like 10
chr11_-_2950642	2.07	ENST00000314222.4	PHLDA2	pleckstrin homology-like domain, family A, member 2
chrY_+_15016725	1.82	ENST00000336079.3	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr12_-_54813229	1.73	ENST00000293379.4	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_49395705	1.68	ENST00000419349.1	GPX1	glutathione peroxidase 1
chr16_-_69760409	1.55	ENST00000561500.1 ENST00000439109.2 ENST00000564043.1 ENST00000379046.2 ENST00000379047.3	NQO1	NAD(P)H dehydrogenase, quinone 1
chr5_+_35856951	1.48	ENST00000303115.3 ENST00000343305.4 ENST00000506850.1 ENST00000511982.1	IL7R	interleukin 7 receptor
chr11_+_101983176	1.46	ENST00000524575.1	YAP1	Yes-associated protein 1
chr10_+_17270214	1.40	ENST00000544301.1	VIM	vimentin
chr7_-_80551671	1.38	ENST00000419255.2 ENST00000544525.1	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_+_10365404	1.26	ENST00000266458.5 ENST00000421801.2 ENST00000544284.1 ENST00000545047.1 ENST00000543602.1 ENST00000545887.1	GABARAPL1	GABA(A) receptor-associated protein like 1
chr16_+_15596123	1.23	ENST00000452191.2	C16orf45	chromosome 16 open reading frame 45
chr3_-_149293990	1.14	ENST00000472417.1	WWTR1	WW domain containing transcription regulator 1
chr3_-_114343768	1.14	ENST00000393785.2	ZBTB20	zinc finger and BTB domain containing 20
chr9_-_35112376	1.13	ENST00000488109.2	FAM214B	family with sequence similarity 214, member B
chr7_+_55177416	1.10	ENST00000450046.1 ENST00000454757.2	EGFR	epidermal growth factor receptor
chr8_+_70404996	1.05	ENST00000402687.4 ENST00000419716.3	SULF1	sulfatase 1
chr7_+_48128194	1.00	ENST00000416681.1 ENST00000331803.4 ENST00000432131.1	UPP1	uridine phosphorylase 1
chr7_+_48128316	0.99	ENST00000341253.4	UPP1	uridine phosphorylase 1
chr9_-_21335356	0.96	ENST00000359039.4	KLHL9	kelch-like family member 9
chr10_+_121410882	0.90	ENST00000369085.3	BAG3	BCL2-associated athanogene 3
chr17_-_33760269	0.87	ENST00000452764.3	SLFN12	schlafen family member 12
chr1_+_223889285	0.86	ENST00000433674.2	CAPN2	calpain 2, (m/II) large subunit
chr9_-_21335240	0.81	ENST00000537938.1	KLHL9	kelch-like family member 9
chr3_+_69134124	0.81	ENST00000478935.1	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr8_-_82395461	0.76	ENST00000256104.4	FABP4	fatty acid binding protein 4, adipocyte
chr15_+_22892663	0.74	ENST00000313077.7 ENST00000561274.1 ENST00000560848.1	CYFIP1	cytoplasmic FMR1 interacting protein 1
chr3_+_69134080	0.72	ENST00000273258.3	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr16_+_57662419	0.72	ENST00000388812.4 ENST00000538815.1 ENST00000456916.1 ENST00000567154.1 ENST00000388813.5 ENST00000562558.1 ENST00000566271.2	GPR56	G protein-coupled receptor 56
chr16_+_57662138	0.70	ENST00000562414.1 ENST00000561969.1 ENST00000562631.1 ENST00000563445.1 ENST00000565338.1 ENST00000567702.1	GPR56	G protein-coupled receptor 56
chr10_+_1102721	0.69	ENST00000263150.4	WDR37	WD repeat domain 37
chr20_+_4666882	0.68	ENST00000379440.4 ENST00000430350.2	PRNP	prion protein
chr6_-_56819385	0.66	ENST00000370754.5 ENST00000449297.2	DST	dystonin
chr4_+_74606223	0.65	ENST00000307407.3 ENST00000401931.1	IL8	interleukin 8
chr13_+_53602894	0.63	ENST00000219022.2	OLFM4	olfactomedin 4
chr15_-_60690163	0.62	ENST00000558998.1 ENST00000560165.1 ENST00000557986.1 ENST00000559780.1 ENST00000559467.1 ENST00000559956.1 ENST00000332680.4 ENST00000396024.3 ENST00000421017.2 ENST00000560466.1 ENST00000558132.1 ENST00000559113.1 ENST00000557906.1 ENST00000558558.1 ENST00000560468.1 ENST00000559370.1 ENST00000558169.1 ENST00000559725.1 ENST00000558985.1 ENST00000451270.2	ANXA2	annexin A2
chr3_-_18466787	0.59	ENST00000338745.6 ENST00000450898.1	SATB1	SATB homeobox 1
chrX_-_48901012	0.58	ENST00000315869.7	TFE3	transcription factor binding to IGHM enhancer 3
chr8_+_15397732	0.58	ENST00000382020.4 ENST00000506802.1 ENST00000509380.1 ENST00000503731.1	TUSC3	tumor suppressor candidate 3
chr2_-_145275228	0.57	ENST00000427902.1 ENST00000409487.3 ENST00000470879.1 ENST00000435831.1	ZEB2	zinc finger E-box binding homeobox 2
chr3_-_122512619	0.56	ENST00000383659.1 ENST00000306103.2	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr11_-_62323702	0.56	ENST00000530285.1	AHNAK	AHNAK nucleoprotein
chr7_+_23286182	0.56	ENST00000258733.4 ENST00000381990.2 ENST00000409458.3 ENST00000539136.1 ENST00000453162.2	GPNMB	glycoprotein (transmembrane) nmb
chr11_-_102401469	0.54	ENST00000260227.4	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)
