ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
LEF1 Links Ensembl NCBI GeneCards UniProt	ENSG00000138795.5	LEF1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
LEF1	hg19_v2_chr4_-_109087872_109087881, hg19_v2_chr4_-_109088940_109089037	-0.34	1.9e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr10_+_54074033	4.00	ENST00000373970.3	DKK1	dickkopf WNT signaling pathway inhibitor 1
chr15_+_96869165	2.61	ENST00000421109.2	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr3_-_149375783	2.26	ENST00000467467.1 ENST00000460517.1 ENST00000360632.3	WWTR1	WW domain containing transcription regulator 1
chr7_+_16793160	2.06	ENST00000262067.4	TSPAN13	tetraspanin 13
chr12_-_6233828	1.77	ENST00000572068.1 ENST00000261405.5	VWF	von Willebrand factor
chr2_-_216257849	1.75	ENST00000456923.1	FN1	fibronectin 1
chr11_+_69455855	1.59	ENST00000227507.2 ENST00000536559.1	CCND1	cyclin D1
chr5_+_66124590	1.52	ENST00000490016.2 ENST00000403666.1 ENST00000450827.1	MAST4	microtubule associated serine/threonine kinase family member 4
chrX_+_15518923	1.52	ENST00000348343.6	BMX	BMX non-receptor tyrosine kinase
chr5_+_34757309	1.51	ENST00000397449.1	RAI14	retinoic acid induced 14
chr1_+_100111479	1.46	ENST00000263174.4	PALMD	palmdelphin
chr13_-_72440901	1.45	ENST00000359684.2	DACH1	dachshund homolog 1 (Drosophila)
chr11_+_114128522	1.41	ENST00000535401.1	NNMT	nicotinamide N-methyltransferase
chr1_+_93913713	1.41	ENST00000604705.1 ENST00000370253.2	FNBP1L	formin binding protein 1-like
chr13_-_110959478	1.36	ENST00000543140.1 ENST00000375820.4	COL4A1	collagen, type IV, alpha 1
chr14_-_21270995	1.32	ENST00000555698.1 ENST00000397970.4 ENST00000340900.3	RNASE1	ribonuclease, RNase A family, 1 (pancreatic)
chr1_+_100111580	1.32	ENST00000605497.1	PALMD	palmdelphin
chr3_-_134093395	1.32	ENST00000249883.5	AMOTL2	angiomotin like 2
chr4_-_186877502	1.31	ENST00000431902.1 ENST00000284776.7 ENST00000415274.1	SORBS2	sorbin and SH3 domain containing 2
chr2_-_1748214	1.31	ENST00000433670.1 ENST00000425171.1 ENST00000252804.4	PXDN	peroxidasin homolog (Drosophila)
chr3_-_169381183	1.20	ENST00000494292.1	MECOM	MDS1 and EVI1 complex locus
chr10_-_95241951	1.19	ENST00000358334.5 ENST00000359263.4 ENST00000371488.3	MYOF	myoferlin
chr10_-_95242044	1.18	ENST00000371501.4 ENST00000371502.4 ENST00000371489.1	MYOF	myoferlin
chr8_-_17579726	1.18	ENST00000381861.3	MTUS1	microtubule associated tumor suppressor 1
chr3_-_99569821	1.18	ENST00000487087.1	FILIP1L	filamin A interacting protein 1-like
chr13_-_72441315	1.14	ENST00000305425.4 ENST00000313174.7 ENST00000354591.4	DACH1	dachshund homolog 1 (Drosophila)
chr6_+_143929307	1.10	ENST00000427704.2 ENST00000305766.6	PHACTR2	phosphatase and actin regulator 2
chr3_+_173302222	1.08	ENST00000361589.4	NLGN1	neuroligin 1
chr5_-_16936340	1.08	ENST00000507288.1 ENST00000513610.1	MYO10	myosin X
chr3_-_134093275	1.06	ENST00000513145.1 ENST00000422605.2	AMOTL2	angiomotin like 2
chr20_-_23066953	1.06	ENST00000246006.4	CD93	CD93 molecule
chr9_+_504674	1.05	ENST00000382297.2	KANK1	KN motif and ankyrin repeat domains 1
chr18_+_3449821	1.04	ENST00000407501.2 ENST00000405385.3 ENST00000546979.1	TGIF1	TGFB-induced factor homeobox 1
chr7_-_27213893	1.01	ENST00000283921.4	HOXA10	homeobox A10
chr15_+_63335899	0.96	ENST00000561266.1	TPM1	tropomyosin 1 (alpha)
chr7_-_27224842	0.94	ENST00000517402.1	HOXA11	homeobox A11
chr18_-_25616519	0.94	ENST00000399380.3	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_157892498	0.89	ENST00000502773.1	PDGFC	platelet derived growth factor C
chr7_-_27224795	0.88	ENST00000006015.3	HOXA11	homeobox A11
chr12_+_6309963	0.87	ENST00000382515.2	CD9	CD9 molecule
chr7_-_27219849	0.86	ENST00000396344.4	HOXA10	homeobox A10
chr14_+_85996471	0.78	ENST00000330753.4	FLRT2	fibronectin leucine rich transmembrane protein 2
chr15_+_96873921	0.77	ENST00000394166.3	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr17_-_77924627	0.75	ENST00000572862.1 ENST00000573782.1 ENST00000574427.1 ENST00000570373.1 ENST00000340848.7 ENST00000576768.1	TBC1D16	TBC1 domain family, member 16
chr2_-_165424973	0.75	ENST00000543549.1	GRB14	growth factor receptor-bound protein 14
