ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
JUND Links Ensembl NCBI GeneCards UniProt	ENSG00000130522.4	JUND

Gene	Promoter	Pearson corr. coef.	P-value	Plot
JUND	hg19_v2_chr19_-_18392422_18392440	0.56	2.3e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr12_-_8765446	4.25	ENST00000537228.1 ENST00000229335.6	AICDA	activation-induced cytidine deaminase
chr4_-_84035868	3.91	ENST00000426923.2 ENST00000509973.1	PLAC8	placenta-specific 8
chr4_-_84035905	3.82	ENST00000311507.4	PLAC8	placenta-specific 8
chr16_+_23847339	3.72	ENST00000303531.7	PRKCB	protein kinase C, beta
chr22_-_37545972	3.72	ENST00000216223.5	IL2RB	interleukin 2 receptor, beta
chr1_+_160709029	2.49	ENST00000444090.2 ENST00000441662.2	SLAMF7	SLAM family member 7
chrX_-_154563889	2.35	ENST00000369449.2 ENST00000321926.4	CLIC2	chloride intracellular channel 2
chr1_+_160709055	2.30	ENST00000368043.3 ENST00000368042.3 ENST00000458602.2 ENST00000458104.2	SLAMF7	SLAM family member 7
chr15_+_89181974	2.17	ENST00000306072.5	ISG20	interferon stimulated exonuclease gene 20kDa
chrX_+_78200829	2.12	ENST00000544091.1	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr12_+_7023491	1.96	ENST00000541477.1 ENST00000229277.1	ENO2	enolase 2 (gamma, neuronal)
chr22_+_23101182	1.95	ENST00000390312.2	IGLV2-14	immunoglobulin lambda variable 2-14
chr15_+_89182178	1.95	ENST00000559876.1	ISG20	interferon stimulated exonuclease gene 20kDa
chr15_+_89182156	1.94	ENST00000379224.5	ISG20	interferon stimulated exonuclease gene 20kDa
chr11_+_67250490	1.91	ENST00000528641.2 ENST00000279146.3	AIP	aryl hydrocarbon receptor interacting protein
chr18_-_74207146	1.87	ENST00000443185.2	ZNF516	zinc finger protein 516
chr21_+_42733870	1.74	ENST00000330714.3 ENST00000436410.1 ENST00000435611.1	MX2	myxovirus (influenza virus) resistance 2 (mouse)
chr1_+_223889310	1.65	ENST00000434648.1	CAPN2	calpain 2, (m/II) large subunit
chr11_-_2162162	1.62	ENST00000381389.1	IGF2	insulin-like growth factor 2 (somatomedin A)
chr3_-_105588231	1.58	ENST00000545639.1 ENST00000394027.3 ENST00000438603.1 ENST00000447441.1 ENST00000443752.1	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_54891495	1.28	ENST00000293373.6	NCKAP1L	NCK-associated protein 1-like
chr8_-_17752912	1.28	ENST00000398054.1 ENST00000381840.2	FGL1	fibrinogen-like 1
chr6_+_32146131	1.27	ENST00000375094.3	RNF5	ring finger protein 5, E3 ubiquitin protein ligase
chr14_-_23426270	1.17	ENST00000557591.1 ENST00000397409.4 ENST00000490506.1 ENST00000554406.1	HAUS4	HAUS augmin-like complex, subunit 4
chr14_-_23426337	1.16	ENST00000342454.8 ENST00000555986.1 ENST00000541587.1 ENST00000554516.1 ENST00000347758.2 ENST00000206474.7 ENST00000555040.1	HAUS4	HAUS augmin-like complex, subunit 4
chr8_-_17752996	1.16	ENST00000381841.2 ENST00000427924.1	FGL1	fibrinogen-like 1
chr14_-_23426322	1.15	ENST00000555367.1	HAUS4	HAUS augmin-like complex, subunit 4
chr11_-_2162468	1.13	ENST00000434045.2	IGF2	insulin-like growth factor 2 (somatomedin A)
chr3_-_98241760	1.11	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chrX_-_51797351	1.10	ENST00000375644.3	RP11-114H20.1	RP11-114H20.1
chr20_+_30946106	1.09	ENST00000375687.4 ENST00000542461.1	ASXL1	additional sex combs like 1 (Drosophila)
chrY_+_15016725	1.07	ENST00000336079.3	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chrX_+_51942963	0.96	ENST00000375625.3	RP11-363G10.2	RP11-363G10.2
chr15_+_75335604	0.93	ENST00000563393.1	PPCDC	phosphopantothenoylcysteine decarboxylase
chr15_+_59903975	0.91	ENST00000560585.1 ENST00000396065.1	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_207262881	0.89	ENST00000451804.2	C4BPB	complement component 4 binding protein, beta
chr19_+_35820064	0.87	ENST00000341773.6 ENST00000600131.1 ENST00000270311.6 ENST00000595780.1 ENST00000597916.1 ENST00000593867.1 ENST00000600424.1 ENST00000599811.1 ENST00000536635.2 ENST00000085219.5 ENST00000544992.2 ENST00000419549.2	CD22	CD22 molecule
chr17_+_41052808	0.87	ENST00000592383.1 ENST00000253801.2 ENST00000585489.1	G6PC	glucose-6-phosphatase, catalytic subunit
chr1_-_11918988	0.85	ENST00000376468.3	NPPB	natriuretic peptide B
chr4_-_100356291	0.81	ENST00000476959.1 ENST00000482593.1	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_76311791	0.81	ENST00000586321.1	AC061992.2	AC061992.2