chr1_+_26606608	0.53	ENST00000319041.6	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chrX_-_15288154	0.50	ENST00000380483.3 ENST00000380485.3 ENST00000380488.4	ASB9	ankyrin repeat and SOCS box containing 9
chr7_+_872107	0.49	ENST00000405266.1 ENST00000401592.1 ENST00000403868.1 ENST00000425407.2	SUN1	Sad1 and UNC84 domain containing 1
chr22_+_39916558	0.47	ENST00000337304.2 ENST00000396680.1	ATF4	activating transcription factor 4
chr3_-_18466026	0.47	ENST00000417717.2	SATB1	SATB homeobox 1
chr17_+_35851570	0.46	ENST00000394386.1	DUSP14	dual specificity phosphatase 14
chr1_+_156084461	0.44	ENST00000347559.2 ENST00000361308.4 ENST00000368300.4 ENST00000368299.3	LMNA	lamin A/C
chr16_+_89988259	0.41	ENST00000554444.1 ENST00000556565.1	TUBB3	Tubulin beta-3 chain
chr2_+_152214098	0.39	ENST00000243347.3	TNFAIP6	tumor necrosis factor, alpha-induced protein 6
chr1_-_160231451	0.38	ENST00000495887.1	DCAF8	DDB1 and CUL4 associated factor 8
chr19_-_46285646	0.37	ENST00000458663.2	DMPK	dystrophia myotonica-protein kinase
chr19_+_3366547	0.37	ENST00000341919.3 ENST00000590282.1 ENST00000443272.2	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr12_-_56101647	0.37	ENST00000347027.6 ENST00000257879.6 ENST00000257880.7 ENST00000394230.2 ENST00000394229.2	ITGA7	integrin, alpha 7
chr17_+_79650962	0.37	ENST00000329138.4	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_+_156096336	0.36	ENST00000504687.1 ENST00000473598.2	LMNA	lamin A/C
chr1_-_95007193	0.36	ENST00000370207.4 ENST00000334047.7	F3	coagulation factor III (thromboplastin, tissue factor)
chr4_+_169013666	0.32	ENST00000359299.3	ANXA10	annexin A10
chr21_-_36421535	0.32	ENST00000416754.1 ENST00000437180.1 ENST00000455571.1	RUNX1	runt-related transcription factor 1
chr6_-_84140757	0.32	ENST00000541327.1 ENST00000369705.3 ENST00000543031.1	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr5_+_179247759	0.31	ENST00000389805.4 ENST00000504627.1 ENST00000402874.3 ENST00000510187.1	SQSTM1	sequestosome 1
chr9_-_23826298	0.29	ENST00000380117.1	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr19_-_4455290	0.29	ENST00000394765.3 ENST00000592515.1	UBXN6	UBX domain protein 6
chr2_+_46926048	0.28	ENST00000306503.5	SOCS5	suppressor of cytokine signaling 5
chr21_-_36421626	0.28	ENST00000300305.3	RUNX1	runt-related transcription factor 1
chr11_-_66103867	0.28	ENST00000424433.2	RIN1	Ras and Rab interactor 1
chr8_-_141774467	0.26	ENST00000520151.1 ENST00000519024.1 ENST00000519465.1	PTK2	protein tyrosine kinase 2
chr17_+_75315534	0.26	ENST00000590294.1 ENST00000329047.8	SEPT9	septin 9
chr13_+_32838801	0.26	ENST00000542859.1	FRY	furry homolog (Drosophila)
chrX_+_153770421	0.25	ENST00000369609.5 ENST00000369607.1	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr12_+_57914742	0.25	ENST00000551351.1	MBD6	methyl-CpG binding domain protein 6
chr2_+_28615669	0.25	ENST00000379619.1 ENST00000264716.4	FOSL2	FOS-like antigen 2
chr11_-_75201791	0.25	ENST00000529721.1	GDPD5	glycerophosphodiester phosphodiesterase domain containing 5
chr4_+_120056939	0.24	ENST00000307128.5	MYOZ2	myozenin 2
chr12_-_57914275	0.22	ENST00000547303.1 ENST00000552740.1 ENST00000547526.1 ENST00000551116.1 ENST00000346473.3	DDIT3	DNA-damage-inducible transcript 3
chr19_-_45927622	0.22	ENST00000300853.3 ENST00000589165.1	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr5_-_138534071	0.22	ENST00000394817.2	SIL1	SIL1 nucleotide exchange factor
chr12_-_48152611	0.19	ENST00000389212.3	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_102826434	0.19	ENST00000340273.4 ENST00000260302.3	MMP13	matrix metallopeptidase 13 (collagenase 3)
chr19_+_13842559	0.17	ENST00000586600.1	CCDC130	coiled-coil domain containing 130
chr4_-_987217	0.17	ENST00000361661.2 ENST00000398516.2	SLC26A1	solute carrier family 26 (anion exchanger), member 1
chr21_-_36421401	0.16	ENST00000486278.2	RUNX1	runt-related transcription factor 1
chr19_-_5903714	0.16	ENST00000586349.1 ENST00000585661.1 ENST00000308961.4 ENST00000592634.1 ENST00000418389.2 ENST00000252675.5	AC024592.12 NDUFA11 FUT5	Uncharacterized protein NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr1_-_244006528	0.15	ENST00000336199.5 ENST00000263826.5	AKT3	v-akt murine thymoma viral oncogene homolog 3
chr5_+_72143988	0.15	ENST00000506351.2	TNPO1	transportin 1
chr17_-_73775839	0.15	ENST00000592643.1 ENST00000591890.1 ENST00000587171.1 ENST00000254810.4 ENST00000589599.1	H3F3B	H3 histone, family 3B (H3.3B)
chr5_-_149492904	0.14	ENST00000286301.3 ENST00000511344.1	CSF1R	colony stimulating factor 1 receptor