chr10_+_114710211	0.72	ENST00000349937.2 ENST00000369397.4	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr22_-_36357671	0.72	ENST00000408983.2	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr20_+_11898507	0.70	ENST00000378226.2	BTBD3	BTB (POZ) domain containing 3
chr1_-_12677714	0.70	ENST00000376223.2	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr17_-_46623441	0.70	ENST00000330070.4	HOXB2	homeobox B2
chr18_+_55888767	0.69	ENST00000431212.2 ENST00000586268.1 ENST00000587190.1	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr14_-_105444694	0.67	ENST00000333244.5	AHNAK2	AHNAK nucleoprotein 2
chr4_-_139163491	0.66	ENST00000280612.5	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr13_-_45150392	0.65	ENST00000501704.2	TSC22D1	TSC22 domain family, member 1
chr6_-_134639180	0.65	ENST00000367858.5	SGK1	serum/glucocorticoid regulated kinase 1
chr5_-_146833485	0.65	ENST00000398514.3	DPYSL3	dihydropyrimidinase-like 3
chr18_-_52989217	0.63	ENST00000570287.2	TCF4	transcription factor 4
chrX_-_10588459	0.63	ENST00000380782.2	MID1	midline 1 (Opitz/BBB syndrome)
chr1_-_225840747	0.62	ENST00000366843.2 ENST00000366844.3	ENAH	enabled homolog (Drosophila)
chr5_+_131593364	0.61	ENST00000253754.3 ENST00000379018.3	PDLIM4	PDZ and LIM domain 4
chr14_+_85996507	0.61	ENST00000554746.1	FLRT2	fibronectin leucine rich transmembrane protein 2
chr2_+_181845843	0.61	ENST00000602710.1	UBE2E3	ubiquitin-conjugating enzyme E2E 3
chr10_-_30024716	0.60	ENST00000375398.2 ENST00000375400.3	SVIL	supervillin
chr6_-_112575912	0.58	ENST00000522006.1 ENST00000230538.7 ENST00000519932.1	LAMA4	laminin, alpha 4
chr2_-_175629135	0.58	ENST00000409542.1 ENST00000409219.1	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr1_+_82266053	0.58	ENST00000370715.1 ENST00000370713.1 ENST00000319517.6 ENST00000370717.2 ENST00000394879.1 ENST00000271029.4 ENST00000335786.5	LPHN2	latrophilin 2
chr9_+_124088860	0.57	ENST00000373806.1	GSN	gelsolin
chr17_-_3571934	0.57	ENST00000225525.3	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chr10_+_123923205	0.57	ENST00000369004.3 ENST00000260733.3	TACC2	transforming, acidic coiled-coil containing protein 2
chr16_+_57673430	0.57	ENST00000540164.2 ENST00000568531.1	GPR56	G protein-coupled receptor 56
chrX_-_10588595	0.56	ENST00000423614.1 ENST00000317552.4	MID1	midline 1 (Opitz/BBB syndrome)
chr10_+_71561630	0.56	ENST00000398974.3 ENST00000398971.3 ENST00000398968.3 ENST00000398966.3 ENST00000398964.3 ENST00000398969.3 ENST00000356340.3 ENST00000398972.3 ENST00000398973.3	COL13A1	collagen, type XIII, alpha 1
chr11_-_6677018	0.55	ENST00000299441.3	DCHS1	dachsous cadherin-related 1
chr11_+_101983176	0.54	ENST00000524575.1	YAP1	Yes-associated protein 1
chr8_+_39770803	0.54	ENST00000518237.1	IDO1	indoleamine 2,3-dioxygenase 1
chr7_+_107224364	0.54	ENST00000491150.1	BCAP29	B-cell receptor-associated protein 29
chr10_-_69597915	0.54	ENST00000225171.2	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr18_-_53089723	0.53	ENST00000561992.1 ENST00000562512.2	TCF4	transcription factor 4
chr10_+_114709999	0.53	ENST00000355995.4 ENST00000545257.1 ENST00000543371.1 ENST00000536810.1 ENST00000355717.4 ENST00000538897.1 ENST00000534894.1	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_-_16900217	0.53	ENST00000441778.2	LDB2	LIM domain binding 2
chr4_-_16900410	0.52	ENST00000304523.5	LDB2	LIM domain binding 2
chr4_-_16900242	0.51	ENST00000502640.1 ENST00000506732.1	LDB2	LIM domain binding 2
chr4_-_16900184	0.51	ENST00000515064.1	LDB2	LIM domain binding 2
chr20_-_56284816	0.50	ENST00000395819.3 ENST00000341744.3	PMEPA1	prostate transmembrane protein, androgen induced 1
chr15_+_50474385	0.50	ENST00000267842.5	SLC27A2	solute carrier family 27 (fatty acid transporter), member 2
chr13_-_67802549	0.50	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr13_-_99630233	0.50	ENST00000376460.1 ENST00000442173.1	DOCK9	dedicator of cytokinesis 9
chr19_-_3028354	0.49	ENST00000586422.1	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr13_+_32605437	0.49	ENST00000380250.3	FRY	furry homolog (Drosophila)
chr4_+_20255123	0.48	ENST00000504154.1 ENST00000273739.5	SLIT2	slit homolog 2 (Drosophila)
