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ENCODE cell lines, expression (Ernst 2011)

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Results for LHX6

Z-value: 1.17

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Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
LHX6
ENSG00000106852.11 LHX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg19_v2_chr9_-_124990680_124990719-0.601.3e-02Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_52535712 4.30 ENST00000216286.5
ENST00000541773.1
 NID2
 nidogen 2 (osteonidogen)
chr20_+_19867150 3.77 ENST00000255006.6
 RIN2
 Ras and Rab interactor 2
chr11_+_5710919 3.69 ENST00000379965.3
ENST00000425490.1
 TRIM22
 tripartite motif containing 22
chr6_-_167040731 3.31 ENST00000265678.4
 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_55512742 2.85 ENST00000568715.1
ENST00000219070.4
 MMP2
 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_-_102668879 2.55 ENST00000315274.6
 MMP1
 matrix metallopeptidase 1 (interstitial collagenase)
chr3_-_149095652 2.53 ENST00000305366.3
 TM4SF1
 transmembrane 4 L six family member 1
chr3_-_99569821 2.48 ENST00000487087.1
 FILIP1L
 filamin A interacting protein 1-like
chr12_-_91546926 1.87 ENST00000550758.1
 DCN
 decorin
chr10_+_13141441 1.66 ENST00000263036.5
 OPTN
 optineurin
chr21_+_35014783 1.51 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
 ITSN1
 intersectin 1 (SH3 domain protein)
chr10_+_13141585 1.49 ENST00000378764.2
 OPTN
 optineurin
chr5_-_54830871 1.49 ENST00000307259.8
 PPAP2A
 phosphatidic acid phosphatase type 2A
chr1_+_81771806 1.43 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
 LPHN2
 latrophilin 2
chr12_-_102455902 1.42 ENST00000240079.6
 CCDC53
 coiled-coil domain containing 53
chr5_-_54830784 1.40 ENST00000264775.5
 PPAP2A
 phosphatidic acid phosphatase type 2A
chr12_-_102455846 1.38 ENST00000545679.1
 CCDC53
 coiled-coil domain containing 53
chr1_-_236228417 1.37 ENST00000264187.6
 NID1
 nidogen 1
chr15_+_40697988 1.34 ENST00000487418.2
ENST00000479013.2
 IVD
 isovaleryl-CoA dehydrogenase
chr1_-_236228403 1.33 ENST00000366595.3
 NID1
 nidogen 1
chr6_+_30457244 1.27 ENST00000376630.4
 HLA-E
 major histocompatibility complex, class I, E
chr10_+_13142225 1.24 ENST00000378747.3
 OPTN
 optineurin
chr14_+_74034310 1.23 ENST00000538782.1
 ACOT2
 acyl-CoA thioesterase 2
chr2_+_220143989 1.23 ENST00000336576.5
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr14_+_104182105 1.20 ENST00000311141.2
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr13_+_37006421 1.19 ENST00000255465.4
 CCNA1
 cyclin A1
chr6_+_148663729 1.18 ENST00000367467.3
 SASH1
 SAM and SH3 domain containing 1
chr6_+_29691198 1.17 ENST00000440587.2
ENST00000434407.2
 HLA-F
 major histocompatibility complex, class I, F
chr14_+_104182061 1.17 ENST00000216602.6
 ZFYVE21
 zinc finger, FYVE domain containing 21
chr8_-_13134045 1.05 ENST00000512044.2
 DLC1
 deleted in liver cancer 1
chr13_+_37005967 1.04 ENST00000440264.1
ENST00000449823.1
 CCNA1
 cyclin A1
chr2_+_220144052 1.03 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
 DNAJB2
 DnaJ (Hsp40) homolog, subfamily B, member 2
chr13_+_37006398 1.03 ENST00000418263.1
 CCNA1
 cyclin A1
chr18_+_61143994 1.01 ENST00000382771.4
 SERPINB5
 serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr6_+_29691056 0.98 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
 HLA-F
 major histocompatibility complex, class I, F
chr12_-_21654479 0.96 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
 RECQL
 RecQ protein-like (DNA helicase Q1-like)
chr11_-_102651343 0.96 ENST00000279441.4
ENST00000539681.1
 MMP10
 matrix metallopeptidase 10 (stromelysin 2)
chr17_+_42148097 0.95 ENST00000269097.4
 G6PC3
 glucose 6 phosphatase, catalytic, 3
chr16_-_66584059 0.92 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