chr13_-_36429763	0.13	ENST00000379893.1	DCLK1	doublecortin-like kinase 1
chr11_-_102714534	0.13	ENST00000299855.5	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr5_-_148929848	0.12	ENST00000504676.1 ENST00000515435.1	CSNK1A1	casein kinase 1, alpha 1
chr6_+_63921351	0.12	ENST00000370659.1	FKBP1C	FK506 binding protein 1C
chrX_+_1734051	0.12	ENST00000381229.4 ENST00000381233.3	ASMT	acetylserotonin O-methyltransferase
chr12_+_6644443	0.12	ENST00000396858.1	GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr22_-_39715600	0.12	ENST00000427905.1 ENST00000402527.1 ENST00000216146.4	RPL3	ribosomal protein L3
chr9_+_118950325	0.11	ENST00000534838.1	PAPPA	pregnancy-associated plasma protein A, pappalysin 1
chr3_+_48507621	0.11	ENST00000456089.1	TREX1	three prime repair exonuclease 1
chrX_+_1733876	0.11	ENST00000381241.3	ASMT	acetylserotonin O-methyltransferase
chr1_+_213224572	0.11	ENST00000543470.1 ENST00000366960.3 ENST00000366959.3 ENST00000543354.1	RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr12_+_107168342	0.11	ENST00000392837.4	RIC8B	RIC8 guanine nucleotide exchange factor B
chr3_+_48507210	0.10	ENST00000433541.1 ENST00000422277.2 ENST00000436480.2 ENST00000444177.1	TREX1	three prime repair exonuclease 1
chr12_-_48152853	0.10	ENST00000171000.4	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr11_-_66103932	0.10	ENST00000311320.4	RIN1	Ras and Rab interactor 1
chr4_+_175839551	0.10	ENST00000404450.4 ENST00000514159.1	ADAM29	ADAM metallopeptidase domain 29
chr16_+_28996364	0.09	ENST00000564277.1	LAT	linker for activation of T cells
chr3_-_194090460	0.08	ENST00000428839.1 ENST00000347624.3	LRRC15	leucine rich repeat containing 15
chr12_+_107168418	0.08	ENST00000392839.2 ENST00000548914.1 ENST00000355478.2 ENST00000552619.1 ENST00000549643.1	RIC8B	RIC8 guanine nucleotide exchange factor B
chr9_+_140135665	0.08	ENST00000340384.4	TUBB4B	tubulin, beta 4B class IVb
chr12_+_52695617	0.07	ENST00000293525.5	KRT86	keratin 86
chr16_+_3692931	0.07	ENST00000407479.1	DNASE1	deoxyribonuclease I
chr20_-_17539456	0.06	ENST00000544874.1 ENST00000377868.2	BFSP1	beaded filament structural protein 1, filensin
chr17_-_53800217	0.06	ENST00000424486.2	TMEM100	transmembrane protein 100
chr11_-_82708519	0.06	ENST00000534301.1	RAB30	RAB30, member RAS oncogene family
chr20_+_30946106	0.05	ENST00000375687.4 ENST00000542461.1	ASXL1	additional sex combs like 1 (Drosophila)
chr1_-_45476944	0.05	ENST00000372172.4	HECTD3	HECT domain containing E3 ubiquitin protein ligase 3
chr9_-_74979420	0.05	ENST00000343431.2 ENST00000376956.3	ZFAND5	zinc finger, AN1-type domain 5
chr14_+_73525144	0.05	ENST00000261973.7 ENST00000540173.1	RBM25	RNA binding motif protein 25
chr17_-_47785504	0.05	ENST00000514907.1 ENST00000503334.1 ENST00000508520.1	SLC35B1	solute carrier family 35, member B1
chr4_-_122085469	0.05	ENST00000057513.3	TNIP3	TNFAIP3 interacting protein 3
chr4_+_3388057	0.05	ENST00000538395.1	RGS12	regulator of G-protein signaling 12
chr1_+_17634689	0.04	ENST00000375453.1 ENST00000375448.4	PADI4	peptidyl arginine deiminase, type IV
chr1_-_111148241	0.04	ENST00000440270.1	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2
chr19_+_50706866	0.04	ENST00000440075.2 ENST00000376970.2 ENST00000425460.1 ENST00000599920.1 ENST00000601313.1	MYH14	myosin, heavy chain 14, non-muscle
chr10_+_88428206	0.04	ENST00000429277.2 ENST00000458213.2 ENST00000352360.5	LDB3	LIM domain binding 3
chr17_+_66245341	0.04	ENST00000577985.1	AMZ2	archaelysin family metallopeptidase 2
chr17_+_48712206	0.04	ENST00000427699.1 ENST00000285238.8	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr6_-_161695042	0.04	ENST00000366908.5 ENST00000366911.5 ENST00000366905.3	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_+_27719148	0.04	ENST00000374024.3	GPR3	G protein-coupled receptor 3
chr1_-_93257951	0.03	ENST00000543509.1 ENST00000370331.1 ENST00000540033.1	EVI5	ecotropic viral integration site 5
chr18_+_21693306	0.03	ENST00000540918.2	TTC39C	tetratricopeptide repeat domain 39C
chr11_-_2924720	0.03	ENST00000455942.2	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense
chr12_-_10324716	0.02	ENST00000545927.1 ENST00000432556.2 ENST00000309539.3 ENST00000544577.1	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr16_+_31366455	0.02	ENST00000268296.4	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_+_154377669	0.01	ENST00000368485.3 ENST00000344086.4	IL6R	interleukin 6 receptor
chr16_+_28996416	0.01	ENST00000395456.2 ENST00000454369.2	LAT	linker for activation of T cells
