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ENCODE cell lines, expression (Ernst 2011)

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Results for LHX3

Z-value: 1.10

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
LHX3
ENSG00000107187.11 LHX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3hg19_v2_chr9_-_139096955_139096979,
hg19_v2_chr9_-_139094988_139095012		-0.204.6e-01Click!

Activity profile of LHX3 motif

Sorted Z-values of LHX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_74301880 2.47 ENST00000395792.2
ENST00000226359.2
 AFP
 alpha-fetoprotein
chr17_-_39093672 2.33 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
 KRT23
 keratin 23 (histone deacetylase inducible)
chr17_-_64225508 1.98 ENST00000205948.6
 APOH
 apolipoprotein H (beta-2-glycoprotein I)
chr4_-_41884620 1.86 ENST00000504870.1
 LINC00682
 long intergenic non-protein coding RNA 682
chr16_-_28634874 1.83 ENST00000395609.1
ENST00000350842.4
 SULT1A1
 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_-_150208320 1.78 ENST00000534220.1
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_+_155484155 1.76 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr5_-_78809950 1.71 ENST00000334082.6
 HOMER1
 homer homolog 1 (Drosophila)
chr7_-_87342564 1.69 ENST00000265724.3
ENST00000416177.1
 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr16_+_15489603 1.46 ENST00000568766.1
ENST00000287594.7
 RP11-1021N1.1
MPV17L
 Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chrX_-_55057403 1.45 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
 ALAS2
 aminolevulinate, delta-, synthase 2
chr11_+_59824060 1.44 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_+_1674982 1.39 ENST00000572048.1
ENST00000573763.1
 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_+_59824127 1.37 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr5_-_1882858 1.32 ENST00000511126.1
ENST00000231357.2
 IRX4
 iroquois homeobox 4
chr4_+_155484103 1.26 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr1_-_24126023 1.15 ENST00000429356.1
 GALE
 UDP-galactose-4-epimerase
chr6_+_26104104 1.15 ENST00000377803.2
 HIST1H4C
 histone cluster 1, H4c
chr1_-_150208291 1.14 ENST00000533654.1
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_-_21566731 1.14 ENST00000360947.3
 ZNF219
 zinc finger protein 219
chr4_-_23891693 1.10 ENST00000264867.2
 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr2_-_166930131 1.09 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chr14_+_39583427 0.93 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
 GEMIN2
 gem (nuclear organelle) associated protein 2
chr12_+_49740700 0.86 ENST00000549441.2
ENST00000395069.3
 DNAJC22
 DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_-_150208363 0.85 ENST00000436748.2
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_10282742 0.85 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
 CLEC7A
 C-type lectin domain family 7, member A
chr3_+_157827841 0.84 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
 RSRC1
 arginine/serine-rich coiled-coil 1
chr4_-_185275104 0.83 ENST00000317596.3
 RP11-290F5.2
 RP11-290F5.2
chr3_+_63953415 0.80 ENST00000484332.1
 ATXN7
 ataxin 7
chr15_+_65843130 0.79 ENST00000569894.1
 PTPLAD1
 protein tyrosine phosphatase-like A domain containing 1
chrX_-_110655306 0.78 ENST00000371993.2
 DCX
 doublecortin
chr17_-_27418537 0.76 ENST00000408971.2
 TIAF1
 TGFB1-induced anti-apoptotic factor 1
chr3_-_141747950 0.75 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chrX_+_9431324 0.71 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
 TBL1X
 transducin (beta)-like 1X-linked
chr16_+_28565230 0.71 ENST00000317058.3
 CCDC101
 coiled-coil domain containing 101
chr17_-_60142609 0.70 ENST00000397786.2
 MED13
 mediator complex subunit 13
chr3_-_47517302 0.68 ENST00000441517.2
ENST00000545718.1
 SCAP
 SREBF chaperone
chr12_+_64798095 0.67 ENST00000332707.5
 XPOT
 exportin, tRNA
chr4_+_41937131 0.64 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
 TMEM33
 transmembrane protein 33
chr14_-_21567009 0.64 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
 ZNF219
 zinc finger protein 219
chr7_-_140482926 0.62 ENST00000496384.2
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chr5_+_59783540 0.61 ENST00000515734.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr3_-_141719195 0.60 ENST00000397991.4
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_158142750 0.57 ENST00000505888.1
ENST00000449365.1
 GRIA2