chr12_+_79258547	0.48	ENST00000457153.2	SYT1	synaptotagmin I
chr1_+_196621002	0.46	ENST00000367429.4 ENST00000439155.2	CFH	complement factor H
chr19_-_6690723	0.46	ENST00000601008.1	C3	complement component 3
chr2_+_85360499	0.46	ENST00000282111.3	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
chr7_+_116312411	0.46	ENST00000456159.1 ENST00000397752.3 ENST00000318493.6	MET	met proto-oncogene
chr10_+_71561649	0.46	ENST00000398978.3 ENST00000354547.3 ENST00000357811.3	COL13A1	collagen, type XIII, alpha 1
chr1_+_66797687	0.45	ENST00000371045.5 ENST00000531025.1 ENST00000526197.1	PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_-_112575838	0.45	ENST00000455073.1	LAMA4	laminin, alpha 4
chr10_+_71561704	0.44	ENST00000520267.1	COL13A1	collagen, type XIII, alpha 1
chr9_+_103235365	0.44	ENST00000374879.4	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chrX_+_54835493	0.43	ENST00000396224.1	MAGED2	melanoma antigen family D, 2
chr10_-_69597810	0.43	ENST00000483798.2	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr17_-_46682321	0.43	ENST00000225648.3 ENST00000484302.2	HOXB6	homeobox B6
chr11_-_64013663	0.43	ENST00000392210.2	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr15_-_23932437	0.42	ENST00000331837.4	NDN	necdin, melanoma antigen (MAGE) family member
chr2_-_27592867	0.42	ENST00000451130.2	EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr4_-_85887503	0.41	ENST00000509172.1 ENST00000322366.6 ENST00000295888.4 ENST00000502713.1	WDFY3	WD repeat and FYVE domain containing 3
chr7_+_73868439	0.41	ENST00000424337.2	GTF2IRD1	GTF2I repeat domain containing 1
chr1_+_84630053	0.40	ENST00000394838.2 ENST00000370682.3 ENST00000432111.1	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr2_-_175629164	0.40	ENST00000409323.1 ENST00000261007.5 ENST00000348749.5	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr11_+_57529234	0.40	ENST00000360682.6 ENST00000361796.4 ENST00000529526.1 ENST00000426142.2 ENST00000399050.4 ENST00000361391.6 ENST00000361332.4 ENST00000532463.1 ENST00000529986.1 ENST00000358694.6 ENST00000532787.1 ENST00000533667.1 ENST00000532649.1 ENST00000528621.1 ENST00000530748.1 ENST00000428599.2 ENST00000527467.1 ENST00000528232.1 ENST00000531014.1 ENST00000526772.1 ENST00000529873.1 ENST00000525902.1 ENST00000532844.1 ENST00000526357.1 ENST00000530094.1 ENST00000415361.2 ENST00000532245.1 ENST00000534579.1 ENST00000526938.1	CTNND1	catenin (cadherin-associated protein), delta 1
chr4_+_146403912	0.39	ENST00000507367.1 ENST00000394092.2 ENST00000515385.1	SMAD1	SMAD family member 1
chr2_-_27593306	0.38	ENST00000347454.4	EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr3_-_58563094	0.38	ENST00000464064.1	FAM107A	family with sequence similarity 107, member A
chr16_+_68678892	0.36	ENST00000429102.2	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr2_-_27593180	0.36	ENST00000493344.2 ENST00000445933.2	EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr1_+_155036204	0.36	ENST00000368409.3 ENST00000359751.4 ENST00000427683.2 ENST00000556931.1 ENST00000505139.1	EFNA4 EFNA3 EFNA3	ephrin-A4 ephrin-A3 Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chrX_+_135229600	0.35	ENST00000370690.3	FHL1	four and a half LIM domains 1
chr5_-_176900610	0.35	ENST00000477391.2 ENST00000393565.1 ENST00000309007.5	DBN1	drebrin 1
chrX_-_10645773	0.34	ENST00000453318.2	MID1	midline 1 (Opitz/BBB syndrome)
chr11_-_75017734	0.34	ENST00000532525.1	ARRB1	arrestin, beta 1
chr4_-_111119804	0.34	ENST00000394607.3 ENST00000302274.3	ELOVL6	ELOVL fatty acid elongase 6
chr2_-_26205340	0.34	ENST00000264712.3	KIF3C	kinesin family member 3C
chr1_-_94079648	0.33	ENST00000370247.3	BCAR3	breast cancer anti-estrogen resistance 3
chrX_+_37545012	0.33	ENST00000378616.3	XK	X-linked Kx blood group (McLeod syndrome)
chr11_+_65408273	0.33	ENST00000394227.3	SIPA1	signal-induced proliferation-associated 1
chr2_+_234621551	0.32	ENST00000608381.1 ENST00000373414.3	UGT1A1 UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5
chr9_-_94186131	0.31	ENST00000297689.3	NFIL3	nuclear factor, interleukin 3 regulated