chr17_+_74381343	0.01	ENST00000392496.3	SPHK1	sphingosine kinase 1
chr11_-_82708435	0.00	ENST00000525117.1 ENST00000532548.1	RAB30	RAB30, member RAS oncogene family
chr4_+_175839506	0.00	ENST00000505141.1 ENST00000359240.3 ENST00000445694.1	ADAM29	ADAM metallopeptidase domain 29
chr5_-_138533973	0.00	ENST00000507002.1 ENST00000505830.1 ENST00000508639.1 ENST00000265195.5	SIL1	SIL1 nucleotide exchange factor
chr7_-_55606346	0.00	ENST00000545390.1	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.1	3.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	4.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	4.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	3.2	PID AURORA B PATHWAY	Aurora B signaling
0.0	1.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	2.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	2.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	2.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	3.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0004850	uridine phosphorylase activity(GO:0004850)
0.5	1.5	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.3	1.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	1.4	GO:1990254	keratin filament binding(GO:1990254)
0.2	1.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	1.5	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	1.7	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	1.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	2.4	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	2.7	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.7	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	1.3	GO:0030957	Tat protein binding(GO:0030957)
0.1	0.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.4	GO:1903135	cupric ion binding(GO:1903135)
0.1	3.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.6	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.6	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	1.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.3	GO:0004473	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.2	GO:0051373	FATZ binding(GO:0051373)
0.0	2.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	1.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.7	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	4.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	2.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.2	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.6	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0019828	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.6	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.5	GO:0043495	protein anchor(GO:0043495)
0.0	0.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.3	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	3.5	GO:0044325	ion channel binding(GO:0044325)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	1.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0005459	UDP-galactose transmembrane transporter activity(GO:0005459)
0.0	0.1	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.6	GO:0005504	fatty acid binding(GO:0005504)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.0	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	1.7	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	3.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	2.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	3.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	3.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	3.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	1.7	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	2.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	1.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	2.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0006218	uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
0.4	2.4	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4	1.1	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3	1.7	GO:0009609	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.2	1.2	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.2	4.8	GO:0001765	membrane raft assembly(GO:0001765)
0.2	1.4	GO:0003350	pulmonary myocardium development(GO:0003350)
0.2	1.5	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.2	2.6	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2	0.7	GO:1903422	negative regulation of synaptic vesicle recycling(GO:1903422)