chr12_-_102591604	0.78	ENST00000329406.4	PMCH	pro-melanin-concentrating hormone
chr21_-_43786634	0.77	ENST00000291527.2	TFF1	trefoil factor 1
chr7_+_33765593	0.74	ENST00000311067.3	RP11-89N17.1	HCG1643653; Uncharacterized protein
chr16_+_31366536	0.72	ENST00000562522.1	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_82708435	0.72	ENST00000525117.1 ENST00000532548.1	RAB30	RAB30, member RAS oncogene family
chr4_-_123542224	0.69	ENST00000264497.3	IL21	interleukin 21
chr8_-_27472198	0.68	ENST00000519472.1 ENST00000523589.1 ENST00000522413.1 ENST00000523396.1 ENST00000560366.1	CLU	clusterin
chr20_-_17539456	0.66	ENST00000544874.1 ENST00000377868.2	BFSP1	beaded filament structural protein 1, filensin
chr12_+_12938541	0.65	ENST00000356591.4	APOLD1	apolipoprotein L domain containing 1
chr6_-_44281043	0.64	ENST00000244571.4	AARS2	alanyl-tRNA synthetase 2, mitochondrial
chr1_-_54637997	0.61	ENST00000536061.1	AL357673.1	CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr18_-_19283649	0.58	ENST00000584464.1 ENST00000578270.1	ABHD3	abhydrolase domain containing 3
chr17_+_7590734	0.56	ENST00000457584.2	WRAP53	WD repeat containing, antisense to TP53
chr13_+_98605902	0.55	ENST00000460070.1 ENST00000481455.1 ENST00000261574.5 ENST00000493281.1 ENST00000463157.1 ENST00000471898.1 ENST00000489058.1 ENST00000481689.1	IPO5	importin 5
chr16_+_28996114	0.54	ENST00000395461.3	LAT	linker for activation of T cells
chr2_+_169926047	0.54	ENST00000428522.1 ENST00000450153.1 ENST00000421653.1	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr17_-_45899126	0.53	ENST00000007414.3 ENST00000392507.3	OSBPL7	oxysterol binding protein-like 7
chr4_-_100356551	0.53	ENST00000209665.4	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_43027105	0.53	ENST00000230413.5 ENST00000487429.1 ENST00000489623.1 ENST00000468957.1	MRPL2	mitochondrial ribosomal protein L2
chr6_+_44194762	0.50	ENST00000371708.1	SLC29A1	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr6_-_24936170	0.49	ENST00000538035.1	FAM65B	family with sequence similarity 65, member B
chr12_-_71182695	0.48	ENST00000342084.4	PTPRR	protein tyrosine phosphatase, receptor type, R
chr5_-_141061759	0.47	ENST00000508305.1	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr15_-_74504560	0.46	ENST00000449139.2	STRA6	stimulated by retinoic acid 6
chr4_-_104119528	0.46	ENST00000380026.3 ENST00000503705.1 ENST00000265148.3	CENPE	centromere protein E, 312kDa
chr11_-_5255696	0.44	ENST00000292901.3 ENST00000417377.1	HBD	hemoglobin, delta
chr11_-_82708519	0.44	ENST00000534301.1	RAB30	RAB30, member RAS oncogene family
chr17_+_25799008	0.43	ENST00000583370.1 ENST00000398988.3 ENST00000268763.6	KSR1	kinase suppressor of ras 1
chr5_-_141061777	0.42	ENST00000239440.4	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr19_+_13842559	0.41	ENST00000586600.1	CCDC130	coiled-coil domain containing 130
chr17_-_7590745	0.40	ENST00000514944.1 ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4	TP53	tumor protein p53
chr9_-_73029540	0.40	ENST00000377126.2	KLF9	Kruppel-like factor 9
chr20_-_62129163	0.40	ENST00000298049.7	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr16_-_67281413	0.38	ENST00000258201.4	FHOD1	formin homology 2 domain containing 1
chr16_+_19467772	0.37	ENST00000219821.5 ENST00000561503.1 ENST00000564959.1	TMC5	transmembrane channel-like 5
chr18_+_55888767	0.37	ENST00000431212.2 ENST00000586268.1 ENST00000587190.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chrX_+_99839799	0.37	ENST00000373031.4	TNMD	tenomodulin
chr14_+_73525229	0.36	ENST00000527432.1 ENST00000531500.1 ENST00000525321.1 ENST00000526754.1	RBM25	RNA binding motif protein 25
chr2_-_152830441	0.36	ENST00000534999.1 ENST00000397327.2	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr3_-_11762202	0.36	ENST00000445411.1 ENST00000404339.1 ENST00000273038.3	VGLL4	vestigial like 4 (Drosophila)
chr12_-_7818474	0.35	ENST00000229304.4	APOBEC1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr6_+_63921351	0.34	ENST00000370659.1	FKBP1C	FK506 binding protein 1C
chr14_+_58765103	0.34	ENST00000355431.3 ENST00000348476.3 ENST00000395168.3	ARID4A	AT rich interactive domain 4A (RBP1-like)