chr16_+_68678739	0.31	ENST00000264012.4	CDH3	cadherin 3, type 1, P-cadherin (placental)
chr1_-_95392635	0.31	ENST00000538964.1 ENST00000394202.4 ENST00000370206.4	CNN3	calponin 3, acidic
chr1_-_211752073	0.31	ENST00000367001.4	SLC30A1	solute carrier family 30 (zinc transporter), member 1
chr9_+_36036430	0.30	ENST00000377966.3	RECK	reversion-inducing-cysteine-rich protein with kazal motifs
chr10_+_114710425	0.30	ENST00000352065.5 ENST00000369395.1	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr18_+_29027696	0.30	ENST00000257189.4	DSG3	desmoglein 3
chr1_+_6845384	0.30	ENST00000303635.7	CAMTA1	calmodulin binding transcription activator 1
chrX_+_102631844	0.30	ENST00000372634.1 ENST00000299872.7	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_23037323	0.29	ENST00000544305.1 ENST00000374630.3 ENST00000400191.3 ENST00000374632.3	EPHB2	EPH receptor B2
chr11_+_65339820	0.29	ENST00000316409.2 ENST00000449319.2 ENST00000530349.1	FAM89B	family with sequence similarity 89, member B
chr7_-_27169801	0.29	ENST00000511914.1	HOXA4	homeobox A4
chr5_+_137514687	0.29	ENST00000394894.3	KIF20A	kinesin family member 20A
chr2_+_198669365	0.29	ENST00000428675.1	PLCL1	phospholipase C-like 1
chr19_-_3029011	0.28	ENST00000590536.1 ENST00000587137.1 ENST00000455444.2 ENST00000262953.6	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr9_-_23825956	0.28	ENST00000397312.2	ELAVL2	ELAV like neuron-specific RNA binding protein 2
chr3_+_52813932	0.28	ENST00000537050.1	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr5_+_137514834	0.28	ENST00000508792.1 ENST00000504621.1	KIF20A	kinesin family member 20A
chr1_+_196621156	0.28	ENST00000359637.2	CFH	complement factor H
chrX_+_51927919	0.27	ENST00000416960.1	MAGED4	melanoma antigen family D, 4
chr7_+_73868220	0.27	ENST00000455841.2	GTF2IRD1	GTF2I repeat domain containing 1
chr7_-_140178775	0.26	ENST00000474576.1 ENST00000473444.1 ENST00000471104.1	MKRN1	makorin ring finger protein 1
chr21_+_39628655	0.26	ENST00000398925.1 ENST00000398928.1 ENST00000328656.4 ENST00000443341.1	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr10_+_71562180	0.26	ENST00000517713.1 ENST00000522165.1 ENST00000520133.1	COL13A1	collagen, type XIII, alpha 1
chr5_+_92919043	0.26	ENST00000327111.3	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr10_-_32345305	0.26	ENST00000302418.4	KIF5B	kinesin family member 5B
chrX_+_135229559	0.26	ENST00000394155.2	FHL1	four and a half LIM domains 1
chr4_+_30721968	0.25	ENST00000361762.2	PCDH7	protocadherin 7
chr11_-_64013288	0.25	ENST00000542235.1	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_-_33686743	0.25	ENST00000333778.6 ENST00000539981.1	CLASP2	cytoplasmic linker associated protein 2
chr14_+_61201445	0.25	ENST00000261245.4 ENST00000539616.2	MNAT1	MNAT CDK-activating kinase assembly factor 1
chrX_-_39956656	0.25	ENST00000397354.3 ENST00000378444.4	BCOR	BCL6 corepressor
chrX_+_86772707	0.24	ENST00000373119.4	KLHL4	kelch-like family member 4
chr15_+_43985725	0.24	ENST00000413453.2	CKMT1A	creatine kinase, mitochondrial 1A
chr12_+_9067123	0.24	ENST00000543824.1	PHC1	polyhomeotic homolog 1 (Drosophila)
chr7_-_41742697	0.24	ENST00000242208.4	INHBA	inhibin, beta A
chr1_+_100818156	0.23	ENST00000336454.3	CDC14A	cell division cycle 14A
chr20_+_36149602	0.23	ENST00000062104.2 ENST00000346199.2	NNAT	neuronatin
chr12_+_117013656	0.23	ENST00000556529.1	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2
chr21_+_39628852	0.23	ENST00000398938.2	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_106641728	0.23	ENST00000378026.4	CKAP4	cytoskeleton-associated protein 4
chr6_-_32145861	0.23	ENST00000336984.6	AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1
chrX_+_86772787	0.23	ENST00000373114.4	KLHL4	kelch-like family member 4
chr15_-_48470558	0.23	ENST00000324324.7	MYEF2	myelin expression factor 2
chr6_+_32146131	0.22	ENST00000375094.3	RNF5	ring finger protein 5, E3 ubiquitin protein ligase
chr18_-_52989525	0.22	ENST00000457482.3	TCF4	transcription factor 4
chr17_-_62502022	0.22	ENST00000578804.1	DDX5	DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr4_+_113152881	0.22	ENST00000274000.5	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr3_-_171528227	0.22	ENST00000356327.5 ENST00000342215.6 ENST00000340989.4 ENST00000351298.4	PLD1	phospholipase D1, phosphatidylcholine-specific