 TK2
 thymidine kinase 2, mitochondrial
chr12_+_21654714 0.89 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
 GOLT1B
 golgi transport 1B
chr11_+_77532233 0.89 ENST00000525409.1
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr3_-_105588231 0.89 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr11_+_76156045 0.87 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
 C11orf30
 chromosome 11 open reading frame 30
chr14_+_76127529 0.87 ENST00000556977.1
ENST00000557636.1
ENST00000286650.5
ENST00000298832.9
 TTLL5
 tubulin tyrosine ligase-like family, member 5
chr7_+_150929550 0.87 ENST00000482173.1
ENST00000495645.1
ENST00000035307.2
 CHPF2
 chondroitin polymerizing factor 2
chr7_-_86849883 0.86 ENST00000433078.1
 TMEM243
 transmembrane protein 243, mitochondrial
chr7_-_121784285 0.78 ENST00000417368.2
 AASS
 aminoadipate-semialdehyde synthase
chr14_-_76127519 0.76 ENST00000256319.6
 C14orf1
 chromosome 14 open reading frame 1
chr13_+_73632897 0.71 ENST00000377687.4
 KLF5
 Kruppel-like factor 5 (intestinal)
chr3_-_160823158 0.68 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_+_77532155 0.66 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
 AAMDC
 adipogenesis associated, Mth938 domain containing
chr19_-_14606900 0.62 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
 GIPC1
 GIPC PDZ domain containing family, member 1
chr3_-_151034734 0.62 ENST00000260843.4
 GPR87
 G protein-coupled receptor 87
chr10_+_71561649 0.61 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
 COL13A1
 collagen, type XIII, alpha 1
chr3_-_160823040 0.58 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr17_+_41476327 0.58 ENST00000320033.4
 ARL4D
 ADP-ribosylation factor-like 4D
chr16_-_66583701 0.52 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
 TK2
 thymidine kinase 2, mitochondrial
chr5_+_66300446 0.51 ENST00000261569.7
 MAST4
 microtubule associated serine/threonine kinase family member 4
chr2_+_242089833 0.50 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
 PPP1R7
 protein phosphatase 1, regulatory subunit 7
chr19_-_10121144 0.50 ENST00000264828.3
 COL5A3
 collagen, type V, alpha 3
chr2_-_55276320 0.50 ENST00000357376.3
 RTN4
 reticulon 4
chr17_+_72772621 0.49 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
 TMEM104
 transmembrane protein 104
chr5_+_174151536 0.49 ENST00000239243.6
ENST00000507785.1
 MSX2
 msh homeobox 2
chr10_+_71561630 0.49 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
 COL13A1
 collagen, type XIII, alpha 1
chr17_+_73452695 0.49 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
 KIAA0195
 KIAA0195
chr17_+_74733744 0.48 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
 MFSD11
 major facilitator superfamily domain containing 11
chr22_-_39190116 0.47 ENST00000406622.1
ENST00000216068.4
ENST00000406199.3
 SUN2
DNAL4
 Sad1 and UNC84 domain containing 2
dynein, axonemal, light chain 4
chr7_+_100210133 0.47 ENST00000393950.2
ENST00000424091.2
 MOSPD3
 motile sperm domain containing 3
chr6_-_110501200 0.46 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
 WASF1
 WAS protein family, member 1
chr6_-_32095968 0.46 ENST00000375203.3
ENST00000375201.4
 ATF6B
 activating transcription factor 6 beta
chr20_+_18488137 0.45 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
 SEC23B
 Sec23 homolog B (S. cerevisiae)
chr7_+_100209725 0.45 ENST00000223054.4
 MOSPD3
 motile sperm domain containing 3
chr4_+_74275057 0.43 ENST00000511370.1
 ALB
 albumin
chr1_-_48866517 0.43 ENST00000371841.1
 SPATA6
 spermatogenesis associated 6
chr22_+_41777927 0.43 ENST00000266304.4
 TEF
 thyrotrophic embryonic factor
chr7_-_99277610 0.42 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
 CYP3A5
 cytochrome P450, family 3, subfamily A, polypeptide 5
chr7_+_100209979 0.39 ENST00000493970.1
