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ENCODE cell lines, expression (Ernst 2011)

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Results for KLF7

Z-value: 0.32

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
KLF7
ENSG00000118263.10 KLF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208030647_208030689,
hg19_v2_chr2_-_208031943_208031991		-0.097.4e-01Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_96873921 0.40 ENST00000394166.3
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr19_-_39390440 0.31 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
 SIRT2
 sirtuin 2
chr19_-_39390350 0.29 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
 SIRT2
 sirtuin 2
chrX_-_92928557 0.25 ENST00000373079.3
ENST00000475430.2
 NAP1L3
 nucleosome assembly protein 1-like 3
chr1_-_21948906 0.18 ENST00000374761.2
ENST00000599760.1
 RAP1GAP
 RAP1 GTPase activating protein
chr7_+_27779714 0.17 ENST00000265393.6
ENST00000409980.1
ENST00000433216.2
ENST00000396319.2
 TAX1BP1
 Tax1 (human T-cell leukemia virus type I) binding protein 1
chr17_-_19281203 0.17 ENST00000487415.2
 B9D1
 B9 protein domain 1
chr6_+_31865552 0.17 ENST00000469372.1
ENST00000497706.1
 C2
 complement component 2
chr17_+_41476327 0.17 ENST00000320033.4
 ARL4D
 ADP-ribosylation factor-like 4D
chr1_-_19229248 0.16 ENST00000375341.3
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr19_-_14629224 0.16 ENST00000254322.2
 DNAJB1
 DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_188430478 0.16 ENST00000421427.1
 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_-_19229014 0.15 ENST00000538839.1
ENST00000290597.5
 ALDH4A1
 aldehyde dehydrogenase 4 family, member A1
chr6_-_33239612 0.15 ENST00000482399.1
ENST00000445902.2
 VPS52
 vacuolar protein sorting 52 homolog (S. cerevisiae)
chr5_+_141348598 0.15 ENST00000394520.2
ENST00000347642.3
 RNF14
 ring finger protein 14
chr6_-_33239712 0.15 ENST00000436044.2
 VPS52
 vacuolar protein sorting 52 homolog (S. cerevisiae)
chrX_+_102631844 0.14 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr19_+_39390587 0.14 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr5_+_141348721 0.13 ENST00000507163.1
ENST00000394519.1
 RNF14
 ring finger protein 14
chr19_+_39390320 0.12 ENST00000576510.1
 NFKBIB
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_+_30585486 0.10 ENST00000259873.4
ENST00000506373.2
 MRPS18B
 mitochondrial ribosomal protein S18B
chr16_+_31539183 0.08 ENST00000302312.4
 AHSP
 alpha hemoglobin stabilizing protein
chr3_-_33138624 0.06 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
 GLB1
 galactosidase, beta 1
chr16_+_31539197 0.05 ENST00000564707.1
 AHSP
 alpha hemoglobin stabilizing protein
chr20_+_2821340 0.05 ENST00000380445.3
ENST00000380469.3
 VPS16
 vacuolar protein sorting 16 homolog (S. cerevisiae)
chr1_-_21503337 0.05 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
 EIF4G3
 eukaryotic translation initiation factor 4 gamma, 3
chr17_+_38375574 0.04 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
 WIPF2
 WAS/WASL interacting protein family, member 2
chr9_+_130565487 0.04 ENST00000373225.3
ENST00000431857.1
 FPGS
 folylpolyglutamate synthase
chr17_+_73008755 0.03 ENST00000584208.1
ENST00000301585.5
 ICT1
 immature colon carcinoma transcript 1
chr9_+_130565147 0.03 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
 FPGS
 folylpolyglutamate synthase
chr8_-_6875778 0.03 ENST00000535841.1
ENST00000327857.2
 DEFA1B
DEFA3
 defensin, alpha 1B
defensin, alpha 3, neutrophil-specific
chr6_-_109703600 0.03 ENST00000512821.1
 CD164
 CD164 molecule, sialomucin
chr6_-_109703634 0.03 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
 CD164
 CD164 molecule, sialomucin
chr8_-_6837602 0.03 ENST00000382692.2
 DEFA1
 defensin, alpha 1
chr17_-_18218237 0.02 ENST00000542570.1
 TOP3A
 topoisomerase (DNA) III alpha
chr14_+_29234870 0.02 ENST00000382535.3
 FOXG1
 forkhead box G1
chr6_+_33239787 0.02 ENST00000439602.2
ENST00000474973.1
 RPS18
 ribosomal protein S18
chr19_-_7694417 0.02 ENST00000358368.4
ENST00000534844.1
 XAB2
 XPA binding protein 2
chr3_+_186353756 0.01 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
 FETUB
 fetuin B
chr13_-_108867101 0.01 ENST00000356922.4
 LIG4
 ligase IV, DNA, ATP-dependent
chr6_-_30585009 0.01 ENST00000376511.2
 PPP1R10
 protein phosphatase 1, regulatory subunit 10
chr1_-_155243235 0.01 ENST00000355560.4
ENST00000368361.4
 CLK2
 CDC-like kinase 2
chr1_-_157108266 0.00 ENST00000326786.4
 ETV3
 ets variant 3
chr22_-_30987837 0.00 ENST00000335214.6
 PES1
 pescadillo ribosomal biogenesis factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:2000777 positive regulation of oocyte maturation(GO:1900195) negative regulation of NLRP3 inflammasome complex assembly(GO:1900226) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)