chr1_-_109935819	0.22	ENST00000538502.1	SORT1	sortilin 1
chr6_-_112575758	0.21	ENST00000431543.2 ENST00000453937.2 ENST00000368638.4 ENST00000389463.4	LAMA4	laminin, alpha 4
chr15_+_40731920	0.21	ENST00000561234.1	BAHD1	bromo adjacent homology domain containing 1
chr11_+_120255997	0.21	ENST00000532993.1	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_68150744	0.21	ENST00000370986.4 ENST00000370985.3	GADD45A	growth arrest and DNA-damage-inducible, alpha
chrX_-_119694538	0.21	ENST00000371322.5	CUL4B	cullin 4B
chr12_+_81110684	0.20	ENST00000228644.3	MYF5	myogenic factor 5
chr4_+_113152978	0.20	ENST00000309703.6	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr7_-_102985035	0.20	ENST00000426036.2 ENST00000249270.7 ENST00000454277.1 ENST00000412522.1	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr16_+_89989687	0.20	ENST00000315491.7 ENST00000555576.1 ENST00000554336.1 ENST00000553967.1	TUBB3	Tubulin beta-3 chain
chr12_-_108154925	0.20	ENST00000228437.5	PRDM4	PR domain containing 4
chr12_+_53491220	0.20	ENST00000548547.1 ENST00000301464.3	IGFBP6	insulin-like growth factor binding protein 6
chr12_-_54691668	0.20	ENST00000553198.1	NFE2	nuclear factor, erythroid 2
chr10_+_97803151	0.20	ENST00000403870.3 ENST00000265992.5 ENST00000465148.2 ENST00000534974.1	CCNJ	cyclin J
chr19_-_18717627	0.20	ENST00000392386.3	CRLF1	cytokine receptor-like factor 1
chr3_+_6902794	0.19	ENST00000357716.4 ENST00000486284.1 ENST00000389336.4 ENST00000403881.1 ENST00000402647.2	GRM7	glutamate receptor, metabotropic 7
chr12_-_95611149	0.19	ENST00000549499.1 ENST00000343958.4 ENST00000546711.1	FGD6	FYVE, RhoGEF and PH domain containing 6
chr2_-_161056762	0.19	ENST00000428609.2 ENST00000409967.2	ITGB6	integrin, beta 6
chr1_-_244006528	0.19	ENST00000336199.5 ENST00000263826.5	AKT3	v-akt murine thymoma viral oncogene homolog 3
chr17_-_56065484	0.19	ENST00000581208.1	VEZF1	vascular endothelial zinc finger 1
chr2_-_100987007	0.19	ENST00000595083.1	AC012493.2	Uncharacterized protein
chr9_+_71820057	0.19	ENST00000539225.1	TJP2	tight junction protein 2
chr7_-_47621736	0.19	ENST00000311160.9	TNS3	tensin 3
chr16_-_30798492	0.19	ENST00000262525.4	ZNF629	zinc finger protein 629

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	2.9	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	3.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.9	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	3.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.9	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.4	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.7	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	1.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.0	PID FOXO PATHWAY	FoxO family signaling
0.0	2.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.7	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	4.0	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.8	3.4	GO:0009956	radial pattern formation(GO:0009956)
0.6	1.8	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.4	2.0	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.4	1.1	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3	1.4	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.3	2.6	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3	1.7	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3	0.8	GO:0032773	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.3	3.0	GO:0001778	plasma membrane repair(GO:0001778)
0.2	1.4	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.2	2.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.2	1.5	GO:0001865	NK T cell differentiation(GO:0001865)
0.2	0.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	0.7	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	1.6	GO:0070141	response to UV-A(GO:0070141)