ENST00000379527.2
 MOSPD3
 motile sperm domain containing 3
chr6_-_33285505 0.39 ENST00000431845.2
 ZBTB22
 zinc finger and BTB domain containing 22
chr16_+_6533380 0.38 ENST00000552089.1
 RBFOX1
 RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_113558272 0.38 ENST00000509061.1
ENST00000508577.1
ENST00000513553.1
 LARP7
 La ribonucleoprotein domain family, member 7
chr17_-_7167279 0.38 ENST00000571932.2
 CLDN7
 claudin 7
chr11_-_76155618 0.37 ENST00000530759.1
 RP11-111M22.3
 RP11-111M22.3
chr1_+_151735431 0.37 ENST00000321531.5
ENST00000315067.8
 OAZ3
 ornithine decarboxylase antizyme 3
chr3_-_105587879 0.37 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_-_103749105 0.36 ENST00000394801.4
ENST00000394804.2
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr19_-_7694417 0.35 ENST00000358368.4
ENST00000534844.1
 XAB2
 XPA binding protein 2
chr2_-_74618964 0.35 ENST00000417090.1
ENST00000409868.1
 DCTN1
 dynactin 1
chr6_-_82957433 0.35 ENST00000306270.7
 IBTK
 inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr12_+_7013897 0.34 ENST00000007969.8
ENST00000323702.5
 LRRC23
 leucine rich repeat containing 23
chr2_-_74619152 0.33 ENST00000440727.1
ENST00000409240.1
 DCTN1
 dynactin 1
chr5_+_142149932 0.33 ENST00000274498.4
 ARHGAP26
 Rho GTPase activating protein 26
chr9_+_34646651 0.32 ENST00000378842.3
 GALT
 galactose-1-phosphate uridylyltransferase
chr11_-_76155700 0.32 ENST00000572035.1
 RP11-111M22.3
 RP11-111M22.3
chr12_-_110883346 0.30 ENST00000547365.1
 ARPC3
 actin related protein 2/3 complex, subunit 3, 21kDa
chr14_+_100842735 0.30 ENST00000554998.1
ENST00000402312.3
ENST00000335290.6
ENST00000554175.1
 WDR25
 WD repeat domain 25
chr1_+_44115814 0.29 ENST00000372396.3
 KDM4A
 lysine (K)-specific demethylase 4A
chr9_+_34646624 0.29 ENST00000450095.2
ENST00000556278.1
 GALT
GALT
 galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr6_-_49681235 0.28 ENST00000339139.4
 CRISP2
 cysteine-rich secretory protein 2
chr17_+_41323204 0.28 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
 NBR1
 neighbor of BRCA1 gene 1
chr11_-_18548426 0.28 ENST00000357193.3
ENST00000536719.1
 TSG101
 tumor susceptibility 101
chr17_+_73452545 0.28 ENST00000314256.7
 KIAA0195
 KIAA0195
chr7_-_36764142 0.27 ENST00000258749.5
ENST00000535891.1
 AOAH
 acyloxyacyl hydrolase (neutrophil)
chr20_+_35807449 0.27 ENST00000237530.6
 RPN2
 ribophorin II
chr15_-_77712477 0.27 ENST00000560626.2
 PEAK1
 pseudopodium-enriched atypical kinase 1
chr12_+_7014126 0.27 ENST00000415834.1
ENST00000436789.1
 LRRC23
 leucine rich repeat containing 23
chr4_-_103749313 0.27 ENST00000394803.5
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr14_-_99947168 0.26 ENST00000331768.5
 SETD3
 SET domain containing 3
chr5_-_82969405 0.26 ENST00000510978.1
 HAPLN1
 hyaluronan and proteoglycan link protein 1
chr1_-_43833628 0.26 ENST00000413844.2
ENST00000372458.3
 ELOVL1
 ELOVL fatty acid elongase 1
chr10_-_99447024 0.25 ENST00000370626.3
 AVPI1
 arginine vasopressin-induced 1
chr11_+_33061543 0.25 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
 TCP11L1
 t-complex 11, testis-specific-like 1
chr10_+_71561704 0.24 ENST00000520267.1
 COL13A1
 collagen, type XIII, alpha 1
chr20_+_35807512 0.24 ENST00000373622.5
 RPN2
 ribophorin II
chr16_+_6533729 0.24 ENST00000551752.1
 RBFOX1
 RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_121843985 0.23 ENST00000264808.3
ENST00000428209.2
ENST00000515109.1
ENST00000394435.2
 PRDM5
 PR domain containing 5
chr12_+_7014064 0.23 ENST00000443597.2
 LRRC23
 leucine rich repeat containing 23
chrY_+_14813160 0.23 ENST00000338981.3
 USP9Y
 ubiquitin specific peptidase 9, Y-linked
chr18_+_616672 0.22 ENST00000338387.7
 CLUL1
 clusterin-like 1 (retinal)
chr6_+_39760129 0.22 ENST00000274867.4
 DAAM2