chr4_-_122085469	0.33	ENST00000057513.3	TNIP3	TNFAIP3 interacting protein 3
chr14_+_73525144	0.33	ENST00000261973.7 ENST00000540173.1	RBM25	RNA binding motif protein 25
chr13_-_31038370	0.33	ENST00000399489.1 ENST00000339872.4	HMGB1	high mobility group box 1
chr20_+_48429233	0.32	ENST00000417961.1	SLC9A8	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr15_-_74504597	0.32	ENST00000416286.3	STRA6	stimulated by retinoic acid 6
chr2_+_201980827	0.32	ENST00000309955.3 ENST00000443227.1 ENST00000341222.6 ENST00000355558.4 ENST00000340870.5 ENST00000341582.6	CFLAR	CASP8 and FADD-like apoptosis regulator
chr10_-_81708854	0.30	ENST00000372292.3	SFTPD	surfactant protein D
chr16_+_31366455	0.30	ENST00000268296.4	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_+_52695617	0.29	ENST00000293525.5	KRT86	keratin 86
chr3_+_155860751	0.29	ENST00000471742.1	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr20_+_48429356	0.29	ENST00000361573.2 ENST00000541138.1 ENST00000539601.1	SLC9A8	solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr10_+_18549645	0.26	ENST00000396576.2	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr2_-_152830479	0.26	ENST00000360283.6	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr1_+_236687881	0.26	ENST00000526634.1	LGALS8	lectin, galactoside-binding, soluble, 8
chr18_-_5419797	0.23	ENST00000542146.1 ENST00000427684.2	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr1_+_41204506	0.23	ENST00000525290.1 ENST00000530965.1 ENST00000416859.2 ENST00000308733.5	NFYC	nuclear transcription factor Y, gamma
chr8_+_128426535	0.21	ENST00000465342.2	POU5F1B	POU class 5 homeobox 1B
chr10_-_14996017	0.19	ENST00000378241.1 ENST00000456122.1 ENST00000418843.1 ENST00000378249.1 ENST00000396817.2 ENST00000378255.1 ENST00000378254.1 ENST00000378278.2 ENST00000357717.2	DCLRE1C	DNA cross-link repair 1C
chr18_+_32290218	0.17	ENST00000348997.5 ENST00000588949.1 ENST00000597599.1	DTNA	dystrobrevin, alpha
chr3_-_150996239	0.17	ENST00000309170.3	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr14_-_25103472	0.16	ENST00000216341.4 ENST00000382542.1 ENST00000382540.1	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_-_117753540	0.16	ENST00000328189.3 ENST00000369458.3	VTCN1	V-set domain containing T cell activation inhibitor 1
chr14_-_25103388	0.16	ENST00000526004.1 ENST00000415355.3	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_-_153513170	0.15	ENST00000368717.2	S100A5	S100 calcium binding protein A5
chr5_-_138533973	0.15	ENST00000507002.1 ENST00000505830.1 ENST00000508639.1 ENST00000265195.5	SIL1	SIL1 nucleotide exchange factor
chr17_+_30771279	0.15	ENST00000261712.3 ENST00000578213.1 ENST00000457654.2 ENST00000579451.1	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr10_-_14996070	0.13	ENST00000378258.1 ENST00000453695.2 ENST00000378246.2	DCLRE1C	DNA cross-link repair 1C
chr1_+_117297007	0.13	ENST00000369478.3 ENST00000369477.1	CD2	CD2 molecule
chr9_-_127263265	0.12	ENST00000373587.3	NR5A1	nuclear receptor subfamily 5, group A, member 1
chr11_-_4719072	0.12	ENST00000396950.3 ENST00000532598.1	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr10_+_5005598	0.11	ENST00000442997.1	AKR1C1	aldo-keto reductase family 1, member C1
chr14_+_73525265	0.10	ENST00000525161.1	RBM25	RNA binding motif protein 25
chr11_-_14913190	0.10	ENST00000532378.1	CYP2R1	cytochrome P450, family 2, subfamily R, polypeptide 1
chr22_-_39715600	0.10	ENST00000427905.1 ENST00000402527.1 ENST00000216146.4	RPL3	ribosomal protein L3
chr3_-_52713729	0.09	ENST00000296302.7 ENST00000356770.4 ENST00000337303.4 ENST00000409057.1 ENST00000410007.1 ENST00000409114.3 ENST00000409767.1 ENST00000423351.1	PBRM1	polybromo 1
chr1_+_213224572	0.08	ENST00000543470.1 ENST00000366960.3 ENST00000366959.3 ENST00000543354.1	RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr3_-_87325728	0.05	ENST00000350375.2	POU1F1	POU class 1 homeobox 1
chr19_+_11546093	0.05	ENST00000591462.1	PRKCSH	protein kinase C substrate 80K-H
chr16_-_72206034	0.05	ENST00000537465.1 ENST00000237353.10	PMFBP1	polyamine modulated factor 1 binding protein 1
chr13_+_109248500	0.05	ENST00000356711.2	MYO16	myosin XVI
chr3_-_46608010	0.05	ENST00000395905.3	LRRC2	leucine rich repeat containing 2
chr11_+_59856130	0.03	ENST00000278888.3	MS4A2	membrane-spanning 4-domains, subfamily A, member 2
chr19_-_54872556	0.02	ENST00000444687.1	LAIR1	leukocyte-associated immunoglobulin-like receptor 1
chr2_+_161993465	0.01	ENST00000457476.1	TANK	TRAF family member-associated NFKB activator
chr17_-_73150629	0.00	ENST00000356033.4 ENST00000405458.3 ENST00000409753.3	HN1	hematological and neurological expressed 1

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:0008859	exoribonuclease II activity(GO:0008859)
1.2	3.7	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.9	3.7	GO:0019976	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.7	4.6	GO:0004126	cytidine deaminase activity(GO:0004126)
0.3	1.3	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.3	2.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.3	0.9	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	0.9	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2	0.6	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	1.9	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.6	GO:0052740	1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1	2.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.5	GO:0043515	kinetochore binding(GO:0043515)
0.1	1.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	1.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.5	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	2.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.6	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	0.3	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	2.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.4	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.4	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.3	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.7	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0047023	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	1.6	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.8	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	1.3	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.5	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.6	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.9	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.5	GO:0015248	sterol transporter activity(GO:0015248)
0.0	1.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.4	3.5	GO:0070652	HAUS complex(GO:0070652)
0.3	2.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.2	2.4	GO:0005577	fibrinogen complex(GO:0005577)
0.2	4.3	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	1.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	6.6	GO:0015030	Cajal body(GO:0015030)
0.1	1.3	GO:0031209	SCAR complex(GO:0031209)
0.1	7.7	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.7	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.4	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.4	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	2.4	GO:0034707	chloride channel complex(GO:0034707)
0.0	2.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.3	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.4	GO:0032059	bleb(GO:0032059)
0.0	1.0	GO:0008305	integrin complex(GO:0008305)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	2.3	GO:0005643	nuclear pore(GO:0005643)
0.0	0.9	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.3	GO:0097342	ripoptosome(GO:0097342)
0.0	1.0	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.5	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.3	GO:0042599	lamellar body(GO:0042599)
0.0	0.4	GO:0005771	multivesicular body(GO:0005771)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.5	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	3.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	4.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	1.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	2.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.9	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.9	PID FOXO PATHWAY	FoxO family signaling