0.2	0.5	GO:0021966	corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.2	0.5	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2	1.1	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2	0.5	GO:0001798	positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1	1.2	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.1	0.4	GO:0048203	vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1	0.7	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.1	0.5	GO:0036269	swimming behavior(GO:0036269)
0.1	1.8	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.1	0.5	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
0.1	1.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.7	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	1.0	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	1.5	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.4	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.3	GO:0021569	rhombomere 3 development(GO:0021569)
0.1	0.5	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1	0.6	GO:0044855	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1	0.3	GO:0031133	regulation of axon diameter(GO:0031133)
0.1	1.2	GO:0009414	response to water deprivation(GO:0009414)
0.1	0.4	GO:0035973	aggrephagy(GO:0035973)
0.1	0.2	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.1	0.4	GO:0097338	response to clozapine(GO:0097338)
0.1	0.2	GO:0060278	negative regulation of B cell differentiation(GO:0045578) regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1	0.3	GO:1902544	oxidative DNA demethylation(GO:0035511) regulation of DNA N-glycosylase activity(GO:1902544)
0.1	1.8	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	0.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.1	2.1	GO:0010669	epithelial structure maintenance(GO:0010669)
0.1	0.3	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1	0.4	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.1	1.5	GO:0097320	membrane tubulation(GO:0097320)
0.1	0.4	GO:0051013	microtubule severing(GO:0051013)
0.1	0.2	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.3	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	2.9	GO:0035329	hippo signaling(GO:0035329)
0.1	0.5	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	0.3	GO:0007070	negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1	0.3	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.4	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.5	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.4	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.1	1.5	GO:0060065	uterus development(GO:0060065)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.3	GO:0035617	stress granule disassembly(GO:0035617)
0.1	0.2	GO:0048687	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1	0.4	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1	0.5	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.4	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.4	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.6	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.2	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.2	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0	0.1	GO:1900158	positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0	0.6	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	1.3	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.3	GO:1904783	positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0	0.7	GO:0042325	regulation of phosphorylation(GO:0042325)
0.0	0.2	GO:1901377	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0	0.3	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.9	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.0	1.3	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	1.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.4	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.3	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684)
0.0	0.4	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.6	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.2	GO:0035881	amacrine cell differentiation(GO:0035881)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922) B cell proliferation involved in immune response(GO:0002322)
0.0	0.1	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.1	GO:1990637	response to prolactin(GO:1990637)
0.0	0.1	GO:1903028	positive regulation of opsonization(GO:1903028)
0.0	0.6	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.2	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.5	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	1.8	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.3	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.8	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.3	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.4	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0	1.3	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	1.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.2	GO:0048743	positive regulation of skeletal muscle fiber development(GO:0048743)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.3	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.0	0.4	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.8	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.2	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.7	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.2	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0	0.2	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.2	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.7	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.0	0.1	GO:2000288	positive regulation of myoblast proliferation(GO:2000288)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.1	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0	0.2	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0097368	histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:1990592	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0	0.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.3	1.7	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	1.4	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	1.8	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	1.2	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1	1.8	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.4	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.1	2.2	GO:0032433	filopodium tip(GO:0032433)
0.1	0.5	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	0.5	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.6	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.2	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1	0.8	GO:0016342	catenin complex(GO:0016342)
0.1	0.4	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.2	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	1.1	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279)
0.0	1.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0005915	zonula adherens(GO:0005915)
0.0	0.7	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.4	GO:0045180	basal cortex(GO:0045180)
0.0	1.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.3	GO:0060091	kinocilium(GO:0060091)
0.0	0.6	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0097422	tubular endosome(GO:0097422)
0.0	1.2	GO:0005605	basal lamina(GO:0005605)
0.0	4.5	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.4	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0005818	astral microtubule(GO:0000235) aster(GO:0005818)
0.0	3.7	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.6	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0030314	junctional membrane complex(GO:0030314)
0.0	4.0	GO:0043197	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0	2.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	9.0	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	2.2	GO:0005901	caveola(GO:0005901)
0.0	0.3	GO:0044295	axonal growth cone(GO:0044295)
0.0	0.5	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0061574	ASAP complex(GO:0061574)
0.0	0.4	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.9	GO:0030315	T-tubule(GO:0030315)
0.0	0.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.5	GO:0031941	filamentous actin(GO:0031941)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.5	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	1.0	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	1.1	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	2.3	GO:0030027	lamellipodium(GO:0030027)
0.0	0.0	GO:0018444	translation release factor complex(GO:0018444)