 dishevelled associated activator of morphogenesis 2
chrX_+_100353153 0.22 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
 CENPI
 centromere protein I
chr7_+_142458507 0.22 ENST00000492062.1
 PRSS1
 protease, serine, 1 (trypsin 1)
chr11_+_17298297 0.22 ENST00000529010.1
 NUCB2
 nucleobindin 2
chr6_-_27880174 0.22 ENST00000303324.2
 OR2B2
 olfactory receptor, family 2, subfamily B, member 2
chr17_-_4871085 0.22 ENST00000575142.1
ENST00000206020.3
 SPAG7
 sperm associated antigen 7
chr3_+_40498783 0.21 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
 RPL14
 ribosomal protein L14
chr4_+_89513574 0.21 ENST00000402738.1
ENST00000431413.1
ENST00000422770.1
ENST00000407637.1
 HERC3
 HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_-_100842588 0.21 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
 WARS
 tryptophanyl-tRNA synthetase
chr14_+_22293618 0.21 ENST00000390432.2
 TRAV10
 T cell receptor alpha variable 10
chr3_+_172468505 0.20 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
 ECT2
 epithelial cell transforming sequence 2 oncogene
chr2_+_113763031 0.19 ENST00000259211.6
 IL36A
 interleukin 36, alpha
chr20_+_54967409 0.19 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
 CSTF1
 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr12_-_56753858 0.19 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
 STAT2
 signal transducer and activator of transcription 2, 113kDa
chr13_+_98086445 0.18 ENST00000245304.4
 RAP2A
 RAP2A, member of RAS oncogene family
chr12_+_27677085 0.18 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
 PPFIBP1
 PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr11_-_128894053 0.17 ENST00000392657.3
 ARHGAP32
 Rho GTPase activating protein 32
chr3_+_133292574 0.16 ENST00000264993.3
 CDV3
 CDV3 homolog (mouse)
chr10_-_104001231 0.16 ENST00000370002.3
 PITX3
 paired-like homeodomain 3
chr11_+_17298255 0.15 ENST00000531172.1
ENST00000533738.2
ENST00000323688.6
 NUCB2
 nucleobindin 2
chr4_+_113558612 0.15 ENST00000505034.1
ENST00000324052.6
 LARP7
 La ribonucleoprotein domain family, member 7
chr8_+_9413410 0.15 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
 TNKS
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_46626847 0.15 ENST00000242848.4
ENST00000282007.3
 ZC3H13
 zinc finger CCCH-type containing 13
chr5_+_142149955 0.15 ENST00000378004.3
 ARHGAP26
 Rho GTPase activating protein 26
chr3_+_172468472 0.14 ENST00000232458.5
ENST00000392692.3
 ECT2
 epithelial cell transforming sequence 2 oncogene
chr6_-_29396243 0.13 ENST00000377148.1
 OR11A1
 olfactory receptor, family 11, subfamily A, member 1
chr5_-_112630598 0.13 ENST00000302475.4
 MCC
 mutated in colorectal cancers
chr1_+_236958554 0.13 ENST00000366577.5
ENST00000418145.2
 MTR
 5-methyltetrahydrofolate-homocysteine methyltransferase
chr14_+_99947715 0.12 ENST00000389879.5
ENST00000557441.1
ENST00000555049.1
ENST00000555842.1
 CCNK
 cyclin K
chr9_+_71944241 0.12 ENST00000257515.8
 FAM189A2
 family with sequence similarity 189, member A2
chr9_-_95640218 0.12 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
 ZNF484
 zinc finger protein 484
chr12_-_9760482 0.11 ENST00000229402.3
 KLRB1
 killer cell lectin-like receptor subfamily B, member 1
chr12_-_10955226 0.10 ENST00000240687.2
 TAS2R7
 taste receptor, type 2, member 7
chr19_-_12833361 0.10 ENST00000592287.1
 TNPO2
 transportin 2
chr22_-_17640110 0.10 ENST00000399852.3
ENST00000336737.4
 CECR5
 cat eye syndrome chromosome region, candidate 5
chr7_-_72971934 0.10 ENST00000411832.1
 BCL7B
 B-cell CLL/lymphoma 7B
chr10_+_7830092 0.09 ENST00000356708.7
 ATP5C1
 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr3_+_158519654 0.09 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr19_-_19302931 0.09 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
 MEF2BNB-MEF2B
MEF2BNB
MEF2B
 MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr9_+_130565147 0.09 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
 FPGS
 folylpolyglutamate synthase
chr21_-_38639813 0.09 ENST00000309117.6
ENST00000398998.1
 DSCR3
 Down syndrome critical region gene 3
chr6_-_31125850 0.09 ENST00000507751.1
ENST00000448162.2
ENST00000502557.1
ENST00000503420.1
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.1
ENST00000396263.2
ENST00000508683.1
ENST00000428174.1
ENST00000448141.2
ENST00000507829.1
ENST00000455279.2
ENST00000376266.5
 CCHCR1
 coiled-coil alpha-helical rod protein 1
chr6_-_155776966 0.08 ENST00000159060.2
 NOX3
 NADPH oxidase 3
chr5_-_137878887 0.07 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
 ETF1
 eukaryotic translation termination factor 1
chr1_-_204380919 0.07 ENST00000367188.4
 PPP1R15B
 protein phosphatase 1, regulatory subunit 15B
chr1_+_28261621 0.07 ENST00000549094.1
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr6_+_26402465 0.07 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
 BTN3A1
 butyrophilin, subfamily 3, member A1
chr19_-_41870026 0.06 ENST00000243578.3
 B9D2
 B9 protein domain 2
chr17_-_77770830 0.06 ENST00000269385.4
 CBX8
 chromobox homolog 8
chr7_-_87342564 0.06 ENST00000265724.3
ENST00000416177.1
 ABCB1
 ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr4_-_103748880 0.06 ENST00000453744.2
ENST00000349311.8
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr17_+_66511540 0.05 ENST00000588188.2
 PRKAR1A
 protein kinase, cAMP-dependent, regulatory, type I, alpha
chr22_-_42017021 0.05 ENST00000263256.6
 DESI1
 desumoylating isopeptidase 1
chr1_-_13390765 0.05 ENST00000357367.2
 PRAMEF8
 PRAME family member 8
chr5_-_94890648 0.05 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
 TTC37
 tetratricopeptide repeat domain 37
chr1_-_13673511 0.05 ENST00000344998.3
ENST00000334600.6
 PRAMEF14
 PRAME family member 14
chr6_+_29624758 0.04 ENST00000376917.3
ENST00000376902.3
ENST00000533330.2
ENST00000376888.2
 MOG
 myelin oligodendrocyte glycoprotein
chr11_+_67798114 0.04 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
 NDUFS8
 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr14_+_52456327 0.04 ENST00000556760.1
 C14orf166
 chromosome 14 open reading frame 166
chr22_+_42017459 0.04 ENST00000405878.1
 XRCC6
 X-ray repair complementing defective repair in Chinese hamster cells 6
chrX_+_113818545 0.04 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
 HTR2C
 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr6_-_62996066 0.04 ENST00000281156.4
 KHDRBS2
 KH domain containing, RNA binding, signal transduction associated 2
chr6_+_52051171 0.04 ENST00000340057.1
 IL17A
 interleukin 17A
chr5_-_137548997 0.04 ENST00000505120.1
ENST00000394886.2
ENST00000394884.3
 CDC23
 cell division cycle 23
chr11_-_133826852 0.03 ENST00000533871.2
ENST00000321016.8
 IGSF9B
 immunoglobulin superfamily, member 9B
chr11_+_67798090 0.03 ENST00000313468.5
 NDUFS8
 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr10_-_48416849 0.03 ENST00000249598.1
 GDF2
 growth differentiation factor 2
chr6_-_29395509 0.02 ENST00000377147.2
 OR11A1
 olfactory receptor, family 11, subfamily A, member 1
chr17_-_40828969 0.02 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
 PLEKHH3
 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr17_-_41466555 0.02 ENST00000586231.1
 LINC00910
 long intergenic non-protein coding RNA 910
chr11_+_7110165 0.02 ENST00000306904.5
 RBMXL2
 RNA binding motif protein, X-linked-like 2
chr6_+_160542821 0.02 ENST00000366963.4
 SLC22A1
 solute carrier family 22 (organic cation transporter), member 1
chr22_+_42017280 0.01 ENST00000402580.3
ENST00000428575.2
ENST00000359308.4
 XRCC6
 X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_-_55866997 0.01 ENST00000360526.3