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	3.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	2.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	2.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	7.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	3.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.1	0.9	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.6	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	2.0	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.9	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.6	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.5	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	1.1	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.1	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
1.2	3.7	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.7	4.6	GO:0090308	regulation of methylation-dependent chromatin silencing(GO:0090308)
0.5	3.7	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.4	1.3	GO:0010430	fatty acid omega-oxidation(GO:0010430)
0.4	7.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.4	1.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.3	1.3	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.3	1.9	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3	2.8	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2	0.6	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.6	GO:0032203	telomere formation via telomerase(GO:0032203)
0.2	2.4	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2	1.7	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2	0.8	GO:0061143	alveolar primary septum development(GO:0061143)
0.1	0.4	GO:0051097	negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1	1.6	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.9	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.9	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	2.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.7	GO:0061517	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1	0.5	GO:0015862	uridine transport(GO:0015862)
0.1	0.9	GO:1903027	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1	0.4	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	0.3	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.1	0.3	GO:0002424	plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1	0.5	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	1.3	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.1	0.8	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	0.7	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1	0.5	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.1	0.3	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.4	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1	4.9	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	0.4	GO:0051414	response to cortisol(GO:0051414)
0.1	0.7	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.1	1.9	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.5	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.5	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.9	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0	0.1	GO:0007538	primary sex determination(GO:0007538)
0.0	0.2	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	2.0	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0	0.4	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.6	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0036378	calcitriol biosynthetic process from calciol(GO:0036378)
0.0	0.3	GO:1903944	negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.5	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.3	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.9	GO:0002385	mucosal immune response(GO:0002385)
0.0	3.5	GO:0051225	spindle assembly(GO:0051225)
0.0	0.3	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.0	0.4	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	1.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0	2.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.8	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.6	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.1	GO:0060133	somatotropin secreting cell development(GO:0060133)
0.0	1.0	GO:0034113	heterotypic cell-cell adhesion(GO:0034113)
0.0	0.6	GO:0006656	phosphatidylcholine biosynthetic process(GO:0006656)
0.0	0.3	GO:0034142	toll-like receptor 4 signaling pathway(GO:0034142)