0.0	0.6	GO:0005771	multivesicular body(GO:0005771)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.5	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.5	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	2.0	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.0	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	1.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	1.2	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	2.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.4	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	1.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	1.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.3	GO:0048019	receptor antagonist activity(GO:0048019)
0.4	1.4	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2	1.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.2	2.1	GO:0030274	LIM domain binding(GO:0030274)
0.2	2.5	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2	0.5	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2	1.4	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.1	0.7	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	1.1	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	1.1	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	1.5	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1	0.3	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.1	0.3	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1	0.7	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.5	GO:0030348	syntaxin-3 binding(GO:0030348)
0.1	1.8	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	3.6	GO:0001972	retinoic acid binding(GO:0001972)
0.1	1.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.5	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.2	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	1.0	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.6	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.3	GO:0099609	microtubule lateral binding(GO:0099609)
0.1	1.8	GO:0019865	immunoglobulin binding(GO:0019865)
0.1	0.3	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1	3.3	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	1.4	GO:0070410	co-SMAD binding(GO:0070410)
0.0	1.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.6	GO:0045159	myosin II binding(GO:0045159)
0.0	0.9	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.4	GO:0004111	creatine kinase activity(GO:0004111)
0.0	1.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.5	GO:0004857	enzyme inhibitor activity(GO:0004857)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.0	1.0	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0038025	reelin receptor activity(GO:0038025)
0.0	0.4	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.2	GO:0035500	MH2 domain binding(GO:0035500)
0.0	0.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0	0.1	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0	0.2	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	1.8	GO:0016504	peptidase activator activity(GO:0016504)
0.0	0.2	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.0	0.2	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0	0.9	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.5	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.6	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.4	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.5	GO:0031005	filamin binding(GO:0031005)
0.0	1.2	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.3	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.9	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.2	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0005522	profilin binding(GO:0005522)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.0	0.7	GO:0003700	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.0	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.6	GO:0019894	kinesin binding(GO:0019894)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	1.8	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.9	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0050294	steroid sulfotransferase activity(GO:0050294)