ENST00000361503.4
 CES1
 carboxylesterase 1
chr14_-_104181771 0.01 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
 XRCC3
 X-ray repair complementing defective repair in Chinese hamster cells 3
chr18_+_5238055 0.01 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
 LINC00667
 long intergenic non-protein coding RNA 667
chr1_+_28261492 0.01 ENST00000373894.3
 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
chr3_+_67705121 0.01 ENST00000464420.1
ENST00000482677.1
 RP11-81N13.1
 RP11-81N13.1
chr6_+_160542870 0.00 ENST00000324965.4
ENST00000457470.2
 SLC22A1
 solute carrier family 22 (organic cation transporter), member 1
chr12_-_95611149 0.00 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
 FGD6
 FYVE, RhoGEF and PH domain containing 6
chr19_+_12902289 0.00 ENST00000302754.4
 JUNB
 jun B proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.5 2.7 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 2.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.4 2.2 GO:0046979 TAP2 binding(GO:0046979)
0.3 0.9 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 0.9 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 4.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 1.0 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 6.7 GO:0005518 collagen binding(GO:0005518)
0.1 3.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 6.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 3.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 3.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 7.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 4.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 3.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.6 2.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.5 3.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.3 GO:0032679 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) protection from natural killer cell mediated cytotoxicity(GO:0042270) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.4 1.4 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 1.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.3 0.8 GO:0019477 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2 2.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 7.0 GO:0071711 basement membrane organization(GO:0071711)
0.2 0.6 GO:0006258 UDP-glucose catabolic process(GO:0006258) galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.5 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.2 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.8 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.3 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 3.3 GO:0007141 male meiosis I(GO:0007141)
0.1 0.9 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.7 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 2.5 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 3.5 GO:0070206 protein trimerization(GO:0070206)
0.1 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 2.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 1.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:1900113 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.9 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.3 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.5 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.4 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 1.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.3 3.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 4.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.7 GO:0005605 basal lamina(GO:0005605)
0.1 4.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 3.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 1.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 5.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs