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ENCODE cell lines, expression (Ernst 2011)

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Results for LHX8

Z-value: 0.79

Motif logo

Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
ENSG00000162624.10 LHX8

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_74275057 2.58 ENST00000511370.1
ALB
albumin
chr4_+_166300084 1.96 ENST00000402744.4
CPE
carboxypeptidase E
chr4_-_110723134 1.67 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr4_-_110723335 1.65 ENST00000394634.2
CFI
complement factor I
chr4_-_110723194 1.64 ENST00000394635.3
CFI
complement factor I
chr7_-_22234381 1.58 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr10_-_101825151 1.16 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr2_-_158345462 1.06 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr12_-_8043736 0.96 ENST00000539924.1
SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr1_+_70876926 0.71 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr12_-_8088871 0.70 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr2_+_201994208 0.67 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chrX_-_20236970 0.64 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_155484155 0.57 ENST00000509493.1
FGB
fibrinogen beta chain
chr9_-_5833027 0.56 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr7_+_74188309 0.55 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr8_-_82395461 0.55 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr7_+_142498725 0.54 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr7_-_137028498 0.51 ENST00000393083.2
PTN
pleiotrophin
chr3_+_173116225 0.50 ENST00000457714.1
NLGN1
neuroligin 1
chr12_-_15038779 0.48 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr7_-_137028534 0.46 ENST00000348225.2
PTN
pleiotrophin
chr3_-_57199397 0.46 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr10_+_94352956 0.41 ENST00000260731.3
KIF11
kinesin family member 11
chr2_+_201994042 0.41 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chrX_+_108779004 0.40 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chrX_+_84258832 0.39 ENST00000373173.2
APOOL
apolipoprotein O-like
chr4_+_155484103 0.39 ENST00000302068.4
FGB
fibrinogen beta chain
chr9_-_36276966 0.39 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr19_-_4535233 0.39 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr1_+_28696111 0.38 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr2_+_86947296 0.37 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr15_-_65426174 0.37 ENST00000204549.4
PDCD7
programmed cell death 7
chr9_-_20622478 0.36 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_-_123676827 0.36 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr4_-_83812402 0.33 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_-_88285309 0.33 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr7_+_55980331 0.32 ENST00000429591.2
ZNF713
zinc finger protein 713
chr4_+_68424434 0.31 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr1_-_212004090 0.31 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr3_-_119182523 0.30 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr4_-_186733363 0.30 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr4_-_83812248 0.30 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chr19_+_34855925 0.30 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr7_-_144435985 0.29 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr1_+_212208919 0.29 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_87144738 0.29 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr1_-_236445251 0.29 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr1_-_160492994 0.28 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr19_+_34855874 0.28 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr15_-_34880646 0.28 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr2_-_50201327 0.28 ENST00000412315.1
NRXN1
neurexin 1
chr2_-_152830441 0.28 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr5_+_175511859 0.27 ENST00000503724.2
ENST00000253490.4
FAM153B
family with sequence similarity 153, member B
chr14_+_39583427 0.27 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr22_-_29107919 0.26 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr12_+_9822331 0.25 ENST00000545918.1
ENST00000543300.1
ENST00000261339.6
ENST00000466035.2
CLEC2D
C-type lectin domain family 2, member D
chr2_-_136288113 0.25 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr2_+_87135076 0.25 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr20_+_34824355 0.24 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2
AAR2 splicing factor homolog (S. cerevisiae)
chr3_-_52804872 0.24 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4
NIMA-related kinase 4
chr19_+_12175504 0.23 ENST00000439326.3
ZNF844
zinc finger protein 844
chr2_-_152118352 0.23 ENST00000331426.5
RBM43
RNA binding motif protein 43
chrX_+_108779870 0.22 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr12_-_71551868 0.22 ENST00000247829.3
TSPAN8
tetraspanin 8
chr5_-_147162263 0.22 ENST00000333010.6
ENST00000265272.5
JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_+_58018269 0.21 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr2_-_136678123 0.20 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr22_-_50219548 0.20 ENST00000404034.1
BRD1
bromodomain containing 1
chr5_-_24645078 0.20 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr2_-_152830479 0.20 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr1_+_95616933 0.20 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chrX_+_73164149 0.19 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr14_+_23067146 0.19 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr11_-_72504637 0.19 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_-_225266743 0.19 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chr3_+_195447738 0.19 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr2_-_225266711 0.19 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr4_+_106631966 0.18 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr15_+_65843130 0.17 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr3_+_148545586 0.17 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr3_-_149470229 0.17 ENST00000473414.1
COMMD2
COMM domain containing 2
chr19_+_44716678 0.16 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
ZNF227
zinc finger protein 227
chr4_+_57302297 0.16 ENST00000399688.3
ENST00000512576.1
PAICS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr9_-_21166659 0.16 ENST00000380225.1
IFNA21
interferon, alpha 21
chr7_-_20256965 0.16 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr12_-_53893399 0.16 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr13_+_53216565 0.16 ENST00000357495.2
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr10_+_135207598 0.16 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr13_+_98605902 0.15 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr8_+_119294456 0.15 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr6_-_64029879 0.14 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr10_+_135207623 0.14 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr4_-_100242549 0.14 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr2_+_234826016 0.13 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr17_-_42144949 0.12 ENST00000591247.1
LSM12
LSM12 homolog (S. cerevisiae)
chr12_-_88974236 0.12 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chrX_+_103031421 0.12 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
PLP1
proteolipid protein 1
chr4_-_109684120 0.12 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr12_-_71551652 0.12 ENST00000546561.1
TSPAN8
tetraspanin 8
chr1_+_45241109 0.11 ENST00000396651.3
RPS8
ribosomal protein S8
chr15_-_34610962 0.11 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr2_+_185463093 0.11 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr4_-_48082192 0.11 ENST00000507351.1
TXK
TXK tyrosine kinase
chr2_-_74618964 0.11 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr5_+_140235469 0.11 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr15_-_35047166 0.11 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr2_-_74619152 0.10 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr6_+_26251835 0.10 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr14_+_23012122 0.10 ENST00000390534.1
TRAJ3
T cell receptor alpha joining 3
chr10_-_70231639 0.10 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr11_+_72975559 0.09 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_+_115862858 0.09 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr7_-_140482926 0.09 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr11_+_72975524 0.08 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr4_-_186125077 0.08 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
KIAA1430
chr6_-_155776966 0.08 ENST00000159060.2
NOX3
NADPH oxidase 3
chr12_+_59989918 0.08 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr11_+_72975578 0.08 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_+_75262612 0.08 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr1_+_119957554 0.07 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr16_-_20339123 0.07 ENST00000381360.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr19_+_21264980 0.07 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr2_+_108145913 0.07 ENST00000443205.1
AC096669.3
AC096669.3
chr19_+_47852538 0.06 ENST00000328771.4
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr14_+_102829300 0.06 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr8_+_17354617 0.06 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr14_+_72399833 0.06 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr8_+_27168988 0.06 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr12_+_101988774 0.05 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr7_-_120498357 0.05 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr4_-_153332886 0.05 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr21_-_34863998 0.05 ENST00000402202.1
ENST00000381947.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr12_+_101988627 0.05 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr16_-_15149917 0.05 ENST00000287706.3
NTAN1
N-terminal asparagine amidase
chr16_-_15149828 0.05 ENST00000566419.1
ENST00000568320.1
NTAN1
N-terminal asparagine amidase
chr17_-_76719807 0.05 ENST00000589297.1
CYTH1
cytohesin 1
chr11_-_66964638 0.04 ENST00000444002.2
AP001885.1
AP001885.1
chr19_-_48547294 0.04 ENST00000293255.2
CABP5
calcium binding protein 5
chr11_-_84634217 0.04 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_53662101 0.04 ENST00000371486.3
CPT2
carnitine palmitoyltransferase 2
chr4_-_68749699 0.04 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr6_+_153071925 0.03 ENST00000367244.3
ENST00000367243.3
VIP
vasoactive intestinal peptide
chr4_-_68749745 0.03 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr4_+_71108300 0.03 ENST00000304954.3
CSN3
casein kappa
chr3_-_48956818 0.03 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr12_-_11548496 0.03 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr6_-_24489842 0.03 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr9_-_21217310 0.03 ENST00000380216.1
IFNA16
interferon, alpha 16
chr6_+_32006042 0.02 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr4_+_71248795 0.02 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr12_-_21487829 0.02 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr3_-_47934234 0.02 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr8_+_17354587 0.01 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr1_+_113009163 0.01 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr12_+_14572070 0.01 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr19_-_9006766 0.01 ENST00000599436.1
MUC16
mucin 16, cell surface associated
chr8_+_22424551 0.01 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr16_-_2314222 0.01 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr1_+_144989309 0.01 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr1_-_217262933 0.01 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr13_+_96085847 0.01 ENST00000376873.3
CLDN10
claudin 10
chr5_+_140165876 0.00 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr6_+_26087509 0.00 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr8_-_141810634 0.00 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr5_+_157158205 0.00 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 1.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 2.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.6 3.1 GO:0030070 insulin processing(GO:0030070)
0.3 1.0 GO:1904395 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.2 0.7 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.6 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 0.7 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.5 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.4 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 1.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 1.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 5.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0007379 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1903401 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine transmembrane transport(GO:1903401) L-lysine import into cell(GO:1903410)
0.0 1.1 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.7 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 3.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.6 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 2.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 5.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 1.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.