 glutamate receptor, ionotropic, AMPA 2
chr2_-_99279928 0.57 ENST00000414521.2
 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_72772462 0.57 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
 NAT9
 N-acetyltransferase 9 (GCN5-related, putative)
chr1_-_92952433 0.55 ENST00000294702.5
 GFI1
 growth factor independent 1 transcription repressor
chr2_+_234826016 0.55 ENST00000324695.4
ENST00000433712.2
 TRPM8
 transient receptor potential cation channel, subfamily M, member 8
chr19_+_48949030 0.53 ENST00000253237.5
 GRWD1
 glutamate-rich WD repeat containing 1
chr11_-_128894053 0.53 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr3_+_69812877 0.51 ENST00000457080.1
ENST00000328528.6
 MITF
 microphthalmia-associated transcription factor
chrX_+_107288197 0.50 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr1_-_150208412 0.49 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
 ANP32E
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_+_158141899 0.49 ENST00000264426.9
ENST00000506284.1
 GRIA2
 glutamate receptor, ionotropic, AMPA 2
chr16_+_89334512 0.49 ENST00000602042.1
 AC137932.1
 AC137932.1
chr18_+_72201829 0.49 ENST00000582365.1
 CNDP1
 carnosine dipeptidase 1 (metallopeptidase M20 family)
chr12_-_53994805 0.48 ENST00000328463.7
 ATF7
 activating transcription factor 7
chr17_-_10372875 0.47 ENST00000255381.2
 MYH4
 myosin, heavy chain 4, skeletal muscle
chr8_-_57123815 0.44 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1
 pleiomorphic adenoma gene 1
chr9_-_100000957 0.42 ENST00000366109.2
ENST00000607322.1
 RP11-498P14.5
 RP11-498P14.5
chr19_-_43969796 0.42 ENST00000244333.3
 LYPD3
 LY6/PLAUR domain containing 3
chr8_+_105352050 0.40 ENST00000297581.2
 DCSTAMP
 dendrocyte expressed seven transmembrane protein
chr12_-_10282836 0.38 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
 CLEC7A
 C-type lectin domain family 7, member A
chr5_+_59783941 0.38 ENST00000506884.1
ENST00000504876.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr12_+_4385230 0.37 ENST00000536537.1
 CCND2
 cyclin D2
chr10_-_115904361 0.35 ENST00000428953.1
ENST00000543782.1
 C10orf118
 chromosome 10 open reading frame 118
chr19_-_49149553 0.34 ENST00000084798.4
 CA11
 carbonic anhydrase XI
chr5_-_39274617 0.33 ENST00000510188.1
 FYB
 FYN binding protein
chr7_+_39017504 0.32 ENST00000403058.1
 POU6F2
 POU class 6 homeobox 2
chr4_+_113568207 0.32 ENST00000511529.1
 LARP7
 La ribonucleoprotein domain family, member 7
chr1_+_168250194 0.32 ENST00000367821.3
 TBX19
 T-box 19
chrX_+_24167746 0.31 ENST00000428571.1
ENST00000539115.1
 ZFX
 zinc finger protein, X-linked
chr4_+_158141843 0.30 ENST00000509417.1
ENST00000296526.7
 GRIA2
 glutamate receptor, ionotropic, AMPA 2
chr12_-_86650045 0.29 ENST00000604798.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr19_-_51920952 0.28 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
 SIGLEC10
 sialic acid binding Ig-like lectin 10
chr12_-_86650077 0.28 ENST00000552808.2
ENST00000547225.1
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr5_+_67586465 0.27 ENST00000336483.5
 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_107288239 0.27 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr14_-_36990354 0.26 ENST00000518149.1
 NKX2-1
 NK2 homeobox 1
chrX_+_108779004 0.26 ENST00000218004.1
 NXT2
 nuclear transport factor 2-like export factor 2
chr17_-_39623681 0.26 ENST00000225899.3
 KRT32
 keratin 32
chr12_-_52761262 0.24 ENST00000257901.3
 KRT85
 keratin 85
chrX_+_84258832 0.24 ENST00000373173.2
 APOOL
 apolipoprotein O-like
chr7_-_25268104 0.24 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr7_+_97361388 0.23 ENST00000350485.4
ENST00000346867.4
 TAC1
 tachykinin, precursor 1
chr17_-_8263538 0.23 ENST00000535173.1
 AC135178.1
 HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr20_+_30063067 0.22 ENST00000201979.2
 REM1
 RAS (RAD and GEM)-like GTP-binding 1
chr14_-_101295407 0.21 ENST00000596284.1
 AL117190.2
 AL117190.2
chr3_+_138340049 0.20 ENST00000464668.1
 FAIM
 Fas apoptotic inhibitory molecule
chr1_-_160549235 0.18 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
 CD84
 CD84 molecule
chr8_-_25281747 0.18 ENST00000421054.2
 GNRH1
 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr9_-_128246769 0.17 ENST00000444226.1
 MAPKAP1
 mitogen-activated protein kinase associated protein 1
chr2_-_228582709 0.16 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
 SLC19A3
 solute carrier family 19 (thiamine transporter), member 3