0.2	0.8	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2	0.5	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1	0.4	GO:1902938	regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1	1.7	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.6	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.1	2.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.1	3.4	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	1.5	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1	0.5	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1	0.4	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	1.1	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	4.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.1	1.5	GO:0070307	lens fiber cell development(GO:0070307)
0.1	2.2	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1	0.6	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.1	0.2	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.2	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.1	1.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1	0.7	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	0.3	GO:0030822	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1	0.6	GO:0015693	magnesium ion transport(GO:0015693)
0.1	0.3	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.1	1.1	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.3	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.3	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.2	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	1.5	GO:0019430	removal of superoxide radicals(GO:0019430)
0.0	0.1	GO:0035606	induction of programmed cell death(GO:0012502) peptidyl-cysteine S-trans-nitrosylation(GO:0035606) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.0	0.8	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.9	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.3	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0	0.2	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0	0.3	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.3	GO:0051964	netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.0	0.4	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.3	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) regulation of protein complex stability(GO:0061635)
0.0	1.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	1.3	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.7	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.5	GO:0044849	estrous cycle(GO:0044849)
0.0	0.4	GO:1903543	positive regulation of exosomal secretion(GO:1903543)
0.0	0.2	GO:0048505	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.4	GO:0016540	protein autoprocessing(GO:0016540)
0.0	2.5	GO:0002062	chondrocyte differentiation(GO:0002062)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.6	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.1	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.0	0.2	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.1	GO:0015785	UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0	0.1	GO:0038145	macrophage colony-stimulating factor signaling pathway(GO:0038145) cell-cell junction maintenance(GO:0045217)
0.0	0.4	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.0	0.0	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.2	GO:0042354	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.6	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4	1.1	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.3	1.5	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.2	2.2	GO:0097413	Lewy body(GO:0097413)
0.2	3.1	GO:0030478	actin cap(GO:0030478)
0.2	0.7	GO:0031673	H zone(GO:0031673)
0.2	2.4	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.6	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.1	0.4	GO:0033565	ESCRT-0 complex(GO:0033565)
0.1	0.7	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.7	GO:0044294	dendritic growth cone(GO:0044294)
0.1	0.8	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.1	1.1	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
0.0	1.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.1	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	0.3	GO:0044754	autolysosome(GO:0044754)
0.0	0.9	GO:0030018	Z disc(GO:0030018)
0.0	4.5	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	2.1	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.4	GO:0031307	nuclear outer membrane(GO:0005640) integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.4	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	3.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)