chr19_-_6279932 0.16 ENST00000252674.7
 MLLT1
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr1_-_45988542 0.15 ENST00000424390.1
 PRDX1
 peroxiredoxin 1
chr19_+_49199209 0.15 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
 FUT2
 fucosyltransferase 2 (secretor status included)
chr8_+_119294456 0.14 ENST00000366457.2
 AC023590.1
 Uncharacterized protein
chr17_-_4938712 0.13 ENST00000254853.5
ENST00000424747.1
 SLC52A1
 solute carrier family 52 (riboflavin transporter), member 1
chr1_+_197237352 0.13 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
 CRB1
 crumbs homolog 1 (Drosophila)
chr12_-_42631529 0.12 ENST00000548917.1
 YAF2
 YY1 associated factor 2
chrX_+_24167828 0.11 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
 ZFX
 zinc finger protein, X-linked
chr1_+_115572415 0.11 ENST00000256592.1
 TSHB
 thyroid stimulating hormone, beta
chr5_-_88119580 0.10 ENST00000539796.1
 MEF2C
 myocyte enhancer factor 2C
chr4_-_120243545 0.10 ENST00000274024.3
 FABP2
 fatty acid binding protein 2, intestinal
chr6_+_72926145 0.09 ENST00000425662.2
ENST00000453976.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr3_-_167191814 0.09 ENST00000466903.1
ENST00000264677.4
 SERPINI2
 serpin peptidase inhibitor, clade I (pancpin), member 2
chr14_+_29241910 0.08 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
 C14orf23
 chromosome 14 open reading frame 23
chr15_+_75970672 0.07 ENST00000435356.1
 AC105020.1
 Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr13_-_70682590 0.06 ENST00000377844.4
 KLHL1
 kelch-like family member 1
chr18_+_616672 0.06 ENST00000338387.7
 CLUL1
 clusterin-like 1 (retinal)
chr5_+_140557371 0.05 ENST00000239444.2
 PCDHB8
 protocadherin beta 8
chr22_+_23487513 0.05 ENST00000263116.2
ENST00000341989.4
 RAB36
 RAB36, member RAS oncogene family
chr3_+_138340067 0.04 ENST00000479848.1
 FAIM
 Fas apoptotic inhibitory molecule
chr5_-_59783882 0.03 ENST00000505507.2
ENST00000502484.2
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr4_+_3344141 0.02 ENST00000306648.7
 RGS12
 regulator of G-protein signaling 12
chr11_+_5009424 0.01 ENST00000300762.1
 MMP26
 matrix metallopeptidase 26

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 1.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) regulation of progesterone biosynthetic process(GO:2000182)
0.4 1.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 3.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 1.7 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.2 0.6 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 0.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 2.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 2.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.5 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 0.3 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 1.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.2 GO:0019388 galactose catabolic process(GO:0019388)
0.1 4.3 GO:0043486 histone exchange(GO:0043486)
0.1 0.2 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.8 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.2 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 1.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 2.8 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:2000272 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) negative regulation of receptor activity(GO:2000272)
0.0 0.3 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.7 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.3 GO:0009798 axis specification(GO:0009798)
0.0 0.7 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 3.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 4.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.4 GO:0043203 axon hillock(GO:0043203)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.1 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.1 GO:0097440 apical dendrite(GO:0097440)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 2.8 GO:0005882 intermediate filament(GO:0005882)
0.0 2.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.4 2.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3 1.7 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.3 1.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.2 1.8 GO:0004969 histamine receptor activity(GO:0004969)
0.2 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 4.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 3.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling